The arising of smart cities has shown the limitations of the traditional attempts to understand and characterize cities. The smart city marks a relevant step in the evolution of urban systems which is expected to have disruptive impacts in the near future. Indeed, the ‘smartness’ qualification of cities points to relevant changes in the possibilities these complex systems offer mainly due to changes in the information which is made available. This chapter studies the notion of city from an ontological viewpoint, (...) and provides the first elements of a general framework aimed to characterize and unify how to understand the city and its evolution. It starts from historical considerations to isolate the factors that drove the changes from ancient to modern cities, and the complexity that characterizes the nature of cities. Our analysis departs from the traditional views and leads to distinguish three ontological components in the city: the modified physical place, the distributed agentivity, and the knowledge present in the system. The analysis of these components and their interactions, we argue, provides a coherent reading of the city across its evolution steps, and may be used to establish the maturity of today’s smart cities. (shrink)

The field of bioethics is increasingly coming into contact with empirical research findings. In this article, we ask what role empirical research can play in the process of ethical clarification and decision-making. Ethical reflection almost always proceeds in three steps: the description of the moral question,the assessment of the moral question and the evaluation of the decision-making. Empirical research can contribute to each step of this process. In the description of the moral object, first of all, empirical research has a (...) role to play in the description of morally relevant facts. It plays a role in answering the “reality-revealing questions” (what, why,how, who, where and when), in assessing the consequences and in proposing alternative courses of action. Secondly, empirical research plays a role in assessing the moral question. It must be acknowledged that research possesses “the normative power of the factual,” which can also become normative by suppressing other norms. However, inductive normativity should always be balanced out by a deductive form of normativity. Thirdly, empirical research also has a role to play in evaluating the decision-making process. It can rule out certain moral choices by pointing out the occurrence of certain unexpected consequences or effects. It can also be useful, however, as a sociology of bioethics in which the discipline of bioethics itself becomes an object of research. (shrink)

Objectives: The objective of this research is to analyse the evolution and nature of published empirical research in the fields of medical ethics and bioethics.Design: Retrospective quantitative study of nine peer reviewed journals in the field of bioethics and medical ethics .Results: In total, 4029 articles published between 1990 and 2003 were retrieved from the journals studied. Over this period, 435 studies used an empirical design. The highest percentage of empirical research articles appeared in Nursing Ethics , followed by the (...) Journal of Medical Ethics and the Journal of Clinical Ethics . These three journals account for 84.1% of all empirical research in bioethics published in this period. The results of the χ2 test for two independent samples for the entire dataset indicate that the period 1997–2003 presented a higher number of empirical studies than did the period 1990–1996 . This increase is statistically significant . Most empirical studies employed a quantitative paradigm . The main topic of research was prolongation of life and euthanasia .Conclusions: We conclude that the proportion of empirical research in the nine journals increased steadily from 5.4% in 1990 to 15.4% in 2003. It is likely that the importance of empirical methods in medical ethics and bioethics will continue to increase. (shrink)

Our article seeks to demonstrate that Husserl’s approach to intersubjectivity in his First Investigation of 1901/1913 was rigorous rather than rash. To do so, it applies a combination of intentionality and whole-part logic that has been overlooked in Husserl study. It therefore starts from Husserl’s Prolegomena of 1901 to follow his normative phenomenology until it excludes knowledge of another’s consciousness, then unpacks how he does so by his “proofs” in his 1913 Third Investigation, to apply those results to his First (...) Investigation. The outcomes might demonstrate an unexpected rigour in Husserl’s early address to intersubjectivity, and even support a novel logic that considers alterity. (shrink)

We study the bi-embeddability and elementary bi-embeddability relation on graphs under Borel reducibility and investigate the degree spectra realized by these relations. We first give a Borel reduction from embeddability on graphs to elementary embeddability on graphs. As a consequence we obtain that elementary bi-embeddability on graphs is a $\boldsymbol {\Sigma }^1_1$ complete equivalence relation. We then investigate the algorithmic properties of this reduction. We obtain that elementary bi-embeddability on the class of computable graphs is $\Sigma ^1_1$ complete with respect (...) to computable reducibility and show that the elementary bi-embeddability and bi-embeddability spectra realized by graphs are related. (shrink)

Critical Theory: The Key Concepts introduces over 200 widely-used terms, categories and ideas drawing from new historicism, postmodernism, psychoanalysis, Marxism, narratology and other approaches. Entries range from concise definitions to longer explanatory essays and include terms such as :EgoDesireConsumptionHypertextKitschMisogynyQueer StudiesSymbolSuperstructureRaceFeaturing cross-referencing throughout, a substantial bibliography and index, this accessible and easy-to-use guide is an invaluable introduction for anyone studying critical theory.

This thesis investigates the development of ontology as a philosophical discipline in the German philosophical tradition. It starts from what can be considered the invention of ontology and proceeds to the way it was received in the philosophy of Hegel. It is separated into two parts. The first part argues that what can be called the ‘traditional’ form of ontology is developed by Christian Wolff in his 1730 monograph Philosophia prima sive Ontologia, and it traces both the history of the (...) name ‘ontology’, as well as the history of the conception which led to Wolff’s formulation of it. The history of the name tracks the use of the concept ‘ontology’ from its first occurrence in 1606 up to Wolff. The history of the conception tracks the conceptions of various philosophical disciplines, found in thinkers such as Aristotle, Aquinas, and Spinoza, that ultimately give rise to Wolff’s conception of ontology as a science of an entity qua entity. The second part traces the development of this Wolffian conception through the philosophical systems of Kant and Hegel. The aim of this thesis is to argue that Wolff’s philosophy should be seen as the original formulation of the philosophical discipline of ontology and that the Wolffian conception of ontology is the one shared by subsequent German thinkers up to, and including, Hegel. I refer to this shared understanding of what ontology is as ‘the German ontological tradition’. The title of the thesis, The Possibility of Ontology, refers to the way in which this traditional understanding of what ontology is, is treated throughout the German ontological tradition. Specifically, Kant argues that the traditional conception is effectively impossible, while in Hegel one can find arguments that are intended to show that some aspects of this traditional discipline are in fact possible. Besides focusing on a fairly under-researched topic of the early history of ontology as a philosophical discipline, this thesis attempts to utilise its historical findings in order to provide novel ways in which the systems of the thinkers such as Kant and Hegel can be understood. There is a serious disregard for, or underplaying of, the Wolffian influence on the philosophical thought of Kant and Hegel, and it is my aim to contribute to the rectification of this situation by demonstrating the frequently overlooked dialogue these thinkers had with Wolff’s conception of ontology. (shrink)

ABSTRACTSince its origin, bioethics has attracted the collaboration of few social scientists, and social scientific methods of gathering empirical data have remained unfamiliar to ethicists. Recently, however, the clouded relations between the empirical and normative perspectives on bioethics appear to be changing. Three reasons explain why there was no easy and consistent input of empirical evidence into bioethics. Firstly, interdisciplinary dialogue runs the risk of communication problems and divergent objectives. Secondly, the social sciences were absent partners since the beginning of (...) bioethics. Thirdly, the meta‐ethical distinction between ‘is’ and ‘ought’ created a ‘natural’ border between the disciplines. Now, bioethics tends to accommodate more empirical research. Three hypotheses explain this emergence. Firstly, dissatisfaction with a foundationalist interpretation of applied ethics created a stimulus to incorporate empirical research in bioethics. Secondly, clinical ethicists became engaged in empirical research due to their strong integration in the medical setting. Thirdly, the rise of the evidence‐based paradigm had an influence on the practice of bioethics. However, a problematic relationship cannot simply and easily evolve into a perfect interaction. A new and positive climate for empirical approaches has arisen, but the original difficulties have not disappeared. (shrink)

The new wave of ‘foundation models’—general-purpose generative AI models, for production of text (e.g., ChatGPT) or images (e.g., MidJourney)—represent a dramatic advance in the state of the art for AI. But their use also introduces a range of new risks, which has prompted an ongoing conversation about possible regulatory mechanisms. Here we propose a specific principle that should be incorporated into legislation: that any organization developing a foundation model intended for public use must demonstrate a reliable detection mechanism for the (...) content it generates, as a condition of its public release. The detection mechanism should be made publicly available in a tool that allows users to query, for an arbitrary item of content, whether the item was generated (wholly or partly) by the model. In this paper, we argue that this requirement is technically feasible and would play an important role in reducing certain risks from new AI models in many domains. We also outline a number of options for the tool’s design, and summarize a number of points where further input from policymakers and researchers would be required. (shrink)

The field of bioethics is increasingly coming into contact with empirical research findings. In this article, we ask what role empirical research can play in the process of ethical clarification and decision-making. Ethical reflection almost always proceeds in three steps: the description of the moral question,the assessment of the moral question and the evaluation of the decision-making. Empirical research can contribute to each step of this process. In the description of the moral object, first of all, empirical research has a (...) role to play in the description of morally relevant facts. It plays a role in answering the “reality-revealing questions” (what, why,how, who, where and when), in assessing the consequences and in proposing alternative courses of action. Secondly, empirical research plays a role in assessing the moral question. It must be acknowledged that research possesses “the normative power of the factual,” which can also become normative by suppressing other norms. However, inductive normativity should always be balanced out by a deductive form of normativity. Thirdly, empirical research also has a role to play in evaluating the decision-making process. It can rule out certain moral choices by pointing out the occurrence of certain unexpected consequences or effects. It can also be useful, however, as a sociology of bioethics in which the discipline of bioethics itself becomes an object of research. (shrink)

Although many still see Derrida as a thinker opposed to a unified systematic meaning, there has recently been growing recognition that Derrida, in his later years, suggested that his work is not averse to formalisation. In support of this view, this paper points out that, in 1990, Derrida himself told us that his first work of 1954 reveals a “law” which impels his career, and that some responses had arisen even there. Some benefits of adopting such a common pole are (...) set out, and an interrelated “system” developed to relate the law of 1954 to the later responses, in order to help find a common, systematic base for Derrida’s oeuvre. The need to accommodate approaches which are wary of a systematic approach is nevertheless acknowledged, and possible ways of reconciling the diverse readings of Derrida’s intent and collaboratively furthering the formalisation of Derrida’s oeuvre for posterity are outlined in closing. Indo-Pacific Journal of Phenomenology, Volume 10, Edition 2, October 2010: 43-60. (shrink)

The origin of the genetic code has been attributed in part to an accidental assignment of codons to amino acids. Although several lines of evidence indicate the subsequent expansion and improvement of the genetic code, the hypothesis of Francis Crick concerning a frozen accident occurring at the early stage of genetic code evolution is still widely accepted. Considering Crick’s hypothesis, mathematical descriptions of hypothetical scenarios involving a huge number of possible coexisting random genetic codes could be very important to explain (...) the origin and evolution of a selected genetic code. This work aims to contribute in this regard, that is, it provides a theoretical framework in which statistical parameters of error functions are calculated. Given a genetic code and an amino acid property, the functional code robustness is estimated by means of a known error function. In this work, using analytical calculations, general expressions for the average and standard deviation of the error function distributions of completely random codes with standard stop codons were obtained. As a possible biological application of these results, any set of amino acids and any pure or mixed amino acid properties can be used in the calculations, such that, in case of having to select a set of amino acids to create a genetic code, possible advantages of natural selection of the genetic codes could be discussed. (shrink)

This article discusses the relation between empirical and normative approaches in bioethics. The issue of dwarf tossing, while admittedly unusual, is chosen as a point of departure because it challenges the reader to look with fresh eyes upon several central bioethical themes, including human dignity, autonomy, and the protection of vulnerable people. After an overview of current approaches to the integration of empirical and normative ethics, we consider five ways that the empirical and normative can be brought together to speak (...) to the problem of dwarf tossing: prescriptive applied ethics, theoretical ethics, critical applied ethics, particularist ethics and integrated empirical ethics. We defend a position of critical applied ethics that allows for a two-way relation between empirical and normative theories. Against efforts fully to integrate the normative and the empirical into one synthesis, we propose that the two should stand in tension and relation to one another. The approach we endorse acknowledges that a social practice can and should be judged both by the gathering of empirical data and by normative ethics. Critical applied ethics uses a five stage process that includes: (a) determination of the problem, (b) description of the problem, (c) empirical study of effects and alternatives, (d) normative weighing and (e) evaluation of the effects of a decision. In each stage, we explore the perspective from both the empirical (sociological) and the normative ethical point of view. We conclude by applying our five-stage critical applied ethics to the example of dwarf tossing. (shrink)

Derrida became increasingly overt in later years in suggesting that his work displays a rigour, and even a “logic.” Further, it is becoming accepted that deconstruction arose in dialogue with Husserl. In support of these views, this article points out that in 1990 Derrida told us that his first work of 1954 revealsa “law” which guides his career, and that some responses had already arisen there. The work of 1954 is examined, and an interrelated “system” developed by which the responses (...) relate to the law, to help find a common, early and systematic base to apply to Derrida’s oeuvre as it develops. Brief examples will be pointed to in closing to show that this basis subsists, at least in part, in later work. (shrink)

BackgroundCurrent preimplantation genetic testing (PGT) technologies enable embryo genotyping across the whole genome. This has led to the development of polygenic risk scoring of human embryos (PGT-P). Recent implementation of PGT-P, including screening for intelligence, has been extensively covered by media reports, raising major controversy. Considering the increasing demand for assisted reproduction, we evaluated how information about PGT-P is communicated in press media and explored the diversity of ethical themes present in the public debate.MethodsLexisNexis Academic database and Google News were (...) searched to identify articles about polygenic embryo screening. This led to 535 news articles. 59 original articles met the inclusion criteria. Inductive content analysis was used to analyse these articles.Results8.8% of articles gave embryo polygenic scoring a positive portrayal, while 36.8% expressed a negative attitude. 54.4% were neutral, mostly highlighting limited practical value of the technology in in vitro fertilization settings. We identified five main ethical themes that are also present in academic literature and the broader debate on reproductive technologies: a slippery slope towards designer babies, well-being of the child and parents, impact on society, deliberate choice and societal readiness.ConclusionsImplementation of embryo polygenic profiling engenders a need for specific recommendations. Current media analysis discloses important ethical themes to consider when creating future guidelines for PGT-P. (shrink)

Since its origin, bioethics has attracted the collaboration of few social scientists, and social scientific methods of gathering empirical data have remained unfamiliar to ethicists. Recently, however, the clouded relations between the empirical and normative perspectives on bioethics appear to be changing. Three reasons explain why there was no easy and consistent input of empirical evidence into bioethics. Firstly, interdisciplinary dialogue runs the risk of communication problems and divergent objectives. Secondly, the social sciences were absent partners since the beginning of (...) bioethics. Thirdly, the meta‐ethical distinction between ‘is’ and ‘ought’ created a ‘natural’ border between the disciplines. Now, bioethics tends to accommodate more empirical research. Three hypotheses explain this emergence. Firstly, dissatisfaction with a foundationalist interpretation of applied ethics created a stimulus to incorporate empirical research in bioethics. Secondly, clinical ethicists became engaged in empirical research due to their strong integration in the medical setting. Thirdly, the rise of the evidence‐based paradigm had an influence on the practice of bioethics. However, a problematic relationship cannot simply and easily evolve into a perfect interaction. A new and positive climate for empirical approaches has arisen, but the original difficulties have not disappeared. (shrink)

This book is intended as a historical and critical study on the origin of the equations of motion as established in Newton's Principia. The central question that it aims to answer is whether it is indeed correct to ascribe to Galileo the inertia principle and the law of falling bodies. In order to accomplish this task, the study begins by considering theories on the motion of bodies from classical antiquity, and especially those of Aristotle. The theories developed during the Middle (...) Ages and the Renaissance are then reviewed, with careful analysis of the contributions of, for example, the Merton and Parisian Schools and Galileo's immediate predecessors, Tartaglia and Benedetti. Finally, Galileo's work is examined in detail, starting from the early writings. Excerpts from individual works are presented, to allow the texts to speak for themselves, and then commented upon. The book provides historical evidence both for Galileo's dependence on his forerunners and for the major breakthroughs that he achieved. It will satisfy the curiosity of all who wish to know when and why certain laws have been credited to Galileo. (shrink)

This article aims to restore a way to approach Derrida by revisiting the essentialist ‘logic’ that Leonard Lawlor put forward in 2002. Lawlor argues that the early Derrida developed a ‘logic of totality’ from Hyppolite's reading of Hegel, which formed the basis for a ‘logic of contamination’ and différance; moreover, Lawlor demonstrated such progress. We will situate his implicit premises before following his sequential argument, and thus isolate how Lawlor is aware that Derrida disputes Hyppolite's basic premises and outcomes, so (...) as to suggest the difficulty is methodological. By that we will support Lawlor's discovery that Derrida's earliest work can be approached ‘logically’, so as to help re-orientate both an approach and strands of thought that Derrida helped to inspire. (shrink)

This article examines Paul Guyer’s claim that we should attempt to ground the principle of religious freedom on the basis of Kant’s arguments for religious liberty. I problematise Guyer’s suggestion by investigating a hypothetical ‘dogmatic conflict’ between a scientifically and a religiously grounded belief. I further suggest that considering Christian Wolff’s philosophy might provide us with an approach which shares the benefits that Guyer identifies in Kant, while at the same time avoiding the issues Kant might run into that result (...) from the occurrence of the dogmatic conflict. I start by providing a background to Wolff’s philosophy and explaining the notion of the dogmatic conflict. Then I present a potential contemporary case of the dogmatic conflict and try to see how it would be dealt with based on Guyer’s proposal. Finally, I consider what a Wolffian solution would look like, arguing that Guyer’s project might benefit from considering Wolff. (shrink)

This paper presents Christian Wolff’s claim that philosophy, undertaken on the basis of a proper method, cannot contradict revealed religion. The paper first provides a context of Wolff’s banishment from Halle for holding views in conflict with religious doctrines. Next, it proceeds, on the basis of Wolff’s Discursus præliminaris de philosophia in genere prefixed to his 1728 Latin Logic, to explain the principles of Wolff’s method, and to show how his conception of method enables him to disallow the possibility of (...) a genuine conflict between philosophical and religious dogmas. For Wolff, doctrinal conflicts between philosophy and revealed religion can only occur as a result of terminological disagreements, disagreements between dogmas and hypotheses, or disagreements between dogmas and theological misinterpretations. The actual conflict of dogmas, understood as religious or philosophical truths, Wolff holds to be impossible. (shrink)

The increasing implementation of next-generation sequencing technologies in the clinical context and the expanding commercial offer of genetic tests directly-toconsumers has increased the availability of previously inaccessible genetic information. A particular concern in both situations is how the volume of novel information will affect the processing of genetic and genomic information from minors. For minors, it is argued that in the provision of genetic testing, their “right not to know” should be respected as much as possible. Testing a minor early (...) in life eliminates the possibility for the minor to make use of his or her “right not to know.” The article discusses the theoretical underpinnings of the right not know, analyzes reasons why various direct-to-consumer companies process samples from minors, and discusses the right not to know in relation to common complex disorders in a pediatric population. (shrink)

Is some form of epoché possible on theological concepts? In which way? Is it possible consider their importance leaving their religious scope aside? Can the theological concepts tell us something unless we consider their essential reference to our relationship with a divine being? The answer to these questions let us to understand what means to be a secular scholar of medieval philosophy. It's impossible conversely to discuss this problem without dealing with medieval theology. And this concerns not only the nature (...) of theology, but also and deeply the same idea of secularism . Therefore a fully aware historiography of medieval thought has to understand the theological speech and to encounter the depth of this theoretical question. So we can conclude that for a secular reading of the medieval theology is paradoxically essential to catch the intimate sense of religious thought and the historically defined forms of its actual conceptualizations. (shrink)

Fourteenth- and fifteenth-century current historiography doesn't seem to offer a satisfactory reconstruction of medieval terminism, so as to be able to solve the problems of interpretation regarding to the notion of ‘intensio’. In order to analyse appropriately the relationship between the notion of ‘intensio’ and the mathematical representation of its ‘latitudo’, a thorough examination of the semantic nature of the notions of intensive qualities and of their logical behaviour is here attempted.

In Boccacio's Decameron, Cervigni sees a parodic echo of the circles of Dante's Divine Comedy, and asks whether Bocaccio envisions the voyage of the brigata as similar to Dante the Pilgrim's journey toward the center, first the abysmal center of Lucifer, then towards the highest center, God.

In order to study the relationship between genes and diseases, the increasing availability and sharing of phenotypic and genotypic data have been promoted as an imperative within the scientific community. In parallel with data sharing practices by clinicians and researchers, recent initiatives have been observed in which individuals are sharing personal genomic data. The involvement of individuals in such initiatives is facilitated by the increased accessibility of personal genomic data, offered by private test providers along with availability of online networks. (...) Personal webpages and on-line data sharing platforms such as Consent to Research, Free the Data, and Genomes Unzipped are being utilized to host and share genotypes, electronic health records and family history uploaded by individuals. Although personal genomic data sharing initiatives vary in nature, the emphasis on the individuals’ control on their data in order to benefit research and ultimately health care has seen as a key theme across these initiatives. In line with the growing practice of personal genomic data sharing, this paper aims to shed light on the potential challenges surrounding these initiatives. As in the course of these initiatives individuals are solicited to individually balance the risks and benefits of sharing their genomic data, their awareness of the implications of personal genomic data sharing for themselves and their family members is a necessity. Furthermore, given the sensitivity of genomic data and the controversies around their complete de-identifiability, potential privacy risks and harms originating from unintended uses of data have to be taken into consideration. (shrink)

_Brill’s Companion to the Reception of Athenian Democracy_ delivers a fresh and wide-ranging analysis of the uses and reinterpretations of ancient Greek democracy from the late Middle Ages to the XXI century, offering a comprehensive and multidisciplinary approach to this important topic.

This essay considers the tradition of criticism against Athenian democracy, in both ancient and modern times. Often this critical tradition has been seen to adduce greater interest than the very democratic experience from which it arose; in this it has been aided, in part, by the asserted absence of an ancient theory of democracy. Yet there are significant traces of a democratic theory in the ancient sources, which ought to serve both as a theoretical and ideological riposte to the critics. (...) Some of the modern objections to classical Athenian democracy take up the argument of the ancient critics and display an anti-democratic orientation. Others, however, are motivated by a certain sensibility, grown out of liberalism and the legal state, as well as the emancipation of women and the abolition of slavery. Nevertheless, these objections are sometimes lacking in historical perspective. If we reassess Athenian democracy, it may yet be seen to constitute a useful point of reference, at a time when the current model of democracy finds its legitimacy questioned.2. (shrink)

Participation in healthcare decision-making is considered to be an important right of minors, and is highlighted in both international legislation and public policies. However, despite the legal recognition of children’s rights to participation, and also the benefits that children experience by their involvement, there is evidence that legislation is not always translated into healthcare practice. There are a number of factors that may impact on the ability of the child to be involved in decisions regarding their medical care. Some of (...) these factors relate to the child, including their capacity to be actively involved in these decisions. Others relate to the family situation, sociocultural context, or the underlying beliefs and practices of the healthcare provider involved. In spite of these challenges to including children in decisions regarding their clinical care, we argue that it is an important factor in their treatment. The extent to which children should participate in this process should be determined on a case-by-case basis, taking all of the potential barriers into account. (shrink)