The Search for the Legacy of the USPHS Syphilis Study at Tuskegee is a collection of essays from experts in a variety of fields seeking to redefine the legacy of the infamous Tuskegee Syphilis Study. The essayists place the legacy of the study within the evolution of racial and ethnic relations in the United States. Contributors include two leading historians on the study, two former United States Surgeons General, and other prominent scholars from a wide range of fields.

Census data from Australia, Canada, and the United Kingdom make clear that the irreligious as well as those who indicate No Religion in censuses are growing rapidly. Despite being dominated by young males, we find that the demographics of those who identify with some form of irreligion or who indicate they have no religion are becoming more gender balanced and are rising in age. However, we also find that atheists, agnostics, and humanists are not having children, meaning their current remarkable (...) rate of growth will fall off in the near future. In contrast, ‘Nones’ are more fertile than the population at large. However, because more than a few Nones hold religious beliefs, it is difficult to predict how the growth of this portion of the population will impact the future growth of irreligion. We conclude that more empirical work needs to be carried out on the Nones. (shrink)

In many research studies, tumor biopsies are an unavoidable requirement for achieving key scientific aims. Yet some commentators view mandatory research biopsies as coercive and suggest they should be optional, or at least optional until further data are obtained regarding their scientific usefulness. Further complicating the ethical picture is the fact that some research biopsies offer a potential for clinical benefit to trial participants. We interviewed and surveyed a convenience sample of participants in phase I clinical trials at a single (...) institution. Our primary aim was to describe phase I participants’ understanding of whether a research biopsy offered them the prospect of medical benefit. We also endeavored to describe participants’ views about biopsies—specifically, the benefits of biopsies, if any, and whether biopsies were acceptable, risky, or discouraged trial participation. Finally, we collected data on demographics and attitudes to see if any strong correlations with misunderstanding, acceptability, or riskiness existed. Overall, the respondents tended to view research biopsies as acceptable, though they did not succeed in identifying the lack of benefit of a research biopsy. These findings call for renewed efforts in consent conversations and documents to carefully describe the benefits, or lack thereof, of research biopsies. (shrink)

The victory of Ellerman's technetronic civilization is indeed a fearful prospect, but one that is much less plausible than he allows. His imagined makers, as was pointed out forty odd years ago by C. S. Lewis, could themselves have no criterion of right action or right belief, nor could they sensibly expect ? either on secular or on thcistic suppositions ? to be able to control the world forever.

The increasing use of pharmacotherapy raises specific ethical concerns for psychologists working with vulnerable populations. Due to a shortage of trained specialists, professionals without training in mental health, such as primary care providers, are increasingly prescribing and monitoring psychotropic medications. Vulnerable populations face additional barriers to mental health treatment and are at heightened risk when these factors intersect. Hence, these patients experience unique barriers to receiving optimal psychopharmacological care and are differentially vulnerable to deleterious outcomes associated with misdiagnosis and overmedication. (...) Taken together, these factors fuel inequities in the access, quality, and utilization of mental health care. Psychologists working with these patients are ethically mandated to protect patients from harm and ensure equitable care across patient populations. Specifically, psychologists must respond to the dilemma of how to effectively treat patients within these vulnerable populations who have been misdiagnosed or poorly medicated while remaining within the bounds of their competence. This article recommends pathways to address these dilemmas through education, training, research, and advocacy. (shrink)

This book is a collection of secondary essays on America's most important philosophic thinkers—statesmen, judges, writers, educators, and activists—from the colonial period to the present. Each essay is a comprehensive introduction to the thought of a noted American on the fundamental meaning of the American regime.

De nombreux philosophes noirs donneraient cher pour avoir pris un café avec Jean-Paul Sartre. Si nous en avions la possibilité, beaucoup d’entre nous commenceraient par le remercier de son courage. Il a lutté non seulement contre les forces anti-humaines de la société française et de la société américaine, mais aussi contre ces forces en lui qui proposaient toujours la séduction d’une..

De nombreux philosophes noirs donneraient cher pour avoir pris un café avec Jean-Paul Sartre. Si nous en avions la possibilité, beaucoup d’entre nous commenceraient par le remercier de son courage. Il a lutté non seulement contre les forces anti-humaines de la société française et de la société américaine, mais aussi contre ces forces en lui qui proposaient toujours la séduction d’une...

This article examines an Africana philosophy of culture of black existence through, after offering a critique of a theodicy of textuality and social reality, exploration of the construction of “problem people,” of people whose existence, marked by blackness, has been treated as a challenge to reason and the search for knowledge in the modern world. As Africana philosophy raises concerns of philosophical anthropology, philosophy of freedom, and a metacritique of reason, it offers, as well, a case for the central importance (...) of philosophy of culture in modern and late modern thought. (shrink)

This article examines an Africana philosophy of culture of black existence through, after offering a critique of a theodicy of textuality and social reality, exploration of the construction of “problem people,” of people whose existence, marked by blackness, has been treated as a challenge to reason and the search for knowledge in the modern world. As Africana philosophy raises concerns of philosophical anthropology, philosophy of freedom, and a metacritique of reason, it offers, as well, a case for the central importance (...) of philosophy of culture in modern and late modern thought. (shrink)

Pancreatitis is a complex, progressively destructive inflammatory disorder. Alcohol was long thought to be the primary causative agent, but genetic contributions have been of interest since the discovery that rare PRSS1, CFTR and SPINK1 variants were associated with pancreatitis risk. We now report two associations at genome-wide significance identified and replicated at PRSS1-PRSS2 and X-linked CLDN2 through a two-stage genome-wide study. The PRSS1 variant likely affects disease susceptibility by altering expression of the primary trypsinogen gene. The CLDN2 risk allele is (...) associated with atypical localization of claudin-2 in pancreatic acinar cells. The homozygous CLDN2 genotype confers the greatest risk, and its alleles interact with alcohol consumption to amplify risk. These results could partially explain the high frequency of alcohol-related pancreatitis in men. © 2012 Nature America, Inc. All rights reserved. (shrink)

In 2012, the Church of Scientology’s Mission in Haifa, Israel, defected from the Church and reestablished itself as the independent Dror Center. The precipitatingevent was a critical email sent by high-ranking Scientologist Debbie Cook to her contacts throughout the Scientology world. The core of her critique was that theChurch was in decline – a decline she attributed to policies that deviated from guidelines set forth by Scientology’s founder, L. Ron Hubbard. The present paperanalyzes the current legitimation crisis within the Church (...) of Scientology through the twin lenses of the Cook letter and the Haifa schism. (shrink)

For the past 30 years, Paget Henry has been one of the most articulate and creative voices in Caribbean scholarship, making seminal contributions to the study of Caribbean political economy, C.L.R. James studies, critical theory, phenomenology, and Africana philosophy. This volume includes some of his most important essays from across his remarkable career, providing an introduction to a broad range of pressing contemporary themes and to the unique mind of one of the leading Caribbean intellectuals of his generation.

What did C. S. Lewis think about truth, goodness and beauty? Fifteen essays explore three major philosophical themes from the writings of Lewis--Truth, Goodness and Beauty. This volume provides a comprehensive overview of Lewis's philosophical thinking on arguments for Christianity, the character of God, theodicy, moral goodness, heaven and hell, a theory of literature and the place of the imagination.

We say that A≤LRB if every B-random set is A-random with respect to Martin–Löf randomness. We study this relation and its interactions with Turing reducibility, classes, hyperimmunity and other recursion theoretic notions.

Les arts de la ruse constituent un champ exploratoire où se tissent et se recroisent des pratiques tant réflexives que non-réflexives: des tactiques animales de chasse ou de camouflage aux adresses agiles de scientifiques pour construire des théories pertinentes. Michel de Certeau, jésuite érudit, au carrefour des tournants linguistique et pragmatique de la fin du XXe siècle, a travaillé ce tissage insolite de pratiques à travers les sciences humaines, questionnant et braconnant tour à tour les ruses du théoricien et celles (...) de l'objet qu'il convoque : l'historien et le passé, l'ethnologue et la culture, le sociologue et le quotidien, le théologien et la mystique... L'étendue et la diversité des thèmes rigoureusement abordés par cet auteur inclassable lance un jeu d'adresses à ses lecteurs : Michel de Certeau nous demande à notre tour de ruser, autrement dit de saisir l'occasion de transformer le champ du savoir en évitant de tomber de Charybde en Scylla. Pour relever ce défi et y inviter, à leur tour, les lecteurs, cet ouvrage propose un "tango philosophique", danse par excellence d'une ruse permanente entre technique sophistiquée de pas et improvisation envoûtée, à partir des traces de pieds nus, laissés par Michel de Certeau, sur le bord de nos savoirs conquérants. Cette étude développe une expérimentation épistémologique des sciences humaines contemporaines. (shrink)

The notion of autonomy commonly employed in medical ethics literature and practices is inadequate on three fronts: it fails to properly identify nonautonomous actions and choices, it gives a false account of which features of actions and choices makes them autonomous or nonautonomous, and it provides no grounds for the moral requirement to respect autonomy. In this paper I offer a more adequate framework for how to think about autonomy, but this framework does not lend itself to the kinds of (...) practical application assumed in medical ethics. A general problem then arises: the notion of autonomy used in medical ethics is conceptually inadequate, but conceptually adequate notions of autonomy do not have the practical applications that are the central concern of medical ethics. Thus, a revision both of the view of autonomy and the practice of “respect for autonomy” are in order. (shrink)

Interpersonal understanding is rooted in social engagement. The question is: How? What features of intersubjective coordination are essential for the growth of concepts about the mind, and how does development proceed on this basis? Carpendale & Lewis (C&L) offer many telling insights, but their account begs questions about the earliest forms of self-other linkage and differentiation, especially as mediated by processes of identification.