Clinical research under the usual regulatory constraints may be difficult or even impossible in a public health emergency. Regulators must seek to strike a good balance in granting as wide therapeutic access to new drugs as possible at the same time as gathering sound evidence of safety and effectiveness. To inform current policy, I reexamine the philosophical rationale for restricting new medicines to clinical trials, at any stage and for any population of patients (which resides in the precautionary principle), to (...) show that its objective to protect public health, now or in the future, could soon be defeated in a pandemic. Providing wider therapeutic access and coordinating observations and natural experiments, including service delivery by cluster (wedged cluster trials), may provide such a balance. However, there are important questions of fairness to resolve before any such research can proceed. (shrink)

How do we know that our own actions belong to us? How are we able to distinguish self-generated sensory events from those that arise externally? In this paper, I will briefly discuss experiments that were designed to investigate these questions. In particularly, I will review psychophysical and neuroimaging studies that have investigated how we recognise the consequences of our own actions, and why patients with delusions of control confuse self-produced and externally produced actions and sensations. Studies investigating the failure of (...) this 'self-monitoring' mechanism in patients with delusions of control will be discussed in the context of the hypothesis that overactivity in the parietal cortex and the cerebellum contribute to the misattribution of an action to an external source (). (shrink)

This paper offers observations on people’s lived experience of the food system in Michigan during the early Covid-19 pandemic as an initial critical foray into the everyday pandemic food world. The Covid-19 crisis illuminates a myriad of adaptive food behaviors, as people struggle to address their destabilized lives, including the casual acknowledgement of the pandemic, then anxiety of the unknown, the subsequent new dependency, and the possible emergence of a new normal. The pandemic makes the injustices inherent in the food (...) system apparent across communities, demonstrating that food injustice destabilizes all members of the food system, regardless of their social location. The challenges of eating in a pandemic also reinforce the importance of building a sustainable food system; the challenges of food sovereignty and food sustainability are inextricably linked, and the pandemic lays this bare. (shrink)

The topics of equity, diversity, inclusion, decolonization, and Indigenization have been neglected in academic and research integrity. In this article, I offer examples of how these issues are being addressed and argue that academic integrity networks and organizations ought to develop intentional strategies for equity, diversity and inclusion, and decolonization in terms of leadership, scholarship, and professional opportunities. I point out that existing systems perpetuate the conditions that allow for overrepresentation of reporting among particular student groups including international students, students (...) of colour, and those for whom English is an additional language. I conclude with concrete recommendations for action. (shrink)

We consider VC-minimal theories admitting unpackable generating families, and show that in such theories, forking of formulae over a model M is equivalent to containment in global types definable over M, generalizing a result of Dolich on o-minimal theories in [4].

In English, two deictic space-time metaphors are in common usage: the Moving Ego metaphor conceptualizes the ego as moving forward through time and the Moving Time metaphor conceptualizes time as moving forward toward the ego . Although earlier research investigating the psychological reality of these metaphors has typically examined spatial influences on temporal reasoning , recent lines of research have extended beyond this, providing initial evidence that personality differences and emotional experiences may also influence how people reason about events in (...) time . In this article, we investigate whether these relationships have force in real life. Building on the effects of individual differences in self-reported conscientiousness and procrastination found by Duffy and Feist , we examined whether, in addition to self-reported conscientiousness and procrastination, there is a relationship between conscientious and procrastinating behaviors and temporal perspective. We found that participants who adopted the Moving Time perspective were more likely to exhibit conscientious behaviors, while those who adopted the Moving Ego perspective were more likely to procrastinate, suggesting that the earlier effects reach beyond the laboratory. (shrink)

The right to health care is a right to care that is not too costly to the provider, considering the benefits it conveys, and is effective in bringing about the level of health needed for a good human life, not necessarily the best health possible. These considerations suggest that, where possible, society has an obligation to provide preventive health care, which is both low cost and effective, and that health care regulations should promote citizens’ engagement in reasonable preventive health care (...) practices. (shrink)

In three studies, we explored the retention and transfer of tool-making knowledge, learnt from an adult demonstration, to other temporal and task contexts. All studies used a variation of a task in which children had to make a hook tool to retrieve a bucket from a tall transparent tube. Children who failed to innovate the hook tool independently saw a demonstration. In Study 1, we tested children aged 4 to 6 years (N = 53) who had seen the original demonstration (...) 3 months earlier. Performance was excellent at the second time, indicating that children’s knowledge was retained over the 3 month period. In Studies 2 and 3 we explored transfer of the new knowledge to other tasks. In Study 2, children were given two variants of the apparatus that differed in surface characteristics (e.g. shape and colour). Participants generalised their knowledge to these new apparatuses even though the new pipecleaner also differed in size and colour. Five- to 6-year-olds (n = 22) almost always transferred their knowledge to problems where the same tool had to be made. Younger, 3- to 5-year-olds’ (n = 46), performance was more variable. In Study 3, 4- to 7-year-olds (N = 146) saw a demonstration of hook making with a pipecleaner, but then had to make a tool by combining pieces of wooden dowel (or vice versa: original training on dowel, transfer to pipecleaner). Children did not transfer their tool-making knowledge to the new material. Children retained tool-making knowledge over time and transferred their knowledge to new situations in which they needed to make a similar tool from similar materials, but not different materials. We concluded that children’s ability to use tool-making knowledge in novel situations is likely to depend on memory and analogical reasoning, with the latter continuing to develop during middle childhood. (shrink)

This is the first in a series of five papers on the role, remit and function of research ethics committees which are intended to provide for REC members a broad understanding of the most important issues in research ethics and governance. The first considers the rationale for having ethics review by committee at all; seeking to explain why ethics committees, as we currently have them, are so important to the wider system of governing research.

Environmental change requires individuals and institutions to facilitate adaptive governance. However, facilitating adaptive governance may be difficult because resource users' perceptions of desirable ways of life vary. These perceptions influence preferences related to environmental governance and may stem from the ways individuals subjectively value their work and their connections to their environment. This paper uses a value-based approach to examine individual and institutional preferences for adaptive governance in Carelmapu, Chile. We show that two groups had different value frames rooted in (...) divergent ontologies which influenced their actions related to adaptive governance, creating conflict. (shrink)

In fisheries biology of the late 19th century, the challenges posed to taxonomy by Darwinian theory intersected with attempts to increase the productivity of marine populations. Addressing both discourses, the influential German zoologist Friedrich Heincke developed a set of methods to determine exactly the differences between varieties or races of herring. In taxonomy, his methods contributed to the development of a biological species concept; in fisheries biology, they allowed tracing the herrings' migrations, which ultimately aided in divising schemes for sustainable (...) fisheries. Heincke's use of mathematical statistics, some of them borrowed from anthropometry, served to distinguish his ‚exact’ approach from that of typological taxonomists. Beyond its use as a rhetorical ploy, exactness gained meaning in the epistemic regime of exact reproduction of measurements, which entailed the replication of measurement techniques for the purpose of comparison e.g. of herrings caught at different locations. This exactness was enabled by the formalisation of the process of taxonomic identification. (shrink)

Volume 20, Issue 9, September 2020, Page 39-41.

Over one in five adults in the United States and around the world are estimated to live with chronic pain. How are we to attend well to persons living with pain? This is a difficult, pressing question for both healthcare institutions and Christian communities, and it is only made more complex both by the contemporary opioid crisis and by how experiences of pain and addiction are shaped in the American context by race, gender, and class. Attending faithfully to persons in (...) pain demands thoughtful, creative resources on both practical and conceptual levels. In this special issue of Christian Bioethics, eight scholars from different disciplines—Sarah Barton, Farr Curlin, Jaime Konerman-Sease, Brett McCarty, Joel Shuman, Devan Stahl, John Swinton, and Emmy Yang—engage the meaning of attending to persons in pain for Christian bioethics and for faithful Christian practice. (shrink)

Early modern natural philosophers such as Francis Bacon are frequently seen as providing a legitimating ideology for British imperial expansion. Although this has been challenged by one recent study, much of Bacon's work on English colonisation remains unexplored. This article argues that far from being an ideological apologist for English colonisation, Bacon had two sets of colonial anxieties. The first derived from a tradition of civic humanism which concerned the moral corruption, dispossession of indigenous people and the greed involved in (...) the British colonization of Ireland and America. Bacon's second anxiety was not moral but epistemological, and stemmed from his natural philosophy. For Bacon, colonies were not simply new commonwealths, they were places which potentially produced the natural knowledge vital for the recreation of man's original, epistemic empire over the world. Consequently, Bacon was not only interested in the morality of colonising, but also whether the knowledge produced in colonies was reliable. An exploration of Bacon's views on colonisation also offers us a point of entry into the scholarly debate about the relationship between Bacon's natural philosophy and his political thought. (shrink)

In Republic X, the “problem of the irrational part” is this: Greek tragedy interacts with non-reasoning elements of the soul, affecting audiences in ways that undermine their reasoned views about virtue and value. I suggest that the common construal of Socrates’s critique of Greek tragedy is inadequate, in that it belies key elements of Plato’s audience psychology; specifically, the crucial role of the spirited part and the audience’s cognitive contribution to spectatorship. I argue that Socrates’s emphasis on the audience’s cognitive (...) contribution to spectatorship allows him to anticipate a non-authoritarian solution to the problem of the irrational part. (shrink)

The relevance of context has been acknowledged also recently as a fundamental element for the correct evaluation of argumentative moves within institutional fields of interaction. Indeed, not considering the larger culture-specific and social features of the context within which the interactions take place poses problems of interpretation of the data and comparability of results. Starting from these considerations, the paper aims at discussing a model for the description of the social context of interaction that may allow for a better interpretation (...) and evaluation of argumentative moves within medical consultations. The efficacy of the model is shown by applying it to the description and analysis of examples of real-life consultations recorded in the Italian region of Lombardy. In the first section, the model for the description of the social context of interaction is presented and discussed. In the second section, examples of argumentative passages from a selection of consultations are presented and commented on by relying on the model. Some concluding remarks and further developments of the research are proposed in the final section Keywords: communication context, argumentation in context, situated discourse, medical consultation. (shrink)

By offering us a voice that is both at a distance and inside one's own head, the telephone causes interference in thinking and writing. But despite the multiple telephones that echo in and across Jacques Derrida's work, and specifically his writing to and with Hélène Cixous, it is only since Derrida's death that critical interest in the phone has fully emerged, with work by Royle (2006), Prenowitz (2008), Bennington (2013) and Turner (2014) stressing the value of staying on the line. (...) Engaging with Derrida, however, is not simply a matter of picking up the receiver. For the telephone is also, Derrida insists in H.C. for Life (2006), a ‘poetico-technical invention’, that is, the telephone is ‘thought itself’. This paper is about how the telephone ‘thinks’ Derrida, about how it remembers Derrida, and about how it offers us a line for re-imagining his voice. Bound up with the uncanny mechanisms of the telephone, it invites readers to participate in long-distance calling – listening across species, texts and worlds. (shrink)

In this paper, I examine some of the presuppositions that underpin the practice and interpretation of multi-person dialogue – that is, in contexts involving more than two interlocutors – with particular thought for the university seminar. I outline the ‘dialogical phenomenology’ of Beata Stawarska as useful on this count; however, I argue that Stawarska’s account is steeped in a philosophical ‘dyadic paradigm’ which has limiting consequences for practitioners of dialogue looking to understand the nature of dialogue in a group context. (...) Against this paradigm, I argue that there are many varieties of intersubjectivity that have not been widely discussed, including we-you, we-yous, I-yous and we-they intersubjective structures. I will look further at how an understanding of these structures is valuable for dialogue within educational praxes and for the Humanities more broadly. (shrink)

In this paper I argue that there are gestalt principles underlying intersubjective interactions and that this means that intersubjective ‘units’, can be recognised as unified gestalt wholes. The nub of the claim is that interactions within a ‘plural subject’ can be perceived by others outside this plural subject. Framed from the first-person perspective: I am able to recognise intersubjective interactions between multiple others who are not me. I argue that the terminology of gestalt structures is helpful in framing and understanding (...) the non-reducible make-up of these relational units. I consequently defend the legitimacy of the claim that we can attend to more than one other person at once, holding multiple others as a single focus of attention insofar as we can attend to multiple others as a gestalt whole. I argue that it is therefore legitimate to talk about attending to, perceiving and addressing multiple others at the same time, in the second-person plural. I argue that this can be identified in the phenomenology of such interactions and in an analysis of the core underlying structures of these interactions. (shrink)

Name der Zeitschrift: Zeitschrift für Religionswissenschaft Jahrgang: 25 Heft: 1 Seiten: 132-158.

Lochlann Jain's debut non-fiction graphic novel, Things That Art, playfully interrogates the order of things. Toying with the relationship between words and images, Jain's whimsical compositions may seem straightforward. Upon closer inspection, however, the drawings reveal profound and startling paradoxes at the heart of how we make sense of the world. Commentaries by architect and theorist Maria McVarish, poet and naturalist Elizabeth Bradfield, musician and English Professor Drew Daniel, and the author offer further insight into the drawings in this collection. (...) A captivating look at the fundamental absurdities of everyday communication, Things that Art jolts us toward new forms of collation and collaboration. (shrink)

Abstract Can the wise person be fooled? The Stoics take a very strong view on this question, holding that the wise person (or sage) is never deceived and never believes anything that is false. This seems to be an implausibly strong claim, but it follows directly from some basic tenets of the Stoic cognitive and psychological world-view. In developing an account of what wisdom really requires, I will explore the tenets of the Stoic view that lead to this infallibilism about (...) wisdom, and show that many of the elements of the Stoic picture can be preserved in a more plausible fallibilist approach. Specifically, I propose to develop a Stoic fallibilist virtue epistemology that is based on the Stoic model of the moral virtues. This model of the intellectual virtues will show that (in keeping with a folk distinction) the wise person is never befooled, though that person might be fooled. Content Type Journal Article Pages 1-14 DOI 10.1007/s12136-012-0158-0 Authors Sarah Wright, Department of Philosophy, University of Georgia, 107 Peabody Hall, Athens, GA 30602, USA Journal Acta Analytica Online ISSN 1874-6349 Print ISSN 0353-5150. (shrink)

This is the fourth in a series of five papers on the role, remit and function of research ethics committees which are intended to provide for REC members a broad understanding of the most important issues in research ethics and governance. This paper explores the role of ethics committees in reviewing proposed conditions for recruiting human subjects and in checking the intended procedures for gaining consent. In so doing the paper will reiterate the conditions which are traditionally thought to make (...) consent valid, identify a number of limitations to meeting these conditions, and show when consent, however broadly construed or indeterminately focused, may be unnecessary. (shrink)