This paper makes the case for a revision of contemporary forms of political realism in political theory. I argue that contemporary realists have gone awry in increasingly centring their approach around a metaethical claim: that political theory should be rooted in a political form of normativity that is distinct from moral normativity. Several critics of realism have argued that this claim is unconvincing. But I suggest that it is also a counterintuitive starting point for realism, and one unnecessary to avoid (...) the ‘applied morality’ approach to political theory that realists oppose. Instead, realism should be methodologically orientated around what I term ‘empirically constitutive political realities’ - enduring features of real political contexts that are systematically consequential in their normative implications. Realists can persuasively argue that such empirically constitutive political realities must be attended to in political theory-building, and not merely treated as a context in which independently formulated moral theories are simply applied. This framing of realism accords real politics a genuinely foundational theoretical role, but without requiring any contentious metaethical stance about a non-moral political normativity. I explain some methodological implications that follow for realism – in particular the need to prioritise empirically grounded theorisation of real political contexts over abstract and rather essentialist claims about ‘the political’. I also argue that such a framing of realism helps engender a more accurate, less divisive, and more pluralist conception of methodological debates within political theory. (shrink)

The use of informational terms is widespread in molecular and developmental biology. The usage dates back to Weismann. In both protein synthesis and in later development, genes are symbols, in that there is no necessary connection between their form (sequence) and their effects. The sequence of a gene has been determined, by past natural selection, because of the effects it produces. In biology, the use of informational terms implies intentionality, in that both the form of the signal, and the response (...) to it, have evolved by selection. Where an engineer sees design, a biologist sees natural selection. (shrink)

Marshall et al. (2024) raise questions regarding patient refusals of care. In this commentary we address refusals of care from the lens of patient autonomy and provide suggestions for patient cente...

Concentrating on problems that commonly perplex general readers and beginning students, John Maynard Smith discusses fundamental issues in biology, with emphasis on evolution, development, and cognition. He provides a nontechnical account of molecular genetics, which is the foundation of modern biology, and explores such issues as heredity, animal behavior, the definition and origin of life, the brain and how we know things, artificial and natural intelligence, and genetics. The book is unique in presenting modern ideas in terms that can (...) be understood without an in-depth knowledge of biology. (shrink)

Fodor and Lepore, in their recent book "Holism," maintain that if an inference from semantic anatomism to semantic holism is allowed, certain fairly deleterious consequences follow. In Section 1 Fodor and Lepore's terminology is construed and amended where necessary with the result that the aforementioned deleterious consequences are neither so apparent nor straightforward as they had suggested. In Section 2 their "Argument A" is considered in some detail. In Section 3 their "argument attributed to Quine" is examined at length and (...) a shorter and more perspicacious argument suggested which avoids their charge that the Quinean argument is guilty of an equivocation on the word 'statement'. (shrink)

Federal regulations require that the level of risk posed by pediatric research be classified as “minimal,” “greater than minimal,” or “a minor increase over minimal.” Interpretation of the meaning of the levels has produced a significant literature exploring the ethical basis for making these determinations. This article examines the ethical basis of a variety of approaches proposed in the literature for classifying pediatric research risk. These approaches strive to take into account how society decides which risks are routinely accepted for (...) children outside of research. It is concluded that ways of classifying risk should compare research risks to normal risks for children without special disability and take into account the concerns of the research subject’s community. (shrink)

In Southeast Asian countries (SEA), road transport accounts for the main energy consumption and CO2 emission. Air pollution is a major concern in densely populated cities such as Bangkok, Manila, and Kuala Lumpur. The main objective of this paper is to give insights on trends of transport development, car ownership, and CO2 emissions in Southeast Asia. This study also attempts to review the successful transportation policies around the globe and to introduce the possible instruments that can help reduce air pollution (...) in Southeast Asian countries. Economic instruments to estimate the benefits of a cleaner environment due to new policies are introduced as well. The results of this research could help policy makers consider approaches that could internalize external costs of transportation and maximize the societal welfare. (shrink)

Financial sustainability of protected areas is one of the main challenges of management. Financial self-sufficiency is an important element in improving conservation effort in these areas. This study seeks to review best practices in recreational fee systems in different countries and to find a relevant entry fee for a wildlife sanctuary in Malaysia. The revenue of the National Elephant Conservation Center (NECC) in Kuala Gandah, Malaysia, comes from several sources, including the national government, but all these budgetary sources are strained (...) by tighter public budgets and greater demands. The present study investigates the introduction of visitor entrance fees to supplement an otherwise inadequate budget for supporting the operational costs of the sanctuary. Factor analysis and a double-bounded contingent valuation method were combined to estimate tourists' willingness to pay (WTP) the proposed entrance fee. Factor analysis showed that respondents' motivation to support the NECC with user fees is conditioned by their direct experiences with elephants, their satisfaction with NECC's educational programs and services, and other experiences it gives to users. The WTP model considered respondents' four motivation factors with their sociodemographic characteristics. Since NECC visitors arrive from both within and outside the country, this study suggests to center managers a two-tier fee structure (residents vs. nonresidents of Malaysia), based upon mean WTP estimates. This study further suggests that revenue from such an entrance fee for NECC could support the Center's management and development costs. © 2015 Elsevier B. (shrink)

Inevitably, much of this reply will concern points on which I disagree with one or other of the commentators. I should start, therefore, by saying that I am delighted to find that their thinking is in many ways similar to my own, and that a serious attempt is under way to clarify the concept of information in biology.

We introduce a new operator – belief fusion– which aggregates the beliefs of two agents, each informed by a subset of sources ranked by reliability. In the process we definepedigreed belief states, which enrich standard belief states with the source of each piece of information. We note that the fusion operator satisfies the invariants of idempotence, associativity, and commutativity. As a result, it can be iterated without difficulty. We also define belief diffusion; whereas fusion generally produces a belief state with (...) more information than is possessed by either of its two arguments, diffusion produces a state with less information. Fusion and diffusion are symmetric operators, and together define a distributive lattice. Finally, we show that AGM revision can be viewed as fusion between a novice and an expert. (shrink)

The Nuzi Workshop at the 55th Rencontre Assyriologique Internationale. Edited by P. Abrahami and B. Lion. Studies on the Civilization and Culture of Nuzi and the Hurrians, vol. 19. Bethesda: CDL Press, 2012. Pp. xi + 292, illus. $70.

With this treatise, an insightful exploration of the probabilistic connection between philosophy and the history of science, the famous economist breathed new life into studies of both disciplines. Originally published in 1921, this important mathematical work represented a significant contribution to the theory regarding the logical probability of propositions. Keynes effectively dismantled the classical theory of probability, launching what has since been termed the “logical-relationist” theory. In so doing, he explored the logical relationships between classifying a proposition as “highly probable” (...) and as a “justifiable induction.” Unabridged republication of the classic 1921 edition. (shrink)

ObjectivesThe end of life is an ethically challenging time requiring complex decision-making. This study describes ethical frameworks among physician trainees, explores how these frameworks manifest and relates these frameworks to experiences delivering end-of-life care.DesignWe conducted semistructured in-depth exploratory qualitative interviews with physician trainees about experiences of end-of-life care and moral distress. We analysed the interviews using thematic analysis.SettingAcademic teaching hospitals in the United States and United Kingdom.ParticipantsWe interviewed 30 physician trainees. We purposefully sampled across three domains we expected to be (...) associated with individual ethics in order to elicit a diversity of ethical and experiential perspectives.ResultsSome trainees subscribed to a best interest ethical framework, characterised by offering recommendations consistent with the patient’s goals and values, presenting only medically appropriate choices and supporting shared decision-making between the patient/family and medical team. Others endorsed an autonomy framework, characterised by presenting all technologically feasible choices, refraining from offering recommendations and prioritising the voice of patient/family as the decision-maker.ConclusionsThis study describes how physician trainees conceptualise their roles as being rooted in an autonomy or best interest framework. Physician trainees have limited clinical experience and decision-making autonomy and may have ethical frameworks that are dynamic and potentially highly influenced by experiences providing end-of-life care. A better understanding of how individual physicians’ ethical frameworks influences the care they give provides opportunities to improve patient communication and advance the role of shared decision-making to ensure goal-aligned end-of-life care. (shrink)

Richard Levins (1930-2016) was an outstanding ecologist, population geneticist, biomathematician, philosopher of science, complexity theorist, and Marxist. Key to all aspects of his work was a dialectical logic of process and change. His work provides a framework for the understanding of crises in environment and society and their analytic relationship with capitalism and imperialism, as well as the tools for the critique of biological determinist justifications for the existing structures of power. This anthology pays tribute to Levins by carrying forward (...) his work in the development of the understanding of the dialectics of nature and society. -/- The contributions are organized into four sections--Dialectics in Wholistic Research; Political Ecology and Health; Complex Systems; and Reminiscences and Tributes. The authors are as almost as hard to label as Levins; the fields they draw from range from biomathematics to NGO activism; environmental policy to island and aquatic ecology; eco-justice podcasting to biogeochemistry; reflective practice to science-in-society, agroecology to public health. (shrink)

A slew of recent political theorists—many taking their cue from the political writings of Bernard Williams—have recently contended that political normativity is its own kind of normativity, distinct from moral normativity. In this article, we first attempt to clarify what this claim amounts to and then reconstruct and interrogate five major arguments for it. We contend that all these arguments are unconvincing and fail to establish a sense in which political normativity is genuinely separate from morality.

There are continual “crises” in health care systems worldwide as producer and patient groups unify and decry the “underfunding” of health care. Sometimes this cacophony is the self interest of profit seeking producers and often it is advocacy of unproven therapies. Such pressure is to be expected and needs careful management by explicit rationing criteria which determine who gets access to what health care. Science and rationality, however, are unfortunately, rarely the rules of conduct in the medical market-place.

Arien Mack and Irvin Rock make the radical claim that there is no conscious perception of the visual world without attention to it.

Incidental findings in research with human participants may have implications for a person’s present health or future health outcomes. Current guidelines focus on methods for handling and reporting incidental findings from biological test data but incidental findings might also arise from non-biological tests. This article presents three examples in which the results from non-biological test data can be predictive of future disease and should be disclosed to research participants. It is intended to increase awareness and facilitate further discussion about the (...) reporting of incidental findings from non-biological data. (shrink)

The question of what constitutes a finished work is thrown open, reminding us that in certain of his completed autographs Beethoven continued the process that he normally reserved for the earlier stages of composition, setting out further choices, possibilities, and interchangeabilities, including radical alterations in goal as well as detail. In particular, the revision of movement endings was one of his long-standing preoccupations. In works of his middle period, Emil Platen observed, Beethoven continued to make essential alterations in the closing (...) sections of movements after the works had already taken concrete notational form; for example, in the scores of the String Quartets, op. 59, “out of a total of seven movement endings, six were altered after the fact, four in essential ways.”6 Indeed the relationship between sketches and compositional goals was always more problematical than traditional scholars were willing to allow. As Lewish Lockwood has shown, the closer one looks at the sketches the less one can continue to accept as an article of faith that “as a work progresses from first inklings to final realization it should pass through successive phases of growth and clarification of structure, and of complication of detail in relation to that structure, becoming progressively more definite en route to its goal.”7 To further thicken the issue, Janet Levy has pointed out that one “cannot assume that the goals of a completed work are necessarily the same as the goals of the sketches for it,” inasmuch as the composer’s intentions may well have changed during the course of composition and we may be left with sketches made in connection with goals no longer reflected in the final work.8 Composition is only partly a teleological process whereby the composer eventually finds a lapidary form for a predetermined idea. With Beethoven, not only is there no prospective inevitability, there may even be no inevitability after the fact. His sketches and autographs may well be series of rough maps to the multiplicity of universes he glimpsed, to a plurality of possibilities, a jammed crossroads of paths taken and not taken. 6. Emil Platen, “Beethovens Autographen als Ausgangspunkt morphologischer Untersuchungen,” in Bericht über den internationalen musikwissenschaftlichen Kongress: Bonn 1970, ed. Carl Dahlhaus et al. , p. 535. See also Lewis Lockwood, “Beethoven and the Problem of Closure: Some Examples from the Middle-Period Chamber Music,” in Beiträge zu Beethovens Kammermusik, p. 270.7. Lockwood, “On Beethoven’s Sketches and Autographs: Some Problems of Definition and Interpretation,” Acta Musicologica 42 : 34.8. Levy, Beethoven’s Compositional Choices, p. 3. Maynard Solomon’s books include Beethoven , Beethoven Essays , and, most recently, Beethoven’s Tagebuch . He has also written on Schubert, Ives, and Freud, and has edited a standard work on Marxist aesthetics. He is currently writing a life of Mozart and a study of the origins of music. In 1990 he was visiting professor of music at Columbia University. (shrink)