The aim of this paper is to present the modes of action of venom as construed by Abū 'Uthmān 'Amr ibn Ba[hdotu]r al-Jā[hdotu]i[zdotu] in his Kitāb al-[Hdotu]ayawān. The toxicological information presented by Jā[hdotu]i[zdotu] is a synthesis of data available in his time, but Jā[hdotu]i[zdotu] complemented these early conceptions by his personal theoretical views. Jā[hdotu]i[zdotu]'s fundamental idea is that venoms act through their specific natures; this idea in a way is reminiscent of present-day theory of enzymes.

RésuméLe but de cet article est de présenter un rapport d'origine arabe médiévale concernant six animaux du Golfe d'Aden, de fournir une identification zoologique des cinq parmi ces animaux qui peuvent être identifiés, et d'analyser les informations biologiques fournies par ce rapport à la lumière des connaissances zoologiques à la fois contemporaines au rapport et modernes, afin d'évaluer ainsi le niveau scientifique de celui-ci.

Les oeuvres de Gersonide (Levi b. Gershom ou Gerson, Leon de Bagnols, philosophe juif provencal 1288-1344) portent essentiellement sur quatre domaines: les commentaires qu'il a consacres aux commentaires d'Averroes, les questions philosophiques et theologico-philosophiques (livres I a IV, VI des Guerres du Seigneur), les commentaires biblioques et des travaux astronomiques (dont le livre V des Guerres). Dans les trois premiers domaines, la maniere dont il a travaille, l'ordonnancement des idees et leur mise en oeuvre sont ici compares a ceux qui (...) furent utilises par ses contemporains scolastiques. Alors que son activite astronomique a amene Gersonide a la frequentation des savants de la cour du Pape a Avignon, il ne cite, dans les oeuvres etudiees, aucun auteur ni aucun texte latin. La maniere dont Gersonide fait de la philosophie, sa methode d'etude et de resolution des problemes, sa conception de l'exegese biblioque comme science et les procedes adoptes dans les commentaires bibliques le rapprochent cependant du monde latin intellectuel de son temps. Ce sont ces ressemblances, mais aussi les dissemblances, qui sont discutees ici. (shrink)

Newly edited by Konrad Koerner (University of Ottawa), with an introduction by Clemens Knobloch (Universitat Siegen)The importance of Wegener's Untersuchungen uber die Grundfragen des Sprachlebens can only be compared to that of Karl Buhler's Sprachtheorie. Even now, however, Wegener's work remains virtually unknown to the English speaking world. Wegener's main work was published in 1885. It has its origin in two lectures given in 1883 and 1884 at school teacher meetings held in the Magdeburg area and it still recalls those (...) original occasions and maintains much of the oral style. Part of the volume treats the subject in a systematic and theoretical manner; other sections contain vivid examples and are characterized by a considerable didactic effort. The book is held together by leitmotif-questions, such as 'How do we understand language?' and 'How does language function as a means of everyday communication?'. We witness the experiences of the talented school teacher and the observations of the innovative dialect researcher combined, condensed, and conceptually ordered.In spite of the relatively unsystematic form of presentation, the book remains thoroughly consistent in thought and argument. In the Untersuchungen we have before us the outline of a communicative and functional view of language structure, of the analysis of speech, and of semantics. (shrink)

2020 CHOICE Outstanding Academic Title In this book, Philipp von Wussow argues that the philosophical project of Leo Strauss must be located in the intersection of culture, religion, and the political. Based on archival research on the philosophy of Strauss, von Wussow provides in-depth interpretations of key texts and their larger theoretical contexts. Presenting the necessary background in German-Jewish philosophy of the interwar period, von Wussow then offers detailed accounts and comprehensive interpretations of Strauss's early masterwork, Philosophy and Law, his (...) wartime lecture "German Nihilism," the sources and the scope of Strauss's critique of modern "relativism," and a close commentary on the late text "Jerusalem and Athens." With its rare blend of close reading and larger perspectives, this book is valuable for students of political philosophy, continental thought, and twentieth-century Jewish philosophy alike. It is indispensable as a guide to Strauss's philosophical project, as well as to some of the most intricate details of his writings. (shrink)

This study aims at justifying one of Gilbert Durand’s postulates according to which all imaginaire (as a result of mental imagery) is anchored in our physiology but by directing it rather now towards our neurophysiology. New advances in neurobiology, connectome and neurogenomics lead to rethinking the framework of psychic activity and the induction of neural images.

La naissance du CRI à Grenoble doit être replacée dans le contexte intellectuel de la nouvelle critique des années 1960. Les trois courants dominants du matérialisme historique, de la psychanalyse freudienne et du structuralisme ont alors été dépassés par le CRI au profit d’un « nouvel esprit anthropologique » qui privilégiait la réalité sensible des images au détriment des idéologies réductrices. Les intellectuels des villes ont perdu le lien charnel avec une civilisation rurale et un mode de vie ayant façonné (...) notre langue, nos croyances et nos fêtes, ainsi que des artisanats séculaires. Le médiéviste peut encore retrouver le lien avec cette mémoire du temps. Mais s’il n’a pas conservé une âme païenne et un esprit paysan, il est condamné à la posture post-moderne. Penser la culture occidentale en contournant ou ignorant le Moyen Âge n’est qu’une imposture. Un exemple de longue vie des images montre l’importance des relais culturels qui relativise toute théorie préconçue des archétypes. The birth of the CRI in Grenoble is replaced in the intellectual context of new criticism of the 1960s. The three mainstream have been overtaken by the CRI in favour of a “new anthropological spirit” that emphasizes the sensible reality of images at the expense of reducing ideologies. The modern scholars of the cities have lost the carnal connection with a rural civilization and a way of life that have shaped our language, our ancient beliefs and feasts and also centuries-old handicrafts. The medievalist can find the link with this memory of time. But if he has lost a pagan soul and a spirit of peasant, he is sentenced to a post-modern posture. Thinking Western culture in bypassing or ignoring the middle ages appears like a mere sham. An example of long-life images stresses the importance of cultural relays against all preconceived theory of the archetypes. (shrink)

Cet article a pour but de faire connaître au lecture une approche théorique de la réalité physique différente de celle communément admise depuis les débuts de la science physique. On y montre d'abord comment l'approche traditionnelle traite avec une notion de l'événement physique et des étres physiques en ǵenéral qui laisse systématiquement de côté ces éléments de complexité considérés trop facilement comme superflus, mais qui appartiennent à la réalité physique et en constituent la trame. On proposera alors une nouvelle approche (...) qui s'avérera complémentaire de l'approche traditionnelle, en mettant en jeu la notion d'événement singulier, caractérisé par son unicité dans l'espace-temps tout comme un fait historique muni de toute sa richesse factuelle qui est la base de son individualité. (shrink)

Un survol historique des principales conceptions du fatalisme dans l’histoire sert ici de fil conducteur pour envisager le dépassement possible d’une conception fataliste qui caractériserait la pensée moderne dans son ensemble, et par conséquent le dépassement de la notion de liberté qu’on peut lui associer. Ce fatalisme moderne est celui que l’on peut attacher à la conception moderne de l’histoire, ce mot - histoire - étant entendu non comme la suite accidentelle des faits par opposition à une raison objective, mais (...) comme l’horizon même, explicite ou implicite, de l’ensemble de la conceptualisation rationnelle moderne. Il s’agit donc, ici, de considérer la possibilité d’un dépassement de cet horizon généralement tenu pour ultime et du type de fatalisme qui lui correspond.A historical survey of the main conceptions of fatalism is made. This serve us as a guide in order to conceive a mean for going beyond a conception of fatalism which seems to be typical of modern thought as a whole. Accordingly this can permit us to go beyond an idea of liberty which is linked to it. We can attach this modern fatalism to the modern conception of history, where we understand this word - history - not as an accidental succession of facts as opposed to an objective reason, but as the explicit or implicit horizon itself of the modern rational conceptualisation as a whole. Therefore we are concerned here about the possibility to go beyond this horizon which is generally considered as ultimate, and beyond the kind of fatalism which corresponds to it. (shrink)

In light of its history of interpretation, an interpretive essay on the fifth book of Plato's Republic is advanced, on the premise that existing views of the relation of Book V to the rest of the dialogue are inadequate. The metaphor of the "three waves" indicates more than a mere formal unity to the argument of Book V, since the logic of the first two "waves" only becomes evident in light of their dependence upon the logic of the third "wave" (...) . The "three waves" constitute a single, unified argument, which discloses the dependence of justice, as defined in terms of the state and individual in Book IV, upon the idea of the good set forth in Book VI. (shrink)

The ?language of the gods? is conceived as a kind of language more complex than what we associate with human tongues in the strict sense of the term. Certain arbitrary regularities throughout the rational disciplines appear to indicate the existence of this language. The present article explores this new concept and applies it in an attempt to provide a logical clarification of the notions of individual consciousness and physical reality.

La notion d'objectivité fait l'objet d'une étude qui s'inscrit dans une visée globale, ce qui doit s'entendre dans le sens d'une globalité des savoirs rationnels, auxquels on tente ici d'assigner des ordres d'objectivité, et dans le sens d'une globalité historique, où il est envisagé de faire correspondre ces ordres d'objectivité à quelques grandes époques de l'histoire de la pensée rationnelle depuis l'Antiquité. On se penchera notamment sur la signification profonde des rapports intersubjectifs dans les constitutions objectives. Une clarification de la (...) signification de l'induction dans les sciences expérimentales pourra en résulter.We examine the notion of objectivity in a global aim, i.e. along the line of the main types of rational knowledges and along the line of the history since the Antiquity. We develop the idea of many orders of objectivity each of which corresponding to types of knowledge and to great periods in the history of rational thinking. In particular we attempt to consider the deep significance of intersubjectivity in relation to objectivity. As a result the significance of the induction in the experimental sciences should become clearer. (shrink)

This is a study that investigated the extent of use of the three principles of ethics – utility, morality, and justice – in managerial ethical decision making, in addition to the personal attitude towards them. It involved undergraduate and graduate business students (total N=163) from the Olayan School of Business in the American University of Beirut, Lebanon. Two kinds of measurements were done: self assessment, and testing with the Saschkin’ s Managerial Value Profile (1997). It showed that morality was the (...) overriding ethical principle used, especially in the graduate group (professionals). Business students still believed in the justice system despite the weakness of the country’s law. Utility was the least used, although males were found to be more utilitarian than females. Finally there was no relation between personal attitudes toward the three ethical principles, and the intentional behavior when faced with ethical dilemmas. The findings were discussed and recommendations were given. (shrink)

There are various conceptions of objectivity, a characteristic of the scientific enterprise, the most fundamental being objectivity as faithfulness to facts. A brute fact, which happens independently from us, becomes a scientific fact once we take cognisance of it through the means made available to us by science. Because of the complex, reciprocal relationship between scientific facts and scientific theory, the concept of objectivity as faithfulness to facts does not hold in the strict sense of an aperspectival faithfulness to brute (...) facts. Nevertheless, it holds in the large sense of an underdetermined faithfulness to scientific facts, as long as we keep in mind the complexity of the notion of scientific fact (as theory-laden), and the role of non-factual elements in theory choice (as underdetermined by facts). Science remains our best way to separate our factual beliefs from our other kinds of beliefs. (shrink)

We have entered a new long-term war regime. This regime is multiform, and deployed on two mutually interpenetrating fronts: one internal, the other external. The military and the forces of a law and order » cooperate with each other to face a supposed common enemy: international terrorism, both actual and potential. If, in this war regime, the American government occupies a leadership position, several other governments are engaged at the sane level, France and Russia amongst them. This state of affairs (...) cannot be reduced to a simple model of American imperialism. This article argues that the principal cause is at once the deepest and largest: it reflects the fear of globality, of the subversive emergence of a humanity at once globalised and mixed, which in multiple ways, shifts future prospects: shaking up dominations, confronting the big, global problems, without playing the game of conflicts of force and territory. It is this, fear which, whilst it motivates those promoting this new regime, also poses to us, a real challenge: that of expressing, more than they can suppress, the virtualities of this globality. (shrink)

This paper concerns Aristotle's kind‐crossing prohibition. My aim is twofold. I argue that the traditional accounts of the prohibition are subject to serious internal difficulties and should be questioned. According to these accounts, Aristotle's prohibition is based on the individuation of scientific disciplines and the general kind that a discipline is about, and it says that scientific demonstrations must not cross from one discipline, and corresponding kind, to another. I propose a very different account of the prohibition. The prohibition is (...) based on Aristotle's scientific and metaphysical essentialism, according to which a scientific demonstration must take as its starting point a set of per se properties of a subject, if these make up a single, unitary definition. The subject of demonstration here is a kind, although not the general kind associated with a discipline, but rather the particular kind that the particular demonstration is about. (shrink)

Kaplan claims in Demonstratives that no operator may manipulate the context of evaluation of natural language indexicals. We show that this is not so. In fact, attitude reports always manipulate a context parameter (or, rather, a context variable). This is shown by (i) the existence of De Se readings of attitude reports in English (which Kaplan has no account for), and (ii) the existence of a variety of indexicals across languages whose point of evaluation can be shifted, but only in (...) attitude reports. We develop an alternative account within an extensional framework with overt quantification over times, worlds and contexts. Various typological facts are discussed, esp. the distinction between English, Amharic and Ewe pronouns, and that between English and Russian tenses. (shrink)

According to one productive and influential approach to cognition, categorization, object recognition, and higher level cognitive processes operate on a set of fixed features, which are the output of lower level perceptual processes. In many situations, however, it is the higher level cognitive process being executed that influences the lower level features that are created. Rather than viewing the repertoire of features as being fixed by low-level processes, we present a theory in which people create features to subserve the representation (...) and categorization of objects. Two types of category learning should be distinguished. Fixed space category learning occurs when new categorizations are representable with the available feature set. Flexible space category learning occurs when new categorizations cannot be represented with the features available. Whether fixed or flexible, learning depends on the featural contrasts and similarities between the new category to be represented and the individual's existing concepts. Fixed feature approaches face one of two problems with tasks that call for new features: If the fixed features are fairly high level and directly useful for categorization, then they will not be flexible enough to represent all objects that might be relevant for a new task. If the fixed features are small, subsymbolic fragments (such as pixels), then regularities at the level of the functional features required to accomplish categorizations will not be captured by these primitives. We present evidence of flexible perceptual changes arising from category learning and theoretical arguments for the importance of this flexibility. We describe conditions that promote feature creation and argue against interpreting them in terms of fixed features. Finally, we discuss the implications of functional features for object categorization, conceptual development, chunking, constructive induction, and formal models of dimensionality reduction. Key Words: concept learning; conceptual development; features; perceptual learning; stimulus encoding. (shrink)

This article discusses Sven Ove Hansson’s corpus model for the influence of values (in particular, non-epistemic ones) in the hypothesis acceptance/rejection phase of scientific inquiry. This corpus model is based on Hansson’s concepts of scientific corpus and science ‘in the large sense’. I first present Hansson’s corpus model of value influence with some introductory comments about its origins, a detailed presentation of the model with a new terminology, an analysis of its limits, and an appreciation of its handling of controversial (...) non-epistemic values. I conclude that it is a very good candidate for managing value influence, because contrary to other models in the literature it is fairly simple, it provides a universal and systematic procedure for dealing with values, and it syste- matically preserves the epistemic integrity of science. I then study some difficulties associated with the model’s central feature of taking the maximum level of evidence required by the applications of a claim in order for the latter to enter the scientific corpus: the difficulty to identify this maximum requirement; the non-optimality of this requirement with respect to other less demanding requirements; the potentially detrimental consequences of the preference for false negatives over false positives on which it relies; and the issue of whether there can nevertheless be requirements higher than this maximum. I show that these issues may potentially challenge the corpus model. Finally, I call for empirical work (in particular, an investigation of scientists’ and engineers’ own normative views) in order to better assess these issues. (shrink)

Polysemous concepts with multiple related meanings pervade natural languages, yet some philosophers argue that we should eliminate them to avoid miscommunication and pointless debates in scientific discourse. This paper defends the legitimacy of polysemous concepts in science against this eliminativist challenge. My approach analyses such concepts as patchworks with multiple scale-dependent, technique-involving, domain-specific and property-targeting uses (patches). I demonstrate the generality of my approach by applying it to "hardness" in materials science, "homology" in evolutionary biology, "gold" in chemistry and "cortical (...) column" in neuroscience. Such patchwork concepts are legitimate if the techniques used to apply them produce reliable results, the domains to which they are applied are homogenous, and the properties they refer to are significant to describe, classify or explain the behavior of entities in the extension of the concept. By following these normative constraints, researchers can avoid miscommunication and pointless debates without having to eliminate polysemous patchwork concepts in scientific discourse. (shrink)

ABSTRACTWhat is the relation between ethical reflection and moral behavior? Does professional reflection on ethical issues positively impact moral behaviors? To address these questions, Schwitzgebel and Rust empirically investigated if philosophy professors engaged with ethics on a professional basis behave any morally better or, at least, more consistently with their expressed values than do non-ethicist professors. Findings from their original US-based sample indicated that neither is the case, suggesting that there is no positive influence of ethical reflection on moral action. (...) In the study at hand, we attempted to cross-validate this pattern of results in the German-speaking countries and surveyed 417 professors using a replication-extension research design. Our results indicate a successful replication of the original effect that ethicists do not behave any morally better compared to other academics across the vast majority of normative issues. Yet, unlike the original study, we found mixed results o... (shrink)

This article explores the question of how to understand social media following the Habermasian theory of the structural transformation of the public sphere. We argue for a return to political-economic fundamentals as the basis for analysing the public sphere and seek to establish a characteristic connection between digital-behavioural control and singularised audiences in the context of proprietary markets. In the digital constellation, it is less a matter of immobilising the citizen as a consumer but rather of their political activation – (...) albeit in conditions under which commercial interests have primacy: privatisation without privatism. (shrink)

The focus of this paper are the ethical, legal and social challenges for ensuring the responsible use of “big brain data”—the recording, collection and analysis of individuals’ brain data on a large scale with clinical and consumer-directed neurotechnological devices. First, I highlight the benefits of big data and machine learning analytics in neuroscience for basic and translational research. Then, I describe some of the technological, social and psychological barriers for securing brain data from unwarranted access. In this context, I then (...) examine ways in which safeguards at the hardware and software level, as well as increasing “data literacy” in society, may enhance the security of neurotechnological devices and protect the privacy of personal brain data. Regarding ethical and legal ramifications of big brain data, I first discuss effects on the autonomy, the sense of agency and authenticity, as well as the self that may result from the interaction between users and intelligent, particularly closed-loop, neurotechnological devices. I then discuss the impact of the “datafication” in basic and clinical neuroscience research on the just distribution of resources and access to these transformative technologies. In the legal realm, I examine possible legal consequences that arises from the increasing abilities to decode brain states and their corresponding subjective phenomenological experiences on the hitherto inaccessible privacy of these information. Finally, I discuss the implications of big brain data for national and international regulatory policies and models of good data governance. (shrink)

: In the 1980s, the analysis of presupposition projection contributed to a ‘dynamic turn’ in semantics: the classical notion of meanings as truth conditions was replaced with a dynamic notion of meanings as Context Change Potentials. We argue that this move was misguided, and we offer an alternative in which presupposition projection follows from the combination of a fully classical semantics and a new pragmatic principle, which we call Be Articulate. This principle requires that a meaning pp’ conceptualized as involving (...) a pre-condition p should be articulated as … … rather than as … pp’ …, unless the full conjunction is ruled out because the first or the second conjunct is semantically idle. In particular, … … is infelicitous - and hence … pp’ … is acceptable - if one can determine as soon as p and is uttered that no matter how the sentence ends these words could be eliminated without affecting its contextual meaning. An equivalence theorem guarantees that this condition suffices to derive Heim’s results in almost all cases. Extensions of the condition lead to several new predictions, in particular concerning some ‘symmetric readings’, as well as presupposition projection in quantified structures, which displays a complex interaction between the nature of the trigger and the monotonicity of the quantifier. (shrink)

Developing tools is a crucial aspect of experimental practice, yet most discussions of scientific change traditionally emphasize theoretical over technological change. To elaborate on the role of tools in scientific change, I offer an account that shows how scientists use tools in exploratory experiments to form novel concepts. I apply this account to two cases in neuroscience and show how tool development and concept formation are often intertwined in episodes of tool-driven change. I support this view by proposing common normative (...) principles that specify when exploratory concept formation and tool development succeed to initiate scientific change. (shrink)

Animal research suggests that central serotonergic neurons are involved in behavioral suppression, particularly anxiety-related inhibition. The hypothesis linking decreased serotonin transmission to reduced anxiety as the mechanism in the anxiolytic activity of benzodiazepines conflicts with most clinical observations. Serotonin antagonists show no marked capacity to alleviate anxiety. On the other hand, clinical signs of reduced serotonergic transmission (low 5-HIAA levels in the cerebrospinal fluid) are frequently associated with aggressiveness, suicide attempts, and increased anxiety. The target article attempts to reconcile such (...) human and animal findings by investigating whether anxiety reduction or increased impulsivity is more Likely to account for animal behavioral changes associated with decreased serotonergic transmission. The effects of manipulating central serotonin in experimental anxiety paradigms in animals (punishment, extinction, novelty) are reviewed and compared with the effects of antianxiety drugs. Anxiety seems neither necessary nor sufficient to induce control by serotonergic neurons on behavior. Further evidence suggests that behavioral effects of anxiolytics thought to be mediated by decreases in anxiety are not caused by the ability of these drugs to reduce serotonin transmission. Blockade of serotonin transmission, especially at the level of the substantia nigra, results in a shift of behavior toward facilitation of responding. This behavioral shift is particularly marked when there is competition between acting and restraining response tendencies and when obstacles prevent the immediate attainment of an anticipated reward. It is proposed that serotonergic neurons are involved not only in behavioral arousal but also in enabling the organism to arrange or tolerate delay before acting. Decreases in serotonin transmission seem to be associated with the increased performance of behaviors that are usually suppressed, though not necessarily because of the alleviation of anxiety, which might contribute to the suppression. (shrink)

First, the demonstration of Bell's theorem, i.e., of the nonlocal character of quantum theory, is spelled out using the EPR criterion of reality as premises and a gedankenexperiment involving two particles. Then, the EPR criterion is extended to include quantities predicted almostwith certainty, and Bell's theorem is demonstrated on these new premises. The same experiment is used but in conditions that become possible in real life, without the requirements of ideal efficiencies and zero background. Very high efficiencies and low background (...) are needed, but these requirements may be met in the future. (shrink)