Background Sharing of genomic data aims to make efficient use of limited resources, which may be particularly valuable in rare disease research. Adult research participants and parents of pediatric research participants have shown support for data sharing with protections, but little is known about adolescent attitudes on genomic privacy and data sharing.Methods In-depth interviews were conducted with 10 adolescents and 18 parents of children enrolled in a pediatric genomic research repository. Interview transcripts were analyzed for themes on attitudes toward genomic (...) privacy, restricted-access data sharing, and open-access data sharing. Findings in adolescent and parent participants were compared and contrasted.Results No adolescents endorsed privacy concerns for restricted-access data sharing. Both adolescents and parents saw value in data sharing for reaching the goals of research and discussed trust in institutions and researchers to protect their data and use it as intended. Adolescents were more likely than parents to accept open-access data sharing, including after risks were discussed.Conclusions In this exploratory study, adolescents and parents enrolled in a genomic research repository shared many attitudes about genomic data sharing, but adolescents were less concerned about privacy and more agreeable toward open-access data sharing. Future research is needed to investigate this hypothesis in expanded populations and settings, and to clarify whether adolescent attitudes change with age and experiences. (shrink)

I reply to Mills's critique of my effort to show the relevance of Rawls's theory of justice for thinking about and responding to racial injustices. Contrary to Mills's claims, my suggestion that the fair equality of opportunity principle can remedy socioeconomic disadvantages caused by the legacy of racial oppression is compatible with Rawls's framework, does not conflate distributive justice with corrective justice, and does not confuse racial injustice with economic injustice. I also raise doubts about Mills's project to radically reconstruct (...) contractarian political philosophy. He seeks to displace ideal theory with nonideal theory by foregrounding the realities of past racial domination. Against this approach, I argue that an ideal theory that abstracts away from these realities is not inherently ideological, useless for corrective justice, or too ideal to guide social reform. And I defend the view that ideal theory is indispensible for nonideal theorizing about racial justice. (shrink)

In this chapter I articulate the threat that time travel to the past allegedly poses to the free will of the time traveler, and I argue that on the traditional way of thinking about free will, the incompatibilist about time travel and free will wins the day. However, a residual worry about the incompatibilist view points the way toward a novel way of thinking about free will, one that I tentatively explore toward the end of the chapter.

In this paper I argue that adopting a perdurance view of persistence through time does not lead to skepticism about moral responsibility, despite what many theorists have thought.

This chapter explores the concept of judgmentalism: what it is and why it’s morally problematic. After criticizing an account offered by Gary Watson, the paper argues for a broader understanding of what it is to be judgmental, encompassing not just the overall beliefs that we form about someone else, but also the very pattern of our thoughts about those with whom we are involved in interpersonal relationships. The thesis is that to care about someone is to be oriented toward them, (...) or to see them through a particular mental lens, in a way that produces a particular pattern of salience and silence. That is: caring about someone (at least ideally) has the effect of making some features of that person particularly salient, and silencing or screening off other features from one’s consciousness. One is aptly described as judgmental when one’s thoughts do not display this sort of pattern, indicating a failure to fully adopt the orientation that constitutes properly caring about the person. (shrink)

Although the character of the “lady detective”is a staple of the cozy mystery genre, we contend that there are no great lady detectives to rival Holmes or Poirot. This is not because there are no clever or interesting lady detective characters, but ratherbecause the concept of greatness is sociallyconstructed and, like coolness, depends on public acclaim and perception. We explore the mechanics of genre formation, arguing that the very structure of cozy mysteries precludes female greatness. To create a “great”character,theauthor cannot (...) just endowher with certain attributes; she must actively work to overcome her audience’s tendency to import structures of oppression into the story, and she must wrestle against the conventions of the genre. In doing so, however, authors risk setting their stories in a wholly different genre. (shrink)

Names, descriptions, and demonstratives raise well-known logical, ontological, and epistemological problems. Perhaps less well known, amongst philosophers at least, are the ways in which some of these problems not only recur with pronouns but also cross-cut further problems exposed by the study in generative linguistics of morpho-syntactic constraints on interpretation. These problems will be my primary concern here, but I want to address them within a general picture of interpretation that is required if wires are not to be crossed. That (...) picture will be sketched in sections 3 and 4; subsequent sections will focus on pronouns and binding, drawing heavily on what has preceded. (shrink)

African American history resounds with calls for black unity. From abolitionist times through the Black Power movement, it was widely seen as a means of securing a full share of America's promised freedom and equality. Yet today, many believe that black solidarity is unnecessary, irrational, rooted in the illusion of "racial" difference, at odds with the goal of integration, and incompatible with liberal ideals and American democracy. A response to such critics, We Who Are Dark provides the first extended philosophical (...) defense of black political solidarity. Tommie Shelby argues that we can reject a biological idea of race and agree with many criticisms of identity politics yet still view black political solidarity as a needed emancipatory tool. In developing his defense of black solidarity, he draws on the history of black political thought, focusing on the canonical figures of Martin R. Delany and W. E. B. Du Bois, and he urges us to rethink many traditional conceptions of what black unity should entail. In this way, he contributes significantly to the larger effort to re-envision black politics and to modernize the objectives and strategies of black freedom struggles for the post-civil rights era. His book articulates a new African American political philosophy--one that rests firmly on anti-essentialist foundations and, at the same time, urges a commitment to defeating racism, to eliminating racial inequality, and to improving the opportunities of those racialized as "black.". (shrink)

A crucial design feature of language useful for determining when grammatical language evolved in the human lineage is our ability to combine meaningless units to form a new unit with meaning (combinatoriality) and to further combine these meaningful units into a larger unit with a novel meaning (compositionality). There is overlap between neural bases that underlie hierarchical cognitive functions required for compositionality in both linguistic and nonlinguistic contexts (e.g., tool use). Therefore, evidence of compositional tool use in the archaeological record (...) should signify, at the very least, the cognitive capacity for grammatical language by that point in time. We devise a novel system to evaluate the level of hierarchical nesting of tool components in single tool use activities. In the application of this system, we demonstrate that nonhuman primates, and by extension, the last common ancestor shared by Pan and Homo, are capable of basic combinatoriality; however, their technology does not approach the compositionality observable in modern human tool use. The prehistoric archaeological record supports a continuous evolution of combinatorial tool use into compositional tool use, with evidence for human-like levels of by 0.93 million years ago (Ma), or possibly as early as 1.7 Ma. While compositional language could have lagged behind compositional tool use, if language and technology coevolved according to the Technological Origin for Language hypothesis, which proposes a feedback system between the two, then evidence for hierarchical tool use structures implies a similar level of complexity in linguistic structures. (shrink)

In this study, we test the interactive effect on ethical decision-making of (1) personal characteristics, and (2) personal expectanciesbased on perceptions of organizational rewards and punishments. Personal characteristics studied were cognitive moral developmentand belief in a just world. Using an in-basket simulation, we found that exposure to reward system information influenced managers’ outcome expectancies. Further, outcome expectancies and belief in a just world interacted with managers’ cognitive moral development to influence managers’ ethical decision-making. In particular, low-cognitive moral development managers who (...) expected that their organization condoned unethical behavior made less ethical decisions while high cognitive moral development managers became more ethical in this environment. Low cognitive moral development managers also behaved less ethically when their belief in a just world was high. (shrink)

In this study, we test the interactive effect on ethical decision-making of (1) personal characteristics, and (2) personal expectanciesbased on perceptions of organizational rewards and punishments. Personal characteristics studied were cognitive moral developmentand belief in a just world. Using an in-basket simulation, we found that exposure to reward system information influenced managers’ outcome expectancies. Further, outcome expectancies and belief in a just world interacted with managers’ cognitive moral development to influence managers’ ethical decision-making. In particular, low-cognitive moral development managers who (...) expected that their organization condoned unethical behavior made less ethical decisions while high cognitive moral development managers became more ethical in this environment. Low cognitive moral development managers also behaved less ethically when their belief in a just world was high. (shrink)

This article explores whether theory-ladenness makes empirical testing an inse cure foundation for objectivity. Specifically, this article uses path diagrams as visual heuristics to assist in (1) developing a parsimonious representation of the traditional empiricist view of empirical testing, (2) showing how the "New Image" view ostensibly threatens the objectivity of science, (3) proposing a unified, realist theory of empirical testing, (4) developing a representation of the unified theory, (5) exploring several potential threats to objectivity, (6) discussing the proposed theory's (...) implications for social science, and (7) adumbrating three foundational premises for scientific realism. (shrink)

We used optical neuroimaging to explore the extent of functional overlap between working memory (WM) networks involved in language and Early Stone Age toolmaking behaviors. Oldowan tool production activates two verbal WM areas, but the functions of these areas are indistinguishable from general auditory WM, suggesting that the first hominin toolmakers relied on early precursors of verbal WM to make simple flake tools. Early Acheulian toolmaking elicits activity in a region bordering on Broca’s area that is involved in both visual (...) and verbal WM tasks. The sensorimotor and mirror neurons in this area, along with enhancement of general WM capabilities around 1.8 million years ago, may have provided the scaffolding upon which a WM network dedicated to processing exclusively linguistic information could evolve. In the road map going forward, neuro-archaeologists should investigate the trajectory of WM over the course of human evolution to better understand its contribution to language origins. (shrink)

According to pancomputationalism, all physical systems – atoms, rocks, hurricanes, and toasters – perform computations. Pancomputationalism seems to be increasingly popular among some philosophers and physicists. In this paper, we interpret pancomputationalism in terms of computational descriptions of varying strength—computational interpretations of physical microstates and dynamics that vary in their restrictiveness. We distinguish several types of pancomputationalism and identify essential features of the computational descriptions required to support them. By tying various pancomputationalist theses directly to notions of what counts as (...) computation in a physical system, we clarify the meaning, strength, and plausibility of pancomputationalist claims. We show that the force of these claims is diminished when weaknesses in their supporting computational descriptions are laid bare. Specifically, once computation is meaningfully distinguished from ordinary dynamics, the most sensational pancomputationalist claims are unwarranted, whereas the more modest claims offer little more than recognition of causal similarities between physical processes and the most primitive computing processes. (shrink)

Despite a long period of neglect, research on emotion in organizational behavior has developed into a major field over the past 15 years, and is now seen to be part of an affective revolution in the organization sciences. In this article, we review current research on emotion in the organizational behavior field based on five levels of analysis: within person, between persons, dyadic interactions, leadership and teams, and organization-wide. Specific topics we cover include affective events theory, state and trait affect (...) and mood, emotional intelligence, emotional labor, emotional contagion, emotions and leadership, and building a healthy emotional climate. We conclude with suggestions for future research. (shrink)

This paper reports the results of a survey of ethical attitudes, values, and propensities in public sector employees in Australia. It was expected that demographic variables, personal values, and contextual variables at the individual level, and group- and organisational-level values would predict use of formal codes of ethics and ethical tolerance (tolerance of unethical behaviour). Useable data were received from 500 respondents selected at random across public sector organisations in a single Australian state. Results supported the study hypotheses, but indicated (...) that different mechanisms underlie each of the criterion variables. Use of ethical codes was determined primarily on the basis of a perception that others use the code, while ethical tolerance was determined by personal values. At an applied level, the research highlights the need for orgasnizations to establish a critical mass of code users, so that this operates as a normative influence on others in the organization. (shrink)

Participation in experimental studies can be conceptualized as Goffmanian frames, i.e. a set of rules which include the fact the experimenter will be observing participant behavior through (the recording of) the experiment. This study is focused on frame breaches in 16 video- and audio-recorded dyadic conversations taking place in an experimental setting. Our main conclusion is that the experimental frame is conceptualized by participants as including constraints that go beyond non-experimental interactions, and in particular the need to mitigate frame breaches, (...) which are seen as face-threatening. Analyses revealed that participants only broke the research frame after they completed the task they were assigned by the researcher, and that breaches did not necessarily correspond to changes in key. Insights gained in relation to face and mitigation are discussed, as well as the participants’ need to determine their next steps once the research purpose has been perceived complete. (shrink)

In public health research, tracking folk racial categories (in disease risk, etc.) is a double-edged tool. On the one hand, tracking folk racial categories is dangerous because it reinforces a problematic but fairly common belief in biological race essentialism. On the other hand, ignoring racial categories also runs the risk of ignoring very real biological phenomena in which marginalized communities, likely in virtue of their marginalization, are sicker and in need of improved resources. Much of the conversation among epidemiologists and (...) philosophers of medicine concerning the issue of tracking folk racial categories in public health research springs forth from largely black/white binarized health inequities. While health inequities between black and white Americans are certainly a very important topic, I am interested in investigating the complications to this conversation about the potential harms of tracking folk racial categories in public health research generated by the consideration of Indigenous identities in the US—groups whose health inequities are typically tracked based on the folk racial category of “Native American” or “American Indian,” but whose unique identity categories and community membership problematize the current spectrum of approaches to tracking folk racial categories in epidemiologic research. This paper will draw on scholarship by and about Indigenous people in the US context to address an undertheorized facet of the conversations concerning the potential harms of tracking folk racial categories in public health research, including the potential undermining of American Indian sovereignty and Indigenous epistemologies. I will end on some methodological considerations inspired by the inclusion of Indigenous identities in the US in the conversation about tracking folk racial categories in epidemiologic research. (shrink)

Settler colonial imaginaries are constructed through the repeated, intergenerational layering of settler ecologies onto Indigenous ecologies; they result in fortified ignorance of the land, Indigenous peoples, and the networks of relationality and responsibility that sustain co‐flourishing. Kyle Whyte (2018) terms this fortification of settler ignorance vicious sedimentation. In this paper, we argue that Outlaw Country music plays important roles in sedimenting settler imaginaries. We begin by clarifying the epistemic dimensions of vicious sedimentation. We then explore specific cases where Outlaw Country (...) songs function as epistemic scaffolding for maintaining and preserving deeply sedimented settler imaginaries. Finally, we conclude by considering ways of using country music as epistemic scaffolding for constructing resistant epistemologies, through the processes of trickster hermeneutics (Vizenor, 1999) and epistemic chronostratigraphy. (shrink)

Much evidence suggests that, from a young age, humans are able to generalize information learned about a subset of a category to the category itself. Here, we propose that—beyond simply being able to perform such generalizations—people are biased to generalize to categories, such that they routinely make spontaneous, implicit category generalizations from information that licenses such generalizations. To demonstrate the existence of this bias, we asked participants to perform a task in which category generalizations would distract from the main goal (...) of the task, leading to a characteristic pattern of errors. Specifically, participants were asked to memorize two types of novel facts: quantified facts about sets of kind members and generic facts about entire kinds. Moreover, half of the facts concerned properties that are typically generalizable to an animal kind, and half concerned properties that are typically more idiosyncratic. We predicted that—because of the hypothesized bias—participants would spontaneously generalize the quantified facts to the corresponding kinds, and would do so more frequently for the facts about generalizable properties. In turn, these generalizations would lead to a higher rate of quantified-to-generic memory errors for the generalizable properties. The results of four experiments supported this prediction. Moreover, the same generalizable-versus-idiosyncratic difference in memory errors occurred even under cognitive load, which suggests that the hypothesized bias operates unnoticed in the background, requiring few cognitive resources. In sum, this evidence suggests the presence of a powerful bias to draw generalizations about kinds. (shrink)

Despite the frequent interpretation of any Early-Christian-era art that contains both Christian and pagan imagery as being solely Christian in meaning, this paper argues that the identification of these images as being Christian in nature, with the pagan imagery only present as borrowed ideas to support a Christian message, is problematic. By assessing some of the existing scholarship surrounding this topic, I attempt to problematize the assumptions made that lead to these widely-accepted interpretations.

This paper examines how Charlotte Brontë's belief in phrenology influences the narration of her novel Jane Eyre. Phrenology was a nineteenth-century belief that the shape of the skull could give information about a person's temperament. Phrenologists speculated that the brain was split into separate parts, or faculties, that defined the individual's ability to feel a particular emotion. A bump on the skull implied that the faculty underneath that part of the skull was bigger, so the individual was more inclined to (...) feel that emotion. By placing Jane Eyre within the historical context of the rise of phrenology, I explore the ways in which Brontë's phrenological representation of Jane's mind informs and parallels the autodiegetic narration of Jane Eyre. My analysis focuses on moments when Jane draws attention to the fact that she is a first-person narrator telling the story of her own past experiences. I argue that these moments are comparable to those when Jane’s experiencing-self is fractured into phrenological faculties. Concomitantly, I seek to trace how Jane's narration changes as she moves between the locations of Thornfield, the Moor House, and Ferndean. I suggest that the shifts in narration draw attention to these locations as metaphors for varying degrees of restriction on Jane's faculties. Through an application of nineteenth-century psychological studies, I conclude that Brontë uses her narration style to criticize phrenologists who promote an unnaturally restrictive control of the faculties. (shrink)

Why do American ghettos persist? Decades after Moynihan’s report on the black family and the Kerner Commission’s investigations of urban disorders, deeply disadvantaged black communities remain a disturbing reality. Scholars and commentators today often identify some factor―such as single motherhood, joblessness, or violent street crime―as the key to solving the problem and recommend policies accordingly. But, Tommie Shelby argues, these attempts to “fix” ghettos or “help” their poor inhabitants ignore fundamental questions of justice and fail to see the urban (...) poor as moral agents responding to injustice. (shrink)

The concept of approximate truth plays a prominent role in most versions of scientific realism. However, adequately conceptualizing ?approximate truth? has proved challenging. This article argues that the goal of articulating the concept of approximate truth can be advanced by first investigating the processes by which science accords theories the status of accepted or rejected. Accordingly, this article uses a path diagram model as a visual heuristic for the purpose of showing the processes in science that are involved in determining (...) a theory's status. This ?inductive realist? model of theory status then serves as a starting point for explicating an inductive realist view of approximate truth that, it is argued, can explain instances of the success of science, but does not (1) require science's theories to be strictly true in any world or (2) require a metric for measuring how close an approximately true theory is to some strictly true theory. To show the advantages of the inductive realist approach to approximate truth, an example of a major success story of science, the successful eradication of smallpox, is reviewed and then explained. (shrink)

1. Metaphysics -- 2. The mind -- 3. Desire and emotion -- 4. Freedom from bondage -- 5. Transcendence.

In 1999, Neale Donald Walsch wrote three little books, each focusing on different areas of life: Neale Donald Walsch on Relationships, Neale Donald Walsch on Holistic Living, and Neale Donald Walsch on Abundance and Right Livelihood. In 2010, these three books were published in a single volume as Neale Donald Walsch's Little Book of Life. Walsch describes this book as a thousand pages of dialogue in the Conversations with God series reduced down to a few salient points and a few (...) very direct observations about how to render them functional. Readers can think of this book as either Conversations with God in a Nutshell or the Essential Conversations with God. Here are the basic principles for: Satisfying personal relationships; Living a joyful, harmonious life; Discovering authentic prosperity. Walsch's words provide hope and help for readers living in particularly challenging times. This is indeed Walsch's essential life guide for twenty-first century readers."--Back cover. (shrink)

CRISPR keeps me up at night. I marvel at its potential to cure insidious genetic diseases and scourges like malaria. I shudder at the ways it might be misused to create biological weapons. What frightens me most, though, is what I can't predict: how will we use CRISPR? How will it change evolution? How will it redefine the very nature of our existence?CRISPR is an ingenious cut-and-paste system that homes in on a particular DNA gene sequence and then, using Cas9 (...) enzymes, snips it out. That sequence is then replaced with a new one that rewrites or repairs the original. Two different cells—somatic, from the body, and germline, from gametes—can be manipulated... (shrink)

Comprising eight revised essays and seven new pieces, this work provides a comprehensive resource for students, scientists, bioethicists, physicians, and laypeople to better understand and discuss the ethical issues underlying this technology that has the potential to forever change the world.

Scholars in language and social interaction have long been concerned with the role of texts in institutional settings, studying, for example, how interview schedules actively shape conversational dynamics between participants. While texts have been acknowledged as active in this way, their generative capacity remains largely overlooked. This article argues that like human subjects, texts in interaction enact agency. One text in particular, a screening form used to diagnose the learning disability attention deficit/hyperactivity disorder, is analyzed to claim that this text (...) brings about the very condition it is designed to measure: a learning disability. Drawing from work in discursive psychology, I show how the measurement requires the client to adopt certain speaking positions, which then enables the text to speak for the client. I also demonstrate how the text constructs otherwise normal behavior as pathological through punctuation and nominalization. Finally, I illustrate how the spatial organization of the text constrains clients’ choices for interacting with it. This article claims that texts produce, rather than reflect, cognitive phenomena, and it moreover encourages that the notion of text as agent be taken seriously, especially when it presents the capacity to disable. (shrink)

Cancer and its treatment pose challenges that affect not only patients but also their significant others, including intimate partners. Accumulating evidence suggests that couples’ ability to communicate effectively plays a major role in the psychological adjustment of both individuals and the quality of their relationship. Two key conceptual models have been proposed to account for how couple communication impacts psychological and relationship adjustment: the social-cognitive processing (SCP) model and the relationship intimacy (RI) model. These models posit different mechanisms and outcomes, (...) and thus have different implications for intervention. The purpose of this project is to test and compare the utility of these models using comprehensive and methodologically rigorous methods. Aims are: (1) to examine the overall fit of the SCP and RI models in explaining patient and partner psychological and relationship adjustment as they occur on a day-to-day basis and over the course of 1 year; (2) to examine the fit of the models for different subgroups (males vs. females, and patients vs. partners); and (3) to examine the utility of various methods of assessing communication by examining the degree to which baseline indices from different measurement strategies predict self-reported adjustment at 1-year follow up. The study employs a longitudinal, multi-method approach to examining communication processes including: standard self-report questionnaires assessing process and outcome variables collected quarterly over the course of 1 year; smartphone-based ecological momentary assessments to sample participant reports in real time; and laboratory-based couple conversations from which we derive observational measures of communicative behavior and affective expression, as well as vocal indices of emotional arousal. Participants are patients with stage II-IV breast, colon, rectal, or lung cancer and their spouses/partners, recruited from two NCI-designated comprehensive cancer centers. Results will be published in scientific journals, presented at scientific conferences, and conveyed to a larger audience through infographics and social media outlets. Findings will inform theory, measurement, and the design and implementation of efficacious interventions aimed at optimizing both patient and partner well-being. (shrink)