Scientific progress is one of the most popular topics in philosophy of science. Currently, the area offers a range of models to choose scientific progress, when addressing the specific processes that occurred in a particular discipline of science. In this article we analyze the notion of theoretical change in biochemistry, but translatable to biology and biomedical sciences by making use of the pull of theories, under one of the prospects of scientific progress, P. Kitcher, which we believe is one of (...) the best to shed clarity to the discussion of the case. (shrink)

El presente trabajo busca llevar a cabo una reconstrucción racional de un suceso histórico, tal como lo fue el surgimiento de la biología molecular, visto a la luz de la filosofía de Thomas Kuhn. Pese a que varios autores señalaron la inadecuación de la propuesta metateórica de _La Estructura_ (aún con los remiendos de la _Posdata del 69_) postulamos que es factible una reconstrucción del origen de esta (sub)disciplina bajo la categorías de paradigma-matriz disciplinar y ciencia normal con algunos refinamientos. (...) Pretendemos mostrar el surgimiento de un nuevo paradigma como la convergencia de dos líneas de investigación, una sobre la forma de la molécula de la vida, la otra sobre su función hereditaria. (shrink)

In this paper we propose to trace the historical and epistemological causes of the social construction of the image of nursing in pandemics by COVID-19, where the heroic and vocational attributes of its praxis hide the scientific and technological ones. To do so, we will begin by showing how "empirical" knowledge was historically contrasted with biomedical theoretical knowledge, medical technological praxis with the "art of caring", under a hierarchization of the professions on traditional gender roles. We will then demonstrate the (...) ways in which the romanticized image of nursing manifested itself so far during the pandemic, not only consolidating the status quo of the profession but also deepening it, by emphasizing a heroic attitude of those "on the front line of battle" as opposed to the physicians who made the decisions. Finally, we will analyze epistemologically what nursing theorists understand by "nursing praxis" in order to elucidate what is and is not visible in the constituted image of the profession. (shrink)

The goal of this article is to show that formal analysis and reconstructions may be useful to discuss and shed light on substantive meta-theoretical issues. We proceed here by exemplification, analysing and reconstructing as a case study a paradigmatic biochemical theory, the Monod-Wyman-Changeux theory of allosterism, and applying the reconstruction to the discussion of some issues raised by prominent representatives of the new mechanist philosophy. We conclude that our study shows that at least in this case mechanicism and more traditional (...) accounts are not rivals but complementary approaches. (shrink)

The structuralist reconstruction of the metabolic biochemistry here presented is a more complete and revised version than the one presented in Donolo, Federico & Lorenzano (2006). This version, as the previous one, continues with the reconstructive task initiated by César Lorenzano (2002), but advances further on those elements which remained pendent of reconstruction: applications subsequent to the paradigmatic one, for being these “too diversified and numerous” (p. 210).In line with which is said before, the objective of this new reconstruction (...) is to make the theoretical network of the biochemistry wider, in order to be able to capture the many successful applications (paradigmatic examples or exemplars) which appear in modern university textbooks. In order to accomplish this, major conceptual precisions are being introduced which will have repercussions in a modification and increased complexity of the fundamental law implicit in the text books, but still conserving the previous basic idea. Because of all this we can say that the present article goes further into the reconstruction task of the metabolic biochemistry theory. (shrink)

Los científicos suelen diferenciar entre teorías científicas explicativas y descriptivas. Para poder dar cuenta de esta diferencia es necesario contar con un análisis riguroso de las teorías científicas y la concepción estructuralista es una herramienta metateórica de análisis capaz de brindar los elementos metateóricos requeridos para abordar este tipo de estudios. El objetivo del presente trabajo es analizar una teoría que trata de dar cuenta de la actividad cooperativa de las proteínas, la teoría de Hill (tanto la originalmente publicada como (...) la presentada en los libros de texto) con el fin de elucidar el concepto de explicación utilizado en este caso. Usually, scientists differentiate between explanatory and descriptive scientific theories. To be able to analyze this difference is necessary to provide a rigorous analysis of scientific theories - the structuralist point of view is a metatheoretic tool capable of offering the metatheoretic elements needed for this. The aim of the present work is to analyze Hill's theory (both as originally published and as presented in textbooks), a theory about the cooperative activity of the proteins, in order to elucidate the concept of explanation used in it. (shrink)

If a state commits injustice, who is responsible for compensating its victims and safeguarding against future wrongdoing? Do the state’s citizens bear this responsibility? Do they all bear it equally? Avia Pasternak's and Holly Lawford-Smith's recent books address these pressing questions. Each book represents a thought-provoking attempt to derive an account of citizen responsibility for state wrongs from an account of state agency understood as group agency. Though the books demonstrate the promise of this approach to produce action-guiding advice for (...) real policymakers, they also demonstrate its limitations—in particular, its lack of attention to social structures. Here, I argue that Pasternak's and Lawford-Smith's views would be enriched by further engagement with the literature on structural injustice, which takes individuals’ perpetuation of social systems (not their implication in acts of group agency) as a central source of their remedial obligations. Through critical engagement with Pasternak and Lawford-Smith, I illustrate how a structural injustice framework could yield more attractive conclusions than a group agency framework in certain cases, better explain non-culpable forms of citizen responsibility, and allow us to theorize citizen responsibility for state action without making questionable claims about the metaphysics or social ontology of group agency. (shrink)

This chapter investigates the biography of Theodor W. Adorno and assesses his particular thoughts on musical philosophy. Adorno was born in Frankfurt am Main on September 11, 1903. While on vacation in Visp, Switzerland, he died of a heart attack on August 6, 1969. Aesthetic Theory, with Philosophy of New Music at its heart, subsumed the legacy of Adorno's entire philosophy; along with his Negative Dialectics and a planned work on moral philosophy that his early death prevented. Art and philosophy (...) played a central role from his early years onward. In Philosophy of New Music, Adorno refined the theory of musical material. The discussion of Adorno's philosophy of music gradually died down, as interest increasingly turned to engagement with the posthumous Aesthetic Theory. (shrink)

The emotional connotation of words is known to affect word and sentence processing. However, the when and how of the interaction between emotion and grammar are still up for debate. In this behavioural experiment, 35 female university students read noun phrases (NPs) composed by a determiner and a noun in their L1 (Spanish), and were asked to indicate if the NPs were grammatically correct (elmasc camareromasc) or not (*lafem tornillomasc; i.e. a gender agreement task). The type of gender (arbitrary/natural), the (...) emotionality (unpleasant/neutral), and the gender class (feminine/masculine) of the nouns were manipulated. We found an overall grammaticality effect, responses being faster in grammatically correct trials than in incorrect ones. However, the effects of emotionality and gender class varied depending on gender type. For arbitrary gender, the grammaticality effect was greater in feminine nouns than in masculine nouns and independent of emotionality. For natural gender, the grammaticality effect interacted with gender class and emotionality, this effect only emerging in unpleasant stimuli for feminine nouns. Our results reveal that it is possible to find emotional effects at the behavioural level in an intrinsically grammatical task. Yet, these effects depend on gender properties like the type of gender and the gender class. (shrink)

In this paper I argue that Fricker’s influential account of testimonial injustice (hereafter ‘TI’) should be expanded to include cases of TI from mutually neutralising countervailing prejudices. In this kind of case, the hearer is given due credibility by the speaker. I describe a relevant case, defend it from objections, highlight how it differs from extant cases of due-credibility TI and describe its distinctive features. This case demonstrates how paying attention to the way multiple prejudices operate in concert leads to (...) expanding the repertoire of cases of TI and casts light on the harms of TI. (shrink)

The concept of feasibility has received a significant amount of scrutiny in recent years. Despite the diversity of accounts, all agree on the assumption that feasibility considerations have a practical function in guiding action. However, the two most important accounts (by Gilabert and Lawford-Smith, and by Wiens) seem to scarcely speak to this practical function because they provide a third-personal reconstruction of feasibility constraints. In this paper, I argue that, to understand feasibility constraints in a way that matters for guiding (...) action, we should switch from a third-personal to an agent-centered perspective. I show that relevant constraints can be Barriers, Limitations, Boundaries, and Rubber Walls to the extent that they concern nomic impossibilities (Barriers), resources (Limitations), agents’ abilities (Boundaries) or other people’s unwillingness (Rubber Walls). Understanding constraints through the lens of their qualitatively different natures opens the way for addressing the problem of how to respond to them. (shrink)

Plato's political thought gave rise to a number of concepts and issues - such as the idea of a normative theory, the philosophical foundation of politics, the philosopher-kings, the standard of utopian theory - which have played a significant role on Western political and philosophical thought. -/- This volume aspires to bring out Plato's concept of efficacy in a normative theory. -/- By efficacy, the author means the way in which the theory conceives of its practical realization. If in the (...) Republic this issue is particularly problematic, in the Laws, instead, the claim of realizability becomes the main concern. -/- By defining the concept of efficacy and going through the main works of Plato, this conceptual and textual analysis aims to shed a new light on Plato's political thought, which is neither a utopia, nor a short term political program, but the first normative theory encompassing a theory of efficacy. (shrink)

O julgamento da ADPF 54 pelo Supremo Tribunal Federal teve como efeito a regulamentação do início da proteção constitucional à vida, silenciada na Constituição Federal de 1988 e na legislação ordinária. Todavia, a tramitação perante o Legislativo de Projeto de Lei prevendo a criminalização da interrupção da gravidez por diagnóstico de anencefalia fetal reacende as tensões acerca dos limites da atuação dos poderes Judiciário e Legislativo na concretização dos direitos fundamentais, as quais serão analisadas no presente trabalho à luz do (...) direito comparado, a fim de compreender como a regulamentação do direito à vida se estabeleceu em outros Estados Democráticos. (shrink)

What is trustworthiness? -- Being trustworthy -- Spreading trust -- Glossary -- Find out more -- Index -- About the author.

While some form of loss of control is often assumed to be a common feature of the diverse manifestations of addiction, it is far from clear how loss of control should be understood. In this paper, I put forward a concept of decrease in control in addiction that aims to fill this gap and thus provide a general framework for thinking about addictive behavior. The development of this account involves two main steps. First, I present a view of degrees of (...) control as the degree to which an agent would be responsive to potential or counterfactual sufficient reasons to do otherwise. Second, I sketch an account of the relevant control-undermining factors in addiction that is consonant with my proposed view of degrees of control. Being a high-level functional property, reasons-responsiveness is particularly well suited to frame an account of control-undermining factors that is doubly pluralistic: it encompasses the contribution of factors both internal and external to the agent, and it is consistent with various proposals as to the precise nature of the anomaly taking place in the psychology of addiction. (shrink)

This paper describes a practice innovation: the addition of formal weekly discussions of patients with prolonged PICU stay to reduce healthcare providers’ moral distress and decrease length of stay for patients with life-threatening illnesses. We evaluated the innovation using a pre/post intervention design measuring provider moral distress and comparing patient outcomes using retrospective historical controls. Physicians and nurses on staff in our pediatric intensive care unit in a quaternary care children's hospital participated in the evaluation. There were 60 patients in (...) the interventional group and 66 patients in the historical control group. We evaluated the impact of weekly meetings to establish goals of care for patients with longer than 10 days length of stay in the ICU for a year. Moral distress was measured intermittently and reported moral distress thermometer scores fluctuated. "Clinical situations" represented the most frequent contributing factor to moral distress. Post intervention, overall moral distress scores, measured on the moral distress scale revised, were lower for respondents in all categories, and on three specific items. Patient outcomes before and after PEACE intervention showed a statistically significant decrease in PRISM indexed LOS, a statistically significant increase in both code status changes DNR, and in-hospital death, with no change in patient 30 or 365 day mortality. The addition of a clinical ethicist and senior intensivist to weekly inter-professional team meetings facilitated difficult conversations regarding realistic goals of care. The study demonstrated that the PEACE intervention had a positive impact on some factors that contribute to moral distress and can shorten PICU length of stay for some patients. (shrink)

Microhabitable is a study program resulting from the collaboration between Matadero Madrid, Serpentine Galleries and INLAND--Campo Adentro. It spans a monthly seminar from September to December 2019, a publication, a radio station and a residency program articulated around reflections focused on the scale factor from the fields of art and the politics of ecology.

Il presente lavoro si propone di colmare una lacuna negli studi hegeliani analizzando in dettaglio il concetto e la teoria della sensazione di Hegel. Esso si prefigge, da un lato, di restituire il contesto sistematico entro cui Hegel discute tale concetto, fornendo un’interpretazione dei paragrafi dell’Enciclopedia ad esso dedicati; dall’altro, esso mira a fornire una ricostruzione razionale della teoria hegeliana della sensazione a partire dalla questione teorica dell’accesso epistemico del pensiero al mondo. Tale ricostruzione ruota attorno al tentativo hegeliano di (...) conciliare e rendere compatibili all’interno del proprio sistema l’istanza di un riferimento passivo a un mondo esterno e una concezione autoreferenziale del pensiero. (shrink)