This book identifies the organizing concepts of physical and biological phenomena by an analysis of the foundations of mathematics and physics.

This paper proposes an abstract mathematical frame for describing some features of biological time. The key point is that usual physical (linear) representation of time is insufficient, in our view, for the understanding key phenomena of life, such as rhythms, both physical (circadian, seasonal …) and properly biological (heart beating, respiration, metabolic …). In particular, the role of biological rhythms do not seem to have any counterpart in mathematical formalization of physical clocks, which are based on frequencies along the usual (...) (possibly thermodynamical, thus oriented) time. We then suggest a functional representation of biological time by a 2-dimensional manifold as a mathematical frame for accommodating autonomous biological rhythms. The “visual” representation of rhythms so obtained, in particular heart beatings, will provide, by a few examples, hints towards possible applications of our approach to the understanding of interspecific differences or intraspecific pathologies. The 3- dimensional embedding space, needed for purely mathematical reasons, allows to introduce a suitable extra-dimension for “representation time”, with a cognitive significance. (shrink)

Cleaning occupations, which in recent years have accounted for a not inconsiderable share of employment and job creation in France, are characterised by particularly bad working conditions and low pay. Is this situation inevitable? Are there not in fact mechanisms that might lead employers in the cleaning sector to adopt socially more responsible behaviours towards their employees? After all, the literature on corporate social responsibility suggests that the actions of consumers could be one of these mechanisms. The aim of our (...) paper is to test the impact on job quality of contact between cleaning workers and service recipients. To this end, we analyse data from a survey carried out by the French Ministry of Labour and supplemented by interviews. Our results indicate that contact with service recipients does indeed have an influence. (shrink)

The acoel worm Symsagittifera roscoffensis, an early offshoot of the Bilateria and the only well‐studied marine acoel that lives in a photosymbiotic relationship, exhibits a centralized nervous system, brain regeneration, and a wide repertoire of complex behaviors such as circatidal rhythmicity, photo/geotaxis, and social interactions. While this animal can be collected by the thousands and is studied historically, significant progress is made over the last decade to develop it as an emerging marine model. The authors here present the feasibility of (...) culturing it in the laboratory and describe the progress made on different areas, including genomic and tissue architectures, highlighting the associated challenges. In light of these developments, and on the ability to access abundant synchronized embryos, the authors put forward S. roscoffensis as a marine system to revisit questions in the areas of photosymbiosis, regeneration, chronobiology, and the study of complex behaviors from a molecular and evolutionary perspective. (shrink)

We show how a simple nonlinear dynamical system (the discrete quadratic iteration on the unit segment) can be the basis for modelling the embryogenesis process. Such an approach, even though being crude, can nevertheless prove to be useful when looking with the two main involved processes:i) on one hand the cell proliferation under successive divisions ii) on the other hand, the differentiation between cell lineages. We illustrate this new approach in the case of Caenorhabditis elegans by looking at the early (...) stages of embryogenesis, up to several hundreds of cells (lima bean larval stage). We show how the many results that have been obtained by several groups can be interpreted in terms of values for the parameters controlling the dynamical system. Furthermore, we can extend the model to the cases of genetic mutations. More precisely the teratogenetic and lethal effects are associated with abnormal variation of the control parameters with time. (shrink)

Applied Geography, A World Perspective reviews progress in applied geography in different regions of the world. It does this through the eyes of an international panel of highly regarded academic practitioners. The book offers new prospects on the use of established approaches and explores exciting new territories. Together, the contributors provide a comprehensive picture of applied geography today. This book is of relevance to faculty and graduate students in the fields of geography, planning, public policy, regional science and other related (...) social and behavioural sciences. (shrink)

This text is in Greek with extensive commentary in English and includes a general introduction, introductions to each of the two texts, appendices, glossary, and vocabulary. The Euthyphro and the Clitophon provide an ideal, exciting introduction to Plato and Greek prose.

Tome 1. Le monde, le sujet, le sens -- tome 2. Le sens, le signe, l'éros du bien et du mal.

La cognition humaine paraît étroitement liée à la structure de l'espace et du temps relativement auxquels le corps, le geste, l'intelligibilité semblent devoir se déterminer. Pourtant, ce qui, après les approches physico-mathématiques de Galilée et de Newton, fut caractérisé par Kant comme formes de l'intuition sensible, n'a cessé au cours des siècles qui suivirent de se trouver remis en cause dans leur saisie première par les développements théoriques. En mathématiques d'abord, avec les géométries non-euclidiennes, en physique ensuite, où relativité générale (...) puis théories quantiques et critiques ont dû remanier profondément l'objectivité de ces concepts pour en faire des catégories, certes toujours aussi essentielles, mais de plus en plus contre-intuitives, et maintenant en biologie où la temporalité, notamment, et la causalité se révèlent largement différentes de celles de la physique. C'est ce que nous tentons de présenter et de discuter dans ce texte en vue d'en dégager la pertinence pour la cognition elle-même. (shrink)

Naissance de la phrase -- Le recommencement du poème.

In this paper we define two types of formal biological entities corresponding to biological levels of organization, thebiolons and theorgons, the properties of which are phenomenologically analyzed and discussed.We examine then, in a rather speculative manner, how some characteristics of these entities may suggest analogies between properties of biological systems and some special features of quantum systems.

"Réfléchir sur la science, mais aussi sur les relations humaines et sur des engagements politiques et militants, tout en faisant référence à des textes anciens et à des enseignements "traditionnaires", n'est-ce pas un peu provocateur? Pourtant, la présente évocation aspire à surmonter les parcellisations et l'éclatement de la pensée - telle, en particulier, que l'Occident la conçoit trop souvent - en traitant aussi bien du raisonnable que de l'affectif, du cognitif que du ressenti et de l'intime, du communautaire que du (...) politique. Il s'agit donc de trouver les voies, les canaux, d'une correspondance des singularités personnelles, visant les relations qu'elles peuvent et doivent élaborer et entretenir, afin de signifier le dégagement d'un sens : le projet d'une humanité. Expression d'une nécessité, d'une rationalité en quelque sorte et aussi, au moins, d'une expérience. Je trouve précieux et émouvant que tradition ésotérique juive et expérience militante gauchiste puissent s'apporter, s'échanger, s'entendre pour une perspective de mise en oeuvre envisageant de devenir commune, sans pour autant mélanger abusivement ce qui doit demeurer séparé, jusqu'à ce que l'alliance conclue entre des protagonistes dûment identifiés et authentifiés soit en mesure de reprendre en termes de compatibilités et de convergence ce qui s'est présenté trop souvent dans l'histoire en termes d'irréductibilités et d'aléatoire." Extrait et adapté de Francis Bailly, Avant-Propos. (shrink)

Cette dimension d’immensité est la première qui me vient à l’esprit, dès lors qu’il est question d’aborder la nature. Nature est un mot qui avait presque disparu, de l’université en tout cas. À partir de lectures hâtives, de Foucault notamment, on en était arrivé à ne plus voir dans la nature que l’illusion voire le fantasme d’une originarité perdue. Or cela, je ne l’ai jamais pensé, je ne l’ai jamais cru, j’ai toujours pensé, au contraire, qu’avec phusis et bios, nous (...) avions un infini de la... (shrink)

The Animal Side is a manifesto on the importance of animals for human thought. It attempts to characterize the importance, for human beings, of the fact that animals exist. Adopting a philosophical and poetic approach, the book seeks to show that animals' ways of inhabiting the earth are, for human consciousness, an expansion and an exploration of what philosophers and poets have tried to name by speaking of the Open. Beginning with the story of an encounter with a deer on (...) a road at night, the book proceeds by showing that, beyond the diversity of animal life and the ways animals differ from human beings, there is a "layer of the perceptible" on which we all draw, humans and animals alike, in our own ways. At present, however, this layer itself is at risk. Thus the book can also be read as a defense and illustration of animals' modes of being, and as a plea for their survival. (shrink)

Frailty is a complex geriatric syndrome with multifactorial associated mechanisms that need to be examined more deeply to help reverse the adverse health-related outcomes. Specific inflammatory and physical health markers have been associated with the onset of frailty, but the associations between these factors and psycho-social health outcomes seem less studied. This systematic review aimed to identify, in the same study design, the potential associations between frailty and markers of inflammation, and physical or psycho-social health. A literature search was performed (...) from inception until March 2021 using Medline, Psycinfo, and EMBASE. Three raters evaluated the articles and selected 22 studies, using inclusion and exclusion criteria. Regarding biomarkers, 95% of the included studies showed significant links between inflammation [especially the higher levels of C-reactive protein and interleukin-6 ], and frailty status. Approximately 86% of the included studies showed strong links between physical health decline, and frailty status. At most, 13 studies among the 22 included ones evaluated psycho-social variables and mixed results were observed regarding the relationships with frailty. Results are discussed in terms of questioning the medical perception of global health, centering mostly on the physical dimension. Therefore, the development of future research studies involving a more exhaustive view of frailty and global health is strongly encouraged. (shrink)

Cet article examine comment, par leur discours, les femmes se construisent comme mère, dans leurs interactions avec leurs enfants adolescent-e-s, occasionnellement avec leurs maris, contribuant ainsi à la reproduction sociale des stéréotypes de masculinité et de féminité ou, au contraire, de quelle façon elles rompent avec la tradition et proposent des modèles alternatifs. Acceptent-elles ou non leur héritage symbolique en matière de genre? En voulant la reproduire, comment réinvestissent-elles la dimension genrée dans un contexte d’interactions verbales avec leurs adolescent-e-s, les (...) renvoyant ou pas à leurs « origines » culturelles? Les mères dépassent-elles le modèle de binarité des sexes traditionnel pour parvenir à un modèle agentif? À travers le continuum de normativité et d’agentivité, l’entre-deux prend tout son sens : en quoi l’imaginaire linguistique constitue-t-il un espace à construire, un « à travers »? This research paper examines the way women discursively construct themselves as mothers, in their interactions with their teenage children, and occasionally with their husbands, and the way they thus contribute to the social reproduction of manhood and womanhood stereotypes or on the contrary break with the tradition to propose alternative models. Do they or don’t they accept their symbolic heritage as regards sex and gender? While intending to reproduce this heritage, how do they reinvest the gendered dimension in the context of verbal interaction with their teen-agers, sending them back or not to their cultural “origins”? Do the mothers go beyond the traditional binary model of sex and gender to reach an agentive model? Through the continuum that goes from normativity to agentivity, the idea of an in-between stage makes sense: in what way does the linguistic imaginary constitute an area to be forged, a crossing space? (shrink)