After decades of absence, the federal legalization of hemp in the U.S. positions the crop as an innovative, plant-based input for conventional products. Through an application of the diffusion of innovations theory, this study responds to identified research needs made by hemp stakeholders and the existing literature by modeling the influence of innovation characteristics on propensity to use hemp products among Vermont consumers. Findings reveal that attributes associated with relative advantage and trialability significantly influence propensity to use at least one (...) type of hemp product, as well as use multiple types of hemp products. This highlights particularly salient points for hemp stakeholders engaged in the marketing and communication of hemp products. Findings contribute to informed strategy creation for producers, institutions, and other stakeholders operating in this nascent industry, where data and research continue to be limited. (shrink)

In response to Germain argument that evolution by natural selection has a limited explanatory power in cancer, Lean and Plutynski have recently argued that many adaptations in cancer only make sense at the tumor level, and that cancer progression mirrors the major evolutionary transitions. While we agree that selection could potentially act at various levels of organization in cancers, we argue that tumor-level selection is unlikely to actually play a relevant role in our understanding of the somatic evolution of (...) human cancers. (shrink)

This paper studies the capture of organisms and materials in soil construction – a branch of ecological engineering dedicated to making soil in order to compensate for soil degradation. This approach takes all organisms to be ‘ecosystem engineers’, and often refers to earthworms as ‘collaborators’ in making soil. I examine the claim that such a convocation of worms amounts to a redistribution of agency and the underlying assumption that form-taking is the shaping of raw matter according to pre-existing forms. Drawing (...) on processual anthropology, I question the distinction between living and material components of soils, and between growing and making. I elaborate on soil scientists’ description of soil growth as pedogenesis in order to propose a view in which soil materials, along with organisms, participate in soil’s transformative and generative fluxes. I envisage the process as a concrescence, an experimentation that brings humans, worms, and soil materials together in new ways. (shrink)

Previous research suggests that social anxiety symptoms are maintained and intensified by inflexible emotion regulation (ER). Therefore, we examined whether trait-level social anxiety moderates ER flexibility operationalised at both between-person (covariation between variability in emotional intensity and variability in strategy use across occasions) and within-person (associations between emotional intensity and strategy use on a given day) levels. In a sample of healthy college-aged adults (N = 185, Mage = 21.89), we examined overall and emotion-specific intensities (shame, guilt, anxiety, anger, sadness) (...) and regulatory strategies (i.e. experiential avoidance, expressive suppression, and rumination) in response to each day’s most emotionally intense event over 6 days. During the study period, we found a positive association between variability in emotional intensity and variability of experiential avoidance in individuals with lower, rather than higher, levels of trait social anxiety after controlling for key covariates (i.e. gender, personality traits, and stress exposure). However, we did not find evidence for the moderating role of trait social anxiety in ER flexibility assessed at within-person levels. Our findings highlight the need to delineate dynamic ER flexibility across everyday events. (shrink)

This paper is part of a larger project defending of the foundations of microeconomics against recent criticisms by philosophers. Here, we undermine one source of these criticisms, arising from philosophers' disappointment with the performance of microeconomic tools, in particular game theory, when these are applied to normative decision theory. Hollis and Sugden have recently articulated such disappointment in a sophisticated way, and have argued on the basis of it that the economic conception of rationality is inadequate. We argue, however, that (...) their claim rests upon a misunderstanding of the concept of a game as it is used in microeconomics. (shrink)

Toute guerre se remporte avec des hommes et des munitions, y compris celle des idées. Aujourd'hui l'histoire, la politique, l'économie, la culture, le droit sont des champs de bataille. À nous d'y triompher de la pensée unique. Beaucoup ont déjà pris la plume, tels Jean Sévillia, Philippe de Villiers ou Mathieu Bock-Côté. Mais à cette aventure intellectuelle, le droit reste étranger. Chose curieuse, au regard de son immixtion dans nos vies, réglées comme des horloges suisses par ses rouages. Mal interprété, (...) il regorge d'idées fausses, parfois sciemment entretenues par nos législateurs à des fins politiques. Remettre le droit à l'endroit? C'est l'objet insolite de cet ouvrage. Les hommes naissent-ils réellement libres et égaux en droit? Nos élus nous coûtent-ils trop cher? La naissance d'un étranger en France le rend-elle nécessairement français? Le droit européen est-il vraiment supérieur au droit national? Trente questions pour y voir clair et combattre les idées reçues. (shrink)

Imagine asking a typical, well informed, contemporary philosopher whether or not she considered biology to be a science. Our informant, being a philosopher, would not necessarily respond with the straightforward “of course” that would be expected from anyone else. She might first reason through a complicated and heavily qualified definition of science, or she might distinguish certain parts of biology that she held to be more clearly scientific than others. If she were partial to a certain sort of critical stance, (...) she might question the political basis for wishing to dignify certain parts of our inquisitive practice with the honorific ‘scientific’ in the first place. But there is at least one thing that she would almost certainly not do. She would not simultaneously embrace a version of the conventional philosophical view of science and deny that biology is a science. This is despite the fact that, as she will acknowledge, biology exploits a range of methodologies and explanatory strategies that have not yet admitted of systematic, consensual philosophical explication. (shrink)

In its last round of publications in September 2012, the Encyclopedia Of DNA Elements (ENCODE) assigned a biochemical function to most of the human genome, which was taken up by the media as meaning the end of ‘Junk DNA’. This provoked a heated reaction from evolutionary biologists, who among other things claimed that ENCODE adopted a wrong and much too inclusive notion of function, making its dismissal of junk DNA merely rhetorical. We argue that this criticism rests on misunderstandings concerning (...) the nature of the ENCODE project, the relevant notion of function and the claim that most of our genome is junk. We argue that evolutionary accounts of function presuppose functions as ‘causal roles’, and that selection is but a useful proxy for relevant functions, which might well be unsuitable to biomedical research. Taking a closer look at the discovery process in which ENCODE participates, we argue that ENCODE’s strategy of biochemical signatures successfully identified activities of DNA elements with an eye towards causal roles of interest to biomedical research. We argue that ENCODE’s controversial claim of functionality should be interpreted as saying that 80 % of the genome is engaging in relevant biochemical activities and is very likely to have a causal role in phenomena deemed relevant to biomedical research. Finally, we discuss ambiguities in the meaning of junk DNA and in one of the main arguments raised for its prevalence, and we evaluate the impact of ENCODE’s results on the claim that most of our genome is junk. (shrink)

The aim of this paper is to assess the relevance of somatic evolution by natural selection to our understanding of cancer development. I do so in two steps. In the first part of the paper, I ask to what extent cancer cells meet the formal requirements for evolution by natural selection, relying on Godfrey-Smith’s (2009) framework of Darwinian populations. I argue that although they meet the minimal requirements for natural selection, cancer cells are not paradigmatic Darwinian populations. In the second (...) part of the paper, I examine the most important examples of adaptation in cancer cells. I argue that they are not significant accumulations of evolutionary changes, and that as a consequence natural selection plays a lesser role in their explanation. Their explanation, I argue, is best sought in the previously existing wiring of the healthy cells. (shrink)

This book traces the roots of the contemporary abortion debate in the tradition of existential philosophy of the Sartrian type by investigating the work of four feminist writers on abortion—each with a specific focus: Simone de Beauvoir, Mary Daly, Carol Gilligan, and Beverly Wildung Harrison. _No Higher Court_ attempts to envisage a pro-life feminism that is able to provide a "new world for women without abortion as its linchpin and bedrock.".

The notion of biological function is fraught with difficulties—intrinsically and irremediably so, we argue. The physiological practice of functional ascription originates from a time when organisms were thought to be designed and remained largely unchanged since. In a secularized worldview, this creates a paradox which accounts of functions as selected effect attempt to resolve. This attempt, we argue, misses its target in physiology and it brings problems of its own. Instead, we propose that a better solution to the conundrum of (...) biological functions is to abandon the notion altogether, a prospect not only less daunting than it appears, but arguably the natural continuation of the naturalisation of biology. (shrink)

Public conversation about biological contributors to mental disorder often centers on whether the problem is “biological or not.” In this paper, we propose moving beyond this bifurcation to a very different question:how exactlyare these problems understood to be biological? Specifically, we consider four issues around which different interpretations of the body’s relationship to mental disorder exist:1. The body’s relationship to day-to-day action; 2. The extent to which the body is changeable; 3. The body’s relationship to context; 4. The degree to (...) which states of the body directly cause mental disorder.Drawing on the work of Merleau-Ponty and other phenomenologists, we examine different responses to these questions and associated implications for how mental health treatment and recovery come to be experienced. Finally, we consider broader questions these patterns raise, including why certain portrayals of the brain dominate public attention and how to foster more deliberation in this regard. (shrink)

Audio features such as inharmonicity, noisiness, and spectral roll-off have been identified as correlates of “noisy” sounds. However, such features are likely involved in the experience of multiple semantic timbre categories of varied meaning and valence. This paper examines the relationships of stimulus properties and audio features with the semantic timbre categories raspy/grainy/rough, harsh/noisy, and airy/breathy. Participants rated a random subset of 52 stimuli from a set of 156 approximately 2-s orchestral instrument sounds representing varied instrument families, registers, and both (...) traditional and extended playing techniques. Stimuli were rated on the three semantic categories of interest, as well as on perceived playing exertion and emotional valence. Correlational analyses demonstrated a strong negative relationship between positive valence and perceived physical exertion. Exploratory linear mixed models revealed significant effects of extended technique and pitch register on valence, the perception of physical exertion, raspy/grainy/rough, and harsh/noisy. Instrument family was significantly related to ratings of airy/breathy. With an updated version of the Timbre Toolbox, we used 44 summary audio features, extracted from the stimuli using spectral and harmonic representations, as input for various models built to predict mean semantic ratings for each sound on the three semantic categories, on perceived exertion, and on valence. Random Forest models predicting semantic ratings from audio features outperformed Partial Least-Squares Regression models, consistent with previous results suggesting that non-linear methods are advantageous in timbre semantic predictions using audio features. Relative Variable Importance measures from the models among the three semantic categories demonstrate that although these related semantic categories are associated in part with overlapping features, they can be differentiated through individual patterns of audio feature relationships. (shrink)

Quizá no sea desacertado destacar que cuando Étienne Balibar afirma que el sujeto-ciudadano rousseauniano constituye una «figura propiamente revolucionaria», no está simplemente mencionándolo desde una perspectiva teórico-política, pues está haciendo ver que la dualidad que comporta supone una figura revolucionaria en un sentido lingüístico y especulativo. En este artículo, nuestro propósito no es otro que analizar el triple alcance de la «invención teórica de Rousseau». Que las significaciones conceptuales no puedan ser simples o unívocas, es lo que en buena medida (...) intentaremos poner de relieve siguiendo su interpretación de algunas de las nociones medulares del Contrato social de Rousseau. (shrink)

The ways in which other animal species can be informative about human biology are not exhausted by the traditional picture of the animal model. In this paper, I propose to distinguish two roles which laboratory organisms can have in biomedical research. In the more traditional case, organisms act as surrogates for human beings, and as such are expected to be more manageable replicas of humans. However, animal models can inform us about human biology in a much less straightforward way, by (...) being used as measuring devices—what I call their instrumental role. I first characterize this role and provide criteria for it, before illustrating it with some examples from biomedical research, especially cancer research. In such an instrumental role, phenotypes are not expected to phenocopy human phenomena, but instead have the purely instrumental value of detecting or measuring differences. I argue that the instrumental role is more prevalent than might first be suspected, and that some characteristics of contemporary biomedical research are increasingly shifting the use of laboratory organisms to the instrumental role. Finally, in light of the distinction proposed, I discuss the meaning of the expression “animal model”. (shrink)

William James’s theory of emotion has been controversial since its inception, and a basic analysis of Cannon’s critique is provided. Research on the impact of facial expressions, expressive behaviors, and visceral responses on emotional feelings are each reviewed. A good deal of evidence supports James’s theory that these types of bodily feedback, along with perceptions of situational cues, are each important parts of emotional feelings. Extensions to James’s theory are also reviewed, including evidence of individual differences in the effect of (...) bodily responses on emotional experience. (shrink)

Sinous voulions tirer une ligne d'unité à travers les branches si disparates qui se sont épanouies sur les racines cartésiennes, nous pourrions affirmer que l'homme est rentré en lui-même et de plus en plus profondément jusqu'à nos jours. Son regard s'est détourné d'un objet extérieur pour considàrer le produit intérieur de son acte d'esprit, puis pour essayer de pénétrer dans le mystère même de cet acte. L'homme s'est vu responsable de l'homme. Son existence lui est donnée mais il ne peut (...) la maintenir sans lui fournir une forme, une essence dont la spécification dépendra de son “je” libre. Tout un éventail d'humanismes s'est alors déployé à partir d'une concrétude enfouie irrévocablement et désespérément dans la condition charnelle jusqu'à la concrétude la plus spirituelle de la pensée réflexive contemporaine. En un mot, l'histoire de la philosophic moderne devient l'histoire de la prise de conscience de l'immanence. (shrink)

The objective of this study is to analyze the writing of three neo-scholastic writers of the twentieth century -- Marcel Chossat, Pedro Descoqs, and Francis Cunningham -- who happen to dispute the prevailing view of Thomists that St. Thomas Aquinas does indeed hold a doctrine of thereal distinction of essence and existence in created being. The approach utilized will be basically historical: we start with the year 1910, the year in which Marcel Chossat rekindled the ever-smoldering embers of the essence-existence (...) controversy with his claim that Aquinas never held such a doctrine. In order to justify another treatment of what has been called “the endlessly rehashed question”, we try to show that the arguments put forth by the three thinkers in question an are based on considerable and weighty linguistic grounds which others in the debate have tended to dismiss. We conclude by saying that any discussion of the real distinction controversy must take a “linguistic turn” if it is to have any hope of being fruitful. (shrink)

Our commentary aims to show that the COVID-19 pandemic has amplified existing barriers to healthcare in England for ethnic minority and migrant women. We expose how the pandemic has affected the allocation of healthcare resources leading to the prioritisation of COVID-19 patients and suspending the equal access to healthcare services approach. We argue that we must look beyond this disruption in provision by examining existing barriers to access that have been amplified by the pandemic in order to understand the poorer (...) health outcomes for women in ethnic minority and migrant communities. The reflection focuses on racialised medical perceptions, gendered cultural norms including information barriers and stigma, and specific legal barriers. (shrink)

This article analyzes the influence of Chinese Neo-Confucianism on the development of German idealism. Information obtained by Leibniz from Jesuit missionaries included key concepts in Neo-Confucian philosophy that not only confirmed Leibniz’s belief in the universality of his organic image of the cosmos but also influenced Leibniz’s later writings. Such influence is also exhibited in Kant’s work, especially in his crucial noumenon-phenomenon distinction, as well as in Hegel’s phenomenology and philosophy of history. Recognition of these influences, unacknowledged by either Kant (...) or Hegel, enhances our assessment of the import of both Neo-Confucianism and German idealism in international religio-philosophical discourse. (shrink)