We inquire into the notions of ‘boundary’ and ‘cluster’ in the fields of medical genetics, pharmacogenetics, and population genetics. First we show that the two notions are not well discussed in literature. Then we propose a promising explication of them, in which we argue that clustering is always ‘property laden’, that is, fundamentally dependent on decisions about the properties to be taken into account. In particular we suggest three different kinds of properties that have a role in these decisions. That (...) is, we conclude that boundaries and clusters among humans depend on our way of considering nature. Concepts of ‘race’ and ‘ethnic group’ are discussed too, since they are the most used clusters among humans. (shrink)

This memoir consists of two parts, of which the first deals with the foundations of the theory of the struggle for existence, and begins with the introduction of the important concept of quantity of life, besides that of population. The fundamental equations are then established for the case where the individuals of a biological association mutually devour each other, the reasoning being based on the principle of encounters and on the fundamental hypothesis of the existence of equivalents of the individuals (...) constituting the different species which form the association.Having now obtained the equations which determine the rates of change of the numbers of individuals and of the quantities of life of the species, the memoir proceeds to find the equations relating to the stationary state, by establishing theorems which are afterwards applied for the purpose of obtaining the three general laws of the fluctuations. This investigation of the equilibrium state is then followed by the determination of the integrals of the fluctuation equations, and the deduction from these of their most important consequences.The second part of the memoir contains the enumeration and demonstration of the general laws of the struggle for existence, which flow from the discussion of the principles and the integrals obtained in the first part. In this way there is established a new sort of dynamics, demographic dynamics, which, though substantially different from the dynamics of material systems, is developed from an analogous point of view.The second part begins with the principle of the conservation of demographic energy, according to which there are two sorts of energy, one actual and one potential, which transform mutually the one into the other. This principle is the analogue of the principle of conservation of mechanical energy. It is followed by the enunciation of the three laws relating to the biological fluctuations, the experimental verification of which has been investigated by several naturalists. The success which has attended their efforts is well known.Everybody knows the importance ofHamilton's principle in mechanics and in all the domains of physical science. An analogous variation principle can be found in biology, and from it one can deduce the fluctuation equations in the canonical Hamiltonian form and also in the form of a Jacobian partial differential equation. Their integrals in involution from the subject next studied, and in this way are found cases where the integration is reducible to quadratures.Hamilton's principle leads to the principle of least action . There exists also in biology a closely related principle, which may be called the principle of least vital action. Its analytical form is such that it requires the existence of a true minimum, a state of affairs which does not always hold good in the analogous case in mechanics.Die Abhandlung besteht aus zwei Teilen: Der erste ist den Grundlagen der Theorie des Kampfes ums Dasein gewidmet. Man beginnt damit, neben der Bevölkerung die Menge des Lebens einzuführen, welche eine sehr wichtige Rolle spielt. Man geht dann dazu über, die Grundgleichungen für den Fall aufzustellen, in welchem die Individuen einer biologischen Assoziation sich gegenseitig auffressen. Man wendet das Prinzip der Begegnungen an und stützt sich auf die Grundhypothese der Existenz von Individuenäquivalenten der verschiedenen Arten, welche die Assoziation bilden.Wenn man die Gleichungen, welche die Variationen der Individuenzahlen und der Lebensmengen der Arten liefern, gefunden hat, so schreitet man zu den statischen oder Gleichgewichtsgleichungen fort und findet so die Theoreme, die man alsdann benutzt, um die drei allgemeinen Gesetze der Fluktuationen zu erhalten.Nach dem Studium des Gleichgewichtes geht man dazu über, die verschiedenen Integrale der Fluktuationengleichungen zu finden und zieht endlich aus ihnen die wichtigsten Folgerungen.Im zweiten Teile werden die allgemeinen Gesetze des Kampfes ums Dasein, welche aus der Diskussion der Prinzipien und der im ersten Teil gewonnenen Integrale stammen, ausgesprochen und bewiesen. Man baut so eine neue Dynamik auf: die demographische Dynamik, welche, obschon sie wesentlich verschieden von derjenigen der materiellen Systeme ist, sich nach einem analogen Gesichtspunkt entwickelt.Man beginnt in diesem zweiten Teil mit dem Prinzip der Erhaltung der demographischen Energie, nach welchem zwei Energien, die aktuelle und die potentielle, sich ineinander verwandeln. Wir haben hier eine Analogie zum Prinzip der Erhaltung der mechanischen Energie. Dann werden die drei Gesetze der biologischen Fluktuationen formuliert. Für sie haben verschiedene Naturforscher experimentelle Bestätigungen gesucht. Man kennt den Erfolg ihrer Bemühungen.Alle Welt kennt die Bedeutung des Prinzips vonHamilton in der Mechanik und in allen Gebieten der Physik. Man kann ein dem Variationskalkül analoges Prinzip in der Biologie finden. Aus ihm kann man die Fluktuationsgleichungen in der kanonischen Form vonHamilton und in der Gestalt einer Gleichung mit partiellen Differentialquotienten vonJacobi herleiten. Ihre Integrale bilden den Gegenstand der folgenden Studien. Man findet Fälle, in denen die Integration sich auf Quadraturen reduziert.Das Prinzip vonHamilton zieht das Prinzip der kleinsten Wirkung oder das Prinzip vonMaupertuis nach sich. Auch in der Biologie gibt es ein mit dem vorgenannten zusammenhängendes Prinzip, welches man das Prinzip der kleinsten vitalen Wirkung nennen kann. Seine analytische Form ist derart, dass es sich um ein wahres Minimum handelt, das im analogen Fall in der Mechanik nicht immer zutrifft. (shrink)

The aim of this article is to show that the trinitarian theology of Origen of Alexandria shares the same theoretical structure as the henology of Plotinus. In particular, there is a strong correspondence between the trinitarian hypostases in Origen and the moments of the One in Plotinus: the Father is the One; the Son-Logos is the Intelligence; finally, the Holy Spirit is the Soul. Both Origen and Plotinus seem to assume the ontological difference between God, who, on the one hand, (...) comes before the generation of the Son, i.e., before the distinction between Father and Son, and who is indeed God, and, on the other hand, God who is the Father as he generates the Son and who, by doing so, distinguishes himself from himself. The system of ideas which represents the basis of both the theology of Origen and the henology of Plotinus is evidently a Platonic one. (shrink)

We investigated the contributions of familiarity of setting, self-relevance and self-projection in time to episodic future thinking. The role of familiarity of setting was assessed, in Experiment 1, by comparing episodic future thoughts to autobiographical future events supposed to occur in unfamiliar settings. The role of self-relevance was assessed, in Experiment 2, by comparing episodic future thoughts to future events involving familiar others. The role of self-projection in time was assessed, in both Experiments, by comparing episodic future thoughts to autobiographical (...) events that were not temporal in nature. Results indicated that episodic future thoughts were more clearly represented than autobiographical future events occurring in unfamiliar setting and future events involving familiar others. Our results also revealed that episodic future thoughts were indistinguishable from autobiographical atemporal events with respect to both subjective and objective detail ratings. These results suggest that future and atemporal events are mentally represented in a similar way. (shrink)

Vito Tanzi offers a truly comprehensive treatment of the economic role of the state in the twentieth and twenty-first centuries from a historical and world perspective. The book addresses the fundamental question of what governments should do, or have attempted to do, in economic activities in past and recent periods. It also speculates on what they are likely or may be forced to do in future years. The investigation assembles a large set of statistical information that should prove useful (...) to policy-makers and scholars in the perennial discussion of government's optimal economic roles. It will become an essential reference work on the analytical borders between the market and the state, and on what a reasonable 'exit strategy' from the current fiscal crises should be. (shrink)

The development of the various themes of Catholic Social Teaching is based on numerous papal documents and ecclesiastical statements. While this paper provides a summary of a number of these documents, this paper focuses on two themes: the common good and care of the environment, and on three documents authored by Pope John Paul II in 1990, by Pope Benedict XVI in 2010, and by Pope Francis in 2015. By analyzing these documents from an engineer’s perspective, the author proposes a (...) model for Socially Responsible Engineering. The proposed model is intended to serve as a guide for engineering students and practicing engineers of all faith traditions and to those with no faith tradition at all who wish to incorporate CST in the daily conduct of their personal and professional lives; to provide guidance for the professional the author terms the aspiring Socially Responsible Engineer; and to offer engineers a preferred alternative to the undesirable aspects of the technocratic paradigm. While intended primarily for engineers, this document also serves as a guide for those with expertise in social justice and who, by gaining a better understanding of the thought processes of engineers, can become better mentors for engineering students and practicing engineers seeking to incorporate CST into their daily lives. (shrink)

The aim of the article is to reflect on the communication model of fake news, starting from the assumption that fake news items are not mere falsehoods (e.g., trivial lies) nor something completely new.Drawing inspiration from the work of Umberto Eco, I will investigate the idea that today’s viral fake news can be aligned with the hermetic paradigm he outlined. Then I will consider another communicative model: that of gossip. Thanks to these two models, I will support the thesis that (...) fake news are not something to eliminate or to correct according to the criterion of evidence or truth, but rather something to live with, corresponding to a potentiality of discourse, that is to detect and to analyze. (shrink)

This volume provides a unique overview of methodologies that are conducive to a successful legal transplant in East Asia and Oceania. Each chapter is drafted by a scholar who holds direct professional experience on the legal transplant considered and has a distinctive insight into the pragmatic difficulties related to grafting an alien institution into a legal tradition. The range of transplants includes the implementation of contractual obligations, the regulation of commercial investments and the protection of the environment. The majority of (...) recent legal reforms in these geographical areas have aimed at improving national economic performance and fostering trade and have been directly inspired by European and North American institutional experiences. There is also, however, a tendency to couple economic reforms, aimed at attracting foreign investment, with constitutional reforms that improve the protection of individual rights, the environment and the rule of law. (shrink)

Investigating the reality and significance of racial categories, Remapping Race in a Global Context examines the role of race in human genomics, biomedicine, and struggles for social justice around the world. In this book, biologists, anthropologists, historians, and philosophers inspect critical questions around the biological reality of race and how it has been understood in different national and regional contexts. The essays also examine debates on the usefulness of race in medical and epidemiological studies. With focus on the fields of (...) human genomics and biomedicine, this book presents critical findings on whether and how race might be ethically and epistemologically justified in our age of personalized medicine, mass surveillance, and biased algorithms. The book will be of interest to researchers and advanced students in a broad range of scientific and humanistic disciplines, including biology, anthropology, geography, philosophy, cultural or community studies, critical race theory, and any field concerned with the deep racial dividing lines running across societies globally. (shrink)

This article presents for the first time in english lesniewski's analysis of russell's antinomy as the analysis is given in lesniewski's 1914 paper "czy klasa klas, nie podporzadkowanych sobie, jest podporzadkowana sobie?" is the class of classes which are not subordinate to themselves subordinate to itself? it is shown how the concepts appearing in this paper, written in colloquial polish, were later incorporated and expressed as fundamental axioms and theorems of his theory of collective classes, mereology. in the 1914 paper (...) he asserted: i call any object p an object subordinate to a class k if in some sense of the expression "a" the following two conditions hold: 1) k is a class (of objects) "a", 2) p is an "a". using this explication of "p is subordinate to a class k," he showed that both of the following statements are false: a) the class of classes which are not subordinate to themselves is subordinate to itself, b) the class of classes which are not subordinate to themselves is not subordinate to itself; thus showing that russell's antinomy cannot be generated since its initial assumptions are false. (shrink)

This volume presents a collection of essays on objectivity in legal discourse. Has law a distinctive type of objectivity? Is there one specific type of legal objectivity or many, depending on the observatory language utilized? Is objectivity fit for law? The analyses in the various contributions show that the Cartesian paradigm of objectivity is not relevant to the current legal discourse, and new forms of legal objectivity are revealed instead. Each essay, in its distinctive way, analyses the strong commitment of (...) law to objectivity, shedding light on the controversies that surround it. (shrink)

The concept of judicial objectivity is a cornerstone of modern legal systems. This article discusses the interplay between the lexical uses of the concept of judicial objectivity in cases that review the judicial impartiality of the court. The data for this project is retrieved from a large sample of cases from Hungary, Italy, Lithuania, Slovakia, Slovenia, Spain and the UK. The analysis of the data shows that in the case of alleged judicial bias, the concept of objectivity is referred to (...) in order to justify a series of judicial activities. In particular, the study provides a strong indication of what Legrand called ‘pre-judices’, which are the cultural aspects that are embedded in the process of the professional socialisation of each legal system. (shrink)

The post-truth regime is a regime in which certain central categories of modernity seem to be inadequate: that of truth as correspondence, that of truth as verification, and that of truth as sincerity. This reflection aims at proposing a shift from the category of truth to the category of legitimacy, in order to rethink those of correctness, objectivity, adequacy. The advantage potentially offered by the concept of legitimacy, with regards to that of truth, has to do with the reference to (...) a given context, with an element of social recognition and a processual dimension, which makes the management of discourses more flexible, without abdicating to their deregulation. (shrink)

L’articolo mette in luce due paradossi, il primo dei quali è dato dal fatto che proprio in quelle terre dove si affermò la radicale impostazione anti-umanistica del protestantesimo ebbe a scaturire una straordinaria fioritura dell’umano fino alla consacrazione della libertà come principio della ricerca scientifica e del vivere civile. Il secondo paradosso è dato dalla manifestazione in quelle stesse terre meno di un secolo fa dell’ideologia nazista. La tesi sostenuta è che il principio protestante di fatto affermatosi nella coscienza europea (...) consiste non tanto nella teoria teologica della giustificazione (sola Gratia, sola Fide, sola Scriptura) quanto nella affermazione filosofica e politica della libera coscienza personale, il cui evento decisivo fu la dichiarazione di Lutero alla Dieta di Worms. Ma proprio il carattere abissale della libertà e il destino di interpretazione infinita cui la consegnò Lutero sono anche all’origine di quel disagio della coscienza e dell’esistenza da cui sorse il malessere che portò al totalitarismo.Nel sostenere la tesi enunciata l’articolo si struttura secondo quattro movimenti: 1) argomentazione sul carattere radicalmente anti-umanistico del protestantesimo; 2) argomentazione sui notevoli effetti umanistici storicamente prodotti dalla Riforma protestante; 3) argomentazione sulle possibili connessioni tra il terreno preparato dalla Riforma nella società tedesca e il sorgere in essa dell’ideologia nazionalsocialista; 4) considerazioni finali sulla dialettica della libertà umana. (shrink)

"Teaching after all is about knowing children well" -- from A Letter to Teachers "Perrone has given us a gift, a book worth reading over many times, an important reflection on his many years of close observation of schools and school people, parents, teachers, children, and their communities." -- Deborah W. Meier, principal, Central Park East Secondary School Simple, elegant and full of common sense, these reflections on the art of teaching address the deepest concerns teachers have for their work (...) with children and young people. (shrink)

A movement asking to take race out of medicine is growing in the US. While we agree with the necessity to get rid of flawed assumptions about biological race that pervade automatic race correction in medical algorithms, we urge caution about insisting on a blanket eliminativism about race in medicine. If we look at racism as a fundamental cause, in the sense that this notion has been introduced in epidemiological studies by Bruce Link and Jo Phelan, we must conclude that (...) race is indispensable to consider, investigate, and denounce the health effects of multilevel racism, and cannot be eliminated by addressing more specific risk factors in socially responsible epidemiology and clinical medicine. This does not mean that realism about human races is vindicated. While maintaining that there are no human races, we show how it is that a non-referring concept can nonetheless turn out indispensable for explaining real phenomena. (shrink)

Hence, the title The Heritage of Kazimierz Ajdukiewicz seems to reflect the general idea of this collection. Most papers collected here were specially ...

In this article, we tackle the epistemological and ethical issues related to the use of race concepts in the genomics of sport performance and sport-related concussion (SRC). In the first part of the article, we show how the concept of race is ubiquitous in scientific literature, besides the fact that ‘race’ as other analogous population descriptors like ‘ancestry’ and ‘continent’ carry ancestral genetic heterogeneity and therefore they cannot be used to infer any kind of genetic or physiological property. Then, we (...) investigate the question of whether genomics research focusing on racial categories and race-specific genes of sport performance and of risk of health outcomes due to repetitive head impacts (RHI) is justified from an epistemological point of view, arguing that it is not; we show that the evidence supporting the existence of genetic variants determining an elite athlete status or a predisposition to health outcomes after SRC is scarce, and the use of racial categories (e.g. African or Black, Caucasian or White, Asian, etc.) as proxies for genetic variants associated with an elite athlete status/a predisposition to health outcomes after SRC is ill-conceived. In the second part of the article, we analyze the main ethical issues concerning the reification of race concepts in sport genomics, also considering the more general issue of the ethical and social impact of the use of a genetic framework in the explanation of individual differences in sport performance and SRC. (shrink)

Lack of understanding about the relationship between federal and state educational institutions brings confusion into discussions of democracy, equity and equality in schools. The 'right to education' continues to be espoused by American society as a birthright, yet it does not figure in federal documentation. This matter has repeatedly come to the attention of legislative courts, who have insisted that the question of education as a fundamental right be addressed. Numerous court cases have attempted to bring closure on this issue, (...) on the basis of such abstractions as national rights, equal access, opportunity and economic disparity among the petitions. However, legal judgments remain inconclusive, reiterating that education remains a state legislative issue. This paper explores the implications of a fundamental right to education through an examination of federal and state legal litigation, discussing the philosophical and ideological roots of discussion of rights and democratic values, and evaluating how federal and judicial participation contributes to overall misunderstanding regarding public schooling. (shrink)

En dépit de sa date de parution un peu ancienne, il semble important de signaler cet ouvrage aux lecteurs de ce numéro de Clio. Les évaluations péjoratives de la conversation féminine sont, comme on sait, un des lieux communs les plus anciens et les plus ancrés ; « bavardage », « caquetage », « ragots »... sont quelques-uns des termes métaphoriques qui stigmatisent une façon d'échanger et un style de contenu situés au plus loin de la parole sûre et pondérée (...) des hommes. Jennifer Coates... (shrink)

In medicine, racial differences are frequently presented as part of the best explanation of differences in the risk of diseases. The problem of using racial classification in biomedical research has become important because of its ethical consequences in society. However, the biological relevance of the concept of race cannot be established by any ethical argument and the epistemological role of racial categorisation requires clarification. In this paper, different issues related to the concept of race are considered. This paper analyses the (...) semantic problem concerning the definition of race, considers the ontological problem of race, drawing attention to the biological evidence for genetic differences among human groups, and presents a promising epistemological approach to the problem of race. The purpose of the paper is to examine whether, or when, racial categories belong in biological explanations. It shows that the concept of race cannot be justified in biology because it does not lead to successful predictions, and that genetic discontinuities are sufficient to explain differences in diseases but not needed in the explanation. The biomedical field should search for genetic patterns related to diseases, and should not assume racial discontinuities among human groups and use racial clusters as proxies for undetected genetic patterns. (shrink)

Measuring perceived similarity is an important issue in visual perception of faces, since a measure of the perceived similarity between faces may be used to investigate fundamental tasks like face categorization and recognition. Despite its fundamental role, measuring perceived similarity between faces is not trivial from both a theoretical and methodological point of view. In this paper we present theoretical arguments that undermine the method currently most used to measure perceived similarity between faces in visual perception, and we propose an (...) alternative method. We finally compare the two methods and find some empirical evidence that the proposed method can provide a more reliable evaluation of the perceived similarity between faces. (shrink)