The translocation of proteins across membranes is a central problem in biology. Regardless of the system in question, delivering proteins across a given membrane relies on many of the same basic themes. At the same time, however, each membrane translocation system, beit signal‐gated or signal‐assembled, makes use of components unique to that system. The latest findings on protein translocation across a variety of biological membranes have been presented in a recent review article.1 BioEssays 25:1154–1157, 2003. © 2003 Wiley Periodicals, Inc.

In concert with the selective pressures affecting protein folding and function in the extreme environments in which they can exist, proteins in Archaea have evolved to present permanent molecular adaptations at the amino acid sequence level. Such adaptations may not, however, suffice when Archaea encounter transient changes in their surroundings. Post‐translational modifications offer a rapid and reversible layer of adaptation for proteins to cope with such situations. Here, it is proposed that Archaea further augment their ability to survive changing growth (...) conditions by modifying the extent, position, and, where relevant, the composition of different post‐translational modifications, as a function of the environment. Support for this hypothesis comes from recent reports describing how patterns of protein glycosylation, methylation, and other post‐translational modifications of archaeal proteins are altered in response to environmental change. Indeed, adjusting post‐translational modifications as a means to cope with environmental variability may also hold true beyond the Archaea. (shrink)

Bayes’ formula is a fundamental statistical method for inference judgments in uncertain situations used by both laymen and professionals. However, since people often fail in situations where Bayes’ formula can be applied, how to improve their performance in Bayesian situations is a crucial question. We based our research on a widely accepted beneficial strategy in Bayesian situations, representing the statistical information in the form of natural frequencies. In addition to this numerical format, we used five visualizations: a 2×2-table, a unit (...) square, an icon array, a tree diagram, and a double-tree diagram. In an experiment with 688 undergraduate students, we empirically investigated the effectiveness of three graphical properties of visualizations: area-proportionality, use of discrete and countable statistical entities, and graphical transparency of the nested-sets structure. We found no additional beneficial effect of area-proportionality. In contrast, the representation of discrete objects seems to be beneficial. Furthermore, our results show a strong facilitating effect of making the nested-sets structure of a Bayesian situation graphically transparent. Our results contribute to answering the questions of how and why a visualization could facilitate judgment and decision making in situations of uncertainty. (shrink)

Counter to the popular impression that Adam Smith was a champion of selfishness and greed, Jerry Muller shows that the Inquiry into the Nature and Causes of the Wealth of Nations maintained that markets served to promote the well-being of ...

Coherence in conversations and in texts can be partially characterized by a set of coherence relations, motivated ultimately by the speaker's or writer's need to be understood. In this paper, formal definitions are given for several coherence relations, based on the operations of an inference system; that is, the relations between successive portions of a discourse are characterized in terms of the inferences that can be drawn from each. In analyzing a discourse, it is frequently the case that we would (...) recognize it as coherent, in that it would satisfy the formal definition of some coherence relation, if only we could assume certain noun phrases to be coreferential. In such cases, we will simply assume the identity of the entities referred to, in what might be called a “petty conversational implicature,” thereby solving the coherence and coreference problems simultaneously. Three examples of different kinds of reference problems are presented. In each, it is shown how the coherence of the discourse can be recognized, and how the reference problems are solved, almost as a by‐product, by means of these petty conversational implicatures. (shrink)

Preface 1 Introduction: The Persistence of the Attitudes 2 Individualism and Supervenience 3 Meaning Holism 4 Meaning and the World Order Epilogue Creation Myth Appendix Why There Still Has to be a Language of Thought Notes References Author Index.

At a time when the label "conservative" is indiscriminately applied to fundamentalists, populists, libertarians, fascists, and the advocates of one or another orthodoxy, this volume offers a nuanced and historically informed presentation of ...

Three negative affective dispositions—anger, anxiety, and depression—are hypothesized to increase physical disease risk and have been the subject of epidemiological studies. However, the overlap among the major negative affective dispositions, and the superordinate construct of trait negative affectivity are only beginning to be tested. Presented here is a narrative review of recent prospective studies that simultaneously tested anger, anxiety, depression, and trait NA as risk factors for cardiac outcomes. Anxiety and depression emerged as independent risk factors for premature heart disease (...) in population studies of persons nominally healthy at baseline, and for recurrence/mortality among patients with existing heart disease. General trait NA also was a cardiac risk factor in population samples. (shrink)

This volume is a collection of original contributions about the core knowledge in fundamental domains. It includes work on naive physics, such as formal specifications of intuitive theories of spatial relations, time causality, substance and physical objects, and on naive psychology.

We take it that Brandom’s sense of the geography is that our way of proceeding is more or less the first and his is more or less the second. But we think this way of describing the situation is both unclear and misleading, and we want to have this out right at the start. Our problem is that we don’t know what “you start with” means either in formulations like “you start with the content of words and proceed to the (...) content of sentences” or in formulations like “you start with the content of sentences and you proceed to the content of words.” Brandom’s official view seems to be that he’s talking about explanatory priorities (see the preceding quote); but we think that can’t really be what he has in mind, and we can’t find any alternative interpretation that seems plausible. Speaking just for ourselves, we’re inclined towards a relatively pragmatic view of explanation; what explanation we should “start with” depends, inter alia, on what it’s an explanation of and whom it’s an explanation for. But, in any case, we would have thought that explanatory priority is of more than heuristic interest only if it reflects a priority of some other kind: ontological, semantical, psychological, or whatever. In talking about what one “starts with”, Brandom must be claiming more than. (shrink)

The renowned philosopher Jerry Fodor, a leading figure in the study of the mind for more than twenty years, presents a strikingly original theory on the basic constituents of thought. He suggests that the heart of cognitive science is its theory of concepts, and that cognitive scientists have gone badly wrong in many areas because their assumptions about concepts have been mistaken. Fodor argues compellingly for an atomistic theory of concepts, deals out witty and pugnacious demolitions of rival theories, (...) and suggests that future work on human cognition should build upon new foundations. This lively, conversational, and superbly accessible book is the first volume in the Oxford Cognitive Science Series, where the best original work in this field will be presented to a broad readership. Concepts will fascinate anyone interested in contemporary work on mind and language. Cognitive science will never be the same again. (shrink)

This study synthesizes current information from the various fields of cognitive science in support of a new and exciting theory of mind. Most psychologists study horizontal processes like memory and information flow; Fodor postulates a vertical and modular psychological organization underlying biologically coherent behaviors. This view of mental architecture is consistent with the historical tradition of faculty psychology while integrating a computational approach to mental processes. One of the most notable aspects of Fodor's work is that it articulates features not (...) only of speculative cognitive architectures but also of current research in artificial intelligence. (shrink)

I agree with the commentators that study of physical disease risk conferred by affective dispositions such as anger/hostility, anxiety, and sadness, should be more cognizant of developments in emotion theory. Emotions differ in their functional value depending on the person’s lifespan trajectory. Discrete emotions have different psychophysiological signatures; and emotional competence, including production, regulation, and knowledge, may be critical in determining whether specific negative affects, or general negative affectivity, are toxic for physical health. Emotion researchers, however, have mainly focused on (...) acute affective experiences and ignored the general effects of negative affectivity, which subsumes the discrete negative affects. Most diseases develop over years so more needs to be known about the biological signatures of chronic specific affects and negative affectivity. (shrink)

Introduction: Something on the State of the Art 1 I. Functionalism and Realism 1. Operationalism and Ordinary Language 35 2. The Appeal to Tacit Knowledge in Psychological Explanations 63 3. What Psychological States are Not 79 4. Three Cheers for Propositional Attitudes 100 II. Reduction and Unity of Science 5. Special Sciences 127 6. Computation and Reduction 146 III. Intensionality and Mental Representation 7. Propositional Attitudes 177 8. Tom Swift and His Procedural Grandmother 204 9. Methodological Solipsism Considered as a (...) Research Strategy in Cognitive Psychology 225 IV. Nativism 10. The Present Status of the Innateness Controversy 257 Notes 317. (shrink)

A notable feature of paradox is recognition that seemingly contradictory terms are inextricably intertwined and interrelated—holding out the hope that something new can be learned from the cognitive tension contained within. Aram has characterized the central concern of the business and society field as the paradox of interdependent relations. Our study argues that this and related paradoxes can be addressed by engaging with others and trying to gain shared insight via an interactive, developmental, exploratory sensemaking process that can inform the (...) governance of stakeholder networks. We advocate multistakeholder learning dialogues (MSLDs) as a means for both scholars and practitioners to construct meanings that can guide joint efforts to cope with messy problems that help shape complex, paradoxical relationships within stakeholder networks. (shrink)

Jerry L. Walls aims to demonstrate in his book Hell: The Logic of Damnation that some traditional views of hell are still defensible and can be believed with intellectual and moral integrity. Focusing on the issues from the standpoint of philosophical theology, Walls explores the doctrine of hell in relation to both the divine nature and human nature. He argues, with respect to the divine nature, that some traditional versions of the doctrine are compatible not only with God's omnipotence (...) and omniscience, but also with a strong account of His perfect goodness. The concept of divine goodness receives special attention since the doctrine of hell is most often rejected on moral grounds. (shrink)

The class of geometric surgical theories is examined. The main theorem is that every stable theory that is interpretable in a geometric surgical theory is superstable of finite U-rank.

In this paper, planning models developed in artificial intelligence are applied to the kind of planning that must be carried out by participants in a conversation. A planning mechanism is defined, and a short fragment of a free‐flowing videotaped conversation is described. The bulk of the paper is then devoted to an attempt to understand the conversation in terms of the planning mechanism. This microanalysis suggests ways in which the planning mechanism must be augmented, and reveals several important conversational phenomena (...) that deserve further investigation. (shrink)

The rich body of physical theories defines the foundation of our understanding of the world. Its mathematical formulation is based on classical Aristotelian logic. In the philosophy of science the ambiguities, paradoxes, and the possibility of subjective interpretations of facts have challenged binary logic, leading, among other developments, to Gotthard Günther’s theory of polycontexturality. Günther’s theory explains how observers with subjective perception can become aware of their own subjectivity and provides means to describe contradicting or even paradox observations in a (...) logically sound formalism. Here we summarize the formalism behind Günther’s theory and apply it to two well-known examples from physics where different observers operate in distinct and only locally valid logical systems. Using polycontextural logic we show how the emerging awareness of these limitations of logical systems entails the design of mathematical transformations, which then become an integral part of the theory. In our view, this approach offers a novel perspective on the structure of physical theories and, at the same time, emphasizes the relevance of the theory of polycontexturality in modern sciences. (shrink)

In Brazil, the country with the largest population of African descent in the Americas, the idea of race underwent a dramatic shift in the first half of the twentieth century. Brazilian authorities, who had considered race a biological fact, began to view it as a cultural and environmental condition. Jerry Dávila explores the significance of this transition by looking at the history of the Rio de Janeiro school system between 1917 and 1945. He demonstrates how, in the period between (...) the world wars, the dramatic proliferation of social policy initiatives in Brazil was subtly but powerfully shaped by beliefs that racially mixed and nonwhite Brazilians could be symbolically, if not physically, whitened through changes in culture, habits, and health. Providing a unique historical perspective on how racial attitudes move from elite discourse into people’s lives, _Diploma of Whiteness_ shows how public schools promoted the idea that whites were inherently fit and those of African or mixed ancestry were necessarily in need of remedial attention. Analyzing primary material—including school system records, teacher journals, photographs, private letters, and unpublished documents—Dávila traces the emergence of racially coded hiring practices and student-tracking policies as well as the development of a social and scientific philosophy of eugenics. He contends that the implementation of the various policies intended to “improve” nonwhites institutionalized subtle barriers to their equitable integration into Brazilian society. (shrink)

One of the most notable aspects of Fodor's work is that it articulates features not only of speculative cognitive architectures but also of current research in ...

This paper explores the difference between Connectionist proposals for cognitive a r c h i t e c t u r e a n d t h e s o r t s o f m o d e l s t hat have traditionally been assum e d i n c o g n i t i v e s c i e n c e . W e c l a i m t h a t t h (...) e m a j o r d i s t i n c t i o n i s t h a t , w h i l e b o t h Connectionist and Classical architectures postulate representational mental states, the latter but not the former are committed to a symbol-level of representation, or to a ‘language of thought’: i.e., to representational states that have combinatorial syntactic and semantic structure. Several arguments for combinatorial structure in mental representations are then reviewed. These include arguments based on the ‘systematicity’ of mental representation: i.e., on the fact that cognitive capacities always exhibit certain symmetries, so that the ability to entertain a given thought implies the ability to entertain thoughts with semantically related contents. We claim that such arguments make a powerful case that mind/brain architecture is not Connectionist at the cognitive level. We then consider the possibility that Connectionism may provide an account of the neural (or ‘abstract neurological’) structures in which Classical cognitive architecture is implemented. We survey a n u m b e r o f t h e s t a n d a r d a r g u m e n t s t h a t h a v e b e e n o f f e r e d i n f a v o r o f Connectionism, and conclude that they are coherent only on this interpretation. (shrink)

Preface and Acknowledgments Introduction PART I Intentionality Chapter 1 Fodor’ Guide to Mental Representation: The Intelligent Auntie’s Vade-Mecum Chapter 2 Semantics, Wisconsin Style Chapter 3 A Theory of Content, I: The Problem Chapter 4 A Theory of Content, II: The Theory Chapter 5 Making Mind Matter More Chapter 6 Substitution Arguments and the Individuation of Beliefs Chapter 7 Stephen Schiffer’s Dark Night of The Soul: A Review of Remnants of Meaning PART II Modularity Chapter 8 Précis of The Modularity of (...) Mind Chapter 9 Why Should the Mind Be Modular? Chapter 10 Observation Reconsidered Appendix: A Reply to Churchland’s ‘Perceptual Plasticity and Theoretical Neutrality" References Index of Names. (shrink)

Weeter and Duvall were good friends and philosophical colleagues. Their friendship was served by the fact that they shared a number of important philosophical commitments. Both, for instance, were theists. Both also devoutly believed in possible worlds, propositions, and essences. And furthermore, both were ardent libertarians.

Joseph Blado critiqued my probabilistic arguments against Roman papal doctrines by deploying probability arguments, particularly Bayesian arguments, in favor of the papacy. He contends that there are good C-inductive arguments for papal doctrine that, taken together, add up to a good P-inductive argument. I argue that his inductive arguments fail, and moreover that there are three good C-inductive arguments against papal doctrine in the neighborhood of his failed arguments. I conclude by critiquing his retreat to what he calls ‘skeptical papalism’ (...) as a last ditch sort of move to defend papal doctrine. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Reviewed by:A Secular AgeJerry WallulisA Secular Age by Charles Taylor. Cambridge, Mass.: Harvard University Press, 2007. Pp. x + 874. $39.95, cloth.It is almost a philosophical truism that the phenomenologist who is able to see more in the phenomenon will be wise to do so. While Charles Taylor may not explicitly advocate such a truism in The Secular Age, he is adamantly opposed to "subtraction stories" regarding the secularization (...) process in modern Western societies. His alternative narrative involves "seeing" a meaning to secularity that is deeper and truer to the past and present lived experience of both believers and nonbelievers. The length of that narrative (800+ pages) is obviously demanding but also arguably rewarding—even to the philosophical or social theoretical temperament initially inclined to see less in the process.A "subtraction story" of secularization describes the transition to modernity in terms of discarding or outgrowing a framework of beliefs that typically is viewed as an impediment. Such a story is normally situated within the context of one of the two most recognized meanings of "secularity." The first of these meanings involves freeing modern political organizations and other forms of public life from explicit connections to religious beliefs and institutions. The second meaning refers to a decline in religious belief and practice as measured, for example, in falling church attendance. Particularly with respect to the second meaning, a subtraction story is likely to attribute secularity to progress in scientific and normative inquiry that supplants and even replaces earlier religious thinking, action, and politics. [End Page 302]The third and deeper meaning of secularity involves what Taylor terms the "conditions of belief." The whole context of understanding what it is to believe has changed in the past five hundred years "from a society in which it was virtually impossible not to believe in God, to one in which faith, even for the staunchest believer, is one human possibility among others" (3). For Taylor this momentous transition is misunderstood as a subtraction process in contrast to a richer historical tracing of the sources of meaningful belief and unbelief. According to this rival account, religious belief continues and alters, even as a strong alternative to faith emerges ("exclusive humanism") but also, and equally, a plenitude (or "nova") of intermediate views or human possibilities.The dramatic change in the conditions of belief is accompanied by an equally marked historical shift in the situation of the self that is experiencing this transition. After the change a clear distinction is made between the mind and the body and between the self and the world. The strong distinctions between the "mental" and the "physical" and the "subjective" and the "objective" serve to mark firm boundaries in our experience. These boundaries function as "buffers" so that things that go beyond our mental states and subjective feelings do not need to cross over and upset or disorient us.For Taylor the premodern situation of the self was not characterized by firm boundaries but rather by "porous" ones. The difference is that the inside of earlier lived experience was neither just inside nor cordoned off from the outside of experience. Thus a powerful emotion was not limited to mind or self but was porous to the influence of outside powers that boded well or ill. Indeed the force of such outside things could be experienced as so strong and the vulnerability of the self so great as to make urgent the need for propitiation of or defense against a friendly or evil spiritual power.The transition from enchantment to disenchantment is not simply a change in beliefs, but in sensibilities within lived experience that affect what it is to believe. We find enchantment so difficult to comprehend because we are "buffered selves" who are open to kinds of meanings with clearly delineated boundaries. Earlier "porous selves" were open, by contrast, to the possibility of being dominated by a spirit or being taken over by a medium. Disbelief is difficult to imagine for porous selves, since "God figures in this world as the dominant spirit, and moreover, as the only thing that guarantees that in this awe-inspiring and frightening field of forces, good will triumph" (41... (shrink)

John Wesley explained the existence of evil in moral rather than metaphysical terms. His understanding of the fall was fairly typical of western theology and he also enthusiastically embraced a version of the felix culpa theme as essential for theodicy. Unlike many influential western theologians, he also relied heavily on libertarian freedom to account for evil. His most striking proposal for theodicy involves his eschatalogical vision of the future in which he believed the entire world living then will be converted. (...) I argue that his theodicy is implicitly universalist, especially in its eschatalogical speculations, and show that this is in tension with his strong libertariancommitments. (shrink)

Whether you play basketball, coach it, or just love to watch it, this book will forever enrich your understanding and appreciation of the game.

The quality of working life and the quality of business ethics cannot be separated. In the private sector, the profit priority motivates most employer behavior, which can be characterized as mean and rationalistic. Management-initiated quality of life programs are usually disguised attempts to achieve a speedup. From the union perspective, fair wages and working conditions are synonymous with the quality of working life, and unions pursue these through collective bargaining, which is essentially adversarial in both the public and private sectors. (...) AFSCME's approach is to negotiate for better staffing, career ladders, and other workplace improvements that contribute to a worker's sense of dignity and satisfaction. (shrink)

In a recent exchange on the subject of Columbo, Agnes Heller and Moishe Gonzales pitched their tents within the landscape of popular culture which was already littered with the remnants of various academic approaches to the culture industry. Neither, however, went far enough in defetishizing this icon of popular culture and, as a consequence, do not penetrate its sinister qualities. Heller in particular attempts to write a contemporary theory of history based on Columbo, but her hope of raising a counterfeit (...) product of the culture industry to Utopian heights is doomed to failure. The secret of Columbo lies in the fact that he has been plagiarized from an older, more authentic cultural critique. (shrink)

This study examines whether the gender of the directors on fully independent audit committees affects the ability of the committees in constraining earnings management and thus their effectiveness in overseeing the financial reporting process. Using a sample of 525 firm-year observations over the period 2003 to 2005, we are unable to identify an association between the proportion of female directors on audit committees and the extent of earnings management.

Jerry L. Walls argues that the doctrine of heaven is ripe for serious reconsideration. He contends not only that the orthodox view of heaven can be defended from objections commonly raised against it, but also that heaven is a powerful resource for addressing persistent philosophical problems, not the least of which concern the ground of morality and the meaning of life. Walls shows how heaven is integrally related to central Christian doctrines, particularly those related to salvation, and tackles the (...) difficult problem of why faith in Christ is necessary to save us from our sins. In addition, heaven is shown to illumine thorny problems of personal identity and to be an essential component of a satisfactory theodicy. Walls goes on to examine data from near-death experiences from the standpoint of some important recent work in epistemology and argues that they offer positive evidence for heaven. He concludes that we profoundly need to recover the hope of heaven in order to recover our very humanity. (shrink)

Jerry Fodor argues against the widely held view that mental processes are largely computations, that the architecture of cognition is massively modular, and...

Most people know precious little about the risks and benefits of participating in a clinical trial--a medical research study involving some innovative treatment for a medical problem. Yet millions of people each year participate anyway. Patients at Risk explains the reality: that our current system intentionally hides much of the information people need to make the right choice about whether to participate. Witness the following scenarios: -Hundreds of patients with colon cancer undergo a new form of keyhole surgery at leading (...) cancer centersnever -Tens of thousands of women at high risk of developing breast cancer are asked to participate in a major research study. They are told about the option of having both breasts surgically removed but not told about the option of taking a standard osteoporosis pill that might cut the risk of getting breast cancer by one-half or more. Patients at Risk written by two nationally prominent experts, is the first book to reveal the secrets that many in the research establishment have fought long and hard to keep from patients. It shows why options not commonly knownincluding getting a new treatment outside of a research studycan often be the best choice. It explains how patients can make good decisions even if there is only limited information about a treatments effect. And it does this through the eye-opening stories of what is happening daily to thousands of people. Day after day, we are learning how little we know about what really works. Headlines regularly announce that a previously unquestioned treatmenthormone replacement therapy, drugs such as Vioxx or Celebrexmay now be much riskier than we thought. The latest book in a surge of recent books criticizing the medical establishment (but the first to look at clinical trials specifically), Patients at Risk helps to empower patients to survive in a world of medical uncertainty, and makes positive recommendations for systemic reform. (shrink)

n 1902, 70 million years after it tripped lightly through the Mesozoic forests in search of meat, the skeleton of a 20-foothightyrannosaurus was dynamited out of a sandstone bluff near Hell Creek, Mont. Wrapped in burlap and plaster and shipped back to New York, the bones were painstakingly reassembled by fossil curator Barnum Brown of the American Museum of Natural History. It was there, one day in 1947, that they happened to scare the bejesus out of 5-year-old Stephen Jay Gould. (...) With a mouthful of teeth as big as bananas, the great reptile gaped down at the little mammal who had usurped its place at the head of the food chain and set him scurrying for the safety of his daddy's pant leg. It was a sublime epiphany. Long after Gould could stare with equanimity at the skull of tyrannosaurus, he was left with the essential mystery that still motivates him as perhaps America's foremost writer and thinker on evolution: why should dinosaurs have ended up in human museums instead of—as one among an infinite number of evolutionary possibilities—the other way around? (shrink)

Jerry Fodor presents a new development of his famous Language of Thought hypothesis, which has since the 1970s been at the centre of interdisciplinary debate about how the mind works. Fodor defends and extends the groundbreaking idea that thinking is couched in a symbolic system realized in the brain. This idea is central to the representational theory of mind which Fodor has established as a key reference point in modern philosophy, psychology, and cognitive science. The foundation stone of our (...) present cognitive science is Turing's suggestion that cognitive processes are not associations but computations; and computation requires a language of thought. So the latest on the Language of Thought hypothesis, from its progenitor, promises to be a landmark in the study of the mind. LOT 2 offers a more cogent presentation and a fuller explication of Fodor 's distinctive account of the mind, with various intriguing new features. The central role of compositionality in the representational theory of mind is revealed: most of what we know about concepts follows from the compositionality of thoughts. Fodor shows the necessity of a referentialist account of the content of intentional states, and of an atomistic account of the individuation of concepts. Not least among the new developments is Fodor 's identification and persecution of pragmatism as the leading source of error in the study of the mind today. LOT 2 sees Fodor advance undaunted towards the ultimate goal of a theory of the cognitive mind, and in particular a theory of the intentionality of cognition. No one who works on the mind can ignore Fodor 's views, expressed in the coruscating and provocative style which has delighted and disconcerted countless readers over the years. (shrink)

hroughout medieval Christianity, religious works of art emerged to illustrate the teachings of the Bible for the largely illiterate population. What, then, is the significance of the psychoactive mushrooms hiding in plain sight in the artwork and icons of many European and Middle-Eastern churches? Does Christianity have a psychedelic history? -/- Providing stunning visual evidence from their anthropological journey throughout Europe and the Middle East, including visits to Roslyn Chapel and Chartres Cathedral, authors Julie and Jerry Brown document the (...) role of visionary plants in Christianity. They retrace the pioneering research of R. Gordon Wasson, the famous “sacred mushroom seeker,” on psychedelics in ancient Greece and India, and among the present-day reindeer herders of Siberia and the Mazatecs of Mexico. Challenging Wasson’s legacy, the authors reveal his secret relationship with the Vatican that led to Wasson’s refusal to pursue his hallucinogen theory into the hallowed halls of Christianity. -/- Examining the Bible and the Gnostic Gospels, the authors provide scriptural support to show that sacred mushrooms were the inspiration for Jesus’ revelation of the Kingdom of Heaven and that he was initiated into these mystical practices in Egypt during the Missing Years. They contend that the Trees of Knowledge and of Immortality in Eden were sacred mushrooms. -/- Uncovering the role played by visionary plants in the origins of Judeo-Christianity, the authors invite us to rethink what we know about the life of Jesus and to consider a controversial theory that challenges us to explore these sacred pathways to the divine. (shrink)