In this open peer commentary, we categorize the possible “neuroscience in national security” definitions of misuse of science and identify which, if any, are uniquely presented by advances in neuroscience. To define misuse, we first define what we would consider appropriate use: the application of reasonably safe and effective technology, based on valid and reliable scientific research, to serve a legitimate end. This definition presents distinct opportunities for assessing misuse: misuse is the application of invalid or unreliable science, or is (...) the use of reliable scientific methods to serve illegitimate ends. Ultimately, we conclude that while national security is often a politicized issue, assessing the state of scientific progress should not be. (shrink)

The current informal practice of pharmacometrics as a combination art and science makes it hard to appreciate the role that informatics can and should play in the future of the discipline and to comprehend the gaps that exist because of its absence. The development of pharmacometric informatics has important implications for expediting decision making and for improving the reliability of decisions made in model-based development. We argue that well-defined informatics for pharmacometrics can lead to much needed improvements in the efficiency, (...) effectiveness, and reliability of the pharmacometrics process. The purpose of this paper is to provide a description of the pervasive yet often poorly appreciated role of informatics in improving the process of data assembly, a critical task in the delivery of pharmacometric analysis results. First, we provide a brief description of the pharmacometric analysis process. Second, we describe the business processes required to create analysis-ready data sets for the pharmacometrician. Third, we describe selected informatic elements required to support the pharmacometrics and data assembly processes. Finally, we offer specific suggestions for performing a systematic analysis of existing challenges as an approach to defi ning the next generation of pharmacometric informatics. (shrink)

In The Foundations of Arithmetic, Gottlob Frege contended that the difference between concepts and objects was absolute. He meant that no object could be a concept and no concept an object. Benno Kerry disagreed; he contended that a concept could be an object, and that therefore the difference between concepts and objects was only relative. In this book, Jolley aims to understand the debate between Frege and Kerry. But Jolley's purpose is not so much to champion either side; rather, it (...) is to utilize an understanding of the debate to shed light on the work of Ludwig Wittgenstein-and vice versa. Jolley not only sifts through the debate between Frege and Kerry, but also through subsequent versions of the debate in J. J. Valberg and Wilfred Sellars. Jolley's goal is to show that the central notion of Philosophical Investigations, that of a 'conceptual investigation', is a legacy of the Frege/Kerry debate and also a contribution to it. Jolley concludes that the difference between concepts and objects is as absolute in its way in Philosophical Investigations as it was in The Foundations of Arithmetic and that recognizing the absoluteness of the difference in Philosophical Investigations provides a beginning for a 'resolute' reading of Wittgenstein's book. (shrink)

I certainly find it easier to recognize the deep continuities within Wittgenstein's thought, than the real nature of the contrasts: one only comes to recognize these for what they are after prolonged engagement with the two works.Heather Gert has offered a reading of Investigations §§ 46-50. Her attention devolves primarily on the notorious standard meter paragraph of § 50. Important to her reading is her conviction about what it is from the Tractatus that is being criticized and about how it (...) is being criticized.I believe Gert's reading of the passage is mistaken. Gert fails to get fully into focus what is happening in the distance, in the Tractatus, and she fails to get into focus what is happening nearby, in .. (shrink)

What follows is talky—I skitter across a number of difficult topics much too quickly and with little attempt to defend what I say. I may be able to add some defense later in discussion, but I don't promise anything much and certainly nothing fancy. I am still very much in the process of thinking about these topics, and I aim to do no more than to perhaps nudge you to think about them too.By "poetry" in what follows, I typically mean (...) "lyric poetry." There are poems and poems and poems, and the dactyls make a difference, as do many other features internal to poetry. I will also say upfront that I have no working definition of "lyric poetry." I also have no working definition of "philosophy," although I will be... (shrink)

Peter Kivy investigates the unity of form and content in the arts, particularly in poetry. While Kivy says much with which I happily agree, I sadly disagree with him about the impossibility of form–content identities. Kivy's arguments fail to compel: there are other ways of understanding form–content identities and the need for them that has been felt by artists and critics. CiteULike Connotea Del.icio.us What's this?

This book brings together a team of leading theorists to address the question 'What is the right measure of justice?' Some contributors, following Amartya Sen and Martha Nussbaum, argue that we should focus on capabilities, or what people are able to do and to be. Others, following John Rawls, argue for focussing on social primary goods, the goods which society produces and which people can use. Still others see both views as incomplete and complementary to one another. Their essays evaluate (...) the two approaches in the light of particular issues of social justice - education, health policy, disability, children, gender justice - and the volume concludes with an essay by Amartya Sen, who originated the capabilities approach. (shrink)

Abstract: In this article I contest a reading of Wittgenstein's Philosophical Investigations —a reading of it as debunking philosophy. I concede that such a reading is not groundless, but I show why it is nonetheless mistaken. To do so, I distinguish two different ways of viewing Philosophical Investigations and its concern with philosophical problems, an External View and an Internal View. On the External View, readers of the book are taken to know ahead of time what philosophical problems are. On (...) the Internal View, readers are not taken to know this ahead of time: the task of the book is to disclose what philosophical problems are, to show them coming into being. One thing disclosed is our participatory role in philosophical problems coming to be. Learning about the nature of philosophical problems is thus learning about our own nature; metaphilosophical knowledge is in part self-knowledge. If the Internal View is correct (as I believe it is), then Philosophical Investigations does not debunk philosophy but provides a different conception of philosophy and the philosopher's task. (shrink)

In this essay, I respond to A. W. Moore’s instructive chapter on Frege. I respond by asking various questions, and I question particularly Moore’s claim that Frege, in reacting to Benno Kerry, falls into Hegelian excess. I toy with responding to my question by regarding Frege as anticipating a Wittgensteinian-Heideggerian exaction. It remains unclear whether this constitutes (much) progress.

In the dissertation I explore three central issues in Plotinus' philosophical psychology: The fall of the soul, the relationships of soul and body, and the concept of the ego. ;Chapter 1 introduces the issues. Chapter 2 argues for a dual-aspect theory about the soul's fall. Chapter 3 characterizes the relationships between soul and body. Much of the chapter is devoted to distancing Plotinus' dualism from Cartesian dualism. The chapter ends with a discussion of Plotinus on perception. Chapter 4 investigates the (...) concept of the ego, the function of the ego in union with the One, and the relationship between the ego and the other powers of the soul. (shrink)

What is it to read Wittgenstein resolutely? In this essay, I make a suggestion about how to answer that question. I backtrack in time to a debate about Philosophical Investigations between O. K. Bouwsma and Gilbert Ryle. I selectively reconstruct that debate, highlighting features of it that I take to be interesting in their own right and in relation to debates about PI, but also interesting in analogy with debates about resolute and standard readings of Tractatus logico-philosophicus. As will be (...) clear, my sympathies are with Bouwsma against Ryle, and with resolute readers against standard readers. But I do not vindicate Bouwsma; I will, in fact, be critical, carefully or guardedly critical of him.Nor do I vindicate resolute reading of TLP. I suggest a way of seeing resolute reading that makes clearer what it is and how it contrasts with standard reading, and, in so doing, that makes clearer what some of the difficulties of the debate between the readings really are, whether about TLP or about PI. (shrink)

In this essay I investigate the unity of Emerson's sentences. I begin by describing the phenomenology of reading Emerson and use that phenomenology to orient the investigation. I propose to understand the unity of Emerson's sentences by using a variation of Frege's strategy for understanding the unity of sentences generally. I then address how the unity of the Emerson sentence serves to create the unity of the Emerson paragraph and even of the Emerson essay. Along the way I compare Emerson's (...) essays to Lancelot Andrewes’ sermons. I finish by using the results of the investigation and comparisons to provide a partial reading of “Experience” in which I shed light on the nature of Emerson's encounter with the problematic of skepticism. (shrink)

In this essay, we focus primarily on Moore’s “Proof of an External World” and Kant’s “Refutation of Idealism.” We are not exactly commenting on Clarke’s “The Legacy of Skepticism,” interpreting it, although what we do involves us in (some of) that. Instead of directly commenting on it, we do things with Legacy; we read Moore’s Proof and Kant’s Refutation with Clarke in mind. And by way of doing this, we bring onto the stage a post-Legacy Moore, and a post-Legacy Kant. (...) We do not claim to present Moore and Kant per se (to use Clarke’s term); we do not portray Moore and Kant as they are independently of “The Legacy of Skepticism.” We propose instead Moore and Kant as we read them after Legacy, i.e., in light of the pure/plain distinction. (shrink)

The concepts of animal, human, and rights are all part of a philosophical tradition that trades on foreclosing the animal, animality, and animals. Rather than looking to qualities or capacities that make animals the same as or different from humans, I investigate the relationship between the human and the animal. To insist, as animal rights and welfare advocates do, that our ethical obligations to animals are based on their similarities to us reinforces the type of humanism that leads to treating (...) animals—and other people—as subordinates. But, if recent philosophies of difference are any indication, we can acknowledge difference without acknowledging our dependence on animals, or without including animals in ethical considerations. Animal ethics requires rethinking both identity and difference by focusing on relationships and responsivity. My aim is not only to suggest an animal ethics but also to show how ethics itself is transformed by considering animals. (shrink)

This book is a tribute to Kevin Kelly, who has been one of the most influential British theologians for a number of decades. On its own merits, however, it is groundbreaking collection of essays on key themes, issues and concepts in contemporary moral theology and Christian ethics. The focus is on perspectives to inform moral debate and discernment in the future. The main themes covered are shown in the list of contents below. Several of the of the contributors are (...) from the United States, three others live and work in Continental Europe and the rest are from various parts of the British Isles. Many of the authors are among the best known in their fields on both sides of the Atlantic. (shrink)

These posthumous essays by Joan Kelly, a founder of women's studies, represent a profound synthesis of feminist theory and historical analysis and require a realignment of perspectives on women in society from the Middle Ages to the present.

“The bandages signify death,” says Derrida, “the condemnation to death; when they fall away, out of use, undone, untied, untying, they signify, like a detached signifier, that the dead one is resuscitated." Like a detached signifier, indicating a metaphorical relationship between signification and the bandages. But, when we follow the metonymy of bandages in Derrida’s Death Penalty seminar volume one, the bandages appear as the figure for figuration itself. More specifically, they are a sign that needs interpretation; a sign that (...) the bandages are detached from the body; a sign that the word, or sign, is detached from the thing. (shrink)

Between the Psyche and the Social is the first collection that specifically features the field of psychoanalytic social theory emerging in and between psychoanalysis, feminism, postcolonial studies, and queer theory, and across the disciplines of philosophy, literary, film, and cultural studies. This collection of essays takes the psychoanalytic study of social oppression in some new directions by engaging—indeed, stirring up—unconscious fantasies and ethical tensions at the heart of social subjectivity.