Studia Tibetica et Mongolica. Redigenda curaverunt Helmut Eiger, Michael Hahn, Maria Schetelich et Peter Wyzlic., Indica et Tibetica Verlag, Swisttal-Odendorf 1999. xxix, 346 pp. ISBN 3-923776-34-9.

This chapter contains sections titled: Introduction A Brief History of Developmental Explanations of Phenotypic Evolution Research Questions of Evo‐Devo Unifying Themes of the Conceptual Basis of Evo‐Devo Conclusion: A Mechanistic Theory of Evo‐Devo Challenges the Modern Synthesis Postscript: Counterpoint References.

The biological sciences have become increasingly reliant on so-called ‘model organisms’. I argue that in this domain, the concept of a descriptive model is essential for understanding scientific practice. Using a case study, I show how such a model was formulated in a preexplanatory context for subsequent use as a prototype from which explanations ultimately may be generated both within the immediate domain of the original model and in additional, related domains. To develop this concept of a descriptive model, I (...) focus on use of the nematode worm Caenorhabditis elegans and the wiring diagrams that were developed as models of its neural structure. In addition, implications of the concept of a descriptive model, particularly its relevance for the data-phenomena distinction as well as its relation to long-standing debates on realism, are briefly examined. (shrink)

COVID-19 has revealed that science needs to learn how to better deal with the irreducible uncertainty that comes with global systemic risks as well as with the social responsibility of science towards the public good. Further developing the epistemological principles of new theories and experimental practices, alternative investigative pathways and communication, and diverse voices can be an important contribution of history and philosophy of science and of science studies to ongoing transformations of the scientific enterprise.

In this paper we argue that an operational organism concept can help to overcome the structural deficiency of mathematical models in biology. In our opinion, the structural deficiency of mathematical models lies mainly in our inability to identify functionally relevant biological characters in biological systems, and not so much in a lack of adequate mathematical representations of biological processes. We argue that the problem of character identification in biological systems is linked to the question of a properly formulated organism concept. (...) Lastly, we demonstrate how a decomposition of an organism into independent characters in the context of a specific biological process--such as adaptation by means of natural selection--depends on the dynamical properties and invariance conditions of the equations that describe this process. (shrink)

Biology lacks a central organism concept that unambiguously marks the distinction between organism and non-organism because the most important questions about organisms do not depend on this concept. I argue that the two main ways to discover useful biological generalizations about multicellular organization—the study of homology within multicellular lineages and of convergent evolution across lineages in which multicellularity has been independently established—do not require what would have to be a stipulative sharpening of an organism concept.

In this paper we argue that an operational organism concept can help to overcome the structural deficiency of mathematical models in biology. In our opinion, the structural deficiency of mathematical models lies mainly in our inability to identify functionally relevant biological characters in biological systems, and not so much in a lack of adequate mathematical representations of biological processes. We argue that the problem of character identification in biological systems is linked to the question of a properly formulated organism concept. (...) Lastly, we demonstrate how a decomposition of an organism into independent characters in the context of a specific biological process—such as adaptation by means of natural selection—depends on the dynamical properties and invariance conditions of the equations that describe this process. (shrink)

Foreword The collection of research papers in this book is a selection made from those which were presented at the eighth conference of the International ...

Caenorhabditis elegans is a tiny worm that has become the focus of a large number of worldwide research projects examining its genetics, development, neuroscience, and behavior. Recently several groups of investigators have begun to tie together the behavior of the organism and the underlying genes, neural circuits, and molecular processes implemented in those circuits. Behavior is quintessentially organismal—it is the organism as a whole that moves and mates—but the explanations are devised at the molecular and neurocircuit levels, and tested in (...) populations using protocols that span many levels of aggregation. Following a brief review of the main relevant features of C. elegans, I describe some of these circuits, and then discuss two contrasting approaches in behavioral genetics and neural network analysis of the worm. Finally, I outline the rudiments of a “field and focus” explanation model using the two contrasting approaches. (shrink)

Inhalt: Thomas Sören HOFFMANN: »… eine besondere Weise, sich selbst zu erblicken«: Zum systematischen Status der Natur nach Fichte. Christian STADLER: Der Transzendentalphilosophische Rechtsbegriff und seine systematische Begründungsleistung. Katja V. TAVER: Fichte und Arnold Gehlen. Fichtes Philosophie des Rechts von 1796 und 1812 im Fokus von Arnold Gehlens philosophischer Anthropologie. Jean-Christophe MERLE: Fichtes Begründung des Strafrechts. Manfred GAWLINA: Verhalten als Synthesis von Recht und Gesinnung. Zur Auseinandersetzung zwischen Kant, Fichte und Hegel. Carla DE PASCALE: Fichte und die Gesellschaft. Carla (...) AMADIO: Die Logik der politischen Beziehung. Christiana SENIGAGLIA: Die Bestimmung des Bürgers beim späten Fichte. Ferenc L. LENDVAI: Stellung und Spuren einer Sozialethik in Fichtes Philosophie. Teil I: Die Stellung einer Sozialethik in Fichtes Philosophie. Judit HELL: Stellung und Spuren einer Sozialethik in Fichtes Philosophie. Teil II: Die Spuren einer Sozialethik in Fichtes Philosophie. Wladimir Alexejevic ABASCHNIK: Das Konzept des geschlossenen Handelsstaates Fichtes in der Rezeption von Vassilij Nasarovic Karasin. Karl HAHN: Die Relevanz der Eigentumstheorie Fichtes im Zeitalter der Globalisierung unter Berücksichtigung Proudhons und Hegels. Hans HIRSCH: Fichtes Planwirtschaftsmodell als Dokument der Geistesgeschichte und als bleibender Denkanstoß. (shrink)

What happens when collectivity and law intersect? Lisa Hahn and Markus Hasl outline the state of research on this question and add new answers offered by this special issue. On the one hand, the search for interdisciplinary encounters shows that law is both means and object of collective legal struggles. In doing so, collectives shape law. On the other hand, law (re)produces collectives through categorization and personalization; it juridifies. In doing so, it oscillates between productivity and destructiveness. The authors (...) conclude that to advance the productive potential of collectivity and better regulate its risks, theoretical and doctrinal innovations are needed. (shrink)

Sind Wissenschaften und Universitäten (noch) gesellschaftlich und politisch relevant? Die Beiträge dieses Bandes setzen sich mit den politischen Voraussetzungen und Implikationen der wissenschaftlichen Arbeit auseinander und plädieren für die Wahrnehmung gesellschaftlicher Verantwortung durch Wissenschaft und Universität.