Herein is provided a brief overview of agent-based modeling , with a particular slant toward its potential as a tool for the theoretical biologist. Of course, its use for experimentalists is obvious; they are, as a group, already using agent-based models to examine contemporary biological questions ranging from molecular processes to evolving ecological landscapes . For the modeler-theoretician, ABMs offer a new tool for thinking about the structure of biological processes, thus creating a conduit for integrative perspective taking between the (...) experimentalist and the theoretician. (shrink)

Ioannidis [Why most published research findings are false. PLoS Med 2: e124 ] identifies six factors that contribute to explaining why most of the current published research findings are more likely to be false than true, and argues that for many current scientific fields, claimed research findings may often be simply accurate measures of the prevailing bias. In this article, we argue that three “hot” areas in current biological research, viz., agent-based modeling, evolutionary developmental biology , and systems biology, are (...) especially prone to the flaws. (shrink)

This book sorts out the confusion created by the use of the term "postmodern" in relation to widely divergent theological positions. Four different types of postmodern theology are distinguished in the preface: constructive, deconstructive, liberationist, and conservative. Two forms of each type are discussed in the book. Writing from a constructive, postmodern perspective, the authors enter into dialogue with the deconstructive postmodernism of Mark C. Taylor and Jean-François Lyotard, with the liberationist postmodernism of Harvey Cox and Cornel West, and with (...) the conservative postmodernism of George William Rutler and John Paul II. (shrink)

We believe that clinical ethics consultants (CECs) should offer advice, options, and recommendations to attending physicians and their teams. In their article in this issue of The Journal of Clinical Ethics, however, Kornfeld and Prager give CECs a somewhat different role. The CEC they describe may at times be more aptly understood as a medical interventionist who appropriates the roles of the attending physician and the medical team than as a traditional CEC. In these remarks, we distinguish the role of (...) the CEC from that of the physician, in contrast to some of these authors’ recommendations, which confuse the two roles. (shrink)

Sustained attention, a key cognitive skill that improves during childhood and adolescence, tends to be worse in some emotional and behavioural disorders. Sustained attention is typically studied in non-affective task contexts; here, we used a novel task to index performance in affective versus neutral contexts across adolescence (N = 465; ages 11–18). We asked whether: (i) performance would be worse in negative versus neutral task contexts; (ii) performance would improve with age; (iii) affective interference would be greater in younger adolescents; (...) (iv) adolescents at risk for depression and higher in anxiety would show overall worse performance; and (v) would show differential performance in negative contexts. Results indicated that participants performed more poorly in negative contexts and showed age-related performance improvements. Those at risk of depression performed more poorly than those at lower risk. However, there was no difference between groups as a result of affective context. For anxiety there was no difference in performance as a function of severity. However, those with higher anxiety showed less variance in their reaction times to negative stimuli than those with lower anxiety. One interpretation is that moderate levels of emotional arousal associated with anxiety make individuals less susceptible to the distracting effects of negative stimuli. (shrink)

In this thorough compendium, nineteen accomplished scholars explore, in some manner the values they find inherent in the world, their nature, and revelence through the thought of Frederick Ferré. These essays, informed by the insights of Ferré and coming from manifold perspectives—ethics, philosophy, theology, and environmental studies, advance an ambitious challenge to current intellectual and scholarly fashions.

In this thorough compendium, nineteen accomplished scholars explore, in some manner the values they find inherent in the world, their nature, and revelence through the thought of Frederick FerrZ. These essays, informed by the insights of FerrZ and coming from manifold perspectives—ethics, philosophy, theology, and environmental studies, advance an ambitious challenge to current intellectual and scholarly fashions.

This volume of thirteen essays originated in a conference on Latin philosophy at Columbia University, organized by the editors in 2012. The guiding principle was to examine how writing philosophy in Latin gave a distinctive character to Roman philosophical thinking. The conference was interdisciplinary, involving philosophers and literary scholars, some interested in ancient history as well. In publishing the papers, the editors had in mind as a model Philosophia Togata I and II, the second volume of which is almost twenty (...) years old. More up to date, this volume also aims to fill gaps in the earlier enterprise by devoting one of the four parts to Seneca, not treated as a separate topic there, and by going beyond... (shrink)

Russell’s theory of desire in _The Analysis of_ Mind is subject to a seemingly overwhelming objection, apparently stated first by Wittgenstein and subsequently elaborated even more compellingly by Anthony Kenny. The puzzle is that, before he became a neutral monist, Russell had used essentially the same argument as part of a critique of William James’s theory of knowledge. Since Russell had already formulated the argument as part of his case against generally naturalistic, and specifically neutral monist, theories of propositional (...) attitudes, why did he think his own neutral monist theory of desire was exempt? I canvass various suggestions, but argue that none of them are effective. (shrink)

My study of Mary Shelley and father includes her husband because Percy Shelley’s obsessions with patriarchy, with “ ‘GOD, AND KIND, AND LAW,’ ” influenced profoundly Mary’s* art and life. Percy’s idealizations of father in The Revolt of Islam and Prince Athanase indicated ways or resolving familial antagonisms which Mary adopted and developed her later fiction. Percy’s relationship with Frankenstein is still more intricate. Recognizing that her husband’s obsessions with father and self-creation were contributing to the deterioration of their marriage, (...) Mary represents these obsessions in Victor Frankenstein—partly to vent in art the anger which would have further damaged the marriage, and party to show Percy before it was too late the errors of his ways. It was too late. Percy responded to Frankenstein in Prometheus Unbound and The Cenci with a reaffirmation of sonship which has been largely unrecognized by scholars.Father looms so large for both Mary and Percy Shelley that no one critical approach can account for him fully. At their most idealistic—and thus most traditional—the Shelleys encourage a critical methodology which integrates the traditional disciplines of biographical and close textual analyses. By taking this approach to Mary’s later fiction and to Percy’s The Revolt of Islam, I can not only confirm the prominence of father for the Shelleys but also establish the ideal against which their most subversive and important art was created. Reading this indirect, overdetermined art in light of the negative Oedipus will help answer important questions about Frankenstein, Prometheus Unbound, and The Cenci and will, I hop, add to our understanding of the vexed role of father in the Romantic period and in subsequent generations whose children we are. William Veeder, professor of English at the University of Chicago, has published books on Yeats, Henry James, and Victorian feminism. His Mary Shelley and “Frankenstein”: The Fate of Androgyny will appear in December 1985. The Art of Criticism: Henry James on the Theory and the Practice of Fiction, coedited with Susan M. Griffin, and Dr. Jekyll and Mr. Hyde: The Centenary, a collection of new essays on Stevenson’s novel, are also forthcoming . He is currently at work on The Serpent’s Tale: Anglo-American Gothic Fiction, 1885-1914. (shrink)

v. 1. Medieval and early classical science.--v. 2. Classical and contemporary science.

Brief thumbnail sketches capture group interest and show the relevance of ethical considerations in real life situations. Bill Bain has considerable experience of business and is currently a PhD student at the Management School of London University's Imperial College, 53 Prince's Gate, Exhibition Road, London SW7 2PG.

Contemporary thinkers who address the problem of causal relations generally favor Hume’s analysis, although some periodically manifest interest in Aristotle’s exposition as an important and viable alternative. Few, however, find among the many philosophers who came between Aristotle and Hume any worthwhile contributor to the development of this problematic. Some might note, for example, Nicholas of Autrecourt as a medieval precursor of Hume, but this merely keeps the discussion fluctuating between the same two poles. This essay aims to call attention (...) to a different and intermediate view, not hitherto noted, that was proposed in the High Middle Ages by Thomas Aquinas. It argues that Aquinas made a significant advance beyond Aristotle in his analysis of antecedent causation, and thereby made possible the certification of some elements in Hume’s analysis, without subscribing to its more extreme results. In so doing, moreover, Aquinas adumbrated some problems in contemporary analytic discussions of the causal relationships between events, and consequently may shed light on their solution. (shrink)

This book is the first detailed reconstruction of the late work of John Rawls, who was perhaps the most influential philosopher of the twentieth century. Rawls's 1971 treatise, A Theory of Justice, stimulated an outpouring of commentary on 'justice-as-fairness,' his conception of justice for an ideal, self-contained, modern political society. Most of that commentary took Rawls to be defending welfare-state capitalism as found in Western Europe and the United States. Far less attention has been given to Rawls's 2001 book, Justice (...) as Fairness: A Restatement. In the Restatement, Rawls not only substantially reformulates the 'original position' argument for the two principles of justice-as-fairness but also repudiates capitalist regimes as possible embodiments. Edmundson further develops Rawls's non-ideal theory, which guides us when we find ourselves in a society that falls well short of justice. (shrink)

The use of mathematical models to support decision making is proliferating in both the public and private sectors. Advances in computer technology and greater opportunities to learn the appropriate techniques are extending modeling capabilities to more and more people. As powerful decision aids, models can be both beneficial or harmful. At present, few safeguards exist to prevent model builders or users from deliberately, carelessly, or recklessly manipulating data to further their own ends. Perhaps more importantly, few people understand or appreciate (...) that harm can be caused when builders or users fail to recognize the values and assumptions on which a model is based or fail to take into account all the groups who would be affected by a model's results. This volume provides a setting for a dialogue about ethics and shows the need to continue and define a vocabulary for exploring ethical concerns. It will become increasingly important for model builders and users to have a clear and strong code of ethics to guide them in making the ethical decisions they surely will have to face. (shrink)

A summary of basics for student and seminarian.

The problem of Galileo's logical methodology has long interested scholars. In this volume William A. Wallace offers a solution that is completely unexpected, yet backed by convincing documentary evidence. His analysis starts with an early notebook Galileo wrote at Pisa, appropriating a Jesuit professor's exposition of the Posterior Analystics of Aristotle, and ends with one of the last letters Galileo wrote, stating that in logic he has been a Peripatetic all his life. Wallace's detective work unearths the complete logic (...) course from which the notebook was excerpted, then proceeds to show how its terminology and methodology continue to surface in Galileo's later writings in which he founds his new sciences of the heavens and of local motion. The result is a tour de force that commends itself not only to Galileo's scholars and to logicians, philosophers, and historians, but to anyone interested in the epistemic roots of modern science. (shrink)

Philosophy, despite its typical attitude of detachment and abstraction, has for most of its long history been engaged with the practical and mundane-seeming question of whether there is a duty to obey the law. As Matthew Kramer has recently summarized: “For centuries, political and legal theorists have pondered whether each person is under a general obligation of obedience to the legal norms of the society wherein he or she lives. The obligation at issue in those theorists' discussions is usually taken (...) to be prima-facie, comprehensively applicable, universally borne, and content-independent.” This essay is a commentary on the current state of discussion of this perennial philosophical topic. (shrink)

Rights come in various types - human, moral, civil, political and legal - and claims about who has a right, and to what, are often contested. What are rights? Are they timeless and universal, or merely conventional? How are they related to other morally significant values, such as well-being, autonomy, and community? Can animals have rights? Or fetuses? Do we have a right to do as we please so long as we do not harm others? This is the only accessible (...) and readable introduction to the history, logic, moral implications, and political tendencies of the idea of rights. It is organized chronologically and discusses important events, such as the French Revolution. As an undergraduate text it is well-suited to introductions to political philosophy, moral philosophy, and ethics. It could also be used in courses on political theory in departments of political science and government, and in courses on legal theory in law schools. (shrink)

Darwin's greatest accomplishment was to show how life might be explained as the result of natural selection. But does Darwin's theory mean that life was unintended? William A. Dembski argues that it does not. In this book Dembski extends his theory of intelligent design. Building on his earlier work in The Design Inference (Cambridge, 1998), he defends that life must be the product of intelligent design. Critics of Dembski's work have argued that evolutionary algorithms show that life can be (...) explained apart from intelligence. But by employing powerful recent results from the No Free Lunch Theory, Dembski addresses and decisively refutes such claims. As the leading proponent of intelligent design, Dembski reveals a designer capable of originating the complexity and specificity found throughout the cosmos. Scientists and theologians alike will find this book of interest as it brings the question of creation firmly into the realm of scientific debate. (shrink)

The design inference uncovers intelligent causes by isolating their key trademark: specified events of small probability. Just about anything that happens is highly improbable, but when a highly improbable event is also specified undirected natural causes lose their explanatory power. Design inferences can be found in a range of scientific pursuits from forensic science to research into the origins of life to the search for extraterrestrial intelligence. This challenging and provocative 1998 book shows how incomplete undirected causes are for science (...) and breathes new life into classical design arguments. It will be read with particular interest by philosophers of science and religion, other philosophers concerned with epistemology and logic, probability and complexity theorists, and statisticians. (shrink)

The aim of this paper is to report some little-known aspects of sixteenth-century physics as these relate to the development of mechanics in the seventeenth century. The research herein reported grew out of a study on the mechanics of Domingo de Soto, a sixteenth-century Spanish scholastic,1 which has been concerned, in part, with examining critically Pierre Duhem's thesis that the English “Calculatores” of the fourteenth century were a primary source for Galileo's science.2 The conclusion to which this has come, thus (...) far, is that Duhem had important insights into the late medieval preparation for the modern science of mechanics, but that he left out many of the steps. And the steps are important, whether one holds for a continuity theory or a discontinuity theory vis-à-vis the connection between late medieval and early modern science. (shrink)

THE pervasive role of causality in the development of Galileo's science has been obscured largely by two factors. Philosophers who address the problem usually exhibit an anti-causal bias traceable to David Hume, and this disposes them to concentrate on passages in Galileo's writings that can be given a positivist interpretation. Historians are likewise selective in their treatment of his texts, for they tend to enforce sharp dichotomies between Galileo's earlier Latin compositions and his treatises in Italian, especially the two dialogues (...) of his later years for which he is justly famous. With this twofold reinforcement from philosophers and historians of science, one might think that the problem of causality in Galileo's science is whether or not the Italian physicist actually reasoned in causal terms such as those explained in Aristotle's Posterior Analytics. A large and influential school at the moment would say that this is the question, and that it is best answered in the negative: causal analysis played little or no role in the development of Galileo's science, and certainly less and less in his later years. Indeed, it was his rejection of Aristotle precisely on these grounds that merits for him the title, "Father of Modern Science," the canons of which science are almost diametrically opposite those of the science advocated by Greek peripatetics and medieval scholastics, before the onset of the modern era. (shrink)

How is a legitimate state possible? Obedience, coercion and intrusion are three ideas that seem inseparable from all government and seem to render state authority presumptively illegitimate. This book exposes three fallacies inspired by these ideas and in doing so challenges assumptions shared by liberals, libertarians, cultural conservatives, moderates and Marxists. In three clear and tightly argued essays William Edmundson dispels these fallacies and shows that living in a just state remains a worthy ideal. This is an important book (...) for all philosophers, political scientists and legal theorists as well as other readers interested in the views of Rawls, Dworkin and Nozick, many of whose central ideas are subjected to rigorous critique. (shrink)

William Galston is a distinguished political philosopher whose work is informed by the experience of having also served from 1993–5 as President Clinton's Deputy Assistant for Domestic Policy. He is thus able to speak with an authority unique amongst political theorists about the implications of advancing certain moral and political values in practice. The foundational argument of this 2002 book is that liberalism is compatible with the value pluralism first espoused by Isaiah Berlin. William Galston defends a version (...) of value pluralism - liberal pluralism - and argues, against the contentions of John Gray and others, that it undergirds a kind of liberal politics that gives weight to the ability of individuals and groups to live their lives in accordance with their deepest beliefs about what gives meaning and purpose to life. (shrink)