Results for 'stop codon'

993 found
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  1.  8
    Average and Standard Deviation of the Error Function for Random Genetic Codes with Standard Stop Codons.Dino G. Salinas - 2021 - Acta Biotheoretica 70 (1):1-16.
    The origin of the genetic code has been attributed in part to an accidental assignment of codons to amino acids. Although several lines of evidence indicate the subsequent expansion and improvement of the genetic code, the hypothesis of Francis Crick concerning a frozen accident occurring at the early stage of genetic code evolution is still widely accepted. Considering Crick’s hypothesis, mathematical descriptions of hypothetical scenarios involving a huge number of possible coexisting random genetic codes could be very important to explain (...)
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  2.  19
    Non‐stop decay—a new mRNA surveillance pathway.Shobha Vasudevan, Stuart W. Peltz & Carol J. Wilusz - 2002 - Bioessays 24 (9):785-788.
    Gene expression is an inherently complex process and errors often occur during the transcription and processing of mRNAs. Several surveillance mechanisms have evolved to check the fidelity at each step of mRNA manufacture. Two recent reports describe the identification of a novel pathway in eukaryotes that recognizes and degrades mRNAs that lack a stop codon.1,2 The non‐stop decay mechanism releases ribosomes stalled at the 3′ end of a mRNA and stimulates the exosome to rapidly degrade the transcript. (...)
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  3.  10
    Negative CG dinucleotide bias: An explanation based on feedback loops between Arginine codon assignments and theoretical minimal RNA rings.Jacques Demongeot, Andrés Moreira & Hervé Seligmann - 2021 - Bioessays 43 (3):2000071.
    Theoretical minimal RNA rings are candidate primordial genes evolved for non‐redundant coding of the genetic code's 22 coding signals (one codon per biogenic amino acid, a start and a stop codon) over the shortest possible length: 29520 22‐nucleotide‐long RNA rings solve this min‐max constraint. Numerous RNA ring properties are reminiscent of natural genes. Here we present analyses showing that all RNA rings lack dinucleotide CG (a mutable, chemically instable dinucleotide coding for Arginine), bearing a resemblance to known (...)
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  4.  14
    Why Is AUG the Start Codon?Jacques Demongeot & Hervé Seligmann - 2020 - Bioessays 42 (6):1900201.
    The rational design of theoretical minimal RNA rings predetermines AUG as the universal start codon. This design maximizes coded amino acid diversity over minimal sequence length, defining in silico theoretical minimal RNA rings, candidate ancestral genes. RNA rings code for 21 amino acids and a stop codon after three consecutive translation rounds, and form a degradation‐delaying stem‐loop hairpin. Twenty‐five RNA rings match these constraints, ten start with the universal initiation codon AUG. No first codon bias (...)
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  5.  1
    mRNA context and translation factors determine decoding in alternative nuclear genetic codes.Ali Salman, Nikita Biziaev, Ekaterina Shuvalova & Elena Alkalaeva - forthcoming - Bioessays.
    The genetic code is a set of instructions that determine how the information in our genetic material is translated into amino acids. In general, it is universal for all organisms, from viruses and bacteria to humans. However, in the last few decades, exceptions to this rule have been identified both in pro‐ and eukaryotes. In this review, we discuss the 16 described alternative eukaryotic nuclear genetic codes and observe theories of their appearance in evolution. We consider possible molecular mechanisms that (...)
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  6.  24
    The Uroboros Theory of Life’s Origin: 22-Nucleotide Theoretical Minimal RNA Rings Reflect Evolution of Genetic Code and tRNA-rRNA Translation Machineries.Jacques Demongeot & Hervé Seligmann - 2019 - Acta Biotheoretica 67 (4):273-297.
    Theoretical minimal RNA rings attempt to mimick life’s primitive RNAs. At most 25 22-nucleotide-long RNA rings code once for each biotic amino acid, a start and a stop codon and form a stem-loop hairpin, resembling consensus tRNAs. We calculated, for each RNA ring’s 22 potential splicing positions, similarities of predicted secondary structures with tRNA vs. rRNA secondary structures. Assuming rRNAs partly derived from tRNA accretions, we predict positive associations between relative secondary structure similarities with rRNAs over tRNAs and (...)
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  7.  26
    Dinoflagellate mitochondrial genomes: stretching the rules of molecular biology.Ross F. Waller & Christopher J. Jackson - 2009 - Bioessays 31 (2):237-245.
    Mitochondrial genomes represent relict bacterial genomes derived from a progenitor α‐proteobacterium that gave rise to all mitochondria through an ancient endosymbiosis. Evolution has massively reduced these genomes, yet despite relative simplicity their organization and expression has developed considerable novelty throughout eukaryotic evolution. Few organisms have reengineered their mitochondrial genomes as thoroughly as the protist lineage of dinoflagellates. Recent work reveals dinoflagellate mitochondrial genomes as likely the most gene‐impoverished of any free‐living eukaryote, encoding only two to three proteins. The organization and (...)
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  8.  5
    Genetics and molecular biology of rhythms.Jeffrey C. Hall & Michael Rosbash - 1987 - Bioessays 7 (3):108-112.
    Mutations that disrupt biological rhythms have existed in microbial and metazoan eukaryotes for some time. They have recently begun to be studied with increasing intensity, both in terms of phenotypic effects of the relevant genetic variants, and with regard to molecular isolation and analysis of the genes defined by two of the ‘clock mutations’. These genetic loci, called period (per) in Drosophila and frequency (frq) in Neurospora, influence not only the basic characteristics of circadian rhythmicity, but also temperature compensation of (...)
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  9.  26
    A gene for speed? The evolution and function of α‐actinin‐3.Daniel G. MacArthur & Kathryn N. North - 2004 - Bioessays 26 (7):786-795.
    The α‐actinins are an ancient family of actin‐binding proteins that play structural and regulatory roles in cytoskeletal organisation and muscle contraction. α‐actinin‐3 is the most‐highly specialised of the four mammalian α‐actinins, with its expression restricted largely to fast glycolytic fibres in skeletal muscle. Intriguingly, a significant proportion (∼18%) of the human population is totally deficient in α‐actinin‐3 due to homozygosity for a premature stop codon polymorphism (R577X) in the ACTN3 gene. Recent work in our laboratory has revealed a (...)
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  10.  4
    Rebirth of the translational machinery: The importance of recycling ribosomes.David J. Young & Nicholas R. Guydosh - 2022 - Bioessays 44 (4):2100269.
    Translation of the genetic code occurs in a cycle where ribosomes engage mRNAs, synthesize protein, and then disengage in order to repeat the process again. The final part of this process—ribosome recycling, where ribosomes dissociate from mRNAs—involves a complex molecular choreography of specific protein factors to remove the large and small subunits of the ribosome in a coordinated fashion. Errors in this process can lead to the accumulation of ribosomes at stop codons or translation of downstream open reading frames (...)
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  11.  20
    Leer a los clásicos en el Renacimiento bizantino Reading the Classics in the Byzantine Renaissance.Juan Signes Codoñer & Klaus Alpers - 2012 - Minerva: Revista de Filología Clásica 25:251-256.
  12.  15
    Los eslavos en las fuentes bizantinas de los siglos IX/X: el De administrado imperio de Constantino VII Porfirogéneto.Juan Signes Codoñer - 2004 - 'Ilu. Revista de Ciencias de Las Religiones 9:115-132.
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  13.  13
    La physique de Sénèque: Ordonnance et structure des ‘Naturales Quaestiones’.Carmen Codoñer - 1987 - In Wolfgang Haase (ed.), Philosophie, Wissenschaften, Technik. Philosophie. De Gruyter. pp. 1779-1822.
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  14. Byzantines or arabs? Melkite christianity in the lands of Islam before the crusades.Juan Signes-Codoner - 2012 - Al-Qantara 33 (2):405 - 412.
     
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  15.  26
    Los eslavos en las fuentes bizantinas en los siglos IX-X: el De administrando imperio de Constantino VII Porfirogéneto.Signes Codoñer Juan - forthcoming - 'Ilu. Revista de Ciencias de Las Religiones.
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  16.  12
    II. Abteilung.Beat Brenk, Athanasios Markopoulos, Kostis Smyrlis, Zachary Chitwood, Tomás Fernández, Ioannis Polemis, Raphael Brendel, Rudolf Stefec & Juan Signes Codoñer - 2018 - Byzantinische Zeitschrift 111 (1):157-212.
    Name der Zeitschrift: Byzantinische Zeitschrift Jahrgang: 111 Heft: 1 Seiten: 157-212.
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  17.  22
    An annotated bibliography of Byzantine studies.P. Schreiner, C. SCholz, Kristoffel Demoen, A. Berger, F. TinneFeld, C. Jolivet-Levy, P. Odorico, A. KArpozilos, T. Kolias, J. Albani, A. AcconciA Longo, H. Wada, W. Aerts, E. KislingEr, Jn Ljubarskij, J. Rosenqvist, J. Signes Codoner, A. YAsinovskyi, T. Olajos, W. Kaegi, J. Diethart, W. Seibt & S. TroianoS - 2000 - Byzantinische Zeitschrift 93 (2):663-795.
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  18.  30
    An annotated bibliography of Byzantine studies.P. Schreiner, C. SCholz, P. Grossmann, Kristoffel Demoen, V. GjuzeleV, A. Berger, W. Brandes, F. TinneFeld, E. JEffreys, C. Jolivet-Levy, T. Kolias, J. Albani, S. Kalopissi-Verti, A. AcconciA Longo, E. KislingEr, W. Aerts, M. Grunbart, J. Koder, M. Hinterberger, Sv Bliznjuk, Jn Ljubarskij, M. SalaMon, J. Rosenqvist, J. Signes Codoner, A. YAsinovskyi, A. Cutler, W. Kaegi, Am Talbot, J. Diethart, E. Trapp, E. GamillschEg, B. Mondrain, A. BeihAmmer, A. Lohbeck, W. Seibt, F. Goria & S. TroianoS - 2001 - Byzantinische Zeitschrift 94 (1):375-539.
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  19.  56
    Annotated bibliography of Byzantine studies.P. Schreiner, C. SCholz, S. Gunter, A. MoffAtt, Kristoffel Demoen, M. Altripp, A. Berger, F. TinneFeld, C. Jolivet-Levy, P. Odorico, J. Albani, S. Kalopissi-Verti, A. AcconciA Longo, E. KislingEr, W. Aerts, M. Grunbart, J. Koder, E. PopEscu, J. Rosenqvist, J. Signes Codoner, A. Cutler, W. Kaegi, Am Talbot, L. Maksimovic, E. Trapp, E. GamillschEg, B. Mondrain, A. BeihAmmer, Av Stockhausen, A. Lohbeck, C. Morrisson, W. Seibt, S. TroianoS, T. Kolias & M. Featherstone - 2001 - Byzantinische Zeitschrift 94 (2):766-905.
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  20.  48
    A bibliography of Byzantine studies.P. Schreiner, S. Guntner, P. Grossmann, Kristoffel Demoen, M. Altripp, A. Berger, A. BrAndes, F. TinneFeld, Mm Mango, J. Albani, S. Kalopissi-Verti, A. AcconciA Longo, E. KislingEr, W. Aerts, M. Grunbart, J. Koder, M. SalaMon, Sv Bliznjuk, J. Rosenqvist, J. Signes Codoner, A. Cutler, W. Kaegi, Am Talbot, L. Maksimovic, D. Triantaphyllopoulos, B. Palme, E. Trapp, E. GamillschEg, B. Mondrain, E. VElkovska, Av Stockhausen, W. Seibt, S. TroianoS, T. Kolias, M. Featherstone & I. Herbert - 2003 - Byzantinische Zeitschrift 95 (1):184-397.
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  21. Is armed humanitarian.Intervention to Stop Mass Killing, Morally Obligatory & I. Moral Deliberation - 2001 - Public Affairs Quarterly 15 (3):173.
  22.  35
    Giorgio Agamben, The Signature of all Things: On Method, trans. Luca Di Santo and Kevin Attell (Cambridge: MIT Press, 2009). Sharon Anderson-Gold and Pablo Muchnik, eds., Kant's Anatomy of Evil (Cambridge: Cambridge University Press, 2010). John Arthos, The Inner Word in Gadamer's Hermeneutics (Notre Dame). [REVIEW]Jean-Paul Sartre & Stop Making Excuses - 2010 - Graduate Faculty Philosophy Journal 31 (1).
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  23. title: N 345. anicce pawae ruppe bhuyagassa taha maha-samudde ya ee khalu ahigara ajjhayanammi vimuttie a: a sloka pdda. Impermanence, a mountain, silver, a snake and the ocean—these one.Consider This Supreme, A. Wise Man, Should Give, Once Stop Killing & Acquiring Possessions - 1990 - Journal of Indian Philosophy 18:29.
     
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  24. Stop Talking about Fake News!Joshua Habgood-Coote - 2019 - Inquiry: An Interdisciplinary Journal of Philosophy 62 (9-10):1033-1065.
    Since 2016, there has been an explosion of academic work and journalism that fixes its subject matter using the terms ‘fake news’ and ‘post-truth’. In this paper, I argue that this terminology is not up to scratch, and that academics and journalists ought to completely stop using the terms ‘fake news’ and ‘post-truth’. I set out three arguments for abandonment. First, that ‘fake news’ and ‘post-truth’ do not have stable public meanings, entailing that they are either nonsense, context-sensitive, or (...)
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  25.  25
    Quadruplet codons: One small step for a ribosome, one giant leap for proteins.Irene A. Chen & Michael Schindlinger - 2010 - Bioessays 32 (8):650-654.
  26.  96
    Early stopping of RCTs: two potential issues for error statistics.Roger Stanev - 2015 - Synthese 192 (4):1089-1116.
    Error statistics is an important methodological view in philosophy of statistics and philosophy of science that can be applied to scientific experiments such as clinical trials. In this paper, I raise two potential issues for ES when it comes to guiding, and explaining early stopping of randomized controlled trials : ES provides limited guidance in cases of early unfavorable trends due to the possibility of trend reversal; ES is silent on how to prospectively control error rates in experiments requiring multiple (...)
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  27.  75
    Stopping rules and data monitoring in clinical trials.Roger Stanev - 2012 - In H. W. De Regt (ed.), EPSA Philosophy of Science: Amsterdam 2009, The European Philosophy of Science Association Proceedings Vol. 1, 375-386. Springer. pp. 375--386.
    Stopping rules — rules dictating when to stop accumulating data and start analyzing it for the purposes of inferring from the experiment — divide Bayesians, Likelihoodists and classical statistical approaches to inference. Although the relationship between Bayesian philosophy of science and stopping rules can be complex (cf. Steel 2003), in general, Bayesians regard stopping rules as irrelevant to what inference should be drawn from the data. This position clashes with classical statistical accounts. For orthodox statistics, stopping rules do matter (...)
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  28.  15
    Voluntarily Stopping Eating and Drinking: A Normative Comparison with Refusing Lifesaving Treatment and Advance Directives.Paul T. Menzel - 2017 - Journal of Law, Medicine and Ethics 45 (4):634-646.
    Refusal of lifesaving treatment, and such refusal by advance directive, are widely recognized as ethically and legally permissible. Voluntarily stopping eating and drinking is not. Ethically and legally, how does VSED compare with these two more established ways for patients to control the end of life? Is it more questionable because with VSED the patient intends to cause her death, or because those who assist it with palliative care could be assisting a suicide?In fact the ethical and legal basis for (...)
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  29. Stopping points: ‘I’, immunity and the real guarantee.Annalisa Coliva - 2017 - Inquiry: An Interdisciplinary Journal of Philosophy 60 (3):233-252.
    The aim of the paper is to bring out exactly what makes first-personal contents special, by showing that they perform a distinctive cognitive function. Namely, they are stopping points of inquiry. First, I articulate this idea and then I use it to clear the ground from a troublesome conflation. That is, the conflation of this particular function all first-person thoughts have with the property of immunity to error through misidentification, which only some I-thoughts enjoy. Afterward, I show the implications of (...)
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  30.  19
    The Stopping Rule Principle and Confirmational Reliability.Samuel C. Fletcher - 2023 - Journal for General Philosophy of Science / Zeitschrift für Allgemeine Wissenschaftstheorie 55 (1):1-28.
    The stopping rule for a sequential experiment is the rule or procedure for determining when that experiment should end. Accordingly, the stopping rule principle (SRP) states that the evidential relationship between the final data from a sequential experiment and a hypothesis under consideration does not depend on the stopping rule: the same data should yield the same evidence, regardless of which stopping rule was used. I clarify and provide a novel defense of two interpretations of the main argument against the (...)
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  31.  27
    Stopping anger and anxiety: Evidence that inhibitory ability predicts negative emotional responding.David Tang & Brandon J. Schmeichel - 2014 - Cognition and Emotion 28 (1):132-142.
    Research has begun to suggest that cognitive ability contributes to emotional processes and responses. The present study sought novel evidence for this hypothesis by examining the relationship between individual differences in the capacity for inhibitory control and responses to a common emotion-induction procedure involving autobiographical memories. Participants first completed a stop-signal task to measure inhibitory control and then underwent an anger, anxiety, or neutral emotion induction. Performance on the stop-signal task predicted emotional responses such that participants with poorer (...)
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  32. Stop Making Sense? On a Puzzle about Rationality.Littlejohn Clayton - 2018 - Philosophy and Phenomenological Research:257-272.
    In this paper, I present a puzzle about epistemic rationality. It seems plausible that it should be rational to believe a proposition if you have sufficient evidential support for it. It seems plausible that it rationality requires you to conform to the categorical requirements of rationality. It also seems plausible that our first-order attitudes ought to mesh with our higher-order attitudes. It seems unfortunate that we cannot accept all three claims about rationality. I will present three ways of trying to (...)
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  33.  37
    Stopping rules as experimental design.Samuel C. Fletcher - 2019 - European Journal for Philosophy of Science 9 (2):1-20.
    A “stopping rule” in a sequential experiment is a rule or procedure for deciding when that experiment should end. Accordingly, the “stopping rule principle” states that, in a sequential experiment, the evidential relationship between the final data and an hypothesis under consideration does not depend on the experiment’s stopping rule: the same data should yield the same evidence, regardless of which stopping rule was used. In this essay, I reconstruct and rebut five independent arguments for the SRP. Reminding oneself that (...)
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  34.  52
    Stop Telling me What to Feel!Hanna Pickard - 2019 - Philosophical Topics 47 (2):1-25.
    “Don’t be jealous of your sister.” “Don’t be angry with your father.” “You should be more forgiving.” “You ought to feel terrible for what you’ve done.” “You ought to feel ashamed of yourself!” It is common practice within our society to morally reprimand people for their emotions, thereby expressing a kind of moralism: the idea that there are morally right and morally wrong ways to feel. Drawing on an alternative way of engaging with emotions derived from my experience working clinically (...)
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  35.  6
    Stop being reasonable.Eleanor Gordon-Smith - 2019 - Sydney, NSW: NewSouth Publishing.
    What if you're not who you think you are? What if you don't really know the people closest to you? And what if your most deeply-held beliefs turn out to be. wrong? In Stop Being Reasonable, philosopher Eleanor Gordon-Smith tells gripping true stories that show the limits of human reason. Susie realises her husband harbours a terrible secret, Dylan leaves the cult he's been raised in since birth, Alex discovers he can no longer return to his former identity after (...)
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  36.  28
    Stop-Motion Animation’s Object Substitutions and Non-Depictive Representation.Andrea Marie Comiskey - 2024 - Film and Philosophy 28:111-129.
    This article explores a distinctive representational strategy used in stop-motion animation: the object substitution. Using as its central example a children’s TV episode in which brushes stand in for dogs, it explains how this strategy produces a complex relationship between depiction and representation. The analysis highlights the pragmatic underpinnings of various theories of pictorial and cinematic representation, arguing that, in a substitution, depicted elements constitute explicatures and represented ones implicatures. Connecting this strategy to humans’ capacity for pareidolia (seeing things (...)
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  37.  15
    Retrieval stopping can reduce distress from aversive memories.Satoru Nishiyama & Satoru Saito - 2022 - Cognition and Emotion 36 (5):957-974.
    Aversive memories have the potential to impair one’s psychological well-being. It is desirable to reduce the anguish over such memories, as well as the chance that they will be retrieved. In two experiments, we investigated whether retrieval stopping reduces the distress elicited by negative memories retrieved from cues and how the effects of retrieval stopping are modulated by mental disorders, such as depression and anxiety. Participants engaged in retrieval stopping of aversive scene memories without any diversionary thoughts (direct suppression, Experiment (...)
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  38.  49
    Stopping to Reflect.M. J. Schervish, T. Seidenfeld & J. B. Kadane - 2004 - Journal of Philosophy 101 (6):315-322.
  39.  6
    Stopping to Reflect.Mj Schervish, T. Seidenfeld & Jb Kadane - 2004 - Journal of Philosophy 101 (6):315-322.
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  40.  8
    Stopping Criminalization at the Bedside.Wendy A. Bach & Mishka Terplan - 2023 - Journal of Law, Medicine and Ethics 51 (3):533-537.
    Low-income women and, disproportionately low-income women of color seeking reproductive and pregnancy care are increasingly subject to what this article terms carceral care – care compromised by its’ proximity to punishment systems. This article identifies the legal and health care practice mechanisms leading to carceral care and proposes solutions designed to stop criminalization at the bedside.
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  41.  21
    Stop crying! The impact of situational demands on interpersonal emotion regulation.Lisanne S. Pauw, Disa A. Sauter, Gerben A. van Kleef & Agneta H. Fischer - 2019 - Cognition and Emotion 33 (8):1587-1598.
    Crying is a common response to emotional distress that elicits support from the environment. People may regulate another’s crying in several ways, such as by providing socio-affective support (e.g. comforting) or cognitive support (e.g. reappraisal), or by trying to emotionally disengage the other by suppression or distraction. We examined whether people adapt their interpersonal emotion regulation strategies to the situational context, by manipulating the regulatory demand of the situation in which someone is crying. Participants watched a video of a crying (...)
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  42.  18
    The Stop.David Appelbaum - 1995 - State University of New York Press.
    This book is about the turn toward consciousness by which we pass from ignorance to knowledge. The stop is the spark of initiation that arouses our habitual inattentiveness, motivating us toward a higherunderstanding.
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  43.  6
    The Stop.David Appelbaum - 1995 - Albany: SUNY Press.
    This book is about the turn toward consciousness by which we pass from ignorance to knowledge. The stop is the spark of initiation that arouses our habitual inattentiveness, motivating us toward a higherunderstanding.
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  44.  11
    Stop and Smell the Roses.Safiye Yiğit - 2016 - Croatian Journal of Philosophy 16 (3):341-360.
    Ilhan Inan’s book The Philosophy of Curiosity is an exploration of understanding human curiosity and its relation to the use of language. He introduces the notion of inostensible reference (or reference to the unknown) that renders an interesting question possible. He claims that our aptitude for this kind of reference is what enables us to become aware of our ignorance and be curious. For him, there are two ways in which a proposition could be inostensible to a subject: one possibility (...)
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  45.  25
    Stop making sense of Bell’s theorem and nonlocality?Federico Laudisa - 2018 - European Journal for Philosophy of Science 8 (2):293-306.
    In a recent paper on Foundations of Physics, Stephen Boughn reinforces a view that is more shared in the area of the foundations of quantum mechanics than it would deserve, a view according to which quantum mechanics does not require nonlocality of any kind and the common interpretation of Bell theorem as a nonlocality result is based on a misunderstanding. In the present paper I argue that this view is based on an incorrect reading of the presuppositions of the EPR (...)
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  46.  38
    Stop and frisk : sex, torture, control.Paul Butler - 2011 - In Austin Sarat, Lawrence Douglas & Martha Merrill Umphrey (eds.), Law as punishment/law as regulation. Stanford, California: Stanford Law Books.
    This chapter explores the expressive meaning of stops and frisks, paying special attention to frisks—police touching of people who, in the eyes of the “law,” are innocent. It argues that stops and frisks can be constructed as a form of torture, the effect of which is the assertion of police dominance of the streets. Stops and frisks cause injuries similar to those of illegal forms of tortures, and have the same kinds of “benefits.” Stops and frisks blur the line between (...)
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  47. When do we stop digging? Conditions on a fundamental theory of physics.Karen Crowther - 2019 - In Anthony Aguirre, Brendan Foster & Zeeya Merali (eds.), What is Fundamental? Cham: Springer Verlag. pp. 123-133.
    In seeking an answer to the question of what it means for a theory to be fundamental, it is enlightening to ask why the current best theories of physics are not generally believed to be fundamental. This reveals a set of conditions that a theory of physics must satisfy in order to be considered fundamental. Physics aspires to describe ever deeper levels of reality, which may be without end. Ultimately, at any stage we may not be able to tell whether (...)
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  48.  55
    The Stopping Power of Sources: Implied Causal Mechanisms and Historical Interpretations in (Mearsheimer’s) Arguments on the Russo-Ukrainian War.Jonas J. Driedger - 2023 - Analyse & Kritik 45 (1):137-155.
    The article analyzes arguments, made by John J. Mearsheimer and others, that the Russian invasion of Ukraine in 2022 was largely caused by Western policy. It finds that these arguments rely on a partially false and incomplete reading of history. To do so, the article identifies a range of premises that are both foundational to Mearsheimer’s claims and based on implied or explicit historical interpretations. This includes the varying policies of Ukraine toward NATO and the EU as well as the (...)
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  49.  8
    Voluntarily Stopping Eating and Drinking: Conceptual, Personal, and Policy Questions.John C. Moskop - 2021 - Journal of Medicine and Philosophy 46 (6):805-826.
    Although voluntarily stopping eating and drinking as a way to hasten one’s death is not yet a widely recognized practice in the United States, it has received increasing attention in the medical and bioethics literature in recent years. After a brief review of the broader context of human death and dying, this article poses and examines 11 conceptual, personal, and public policy questions about VSED. The article identifies essential features of VSED and discusses whether VSED is a type of suicide. (...)
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  50. Stop re-inventing the wheel: or how ELSA and RRI can align.Mark Ryan & Vincent Blok - 2023 - Journal of Responsible Innovation (x):x.
    Ethical, Legal and Social Aspects (ELSA) originated in the 4thEuropean Research Framework Programme (1994) andresponsible research and innovation (RRI) from the EC researchagenda in 2010. ELSA has received renewed attention inEuropean funding schemes and research. This raises the questionof how these two approaches to social responsibility relate toone another and if there is the possibility to align. There is aneed to evaluate the relationship/overlap between ELSA and RRIbecause there is a possibility that new ELSA research will reinventthe wheel if it (...)
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