By combining and augmenting recent arguments that have appeared in the literature, I show how a modified Rawlsian theory of justice generates a strong environmental and animal rights ethic. These modifications include significant changes in the conditions of the contract situation vis-a-vis A Theory of Justice, but I argue that these modifications are in fact more consistent with Rawls’ basic assumptions about the functions of a veil of ignorance and a thin theory of the good.

In this paper I present the basic outlines of a nonstandard interpretation of Sein und Zeit. The merit of this interpretation is that it brings out and develops some of the radical possibilities contained in this rich text, possibilities which, I believe, have yet to be given their due. On the basis of this interpretation it is clear not only how Heidegger’s ontology departs from its Cartesian and Kantian predecessors, but also how his ontology puts the traditional mind/body problem, and (...) the problem of the external world, onto radically new grounds. However, unlike standard interpretations of Sein und Zeit, I argue that these new grounds neither resolve, nor dissolve, these problems, and that Heidegger’s discussion of the so-called “scandal of philosophy” is misleading at best. (shrink)

In this paper I present the basic outlines of a nonstandard interpretation of Sein und Zeit. The merit of this interpretation is that it brings out and develops some of the radical possibilities contained in this rich text, possibilities which, I believe, have yet to be given their due. On the basis of this interpretation it is clear not only how Heidegger’s ontology departs from its Cartesian and Kantian predecessors, but also how his ontology puts the traditional mind/body problem, and (...) the problem of the external world, onto radically new grounds. However, unlike standard interpretations of Sein und Zeit, I argue that these new grounds neither resolve, nor dissolve, these problems, and that Heidegger’s discussion of the so-called “scandal of philosophy” is misleading at best. (shrink)

Peoples’ perceptions of healthy eating are influenced by the cultural context in which they occur. Despite this general acceptance by health practitioners and social scientists, studies suggest that there remains a relative homogeneity around peoples’ perceptions that informs a hegemonic discourse around healthy eating. People often describe healthy eating in terms of learned information from sources that reflect societies’ norms and values, such as the Canada Food Guide and the ubiquitous phrase “fruits and vegetables”. Past research has examined how built (...) environments shape people’s access to healthy living options, such as distribution of grocers versus convenience stores and fast food restaurants. Often overlooked is an in-depth understanding of how social contexts interact with built environments, molding peoples’ perceptions of healthy eating. This paper reports on perceptions of healthy eating in four communities across Alberta, Canada. A photovoice methodology was employed to elicit perceptions of healthy eating with 35 participants. This study illustrates how participants’ photographs and their stories convey multiple meanings about healthy eating within their own lives and communities. Findings suggest that a ‘local’ context is an important part of the discourse centered around the promotion of healthy eating practices in these and potential other communities. (shrink)

Wilhelm Bousset, a leading member of the religionsgeschichtliche school and author of a seminal work on early Christology, Kyrios Christos, is typically regarded by reviewers of his work as a classic nineteenth-century liberal who sought a secure foundation for faith in the historical Jesus. However, this view of Bousset fails to appreciate the significant development of his theological perspective on the relationship between faith and history, a perspective that underwent a profound shift due to the influence of the English historian (...) Thomas Carlyle and the Kantian philosopher Jakob Friedrich Fries. It is the influence of these two figures that enables Bousset to justify a full-scale flight from history and to seek faith's foundation elsewhere, in the poetic symbol of Jesus Christ. The resulting solution to the problem of faith and history represents a unique and compelling alternative to the solutions of the leading theologians and New Testament scholars of the early twentieth century. (shrink)

Doubly robust (DR) estimators are an important class of statistics derived from a theory of semiparametric efficiency. They have become a popular tool in causal inference, including applications to dynamic treatment regimes. The doubly robust estimators for the mean response to a dynamic treatment regime may be conceived through the augmented inverse probability weighted (AIPW) estimating function, defined as the sum of the inverse probability weighted (IPW) estimating function and an augmentation term. The IPW estimating function of the causal estimand (...) via marginal structural model is defined as the complete-case score function for those subjects whose treatment sequence is consistent with the dynamic regime in question divided by the probability of observing the treatment sequence given the subject's treatment and covariate histories. The augmentation term is derived by projecting the IPW estimating function onto the nuisance tangent space and has mean-zero under the truth. The IPW estimator of the causal estimand is consistent if (i) the treatment assignment mechanism is correctly modeled and the AIPW estimator is consistent if either (i) is true or (ii) nested functions of intermediate and final outcomes are correctly modeled.Hence, the AIPW estimator is doubly robust and, moreover, the AIPW is semiparametric efficient if both (i) and (ii) are true simultaneously. Unfortunately, DR estimators can be inferior when either (i) or (ii) is true and the other false. In this case, the misspecified parts of the model can have a detrimental effect on the variance of the DR estimator. We propose an improved DR estimator of causal estimand in dynamic treatment regimes through a technique originally developed by [4] which aims to mitigate the ill-effects of model misspecification through a constrained optimization.In addition to solving a doubly robust system of equations, the improved DR estimator simultaneously minimizes the asymptotic variance of the estimator under a correctly specified treatment assignment mechanism but misspecification of intermediate and final outcome models. We illustrate the desirable operating characteristics of the estimator through Monte Carlo studies and apply the methods to data from a randomized study of integrilin therapy for patients undergoing coronary stent implantation. The methods proposed here are new and may be used to further improve personalized medicine, in general. (shrink)

It is worthwhile to search for forms of coding, processing, and learning common to various cortical regions and cognitive functions. Local cortical processors may coordinate their activity by maximizing the transmission of information coherently related to the context in which it occurs, thus forming synchronized population codes. This coordination involves contextual field (CF) connections that link processors within and between cortical regions. The effects of CF connections are distinguished from those mediating receptive field (RF) input; it is shown how CFs (...) can guide both learning and processing without becoming confused with the transmission of RF information. Simulations explore the capabilities of networks built from local processors with both RF and CF connections. Physiological evidence for synchronization, CFs, and plasticity of the RF and CF connections is described. Coordination via CFs is related to perceptual grouping, the effects of context on contrast sensitivity, amblyopia, implicit influences of color in achromotopsia, object and word perception, and the discovery of distal environmental variables and their interactions through self-organization. Cortical computation could thus involve the flexible evaluation of relations between input signals by locally specialized but adaptive processors whose activity is dynamically associated and coordinated within and between regions through specialized contextual connections. Key Words: cell assemblies; cerebral cortex; context; coordination; dynamic binding; epistemology; functional specialization; learning; neural coding; neural computation; neuropsychology; object recognition; perception; reading; self-organization; synaptic plasticity; synchronization. (shrink)

The additional data, perspectives, questions, and criticisms contributed by the commentaries strengthen our view that local cortical processors coordinate their activity with the context in which it occurs using contextual fields and synchronized population codes. We therefore predict that whereas the specialization of function has been the keynote of this century the coordination of function will be the keynote of the next.

Compassion is a prosocial motivation that is critical to the development and survival of the human species. Cultivating compassion involves developing deep wisdom, insight, and understanding into the nature and causes of human suffering; and wisdom and commitment to take positive action to alleviate suffering. This perspective piece discusses how compassion relates to the context of modern technology, which has developed at a rapid pace in recent decades. While advances in digital technology build on humankind’s vast capacity to develop practical (...) tools that promise to enrich our lives and improve our social connections, in reality the effects are often far from benign. The motives underlying the development of many contemporary digital platforms seem rooted in competitiveness and capitalism; while modern social media and online platforms are having a profound and pervasive impact on the mental health and wellbeing of humans around the globe. Nonetheless, digital technology holds considerable potential to promote compassionate insight, wisdom, and prosocial behavior. We reflect on the current state of technology within human society and examine the notion of compassionate technologies; discuss how contemporary paradigm shifts such as the inclusive design movement may be harnessed to build tools and platforms that promote collective good and increase prosocial behavior; and highlight examples of initiatives that are harnessing modern technology to advance democracy, collective knowledge, and personal freedoms and agency. (shrink)

Over the past decade, teaching and learning in virtual worlds has been at the forefront of many higher education institutions around the world. The DEHub Virtual Worlds Working Group (VWWG) consisting of Australian and New Zealand higher education academics was formed in 2009. These educators are investigating the role that virtual worlds play in the future of education and actively changing the direction of their own teaching practice and curricula. 47 academics reporting on 28 Australian higher education institutions present an (...) overview of how they have changed directions through the effective use of virtual worlds for diverse teaching and learning activities such as business scenarios and virtual excursions, role-play simulations, experimentation and language development. The case studies offer insights into the ways in which institutions are continuing to change directions in their teaching to meet changing demands for innovative teaching, learning and research in virtual worlds. This paper highlights the ways in which the authors are using virtual worlds to create opportunities for rich, immersive and authentic activities that would be difficult or not possible to achieve through more traditional approaches. (shrink)

We prove from suitable large cardinal hypotheses that the least weakly compact cardinal can be unfoldable, weakly measurable and even nearly θ\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$${\theta}$$\end{document}-supercompact, for any desired θ\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$${\theta}$$\end{document}. In addition, we prove several global results showing how the entire class of weakly compactcardinals, a proper class, can be made to coincide with the class of unfoldable cardinals, with the class of weakly measurable cardinals or (...) with the class of nearly θκ\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$${\theta_\kappa}$$\end{document}-supercompact cardinals κ\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$${\kappa}$$\end{document}, for nearly any desired function κ↦θκ\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$${\kappa\mapsto\theta_\kappa}$$\end{document}. These results answer several questions that had been open in the literature and extend to these large cardinals the identity-crises phenomenon, first identified by Magidor with the strongly compact cardinals. (shrink)

The literature of our day shows experimental scientists to be divided between two schools of thought, now generally called Mechanist and Vitalist. The literature of any day these last 2000 years would tell the same tale, but for occasional changes of name. Where an issue dividing scientists is seen to be an experimental issue, it presents no challenge to the philosopher. His interest is limited to the question, How shall we find out? and where all are agreed as to the (...) way of settling a difference of opinion, he can wait with patience to learn the result. But the very history of this world-old and world-wide conflict between schools of experimental science shows that it never has been, is not now, could never become one whose issue turned on the outcome of this or that experiment; nor in all the 2000 years the conflict has lasted, has science been able to come upon any other type of evidence by which the issue might be settled. As one of a class of similar issues, ancient, pervasive, persistent, the manner of whose decision lies still beyond the grasp of experimental science, this Mechanist-Vitalist controversy gives the philosopher much to think about. (shrink)

Rationale: Deep brain stimulation (DBS) of the hippocampus is proposed for enhancement of memory impaired by injury or disease. Many pre-clinical DBS paradigms can be addressed in epilepsy patients undergoing intracranial monitoring for seizure localization, since they already have electrodes implanted in brain areas of interest. Even though epilepsy is usually not a memory disorder targeted by DBS, the studies can nevertheless model other memory-impacting disorders, such as Traumatic Brain Injury (TBI). Methods: Human patients undergoing Phase II invasive monitoring for (...) intractable epilepsy were implanted with depth electrodes capable of recording neurophysiological signals. Subjects performed a delayed-match-to-sample (DMS) memory task while hippocampal ensembles from CA1 and CA3 cell layers were recorded to estimate a multi-input, multi-output (MIMO) model of CA3-to-CA1 neural encoding and a memory decoding model (MDM) to decode memory information from CA3 and CA1 neuronal signals. After model estimation, subjects again performed the DMS task while either MIMO-based or MDM-based patterned stimulation was delivered to CA1 electrode sites during the encoding phase of the DMS trials. Each subject was sorted (post hoc) by prior experience of repeated and/or mild-to-moderate brain injury (RMBI), TBI, or no history (control) and scored for percentage successful delayed recognition (DR) recall on stimulated vs. non-stimulated DMS trials. The subject’s medical history was unknown to the experimenters until after individual subject memory retention results were scored. Results: When examined compared to control subjects, both TBI and RMBI subjects showed increased memory retention in response to both MIMO and MDM-based hippocampal stimulation. Furthermore, effects of stimulation were also greater in subjects who were evaluated as having pre-existing mild-to-moderate memory impairment. Conclusion: These results show that hippocampal stimulation for memory facilitation was more beneficial for subjects who had previously suffered a brain injury (other than epilepsy), compared to control (epilepsy) subjects who had not suffered a brain injury. This study demonstrates that the epilepsy/intracranial recording model can be extended to test the ability of DBS to restore memory function in subjects who previously suffered a brain injury other than epilepsy, and support further investigation into the beneficial effect of DBS in TBI patients. (shrink)

1. Foreword. Man's every act is an act of faith; generally, an unconscious faith; seldom, an examined faith; never, a faith that by taking thought could have been replaced by assured certainties. All this appears whenever we stop to “rationalize” our conduct. Whatever that conduct may have been, it can be made to appear reasonable only if some propositions are taken to be true, others false. Or, perhaps the more experienced and less exacting mind would feel the reasonableness of its (...) actions to have been as well established as might be, if it could show the premises with which its acts were consistent to be more likely true than false; those with whose truth they were inconsistent, more likely false than true. Either way of putting it points to the one moral; namely, that, apart from incalculable chance, there is nothing but one's judgment in the matter of premises to determine all that one's life can come to know of fruition or frustration. Nothing, then, can be more important to any man than to do all he can to assure the soundness of his reasons for the faith that is in him; i.e. to test the weight of evidence supporting the working hypotheses on which he is willing to act. But to have considered the evidence for the hypotheses on which he has acted or is prepared to act, could be practically useful only to one who had in one way or another come by a sound idea of the evidence on which one should act, if one's actions are not to end in disappointment. The result at which a man's thought on this matter of evidence may have arrived, will constitute his theory of evidence; and the task of constructing the soundest possible theory of evidence is the undertaking of philosophy. (shrink)

4. The Mind's Lawmaking: Critical Idealism. Pleased with something dramatic in the phrase, we often characterize experiment as “a question put to Nature.” But if there be anything flattering to our state in Nature's submission to our questioning, there can be nothing grateful to our heart in her manner of answering. “Are we all to die?” Nature answers, “Yes.” “Will the sun that warmed our fathers last out our children?” Nature answers, “No.” Thus Nature giveth and Nature taketh away; her (...) complaisance ends with letting us know her way with us. (shrink)

Developmental psychology currently faces a deep puzzle: most children before 4 years of age fail elicited-response false-belief tasks, but preverbal infants demonstrate spontaneous false-belief understanding. Two main strategies are available: cultural constructivism and early-belief understanding. The latter view assumes that failure at elicited-response false-belief tasks need not reflect the inability to understand false beliefs. The burden of early-belief understanding is to explain why elicited-response false-belief tasks are so challenging for most children under 4 years of age. The goal of this (...) article is to offer a pragmatic framework whose purpose is to discharge this burden. (shrink)

During the course of the last century it has grown increasingly clear that not all the issues with which an experimental science can be faced are experimental issues. If there were no other ground for this belief, history itself would force upon us some such conviction. For there are differences of opinion dividing men today that have divided men from the earliest times recorded, and in every one of the ages in between the self-same issue will have involved in dissension, (...) not an occasional disputant here and there, but all the best thinkers in all the known sciences of their day. Yet at no time has either party to such strifes been in possession of facts ignored by the other; for had this been the case, the ignorant party must ere now have been driven from the field by force of the facts it ignored. It is fair to suppose that an issue which has come no nearer to solution as century after century added its contribution to the store of human knowledge, cannot depend for its decision on any information to be looked for from the centuries to come. (shrink)