A central problem for the international governance of heritable germline gene editing is that there are important differences in attitudes and values as well as ethical and health care considerations around the world. These differences are reflected in a complicated and diverse regulatory landscape. Several publications have discussed whether reproductive uses would be legally permissible in individual countries and whether clinical applications could emerge in the context of regulatory gaps and gray areas. Systematic comparative studies that explore issues related to (...) the governance of this technology from different national and international perspectives are needed to address the lack of knowledge in this area. In this research report, we contribute to filling this gap by presenting views of stakeholders in the United Kingdom on challenges to the governance of heritable genome editing. We present findings from a multistakeholder study conducted in the United Kingdom between October 2016 and January 2018 and funded by the Wellcome Trust. This research included interviews, literature analysis, and a workshop. We involved leading U.K. scientists, in vitro fertilization clinicians, and representatives from regulatory bodies, patient organizations, and other civil societal organizations, as well as fertility companies. Part one of this article explores stakeholder perceptions of possible global developments in heritable genome editing and associated risks and governance challenges. Part two presents a range of policy options that were generated during the workshop in relation to the challenges discussed in part one. (shrink)

Islamic philosophy; Arab philosophy; idealism.

al-Qism al-awwal. al-Iftirāḍ al-musbaq fī al-lisānīyāt al-ḥadīthah -- al-qism al-thānī. al-Iftirāḍ al-musbaq fī al-turāth al-ʻarabī wa-al-islāmī.

Bioethical debates on the use of human embryos and oocytes for stem cell research have often been criticized for the lack of empirical insights into the perceptions and experiences of the women and couples who are asked to donate these tissues in the IVF clinic. Empirical studies that have investigated the attitudes of IVF patients and citizens on the donation of their embryos and oocytes have been scarce and have focused predominantly on the situation in Europe and Australia. This article (...) examines the viewpoints on the donation of embryos for stem cell research among IVF patients and students in China. Research into the perceptions of patients is based on in-depth interviews with IVF patients and IVF clinicians. Research into the attitudes of students is based on a quantitative survey study. The empirical findings in this paper indicate that perceptions of the donation of human embryos for stem cell research in China are far more diverse and complex than has commonly been suggested. Claims that ethical concerns regarding the donation and use of embryos and oocytes for stem cell research are typical for Western societies but absent in China cannot be upheld. The article shows that research into the situated perceptions and cultural specificities of human tissue donation can play a crucial role in the deconstruction of politicized bioethical argumentation and the assumptions about “others” that underlie socio-ethical debates on the moral dilemmas of technology developments in the life sciences. (shrink)

The emerging consensus in the philosophy of cognition is that cognition is situated, i.e., dependent upon or co-constituted by the body, the environment, and/or the embodied interaction with it. But what about emotions? If the brain alone cannot do much thinking, can the brain alone do some emoting? If not, what else is needed? Do (some) emotions (sometimes) cross an individual's boundary? If so, what kinds of supra-individual systems can be bearers of affective states, and why? And does that make (...) emotions ?embedded? or ?extended? in the sense cognition is said to be embedded and extended? Section 2 shows why it is important to understand in which sense body, environment, and our embodied interaction with the world contribute to our affective life. Section 3 introduces some key concepts of the debate about situated cognition. Section 4 draws attention to an important disanalogy between cognition and emotion with regard to the role of the body. Section 5 shows under which conditions a contribution by the environment results in non-trivial cases of ?embedded? emotions. Section 6 is concerned with affective phenomena that seem to cross the organismic boundaries of an individual, in particular with the idea that emotions are ?extended? or ?distributed.? (shrink)

Several theories of emergence will be distinguished. In particular, these are synchronic, diachronic, and weak versions of emergence. While the weaker theories are compatible with property reductionism, synchronic emergentism and strong versions of diachronic emergentism are not. Synchronice mergentism is of particular interest for the discussion of downward causation. For such a theory, a system's property is taken to be emergent if it is irreducible, i.e., if it is not reductively explainable. Furthermore, we have to distinguish two different types of (...) irreducibility with quite different consequences: If, on the one hand, a system's property is irreducible because of the irreducibility of the system's parts' behavior on which the property supervenes, we seem to have a case of "downward causation". This kind of downward causation does not violate the principle of the causal closure of the physical domain. If, on the other hand, a systemic property is irreducible because it is not exhaustively analyzable in terms of its causal role, downward causation is not implied. Rather, it is dubitable how unanalyzable properties might play any causal role at all. Thus, epiphenomenalism seems to be implied. The failure to keep apart the two kinds of irreducibility has muddled recent debate about the emergence of properties considerably. (shrink)

Zusammenfassung Eine Karriere im Hochleistungssport ist mit hohen zeitlichen Belastungen verbunden. Da die Spitzensport- Karriere lebenszeitlich beschränkt ist und in der Regel in der vierten Lebensdekade beendet wird, stellt sich die Frage nach den Auswirkungen eines Engagements im Hochleistungssport auf die Berufskarriere. Hierzu wurden im Rahmen einer quantitativ orientierten Kohortenanalyse ehemalige Spitzensportler zu ihrem beruflichen Werdegang und möglichen Einflussfaktoren des Hochleistungssports retrospektiv befragt. Die Befunde der beiden Teiluntersuchungen zeigen, dass die hohen zeitlichen Anforderungen des Spitzensports den beruflichen Werdegang nur zum (...) Teil beeinträchtigen. Dies gilt nicht nur für sehr erfolgreiche Sportler, sondern auch für Hochleistungssportler, die weniger erfolgreich sind, sowie für Profisportler, die besonders intensiv in das System Hochleistungssport eingebunden sind. Dabei wirken sich Faktoren, wie institutionelle Unterstützungsmaßnahmen, Bekanntheit und soziale Kontakte sowie die Chance im Berufsfeld Spitzensport zu arbeiten, positiv auf die Berufskarriere aus. Allerdings haben sich aufgrund der Professionalisierung des Hochleistungssports die Risiken im kohortenspezifischen Vergleich vergrößert. (shrink)

In this paper, we argue that the concept of environmental scaffolding can contribute to a better understanding of our affective life and the complex manners in which it is shaped by environmental entities. In particular, the concept of environmental scaffolding offers a more comprehensive and less controversial framework than the notions of embeddedness and extendedness. We contribute to the literature on situated affectivity by embracing and systematizing the diversity of affective scaffolding. In doing so, we introduce several distinctions that provide (...) classifications of different types of environmentally scaffolded affectivity. Furthermore, we differentiate eight dimensions that allow us to evaluate the quality and effectivity of scaffolds in particular applications. On that basis, we develop a taxonomy using paradigmatic examples of affective scaffolding. This taxonomy enriches the current debate by emphasizing distinctions that are often conflated and by identifying fields of application that are commonly overlooked. (shrink)

The concept of emergence is widely used in both the philosophy of mind and in cognitive science. In the philosophy of mind it serves to refer to seemingly irreducible phenomena, in cognitive science it is often used to refer to phenomena not explicitly programmed. There is no unique concept of emergence available that serves both purposes.

Justice (Philosophy); history; 20th century.

Often, the behavior of animals can be better explained and predicted, it seems, if we ascribe the capacity to have beliefs, intentions, and concepts to them. Whether we really can do so, however, is a debated issue. Particularly, Donald Davidson maintains that there is no basis in fact for ascribing propositional attitudes or concepts to animals. I will consider his and rival views, such as Colin Allen's three-part approach, for determining whether animals possess concepts. To avoid pure theoretical debate, however, (...) I will test these criteria using characteristic examples from ethology that depict a broad range of animal behavior. This will allow us to detect a series of gradations in animals' capacities, in the course of which we can think over what would count for or against an attribution of concepts and propositional attitudes to them in each single case. Self-conceit is our natural hereditary disease. Of all creatures man is the most wretched and fragile, and at once the most supercilious. ... It is by this conceit that man arrogates to himself ... divine properties, that he segregates himself from the mass of other creatures and raises himself above them .. (shrink)

We generalise the concept of clique width to structures of arbitrary signature and cardinality. We present characterisations of clique width in terms of decompositions of a structure and via interpretations in trees. Several model-theoretic properties of clique width are investigated including VC-dimension and preservation of finite clique width under elementary extensions and compactness.

Review by: Achim Blumensath The Bulletin of Symbolic Logic, Volume 19, Issue 3, Page 394-396, September 2013.

The goal of this paper is to examine moods, mostly in comparison to emotions. Nearly all of the features that allegedly distinguish moods from emotions are disputed though. In a first section I comment on duration, intentionality, and cause in more detail, and develop intentionality as the most promising distinguishing characteristic. In a second section I will consider the huge variety of moods, ranging from shallow environmentally triggered transient moods to deep existential moods that last much longer. I will explore (...) what their sources are, and how they impact one another, other affective processes, and our being in the world. I follow several eminent emotion researchers and try to carve out their insights, many seemingly mutually excluding each other. As it will turn out, most of them are, in fact, not excluding each other, but contribute to a layered picture of moods that fits well in between emotions and personality traits. Eventually, I will shortly discuss what we can do with our moods. (shrink)

Während es im moralisch-politischen Diskurs geradezu unkontrovers ist, dass Toleranz eine eminent wichtige Rolle für ein friedliches Zusammenleben von Menschen in pluralistischen Gesellschaften spielt, ist es alles andere als klar, was Toleranz überhaupt ist. Insbesondere die häufig anzutreffende Auffassung, dass es ‚Paradoxien‘ der Toleranz gäbe, sowie die in der Literatur immer von Neuem auftauchende Vexierfrage, ob Toleranz auch den Feinden der Toleranz gelten kann oder muss, sind deutliche Anzeichen dafür, dass es kein stabiles Verständnis der Natur dieser Einstellung gibt. Das (...) Problem ist nicht zuletzt ein methodologisches. Ich stelle zunächst einige Adäquatheitsbedingungen für eine Theorie der Toleranz auf, und argumentiere dann, dass eine Theorie der Toleranz als eine moralpsychologische Theorie vom normativen Begriff der Tolerierbarkeit frei zu halten ist. Nach der hier vorgeschlagenen Theorie besteht das Herzstück der Toleranz in einer verhaltenswirksamen Kontrolle moralischer Aversionen. Diese Theorie erfüllt die Adäquatheitsbedingungen für Theorien der Toleranz und wird von ihnen sogar erzwungen. Auf der Grundlage der erzielten Ergebnisse, erläutere ich dann Sinn und Rechtfertigung der Toleranzforderung und skizziere ihren Ort innerhalb der Ethik. (shrink)

This article examines for the first time the jihadist global hegemonic masculinity of Osama bin Laden. Based on Bin Laden’s public statements translated into English, the authors examine how in the process of constructing a rationale for violent attacks primarily against the United States, he simultaneously and discursively formulates a jihadist global hegemonic masculinity. The research adds to the growing interest in discursive global hegemonic masculinities, as well as jihadist masculinities in the Middle East, by scrutinizing how Bin Laden’s jihadist (...) global hegemonic masculinity is produced in and through his public statements. The authors close their discussion by demonstrating how Bin Laden’s discursive practices are embedded in a clash of competing global hegemonic masculinities on the world stage. (shrink)

According to Kant, the moral worth of an action depends on its maxim. As he explains, particularly in the Groundwork, moral worth accrues to an action when the action rests on a maxim selected for its accordance with the moral law. With respect to Religion, however, Kant modifies his understanding of the moral worth of actions. He now expresses the view that an agent acts morally worthy only if he possesses a moral Gesinnung as a character trait. According to this (...) opinion, only such persons can act in a manner that has moral worth who own a good Gesinnung and seek to express it in their actions. But to be in possession of a good Gesinnung depends, according to Kant, on strict conditions that ordinary actors will not realistically be able to fulfil. This accords with Kant's verdict that moral progress has not yet taken place because the conversion in Gesinnung that it would require is still outstanding. (shrink)

This article focuses on existential feelings. To begin with, it depicts how they differ from other affective phenomena and what type of intentionality they manifest. Furthermore, a detailed analysis shows that existential feelings can be subdivided, first, into elementary and nonelementary varieties, and second, into three foci of primary relatedness: oneself, the social environment, and the world as such. Eventually, five strategies of emotion regulation are examined with respect to their applicability to existential feelings. In the case of harmful existential (...) feelings, it turns out that none seems fitting except one, attentional deployment. (shrink)

Several species concepts are generally discussed and evaluated. Then the new definition, the pheno-genetic species concept, is developed; it reads: a species is the largest possible, regional evolutionary unit of pheno-genetically equal (in the typical, specific characters), identically reproducing demes. It is separated from sympatric species by a reproductive isolation that guarantees a unique evolution, an evolution different from that of other species and sufficiently uninfluenced, and that is accompanied by another distinctive pheno-genetic gap. It is separated from allopatric species (...) by a distinctive pheno-genetic gap that - in the case of missing reproductive isolation in bisexual forms — allows the conclusion that such an isolation would have developed, if the species had been sympatric with the allopatric species. This definition is applied to several situations of evolution. The effects of the concepts on the classification of lizards are demonstrated by examples. (shrink)

Research on bodies and sexualities has long debated ideas about choice, agency, and power, particularly as women conform to, or rebel against, traditional social scripts about femininity and heterosexuality. In this study, I have used responses from 34 college women who completed an extra credit assignment in a women’s studies class that asked them to reject social norms and grow out their leg and underarm hair for a period of 10 weeks. Responses reveal that women confronted direct and anticipated homophobia (...) and heterosexism from others as well as hostility for rejecting traditional norms of femininity. Heterosexual women regularly encountered demands that they acquire permission to grow body hair from their male partners, while queer and bisexual women expressed reluctance about further “outing” themselves via their body hair. I consider implications for linking sexual identity discrimination and body hair practices, and for imagining bodies as sites of resistance inside and outside of pedagogical settings. (shrink)

Moving from viruses, vaccines, and copycat murder to gay panics, xenophobia, and psychopaths, _Transforming Contagion_ energetically fuses critical humanities and social science perspectives into a boundary-smashing interdisciplinary collection on contagion. The contributors provocatively suggest contagion to be as full of possibilities for revolution and resistance as it is for the descent into madness, malice, and extensive state control. The infectious practices rooted in politics, film, psychological exchanges, social movements, the classroom, and the circulation of a literary text or meme on (...) social media compellingly reveal patterns that emerge in those attempts to re-route, quarantine, define, or even exacerbate various contagions. (shrink)

Certification is a crucial part of the organic farming system to protect the integrity of the whole organic sector. Process-oriented on-site auditing by skilled inspectors is the central element of the certification procedure to protect the organic sector against fraud. However, little is known about the role of the inspectors in the certification scheme. In recent years, the requirements and challenges for the organic certification system have changed significantly. The aim of the present study is to get insights into strategies (...) and action patterns used by organic inspectors and thus to better understand their behaviour. Due to the exploratory character of the study, a qualitative approach was chosen. Twenty narrative expert interviews with organic inspectors were conducted. The evaluation was carried out with the narration analysis, which was basis for a typology analysis. The results of the study show that all organic inspectors develop strategies and behavioural patterns, which can be structured in two levels: an interpersonal and a professional level. On the interpersonal level, the results indicate that the inspectors’ behaviour patterns lie between goodwill and demonstration of power. At the professional level, the organic inspectors work with a risk or a checklist-oriented control approach. A risk-oriented control is characterised by the intrinsic motivation of the organic inspector to maintain the integrity of the organic sector. Risk-oriented inspectors set a control focus on the detection of fraud. The aspect of personal ethical involvement and interpersonal actions in control systems should be included when considering improvements in the organic sector. (shrink)

This essay explores how indigenous knowledge about plant and animal remedies was gathered, classified, tested, and circulated across wide networks of exchange for natural knowledge between Europe and the Americas. There has been much recent interest in the “bioprospecting” of local natural resources—medical and otherwise—by Europeans in the early modern world and the strategies employed by European travellers, missionaries, or naturalists have been well documented. By contrast, less is known about the role played by indigenous and Creole intermediaries in this (...) process. And yet, the transmission of knowledge between indigenous communities and the European cabinet was neither transparent nor natural, and often involved epistemological, linguistic, and religious obstacles. Drawing on printed and manuscript collections of indigenous remedies, written in colonial Mexico between the sixteenth and the eighteenth centuries, I focus on how local intermediaries, like creoles scholars, sought to overcome such obstacles by observing indigenous uses of remedies, by studying indigenous languages and by producing natural histories and pharmacopoeias in indigenous languages. Ultimately, behind the Creole participation in the transmission of indigenous remedies, one can point to political and cultural interests and to inclusive definitions of knowledge, which cut across oppositions between science and superstition, cabinet and field, centre and periphery. (shrink)