This paper brings Karl Rahner’s understanding of human ex-sistence (L. ex ‘out, forth’ and sistere ‘to stand’)—that is, human ‘standing forth’—to bear upon the phenomenon of black rage in the United States. The reason for this application is the emancipatory potential of Rahner’s transcendental realism, which basically understands human life as a dynamism at once rooted ‘in the world’ and yet called, in obediential potency, to the qualitative ‘more’. Rahner’s anthropological understanding allows for an investigation of the existential struc ture (...) and possibilities of black rage which may benefit black ex-sistence by showing how the dynamism of human life accounts for and justifies this rage as well as what liberating possibilities open up for the enraged. (shrink)

This article argues that economic crises are incompatible with the realisation of non-domination in capitalist societies. The ineradicable risk that an economic crisis will occur undermines the robust security of the conditions of non-domination for all citizens, not only those who are harmed by a crisis. I begin by demonstrating that the unemployment caused by economic crises violates the egalitarian dimensions of freedom as non-domination. The lack of employment constitutes an exclusion from the social bases of self-respect, and from a (...) practice of mutual social contribution crucial to the intersubjective affirmation of one’s status. While this argument shows that republicans must be concerned about economic crises, I suggest a more powerful argument can be grounded in the republican requirement that freedom must be robust. The systemic risk of economic crisis constitutes a threat to the conditions of free citizenship that cannot be nullified using policy mechanisms. As a result, republicans appear to be faced with the choice of revising their commitments or rejecting the possibility that republican freedom can be robustly secured in capitalist societies. (shrink)

While it is a point of agreement in contemporary republican political theory that property ownership is closely connected to freedom as non-domination, surprisingly little work has been done to elucidate the nature of this connection or the constraints on property regimes that might be required as a result. In this paper, I provide a systematic model of the boundaries within which republican property systems must sit and explore some of the wider implications that thinking of property in these terms may (...) have for republicans. The boundaries I focus on relate to the distribution of property and the application of types of property claims over particular kinds of goods. I develop this model from those elements of non-domination most directly related to the operation of a property regime: (a) economic independence, (b) limiting material inequalities, and (c) the promotion of common goods. The limits that emerge from this analysis support intuitive judgments that animate much republican discussion of property distribution. My account diverges from much orthodox republican theory, though, in challenging the primacy of private property rights in the realization of economic independence. The value of property on republican terms can be realized without private ownership of the means of production. (shrink)

While it is a point of agreement in contemporary republican political theory that property ownership is closely connected to freedom as non-domination, surprisingly little work has been done to elucidate the nature of this connection or the constraints on property regimes that might be required as a result. In this paper, I provide a systematic model of the boundaries within which republican property systems must sit and explore some of the wider implications that thinking of property in these terms may (...) have for republicans. The boundaries I focus on relate to the distribution of property and the application of types of property claims over particular kinds of goods. I develop this model from those elements of non-domination most directly related to the operation of a property regime: (a) economic independence, (b) limiting material inequalities, and (c) the promotion of common goods. The limits that emerge from this analysis support intuitive judgments that animate much republican discussion of property distribution. My account diverges from much orthodox republican theory, though, in challenging the primacy of private property rights in the realization of economic independence. The value of property on republican terms can be realized without private ownership of the means of production. (shrink)

Journal of Political Philosophy, EarlyView.

The claim that workers are subject to structural domination in the labor market is a central contention of the recent radical turn in republican political theory, but it remains undertheorized. Two core components—the claim that workers have “no reasonable alternative” to selling their labor to capitalists and the relevance of exposure to potential interference in such cases—remain unclear. Without a more precise specification of the conditions of structural domination, it is difficult to assess how well republican prescriptions minimize it. I (...) develop a revised defense of the central claim through an analysis of these components. I clarify what it is to have reasonable alternatives in the labor market but show that holding such options is insufficient to avoid structural domination. I argue that the dependence at the heart of structural domination can be constituted multifariously and develop an additional criterion directed at capturing such dependence in production. (shrink)

We provide an intuitive motivation for the hyperreal numbers via electoral axioms. We do so in the form of a Socratic dialogue, in which Protagoras suggests replacing big-oh complexity classes by real numbers, and Socrates asks some troubling questions about what would happen if one tried to do that. The dialogue is followed by an appendix containing additional commentary and a more formal proof.

It is a core feature of the conception of freedom as non-domination that freedom requires the absence of exposure to arbitrary power across a range of relevant possible worlds. While this modal robustness is critical to the analysis of paradigm cases of unfreedom such as slavery, critics such as Gerald Gaus have argued that it leads to absurd conclusions, with barely-felt constraints appearing as sources of unfreedom. I aim to clarify the demands of the modal robustness requirement, and offer a (...) reinterpretation of its place in the conceptual framework of freedom as non-domination. I illustrate this point through a discussion of low-probability threats of interference which are central to Gaus’s critique, which I term ‘distant threats’. I argue that those committed to robust conceptions of freedom should still be concerned by these kinds of threats, which will sometimes constitute genuine sources of unfreedom. But rather than leading to absurd conclusions, we should instead view them as diagnostic of deficiencies within existing regimes of non-domination. The challenge posed by distant threats of domination to the republican conception of freedom does not prove it implausible, but illustrates some of its most important insights about the social and economic conditions of free status, and the fragility of that freedom. (shrink)

Political parties have been the subject of a recent resurgent interest among political philosophers, with prominent contributions spanning liberal to socialist literatures arguing for a more positive appraisal of the role of parties in the operation of democratic representation and public deliberation. In this article, I argue for a similar re-evaluation of the role of political parties within contemporary republicanism. Contemporary republicanism displays a wariness of political parties. In Philip Pettit’s paradigmatic account of republican democracy, rare mentions of political parties (...) often stress their tendency to lead to factionalism or corruption. Others working in the republican tradition such as Richard Bellamy and Ian Shapiro provide more extended discussion of the role of parties, but limit their theoretical function to enabling electoral competition. I argue that political parties play a far more significant role in promoting non-domination than this. In addition to enabling electoral competition, I show that political parties are also essential to the effective operation of two other components of republican democracy: contestation and interest-formation. I further argue that understanding political parties in these terms is compatible with republican democracy more generally, addressing the worry that parties will produce factional rather than common-good oriented public decisions. (shrink)

Recent work in republican political theory has identified various forms of domination in the structures and relations of capitalist societies. A notable absence in much of this work is the concept of exploitation, which is generally treated as a predictable outcome of certain kinds of domination. This paper argues that the concept of exploitation can instead be conceived as a form of structural domination, understood in republican terms, and that adopting this conception has important implications for republican attempts to theorize (...) modern capitalist societies. Building on existing domination accounts of exploitation, we argue that exploitation is a form of structurally constituted domination that enables a systemic illegitimate extraction of value. However, in contrast to competing accounts, domination is understood here in the republican terms of subjection to arbitrary power. We show that conceiving of domination in these terms not only makes the concept easily accessible from within a republican framework, but has advantages over competing accounts. Our argument also demonstrates why using the concept of exploitation will be useful for republican theorists. We show that a polity based on exploitative relations of production is antithetical to key republican commitments. These asymmetric power relationships undermine the economic and political independence of citizens and, crucially, constrain the political and economic ends that a polity will be effectively able to pursue. As such, exploitation should be a central preoccupation of republican political economy. (shrink)

In the history of palliative care, all roads lead back to Dame Cicely Saunders, a remarkable social worker/nurse/physician who promoted the concept of total pain and founded the first modern hospic...

In this wide-ranging conversation, Michael Hardt reflects on recent transformations within Empire. Several unique themes emerge concerning power and pedagogy as they intersect with subjectivity and global crisis. Drawing on the common in conjunction with the tradition of love in education uncovers a different path that attends to today’s real political, ecological, and social needs. Finally, a focus on collectivity points to a possible strategy—collective intellectuality—for educators to revise traditional notions of leadership to encourage more ethical, democratic, and sustainable futures. (...) Yet, what this looks like in practice remains for us to imagine. (shrink)

Hackles have been raised in biosemiotic circles by T. L. Short’s assertion that semiosis, as defined by Peirce, entails “acting for purposes” and therefore is not found below the level of the organism (2007a:174–177). This paper examines Short’s teleology and theory of purposeful behavior and offers a remedy to the disagreement. Remediation becomes possible when the issue is reframed in the terms of the complexity sciences, which allows intentionality to be understood as the interplay between local and global aspects of (...) a system within a system. What is called “acting for purposes” is not itself a type of behavior so much as a relationship between a dynamic system that “exists for a purpose” and its microprocesses that “serve purposes.” The “intentional object” of philosophy is recast here as the holistic self-organized dynamics of a system, which exists for the purpose of self-maintenance, and that constrains the parts’ behaviors, which serve the purpose of forming the system. (A “system” can be any emergent, e.g. an abiotic form, an adapted species, a self, a conditioned response, thought, or a set of ideas.) The self-organized whole, which is represented to the parts in their own constrained behaviors, assumes the guiding function so long attributed to the mysterious “intentional object.” If emergent self-causation is not disallowed, creative originality, as well as directionality, becomes part of the definition of purposeful behavior. Thus, key tools used here, required for understanding emergence, come from poetics rather than semoitics. In the microprocesses of self-organization, I find what I call “accidental” indices and icons — which are poetic in the sense that they involve mere metonymic contiguity and metaphoric similarity — and which are preferentially selected under constrained conditions allowing radically new connections to habituate into an “intentional” self-organized system that, not coincidentally, has some of the emergent characteristics of a conventional symbolic system. (shrink)

We characterize þ-independence in a variety of structures, focusing on the field of real numbers expanded by predicate defining a dense multiplicative subgroup, G, satisfying the Mann property and whose pth powers are of finite index in G. We also show such structures are super-rosy and eliminate imaginaries up to codes for small sets.

Although research into the biosemiotic mechanisms underlying the purposeful behavior of brainless living systems is extensive, researchers have not adequately described biosemiosis among neurons. As the conscious use of signs is well-covered by the various fields of semiotics, we focus on subconscious sign action. Subconscious semiotic habits, both functional and dysfunctional, may be created and reinforced in the brain not necessarily in a logical manner and not necessarily through repeated reinforcement. We review literature that suggests hypnosis may be effective in (...) changing subconscious dysfunctional habits, and we offer a biosemiotic framework for understanding these results. If it has been difficult to evaluate any psychological approach, including hypnosis, this may be because contemporary neuroscience lacks a theory of the sign. We argue that understanding the fluid nature of representation in biological organisms is prerequisite to understanding the nature of the subconscious and may lead to more effective of treatments for dysfunctional habits developed through personal experience or culture. (shrink)

It is a landmark theorem of McKinsey and Tarski that if we interpret modal diamond as closure, then $$\mathsf S4$$ S4 is the logic of any dense-in-itself metrizable space. The McKinsey–Tarski Theorem relies heavily on a metric that gives rise to the topology. We give a new and more topological proof of the theorem, utilizing Bing’s Metrization Theorem.

In this special issue, our objective is to clarify what biosemioticians may mean insofar as they claim that living systems are capable of making choices or that biosemiotic interpretations are partially indeterminate. A number of different senses of the term “chance” are discussed as we move toward a consensus. We find that biosemiosic chance may arise out of conditions involving quantum indeterminacy, randomness, deterministic chaos, or unpredictability, but biosemiosic chance is mainly due to the fact that living entities invest their (...) environments with different meanings and values, which are not inherent in the material aspects. Accordingly, interpretive responses are in part self-determined. A self-determined interpretation may be thought of as a process in which localized biases constrain the probabilities of the outcomes of the interactions between an agent and its environment. The agent’s internal formal constraints that are defined by similarity and proximity are relative and, as such, vague, and thus interpretation may be somewhat underdetermined and involve an element of chance. (shrink)

Globalization and cosmopolitanism, on the one hand, and autarchy and nationalism, on the other, are two extremes between which humankind is destined to balance constantly, due to diversity and the natural confrontation of various cultural and civilizational systems by which it is represented. At the same time, globalization and cosmopolitanism are natural phenomena and are the most important characteristics of social development. That is why we should not put obstacles in the way of their dissemination and rooting in social life, (...) but to aim at deeper understanding of their essence and what is hidden behind them in order, preventing ourselves from rash evaluations and one-sided conclusions, to contribute to the formation of a stable and just global world. (shrink)

The article discusses the meanings of life and value priorities of the post- Soviet society. The author argues that, at present, there are symptoms of a global ideological crisis in the world, that the West does not have its own vision of where and how to move on and has no understanding of the future. Unfortunately, most of the post-Soviet countries do not have such vision as well. In these conditions, there are mistrust, confusion, paradoxical manifestation of human consciousness. The (...) main meanings that determine our life-world are: the desire of citizens for social justice and social security, the desire to figure out and understand the basic values of modern society, how honestly and equally the authorities act toward their fellow citizens, and to what extent they reflect their interests. The meanings of life, which are the answers to the challenges of the time, are embodied in the cultural code of each nation, state. The growth points of new values, which will become the basis for the future sustainable development of a new civilization, have yet to be discovered in the systemic transformative changes of the culture. In this process, the emergence of a new system of values that governs human life is inevitable. However, modern technology brings new troubles to humans. It has provided wide opportunities for informational violence and public consciousness manipulation. Nowadays, the scenario that is implemented in Western consumer societies claims to be the dominant scenario. Meanwhile, today there is no country in the world that is a role model, there is no ideal that others would like to borrow. Most post-Soviet states failed to advance their societies to more decent levels of economic development, to meet the challenges of the modern information age, and to provide the population with new high living standards. Therefore, in conditions of growing confrontation, we should realistically understand the world and be ready to implement changes that will ensure sustainable development of the state and society without losing our national identity. (shrink)

The article discusses the development of modern society. In the author’s opinion, the prediction of society development is not possible due to the spontaneity of social processes. The contemporary social development is characterized by transition values: strategic instability, permanent crisis, decay of morality, degradation of the ecological environment, increase of international terrorism, danger of nuclear war, etc. Each epoch, including an epoch of uncertainty, gives rise to its own mechanisms for regulating world development, which are based on the historical memory (...) of mankind, on the acknowledgment of the value of peaceful coexistence and the acceptance of human life as the highest value. Preventing war is the main value of world development. The crucial decisions of country’s further development are dictated by the security of the state. The author demonstrates that in our time the ideal of progress evolves from the concept of accelerated innovation changes into the ideal of sustainable development, which presumes the formation of new values as a condition for the transition to new strategies of civilizational development. The current system of economic growth has its own value foundation – a consumer society. The preservation of a consumer society or the transition to alternative development scenarios largely depend on the achievements of the social sciences and humanities. The future will come without our will, but are we ready to accept this alien and unpredictable future? That is why we cannot passively await the future. The future will not arise by itself, the future will be what we make it. (shrink)

_Between Past Orthodoxies and the Future of Globalization_ provides essays in English by leading thinkers in Russia in philosophy, political theory, and related fields. Their essays articulate Russian perspectives on the key global issues being faced internationally and in Russia.

Intent and mitigating circumstances play a central role in moral and legal assessments in large-scale industrialized societies. Al- though these features of moral assessment are widely assumed to be universal, to date, they have only been studied in a narrow range of societies. We show that there is substantial cross-cultural variation among eight traditional small-scale societies (ranging from hunter-gatherer to pastoralist to horticulturalist) and two Western societies (one urban, one rural) in the extent to which intent and mitigating circumstances influence (...) moral judgments. Although participants in all societies took such factors into account to some degree, they did so to very different extents, varying in both the types of considerations taken into account and the types of violations to which such considerations were applied. The particular patterns of assessment characteristic of large-scale industrialized societies may thus reflect relatively recently culturally evolved norms rather than inherent features of human moral judgment. (shrink)

Long noncoding RNAs have been described in cell lines and various whole tissues, but lncRNA analysis of development in vivo is limited. Here, we comprehensively analyze lncRNA expression for the adult mouse subventricular zone neural stem cell lineage. We utilize complementary genome-wide techniques including RNA-seq, RNA CaptureSeq, and ChIP-seq to associate specific lncRNAs with neural cell types, developmental processes, and human disease states. By integrating data from chromatin state maps, custom microarrays, and FACS purification of the subventricular zone lineage, we (...) stringently identify lncRNAs with potential roles in adult neurogenesis. shRNA-mediated knockdown of two such lncRNAs, Six3os and Dlx1as, indicate roles for lncRNAs in the glial-neuronal lineage specification of multipotent adult stem cells. Our data and workflow thus provide a uniquely coherent in vivo lncRNA analysis and form the foundation of a user-friendly online resource for the study of lncRNAs in development and disease. © 2013 Elsevier Inc. (shrink)

The author analyzes the problem of social progress in the context of the historical stages of development: savagery – barbarism – civilization. I show how, under the influence of the Great Geographical Discoveries, the variety of continental empires was replenished with maritime (colonial) empires. Globalization has given them a powerful impetus for their development. Then, from the XX century, empires ceased to meet the requirements of the changed times. The empire, as a form of organization of social life, turned out (...) to be ineffective in the modern global world and entered into an acute phase of antagonistic contradictions with it. (shrink)

The article analyzes the main parameters of the modern world development, its architectonics and the most important development trends. Modern communications and principles of interaction of various social systems are also considered. As a result, the most significant cultural-cum-civilizational systems are distinguished – the West, China, the Islamic world and Russia, which represent four global trends or four vectors of power that fundamentally affect the current state and prospects of world development. It is emphasized that the West and China have (...) a global strategy, provided by objective circumstances. The Islamic world and Russia occupy an important geopolitical position and also have a special status in the global world. (shrink)

It is a landmark theorem of McKinsey and Tarski that if we interpret modal diamond as closure, then \ is the logic of any dense-in-itself metrizable space. The McKinsey–Tarski Theorem relies heavily on a metric that gives rise to the topology. We give a new and more topological proof of the theorem, utilizing Bing’s Metrization Theorem.

Name der Zeitschrift: Byzantinische Zeitschrift Jahrgang: 109 Heft: 2 Seiten: 809-820.

Bio-art epitomizes a coalescence of art and sciences. It is an emerging contemporary artistic practice that uses a wide range of traditional artistic media interwoven with new artistic media that are biological in nature. This includes molecules, genes, cells, tissues, organs, living organisms, ecological niches, landscapes and ecosystems. In addition, bio-art expands into conceptual art using biological processes such as growth, cell division, photosynthesis and concepts of the origin of life and evolution, explaining them as new artistic media. In this (...) time of global challenges, bio-art communicates thoughts and feelings that involve relationships between the artist, science, public and the biological organism or biological concept. This article reviews the major challenges and driving forces that contributed to emerging biology-centered art and design. (shrink)

Within ZFC, we develop a general technique to topologize trees that provides a uniform approach to topological completeness results in modal logic with respect to zero-dimensional Hausdorff spaces. Embeddings of these spaces into well-known extremally disconnected spaces then gives new completeness results for logics extending S4.2.

We prove that the existence of a measurable cardinal is equivalent to the existence of a normal space whose modal logic coincides with the modal logic of the Kripke frame isomorphic to the powerset of a two element set.

This book provides brief expositions of the central concepts in the field of Global Studies. Former President of the Soviet Union Mikhail Gorbachev says, “The book is intelligent, rich in content and, I believe, necessary in our complex, turbulent, and fragile world.” 300 authors from 50 countries contributed 450 entries. The contributors include scholars, researchers, and professionals in social, natural, and technological sciences. They cover globalization problems within ecology, business, economics, politics, culture, and law. This interdisciplinary collection provides a basis (...) for understanding the concepts and methods within global studies and for accessing lengthier and more technical research in the field. The articles treat such important topics as the biosphere, ozone depletion, land resources and pollution, world health challenges, education, global modeling, sustainable development, war, weapons of mass destruction, and terrorism. The book also promotes academic cooperation, political dialogue, and mutual understanding across diverse traditions and national identities that are needed to engage successfully the many daunting challenges of globalization. (shrink)

_Philosophical Aspects of Globalization_ is a collection of essays by leading contemporary Russian philosophers and scholars concerned with addressing pressing questions of globalization and its impact from a philosophical point of view.

Some RNases possess preferential cytotoxicity against malignant cells. The best known of these RNases, onconase, was isolated from frog oocytes and is in clinical trials as anticancer therapy. Here we propose an alternative platform for anticancer therapy based on T1 RNases of microbial origin, in particular binase from Bacillus intermedius and RNase Sa from Streptomyces aureofaciens. We discuss their advantages and the most promising directions of research for their potential clinical applications. BioEssays 30:781–790, 2008. © 2008 Wiley Periodicals, Inc.