DNA methylation plays a role in the repression of gene expression in animal cells. In the mouse preimplantation embryo, most genes are unmethylated but a wave of de novo methylation prior to gastrulation generates a bimodal pattern characterized by unmethylated CpG island‐containing housekeeping genes and fully modified tissue‐specific genes. Demethylaton of individual genes then takes place during cell type specific differentiation, and this demodification may be a required step in the process of transcriptional activation. DNA modification is also involved in (...) the maintenance of gene repression on the inactive X chromosome in female somatic cells and the marking of parental alleles at genomically imprinted gene loci. (shrink)

Our approach is based on a tri-partite method of integrating psychodynamic hypotheses, cognitive subliminal processes, and psychophysiological alpha power measures. We present ten social phobic subjects with three individually selected groups of words representing unconscious conflict, conscious symptom experience, and Osgood Semantic negative valence words used as a control word group. The unconscious conflict and conscious symptom words, presented subliminally and supraliminally, act as primes preceding the conscious symptom and control words presented as supraliminal targets. With alpha power as a (...) marker of inhibitory brain activity, we show that unconscious conflict primes, only when presented subliminally, have a unique inhibitory effect on conscious symptom targets. This effect is absent when the unconscious conflict primes are presented supraliminally, or when the target is the control words. Unconscious conflict prime effects were found to correlate with a measure of repressiveness in a similar previous study (Shevrin et al., 1992, 1996). Conscious symptom primes have no inhibitory effect when presented subliminally. Inhibitory effects with conscious symptom primes are present, but only when the primes are supraliminal, and they did not correlate with repressiveness in a previous study (Shevrin et al., 1992, 1996). We conclude that while the inhibition following supraliminal conscious symptom primes is due to conscious threat bias, the inhibition following subliminal unconscious conflict primes provides a neurological blueprint for dynamic repression: it is only activated subliminally by an individual's unconscious conflict and has an inhibitory effect specific only to the conscious symptom. These novel findings constitute neuroscientific evidence for the psychoanalytic concepts of unconscious conflict and repression, while extending neuroscience theory and methods into the realm of personal, psychological meaning. (shrink)

In two experiments subjects attempted to identify words presented below the objective threshold using two task strategies emphasizing either allowing a word to pop into their heads or looking carefully at the stimulus field . Words were selected to represent both meaningful and structural dimensions. We also asked subjects to indicate their strategy preference and to rate their motivation to perform well. In the absence of conscious perception, both strategy preference and word meaning interacted with strategy condition, mediating the accuracy (...) of subjects′ direct word identification judgments. Motivation also mediated performance. Word structure had no effect. Unconscious perception manifested only in the pop condition, underscoring the importance of task strategy in determining whether subliminal effects are observed. A follow-up control experiment using sham flashes demonstrated that strategy preference and motivation effects were not artifacts resulting from performance feedback cues. (shrink)

Chomsky, meanwhile, has long expressed great reluctance even to recommend reading material to his audiences, let alone how they ought to vote, on the basis that they shouldn’t be substituting his judgment for their own. At the same time he has equally consistently maintained that elections are an elaborate PR charade unworthy of more than the briefest attention, a stance he somehow considers consistent with the petition’s call to put the presidential elections at the top of our list of concerns (...) this year. Fortunately, these two fine dissidents haven’t joined in the vilification of Nader that has become all the rage among Democrats and all-too-many progressives, at least not yet. (shrink)

In this volume experienced educators discuss the task of teaching ethics to professionals, managers and others who are practically-minded; and expert contributors explore the nature of ethical survival in contemporary society and the range of organizations it encompasses.

This volume includes works by authors from the global South and contributions about ethical issues in the global South, including the responses to famine in East Africa, India and Indonesia, and the applicability of international guidelines and ethical frameworks in South Africa.

The latest volume of Research in Ethical Issues in Organizations examines a range of contemporary issues in applied and professional ethics and explores the unique role of organizational ethics in creating and sustaining a pluralistic, free enterprise economy.

This volume looks at the role of organizations in society, the international and multidisciplinary scope of business ethics, and the importance of narrative.

The ethics of war and peace -- Levinas and business ethics in the 'War on terror' -- The ten commandments of working robots in organisations : from history to the future of robot ethics, legislation, and management -- Closing the gap between promises and outcomes : how moral frameworks contribute to the realisation of United Nations deployment objectives -- Visualising success : the wisdom of John Wooden -- Rushing fools and wise women : tales for organisations aiming to improve lives (...) -- Strong identification, weak ideology, organisational culture or all : unethical pro-organisational behaviour in India -- Forsaking the mean for the extreme : a response to Provis. (shrink)

Van Selst and Merikle argued that the critical Preference × Strategy interaction findings could be alternatively explained by positing individual differences as a function of preference and strategy. They further argued that ruling out conscious perception depends on making the exhaustiveness assumption. We argue that the inhibitory effects satisfy objective threshold criteria regardless of possible individual differences in thresholds. We further suggest that the inhibitory findings are inherently incompatible with the conscious perception explanation and that therefore we do not need (...) to make the exhaustiveness assumption. We thus stand by our original conclusion that subliminal perception at the objective threshold has been demonstrated. (shrink)

While some conclude from the revolutions of 1989 that socialism is dead, interest in socialism continues because of persisting problems of contemporary capitalism. In this exciting text, Michael W. Howard offers critiques of liberal, communitarian, postmodern and some Marxist perspectives in order to develop a 'left-liberal' defense of a model of self-managed market socialism that includes a basic income for all. Specific applications of his view include analyses of its implications for the global marketplace, the changing nature of (...) workplaces, and media restructuring and ownership. This work is sure to be of interest to social scientists, public policy makers, and economists as well as to feminists, ecologists, and others concerned with how market socialism is relevant to their social issues. (shrink)

Preprinted in God and the Problem of Evil (Blackwell 2001), ed. William Rowe. In this article, we reply to Bill Rowe's "Evil is Evidence Against Theistic Belief" in Contemporary Debates in Philosophy of Religion (Blackwell 2003).

Standard economic models predict large economic gains from liberalized immigration. However, those models assume that immigrants would have no effect on the causes of economic prosperity in destination countries. Immigrants could reduce the quality of economic institutions in destination countries, thus undermining the economic gains from liberalized immigration. This paper uses an epidemiological model to investigate how heterogeneously distributed immigrants affected the economic institutions of American states over the 1980–2010 period under the assumption that institutions are highly responsive to changes (...) in the immigrant population. We find that state economic institutions do not change much in response to immigrants. (shrink)

Proposals for a universal basic income have reemerged in public discourse for a variety of reasons. Marx’s critique of exploitation suggests two apparently opposed positions on a basic income. On the one hand, a basic income funded from taxes on labor would appear to be exploitative of workers. On the other hand, a basic income liberates everyone from the vulnerable condition in which one is forced to sell one’s labor in order to survive, and so seems to be one way (...) of abolishing exploitation at its root. This paper will develop a conception of exploitation that resolves the conflict in favor of basic income. The conception of exploitation is grounded in a liberal egalitarian conception of justice rather than in Marx’s labor theory of value or an exclusive focus on the worker-capitalist relation. This position is not premised on an acceptance of the basic institutions of capitalism, but rather is a standpoint from which to evaluate them. It is not necessary to downsize our ideas of freedom and equality. But it is less obvious than it appeared in classic Marxist formulations that socialism is necessary for social justice. To quote the title of a famous article, there could be a ‘capitalist road to communism’, if a substantial basic income is feasible in a capitalist society. (shrink)

In this paper I argue for worker self-management of the media, particularly the press. I begin with a general argument for self-management of enterprises. Then I consider and respond to objections to my proposal arising from the distinctive character of media, their social and political functions, and their legal status. I argue that not only would self-management not conflict with the function of enabling citizens to be informed and participate equally in social and political life, but it would enable media (...) to better perform their function than when controlled by either government or concentrated commercial corporations. But self-managed media would require some rethinking of the meaning of press freedom. And self-management would itself need to be supplemented with other measures such as rights of access to ensure equality of freedom of expression. (shrink)

The United Nations is the world's most extensive international organization whose primary task is to create a new international security framework, the maintenance of international peace and security. United Nations not only to retain the World Health Organization, International Labour Organization, International Court of Justice and other international cooperation organizations, to promote throughout the world from Euro-centric changes to the global system, but also provides a world political center stage, but it has not succeeded in expectations of its founders to (...) establish the international security framework and the security of each country to obtain a new world order. The end of the Cold War can finally restore the UN's ability to successfully perform the duties assigned to it by the Charter, or whether the disappearance of confrontation between the superpowers but exposed the establishment of a global structure of international security barrier deep, although it seems after the were more likely, but will wait and see. The United Nations is the most general international organization in the world at present, the primary mission of which is to establish a new international security framework in order to maintain international peace and security. The UN not only preserved international cooperation organs like the World Health Organization , the International Labour Organization, and the International Court of Justice, and facilitated the transformation of the world from a Eurocentric to a global system; but also provided a focus for world politics. But it has not succeeded in creating an international security framework conceived by its fathers and a new world order from which every state gains a security shield. It remains to be seen whether the end of the Cold War will eventually restore the capacity of the UN to fulfil the role set in its Charter; or whether, as scents more likely, the disappearance of superpower confrontation will only reveal deeper systematic obstacles of the creation of an effective global structure of international security. (shrink)

In this paper it is argued that the predominant mode of organization of work in capitalist society undermines the conditions for self-respect and self-esteem. Although no society can guarantee that everyone have self-respect and self-esteem, it is a requirement of justice that a society provide conditions favorable to their development. Worker control is a form of society which can satisfy this requirement, in a manner that is compatible with political democracy and basic liberties, and thus, from the standpoint of justice, (...) is to be preferred to capitalism. (shrink)

In this paper it is argued that the predominant mode of organization of work in capitalist society undermines the conditions for self-respect and self-esteem. Although no society can guarantee that everyone have self-respect and self-esteem, it is a requirement of justice that a society provide conditions favorable to their development. Worker control is a form of society which can satisfy this requirement, in a manner that is compatible with political democracy and basic liberties, and thus, from the standpoint of justice, (...) is to be preferred to capitalism. (shrink)