estimated surrogates for biodiversity. Using data setsfrom Quebec and Queensland, zve applied four methods to assess the extent to zvhich environmental surrogates can represent biodiversity components: (1) surrogacy graphs; (2) marginal representation plots; (3) Hamming distance function; and (4) Syj rala statistical test for..
The evolutionary study of the mind in the twentieth century has been marked by three self-conscious movements: classical ethology, sociobiology and Evolutionary Psychology (capitalized to indicate that it functions here as a proper name). Classical ethology was established in the years immediately before the Second World War, primarily by Konrad Lorenz and Niko Tinbergen (Burckhardt, 1983). Interrupted by the war, the movement blossomed in the early 1950s, when ethologists established major research institutes in most developed countries and developed a successful (...) sideline in popular science writing. From the outset, ethology sought to apply its methods for the comparative study of animal behavior to human beings, something that was especially prominent in more popular works. Lorenz’s On Aggression (1966a) is perhaps the best known of these works, but several other leading ethologists wrote advocating the application of the new evolutionary science of the mind to problems of international conflict and social unrest. (shrink)
Explicit, quantitative procedures for identifying biodiversity priority areas are replacing the often ad hoc procedures used in the past to design networks of reserves to conserve biodiversity. This change facilitates more informed choices by policy makers, and thereby makes possible greater satisfaction of conservation goals with increased efficiency. A key feature of these procedures is the use of the principle of complementarity, which ensures that areas chosen for inclusion in a reserve network complement those already selected. This paper sketches the (...) historical development of the principle of complementarity and its applications in practical policy decisions. In the first section a brief account is given of the circumstances out of which concerns for more explicit systematic methods for the assessment of the conservation value of different areas arose. The second section details the emergence of the principle of complementarity in four independent contexts. The third section consists of case studies of the use of the principle of complementarity to make practical policy decisions in Australasia, Africa, and America. In the last section, an assessment is made of the extent to which the principle of complementarity transformed the practice of conservation biology by introducing new standards of rigor and explicitness. (shrink)
Philosophers are drawn to the Atomic Theory like a dog to an old shoe, but my results about realism and anti-realism in Tracking Truth, and the distinctive position I have carved out on their basis, are independent of the fate of my comments about that historical case. I will defend those comments against Stanford’s objections below, but first I will explain the argument of my chapter, because its results undermine not only historically important antirealist positions, but also the approach via (...) unconceived conceivables that Stanford’s criticisms (and his pessimistic induction) depend on. The issue is claims about equal evidential support that empiricist defenses of epistemological anti-realism, including Stanford’s, must and do appeal to. In Chapter 6 of Tracking Truth, I show that the best known probabilistic definitions of evidential support imply the anti-realist’s key equalsupport claims are either false or inconsistent with the view he wants to base on them. There are reasons to think that it is not even possible to define a probabilistic notion of support that will do the job the anti-realist needs. It follows from this, as I explain below, that the anti-realist has not defended the claim that we are in principle, or even probably, unable to confirm high-level theories – for this, I say, we must wait and see, and make our best estimates. This, and my claim that we have actually gotten beyond observables – a point made with pregnancy tests and tests for medical conditions – make room for realism. I do not endorse the kind of realist claim that says we generally have a right to believe our successful hypotheses that go beyond observables. Some successful hypotheses are better confirmed than others, and some are not at all. However, since the anti-realist’s general skeptical arguments fail, I also do not think we need such general claims in order to have a right to confidence in those particular hypotheses for which we do have good evidence. I call my approach to the epistemological realism-anti-realism debate “evidential.” The nub of the issue between the two camps has always been whether we have a right to believe our scientific theories – in some sense that includes at least some of their claims about unobservable matters – on the basis of our evidence.1 Answers to this question depend on what our evidence actually is, and on the definition or criteria for evidential support.. (shrink)
Intelligent Design creationism is often criticized for failing to be science because it falls afoul of some demarcation criterion between science and non-science. This paper argues that this objection to Intelligent Design is misplaced because it assumes that a consistent non-theological characterization of Intelligent Design is possible. In contrast, it argues that, if Intelligent Design is taken to be non-theological doctrine, it is not intelligible. Consequently, a demarcation criterion cannot be used to judge its status. This position has the added (...) advantage of providing reasons to reject Intelligent Design creationism without invoking potentially philosophically controversial demarcation criteria. (shrink)
Flights of fancy Content Type Journal Article Pages 1-2 DOI 10.1007/s11016-011-9572-y Authors Sahotra Sarkar, Section of Integrative Biology, Department of Philosophy, University of Texas at Austin, Waggener Hall 316, Austin, TX 78712-1180, USA Journal Metascience Online ISSN 1467-9981 Print ISSN 0815-0796.
This response to Sober's (2008) Evidence and Evolution draws out and criticizes some consequences of his analysis because of its reliance on a likelihood framework for adjucating the dispute between (Intelligent Design) creationism and evolution. In particular, Sober's analysis does not allow it to be formally claimed that evolutionary theory better explains living phenomena than Intelligent Design and makes irrelevant the contribution of the theory of evolution by natural selection to assessments of the status of the argument from design. Finally, (...) a rudimentary alternative framework for theory confirmation is presented here which avoids these conclusions by rejecting likelihoodism and deploying multiple criteria to the problem of scientific theory choice. (shrink)
On the basis of distinctions between those properties of entities that can be defined without reference to other entities and those that (in different ways) cannot, this note argues that non-trivial forms of frequency-dependent selection of entities should be interpreted as selection occurring at a level higher than that of those entities. It points out that, except in degenerately simple cases, evolutionary game-theoretic models of selection are not models of individual selection. Similarly, models of genotypic selection such as heterosis cannot (...) be legitimately interpreted as models of genic selection. The analysis presented here supports the views that: (i) selection should be viewed as a multi-level process; (ii) upper-level selection is ubiquitous; (iii) kin selection should be viewed as a type of group selection rather than individual selection; and (iv) inclusive fitness is not an individual property. (shrink)
Comprised of essays by top scholars in the field, this volume offers concise overviews of philosophical issues raised by biology. Brings together a team of eminent scholars to explore the philosophical issues raised by biology Addresses traditional and emerging topics, spanning molecular biology and genetics, evolution, developmental biology, immunology, ecology, mind and behaviour, neuroscience, and experimentation Begins with a thorough introduction to the field Goes beyond previous treatments that focused only on evolution to give equal attention to other areas, such (...) as molecular and developmental biology Represents both an authoritative guide to philosophy of biology, and an accessible reference work for anyone seeking to learn about this rapidly-changing field. (shrink)
Ricotta argues against the existence of a unique measure of biodiversity by pointing out that no known measure of α-diversity satisfies all the adequacy conditions that have traditionally been set for it. While that technical claim is correct, it is not relevant in the context of defining biodiversity which is most usefully measured by β-diversity. The concept of complementarity provides a closely related family of measures of biodiversity which can be used for systematic conservation planning. Moreover, these measures cannot be (...) replaced by summary statistics but must rely on inventories of biodiversity surrogates at candidate sites for conservation. (shrink)
The philosophy of science is the branch of philosophy that examines the profound philosophical questions that arise from scientific research and theories. A sub-discipline of philosophy that emerged in the twentieth century, the philosophy of science is largely a product of the British and Austrian schools of thought and traditions. The first in-depth reference in the field that combines scientific knowledge with philosophical inquiry, The Philosophy of Science: An Encyclopedia is a two-volume set that brings together an international team of (...) leading scholars to provide over 130 entries on the essential concepts in the philosophy of science. The areas covered include biology, chemistry, epistemology and metaphysics, physics, psychology and mind, the social sciences, and key figures in the combined studies of science and philosophy. Essays range in length from 3,000 to 7,500 words and represent the most up-to-date philosophical thinking on timeless scientific topics such as determinism, explanation, laws of nature, perception, individuality, time, and economics as well as timely topics like adaptation, conservation biology, quantum logic, consciousness, evolutionary psychology, and game theory. Offering thorough explorations and destined to become the most authoritative presentation of the field available, this Encyclopedia is a unique and groundbreaking guide to this fascinating field. (shrink)
This book explores the epistemological and ethical issues at the foundations of environmental philosophy, emphasizing the conservation of biodiversity. Sahota Sarkar criticizes previous attempts to attribute intrinsic value to nature and defends an anthropocentric position on biodiversity conservation based on an untraditional concept of transformative value. Unlike other studies in the field of environmental philosophy, this book is as much concerned with epistemological issues as with environmental ethics. It covers a broad range of topics, including problems of explanation and prediction (...) in traditional ecology and how individual-based models and Geographic Information Systems (GIS) technology is transforming ecology. Introducing a brief history of conservation biology, Sarkar analyzes the new consensus framework for conservation planning through adaptive management. He concludes with a discussion of the future directions for theoretical research in conservation biology and environmental philosophy. (shrink)
Maynard Smith’s defenses of adaptationism and of the value of optimization theory in evolutionary biology are both criticized. His defense does not adequately respond to the criticism of adaptationism by Gould and Lewontin. It is also argued here that natural selection cannot be interpreted as an optimization process if the objective function to be optimized is either (i) interpretable as a fitness, or (ii) correlated with the mean population fitness. This result holds even if fitnesses are frequency-independent; the problem is (...) further exacerbated in the frequency-dependent context modeled by evolutionary game theory. However, Eshel and Feldman’s new results on “long-term” evolution may provide some hope for the continuing relevance of the game-theoretic framework. These arguments also demonstrate the irrelevance of attempts by Intelligent Design creationists to use computational limits on optimization algorithms as evidence against evolutionary theory. It is pointed out that adaptation, natural selection, and optimization are not equivalent processes in the context of biological evolution. (shrink)
This paper analyzes the development of evolutionary theory in the period from 1918 to 1932. It argues that: (i) Fisher's work in 1918 constituted a not fully satisfactory reduction of biometry to Mendelism; (ii) there was a synthesis in the 1920s but that this synthesis was mainly one of classical genetics with population genetics, with Haldane's The Causes of Evolution being its founding document; (iii) the most important achievement of the models of theoretical population genetics was to show that natural (...) selection sufficed as a mechanism for evolution; and (iv) Haldane formulated a prospective evolutionary theory in the 1920s whereas Fisher and Wright formulated retrospective theories of evolutionary history. (shrink)
This paper analyzes the development of evolutionary theory in the period from 1918 to 1932. It argues that: (i) Fisher’s work in 1918 constitutes a not fully satisfactory reduction of biometry to Mendelism; (ii) that there was a synthesis in the 1920s but that this synthesis was mainly one of classical genetics with population genetics, with Haldane’s Causes of Evolution being its founding document; (iii) the most important achievement of the models of theoretical population genetics was to show that natural (...) selection sufficed as a mechanism for evolution; (iv) Haldane formulated a prospective evolutionary theory in the 1920s whereas Fisher and Wright formulated retrospective theories of evolutionary history; and (v) in the context of the history of evolutionary biology, the differences between Fisher, Haldane, and Wright are as important as their similarities. (shrink)
A framework is presented in which the role ofdevelopmental rules in phenotypic evolution canbe studied for some simple situations. Usingtwo different implicit models of development,characterized by different developmental mapsfrom genotypes to phenotypes, it is shown bysimulation that developmental rules and driftcan result in directional phenotypic evolutionwithout selection. For both models thesimulations show that the critical parameterthat drives the final phenotypic distributionis the cardinality of the set of genotypes thatmap to each phenotype. Details of thedevelopmental map do not matter. If phenotypesare (...) randomly assigned to genotypes, the lastresult can also be proved analytically. (shrink)
The scope and nature of reductionist explanation in quantum physics is analyzed, with special attention being paid to the situation in quantum physics.
Habitat dioramas depicting ecological relations between organisms and their natural environments have become the preferred mode of museum display in most natural history museums in North America and Europe. Dioramas emerged in the late nineteenth century as an alternative mode of museum installation from taxonomically arranged cases. We suggest that this change was closely connected to the emergence of a biogeographical framework rooted in evolutionary theory and positing the existence of distinct biogeographical zones. We tie the history of dioramas to (...) earlier visual resources such as the thematic images that Wallace introduced to illustrate his 1876 Geographical Distribution of Animals. These images were unique in their time because each of them simultaneously depicted animals from several different taxa, rather than only one, as well as the ecological relations between animals and their habitats. Both, visually and with respect to their function within biogeography, these images presaged the habitat dioramas that came shortly afterwards. Not coincidentally, Wallace explicitly advocated the use of dioramas for museum display in ongoing debates on museum reform. Wallace's suggestions were put into practice by committed evolutionists such as Gottlieb von Koch who pioneered the diorama installation in the Grand Ducal Museum in Darmstadt (Germany) in 1906. As in Wallace's illustrations, Koch's dioramas were designed to respresent biogeographical zones. This paper explores the function of these visual displays of biogeographical relations. It argues that, in both the scientific and public realms, biogeogaphical zones were defined and constructed by visual means; recourse to visual representation was more than a method of communication. (shrink)
A standard norm of reaction (NoR) is a graphical depiction of the phenotypic value of some trait of an individual genotype in a population as a function of an environmental parameter. NoRs thus depict the phenotypic plasticity of a trait. The topological properties of NoRs for sets of different genotypes can be used to infer the presence of (non-linear) genotype-environment interactions. While it is clear that many NoRs are adaptive, it is not yet settled whether their evolutionary etiology should be (...) explained by selection on the mean phenotypic trait values in different environments or whether there are specific genes conferring plasticity. If the second alternative is true the NoR is itself an object of selection. Generalized NoRs depict plasticity at the level of populations or subspecies within a species, species within a genus, or taxa at higher levels. Historically, generalized NoRs have routinely been drawn though rarely explicitly recognized as such. Such generalized NoRs can be used to make evolutionary inferences at higher taxonomic levels in a way analagous to how standard NoRs are used for microevolutionary inferences. (shrink)
David Malament's (1977) well-known result, which is often taken to show the uniqueness of the Poincare-Einstein convention for defining simultaneity, involves an unwarranted physical assumption: that any simultaneity relation must remain invariant under temporal reflections. Once that assumption is removed, his other criteria for defining simultaneity are also satisfied by membership in the same backward (forward) null cone of the family of such cones with vertices on an inertial path. What is then unique about the Poincare-Einstein convention is that it (...) is independent of the choice of inertial path in a given inertial frame, confirming a remark in Einstein 1905. Similarly, what is unique about the backward (forward) null cone definition is that it is independent of the state of motion of an observer at a point on the inertial path. (shrink)
A new direction in philosophy Between 1920 and 1940 logical empiricism reset the direction of philosophy of science and much of the rest of Anglo-American philosophy. It began as a relatively organized movement centered on the Vienna Circle, and like-minded philosophers elsewhere, especially in Berlin. As Europe drifted into the Nazi era, several important figures, especially Carnap and Neurath, also found common ground in their liberal politics and radical social agenda. Together, the logical empiricists set out to reform traditional philosophy (...) with a new set of doctrines more firmly grounded in logic and science. Criticism and decline Because of Nazi persecution, most of the European adherents of logical empiricism moved to the United States in the late 1930s. During the 1940s, many of their most cherished tenets became targets of criticism from outsiders as well as from within their own ranks. Philosophers of science in the late 1950s and 1960s rejected logical empiricism and, starting in the 1970s, presented such alternative programs such as scientific realism with evolutionary epistemology. A resurgence of interest During the early 1980s, philosophers and historians of philosophy began to study logical empiricism as an important movement. Unlike their predecessors in the 1960s-for whom the debate over logical empiricism now seems to have been largely motivated by professional politics-these philosopher no longer have to take positions for or against logical empiricism. The result has been a more balanced view of that movement, its achievements, its failures, and its influence. Hard-to-find core writings now available This collection makes available a selection of the most influential and representative writings of the logical empiricists, important contemporary criticisms of their doctrines, their responses, as well as the recent reappraisals. Introductions to each volume examine the articles in historical context and provide importantbackground information that is vital to a full understanding of the issues discussed. They outline prevalent trends, identifying leading figures and summarize their positions and reasoning, as well as those of opposing thinkers. (shrink)
A new direction in philosophy Between 1920 and 1940 logical empiricism reset the direction of philosophy of science and much of the rest of Anglo-American philosophy. It began as a relatively organized movement centered on the Vienna Circle, and like-minded philosophers elsewhere, especially in Berlin. As Europe drifted into the Nazi era, several important figures, especially Carnap and Neurath, also found common ground in their liberal politics and radical social agenda. Together, the logical empiricists set out to reform traditional philosophy (...) with a new set of doctrines more firmly grounded in logic and science. Criticism and decline Because of Nazi persecution, most of the European adherents of logical empiricism moved to the United States in the late 1930s. During the 1940s, many of their most cherished tenets became targets of criticism from outsiders as well as from within their own ranks. Philosophers of science in the late 1950s and 1960s rejected logical empiricism and, starting in the 1970s, presented such alternative programs such as scientific realism with evolutionary epistemology. A resurgence of interest During the early 1980s, philosophers and historians of philosophy began to study logical empiricism as an important movement. Unlike their predecessors in the 1960s-for whom the debate over logical empiricism now seems to have been largely motivated by professional politics-these philosopher no longer have to take positions for or against logical empiricism. The result has been a more balanced view of that movement, its achievements, its failures, and its influence. Hard-to-find core writings now available This collection makes available a selection of the most influential and representative writings of the logical empiricists, important contemporary criticisms of their doctrines, their responses, as well as the recent reappraisals. Introductions to each volume examine the articles in historical context and provide importantbackground information that is vital to a full understanding of the issues discussed. They outline prevalent trends, identifying leading figures and summarize their positions and reasoning, as well as those of opposing thinkers. (shrink)
A new direction in philosophy Between 1920 and 1940 logical empiricism reset the direction of philosophy of science and much of the rest of Anglo-American philosophy. It began as a relatively organized movement centered on the Vienna Circle, and like-minded philosophers elsewhere, especially in Berlin. As Europe drifted into the Nazi era, several important figures, especially Carnap and Neurath, also found common ground in their liberal politics and radical social agenda. Together, the logical empiricists set out to reform traditional philosophy (...) with a new set of doctrines more firmly grounded in logic and science. Criticism and decline Because of Nazi persecution, most of the European adherents of logical empiricism moved to the United States in the late 1930s. During the 1940s, many of their most cherished tenets became targets of criticism from outsiders as well as from within their own ranks. Philosophers of science in the late 1950s and 1960s rejected logical empiricism and, starting in the 1970s, presented such alternative programs such as scientific realism with evolutionary epistemology. A resurgence of interest During the early 1980s, philosophers and historians of philosophy began to study logical empiricism as an important movement. Unlike their predecessors in the 1960s-for whom the debate over logical empiricism now seems to have been largely motivated by professional politics-these philosopher no longer have to take positions for or against logical empiricism. The result has been a more balanced view of that movement, its achievements, its failures, and its influence. Hard-to-find core writings now available This collection makes available a selection of the most influential and representative writings of the logical empiricists, important contemporary criticisms of their doctrines, their responses, as well as the recent reappraisals. Introductions to each volume examine the articles in historical context and provide importantbackground information that is vital to a full understanding of the issues discussed. They outline prevalent trends, identifying leading figures and summarize their positions and reasoning, as well as those of opposing thinkers. (shrink)
A new direction in philosophy Between 1920 and 1940 logical empiricism reset the direction of philosophy of science and much of the rest of Anglo-American philosophy. It began as a relatively organized movement centered on the Vienna Circle, and like-minded philosophers elsewhere, especially in Berlin. As Europe drifted into the Nazi era, several important figures, especially Carnap and Neurath, also found common ground in their liberal politics and radical social agenda. Together, the logical empiricists set out to reform traditional philosophy (...) with a new set of doctrines more firmly grounded in logic and science. Criticism and decline Because of Nazi persecution, most of the European adherents of logical empiricism moved to the United States in the late 1930s. During the 1940s, many of their most cherished tenets became targets of criticism from outsiders as well as from within their own ranks. Philosophers of science in the late 1950s and 1960s rejected logical empiricism and, starting in the 1970s, presented such alternative programs such as scientific realism with evolutionary epistemology. A resurgence of interest During the early 1980s, philosophers and historians of philosophy began to study logical empiricism as an important movement. Unlike their predecessors in the 1960s-for whom the debate over logical empiricism now seems to have been largely motivated by professional politics-these philosopher no longer have to take positions for or against logical empiricism. The result has been a more balanced view of that movement, its achievements, its failures, and its influence. Hard-to-find core writings now available This collection makes available a selection of the most influential and representative writings of the logical empiricists, important contemporary criticisms of their doctrines, their responses, as well as the recent reappraisals. Introductions to each volume examine the articles in historical context and provide importantbackground information that is vital to a full understanding of the issues discussed. They outline prevalent trends, identifying leading figures and summarize their positions and reasoning, as well as those of opposing thinkers. (shrink)
A new direction in philosophy Between 1920 and 1940 logical empiricism reset the direction of philosophy of science and much of the rest of Anglo-American philosophy. It began as a relatively organized movement centered on the Vienna Circle, and like-minded philosophers elsewhere, especially in Berlin. As Europe drifted into the Nazi era, several important figures, especially Carnap and Neurath, also found common ground in their liberal politics and radical social agenda. Together, the logical empiricists set out to reform traditional philosophy (...) with a new set of doctrines more firmly grounded in logic and science. Criticism and decline Because of Nazi persecution, most of the European adherents of logical empiricism moved to the United States in the late 1930s. During the 1940s, many of their most cherished tenets became targets of criticism from outsiders as well as from within their own ranks. Philosophers of science in the late 1950s and 1960s rejected logical empiricism and, starting in the 1970s, presented such alternative programs such as scientific realism with evolutionary epistemology. A resurgence of interest During the early 1980s, philosophers and historians of philosophy began to study logical empiricism as an important movement. Unlike their predecessors in the 1960s-for whom the debate over logical empiricism now seems to have been largely motivated by professional politics-these philosopher no longer have to take positions for or against logical empiricism. The result has been a more balanced view of that movement, its achievements, its failures, and its influence. Hard-to-find core writings now available This collection makes available a selection of the most influential and representative writings of the logical empiricists, important contemporary criticisms of their doctrines, their responses, as well as the recent reappraisals. Introductions to each volume examine the articles in historical context and provide importantbackground information that is vital to a full understanding of the issues discussed. They outline prevalent trends, identifying leading figures and summarize their positions and reasoning, as well as those of opposing thinkers. Available individually by volume. 1. The Emergence of Logical Empiricism (0-8153-2262-3) 432 pages 2. Logical Empiricism at its Peak (0-8153-2263-1) 4243 pages 3. Logic, Probability, and Epistemology (0-8153-2264-X) 424 pages 4. Logical Empiricism and the Special Sciences (0-8153-2265-8) 376 pages 5. Decline and Obsolescence of Logical Empiricsm (0-8153-2266-6) 440 pages 6. The Legacy of the Vienna Circle (0-8153-2267-4) 400 pages. (shrink)
A new direction in philosophy Between 1920 and 1940 logical empiricism reset the direction of philosophy of science and much of the rest of Anglo-American philosophy. It began as a relatively organized movement centered on the Vienna Circle, and like-minded philosophers elsewhere, especially in Berlin. As Europe drifted into the Nazi era, several important figures, especially Carnap and Neurath, also found common ground in their liberal politics and radical social agenda. Together, the logical empiricists set out to reform traditional philosophy (...) with a new set of doctrines more firmly grounded in logic and science. Criticism and decline Because of Nazi persecution, most of the European adherents of logical empiricism moved to the United States in the late 1930s. During the 1940s, many of their most cherished tenets became targets of criticism from outsiders as well as from within their own ranks. Philosophers of science in the late 1950s and 1960s rejected logical empiricism and, starting in the 1970s, presented such alternative programs such as scientific realism with evolutionary epistemology. A resurgence of interest During the early 1980s, philosophers and historians of philosophy began to study logical empiricism as an important movement. Unlike their predecessors in the 1960s-for whom the debate over logical empiricism now seems to have been largely motivated by professional politics-these philosopher no longer have to take positions for or against logical empiricism. The result has been a more balanced view of that movement, its achievements, its failures, and its influence. Hard-to-find core writings now available This collection makes available a selection of the most influential and representative writings of the logical empiricists, important contemporary criticisms of their doctrines, their responses, as well as the recent reappraisals. Introductions to each volume examine the articles in historical context and provide importantbackground information that is vital to a full understanding of the issues discussed. They outline prevalent trends, identifying leading figures and summarize their positions and reasoning, as well as those of opposing thinkers. (shrink)
It is shown that, for technical reasons, the additivity of variance criterion employed by Lloyd (1988) to define a unit of selection is, in almost all models of selection, inconsistent with the possibility that genes are sometimes not the unit of selection. A case when the latter view is particularly attractive is that of heterosis, and the additivity criterion is inadequate in even such an extreme case. The connection between that criterion and the so-called "fundamental theorem of natural selection" is (...) briefly explored. Skepticism is expressed about the value of measures such as variance in efforts to resolve any of the disputes about the "units of selection.". (shrink)
A classification of models of reduction into three categories — theory reductionism, explanatory reductionism, and constitutive reductionism — is presented. It is shown that this classification helps clarify the relations between various explications of reduction that have been offered in the past, especially if a distinction is maintained between the various epistemological and ontological issues that arise. A relatively new model of explanatory reduction, one that emphasizes that reduction is the explanation of a whole in terms of its parts is (...) also presented in detail. Finally, the classification is used to clarify the debate over reductionism in molecular biology. It is argued there that while no model from the category of theory reduction might be applicable in that case, models of explanatory reduction might yet capture the structure of the relevant explanations. (shrink)
This paper analyzes the interaction between science, philosophy and politics (including ideology) in the early work of J. B. S. Haldane (from 1922 to 1937). This period is particularly important, not only because it is the period of Haldane's most significant biological work (both in biochemistry and genetics), but also because it is during this period that his philosophical and political views underwent their most significant transformation. His philosophical stance first changed from a radical organicism to a position far more (...) compatible with mechanical materialism. The primary intellectual influence that was responsible for this shift was that of F. G. Hopkins. Later, Haldane came to accept Marxism and its official metaphysics, dialectical materialism, a move that let him accept the materialist conception of the world while still maintaining a resolute distance from mechanism. Throughout all these changes, what is most obvious is the influence of science on Haldane's philosophical views. An influence in the opposite direction is far less apparent. (shrink)
Mendel's work in hybridization is ipso facto a study in inheritance. He is explicit in his interest to formulate universal generalizations, and at least in the case of the independent segregation of traits, he formulated his conclusions in the form of a law. Mendel did not discern, however, the inheritance of traits from that of the potential for traits. Choosing to study discrete non-overlapping traits, this did not hamper his efforts.
It is shown that complex adaptations are best modelled as discrete processes represented on directed weighted graphs. Such a representation captures the idea that problems of adaptation in evolutionary biology are problems in a discrete space, something that the conventional representations using continuous adaptive landscapes does not. Further, this representation allows the utilization of well-known algorithms for the computation of several biologically interesting results such as the accessibility of one allele from another by a specified number of point mutations, the (...) accessibility of alleles at a local maximum of fitness, the accessibility of the allele with the globally maximum fitness, etc. A reduction of a model due to Kauffman and Levin to such a representation is explicitly carried out and it is shown how this reduction clarifies the biological questions that are of interest. (shrink)
The ongoing controversy about the possibility of directed mutations in bacteria is examined for its methodological, and thereby philosophical, implications. The method of fluctuation analysis, widely used to investigate whether mutations are random or directed, is described and subjected to a conceptual critique which shows that it cannot decide whether some mutations are directed while most are random. In this context, recent experiments that exploit this possibility to suggest that directed mutations occur in bacteria are described. Interpretive and experimental responses (...) to such claims are briefly analyzed. Finally it is argued that mere statistical analysis, such as fluctuation analysis, cannot resolve this dispute. What will probably be required is an investigation of mechanisms of mutagenesis, an investigation that is intrinsically reductive. (shrink)
Two aspects of the Eigen theory of the origin of life are separated: (i) a theory of evolution at the molecular level, and (ii) the special dynamical properties of hypercycles when that theory is applied to them. It is shown that the former can be applied to a variety of molecular systems which then satisfy Lewontin's criteria for evolution by natural selection. This insight is used to show how, at the molecular level, this theory of natural selection can be used (...) to provide physical warrants for functional explanations. The position of hypercycles in this picture and the reasons for their suitability as a model for the origin of life are also discussed. (shrink)
