The focus of this study was to analyze the content, distribution, and comparative genome relationships of 996 chromosome bin-mapped expressed sequence tags accounting for 2266 restriction fragments on the homoeologous group 3 chromosomes of hexaploid wheat. Of these loci, 634, 884, and 748 were mapped on chromosomes 3A, 3B, and 3D, respectively. The individual chromosome bin maps revealed bins with a high density of mapped ESTs in the distal region and bins of low density in the proximal region of the (...) chromosome arms, with the exception of 3DS and 3DL. These distributions were more localized on the higher-resolution group 3 consensus map with intermediate regions of high-mapped-EST density on both chromosome arms. Gene ontology classification of mapped ESTs was not significantly different for homoeologous group 3 chromosomes compared to the other groups. A combined analysis of the individual bin maps using 537 of the mapped ESTs revealed rearrangements between the group 3 chromosomes. Approximately 232 of the consensus mapped ESTs matched sequences on rice chromosome 1 and revealed large- and small-scale differences in gene order. Of the group 3 mapped EST unigenes ∼21 and 32% matched the Arabidopsis coding regions and proteins, respectively, but no chromosome-level gene order conservation was detected. (shrink)

The complex hexaploid wheat genome offers many challenges for genomics research. Expressed sequence tags facilitate the analysis of gene-coding regions and provide a rich source of molecular markers for mapping and comparison with model organisms. The objectives of this study were to construct a high-density EST chromosome bin map of wheat homoeologous group 2 chromosomes to determine the distribution of ESTs, construct a consensus map of group 2 ESTs, investigate synteny, examine patterns of duplication, and assess the colinearity with rice (...) of ESTs assigned to the group 2 consensus bin map. A total of 2600 loci generated from 1110 ESTs were mapped to group 2 chromosomes by Southern hybridization onto wheat aneuploid chromosome and deletion stocks. A consensus map was constructed of 552 ESTs mapping to more than one group 2 chromosome. Regions of high gene density in distal bins and low gene density in proximal bins were found. Two interstitial gene-rich islands flanked by relatively gene-poor regions on both the short and long arms and having good synteny with rice were discovered. The map locations of two ESTs indicated the possible presence of a small pericentric inversion on chromosome 2B. Wheat chromosome group 2 was shown to share syntenous blocks with rice chromosomes 4 and 7. (shrink)

This report describes the rationale, approaches, organization, and resource development leading to a large-scale deletion bin map of the hexaploid wheat genome. Accompanying reports in this issue detail results from chromosome bin-mapping of expressed sequence tags representing genes onto the seven homoeologous chromosome groups and a global analysis of the entire mapped wheat EST data set. Among the resources developed were the first extensive public wheat EST collection. Described are protocols for sequencing, sequence processing, EST nomenclature, and the assembly of (...) ESTs into contigs. These contigs plus singletons were used for selection of distinct sequence motif unigenes. Selected ESTs were rearrayed, validated by 5′ and 3′ sequencing, and amplified for probing a series of wheat aneuploid and deletion stocks. Images and data for all Southern hybridizations were deposited in databases and were used by the coordinators for each of the seven homoeologous chromosome groups to validate the mapping results. Results from this project have established the foundation for future developments in wheat genomics. (shrink)

Deep neural networks (DNNs) have had extraordinary successes in classifying photographic images of objects and are often described as the best models of biological vision. This conclusion is largely based on three sets of findings: (1) DNNs are more accurate than any other model in classifying images taken from various datasets, (2) DNNs do the best job in predicting the pattern of human errors in classifying objects taken from various behavioral datasets, and (3) DNNs do the best job in predicting (...) brain signals in response to images taken from various brain datasets (e.g., single cell responses or fMRI data). However, these behavioral and brain datasets do not test hypotheses regarding what features are contributing to good predictions and we show that the predictions may be mediated by DNNs that share little overlap with biological vision. More problematically, we show that DNNs account for almost no results from psychological research. This contradicts the common claim that DNNs are good, let alone the best, models of human object recognition. We argue that theorists interested in developing biologically plausible models of human vision need to direct their attention to explaining psychological findings. More generally, theorists need to build models that explain the results of experiments that manipulate independent variables designed to test hypotheses rather than compete on making the best predictions. We conclude by briefly summarizing various promising modeling approaches that focus on psychological data. (shrink)

On several key issues we agree with the commentators. Perhaps most importantly, everyone seems to agree that psychology has an important role to play in building better models of human vision, and (most) everyone agrees (including us) that deep neural networks (DNNs) will play an important role in modelling human vision going forward. But there are also disagreements about what models are for, how DNN–human correspondences should be evaluated, the value of alternative modelling approaches, and impact of marketing hype in (...) the literature. In our view, these latter issues are contributing to many unjustified claims regarding DNN–human correspondences in vision and other domains of cognition. We explore all these issues in this response. (shrink)

The consistency strength of the ∑2 priority method is I∑2, yet classical theorems proven by this method have been proved from I∑1. Is there a statement about the structure of the r.e. degrees that can be proved using a ∑2 argument and cannot be proved from I∑1?We rule out statements in the language of partial orderings of the form …[], where is quantifier-free, by showing that the following can be proved in I∑1.If P is any recursive partial ordering with a (...) maximal point d, and a is any nonrecursive incomplete r.e. degree, then P can be embedded into the r.e. degrees by an embedding sending d to a. (shrink)

A ceux qui se montrent désireux de saisir l'épaisseur politique et historique du droit constitutionnel, les différends opposant les corps constitués peuvent apparaître, dans leurs expressions les plus marquées, comme des objets d'étude particulièrement stimulants. En effet, ces conflits peuvent se présenter comme de singuliers laboratoires où devient brusquement visible la texture politique des lois constitutionnelles dont les dispositions sont parfois si fortement tissées d'incertitudes et d'ellipses qu'elles laissent soudain jaillir l'imprévisible. D'une part, le conflit constitutionnel n'est pas une simple (...) controverse constitutionnelle participant généralement d'un processus historique de pacification des différends politiques par le droit : d'autre part, il constitue un conflit politique dont la particularité réside dans le fait que les acteurs s'efforcent d'étayer leur raisonnement par des arguments juridiques tirés d'une lecture de la lettre constitutionnelle, chaque camp accusant la partie adverse d'une mésinterprétation ou d'une violation de ses dispositions. Lors d'une telle crise, mis à l'épreuve de sa propre force, le droit constitutionnel prend toute la mesure de l'indétermination et de la duplicité de ses règles. Qu'ils portent sur l'interprétation ou sur l'application des dispositions constitutionnelles relatives aux modalités d'exercice de la puissance étatique, les différends entre organes constitués peuvent ainsi, dans certaines circonstances, dépasser le stade de la simple controverse pour épouser la forme plus dense du conflit constitutionnel. En effet, quand la difficulté de mettre un terme au différend est telle que les processus de discussion et de délibération codifiés par le droit sont eux-mêmes impuissants à imposer une solution reconnue acceptable par tous les acteurs, le durcissement de la crise peut alors conduire à une situation qu'il est possible de qualifier de conflit constitutionnel. Le présent ouvrage recueille les Actes de la Journée d'études organisée à la Faculté de droit et de science politique de Rennes, le 28 novembre 2008, par le Laboratoire d'Etude du Droit Public de l'université de Rennes 1. (shrink)

Structuré en trois grandes parties, Vieillesses et vieillissements dresse un vaste panorama des recherches contemporaines francophones en la matière. L’ouvrage est constitué en trois parties : une première relative à la construction politique des problèmes de la vieillesse, une seconde attentive aux cadres sociaux de la vieillesse et une troisième centrée sur l’expérience du vieillissement. Les éditeurs ont fait le choix judicieux de faire dialoguer une trentaine d’auteurs, alternant articles..

The field of AI safety aims to prevent increasingly capable artificially intelligent systems from causing humans harm. Research on moral alignment is widely thought to offer a promising safety strategy: if we can equip AI systems with appropriate ethical rules, according to this line of thought, they'll be unlikely to disempower, destroy or otherwise seriously harm us. Deontological morality looks like a particularly attractive candidate for an alignment target, given its popularity, relative technical tractability and commitment to harm-avoidance principles. I (...) argue that the connection between moral alignment and safe behavior is more tenuous than many have hoped. In general, AI systems can possess either of these properties in the absence of the other, and we should favor safety when the two conflict. In particular, advanced AI systems governed by standard versions of deontology need not be especially safe. (shrink)

Originally published in 1957, the primary aim of this study was to shed light upon the logical character of the psychology of perception. D.W. Hamlyn begins by delimiting the field of psychological inquiry into perception, then gives a detailed account of the types of explanation appropriate in the field. He maintains that these explanations have certain important peculiarities which distinguish them from other scientific inquiries. In view of the central importance of Gestalt Theory in this field an account is given (...) of its origins, and its main features are critically discussed. The work should still be of considerable interest to both philosophers and psychologists, as well as to all those interested in the relations between the two subjects. (shrink)

This paper is a review of the influence that lógos has had on ancient Greek, Jewish, and Christian writings. During the philosophical era known as Middle Platonism, the concept/ontology of the lógos played a unique role in enabling Pagan, Jewish, and Christian intellectuals to communicate on a small space of common ground.

In lieu of an abstract, here is a brief excerpt of the content:Reviewed by:Transcendental Phenomenology as Human Possibility: Husserl and Fink on the Phenomenologizing Subject by Denis DŽANIĆD. J. HobbsDŽANIĆ, Denis. Transcendental Phenomenology as Human Possibility: Husserl and Fink on the Phenomenologizing Subject. Cham: Springer, 2023. x + 236 pp. Cloth, $119.99Denis Džanić’s Transcendental Phenomenology as Human Possibility, despite its superficially historical focus on a specific period of collaboration between Edmund Husserl and his somewhat wayward protégé Eugen Fink, addresses key (...) systematic issues in transcendental phenomenology, namely, how the act of phenomenologizing should be understood in connection with the specific human beings who aim to become phenomenologists, and what the answer to this question tells us about both the genuine subject of phenomenology and the motivation for phenomenologizing. These questions are important for our understanding of not only the historical development of phenomenology but also the practice and goals of phenomenology—specifically, for a conception of phenomenologizing as a project in which we, as particular, historical, empirical figures, might want to engage.Much of the book focuses on laying the groundwork for understanding these complicated issues both historically and systematically. Džanić does an admirable job of tracing the rapidly evolving interactions between Husserl and Fink, both as intellectual collaborators on this philosophical project and as a pair of very human figures who ultimately found themselves pursuing quite different solutions to the problems of the subject and origin of phenomenology. He focuses particularly on the Sixth Cartesian Meditation, Fink’s attempt to extend Husserl’s famous text to include a phenomenology of the act of phenomenologizing itself (including Husserl’s marginal comments on the text), although he draws on a number of other significant texts and manuscripts (mostly Husserl’s, albeit with an extended aside on Heidegger) wherever they are helpful for explicating the complex evolution of Husserl’s thought on the subject. Admittedly, the book thus takes on a challenging task—both because of the difficult nature of this topic and because of the obscurity of the technical terms required to discuss it. However, despite the necessarily enigmatic character of the relevant language, Džanić’s attempts to explore the main outlines of this issue are worthwhile, particularly due to his ability to resist the temptation to view Husserl’s thought here as monolithic.In the early chapters, Džanić explicates in detail the rather complicated solution that Fink proposed to this difficulty, namely, the abandonment (to some extent) of the ultimately human origin of phenomenology in favor of a fundamentally nonhuman (and eventually meontic) conception of the transcendental ego, which generated a great deal of elaborate and (at least in the Sixth Meditation) inadequately supported speculation. For Fink, both the motivation to phenomenologize and the act of phenomenologizing itself ultimately stem from a source that is fundamentally prior to—in a(n onto)logical rather than temporal sense—any empirical ego or empirical act of phenomenologizing, a source that merely “enworlds” itself (in various complicated senses that Džanić does [End Page 145] an admirable job of clarifying) in the apparently anthropologistic, everyday world of individual phenomenologists. Džanić calls this interpretation of phenomenology Fink’s “epistemological anti-humanism,” and it serves as the basis for one potential (radically anti-Heideggerian but nevertheless somewhat disappointing) solution to the question of why we should phenomenologize at all. As Džanić notes, this solution was at least briefly taken up by Fink’s mentor Husserl himself, although the degree to which Husserl actually endorsed this path beyond the level of a fleeting flirtation remains questionable. Ultimately, as Džanić rightly highlights and as becomes abundantly clear in Husserl’s (often rather scathing) notes on Fink’s Sixth Cartesian Meditation, he abandoned this interpretation.Accordingly, in the later chapters of the book, Džanić traces Husserl’s ultimate development of a quite different solution to the problems of the origin and motivation of phenomenology—a solution that, unlike his brief foray into Finkian grandeur, views the act of phenomenologizing as essentially rooted in human possibility (that is, as part of the famous lifeworld that features so prominently in Husserl’s work, especially in the Crisis and other late texts). After his collaboration with and... (shrink)

Funding organizations around the world are adopting open science policies, resulting in a pressing need for open science programs. In response to the 2011 decadal survey, NASA sought to expand and accelerate omics research, releasing its GeneLab Strategic Plan in 2014. GeneLab is an open science data repository and analysis portal for spaceflight and space-relevant omics data. GeneLab’s output has been outstanding, but its full potential as a way to transform space biology has not yet been achieved. NASA should pursue (...) the development of GeneLab as an open science platorm in earnest. (shrink)

Inside What Would Plato Do?, you'll find the basics of philosophy, written in an easy, digestible way we can all understand, along with questions to help you apply these important theories to your own life. So, after you've learned about a philosophical concept, you'll then be challenged to test yourself and see how the results can impact your daily life. For instance, after learning about Kant's theory of morality and the importance of intention you're challenged with questions like: Can good (...) people do bad things? Was there a time when you intended to do something helpful that ended up being hurtful? Does that make you a good person (because you intended to do good) or a bad person (because the results were bad)? What Would Plato Do? will not only help you better understand some of the greatest thinkers ever but will also help you think of the world around you in a whole new way! (shrink)

This paper argues that the concept and role of ‘institutional racism’ in contemporary discussions of race should be reconsidered. It starts by distinguishing between ‘intrinsic institutional racism’, which holds that institutions are racist in virtue of their constitutive features, and ‘extrinsic institutional racism’, which holds that institutions are racist in virtue of their negative effects. It accepts intrinsic institutional racism, but argues that a ‘disparate impact’ conception of extrinsic conception faces a number of objections, the most serious being that it (...) has no plausible account of what it is that makes extrinsically racist institutions racist. It also argues that claims about the explanatory indispensability of institutional racism are overstated (individual racism is at least as important), critiques structural approaches to racial inequality, and suggests that there is reason to doubt whether institutional reform can provide us with all that morality may require in the racial domain. (shrink)

In his 1922/1923 articles for the Japanese magazine _Kaizō_, Edmund Husserl identifies a particular “humanity” or human culture by the purposeful idea [_Zweckidee_] consciously embraced by the community. This purposeful idea is attained through rational self-formation on the part of the community in a manner analogous to the rational self-formation of the individual human being. Thereafter, it can be referenced to distinguish different cultures (or stages of cultural development) from one another through its objective manifestation in communal groups and cultural (...) products, as Husserl retraces in a historical account of the development of Western history. This paper explores the essential character of this conception of the purposeful idea from both an exegetical and a systematic perspective, examining in particular the relationship between such an idea and the values experienced by individual subjects within a culture (which are, according to Husserl, also available at the level of objective culture in relation to a communal subject). The paper argues that Husserl’s basic conception of the purposeful idea is a good model for understanding certain essential characteristics of cultural constitution in general, although some of his fundamental assumptions—especially the strict identity he attempts to establish between a purposeful idea as such and the specific goal of universal, rational self-understanding—turn out to be somewhat more questionable in light of the connection between the purposeful idea and the genuinely felt values underlying it. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:BOOK REVIEWS 741 pointedly, what he is asking for is " the ' planned dissolution ' of the Latin Church into a considerable number of distinct, autonomous ' patriarchates ' " (p. 132). These suggestions, although not original, are intriguing. They deserve, however, more than three pages. What is needed is a detailed presentation of these changes, indicating their historical context, their advantages and disadvantages, and their practical implementation. (...) Despite the criticisms given above, there is much good material to be found in this crisply written book. I agree in general with Hill's judgment that Church authority should embody a collegial rather than a monarchical ecclesiology. He shows that the MC ecclesiology has a solid foundation in scripture and tradition and its cornerstone is the theology of the local Church. Furthermore, he is correct in insisting that the doctrines of collegiality and the priesthood of the faithful are urgent questions in contemporary ecclesiology and that they have broad ecumenical ramifications. He speaks convincingly of greater lay participation, local autonomy, consultation, and accountability. At the same time, his partisanship leads him to caricature the MP view. He will not persuade many MP supporters by criticizing their "highhanded authoritarianism and paternalism " (p. 53) and " ecclesiastical dishonesty " (p. 127) or by claiming that the Roman Curia " is neuro· tically obsessed with the matter of papal authority" (p. 114). Hill makes many valid and important points, but, on occasion, he weakens them by exaggeration. At times his partisan style overcomes his theo· logical substance. The Catholic University of America Washington, D.C. pATRICK GRANFIELD Many Paths: A Catholic Approach to Religious Pluralism. By EUGENE HILLMAN. Maryknoll, New York: Orbis Books, 1989. Pp. 95. A Christian theology of religions raises fundamental epistemological and methodological questions. Hillman comes to the debate from what Lindbeck has called an " experiential expressivist " background, that is, there is a tacit assumption that reality is experienced and then expressed, that reality precedes language rather than being disclosed and shaped through language. When such an outlook is applied to the theology of religions, the outcome is often the " discovery " of a common experience underlying all religions, despite their different expressions. The latter can be seen to vary according to climate, history, temperament, and so on. Such expressions are loose symbols for a 742 BOOK REVIEWS greater reality, which takes on an increasingly vague shape with the demise of the signifier. History can offer very little resistance to such a model, and the conflicts, differences, intractabilities, and real problems of religious plurality are slowly silenced, almost numbed into a drowsy calm. That history refuses to play this role, while theologies of religion are often demanding it, is indicative of the difficulties with such a model. Hillman's first book on this topic (The Wider Ecumenism, 1968) showed him to be a follower of Rahner. He stressed the universality of grace and its mediation through the historical and particular; he thereby argued for a wider ecumenism with regard to the world religions, in a model analogous to intra-Christian ecumenism. In this book, Hillman advances the same position, but now infused with a strong dose of Wilfred Cantwell Smith. He does not confront the theological criticisms made against either of his mentors. The book is divided into four lucid chapters. The first considers the meaning and role of religion, and much of Hillman's discussion is helpful. However, as the chapter proceeds, one finds that the definition of religion is not controlled by the particularities and intractable dif. ferences presented by the subject matter but rather by an experiential essentialism. Hillman uses Smith's distinction between "faith" and " belief " to two ends, one descriptive, the other evaluative. However he, like Cantwell Smith, conflates description with evaluation. Furthermore, he is untroubled that the subject matter under inspection does not easily yield to such distinctions. Descriptively, " belief " or the " cumulative tradition " involves the " myriad historico-cultural par· ticularizations " that go to make up a religion such as liturgies, doc· trines, ethical systems, practices, histories, and so on {20). Faith is basically an experience of " the tr,anscendent, which is presumably the same for every person," and can be distinguished from the "cumulative tradition, which is different for each people, nation or... (shrink)

In lieu of an abstract, here is a brief excerpt of the content:524 BOOK REVIEWS Word is to interpret us" (189). That two-way response to the Word of God neatly summarizes William Hill's witness to us as theologian as well: to he the mediator between classical and contemporary idiomata in such a way as to enrich the deliverances of both, reminiscent of Matthew's commendation of the " disciple in the kingdom of Heaven [being] like a householder who brings out from (...) his storeroom new things as well as old" (13 :52). The excitement of this project will not he lost on students of theology confronted with novel theories periodically renewed. What makes William Hill a theologians' theologian is not only his conceptual clarity, hut his capacity to move among us as a fellow inquirer. Bereft of any need to kill off contenders to make room for his innovations, we rather find him recalling on every page how much he has learned from others and wishes to pass on to us. University of Notre Dame Notre Dame, Indiana DAVID B. BURRELL, c.s.c. The Diversity of Religions: A Christian Perspective. By J. A. D1NoIA, O.P. Washington, D.C.: The Catholic University of America Press, 1992. $29.95 (cloth), $17.95 (paper). For some time now the debate in the Christian theology of religions has centered around the question of ·the possibility of salvation for nonChristians. The answers to this question have often been placed in a threefold typology: exclusivism, inclusivism or pluralism. Exclusivists generally maintain that salvation is conditional on an explicit confession of faith in Jesus Christ, hence non-Christians are lost. Pluralists, on the other hand, maintain that salvation can he found in different religions in various ways, and that Christianity is one among many paths to the divine reality. Inclusivists agree that non-Christians may he saved, and if they are it may he through rather than despite their religion. Inclusivists differ from pluralists in believing that Christ is the constitutive cause of all salvation, even therefore the salvation of a non-Christian. DiNoia's hook claims to do two very significant things. First, to go beyond the three approaches and suggest a fresh way of dealing with the question. Second, in doing so, to create a new agenda for the Christian theology of religions. My verdict: he partly fails and partly succeeds, and both his failings and success are deeply instructive and profoundly illuminating. DiNoia's argument is advanced carefully and lucidly and is acces- BOOK REVIEWS 525 sihle to non-specialists. The bibliographic essay/notes related to each chapter indicate thorough research (with one exception) and are a pleasure to read. DiNoia (a Thomist with Barthian leanings) closely follows George Lindbeck's cultural-linguistic model of religion, arguing that the specific way of life, determined by the actual doctrines held, uniquely shapes and moulds the religious practitioner. The goal and means of the religious way are intrinsically related and cannot he separated. He then persuasively argues that the difficulty with pluralists and inclusivists is that they impose a soteriocentricism upon other religions where there may he none! In contrast, DiNoia maintains one cannot say anything about the meaning of another religion apart from specific and proper attention to the ways in which its doctrines regulate its practice and stipulate the goal to he achieved by that way of life. In Christianity, eternal fellowship with the blessed Trinity can be said to he the goal (salvation) which is carefully orchestrated in minute detail through the liturgical life of the community. To claim that other religions attain the same salvific goal is therefore problematic. DiNoia's argument creates a space for other religions to really disclose what they are about in their doctrines and practice, without a priori categorization, and this is to he welcomed. Hence, the necessity of dialogue as the proper location for disclosure of the "other". Dialogue thereby becomes central to a theology of religions. Only in this process can we ask the question as to whether and how these ways of life relate to Christianity. DiNoia allows for the possibility that doctrinal truth and good actions can he found in other religions, without compromising the cen· trality of the incarnation as constitutive... (shrink)

This book examines the most controversial issues concerning the use of pre-drafted clauses in fine print, which are usually included in consumer contracts and presented to consumers on a take-it-or-leave-it basis. By applying a multi-disciplinary approach that combines consumer's psychology and seller's drafting power in the logic of efficiency and good faith, the book provides a fresh and unconventional analysis of the existing literature, both theoretical and empirical. Moving from the unconscionability doctrine, it criticizes (and in some cases refutes) its (...) main conclusions based on criteria which are usually invoked to sustain the need for public intervention to protect consumers, and specifically related to Law (contract complexity), Psychology (consumer lack of sophistication criterion) and Economics (market structure criterion). It also analyzes the effects of different regulations, such as banning vexatious clauses or mandating disclosure clauses, showing that none of them protect consumers, but in fact prove to be harmful when consumers are more vulnerable, that is whenever sellers can exploit some degree of market power. In closing, the book combines these disparate aspects, arguing that the solution (if any) to the problem of consumer exploitation and market inefficiency associated with the use of contracts of adhesion in these contexts cannot be found in removing or prohibiting hidden clauses, but instead has to take into account the effects of these clauses on the contract as a whole. (shrink)

By questioning the validity of some of our basic concepts, such as space, object, and causality, quantum physics contributes quite decisively to the dramatic changes now taking place in our world picture. Veiled Reality provides a detailed view of the reasons why such a questioning arises, a survey of the corresponding conceptual and theoretical problems, and a comprehensive, up-to-date account, useful to scientists and epistemologists alike, of the various ways present-day physicists tackle these problems.The book deals with the E.P.R. reality (...) criterion, local causality, and quantum measurement including relativistic quantum collapse, decoherence theories, consistent histories approaches, and ontologically interpretable theories. Questions bearing on the connection between counterfactuality and realism, intersubjective agreement, and limits of the bearing of the verbs “to have” and “to be,” follow naturally from the analysis and are thoroughly examined. Finally, distinguishing between empirical reality and a veiled independent reality whose only knowable features are structural yields a clue to a plausible interpretation of current physics.Accessible to readers with only very elementary background in modern physics, Veiled Reality offers nonspecialists, including students in physics and philosophy, easy access to basic problems in the foundation of physics. (shrink)

This paper aims to provide a theoretical framework for explaining the subjective character of pain experience in terms of what we will call ‘embodied predictive processing’. The predictive processing (PP) theory is a family of views that take perception, action, emotion and cognition to all work together in the service of prediction error minimisation. In this paper we propose an embodied perspective on the PP theory we call the ‘embodied predictive processing (EPP) theory. The EPP theory proposes to explain pain (...) in terms of processes distributed across the whole body. The prediction error minimising system that generates pain experience comprises the immune system, the endocrine system, and the autonomic system in continuous causal interaction with pathways spread across the whole neural axis. We will argue that these systems function in a coordinated and coherent manner as a single complex adaptive system to maintain homeostasis. This system, which we refer to as the neural-endocrine-immune (NEI) system, maintains homeostasis through the process of prediction error minimisation. We go on to propose a view of the NEI ensemble as a multiscale nesting of Markov blankets that integrates the smallest scale of the cell to the largest scale of the embodied person in pain. We set out to show how the EPP theory can make sense of how pain experience could be neurobiologically constituted. We take it to be a constraint on the adequacy of a scientific explanation of subjectivity of pain experience that it makes it intelligible how pain can simultaneously be a local sensing of the body, and, at the same time, a more global, all-encompassing attitude towards the environment. Our aim in what follows is to show how the EPP theory can meet this constraint. (shrink)

Purpose. The research is devoted to the analysis of the urgent problem of the information society: the overload of a person with information and, as a result, the impossibility of adequate formation and development of the personality; as well as the problem of "digitization" of human existence and the formation of a new reality of dataism. Theoretical basis. A lot of modern scientific works are devoted to the analysis of the information society, its problems and features. The information society is (...) a logical continuation of the scientific and technological revolution, which led to the rapid growth of scientific knowledge and the technology development. In the 20th century, technologies have touched the sphere of knowledge and information, as a result of which the formation and development of the information society, or "knowledge society", takes place. Information becomes the main resource in it, and, one way or another, a person’s life is inextricably connected with the information space. With the information society formation, the problem of information search and processing becomes one of the most urgent. It turns out that despite the abundance and availability of information, it is very difficult to determine its relevance. A lot of effort is spent on developing information retrieval algorithms. Another problem is related to the person’s inability to process large amounts of data. This situation begins to influence not only the education process and professional activity, but also the formation of a person’s personality. A person is "lost" in the information space and gradually loses his/her "I". Algorithms for data analysis come to the rescue, but gradually, instead of giving a person material for thought, they begin to make decisions on their own, and therefore, live life instead of a person. With the advent of Big Data processing algorithms, a new ideological paradigm appears – dataism, which predicts the merger of a person with the general data flow. Originality. The authors make assumptions that the dataistic future is "natural". A lot of works, including in the framework of philosophy, are focused on the problem of "dissolving" a person in the information space and finding ways to overcome it. But, in our opinion, this process is a completely logical continuation of human evolution. Conclusions. Existence of a person as a data flow is not a problem and a threat, but a new dimension of his/her being, and, therefore, requires a careful study and formulation of the main principles of this form of existence. (shrink)

Screen-based virtual worlds have been described as fundamentally disembodying. Contrary to this, the aim of this article is to provide a phenomenological analysis of bodily presence in one case of screen-based virtuality. By integrating phenomenology with qualitative research methodologies, I explore esports practitioners’ experiences of bodily presence in League of Legends (LoL). Here, descriptions from real-life esports practitioners are analyzed within the phenomenological framework of ‘incorporation’. My analysis shows that the practitioners’ experience and engage with their virtual world not just (...) by incorporating their physical gaming equipment, but also through incorporation of virtual abilities and tools specific to the game world. Having shown that the LoL practitioner’s body spans both physical and virtual space without leaving the body behind, I situate these results within the discussion of virtual presence in video games. I claim that the practitioners’ sense of presence can be accounted for by situating the integrated physical and virtual tools and abilities within the phenomenological framework of the ‘nullpoint’, understood as a bodily field of activity shaped by our incorporated skills and tools. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:BOOK R]]JVIEWS room for different theories and new developments. He does not try to tie up every loose end. Furthermore, he avoids the rut of the specialist by willingly and capably addressing questions of biblical exegesis, philosophy, psychology, science, and popular culture with even-handed competence. Space does not permit me to discuss his fascinating analysis of the psychology of near-death experiences or specific rejoinders to important objections (e.g., the (...) Bible depicts the dead as bodily beings, not immaterial spirits; dualism is a result of the Fall; dualism implies that the whole person does not die; at death we pass out of time, and, hence, there is no intermediate state). But I can assure you that his account is cogent and illuminating. Lenoir-Rhyne College Hickory, North Carolina PHILIP BLOSSER: The Crisis of Liberal Democracy: A Straussian Perspective. Edited by KENNETH L DEUTSCH AND WALTER SOFFER. Albany: State University of New York Press, 1987. Pp. ix+ 304. $54.50 (cloth); $18.95 (paper). For Leo Strauss, the superiority of classical political philosophy over modern social science (and political theory based on social science) lies in at least four principles. First, it treats political matters as they actually appear to man qua philosopher and, in a qualified way, to the good citizen. Because Strauss claims that social science (and much post-classical political philosophy) abstracts from his canon of intelligibility, he thinks that it cannot lead to a humane, rational politics. (See "What is Political Philosophy?", in What is Political Philosophy? [Westport: Greenwood], pp. 27-28, and "Distinction between Facts and Values" in Natural Right and History [Chicago: Univ. of Chicago Press, 1953], pp. 78-80.) Second, Plato and Aristotle believed that only the good man properly judges politics. This belief attracts Strauss, because it identifies virtue as the best claimant to political rule. ("What is Political Philosophy? ", pp. 36-38.) A third principle is derived immediately from this second: politics ought to be organized hierarchically. In the hierarchy, either the truly virtuous or gentlemen should rule, and those having a passive, obediential form of virtue should be the ruled. Fourth, this arrangement is rational and humane. For although the virtues of the ruler and the ruled are complementary in justice and necessary to it, still they are different and, in fact, require the stratification just mentioned. ("Classic Natural Right" in Natural Right and History, pp. 130-44.) BOOK REVIEWS 527 Because of the controversial nature of these principles and Strauss's eminence in political philosophy, one welcomes the present collection of essays by his disciples. They believe that in liberal democracies people confuse liberty with the uses to which liberty can and ought to be put. Doing so, people undermine that regime's foundations. Strauss and his disciples believe that modern natural right makes the clash between liberty and natural right inevitable, because its principal founders, Thomas Hobbes and John Locke, conceived man as non-political. They conceived individuals as gaining certain advantages from governments hut as gaining no good in the exercise of politics itself. Classic natural right, by contrast, bases itself on the assumption that man is radically political. Moreover, it conceives politics as an arena for liberating, ennobling activities. Hobbes and Locke viewed the individual as independent of politics, which they placed at the low end of the range of human activity, along with everyday concerns and popular morality, rather than at the high end, as Strauss would. Thus for Strauss, liberal democracy is founded on modern principles, which are either apolitical and liberal (Locke) or apolitical and illiberal (Hobbes). Consequently, it cannot withstand the individualist and collectivist onslaughts that we have seen in this century. What, then, have Strauss's disciples to say about liberal democracy and the prospect of classic natural right in a Western world which is more or less permanently Hobbesian-Lockean? This can be answered by describing first the hook's divisions and then its diagnoses and prescriptions. In part one the contributors appraise the work of Strauss itself; in part two they define issues in liberalism ; and in part three they discuss liberalism in American political life. In the first part, Michael Platt outlines how Strauss's thought... (shrink)

In lieu of an abstract, here is a brief excerpt of the content:BOOK REVIEWS 719 An Apology for Apologetics: A Study in the Logic of lnterreligious Dialogue. By PAUL J. GRIFFITHS. New York: Orbis, 1991. ISBN: 0 88344 761 4. pp. 113. Jesus Christ at the Encounter of World Religions. By J. DUPUIS. New York: Orbis, 1991 (ET: Robert R. Barr, from French, 1989). ISBN: 0 88344 723 1. pp. 301. Griffiths presents a rigorous argument for the possibility of con· (...) tradictory claims between different religious communities. His inspira· tion, as he acknowledges, is William Christian Snr. His basic argu· ment is: " If representative intellectuals belonging to some specific religious community come to judge at a particular time that some or all of their own doctrine-expressing sentences are incompatible with some alien religious claim(s), then they should feel obliged to engage in both positive and negative apologetics vis-a-vis these alien religious claim(s) and their promulgators" (3). He takes negative apologetics to be a critique of arguments made against one's own religious claims, showing that such arguments fail or are inconsistent or incoherent. Positive apologetics shows how a particular religious community's doctrines are cognitively superior, in some respect(s), to another religious community 's doctrines. It is essential for this enterprise that only methods of argumentation and criteria of knowledge acceptable to the adversary are employed. This requires the acceptance of natural theology. Griffiths is well aware of the lion's den he is entering, as his proposals run counter to much scholarship in the area of interreligious dialogue, so he spends three chapters apologetically tackling the lions. The objectors (who mainly remain in notes) include Derrida, Barthes, Winch, Lindbeck, Hick, Huxley, Nasr, Plantinga and others, although Mac· Intyre is curiously missing. This technique has the advantage of isolating and presenting arguments, without falling into problems of cor· rect exegesis of opponents. And this is also its weakness, as objectors will sometimes feel caricatured or misunderstood-as is surely the case with Plantinga and in one instance, Hick. First, he tackles objections that sentences from one tradition are either incomprehensible or incommensurable with those of another, convincingly showing that the strong versions of both claims are self· defeating and unsustainable. Weaker versions still allow for his proj· ect-or so he thinks. This is where Maclntyre's work should have been considered. Then he tackles various theories of religious language (following Lindbeck's typology). He argues against non-cognitive accounts that reduce beliefs to the credibility of causes for holding beliefs, a position incapable of asserting its truth over other views because of its 720 BOOK REVIEWS own presuppositions. He follows Lindbeck in criticizing experiental expressivism, and then turns upon Lindbeck's own form of rule theory (which is ambivalent regarding cognitive claims), arguing convincingly that to suggest that only sentences uttered confessionally and with performative function can possess ontological truth is confused (42). In a brief review it is not possible to rehearse Griffiths's careful argumentation. Griffiths then sets about tackling two types of universalists: Hick and Huxley. Of Hick, he argues that some criteria are required to discern true from false religions (e.g. Jim Jones) and in so doing such a position needs to support and develop such criteria, thereby effectively introducing apologetics. He neglects to deal with Hick's pragmatic criteria of beneficial ' fruits ' evident in adherents, but the logic of his argument can be applied to Hick's proposals. Using Katz and Zaehner, he argues against the esoteric universalism of the philosophia perennis. (The arguments of Robert Forman's recent book, The Problems of Pure Consciousness, are strangely neglected, despite Griffiths's being a contributor to that collection.) Finally, he tackles objections against positive apologetics-first, on the grounds that it has a negative effect on interreligious relations. Logically, this need not be the case, although Griffiths is well aware that the political context of apologetics can obscure its proper goal: deeper critical understanding, learning and problem solving. Then, in sustained dialogue with Plantinga, he argues against the objection that success is impossible. It is impossible only if " knockdown drag-out" (64) argumentative victory is expected. Griffiths suggests the cumulative -case argument and gives instances of such successful apologetics (medieval... (shrink)

In lieu of an abstract, here is a brief excerpt of the content:530 BOOK REVIEWS I think none of these books contains a wholly satisfactory treatment of the particular issues it takes up. Taken together, however, they do show that evil presents not just one but many problems to reflective religious minds. In addition, they make it perfectly evident that not just one but many academic disciplines continue to have helpful things to say in response to these gripping perplexities. University (...) of Notre Dame Notre Dame, Indiana PHILIP L. QUINN Di,alogue with the Other: The Inter-religious Dialogue. By DAVID TRACY. Louvain Theological and Pastoral Monographs, 1. Louvain : Peeters; Grand Rapids, Mich.: Eerdmans, 1990. Pp. 123. $12.95. With this book David Tracy continues the hermeneutical project he launched in the Analogical Imagination: a concern to converse with the classics and to encounter the ' other '. However, here the ' other ' is extended beyond the traditional Western classics to the religions of the world and the often neglected archaic traditions. Tracy is surely correct when he says: " I believe that we are fast approaching the day when it will not be possible to attempt Christian systematic theology except in serious conversation with the other great ways" (p. xi). Here he follows a pioneering line drawn in Chicago by Tillich, Eliade and Kitagawa. Tracy brings to this venerable tradition his particular concern with hermeneutics and his experience with Jewish-Christian and Buddhist-Christian dialogue. The essays are further united by Tracy's desire to restore the unity between the mystical and prophetic within the Christian tradition. Employing Kenneth Burke's analysis of rhetoric, Chapter one shows that Freud and Lacan can be interpreted in terms of a clash of prophetic and mystical rhetorics respectively. Both are concerned with the ' other ', Freud more instrumentally and didactically and Lacan more subversively and anarchically but not nihilistically or in the way of Zen. In this chapter Tracy has a tendency towards overdetermination. Still, the brunt of his argument is that all discourse has concealed foundations, the archaeology of which will help illuminate the opera· tive rhetoric. Furthermore, the mystical/prophetic typology used in religion can illuminate secular issues, viz., the debate between Freud and Lacan. However, Tracy does not pay full attention to the nature of the 'other', but too easily assimilates it. For instance, is Freud's attention to the subconscious analogous to religious rhetoric's regarding the otherness of God? And does it really serve Tracy's purpose to start BOOK REVIEWS 531 the book by remammg within such very western waters despite the brave navigational direction he charted in the introduction? Chapter two revisits the classics: he uses the writings of William James to throw light on the criteria for interreligious dialogue. These criteria are used to affirm the authenticity of religions; these are not intended to " replace the dialogue but, at best, heuristically to inform it" (p. 27). Tracy offers a good and sensitive appreciation of James (despite his anachronistic elements), but his conclusions are somewhat thinly related to James's work and relate more closely to Tracy's own hermeneutical approach. The three criteria that he advances are: first, the notion of " immediate luminousness," understood as manifestation in a Heideggerian sense (and in keeping with von Balthasar) ; second, the necessity of coherence, understood as the compatibility of religious belief with science, art, and other humanistic traditions; and third, an ethical-pragmatic criterion related to James's notion of "fruits." With regard to the second, Tracy is aware of the problem of assuming a neutral form of "reason" in adjudicating such coherence. Still, his study would have been more helpful with specific examples to highlight some of the intractable problems in such a task. For instance, autonomy has been granted to the sciences by most western Christians but has not been by some other religious traditions in certain parts of the world, and so the notion of coherence begs the question. Tracy needs to grapple with the issues raised by Macintyre and Winch (among others) to move beyond the potentially sterile dichotomy implied in his notion of coherence. With regard to the third criterion there is question begging, too. Would Abraham have passed this test in his willingness to kill his son? Or... (shrink)

First published in 1993. Routledge is an imprint of Taylor & Francis, an informa company.

We are immersed within an odorous sea of chemical currents that we parse into individual odors with complex structures. Odors have been posited as determined by the structural relation between the molecules that compose the chemical compounds and their interactions with the receptor site. But, naturally occurring smells are parsed from gaseous odor plumes. To give a comprehensive account of the nature of odors the chemosciences must account for these large distributed entities as well. We offer a focused review of (...) what is known about the perception of odor plumes for olfactory navigation and tracking, which we then connect to what is known about the role odorants play as properties of the plume in determining odor identity with respect to odor quality. We end by motivating our central claim that more research needs to be conducted on the role that odorants play within the odor plume in determining odor identity. (shrink)

Originally published in 1986. Both moral philosophers and philosophical psychologists need to answer the question ‘what is a virtue?’ and the best answer so far give is that of Aristotle. This book is a rigorous exposition of that answer. The elements of Aristotle’s doctrine of virtue are scattered throughout his writings; this book reconstructs his complex and comprehensive doctrine in one place. It also covers Aristotle’s views about choice, character, emotions and the role of pleasure and pain in virtue. The (...) celebrated function is considered carefully as well as the doctrine of virtue being related to Aristotle’s metaphysics and categories. (shrink)

Shortages of new therapeutics to treat coronavirus disease (COVID-19) have forced clinicians, public health officials, and health systems to grapple with difficult questions about how to fairly allocate potentially life-saving treatments when there are not enough for all patients in need (1). Shortages have occurred with remdesivir, tocilizumab, monoclonal antibodies, and the oral antiviral Paxlovid (2) -/- Ensuring equitable allocation is especially important in light of the disproportionate burden experienced during the COVID-19 pandemic by disadvantaged groups, including Black, Hispanic/Latino and (...) Indigenous communities, individuals with certain disabilities, and low-income persons. However, many health systems have resorted to first-come, first-served approaches to allocation, which tend to disadvantage individuals with barriers in access to care (3). There is mounting evidence of racial, ethnic, and socioeconomic disparities in access to medications for COVID-19 (4, 5). -/- One potential method to promote equitable allocation is to use a weighted lottery, which is an allocation strategy that gives all eligible patients a chance to receive the scarce treatment while also allowing the assignment of higher or lower chances according to other ethical considerations (6). We sought to assess the feasibility of implementing a weighted lottery to allocate scarce COVID-19 medications in a large U.S. health system and to determine whether the weighted lottery promotes equitable allocation. (shrink)