Uncertainty for policy makers is not new but the pressure to make decisions under conditions of uncertainty is perhaps greater than ever. The arrival of new scientific developments such as pharmacogenetics offers potentially great benefits . They have passionate supporters as well as doubters. The evidence is often extensive but unclear and policy makers may find themselves under pressure to make decisions before they feel that the evidence is compelling.The UK is particularly well placed to play a leading role in (...) the development of pharmacogenetics and is equally well placed to derive the benefits to both health and wealth that could flow from this. However, the uncertainties threaten to overwhelm the capacity of policy makers to act effectively. The uncertainties are both about the context within which the science and delivery of pharmacogentics is being developed and about the interests that could be served. This paper maps these uncertainties and concludes with some suggestions, drawing on deliberative democracy and futures thinking, as to how policy makers might manage the tensions and dilemmas they face by moving from an unstable, emergent policy arena to a more stable one. (shrink)

More than twenty years after its original publication, _The Case for Animal Rights _is an acknowledged classic of moral philosophy, and its author is recognized as the intellectual leader of the animal rights movement. In a new and fully considered preface, Regan responds to his critics and defends the book's revolutionary position.

Metaphysics-first approaches dominate the current literature in the epistemology of modality. According to metaphysics-firsters, metaphysical theses have an important role in the justification of modal epistemologies. For example, the thesis that essentialist truths constitute the metaphysical grounds of modal truths is meant to have an important role in the justification of essentialist modal epistemologies. In this article, we argue against this approach. We first pick up some of the groundwork on behalf of the metaphysics-firsters and explicitly spell out potential arguments (...) for their view. However, despite some initial plausibility, these arguments are ultimately found wanting. We conclude that the metaphysics-first approach lacks motivation and puts far too stringent demands upon modal epistemologists. (shrink)

Tom Sparrow shows how, in the 21st century, speculative realism aims to do what phenomenology could not: provide a philosophical method that disengages the human-centred approach to metaphysics in order to chronicle the complex realm of nonhuman reality. -/- Through a focused reading of the methodological statements and metaphysical commitments of key phenomenologists and speculative realists, Sparrow shows how speculative realism is replacing phenomenology as the beacon of realism in contemporary Continental philosophy.

A conception of an environmental ethic is set forth which involves postulating that nonconscious natural objects can have value in their own right, independently of human interests. Two kinds of objection are considered: those that deny the possibility of developing an ethic ofthe environment that accepts this postulate, and those.that deny the necessity of constructing such an ethic. Both types of objection are found wanting. The essay condudes with some tentative remarks regarding the notion of inherent value.

Supporters of eliminative connectionism have argued for a pattern association-based explanation of language learning and language processing. They deny that explicit rules and symbolic representations play any role in language processing and cognition in general. Their argument is based to a large extent on two artificial neural network (ANN) models that are claimed to be able to learn the past tenses of English verbs (Rumelhart & McClelland, 1986, Parallel distributed processing, Vol. 2, Cambridge, MA: MIT Press; MacWhinney & Leinbach, 1991, (...) Cognition, 40, 121-157). In this article we critically review Rumelhart and McClelland's as well as MacWhinney and Leinbach's ANN models and conclude that they do not succeed in the assigned task of learning the past tenses of English verbs. In order to answer their challenge to the symbolic processing approach, we present our symbolic pattern associator (SPA)-a general-purpose pattern associator that can learn to associate arbitrary discrete patterns. We carried out several experiments with the SPA using the same set of verbs that was used in MacWhinney and Leinbach's simulation with more realistic training and testing procedures. The SPA outperformed the connectionist models by a wide margin in the accuracy of learning, and successful inductive generalizations to unseen verbs. Our SPA has very natural and psychologically realistic explanations to many psychological effects such as U-shaped learning curve, and is much closer to human subjects in predicting past tense of the pseudo-verbs. In contrast to ANNs, whose internal representations are entirely opaque, the SPA can represent the acquired knowledge in the form of production rules that allow for further higher-level processing and integration, resulting in linguistically realistic associative templates for irregular verbs and production rules for regular verbs. In the light of these findings, we conclude that eliminative connectionists' vision of cognition as simple pattern association and pattern recognition without symbolic representation is inadequate. Pattern association as such does not imply rule-less or cue-based models of language acquisition or of human learning in general. (shrink)

ABSTRACTWe examine Marx's critiques of language, politics, and capitalist political economy and show how these anticipated critical discourse and argumentation analysis and ‘cultural political economy’. Marx studied philology and rhetoric at university and applied their lessons critically. We illustrate this from three texts. The German Ideology critically explores language as practical consciousness, the division of manual and mental labor, the state, hegemony, intellectuals, and specific ideologies. The Eighteenth Brumaire studies the semantics and pragmatics of political language and how it represents (...) the class content of politics and contributes to social transformation. Capital deconstructs the categories of classical political economy and their constitutive role in capitalist social relations. This is one aspect of CPE. Capital also highlights the structural and agential aspects of these relations, their contradictory dynamic, and their crisis-prone character. We comment on this aspect too. This said, Marx held that social transformation is mediated through political imaginaries and highlighted the need for the proletariat to develop a ‘poetry’ of the future. We then consider the misleading ‘base-superstructure’ metaphor and note how, against the thrust of Marx's work, it tends to reify culture. The article concludes that Marx contributed to the critique of semiotic as well as political economy. (shrink)

This study exploratively conducted two investigations of timbre influenced by harmonic loudness. Investigation 1 examined piano timbre preference between non-processed melodies and two kinds of adjustments created via an equalizer–a basic tool used for sound engineering and for producing audio materials. Using the paired comparison method, 98 respondents were surveyed. The results show that in the bass range of the piano sound, the preferred audio material was that produced via an equalizer by reducing the loudness of the 7th and 9th (...) harmonics by 15 dB, while enhancing the loudness of the 8th harmonic by 15 dB. Investigation 2 examined three degrees of the processed melodies—adjusting the harmonics by 15, 10, and 5 dB. The results show that the 15 dB change was the best, while the 10 dB change was the worst. These results provide a new approach to improving the sound timbre for sound engineering and artificial intelligence music production. (shrink)

_Uses the concept of religiosity to challenge traditional views of Nietzsche and Zhuangzi as nihilistic and anti-religious._.

Tom Campbell is well known for his distinctive contributions to legal and political philosophy over three decades. In emphasising the moral and political importance of taking a positivist approach to law and rights, he has challenged current academic orthodoxies and made a powerful case for regaining and retaining democratic control over the content and development of human rights. This collection of his essays reaches back to his pioneering work on socialist rights in the 1980s and forward from his seminal book, (...) The Legal Theory of Ethical Positivism (1996). An introductory essay provides an historical overview of Professor Campbell's work and argues for the continuing importance of 'democratic positivism' at a time when it is again becoming clear that courts are ineffective protectors of human rights. (shrink)

This chapter describes how philosophical theorizing about justice can be connected with empirical research in the social sciences. We begin by drawing on some received distinctions between ideal and non-ideal approaches to theorizing justice along several different dimensions, showing how non-ideal approaches are needed to address normative aspects of real-world problems and to provide practical guidance. We argue that there are advantages to a transitional approach to justice focusing on manifest injustices, including the fact that it enables us to set (...) aside some reasonable disagreements about justice. The ‘bottom-up’ approach we advocate, for which we borrow Wolff’s term ‘real-world political philosophy’, is an empirically-informed normative analysis that attends to specific, identifiable injustices, and thus is partial, though not isolationist. We illustrate our approach by considering how different models of the nature of disability suggest different kinds of remedy for injustices faced by persons living with disabilities. We reflect on the nature and significance of vulnerabilities, and we assess the role of public opinion in normative theorizing, suggesting a particular significance for the opinions and experiences of marginalized groups. We finally reflect on the relevance of European legal and institutional frameworks for theorizing justice in Europe. (shrink)

This study was conducted to address the concept of higher education curricula and its practice from an ecological perspective. First, the significance of ecology is investigated based on two streams of thought; the ecological concept of the university proposed by Ronald Barnett; and the text, The Three Ecologies authored by the Italian philosopher Félix Guattari. Second, the notion of ecology is explored, and thoughts on the ecological curriculum and its feasibility are elaborated. Third, outcome-based education is currently the predominant curriculum (...) practice applied in higher education. From an ecological perspective, this learning approach is insufficient. Finally, the practices used for achieving an ecological connection of curricula in higher education are discussed with particular regard to curriculum organisation, the learning process and students’ role as global citizens. (shrink)

Consumer indirect misbehavior in access-based consumption is a significant challenge for enterprises. The literature is in short of a deep understanding of the antecedent conditions of consumer indirect misbehavior in this context and limited by inconsistent findings, calling for developing a holistic and integrative theoretical framework. This study integrates three commonly used theoretical perspectives in the consumer misbehavior literature to present holistic archetypes of consumer indirect misbehavior formation. In accordance with this theoretical objective, we adopted an emerging approach for configurational (...) analysis, i.e., fuzzy-set qualitative comparative analysis, to analyze the complex combinations of six influencing factors. We collected data using a scenario-based field survey of 264 experienced consumers of a popular bike-sharing service in China. The scenarios were developed based on relevant literature and a Delphi study. The fsQCA results reveal multiple configurations for high and low levels of consumer misbehavior intention. Specifically, perceived benefits and moral definition play important roles, while the effect of sanctions is highly dependent on other factors. These results lead us to derive three theoretical propositions for antecedent conditions leading to consumers’ indirect misbehavior intentions in access-based consumption. This study enriches our understanding of the causes of misbehavior and provides novel insights for management practitioners to take appropriate countermeasures. (shrink)

We present a research on smart city planning and community governance using dynamic game methods, analyze the current status and problems of the current smart community service system, and put forward countermeasures and suggestions based on the global smart community development experience. Through smart city planning and construction, the game model of government governance and information sharing between communities and decision making is obtained, and the two-dimensional replication dynamic system equations of smart city planning and construction agencies and communities are (...) obtained from smart city planning and construction. The evolutionary stability strategy and a united front are analyzed. The strategy achieves the ideal stable conditions. We define the relevant definition of a smart community and discuss the purpose and significance of the research, especially the importance and necessity of the construction of the smart community. Based on the current situation of the construction of smart communities, we conduct specific research, discuss the deficiencies and shortcomings in the current construction of smart communities, and find out the causes of these problems. Finally, based on learning from the relevant work experience, corresponding improvement measures are proposed for the existing problems from the united front, top-level design, social participation, platform construction, and talent training. (shrink)

There are increasing concerns that research regulatory requirements exceed those required to manage risks, particularly for low- and negligible-risk research projects. In particular, inconsistent documentation requirements across research sites can delay the conduct of multi-site projects. For a one-year, negligible-risk project examining biobank operations conducted at three separate Australian institutions, we found that the researcher time required to meet regulatory requirements was eight times greater than that required for the approved research activity. In total, 76 business days were required to (...) obtain the necessary approvals, and site-specific processes required twice as long as primary Human Research Ethics Committee and Research Governance Office processes. We describe the impact of this administrative load on the conduct of a one-year, externally-... (shrink)

This article presents counter evidence against Smolensky's theory that human intuitive/nonconscious congnitive processes can only be accurately explained in terms of subsymbolic computations carried out in artificial neural networks. We presentsymboliclearning models of two well‐studied, complicated cognitive tasks involving nonconscious acquisition of information: learning production rules and artificial finite state grammars. Our results demonstrate that intuitive learning does not imply subsymbolic computation, and that the already well‐established, perceived correlation between “conscious” and “symbolic” on the one hand, and between “nonconscious” and (...) “subsymbolic” on the other, does not exist. (shrink)

An advertiser develops visual associations of signs and symbols to create a product image that motivates consumers. Today is characterized by a solid consumer culture based on visual identity consumption that articulates and interacts with each consumer's daily actions, words, and visual perceptions. The frequent use of female role portrayals and physical attractiveness in advertising contributes to an increase in society's awareness of women. Some scholars have developed an ethical discussion out of the phenomenon of female role portrayals not matching (...) the public expectations because the portrayals are too narrowly defined and women are unfavorably depicted. But another group has studied the product-type match-up hypothesis, which emphasizes effectively employing attractive female endorsers that closely match the product type. The shift in female social status in Taiwan contributes to the importation of foreign ideas such as feminine values, rituals, and esthetics. Women in Taiwan have been introduced to a new feminism, a modified perception of appropriate personal appearance and behavior. This current research utilizes content analysis and in-depth interviews to explore contemporary female role portrayals in advertising. In addition, this article examines the relationship between the formation of contemporary physical attractiveness and visual consumption in advertising. The results reveal that most endorsers were celebrities, with fit bodies and pleasant expressions, portrayed as product users who offer personal experiences to deliver product knowledge. Conservation classical beauty was the most common depiction, while sexual expression was the least common. Finally, this article recommends that different types of beauty, posture, and appeal should be carefully selected to match domestic and foreign magazines' readers. (shrink)

In the aftermath of the 2008 financial crisis, Bitcoin emerged as an alternative monetary system that could circumvent political and financial authorities. A practice in libertarian prefigurative politics, Bitcoin demonstrates the capacity for online subgroups to creatively appropriate internet-based technologies to enact alternative futures. Andrew Feenberg’s critical theory of technology clarifies this capacity and outlines the significance of agency in technical action. As technology mediates many social relations, it has a significant role in the reproduction of social power. Technological agency (...) is therefore a crucial site of resistance in which users can form alternative, democratic rationalizations of technology. Yet are such instances of agency intrinsically democratic? In analysing this aspect of Feenberg’s theory, this article argues that Bitcoin represents a ‘popular rationalization’ of technology – a creative appropriation of technology that empowers some groups while lacking the ethical justification necessary to be considered democratic. (shrink)

The creation of a sense of place has emerged as a goal of many community development initiatives. However, little thought has been given to the role of physical spaces in the shaping of possible senses of place. This article examines three Canadian examples of community sustainable development initiatives to demonstrate that sense of place can be shaped and constrained by the geographical and environmental features of the physical space a community occupies. This finding suggests that a 'one-size-fits-all' approach to community (...) sustainable development is unlikely to be successful; a community's sustainable development ethic will be informed by geography. However, there is some evidence that a strong individual sense of place shaped by local space may act as a barrier to the acceptance of new people and ideas. Conversely, a strong sense of place can result in mobilization for sustainable development initiatives. (shrink)

here has been a large number of studies in neurological sciences on how human brain works, especially in reading and parallel information processing. So I think this statement is really sweeping. Perhaps it is better to knowledge the abilities of human brains and to comment on the limitations of the human brain. The book “Adapt” by Tim Hartford advocates micro-step changes. An important aspect in this area is to understand the processes involved behind the scenes so that it gives us (...) a better formulation of the creativity algorithms involved. I will try to put in some pointers on the depths to which higher level intelligence has been simulated by AI in the past years. Some of the higher level intelligence mechanisms such as creativity, dreams and logical thinking have been implemented in machines in certain ways. However, they are still not implemented in the way humans do the same. The exact mechanism in which these intelligence mechanisms are used by human brains is still way ahead of that done by computers. However, we now look at other aspects in them as well as other functions which might be explored in the years ahead in AI. (shrink)

The claim that mind is an epiphenomenon of the nervous system became academically respectable during the 19thcentury. The same period saw the establishment of an ideal of science as institutionalized endeavour conducted in laboratories. This article identifies three ways in which the ‘physiological psychology’ movement in Britain contributed to the latter process: first, via an appeal to the authority of difficult-to-access sites in the analysis of nerves; second, through the constitution of a discourse internal to it that privileged epistemology over (...) ontology; and third, in its articulation of a set of rhetorical tools that identified laboratories as economically productive institutions. Acknowledging the integral place of physiological psychology in the institution of science, it is claimed, has the potential to alter our understanding of the significance of current neurological science for historical scholarship. (shrink)

Nations, as the hitherto highest level of human groupings, have their varied internal organizational structures featuring functionally differentiated yet interactive arrangements among three leading human institutions: economy, polity, and social life. An internal organizational structure affects the different members of a human grouping in different ways due to institutional exclusion that is inevitably the prerequisite for any human organization. With that in mind, this paper moves beyond ethnocentric confines to suggest an institutionalist understanding of the concepts of modernity and modernization, (...) and discusses the issue of institutional exclusion and its four leading patterns in the era of globalization. (shrink)

The question of whether free will exists has been debated extensively for centuries. Instead of debating this complex issue, recent work in psychology has sought to understand the consequences of beliefs in free will. That is, how are people’s behaviors influenced when they either believe or do not believe in free will? Amongst many outcomes, research has identified free will beliefs to influence achievement, perseverance, and aggressiveness. We believe that beliefs in free will could also exert influence on health behaviors. (...) Health promotion from a psychological perspective has typically adopted social cognitive models to understand and predict health behaviors. We contend that free will beliefs could be included in these models to understand and change health behavior. We provide examples of how a popular social cognition theory, the theory of planned behavior, could be aligned with beliefs in free will. We suggest that the relationship between free will beliefs and theory constructs (attitude, subjective norm, perceived behavioral control, intention) could be positive in health enhancing behaviors and negative in health risk behaviors. Experimentally testing these relationships is needed in future research. This may provide further insights into the consequences of free will and contribute to the explanation of health behavior. (shrink)

ArgumentThis paper arrives at a normative position regarding the relevance of Henri Bergson's philosophy to historical enquiry. It does so via experimental historical analysis of the adaptation of cinematographic devices to physiological investigation. Bergson's philosophy accorded well with a mode of physiological psychology in which claims relating to mental and physiological existence interacted. Notably however, cinematograph-centered experimentation by British physiologists including Charles Scott Sherrington, as well as German-trained psychologists such as Hugo Münsterberg and Max Wertheimer, contributed to a cordoning-off of (...) psychological from physiological questioning during the early twentieth century. Bergson invested in a mode of intellectual practice in which psychological claims had direct relevance to the interpretation of physiological nature. The in-part cinematograph-inspired breakdown of this mode had significance for subsequent interpretations of his philosophy. It is suggested that this experimental particularization of Bergson's contentions indicates that any adaptation of his thought for historical enquiry must be disciplinarily specific. (shrink)

Facial fat grafting techniques often offer impressive surgical results. However, fatal complications, such as irreversible cerebral ischemia, blindness, and hemiplegia are associated with them. We have presented a case report of a patient who presented with a massive cerebral infarction, a serious complication of facial autologous fat injection. The patient was a 28-year-old female who experienced motor dysfunction of the left extremities, which was accompanied with loss of consciousness immediately following fat grafting for facial augmentation. Imaging studies suggested that the (...) patient had a large cerebral infarction on the right frontal, temporal, and parietal lobes due to complete occlusion of her right external carotid artery. Emergency decompressive craniectomy was completed in addition to multiple follow-up medical treatments. The patient recovered after 4 months with reduced motor function in her left upper extremity. This report further summarizes published cases of massive cerebral ischemia after facial injection of autologous fat, as well as lists high-risk facial areas and critical warnings. (shrink)

The word mysticism serves to draw attention to certain similarities in religious experience in both Western and Eastern religion, and it is difficult to find a really satisfactory substitute. What is important is that we should not suppose it to be a simple term, but should recognise that it has many variations. There are varieties of mysticism, recognisable by a certain family resemblance, and it is probably safer therefore to use the word with some qualifying adjective, e.g. Christian mysticism, Jewish (...) mysticism, and so on. (shrink)

AimResting state functional magnetic resonance imaging was used to analyze changes in functional connectivity within various brain networks and functional network connectivity among various brain regions in patients with high myopia.Methodsrs-fMRI was used to scan 82 patients with HM and 59 healthy control volunteers matched for age, sex, and education level. Fourteen resting state networks were extracted, of which 11 were positive. Then, the FCs and FNCs of RSNs in HM patients were examined by independent component analysis.ResultsCompared with the HC (...) group, FC in visual network 1, dorsal attention network, auditory network 2, visual network 3, and sensorimotor network significantly increased in the HM group. FC in default mode network 1 significantly decreased. Furthermore, some brain regions in default mode network 2, default mode network 3, auditory network 1, executive control network, and significance network increased while others decreased. FNC analysis also showed that the network connection between the default mode network and cerebellar network was enhanced in the HM group.ConclusionCompared with HCs, HM patients showed neural activity dysfunction within and between specific brain networks, particularly in the DMN and CER. Thus, HM patients may have deficits in visual, cognitive, and motor balance functions. (shrink)

A superb example of the bookmaker's and translator's art, this new edition of Plato's _Symposium_ exhibits aesthetic, literary, and intellectual excellences rarely found together in a single volume. Tom Griffith's translation of this foundation work of Western culture is unsurpassed for the balance it achieves between readability and fidelity to Plato's Greek. For felicity of phrasing, freshness, care to match the sense of the Greek rather than its wording, and for its idiomatic rendering of the spoken word, it has no (...) peer. Originally published in a limited edition with facing Greek and color wood engravings, Griffith's translation is here presented in reduced format that retains the aesthetic quality of the original version at an affordable price. (shrink)

The slogan “the personal is political” captures the distinctive challenge to the public-private divide posed by contemporary feminists. As such, feminist activism is not necessarily congruent with civic engagement, which is predicated on the paradoxical need to both bridge and sustain the public-private divide. Lee argues that rather than subverting the divide, the politics of the personal offers an alternative understanding of civic engagement that aims to reinstate individuals’ dignity and agency.