Polarity is an inherent feature of almost all prokaryotic and eukaryotic cells. In most eukaryotic cells, growth polarity is due to the assembly of actin‐based growing domains at particular locations on the cell periphery. A contrasting scenario is that growth polarity results from the establishment of non‐growing domains, which are actively maintained at opposite end‐poles of the cell. This latter mode of growth is common in rod‐shaped bacteria and, surprisingly, also in the majority of plant cells, which elongate along the (...) apical–basal axes of plant organs. The available data indicate that the non‐growing end‐pole domains of plant cells are sites of intense endocytosis and recycling. These actin‐enriched end‐poles serve also as signaling platforms, allowing bidirectional exchange of diverse signals along the supracellular domains of longitudinal cell files. It is proposed that these actively remodeled end‐poles of elongating plant cells remotely resemble neuronal synapses. BioEssays 25:569–576, 2003. © 2003 Wiley Periodicals, Inc. (shrink)

Traces the development of recursive functions from their origins in the late nineteenth century to the mid-1930s, with particular emphasis on the work and influence of Kurt Gödel.

First I argue that the prohibition of linguistic self-reference as a solution to the antinomy problem contains a pragmatic contradiction and is thus not only too restrictive, but just inconsistent (chap.1). Furthermore, the possibilities of non-restrictive strategies for antinomy avoidance are discussed, whereby the explicit inclusion of the – pragmatically presuposed – consistency requirement proves to be the optimal strategy (chap.2). The central question here is that about the actual reason for antinomic structures. It turns out to be a form (...) of negative self-conditioning (chap.3). This makes it necessary to clarify the status of negative concepts (chap.4). The generalization of these considerations (chap.5) leads to the actual analysis of the antinomic basic structure (chap.6): Decisively for the pragmatics of the concept is that it positively owns a meaning, so that positivity is always constituted by the concept qua concept. Thus a negative concept is characterized by a fundamental ambivalence: From a semantic point of view it has negative character, in its pragmatic status as a concept, however, it has positive character. If the meaning is especially that of a negative self-reference, the ambivalence leads to the antinomic constellation of a negative self-condition – that is the crux of the matter here! The concept thus possesses the property defined by it exactly when it does not possess it and vice versa. A closer analysis shows that the function of reflective structures for the occurrence of antinomies has to be judged much more differentiated than previous opinions suggest. Not only are four forms of reflectivity to be distinguished in this context – ontic, semantic, pragmatic reflectivity, and especially the form of negative self-condition; but it is also apparent that these are intertwined with each other in a way that is difficult to be understood. The astonishing variety of relationships associated with this makes the irritation that has always emanated from the antinomy problem appear more comprehensible. In the developed pragmatic perspective furtheron parallels to the structure of self-consciousness become visible (chap.7). I conclude with considerations about the significance of the antinomic structure for the problem of dialectics, especially for the synthesis formation of mutually exclusive terms (chap.8). ---------- Zunächst wird gezeigt, dass das Verbot sprachlicher Selbstreferenz als Lösung des Antinomienproblems einen pragmatischen Widerspruch enthält und damit nicht nur zu restriktiv, sondern geradezu inkonsistent ist (Kap.1). Ferner werden Möglichkeiten nicht-restriktiver Strategien zur Antinomienvermeidung diskutiert, wobei sich die explizite Einbindung der – pragmatisch präsupponierten – Konsistenzforderung als optimale Strategie erweist (Kap.2). Zentral ist hier die Frage nach dem eigentlichen Grund antinomischer Strukturen. Er erweist sich als eine Form von negativer Selbst-Bedingung (Kap.3). Dies nötigt zu einer Klärung des Status negativer Begriffe (Kap.4). Die Verallgemeinerung dieser Überlegungen (Kap.5) leitet über zur eigentlichen Analyse der antinomischen Grundstruktur (Kap.6): Entscheidend zur Pragmatik des Begriffs gehört, dass ihm eine Bedeutung positiv zukommt, sodass durch den Begriff qua Begriff stets auch Positivität konstituiert ist. Dadurch ist ein negativer Begriff durch eine prinzipielle Ambivalenz gekennzeichnet: In semantischer Hinsicht hat er negativen Charakter, in seinem pragmatischen Status als Begriff hingegen positiven Charakter. Ist die Bedeutung insbesondere die eines negativen Selbstbezugs, führt die Ambivalenz zur antinomischen Konstellation einer negativen Selbst-Bedingung – das ist hier der springende Punkt! Der Begriff besitzt so die durch ihn definierte Eigenschaft genau dann, wenn er sie nicht besitzt und umgekehrt. Die nähere Analyse zeigt, dass hierbei die Funktion reflexiver Strukturen für das Auftreten von Antinomien weitaus differenzierter zu beurteilen ist, als bisherige Auffassungen nahelegen. Nicht nur dass in diesem Kontext vier Formen von Reflexivität – ontische, semantische, pragmatische Reflexivität und insbesondere auch die Form negativer Selbstbedingung – unterschieden werden müssen; es zeigt sich auch, dass diese in schwer durchschaubarer Weise ineinander verschränkt sind. Die damit verbundene erstaunliche Beziehungsvielfalt läßt die Irritation, die seit je vom Antinomienproblem ausging, begreiflicher erscheinen. In der entwickelten pragmatischen Perspektive werden ferner Parallelen zur Struktur von Selbstbewußtsein sichtbar (Kap.7). Ich schließe mit Überlegungen zur Bedeutung der antinomischen Struktur für das Problem der Dialektik, insbesondere zur Synthesebildung einander ausschließender Bestimmungen (Kap.8). (shrink)

[[[ (Here only the chapters 3 – 8, see *** ) First I argue that the prohibition of linguistic self-reference as a solution to the antinomy problem contains a pragmatic contradiction and is thus not only too restrictive, but just inconsistent (chap.1). Furthermore, the possibilities of non-restrictive strategies for antinomy avoidance are discussed, whereby the explicit inclusion of the – pragmatically presuposed – consistency requirement proves to be the optimal strategy (chap.2). ]]] The central question here is that about the (...) actual reason for antinomic structures. It turns out to be a form of negative self-conditioning (chap.3). This makes it necessary to clarify the status of negative concepts (chap.4). The generalization of these considerations (chap.5) leads to the actual analysis of the antinomic basic structure (chap.6): Decisively for the pragmatics of the concept is that it positively owns a meaning, so that positivity is always constituted by the concept qua concept. Thus a negative concept is characterized by a fundamental ambivalence: From a semantic point of view it has negative character, in its pragmatic status as a concept, however, it has positive character. If the meaning is especially that of a negative self-reference, the ambivalence leads to the antinomic constellation of a negative self-condition – that is the crux of the matter here! The concept thus possesses the property defined by it exactly when it does not possess it and vice versa. A closer analysis shows that the function of reflective structures for the occurrence of antinomies has to be judged much more differentiated than previous opinions suggest. Not only are four forms of reflectivity to be distinguished in this context – ontic, semantic, pragmatic reflectivity, and especially the form of negative self-condition; but it is also apparent that these are intertwined with each other in a way that is difficult to be understood. The astonishing variety of relationships associated with this makes the irritation that has always emanated from the antinomy problem appear more comprehensible. In the developed pragmatic perspective furtheron parallels to the structure of self-consciousness become visible (chap.7). I conclude with considerations about the significance of the antinomic structure for the problem of dialectics, especially for the synthesis formation of mutually exclusive terms (chap.8). (shrink)

In Part 1 the reader is introduced to some standard systems of modal logic and encouraged through a series of exercises to become proficient in manipulating these logics. The emphasis is on possible world semantics for modal logics and the semantic emphasis is carried into the formal method, Jeffrey-style truth-trees. Standard truth-trees are extended in a simple and transparent way to take possible worlds into account. Part 2 systematically explores the applications of modal logic to philosophical issues such as truth, (...) time, processes, knowledge and belief, obligation and permission. Accessible, authoritative, and assured, Modal Logics and Philosophy requires no more background than the completion of a standard introductory logic course. It will be welcomed not only by students looking for a bridge between introductory logic texts and the high-level technical literature but as a guide to, and exploration of, work at the forefront of logic and philosophy. (shrink)

The first edition, published by Acumen in 2000, became a prescribed textbook on modal logic courses. The second edition has been fully revised in response to readers' suggestions, including two new chapters on conditional logic, which was not covered in the first edition. "Modal Logics and Philosophy" is a fully comprehensive introduction to modal logics and their application suitable for course use. Unlike most modal logic textbooks, which are both forbidding mathematically and short on philosophical discussion, "Modal Logics and Philosophy" (...) places its emphasis firmly on showing how useful modal logic can be as a tool for formal philosophical analysis. In part 1 of the book, the reader is introduced to some standard systems of modal logic and encouraged through a series of exercises to become proficient in manipulating these logics. The emphasis is on possible world semantics for modal logics and the semantic emphasis is carried into the formal method, Jeffrey-style truth-trees. Standard truth-trees are extended in a simple and transparent way to take possible worlds into account. Part 2 systematically explores the applications of modal logic to philosophical issues such as truth, time, processes, knowledge and belief, obligation and permission. (shrink)

Thanks to the editorial work of David Pacini, the lectures appear here with annotations linking them to editions of the masterworks of German philosophy as they ...

The present investigation brings into view the philosophy of nature of German Idealism, a philosophical movement which emerged around the beginning of the nineteenth century. German Idealism appro- priated certain motivations of the Kantian philosophy and developed them further in a "speculative" manner (Engelhardt 1972, 1976, 2002). This powerful philosophical movement, associated above all with the names of Fichte, Schelling and Hegel - and moreover having nothing whatsoever to do with the "subjective idealism" of George Berkeley - was replaced by (...) philosophical positions designated roughly as metaphysics of the will, Marxism, life-philosophy, phenomenology and existentialism, as well as positivism, empiricism, philosophy of science, the linguistic turn, and analytic philosophy. These philosophical positions more or less still shape us today. German Idealism amounts to a virtual intellectual-historical antithesis to these movements and thus presents itself in retrospect as a striking alternative. The basis of Idealism - in its various respective forms - is the ideal <Ideelle>, and thus the opposite of that which is real. It continually takes as its task explaining the real in terms of the ideal, and this is especially true of the Idealists' philosophy of nature.' Is this a hopeless undertaking? Does Idealism not lack an empirical basis? Can one secure any solid ground whatsoever in the ether of the ideal? In what follows, I explain how, more than anyone else, Schelling and Hegel sought to handle this problem and to cope with it. By way of anticipation, a clear preference for the Hegelian philosophy of nature will emerge in what follows, a preference which may come as some surprise considering how much controversy has surrounded the significance of that view. The project of renewing a thoroughgoing philosophy of nature can meaningfully begin here. (shrink)

Robert I. Soare, Automorphisms of the Lattice of Recursively Enumerable Sets. Part I: Maximal Sets.Manuel Lerman, Robert I. Soare, $d$-Simple Sets, Small Sets, and Degree Classes.Peter Cholak, Automorphisms of the Lattice of Recursively Enumerable Sets.Leo Harrington, Robert I. Soare, The $\Delta^0_3$-Automorphism Method and Noninvariant Classes of Degrees.

First Published in 2003. Routledge is an imprint of Taylor & Francis, an informa company.

The study ties in with former considerations concerning the problem of phenomenal perception of higher animals. Accordingly the phenomenal character, qualia included, results from the adjustment of perceptions to (typal) behavioral dispositions under the principle of self-preservation: an emergence phenomenon provided by the constitutive system unity of perception and behavior, here characterized as percept-act-system. Thereby the subject of behavior can be explained as an emergent instance of the – system-theoretically highest rank – percept-act-level. In terms of the principle of self-preservation (...) it subjects all sensations to an valuation. Perception thus gaining existential sense for the subject, a psychic sense-dimension is spanned which as such does not own physical but ideal character. Accessing Hegel this is further interpreted: Accordingly the ontological basis of this view is the lawfulness of nature, understood as the ideal essence underlying it. In virtue of this – basically Hegelian-type idealistic – conception the material being of nature always encloses the possibility of the psychic, according to that ideal substratum of nature. (shrink)

Previous efforts to bring the Hegelian dialectic closer to a clarification give reason for skepticism. The question: "What is dialectic", according to Dieter Henrich, "has remained without an answer so far". Hegel's objective-idealistic program is, however, so much linked to the possibility of a dialectical logic that it is an urgent desideratum to gain clarity about the stringency of dialectical argumentation. But this is only possible on the basis of a theory of dialectic. Hegel's own reflection on methods cannot (...) be considered sufficient in this respect. It does not enable us to defend the dialectical procedure against objections or to answer questions of method. In the following, a detailed reconstruction of the dialectic of 'being' and 'nothing' in Hegel's 'Science of Logic' will reveal basic structures of dialectical argumentation. As will be shown, antinomic structures play a key role. Such a 'reconstruction', however, will not be a simple confirmation of Hegelian texts, but will always have the character of a critique. In fact, it will turn out that in comparison with Hegel's development of categories, radical revisions are to be expected. ----- Bisherige Bemühungen, das Verfahren Hegelscher Dialektik einer Klärung näherzubringen, geben Anlass zur Skepsis. Die Frage: „Was ist Dialektik?“, so Dieter Henrich, sei „bisher ohne Antwort geblieben“. Das objektiv-idealistische Programm Hegels ist indes so sehr mit der Möglichkeit einer dialektischen Logik verknüpft, daß über die Stringenz dialektischer Argumentation Klarheit zu gewinnen ein dringliches Desiderat darstellt. Das aber ist nur auf der Grundlage einer Theorie der Dialektik möglich. Hegels eigene Methodenreflexion kann diesbezüglich nicht als zureichend erachtet werden. Sie versetzt uns nicht in die Lage, das dialektische Verfahren gegen Einwände zu verteidigen oder Methodenfragen zu beantworten. Im Folgenden sollen in einer detaillierten Rekonstruktion der Dialektik von ‘Sein’ und ‘Nichts’ in Hegels ‘Wissenschaft der Logik’ Grundstrukturen dialektischer Argumentation sichtbar gemacht werden. Wie gezeigt wird, kommt dabei antinomischen Strukturen eine Schlüsselfunktion zu. Eine solche 'Rekonstruktion' wird allerdings nicht eine umstandslose Bestätigung der Hegelschen Textvorlage sein können, sondern immer auch den Charakter einer Kritik haben. In der Tat wird sich ergeben, daß im Vergleich mit Hegels Kategorienentwicklung einschneidende Revisionen zu gewärtigen sind. (shrink)

From the myths of the ancient world to the Middle Ages to Darwin and beyond, Preece captures the most telling and fascinating accounts of humankind's ...

My argument is that Chalmers' zombie fiction and his rigid-designator-argument going back on Kripke comes down to a petitio principii. Rather, at the core it appears to be more related to the essential 'privacy' of the phenomenal internal perspective. In return for Chalmers I argue that the 'principle self-preservation' of living organisms necessarily implies subjectivity and the emergence of sense. The comparison with a robot proves instructive. The mode of 'mere physical' being is transcended if, in the form of phenomenal (...) perception, sense appears on the stage of higher animals – a transition explained here as an emergence phenomenon based on the systemic co-operation of perception, valuation and action ('perc-val-act system'). Some fundamental considerations are added: Those consequences implied by the principle self-preservation reveal the natural-biological origin of the organism – primarily seeming a more insignificant circumstance – as a momentous fundamental difference (end-in-itself-character, subjectivity, constitution of sense) compared to technical artefacts (robot). And the emergentist approach indicates the – maybe paradoxical – possibility of a dualism of physical and psychical phenomena in an overall physical system, that is not dualistic at the same time. (shrink)

The center of this investigation is the hard problem of phenomenal perception. To be clear, hereby it is thought of higher animals; accordingly the problem of Human consciousness will explicitly not be treated. The so-called explanatory gap (Levine), i.e. missing a neural explanation of experiences, here is emergence-theoretically countered: It is argued that systems own properties and laws different from those of their components. Applied to the brain the phenomenal character of perception is explained as an emergence effect from the (...) systemic cooperation of perception, valuation and behavior, whereby also an interpretation is opened to Davidson’s anomal monism. As is further shown, feelings are to be understood as a necessary completion of perception when, as in the case of higher animals, the behavior is primarily controlled by phenomenal perception. (shrink)

The zombie, mocking all nomological arguments, gives rise to axiological considerations that also result in a vindication of the nomological paradigm. So the ‘philosophical benefit of zombies’ ultimately proves to be that they lead to an understanding they were originally invented to refute.

Construed broadly as interpretation theory, hermeneutics could be understood to encompass all modes of interpretation (textual or otherwise), including any kind of literary criticism, from Aristotle's poetics to the New Criticism of the 1950s, as well as the French tradition of structuralism and even perhaps Derridean poststructural thought. Although Gadamer and Ricoeur both recognize the poetic work or, at least, lyric poetry, as belonging to a special class of literature, they do display somewhat different attitudes toward it. For Gadamer, one (...) of the hallmarks of the eminent text is its un‐translatability. That is, all literary works resist translation to one degree or another, but lyric poetry defies it altogether. In Part I of Truth and Method, Gadamer lays out the history of aesthetics and takes issue with the kind of “aesthetic consciousness” that takes the work of art as an object of study. (shrink)

Ever since Saul Kripke and others developed a semantic interpretation for modal logic, 'possible worlds' has been a much debated issue in contemporary metaphysics. To propose the idea of a possible world that differs in some way from our actual world - for example a world where the grass is red or where no people exist - can help us to analyse and understand a wide range of philosophical concepts, such as counterfactuals, properties, modality, and of course, the notions of (...) possibility and necessity. This book examines the ways in which possible worlds have been used as a framework for considering problems in logic and argument analysis. The book begins with a non-technical introduction to the basic ideas of modal logic in terms of Kripke's possible worlds and then moves on to a discussion of 'possible for' and 'possible that'. The central chapters examine questions of meaning, epistemic possibility, temporal logic, metaphysics, and impossibility. Girle also investigates how the idea of a possible world can be put to use in different areas of philosophy, the problems it may raise, and the benefits that can be gained. (shrink)

Ever since Saul Kripke and others developed a semantic interpretation for modal logic, 'possible worlds' has been a much debated issue in contemporary metaphysics. To propose the idea of a possible world that differs in some way from our actual world - for example a world where the grass is red or where no people exist - can help us to analyse and understand a wide range of philosophical concepts, such as counterfactuals, properties, modality, and of course, the notions of (...) possibility and necessity. This book examines the ways in which possible worlds have been used as a framework for considering problems in logic and argument analysis. The book begins with a non-technical introduction to the basic ideas of modal logic in terms of Kripke's possible worlds and then moves on to a discussion of 'possible for' and 'possible that'. The central chapters examine questions of meaning, epistemic possibility, temporal logic, metaphysics, and impossibility. Girle also investigates how the idea of a possible world can be put to use in different areas of philosophy, the problems it may raise, and the benefits that can be gained. (shrink)

The scope of my considerations here is defined along two lines, which seem to me of essential relevance for a theory of dialectic. On the one hand, the form of negation that – as self-referring antinomical negation – gains a quasi-semantic expulsory force [Sprengkraft] and therewith a forwarding [weiterverweisenden] character; on the other hand, the notion that every logical category is defective insofar as the explicit meaning of a category does not express everything that is already implicitly presupposed for its (...) meaning. Both lines are tightly interwoven. This I would like to demonstrate with the example of the dialectic of Being and Non-Being at the beginning of the Hegelian Logic. I will first make visible the basic structures of dialectical argumentation (sections II and III) – whereby certain revisions will turn out to be necessary in comparison with Hegel’s actual argument. Thereby it proves essential that the whole apparatus of logical categories and principles must be always already available and utilized for the dialectical explication: proving dialectic as a self-explication of logic by logical means: dialectic, as it were, as the self-fulfillment of logic (sections IV–VI). (shrink)

We argue that the Soros account of reflexivity does not provide a clear-cut distinction between a social science such as economics and the physical sciences. It is pointed out that the participants who attempt to learn from refutations of conjectures in the Soros world are likely to be haunted by the Duhem–Quine problem of conjointness of hypotheses and unfocused refutation. On a more constructive note, we argue that models of inductive learning, in which participants form conjectures on the basis of (...) strictly limited information sets, can capture the basic thrust of the Soros position. The conjectures are in motion, as the participants attempt to avoid those that are systematically wrong, and there is something vague and uncertain about what can be learned from experience and refutations. The only notion of market efficiency in this world is one contingent on the strictly limited and varied information sets in play. Finally we present a mathematical model and numerical simulations that help justify the causal relationship between reflexivity and far-from-equilibrium dynamics postulated by Soros. (shrink)

In their book, Darwinism Evolving: Systems Dynamics and the Genealogy of Natural Selection, Depew and Weber (1995) argued for the need to address the relationship between self-organization and natural selection in evolutionary theory, and focused on seven “visions” for doing so. Recently, Batten et al. (2008) in a paper in this journal, entitled “Visions of evolution: self-organization proposes what natural selection disposes,” picked up the issue with the work of Depew and Weber as a starting point. While the efforts of (...) both sets of authors are to be commended, there are substantive errors in both the presentations of my work and of my work with colleagues (one of the “visions” discussed) that undermine theirs. My purpose here is to correct the errors in question, thereby removing the undermining effects and in so doing reassert the position my colleagues and I first advanced more than two decades ago, and that I still stand by and argue for today. The central points are as follows: (1) Self-organization or spontaneous ordering is a process of selection; (2) this selection process is governed by a “physical selection principle”; (3) this principle is the law of maximum entropy production; and (4) natural selection is a special case where the components are replicating. (shrink)

There are arguments for determinism. Admittedly, this is opposed by the fact of everyday experience of autonomy. In the following, it is argued for the compatibility of determinism and autonomy. Taking up considerations of Donald MacKay, a fatalistic attitude can be refuted as false. Repeatedly, attempts have been made to defend the possibility of autonomy with reference to quantum physical indeterminacy. But its statistical randomness clearly misses the meaning of autonomy. What is decisive, on the other hand, is the possibility (...) of knowledge, which opens up opportunities for planning, freedom of choice and ultimately 'self-choice'. Results of neurobiological research, especially Benjamin Libet's and more recently John-Dylan Haynes', seem to refute this: Actions are unconsciously initiated before conscious decision. But, as Libet has also shown, consciousness always has the possibility of a veto – and thus also of knowledge-driven action control. Ultimately, the idea of possible self-choice can thus become the determining condition. Only such a form of rational self-determination establishes a spiritual identity and at the same time represents the maximum of autonomy possible for human beings. (shrink)

What corresponds to the present-day ‘transcendental-pragmatic’ concept of ultimate grounding in Hegel is his claim to absoluteness of the logic. Hegel’s fundamental intuition is that of a ‘backward going grounding’ obtaining the initially unproved presuppositions, thereby ‘wrapping itself into a circle’ – the project of the self-grounding of logic, understood as the self-explication of logic by logical means. Yet this is not about one of the multiple ‘logics’ which as formal constructs cannot claim absoluteness. It is rather a fundamental logic (...) that only makes logical textures possible at all and so owns transcendental character. The non-contradiction-principle is an example for this. Es- sential is that it is ‘under-cover-effcient’ as soon as meaningful concepts are used. Self-explication of the fundamental logic then means explicating its implicit under-cover validity, in fact by means of the fundamental logic itself. As is shown this is the affair of dialectic which thereby is to be understood as ultimate grounding of the fundamental logic. This is analyzed in detail using the example of the being/non-being-dialectic. As is demonstrated each explication step generates a new implicit issue and therewith a new explication-discrepancy inducing an antinomical structure that anew forwards the explication procedure. So this is entirely determined by itself. Decisive for the ultimate grounding argumentation is that thereby an objectively verifyable procedure is found, which is apparently possible only in a Hegelian framework. In contrast the immediate evidence of a speech act claimed by the transcendental-pragmatic position has only private character, which is grounding-theoretically irrelevant. (shrink)