We become aware of our bodies interoceptively, by processing signals arising from within the body, and exteroceptively, by processing signals arising on or outside the body. Recent research highlights the importance of the interaction of exteroceptive and interoceptive signals in modulating bodily self-consciousness. The current study investigated the effect of social self-focus, manipulated via a video camera that was facing the participants and that was either switched on or off, on interoceptive sensitivity and on tactile perception ). The results indicated (...) a significant effect of self-focus on SSDT performance, but not on interoception. SSDT performance was not moderated by interoceptive sensitivity, although interoceptive sensitivity scores were positively correlated with false alarms, independently of self-focus. Together with previous research, our results suggest that self-focus may exert different effects on body perception depending on its mode . While interoception has been previously shown to be enhanced by private self-focus, the current study failed to find an effect of social self-focus on interoceptive sensitivity, instead demonstrating that social self-focus improves exteroceptive somatosensory processing. (shrink)

This paper presents an intuitive explanation about why and how Rawlsian Theory of Justice (Rawls in A theory of justice, Harvard University Press, Harvard, 1971) provides the foundations to a solution for algorithmic bias. The contribution of the paper is to discuss and show why Rawlsian ideas in their original form (e.g. the veil of ignorance, original position, and allowing inequalities that serve the worst-off) are relevant to operationalize fairness for algorithmic decision making. The paper also explains how this leads (...) to a specific MinMaxfairness solution, which addresses the basic challenges of algorithmic justice. We combine substantive elements of Rawlsian perspective with an intuitive explanation in order to provide accessible and practical insights. The goal is to propose and motivate why and how the MinMaxfairness solution derived from Rawlsian principles overcomes some of the current challenges for algorithmic bias and highlight the benefits provided when compared to other approaches. The paper presents and discusses the solution by building a bridge between the qualitative theoretical aspects and the quantitative technical approach. (shrink)

In the early 1920s, Hans Reichenbach and Kurt Lewin presented two topological accounts of time that appear to be interrelated in more than one respect. Despite their different approaches, their underlying idea is that time order is derived from specific structural properties of the world. In both works, moreover, the notion of genidentity--i.e., identity through or over time--plays a crucial role. Although it is well known that Reichenbach borrowed this notion from Kurt Lewin, not much has been written about their (...) relationship, nor about the way Lewin implemented this notion in his own work in order to ground his topology. This paper examines these two early versions of the topology of time, and follows the extent of Lewin’s influence on Reichenbach’s proposal. (shrink)

Platelets have important hemostatic functions in repairing blood vessels upon tissue injury. Cytokines, growth factors, and metabolites stored in platelet α‐granules and dense granules are released upon platelet activation and clotting. Emerging evidence indicates that such platelet‐derived signaling factors are instrumental in guiding tissue regeneration. Here, we discuss the important roles of platelet‐secreted signaling factors in skeletal muscle regeneration. Chemokines secreted by platelets in the early phase after injury are needed to recruit neutrophils to injured muscles, and impeding this early (...) step of muscle regeneration exacerbates inflammation at later stages, compromises neo‐angiogenesis and the growth of newly formed myofibers, and reduces post‐injury muscle force production. Platelets also contribute to the recruitment of pro‐regenerative stromal cells from the adipose tissue, and the platelet releasate may also regulate the metabolism and proliferation of muscle satellite cells, which sustain myogenesis. Therefore, harnessing the signaling functions of platelets and the platelet secretome may provide new avenues for promoting skeletal muscle regeneration in health and disease. (shrink)

This highly multidisciplinary collection discusses an increasingly important topic among scholars in science and technology studies: objectivity in science. It features eleven essays on scientific objectivity from a variety of perspectives, including philosophy of science, history of science, and feminist philosophy. Topics addressed in the book include the nature and value of scientific objectivity, the history of objectivity, and objectivity in scientific journals and communities. Taken individually, the essays supply new methodological tools for theorizing what is valuable in the pursuit (...) of objective knowledge and for investigating its history. The essays offer many starting points, while suggesting new avenues of research. Taken collectively, the essays exemplify the very virtues of objectivity that they theorize—in reading them together, the reader can sense various anxieties about the dangerously subjective in our age and locate commonalities of concern as well as differences of approach. As a result, the volume offers an expansive vision of a research community seeking a communal understanding of its own methods and its own epistemic anxieties, struggling to enunciate the key problems of knowledge of our time and offer insight into how to overcome them. -/- (Contributors: Alex Csiszar, Scott Edgar, Peter Galison, Ian Hacking, Sandra Harding, Moira Howes, Paolo Savoia, Judy Segal, Joan Steigerwald, and Alison Wylie). (shrink)

Synaptophysin (Syp) was the first synaptic vesicle (SV) protein to be cloned. Since its discovery in 1985, it has been used by us and by many laboratories around the world as an invaluable marker to study the distribution of synapses in the brain and to uncover the basic features of the life cycle of SVs. Although single gene ablation of Syp does not lead to an overt phenotype, a large body of experimental data both in vitro and in vivo indicate (...) that Syp (alone or in association with homologous proteins) is involved in multiple, important aspects of SV exo‐endocytosis, including regulation of SNARE assembly into the fusion core complex, formation of the fusion pore initiating neurotransmitter release, activation of SV endocytosis and SV biogenesis. In this article, we summarise the main results of the studies on Syp carried out by our and other laboratories, and explain why we believe that Syp plays a major role in SV trafficking. BioEssays 26:445–453, 2004. © 2004 Wiley Periodicals, Inc. (shrink)

In recent years, Reichenbach's 1920 conception of the principles of coordination has attracted increased attention after Michael Friedman's attempt to revive Reichenbach's idea of a "relativized a priori". This paper follows the origin and development of this idea in the framework of Reichenbach's distinction between the axioms of coordination and the axioms of connection. It suggests a further differentiation among the coordinating axioms and accordingly proposes a different account of Reichenbach's "relativized a priori".

Resenha do livro Filosofia da Ancestralidade de Eduardo David de Oliveira.

Parmenides and Melissus employ different deductive styles for their different kinds of argumentation. The former’s poem flows in an interesting sequence of passages: contents foreword, methodological premises, krisis, conclusions and corollaries. The latter, however, organizes an extensive process of deduction to show the characteristics of what is. In both cases, the strength of their argument rests on their deductive form, on the syntactical level of their texts: the formal structure of their reasonings help to identify the features and logical intersections (...) of their thoughts. On the one hand, Parmenides uses modal reasoning, enforcing the employment of the principle of the excluded middle. On the other hand, Melissus radicalizes the use of modal reasoning and employs counterfactual statements in order to develop his doctrine of what is. Despite their differences, both deserve a place in the Stone Age of logic and theory of argumentation due to their common ambition to demonstrate what is. (shrink)

J’espère que tout cela sera le point de départ d’une collaboration efficace dans l’avenir, et que je me permets de souhaiter, en outre, amicale.Louis Rougier à Hans Reichenbach, 24 novembre 1931.

Evidence is accumulating that individual and environmental factors in childhood and adolescence should be considered when investigating adult health and aging-related processes. The data required for this is gathered by comprehensive long-term longitudinal studies. This article describes the protocol of the Zurich Longitudinal Studies, a set of three comprehensive cohort studies on child growth, health, and development that are currently expanding into adulthood. Between 1954 and 1961, 445 healthy infants were enrolled in the first ZLS cohort. Their physical, motor, cognitive, (...) and social development and their environment were assessed comprehensively across childhood, adolescence, and into young adulthood. In the 1970s, two further cohorts were added to the ZLS and assessed with largely matched study protocols: Between 1974 and 1979, the second ZLS cohort included 265 infants, and between 1970 and 2002, the third ZLS cohort included 327 children of participants of the first ZLS cohort. Since 2019, the participants of the three ZLS cohorts have been traced and invited to participate in a first wave of assessments in adulthood to investigate their current health and development. This article describes the ZLS study protocol and discusses opportunities, methodological and conceptual challenges, and limitations arising from a long-term longitudinal cohort recruited from a study about development in early life. In the future, the ZLS will provide data to investigate childhood antecedents of adult health outcomes and, ultimately, will help respond to the frequent call of scientists to shift the focus of aging research into the first decades of life and, thus, to take a lifespan perspective on aging. (shrink)

Italian Sounding—i. e., the Italian appearance of a product or service brand irrespective of its country of origin—represents a global market phenomenon affecting a wide range of economic sectors, particularly the agro-food sector. Although its economic impact has been repeatedly stressed from different points of view, systematic scientific knowledge regarding its social–psychological bases is lacking. Three studies carried out in three different countries address this literature gap. Different consumer groups are targeted regarding major product categories pre-selected categories, which are the (...) major Italian food goods within the specific country according to piloting. In each study, the main independent variable has been manipulated by presenting real product images, whose “Italianness” degree is effectively manipulated by the main study variable across three or four levels. Main hypotheses are tested via a survey with the specific product images administered to samples in Italy, China, and the USA. Across the three studies, results show that Made in Italy products, compared to the other ones, are advantaged in terms of the main dependent variables: reputation profile, general reputation, attitude, and willingness to pay. Moreover, Italian Sounding products are endowed with corresponding significant advantages when compared to the Generic Foreign by non-Italian samples. Results reveal the specific social–psychological profile of Italian Sounding products in terms of either weaknesses or strengths when compared to both Made in Italy products and Generic Foreign ones, differently in the eyes of Italian and non-Italian consumers across different countries. Finally, consistently across the three studies, the extent to which a food product is perceived to be Italian increases consumers' WTP for that product, and this effect is consistently mediated by the product's reputation. (shrink)

In his Scientific Representation (2008), van Fraassen argues that measuring is a form of representation. In fact, every measurement pinpoints its target in accordance with specific operational rules within an already-constructed theoretical space, in which certain conceptual interconnections can be represented. Reichenbach’s 1920 account of coordination is particularly interesting in this connection. Even though recent reassessments of this account do not do full justice to some important elements lying behind it, they do have the merit of focusing on a different (...) aspect of his early work that traditional interpretations of relativized a priori principles have unfortunately neglected in favour of a more “structural” role for coordination. In Reichenbach’s early work, however, the idea of coordination was employed not only to indicate theory-specific fundamental principles such as the ones suggested in the literature on conventional principles in science, but also to refer to more “basic” assumptions. In Reichenbach, these principles are preconditions both of the individuation of physical magnitudes and of their measurement, and, as such, they are necessary to approach the world in the first instance. This paper aims to reassess Reichenbach’s approach to coordination and to the representation of physical quantities in light of recent literature on measurement and scientific representation. (shrink)

Trata-se de investigar os tipos de tropas, tal como apresentados por Maquiavel, procurando compreender as características que destacam as tropas próprias. Feito isso, assumiremos o debate entre o que é público e o que é particular, tal como posto na Arte da Guerra, relacionando-o ao tema da guerra. Tal objetivo diz respeito à investigação anunciada por Maquiavel e que relaciona a vida civil à vida militar. Procurar-se-á mostrar a perspectiva do autor sobre o uso público da guerra tanto quanto as (...) consequências desastrosas de seu uso particular. Pretende-se, em tal percurso, evidenciar a guerra como ponto central do pensamento maquiaveliano, diretamente relacionada aos fundamentos da política, assim como o interesse de Maquiavel em pensar os problemas de seu tempo e abordá-los por uma perspectiva filosófica. A pesquisa se restringe a investigar o tema a partir do Príncipe, dos Discursos sobre a Primeira Década de Tito Lívio e da Arte da Guerra. (shrink)

Spatial representations have been considered for their high didactical efficacy, as concept maps and mind maps. Graphical and spatial representations may be seen as key elements of knowledge management and may contribute to enhancing spatial knowledge. Even if isomorphisms between the physical and the mental dimension can be controversial in the field of spatial knowledge, it is nevertheless interesting to study the role of spatial interpretation in knowledge management processes. In science education, spatial skills are actually highly required due to (...) the development of new technologies and their highly demanding spatial tasks they often work intertwined with other abilities, such as logical reasoning and verbal skills. Despite spatial knowledge being significative in the overall field of learning management, there is instead little research that shows its complex role in the comprehension of concepts in the humanistic fields, e.g. in philosophical conceptual reasoning. The Elementary Logic Theory—which underlies the philosophical maps of this Atlas—identifies at the basis of complex thinking prototypical knowledge units that may be activated in the possible collaboration between explicit and implicit thinking. In EL Theory, spatiality is considered the most suitable transition format for the hypothesized collaboration between implicit and explicit processing because it shares common aspects with both of them. The focus of EL Theory is to research particularly the role of the implicit in knowledge comprehension through spatial representations. In this Atlas, the role of Elementary Logic Theory is highlighted in shaping philosophical knowledge and comprehension of philosophical concepts and their intertwining. (shrink)

Ethics in research became a central theme regarding globalization of the scientific development, particularly when related to the socioeconomic conditions of the countries involved as partners in research protocols, production of inputs and of knowledge. The objective of this paper is to analyze the sources of information about ethics in research present at Scientific Electronic Library Online. Methodologically, this is an exploratory study was carried out by the systematic analysis of the literature available. The search engines retrieved 885 summaries, from (...) which 170 were analyzed. The first publication was dated from 1996 and it could be identified the mention to international documents about research in humans. Since 2002 there has been an increase of publications related to the gain of legitimacy of the topic in academy. As a conclusion, although the amount is not huge, the manuscripts presented great impact as they stimulated debates and produced scientific knowledge on the topic. It can be observed that ethics in research has outcome the biomedical field, being inserted in other fields of knowledge. (shrink)

This paper explores both some of the concepts John Dewey exposed while in China in the 1920’s and considers why his idea of democracy did not thrive in China. In the lectures Dewey delivered in China he focused on the strength of democracy, from the perspective of political science, social science, philosophy and education. Dewey clarified the democratic way of thinking, doing and living to the Chinese people. Of these topics, he considered the philosophy of education and social and political (...) philosophy to be the most important. Through his speeches, he underlined the importance of reflective thinking and reasoning in constructing human intelligence and lively inquiries. In the early part of the 20th century, both Dewey’s pragmatism and Marx’s communism were honored and speculated. While both Dewey and Marx promoted similar aims for human beings, that is, the creation of a society for the common good, their means were substantially different. For Dewey, such a result could only be obtained by a gradual construction of communicative social relationships; for Marx, a radical revolution was necessary to get expunge the old currently dominant parties. With regards to their relationship to working for the common good, for many Chinese, Dewey’s philosophies and ideas were unclear, overly complicated, and inefficient, while Marx pointed out a concrete destination, a clearly designed and expedient wayto implement an egalitarian society. (shrink)

Análise dos processos de formação do professor. Situa inicialmente as alternativas de constituição dos agentes do sistema político administrativo da educação do final do período imperial para focalizar as estratégias formativas adotadas pela Escola Complementar, analisando para tanto entrevistas, documentos iconográficos e escritos. A delimitação espacial do estudo é a Província de São Pedro do Rio Grande do Sul, Brasil.

Discute a instrução pública a partir de seus agentes e os processos formativos de seleção, instrução, contratação, especialização e diferenciação que ao longo do tempo constituíram o professor contribuindo para a formação do cidadão e institucionalização da educação no Rio Grande do Sul.

El presente trabajo es el resultado de mi participación en el evento de discusión de la revista Problema. Anuario de Filosofía y Teoría del Derecho, que llevó por nombre “La construcción del precedente en el Civil Law: debates, conceptos y desafíos”, en el cual participaron varios colegas con un amplio conocimiento en el tema del precedente judicial; de igual forma, ahonda en los temas de mayor debate dentro de lo referente al precedente judicial, enfocado al caso chileno. Todo ello, con (...) la finalidad de proponer algunas soluciones al respecto, así como dilucidar ciertos aspectos importantes dentro del precedente. Partiendo de conceptos tan trascendentes como la prescriptibilidad, la racionalidad y el uso argumentativo, se logra llegar a ciertas problemáticas provocadas por el mal uso de los conceptos previamente mencionados, que a su vez nos conduce al stare decisis, término que mal utilizado puede resultar en un acto contrario a la independencia interna de la cual gozan los jueces. (shrink)

J’espère que tout cela sera le point de départ d’une collaboration efficace dans l’avenir, et que je me permets de souhaiter, en outre, amicale.Louis Rougier à Hans Reichenbach, 24 novembre 1931.

The organization of the Herodotian narrative is based overall in the characterization of the despotism, however this can only mean something in Herodotus‟ work if opposed to the Greek ways of political organization and mainly in relation to democracy. However, the fact that the barbarians‟ despotism takes higher evidence in the work is enough to make the theme of tyranny dominate over the poliada organization? Could not we assume that the distinction of tyranny would not be only one way to (...) show the Greeks their own particularity? In this case, the exotic one, marvelous and the admirable one would lie in the fact that the Greeks organized a completely singular way of political organization, stranger to all the other known peoples. (shrink)

Pretende-se investigar, a partir especialmente dos primeiros capítulos dos Discursos sobre a Primeira Década de Tito Lívio, de Maquiavel, a confluência e divergência de aspectos tradicionais sobre a constituição de Roma em sua fase republicana. Para tal, recorreu-se às Histórias de Políbio e à História de Roma de Tito Lívio, tomando-as como ponto de partida do debate que foi consolidando ao longo da tradição, destacando-se o modo peculiar com que Maquiavel discute o tema.

This paper aims to study the concept of “fact of reason”, with the assistance Beck as North on the stage of transcendental philosophy, more specifically its basic Kantian approach, continuing to explore the potential of the above since the contributions of Guido de Almeida and Loparic.

The negative impact of the COVID-19 pandemic on individuals’ psychosocial functioning was widely attested during the last year. However, the extent to which individual differences are associated with adaptive and maladaptive outcomes during quarantine in Italy remains largely unexplored. Using a person-oriented approach, the present study explored the association of personality profiles, based on three broad individual dispositions and two self-efficacy beliefs in the emotional area, with adaptive and maladaptive outcomes during the first Italian lockdown. In doing so, we focused (...) also on how different age groups differently faced the pandemic. The study was conducted through an online survey from May to June 2020 and included 1341 participants living in Italy, divided into two groups: 737 young adults aged 18–35 and 604 adults aged 36–60 years old. Latent Profile Analysis identified three personality profiles: resilient, vulnerable, and moderate. A subsequent path analysis model showed that the resilient profile was positively associated with prosocial behavior as an indicator of adaptive outcome, and negatively associated with three maladaptive outcomes: interpersonal aggression, depressive symptoms, and anxiety problems. Contrarily, the vulnerable profile resulted negatively associated with prosocial behavior and positively associated with the three maladaptive outcomes. Finally, regarding age group differences, young adults belonging to the vulnerable profile showed a greater association especially with interpersonal aggression, depression, and anxiety problems, as compared to adults belonging to the same profile. Overall, the results of the present study highlighted the importance to analyze individual functioning during an isolation period by using a person-oriented approach. Findings evidenced the existence of three different profiles and subsequent path analysis revealed, especially for the vulnerable profile and young adults, a greater maladaptive consequence of the quarantine. The practical implications will be discussed. (shrink)