The complex hexaploid wheat genome offers many challenges for genomics research. Expressed sequence tags facilitate the analysis of gene-coding regions and provide a rich source of molecular markers for mapping and comparison with model organisms. The objectives of this study were to construct a high-density EST chromosome bin map of wheat homoeologous group 2 chromosomes to determine the distribution of ESTs, construct a consensus map of group 2 ESTs, investigate synteny, examine patterns of duplication, and assess the colinearity with rice (...) of ESTs assigned to the group 2 consensus bin map. A total of 2600 loci generated from 1110 ESTs were mapped to group 2 chromosomes by Southern hybridization onto wheat aneuploid chromosome and deletion stocks. A consensus map was constructed of 552 ESTs mapping to more than one group 2 chromosome. Regions of high gene density in distal bins and low gene density in proximal bins were found. Two interstitial gene-rich islands flanked by relatively gene-poor regions on both the short and long arms and having good synteny with rice were discovered. The map locations of two ESTs indicated the possible presence of a small pericentric inversion on chromosome 2B. Wheat chromosome group 2 was shown to share syntenous blocks with rice chromosomes 4 and 7. (shrink)

Background Protecting a person’s right to privacy and confidentiality is important in healthcare services. As future health professionals, nursing students should bear the same responsibility as qualified health professionals in protecting patient privacy. Objectives To investigate nursing students’ practices of patient privacy protection and to identify factors associated with their practices. Research design A cross-sectional study design was adopted. A two-part survey was used to collect two types of data on nursing students: (1) personal characteristics, including demographics, clinical experience and (...) use of information and communication technology and social media and (2) practice of patient privacy protection, collected using the Patient Privacy Scale. Participants and research context: A total of 319 nursing students aged 18 or above, studying pre-registration nursing programmes and who had attended at least one block of clinical placement, were recruited from a university in Hong Kong. Ethical considerations The study received ethical approval from the Survey and Behavioural Research Ethics Committee of the Chinese University of Hong Kong. The participants were informed of the study aim and written consent was obtained before completing the survey. Findings: The mean total score on the Patient Privacy Scale was 119.7 out of 135. Nursing students who were regular users of Instagram and those who had never taken photographs with patients and hence did not need to obtain patient consent were associated with better practices of patient privacy protection (higher total scores on the Patient Privacy Scale). Conclusions The findings improve our understanding of nursing students’ practice of patient privacy protection and the associated factors. This will inform the development and revision of current strategies to enhance nursing students’ practice of patient privacy protection, especially their use of social media. (shrink)

This paper examines Choi Myeonggil’s understanding of the Daxue, based on the “Daehakgieui” 大學記疑 and “Daehakgwangyeon” 大學管見 where Choi’s view on the Daxue is well expressed. In the “Daehakgieui” Choi questions Zhu Xi’s Daxuezhangju system as well as his interpretation of the Daxue. In addition, the “Daehakgwangyeon” conveys Choi’s unique view on the Daxue. With an aim to elucidate the particular aspects of Choi’s understanding of the Daxue, this paper analyzes these two texts focusing on (...) two main subjects: the system of the Daxue and the philosophical discussions of the Daxue. Endorsing the system of the old text version of the Daxue, Choi Myeonggil criticizes Zhu Xi’s Daxuezhangju system and justifies his criticism by advancing reasoned arguments. Choi is in line with Wang Shouren in that he accepts the system of the old text version of the Daxue; however, Wang regards the old text version as the definitive edition whereas Choi considers that it is littered with flaws. Regarding the philosophical discussions of the Daxue, this paper examines four concepts formulated in the Daxue: sangangling 三綱領, zhizhi erhou youding 知止而后有定, gewu 格物, and chengyi 誠意. Choi raises objections to Zhu’s interpretation of these four concepts, and makes his own interpretation supported by logical evidence in challenging of Zhu’s. Through the above discussion, this paper demonstrates that Choi Myeonggil gained a systematic understanding of the Daxue in an independent and critical manner. At the time of Choi, it was virtually forbidden to present one’s original idea while defying Zhu Xi’s authority. Considering this oppressive academic atmosphere of the Joseon dynasty, Choi’s interpretation of the Daxue assumes profound significance in Korean history of thought of Confucian classics. (shrink)

It strikes readers as dubious and pointless to compare Husserl and Deleuze straightforwardly on the level of philosophy or history of philosophy, for their thoughts seem to be wide apart or even opposed. Nevertheless, each of their thoughts draws a trajectory of development into one and the same kind of qualitative research, i.e., non-scientific, non-conceptual, fieldwork research trying to grasp the immediately pre-given picture of being. In this paper, I call such a qualitative research transcendental-phenomenological ‘regional studies.’ We might well (...) interpret the concept of ‘life-world’ in later Husserl as ‘region’ and, therefore, his life-world phenomenology as such ‘regional studies.’ Moreover, the concepts of ‘desire,’ ‘force,’ ‘intensity,’ ‘field of immanence’ in Deleuze serve very well to describe the workings of ‘region’ at a deeper level. Therefore, we observe that, under the heading of transcendental-phenomenological ‘regional studies,’ disparate philosophical concepts in Husserl and Deleuze are meaningfully connected and networked. As a result, our exposition of transcendental-phenomenological ‘regional studies’ subsuming Husserl and Deleuze sheds not only new light on the philosophical dialogue between the two, but also introduces a radically new qualitative research on region, regional life and culture. (shrink)

Previous research has shed light on the detrimental effects of abusive supervision. To extend this area of research, we draw upon conservation of resources theory to propose a causal relationship between abusive supervision and psychological distress, a mediating role of psychological distress on the relationship between abusive supervision and employee silence, and a moderating effect of the supervisor–subordinate relational context on the mediating effect of abusive supervision on silence. Through an experimental study, we found the causal path linking abusive supervision (...) and psychological distress. Results of both the experimental study and a field study provided evidence that psychological distress mediated the relationship between abusive supervision and silence. Lastly, we found support that this mediation effect was contingent upon the relational context in Study 2 but not in Study 1. We discuss implications for theory and practice. (shrink)

In this essay, I argue that in Mengzi 2A2 Mengzi 孟子 proposes his method for cultivating righteousness by showing that on the way of achieving yi, such topics as the unperturbed hearts, cultivating courage, Gaozi’s 告子 maxim, and the flood-like qi 氣 ultimately converge. Toward this aim, first, I argue that Mengzi’s short remark “bi you shi yan er wu zheng, xin wu wang, wu zhu zhang 必有事焉而勿正, 心勿忘, 勿助長” can be read as his maxim for achieving yi that structurally (...) parallels with the preceding maxim of Gaozi that Mengzi quoted. It tells us that neither our blind obedience to the words nor our impetuous boost of qi is helpful for achieving yi; instead we should concentrate on the heart’s moral sentiments and perform righteous actions. Second, I argue that Mengzi believes that qi is crucial in one’s proper self-cultivation. The centrality of moral sentiment in his teaching redirects our attention to qi’s positive aspects—exemplified by the flood-like qi—though qi’s impulsivity often makes it appear negative. If the four sprouts are to accompany the spontaneous movement of qi, it can be said that properly expressed qi signals the moral health of one’s heart. Moreover, I show that strong positive qi not only constitutes moral sentiment that serves as a fair standard for self-examination but also leads the will to perform moral actions without delay. (shrink)

There is debate over whether the content of an intuitive cognition is determined externally or internally in Ockham’s theory. According to the most common view, which I call the Strong Externalist Interpretation, intuitive content is wholly determined externally. Opposed to SE is the Strong Internalist Interpretation, according to which the content of an intuition is wholly determined by internal features of a cognizer. The aim of this paper is to argue against those interpretations, and to argue for a third kind (...) of interpretation which preserves interpretative advantages of SE and SI without falling into the difficulties that each faces. On this view, intuitive content is complex, and its complexity is analyzed into a mix of internalist and externalist elements. (shrink)

Manley and Wasserman criticize the conditional analysis of dispositions, arguing that whilst it invites the ‘strategy of getting specific’, this strategy creates more problems than it solves. I show that their understanding both of the phenomenon of masking and also of the strategy of getting specific is deeply defective, which wreaks havoc with their principal critique of the conditional analysis of dispositions.

Dialetheism is the view that there exists a true contradiction. This paper ventures to suggest that Priest’s argument for Dialetheism from Gödel’s theorem is unconvincing as the lesson of Gödel’s proof (or Rosser’s proof) is that any sufficiently strong theories of arithmetic cannot be both complete and consistent. In addition, a contradiction is derivable in Priest’s inconsistent and complete arithmetic. An alternative argument for Dialetheism is given by applying Gödel sentence to the inconsistent and complete theory of arithmetic. We argue, (...) however, that the alternative argument raises a circularity problem. In sum, Gödel’s and its related theorem merely show the relation between a complete and a consistent theory. A contradiction derived by the application of Gödel sentence has the value of true sentences, i.e. the both-value, only under the inconsistent models for arithmetic. Without having the assumption of inconsistency or completeness, a true contradiction is not derivable from the application of Gödel sentence. Hence, Gödel’s and its related theorem never can be a ground for Dialetheism. (shrink)

This study investigates: the changes in three major health-related factors—physical activity, non-physical-activity health behavior, and depressive symptoms, and how changes in physical activity were associated with changes in one’s depressive symptoms among young adults, middle-aged adults, and older adults while controlling non-physical-activity health behavior and sociodemographic characteristics among young, middle-aged, and older adults before and after the COVID-19 outbreak lockdown in the United States. A total of 695 participants completed an online questionnaire via MTurk, and participants were asked to recall (...) their physical activity, depressive symptoms, and non-physical-activity health behavior status in January and May of 2020. The IPAQ-SF was used to evaluate individuals’ physical activity, while the CES-D-10 was used to assess depressive symptoms. Covariates included non-physical-activity health behavior and sociodemographic factors. A Bayesian significance testing of changes was used to examine significant changes in physical activity, non-physical-activity behavior, and depressive symptoms in each age group while Bayesian regression analysis was employed to examine how the changes in physical activity were associated with respondents’ depressive symptoms while controlling for individual NHB and sociodemographic characteristics. The results showed that the participants tended to maintain their physical activity levels after the lockdown despite significant increases in sitting time among young and older adults. Decreases in moderate physical activity frequency were associated with a higher level of depressive symptoms. Although young and middle-aged cohorts experienced fewer differences in depressive symptoms compared to their counterparts in the older group, we found no significant heterogeneity effects in the relationships of interest across all age groups. Considering different influences of physical activity on depressive symptoms depending on different levels of activity and ages, more randomized clinical trials with program-based intervention studies should be conducted with different physical activity programs for different age populations. (shrink)

In this paper I will first consider Bird's cases against the conditional analysis of dispositions and defend them from Gundersen's objection. This does not mean that I believe that Bird's cases are successful. To the contrary, I take it that we can save the conditional analysis from Bird's cases by taking Lewis's two-step approach to dispositions. However, I will go on to argue that if Bird's cases are supplemented with the assumption that dispositions are intrinsic matter, they are able to (...) do what they are intended to do. (shrink)

In his paper, “On paradox without self-reference”, Neil Tennant proposed the conjecture for self-referential paradoxes that any derivation formalizing self-referential paradoxes only generates a looping reduction sequence. According to him, the derivation of the Liar paradox in natural deduction initiates a looping reduction sequence and the derivation of the Yablo's paradox generates a spiral reduction. The present paper proposes the counterexample to Tennant's conjecture for self-referential paradoxes. We shall show that there is a derivation of the Liar paradox which generates (...) a spiraling reduction procedure. Since the Liar paradox is a self-referential paradox, the result is a counterexample to his conjecture. Tennant has believed that classical reductio has no essential role to formalize paradoxes. As our counterexample applies the rule of classical reductio, he may reject the counterexample. In this sense, it will be briefly argued that classical reductio and his rules for the liar sentence share some inferential role. If classical reductio should not be used in paradoxical reasoning, neither should be his rules for the liar sentence. (shrink)

In his paper, “On paradox without self-reference”, Neil Tennant proposed the conjecture for self-referential paradoxes that any derivation formalizing self-referential paradoxes only generates a looping reduction sequence. According to him, the derivation of the Liar paradox in natural deduction initiates a looping reduction sequence and the derivation of the Yablo's paradox generates a spiral reduction. The present paper proposes the counterexample to Tennant's conjecture for self-referential paradoxes. We shall show that there is a derivation of the Liar paradox which generates (...) a spiraling reduction procedure. Since the Liar paradox is a self-referential paradox, the result is a counterexample to his conjecture. Tennant has believed that classical reductio has no essential role to formalize paradoxes. As our counterexample applies the rule of classical reductio, he may reject the counterexample. In this sense, it will be briefly argued that classical reductio and his rules for the liar sentence share some inferential role. If classical reductio should not be used in paradoxical reasoning, neither should be his rules for the liar sentence. (shrink)

Precision targeting of specific white matter bundles that traverse the subcallosal cingulate has been linked to efficacy of deep brain stimulation for treatment resistant depression. Methods to confirm optimal target engagement in this heterogenous region are now critical to establish an objective treatment protocol. As yet unexamined are the time-frequency features of the SCC evoked potential, including spectral power and phase-clustering. We examined these spectral features—evoked power and phase clustering—in a sample of TRD patients with implanted SCC stimulators. Electroencephalogram was (...) recorded during wakeful rest. Location of electrical stimulation in the SCC target region was the experimental manipulation. EEG was analyzed at the surface level with an average reference for a cluster of frontal sensors and at a time window identified by prior study. Morlet wavelets generated indices of evoked power and inter-trial phase clustering. Enhanced phase clustering at theta frequency was observed in every subject and was significantly correlated with SCC-EP magnitude, but only during left SCC stimulation. Stimulation to dorsal SCC evinced stronger phase clustering than ventral SCC. There was a weak correlation between phase clustering and white matter density. An increase in evoked delta power was also coincident with SCC-EP, but was less consistent across participants. DBS evoked time-frequency features index mm-scale changes to the location of stimulation in the SCC target region and correlate with structural characteristics implicated in treatment optimization. Results also imply a shared generative mechanism between evoked potentials evinced by electrical stimulation and evoked potentials evinced by auditory/visual stimuli and behavioral tasks. Understanding how current injection impacts downstream cortical activity is essential to building new technologies that adapt treatment parameters to individual differences in neurophysiology. (shrink)

In order to keep matters brief, I shall assume knowledge of my Mind paper and Sungho Choi’s paper printed before this brief response (Noordhof 1999; Choi 2002). Sungho Choi claims that the example I gave to motivate my formulation of the ‘actual events’ clause fails to motivate it and that the formulation, in fact, contains a redundant element, namely my appeal to supersets. I think he is right that my example doesn’t work. However, I think he is (...) wrong that the actual events clause contains a redundant element. The second case he discusses provides the motivation we need. (shrink)

Selected response items and constructed response items are often found in the same test. Conventional psychometric models for these two types of items typically focus on using the scores for correctness of the responses. Recent research suggests, however, that more information may be available from the CR items than just scores for correctness. In this study, we describe an approach in which a statistical topic model along with a diagnostic classification model was applied to a mixed item format formative test (...) of English and Language Arts. The DCM was used to estimate students’ mastery status of reading skills. These mastery statuses were then included in a topic model as covariates to predict students’ use of each of the latent topics in their written answers to a CR item. This approach enabled investigation of the effects of mastery status of reading skills on writing patterns. Results indicated that one of the skills, Integration of Knowledge and Ideas, helped detect and explain students’ writing patterns with respect to students’ use of individual topics. (shrink)

The Canadian-American biologist Edmund Vincent Cowdry played an important role in the birth and development of the science of aging, gerontology. In particular, he contributed to the growth of gerontology as a multidisciplinary scientific field in the United States during the 1930s and 1940s. With the support of the Josiah Macy, Jr. Foundation, he organized the first scientific conference on aging at Woods Hole, Massachusetts, where scientists from various fields gathered to discuss aging as a scientific research topic. He also (...) edited Problems of Ageing (1939), the first handbook on the current state of aging research, to which specialists from diverse disciplines contributed. The authors of this book eventually formed the Gerontological Society in 1945 as a multidisciplinary scientific organization, and some of its members, under Cowdry's leadership, formed the International Association of Gerontology in 1950. This article historically traces this development by focusing on Cowdry's ideas and activities. I argue that the social and economic turmoil during the Great Depression along with Cowdry's training and experience as a biologist – cytologist in particular – and as a textbook editor became an important basis of his efforts to construct gerontology in this direction. (shrink)

We empirically analyze the impact of economic uncertainty due to the COVID-19 pandemic on the trading volume of each sector in the S&P 500 index. Wavelet coherence analysis is carried out using economic policy uncertainty data and the trading volume of each sector in the S&P 500 index from July 2004 to September 2020. Furthermore, we apply multifractal detrended fluctuation analysis to the trading volume series of all sectors. The wavelet coherence analysis shows that the COVID-19 pandemic has substantially influenced (...) trading volume in all sectors. However, the impact of the pandemic is different from that during the global financial crisis in some sectors, such as information technology, consumer discretionary, and communication services. Because of the lockdown taken to suppress COVID-19, increased remote working and remote learning are the main reasons for these results. Additionally, according to the MF-DFA analysis, the trading volume of all the sectors has clear multifractal characteristics, and they are all nonpersistent. Specifically, trading volumes of the real estate and materials sector are highly correlated, whereas the trading volumes of industry and information technology sectors are comparatively less correlated. (shrink)