Firstly we consider the new results about enzymatic capabilities in the RNA. In this framework we analyse the sequence-folding duality as a precursor of the genotype/phenotype duality. We discuss then which are the evolutive potentialities and limitations for a system with the absence and the presence of a nucleic acid to proteins translator code. We study the arise of the code in the living systems as a form of deep interlooking between the logic of the machinery and its hardware, discussing (...) some problems that abstract modelization of this process implies. Finaly we propose to redefine the informational vocabulary usually employed in Molecular Biology. (shrink)

En el trabajo reconstruimos la trayectoria seguida en España por los agentes económicos extranjeros a lo largo del período 1936-1959. El primer estudio fue de Muñoz, Roldán y Serrano en 1978. En nuestros días hay más aportaciones, pues el tema es crucial para cualquier país. Analizamos los problemas con los nuevos "arreglos" legales y el liderazgo final de los Estados Unidos. Los datos de EE.UU. muestran una buena evidencia y por tanto una muy buena prueba del gran impacto de la (...) inversión directa extranjera en España durante este periodo. Por otro lado, cuestionamos la percepción convencional sobre la escasez de inversión extranjera en el país entre 1936 y 1959. Eso fue debido a dos aspectos claves, uno la necesidad y por el otro lado, la red de inversiones antes de 1936 que lo hicieron posible. (shrink)

(1991). Life as emergence: The roots of a new paradigm in theoretical biology. World Futures: Vol. 32, Creative Evolution in Nature, Mind, and Society, pp. 133-149.

Firstly we consider the new results about enzymatic capabilities in the RNA. In this framework we analyse the sequence-folding duality as a precursor of the genotype/phenotype duality. We discuss then which are the evolutive potentialities and limitations for a system with the absence and the presence of a nucleic acid to proteins translator code. We study the arise of the code in the living systems as a form of deep interlooking between the logic of the machinery and its hardware, discussing (...) some problems that abstract modelization of this process implies. Finaly we propose to redefine the informational vocabulary usually employed in Molecular Biology. (shrink)

We study the appearance of genetic information starting from a system where self-reproductive and enzymatic functions are supported by the same sort of molecules. In a first phase, the information must have arisen in the form of rate independent sequences as records of enzymatic functions. Although this stage must have played an important role in evolution, it will be shown how its evolutive capacities were blocked by the impossibility of appearance of geno/phenotype duality. Finally, a logical scheme is proposed for (...) a transition process toward a system with a code offering a simplification of the conditions required from the assumption of a maximum use of the double RNA capacity, both reproductive and enzymatic. (shrink)

La entrevista al doctor Camilo Fernández Cozman se realizó el 19 de julio de 2021, a 9 días del 28 de julio, fecha en la que se conmemora la Independencia del Perú.

Memories are mental states with a number of interesting features. One of those features seems to be their having an intentional object. After all, we commonly say that memories are about things, and that a subject represents the world in a certain way by virtue of remembering something. It is unclear, however, what sorts of entities constitute the intentional objects of memory. In particular, it is not clear whether those are mind-independent entities in the world or whether they are mental (...) entities of some kind. The purpose of this chapter is to map the different positions on this issue, and to highlight the virtues and difficulties for each of the options. In Section 2, I will specify the question of what the intentional objects of memory are by clarifying the relevant notions of memory and intentional object. In Section 3, I will motivate the significance of identifying the intentional objects of memory by exploring the relations between, on the one hand, the intentionality of memory and, on the other hand, the phenomenology and the epistemology of memory. In Section 4, I will consider two natural candidates for being the intentional objects of memory, namely, worldly entities and mental entities, and I will raise some concerns for each of the two candidates. A promising alternative will emerge, in Section 5, as preserving the virtues of the two original candidates while avoiding their difficulties. The alternative will concern a certain combination of worldly and mental entities; a combination that involves both causal and truth-making relations. I will conclude by sketching how the alternative candidate can shed some light on the phenomenological and epistemological issues raised in the third section. (shrink)

This article gives a conceptual review of the e-value, ev(H|X) – the epistemic value of hypothesis H given observations X. This statistical significance measure was developed in order to allow logically coherent and consistent tests of hypotheses, including sharp or precise hypotheses, via the Full Bayesian Significance Test (FBST). Arguments of analysis allow a full characterization of this statistical test by its logical or compositional properties, showing a mutual complementarity between results of mathematical statistics and the logical desiderata lying at (...) the foundations of this theory. (shrink)

Our memories elicit, in us, both beliefs about what the external world was like in the past, and beliefs about what our own past experience of it was like in the past. What explains the power of memories to do that? I tackle this question by offering an account of the content of our memories. According to this account, our memories are ‘token-reflexives’, in that they represent their own causal origin. My main contention will be that our memories are able (...) to provide us with evidence for the two types of beliefs due to the self-referential nature of their content. First, I will put forward a series of thought-experiments intended to raise several intuitions about the veridicality of memories. Next, I will introduce the view that memories are token-reflexives, and I will motivate it by pointing out that the view accommodates the relevant intuitions. And, then, I will return to the two types of beliefs prompted by our memories, and argue that conceiving memories as token-reflexives allows us to explain why memory has the power to elicit the two types of beliefs in us. (shrink)

We show how the Full Bayesian Significance Test (FBST) can be used as a model selection criterion. The FBST was presented by Pereira and Stern as a coherent Bayesian significance test. Key Words: Bayesian test; Evidence; Global optimization; Information; Model selection; Numerical integration; Posterior density; Precise hypothesis; Regularization. AMS: 62A15; 62F15; 62H15.

Este libro ofrece una imprescindible riqueza de perspectivas sobre el aspecto más problemático -que coincide con el menos tratado por los investigadores. de la obra de F. Nietzsche (1844-1990): la cuestión política. Nuestro reto de cara al Centenario de su muerte fue encarar lo que suele escamotearse. Y, al menos en este país, así ha sido por regla general. bien porque Nietzsche era "apolítico", otra forma más, como en el caso de otros pensadores, de situarlo universitariamente a la derecha, ángulo (...) desde el que se le importaba, ya porque, consigna progresista y transición filosófica, había que poner esta última interpretación en su sitio y demostrarle al mundo que Nietzsche había sido "utilizado erróneamente" por el totalitarismo nazi, el caso es que ya porque nos repugnaba moralmente aquella lectura, ya porque de tanto estar en favor de Nietzsche tampoco lo leíamos, cuestiones fundamentales de su obra y, por qué no decirlo, irritantes tanto para la derecho como para la izquierda, quedaron piadosamente salvadas. Y ahora ¿qué?... Los trabajos aquí presentados, nacionales e internacionales, han sido rigurosamente seleccionados. (shrink)

X. Zubiri, uno de los pensadores espanoles mas sobresalientes en el presente siglo, nos ha hecho ver que el mal se entiende como condicion de la realidad en respectividad ante el hombre, o sea, en la interaccion del hombre con las cosas reales o consigo mismo en cuanto realidad. En este sentido, el mal se entiende desde la realidad condicionada. Como se entiende que el mal surja desde la realidad? Cual es la consistencia del mal en cuanto condicion? En que (...) supera Zubiri la vision del mal como privacion del bien? El presente estudio pretende dar respuesta a tales cuestiones, considerando el planteamiento del mal segun Zubiri desde el contexto de su pensamiento filosofico. Julio Martin Castillo nacio en 1960 en las Yayas, La Vega (Rep. Dominicana). Ordenado sacerdote en 1986. Ha terminado su doctorado en Filosofia en la Pontificia Universidad Gregoriana (Roma). (shrink)

En este trabajo se analiza la tesis foucaultiana de la reducción de la filosofía a forma de conocimiento en Descartes y el consecuente abandono de la espiritualidad clásica, es decir, de la filosofía concebida como forma de vida basada en el cuidado de sí. A partir de aquí, además de observar que el propio Foucault matizará esta tesis, se demostrará que en Descartes la filosofía sigue esencialmente unida a la espiritualidad.

Se analizará una aporía inherente al giro subjetivo del último Foucault causada por el sostenimiento simultáneo de dos sentidos incompatibles de la irreductibilidad del sujeto y, por lo tanto, de su posible emancipación: en unos casos es posible hacer referencia a procesos de subjetivación externos a las formas de subjetividad generadas por el poder ; pero, en otros, los procesos de emancipación no pueden ser pensados más allá de la resistencia al poder. La hipótesis del trabajo es que la aporía (...) está producida por la gradual marginación del problema del autoconocimiento en la temática del cuidado de sí, que, como resultado, pasa a ser comprendida exclusivamente desde las prácticas cínicas. Pero reducido el autoconocimiento, también es eliminada la problemática del cuidado de sí, que sostenía la noción fuerte de la subjetividad. Se mostrará que en el Barroco literario y neoestoico español se pueden encontrar elementos para recuperarla. (shrink)

Resumo: O objeto deste ensaio é a análise crítica do posicionamento atual de Jürgen Habermas sobre o papel da religião no debate público. A partir da análise de dois textos recentes do mesmo sobre o tema, comparando-os com escritos anteriores, o ensaio aponta as mudanças na descrição habermasiana do papel da religião na esfera pública e em seu conceito de sociedade secular para sociedade pós-secular. Após a análise dos textos, uma avaliação crítica é oferecida, destacando-se os valores e alguns dos (...) limites do novo posicionamento de Habermas sobre o tema.Palavras-chave: Habermas - religião - esfera pública - secularização - sociedade pós-secular.: The object of this essay is a critical analysis of the contemporary view of Jürgen Habermas on the role of religion in public sphere. Based on a close reading of two recent papers of Habermas on the above subject-matter, the essay points to the changes in Habermas's thought on the theme and offers a comparison between that view and the preceding one. It also presents the notion of post-secular society, adopted by Habermas in order to warrant his change of opinion about the public role of religion. After the analysis of those papers, a critical evaluation is presented. (shrink)

This paper explores the ethical dilemma of conflicting loyalties found in whistleblowing. Central to this dilemma is the internal/external disclosure dichotomy; disclosure of organisational wrongdoing to an external recipient is seen as disloyal, whilst disclosure to an internal recipient is seen as loyal. Understanding how the organisation and society have dealt with these problems over the last 30 years is undertaken through an analysis of Vandekerckhove’s project, which seeks to place the normative legitimisations of whistleblowing legislation and organisational whistleblowing policies (...) within a globalisation semantic able to contain this conflict between society and the organisation. This project fails, it is argued, because of Vandekerckhove’s particular understanding of the organisation as an autopoietic system, i.e. an operationally closed system. A case is made to understand organisations as complex systems, i.e. operationally open systems. Critical Complexity theory sees the identities of systems and components as coterminous. In the context of the organisation, this means that the identities of the corporation and its corporate members arise and die together. The whistleblower’s disclosure reconfigures the organisation by forcing the organisation to open up and make its boundaries flexible, making the designation ‘internal’ or ‘external’ to the organisation, and, therefore, who qualifies as a recipient of a disclosure of wrongdoing, flexible. The organisation is restrained from retailing against the whistleblower, because its identities are coterminous. Furthermore, as the disclosure cannot be categorically defined as either internal or external, the question of whether an external disclosure can qualify as an act of organisational loyalty becomes moot. (shrink)