Philosophical discussions on causal inference in medicine are stuck in dyadic camps, each defending one kind of evidence or method rather than another as best support for causal hypotheses. Whereas Evidence Based Medicine advocates the use of Randomised Controlled Trials and systematic reviews of RCTs as gold standard, philosophers of science emphasise the importance of mechanisms and their distinctive informational contribution to causal inference and assessment. Some have suggested the adoption of a pluralistic approach to causal inference, and an inductive (...) rather than hypothetico-deductive inferential paradigm. However, these proposals deliver no clear guidelines about how such plurality of evidence sources should jointly justify hypotheses of causal associations. We here develop such guidelines by first giving a philosophical analysis of the underpinnings of Hill’s viewpoints on causality. We then put forward an evidence-amalgamation framework adopting a Bayesian net approach to model causal inference in pharmacology for the assessment of harms. Our framework accommodates a number of intuitions already expressed in the literature concerning the EBM vs. pluralist debate on causal inference, evidence hierarchies, causal holism, relevance, and reliability. (shrink)

This article sketches an idealized strategy for the identification of neural correlates of consciousness. The proposed strategy is based on a state space approach originating from the analysis of dynamical systems. The article then focuses on one constituent of consciousness, phenomenal awareness. Several rudimentary requirements for the identification of neural correlates of phenomenal awareness are suggested. These requirements are related to empirical data on selective attention, on completely intrinsic selection and on globally unconscious states. As an example, neuroscientific findings on (...) synchronized γ activity are categorized according to these requirements. (shrink)

Narrative allegory is distinguished from mythology as reality from symbol; it is, in short, the proper intermedium between person and personification. Where it is too strongly individualized, it ceases to be allegory […]. In the community of scholars of intermedia research, the above quoted citation is commonly regarded as Coleridge’s coining of the term “intermedium” or “intermediality”. However, a short glance at the discursive strategy of his argument emphasizes that his notion of “intermedium” must be closely linked to the poetics (...) and aesthetics of 19th-century romanticism. For the romantic poet, the term of “intermedium” does not point to media relations or intermedia processes but to.. (shrink)

According to the objective Bayesian approach to inductive logic, premisses inductively entail a conclusion just when every probability function with maximal entropy, from all those that satisfy the premisses, satisfies the conclusion. When premisses and conclusion are constraints on probabilities of sentences of a first-order predicate language, however, it is by no means obvious how to determine these maximal entropy functions. This paper makes progress on the problem in the following ways. Firstly, we introduce the concept of a limit in (...) entropy and show that, if the set of probability functions satisfying the premisses contains a limit in entropy, then this limit point is unique and is the maximal entropy probability function. Next, we turn to the special case in which the premisses are categorical sentences of the logical language. We show that if the uniform probability function gives the premisses positive probability, then the maximal entropy function can be found by simply conditionalising this uniform prior on the premisses. We generalise our results to demonstrate agreement between the maximal entropy approach and Jeffrey conditionalisation in the case in which there is a single premiss that specifies the probability of a sentence of the language. We show that, after learning such a premiss, certain inferences are preserved, namely inferences to inductive tautologies. Finally, we consider potential pathologies of the approach: we explore the extent to which the maximal entropy approach is invariant under permutations of the constants of the language, and we discuss some cases in which there is no maximal entropy probability function. (shrink)

In his paper "What Metaphors Mean", Donald Davidson attacks various theories of the metaphorical meaning. His radical thesis is that the metaphor has except the literal meaning no other (metaphorical or secondary) meaning. He refuses primarily the idea that the metaphor is some sort of communication-the speaker puts a hidden message in it and the recipient have to decode it. Davidson supported this negative attitude with a number of more or less conclusive arguments. I would like to discuss some of (...) them in this essay. My interpretation of Davidson's argumentation can be summed up as that the idea of the metaphorical meaning is not nonsensical, but it is unsuitable for explaining the intricate role of metaphors in our language. A positive theory of metaphor was only suggested by Davidson, but not properly elaborated. This was a task of his followers, in the first place of Richard Rorty. He emphasized, however, the causal character of a metaphorical effect, which radicalizes Davidson's account. As opposed to Rorty, Davidson shared with his predecessors an opinion that in a metaphor one thing is seen as another thing. None of the authors was able to explain this metaphorical definition of the metaphor. (shrink)

We study questionnaire responses to situations in which sacrificing one life may save many other lives. We demonstrate gender differences in moral judgments: males are more supportive of the sacrifice than females. We investigate a source of the endorsement of the sacrifice: antisocial preferences. First, we measure individual proneness to spiteful behavior, using an experimental game with monetary stakes. We demonstrate that spitefulness can be sizable—a fifth of our participants behave spitefully—but it is not associated with gender. Second, we find (...) that gender is consistently associated with responses even when we account for individual differences in the propensity to spitefulness. (shrink)

As digital media becomes more central to the lives of adolescents, it also becomes increasingly relevant for their sexual communication. Sexting as an important image-based digital medium provides opportunities for self-determined digital communication, but also carries specific risks for boundary violations. Accordingly, sexting is understood either as an everyday, or as risky and deviant behavior among adolescents. In the affectedness of boundary violations gender plays an important role. However, it is still unclear to what extent digital sexual communication restores stereotypical (...) gender roles and restrictive sexuality norms or, alternatively, enables new spaces of possibility. In this sense, current research points to a desideratum regarding adolescents’ orientations toward sexting as a practice between spaces of possibility and boundary violations. This paper discusses the possibilities, but also the risks, of intimate digital communication among adolescents. The main question is, how adolescents themselves perceive sexting practices and how they position themselves between both spaces for possibility and for the exchange of unwanted sexual content. For this purpose, orientations toward normalities and gender of students are reconstructed. To answer these questions, twelve single-sex, group discussions were carried out with students aged 16 and 17 at five different secondary schools in northern Germany. A total of 20 boys and 22 girls took part. The group discussions were structured by a narrative generating guideline. The analysis draws its methodology from the Documentary Method, regarding implicit and explicit forms of knowledge and discourse. It results in a typology of three types with different orientations. The study shows, that most of the students consider sexting to be a risky practice; only one type shows normality in the use of sexting. At the same time, some of the young people are interested in experimenting with image-based intimate digital communication. Further, gender differences in use and affectedness are also documented. In this way, orientations toward gender stereotypes “favor” both the attribution of responsibility to girls, and overlook the responsibility of students who perpetrated the boundary violation. The orientations of adolescents should be taken more into account in research as well as in educational programs for the prevention of sexual violence. (shrink)

Augmented Reality (AR) is commonly defined as a digital layer of information viewed on top of the physical world through a smartphone, tablet or eyewear. Increasingly, this understanding of AR is shifting to a dynamic framework of ‘smart things’, including wearable technology, sensors and artificial intelligence (AI), with the ability to intercede in key moments and to deliver contextual and meaningful experiences. The things that come into context are the logical next steps in an evolutionary development towards computers that are (...) better able to show empathy in relation to people: even more human-oriented, anticipative and ubiquitous. Thus, this outsourcing of meaning to empathic technologies points to one of the fundamental questions concerning the relation of human and technology – the nature of the trust that users place in technology. (shrink)

Epistemic scoring rules are the en vogue tool for justifications of the probability norm and further norms of rational belief formation. They are different in kind and application from statistical scoring rules from which they arose. In the first part of the paper I argue that statistical scoring rules, properly understood, are in principle better suited to justify the probability norm than their epistemic brethren. Furthermore, I give a justification of the probability norm applying statistical scoring rules. In the second (...) part of the paper I give a variety of justifications of norms for rational belief formation employing statistical scoring rules. Furthermore, general properties of statistical scoring rules are investigated. Epistemic scoring rules feature as a useful technical tool for constructing statistical scoring rules. (shrink)

This introductory chapter presents the reader with various ways of approaching the topic ‘Wittgenstein and the creativity of language’. It is argued that any serious account of the questions arising from this joint consideration of, on the one hand, this great genius of philosophy and, on the other, the varieties of speech, text, action and beauty which go under the heading ‘the creativity of language’ will have to appreciate the potential of both, in terms of breadth as well as depth. (...) First, the chapter points out a way of understanding Wittgenstein’s discussion of rules and rule-following in relation to meaning and normativity which, in virtue of respecting Wittgenstein’s own creativity as a writer, does not fall prey to a widespread source of misunderstanding. Next, Wittgenstein’s uses of language receive some additional attention (i.e. his use of analogies, metaphors, punctuation and other literary and rhetorical devices), before a glimpse is offered of an unravelling of the knot that is Wittgenstein and the creativity of language. The multiple interrelated threads here lead into areas of human concern ranging from the philosophy of language and logic through to ethics, aesthetics and politics. Finally, the chapter offers an overview of the contents of the book from the perspective of its editors. (shrink)

Interview of David Rozen with Jakub Mácha.

This paper presents the contributions of Alcindo Flores Cabral, professor of Chemistry at the Faculdade de Agronomia Eliseu Maciel, nowadays part of the Universidade Federal de Pelotas, to chemistry teaching. It is a contribution almost unknown to the Brazilian chemical community, although recognized as valuable by several renowned chemists abroad, like W. Hückel, G. Charlot, F. Strong, E. Fessenden and others. Cabral’s innovative helical representation is presented in connection not only with contemporary representations, but also an incursion is made into (...) the first helical systems proposed, those of Hinrichs and of Baumhauer. Some comments are made not only on Cabral’s Classificação Natural dos Elementos, published in 1946, but also about other texts he wrote for an efficient chemistry teaching. (shrink)

Este artigo apresenta a contribuição de Alcindo Flores Cabral (1907-1982) - professor de química da Faculdade de Agronomia Eliseu Maciel, hoje incorporada à Universidade Federal de Pelotas - ao ensino de química, uma contribuição quase desconhecida pela própria comunidade química brasileira, embora reconhecida como relevante por diversos químicos estrangeiros importantes, como W. Hückel, G. Charlot, F. Strong, E. Fessenden e outros. A inovadora representação helicoidal de Cabral é apresentada não só em conexão com representações contemporâneas, mas também inclui-se uma incursão (...) pelos primeiros sistemas helicoidais propostos, os de Hinrichs e de Baumhauer. Apresentam-se alguns comentários não somente sobre a Classificação natural dos elementos, publicada em 1946, mas também sobre outros textos escritos para tornar mais eficaz o ensino de química. (shrink)

O presente trabalho examina os aspectos históricos da extração do óleo de canela-sassafrás (Ocotea pretiosa Mez), rico em safrol, no Alto e Médio Vale do Itajaí, a partir de 1940, por iniciativa de Otto Grimm, no município de Rio do Sul. Apresenta-se o tema no contexto da memória química em Santa Catarina, e discutem-se os procedimentos utilizados, e principalmente os motivos que levaram tal indústria incipiente a não se converter em uma indústria de química fina. Para tanto, são apresentados alguns (...) dados pertinentes à química do safrol, indicando que tal indústria poderia ter evoluído, bem como os aspectos econômicos e sociais que, ao lado da proibição do corte da canela-sassafrás, levaram em 1990 à extinção definitiva dessa "química fina que poderia ter sido". (shrink)

Dos diferentes fatores associados a uma mudança de paradigma e, portanto, a uma revolução química, o menos discutido é o que envolve os assim chamados experimentos exemplares, mudanças radicais na metodologia de trabalho e nos procedimentos empíricos da química, mudanças e modificações estas que, no caso de uma ciência natural empírica, podem ter como consequência dados experimentais antes inacessíveis, levando, por fim, a uma nova abordagem de conceitos, hipóteses e teorias e desencadeando uma "revolução" química, um novo paradigma. Muito mais (...) do que uma revolução química, dever-se-ia optar por uma gradativa evolução química. Escolhemos três dessas situações como "exemplares": a modificação no procedimento empírico da química pneumática, com o uso da cuba pneumática contendo mercúrio; a introdução de novos métodos de extração de compostos orgânicos naturais, com a substituição do método pirogênico pelo de extração com solventes; um novo entendimento de "análise química", com a substituição da comparação de amostras tidas como autênticas pela decomposição do analito. (shrink)

The chemist Max von Pettenkofer studied with Justus von Liebig, and after leaving Giessen in 1844 did not immediately find an academic position. During the period 1844/1845 he wrote a cycle of 16 Chemical Sonnets, but published them only in 1886. The Sonnets have with few exceptions a historiographical character. We present a translation of the Sonette into Portuguese as well as commentaries about their content and their philosophical significance. We also comment rather briefly on Pettenkofer’s career as an empirical (...) chemist and later as a somewhat heterodox hygienist. (shrink)

In this essay, we aim to provide an overview of the periodic table’s origins and history, and of the elements which conspired to make it chemistry’s most recognisable icon. We pay attention to Mendeleev’s role in the development of a system for organising the elements and chemical knowledge while facilitating the teaching of chemistry. We look at how the reception of the table in different chemical communities was dependent on the local scientific, cultural and political context, but argue that its (...) eventual universal acceptance is due to its unique ability to accommodate possessed knowledge while enabling novel predictions. Furthermore, we argue that its capacity to unify apparently disconnected phenomena under a simple framework facilitates our understanding of periodicity, making the table an icon of aesthetic value, and an object of philosophical inquiry. Finally, we briefly explore the table’s iconicity throughout its representations in pop art and science fiction. (shrink)

Both Hegel and the later Wittgenstein were concerned with the problem of how to begin speculation, or the problem of beginning. I argue that despite many differences, there are surprising similarities between their thinking about the beginning. They both consider different kinds of beginnings and combine them into complex analogies. The beginning has a subjective and an objective moment. The philosophizing subject has to begin with something, with an object. For Hegel, the objective moment is pure being. For Wittgenstein, the (...) objective moment is something that cannot be doubted. As regards the subjective moment, the philosophizing subject has to decide, without any reason, to conclude her quest for the presuppositionless beginning and finally begin at the beginning. The arational moment of this decision is echoed throughout any rational thought. Any application of a (rational) rule is, ultimately, a blind decision to apply this rule. (shrink)

The topic of exemplarity has attracted considerable interest in philosophy, legal theory, literary studies and art recently. There is broad consensus that exemplary cases mediate between singular instances and general concepts or norms. The aim of this article is to provide an additional perspective on the logic of exemplarity. First, inspired by Jacques Derrida’s discussion of exemplarity, I shall argue that there is a kind of différance between (singular) examples and (general) exemplars. What an example exemplifies, the exemplarity of the (...) example, eludes any fixed identity and follows a logic of supplement. Second, I shall present the so-called logic of exemplarity. The received paraconsistent view has it that the exemplar of X is an X and, at the same time, is not an X. Inspired by Ludwig Wittgenstein’s discussion of the standard metre, I would like to present an alternative paracomplete view whereby we can say of an exemplar of X neither that it is an X nor that it is not an X. (shrink)

Over the past few years, the Virtual Organization (VO) paradigm has been emerging as an ideal solution to support collaboration among globally distributed entities (individuals and/or organizations). However, due to rapid technological and societal changes, there has also been an astonishing growth in technologies and services for mobile users. This has opened up new collaborative scenarios where the same participant can access the VO from different locations and mobility becomes a key issue for users and services. The nomadicity and mobility (...) introduces additional challenges for managing collaboration in VO environments. This paper focuses on the Identity Management challenge in a Mobile Dynamic VO environment, which is a VO that takes into account nomadicity and seamless mobility aspects as elaborated within the EU funded project Akogrimo (Access to Knowledge through the Grid in a mobile world). The resulting work is the design of the Akogrimo Identity Management system supporting the authentication and authorization process across the different administrative domains of the Mobile Dynamic VO. This design follows the service oriented approach and integrates the different perspectives: that of the network, that of the user and that of the service provider. Such an integration requires facing challenges; both from the architectural and technological viewpoints because different ‘worlds’ (i.e. network and service level) leverage different (and sometimes conflicting) approaches when addressing Identity Management. (shrink)

This volume draws connections between Wittgenstein's philosophy and the work of Saul Kripke, especially his Naming and Necessity. Saul Kripke is regarded as one of the foremost representatives of contemporary analytic philosophy. His most important contributions include the strict distinction between metaphysical and epistemological questions, the introduction of the notions of contingent a priori truth and necessary a posteriori truth and original accounts of names, descriptions, identity, necessity and realism. The chapters in this book elucidate the relevant connections between Kripke's (...) work and Wittgenstein, specifically concerning the standard meter, contingent apriori and rule-following. The contributions shed light on how Kripke's philosophical outlook was influenced by Wittgenstein, and how mainstream analytic philosophy and Wittgensteinian philosophy can fruitfully engage with one another. Kripke and Wittgenstein will be of interest to philosophers working on Wittgenstein, Kripke, and the history of analytic philosophy. (shrink)

This paper seeks to identify the common conditions which have supported nation formation in Mexico, abstract the specifics of the Purhepechan case to account for the degree of its advancement in contrast with other ethno-political movements in Mexico, and contextualize the regional trends vis-a- vis the ideological transformations at the level of the individual and the community. In our paper we will pay special attention to two extraordinary phenomena: the rise and discourse of the organiza- tion Ireta P’orheecheri - Purhepechan (...) Nation, and the celebration of the newly established ethnic- revivalist event P’orheecheri Jimbangi Uexurhini (Purhepechan New Year). Our thesis is that nation formation in Mexico is a result of economic and social modernization, democratization and the in- troduction of western liberal discourse, and changes in government indigenist policies that have been taken advantage of by indigenous political leaders. (shrink)

Robert Saudek, a Czech graphologist, journalist, diplomat, playwright, and novelist, was heavily influenced in his youth by Fritz Mauthner’s critique of language. Saudek later became a pioneer in the field of psychological graphology. In this article, I examine the impact of Mauthner’s critique on Saudek’s work and evaluate whether Saudek’s approach to graphology aligns with Mauthner’s ideas. I argue that, although Saudek’s graphology is rooted in Mauthner’s critique of experimental psychology, there remains room for further development in the field of (...) psychological graphology, centering on the analysis of language. With this in mind, I compare Saudek’s method and contemporary conceptual metaphor theory. I further suggest that Saudek’s extensive use of the autographs of well-known figures follows a method of working from examples, or specimens, which is not uncommon in the philosophy of science. Based on these findings, I propose a way of understanding Saudek’s graphology that challenges its characterization as a pseudoscience. (shrink)

This essay explores the notion of moral exemplarity, positing that our morality is underpinned by moral exemplars – paradigmatic examples of virtuous individuals or actions. Theoretical precepts of moral exemplarity are explored across historical and contemporary contexts, including the philosophies of Plato, Aristotle, Stoic and Christian ethics, and recent works of Alexandro Ferrara and Linda Zagzebski. This essay debates the necessity of moral exemplars, the intrinsic moral and epistemic exemplarity, and the distinction between categorical and hypothetical exemplarity, as well as (...) referencing the paradoxical Kantian dismissals of moral exemplarity. It critiques current accounts of moral exemplarity and proposes a transcendental explanation, culminating in an examination of the “exemplarist categorical imperative.”. (shrink)

In the sense-certainty chapter of the Phenomenology of Spirit, we find one of Hegel’s famous puns, which utilizes homophonic affinities and differences between the verb beiherspielen and the noun Beispiel. I argue that the effect of this pun is that the word Beispiel acquires, beyond its usual meaning of ‘example’ or ‘instance’, the meaning of a play of something inessential, a play in passing. After reviewing all available translations into English, I suggest that, in order to preserve this wordplay, one (...) can translate Beispiel as ‘by-play’. Furthermore, I analyse other occurrences of the word beiherspielen in the Phenomenology and elsewhere in Hegel’s texts. Next, I focus on the crucial importance of this pun for Derrida’s interpretation and critique of Hegel’s dialectic. Only for a certain loose translation of beiherspielen does Derrida’s reasoning appear plausible. I conclude with a discussion of the ideal of terminological uniformity in translating Hegel’s texts. In preserving the wordplay by translating Beispiel as ‘by-play’, one is forced to sacrifice the uniformity of translation. (shrink)

Zusammenfassung: Gegenstand der Arbeit ist das Konzept der metaphorischen Be-deutung, soweit dessen Ursprung in der analytischen Philosophie zu finden ist. In der Ein-leitung der Untersuchung werden jedoch auch ältere Theorien der Metapher vorgestellt, die aus der Perspektive der metaphorischen Bedeutung relevant sind oder als relevant be-trachtet werden können. Allen diesen Theorien liegt die Definition zugrunde, dass in der Metapher etwas als etwas anderes gesehen wird. Daher kann von einer Wahrnehmungs-metaphorik die Rede sein. Das erste Kapitel meiner Arbeit behandelt die Frage, (...) wie Metaphern in der Sprache zu erkennen sind. Es wird die Schlussfolgerung gezogen, dass eine Metapher, anstatt erkannt zu werden, vielmehr als solche akzeptiert werden muss. Im zweiten Kapitel werden zwei der bedeutsamsten zeitgenössischen Theorien der Metapher, nämlich von Max Black und Donald Davidson, erörtert und kritisch ausgewertet. Der Argumentation Davidsons zufolge muss die metaphorische Bedeutung als etwas All-gemeines verstanden werden, das nicht einer bestimmten Metapher, sondern der Metapher überhaupt zukommt. Dabei bleibt Davidson aber der Wahrnehmungs-metaphorik verhaftet, die bei ihm wie bei Black keine Erläuterung findet. Gegen Ende des zweiten Kapitels und hauptsächlich im dritten Kapitel werden drei Arten des Herangehens an die Wahrnehmungsmetaphorik vorgeschlagen: Sie kann entweder verworfen oder interpretiert oder aufgehoben werden. Die zwei letztgenannten Zugänge werden anhand der Schriften von Ludwig Wittgenstein, José Ortega y Gasset und Wallace Stevens weiter ausgearbeitet. -/- Abstract: This thesis investigates the concept of the metaphorical meaning originating in analytical philosophy. Also, in the Introduction are considered older theories of the meta-phor, which can be seen from the perspective of the metaphorical meaning. All these ac-counts are based on a definition that in the metaphor is something seen as something else. Therefore, all our understanding of the metaphor issues from a visual perception. But that’s a metaphor, too. Chapter I. examines the question, how to detect metaphors in lan-guage. It is concluded that metaphors must be accepted instead of detected. The chapter II. aims at introducing and criticizing the two nowadays prominent analytical theories of metaphor given by Max Black and Donald Davidson. The consequence of the argumenta-tion by Davidson is that the concept of the metaphorical meaning has to be applied to the metaphor as such, not to any particular one. In their theories, Davidson and Black are still likening the metaphor to the visual perception but this simile or rather metaphor remains unexplained. The final chapter III. presents three approaches how to deal with the visual perception metaphor in explanations of the metaphor: it can be rejected, interpreted or sublated. The last approaches are elaborated on the basis of writings by Ludwig Wittgen-stein, José Ortega y Gasset and Wallace Stevens. (shrink)

Conceptual Metaphor Theory makes some strong claims against so-called Classical Theory which spans the accounts of metaphors from Aristotle to Davidson. Most of these theories, because of their traditional literal-metaphorical distinction, fail to take into account the phenomenon of conceptual metaphor. I argue that the underlying mechanism for explaining metaphor bears some striking resemblances among all of these theories. A mapping between two structures is always expressed. Conceptual Metaphor Theory insists, however, that the literal-metaphorical distinction of Classical Theories is empirically (...) wrong. I claim that this criticism is based rather on terminological decisions than on empirical issues. Conceptual Metaphor Theory focusses primarily on conventional metaphors and struggles to extend its mechanism to novel metaphors, whereas Classical Theories focus on novel metaphors and struggle to extend their mechanisms to conventional metaphors. Since all of these theories study metaphors from the synchronic point of view, they are unable to take into account any semantic change. A diachronic perspective is what we need here, one which would allow us to explain the role of metaphor in semantic change and the development of language in general. (shrink)

Language meets reality by measuring it. My aim in this paper is to shed some light on Wittgenstein's metaphors of language's meeting and measuring reality. My additional aim will be to delimit to what extent or in what sense these functions of language are transcendental.