The understanding of decision-making systems has come together in recent years to form a unified theory of decision-making in the mammalian brain as arising from multiple, interacting systems (a planning system, a habit system, and a situation-recognition system). This unified decision-making system has multiple potential access points through which it can be driven to make maladaptive choices, particularly choices that entail seeking of certain drugs or behaviors. We identify 10 key vulnerabilities in the system: (1) moving away from homeostasis, (2) (...) changing allostatic set points, (3) euphorigenic signals, (4) overvaluation in the planning system, (5) incorrect search of situation-action-outcome relationships, (6) misclassification of situations, (7) overvaluation in the habit system, (8) a mismatch in the balance of the two decision systems, (9) over-fast discounting processes, and (10) changed learning rates. These vulnerabilities provide a taxonomy of potential problems with decision-making systems. Although each vulnerability can drive an agent to return to the addictive choice, each vulnerability also implies a characteristic symptomology. Different drugs, different behaviors, and different individuals are likely to access different vulnerabilities. This has implications for an individual's susceptibility to addiction and the transition to addiction, for the potential for relapse, and for the potential for treatment. (shrink)

Current fears of a “reproducibility crisis” have led researchers, sources of scientific funding, and the public to question both the efficacy and trustworthiness of science. Suggested policy changes have been focused on statistical problems, such as p-hacking, and issues of experimental design and execution. However, “reproducibility” is a broad concept that includes a number of issues. Furthermore, reproducibility failures occur even in fields such as mathematics or computer science that do not have statistical problems or issues with experimental design. Most (...) importantly, these proposed policy changes ignore a core feature of the process of scientific inquiry that occurs after reproducibility failures: the integration of conflicting observations and ideas into a coherent theory. (shrink)

In our target article, we proposed that addiction could be envisioned as misperformance of a decision-making machinery described by two systems (deliberative and habit systems). Several commentators have argued that Pavlovian learning also produces actions. We agree and note that Pavlovian action-selection will provide several additional vulnerabilities. Several commentators have suggested that addiction arises from sociological parameters. We note in our response how sociological effects can change decision-making variables to provide additional vulnerabilities. Commentators generally have agreed that our theory provides (...) a framework within which to site addiction and treatment, but additional work will be needed to determine whether our taxonomy will help identify and treat subpopulations within the addicted community. (shrink)

Redish builds on work on morality in economics, genetics, evolution, etc. and combines it with the latest research in neuroscientific decision-making to develop a coherent science of morality.

In the WebSurf task, humans forage for videos paying costs in terms of wait times on a time-limited task. A variant of the task in which demands during the wait time were manipulated revealed the role of attention in susceptibility to sunk costs. Consistent with parallel tasks in rodents, previous studies have found that humans preferred shorter delays, but waited longer for more preferred videos, suggesting that they were treating the delays economically. In an Amazon Mechanical Turk sample, we replicated (...) these predicted economic behaviors for a majority of participants. In the lab, participants showed susceptibility to sunk costs in this task, basing their decisions in part on time they have already waited, which we also observed in the subset of the mTurk sample that behaved economically. In another version of the task, we added an attention check to the wait phase of the delay. While that attention check further increased the proportion of subjects with predicted economic behaviors, it also removed the susceptibility to sunk costs. These findings have important implications for understanding how cognitive processes, such as the deployment of attention, are key to driving re-evaluation and susceptibility to sunk costs. (shrink)

Redish et al. trace vulnerabilities in habit and planning systems almost exclusively to pharmacological effects of addictive substances on underlying brain systems. As we discuss, however, these systems also can be disrupted by purely psychological factors inherent in normal decision-making and everyday behavior. A truly unified model must integrate the contribution of both sets of factors in driving addiction.

Although the mechanics of how the eye works are well understood, debate still exists as to how the complex machinery of the brain interprets neural impulses...

It is argued that Husserl was an “externalist” in at least one sense. For it is argued that Husserl held that genuinely perceptual experiences—that is to say, experiences that are of some real object in the world—differ intrinsically, essentially and as a kind from any hallucinatory experiences. There is, therefore, no neutral “content” that such perceptual experiences share with hallucinations, differing from them only over whether some additional non-psychological condition holds or not. In short, it is argued that Husserl was (...) a “disjunctivist”. In addition, it is argued that Husserl held that the individual object of any experience, perceptual or hallucinatory, is essential to and partly constitutive of that experience. The argument focuses on three aspects of Husserl’s thought: his account of intentional objects, his notion of horizon, and his account of reality. (shrink)

Absolutely no one still believes that every physical interactionconsists of material bodies bumping into each other. Those who have tried to work out a completely mechanistic physics have been unable to explain common phenomena like liquidity, gravitation and magnetism. In fact, there is great reason to doubt that such a physics could ever account for attractive forces in general.

Absolutely no one still believes that every physical interactionconsists of material bodies bumping into each other. Those who have tried to work out a completely mechanistic physics have been unable to explain common phenomena like liquidity, gravitation and magnetism. In fact, there is great reason to doubt that such a physics could ever account for attractive forces in general.

In this fascinating and inventive work, A. David Napier argues that the central assumption of immunology—that we survive through the recognition and elimination of non-self—has become a defining concept of the modern age. Tracing this immunological understanding of self and other through an incredibly diverse array of venues, from medical research to legal and military strategies and the electronic revolution, Napier shows how this defensive way of looking at the world not only destroys diversity but also eliminates the possibility (...) of truly engaging difference, thereby impoverishing our culture and foreclosing tremendous opportunities for personal growth. To illustrate these destructive consequences, Napier likens the current craze for embracing diversity and the use of politically correct speech to a cultural potluck to which we each bring different dishes, but at which no one can eat unless they abide by the same rules. Similarly, loaning money to developing nations serves as a tool both to make the peoples in those nations more like us and to maintain them in the nonthreatening status of distant dependents. To break free of the resulting downward spiral of homogenization and self-focus, Napier suggests that we instead adopt a new defining concept based on embryology, in which development and self-growth take place through a process of incorporation and transformation. In this effort he suggests that we have much to learn from non-Western peoples, such as the Balinese, whose ritual practices require them to take on the considerable risk of injecting into their selves the potential dangers of otherness—and in so doing ultimately strengthen themselves as well as their society. _The Age of Immunology,_ with its combination of philosophy, history, and cultural inquiry, will be seen as a manifesto for a new age and a new way of thinking about the world and our place in it. (shrink)

Alleged cases of simultaneous causation have played a prominent role in the critique of various accounts of explanation/causation and in the formation of alternative accounts. It is argued that none of the stated cases are genuine instances of simultaneous causations, since they all violate the special theory of relativity (STR). The conditions a genuine case would have to meet in light of the restrictions imposed by STR are outlined.

The most recent challenge to the covering-law model of explanation charges that the fundamental explanatory laws are not true. In fact explanation and truth are alleged to pull in different directions. We hold that this gets its force from confusing issues about the truth of the laws in the explanation and the precision with which those laws can yield an exact description of the event to be explained. In defending this we look at Cartwright's major case studies and sketch an (...) amended covering-law model of explanation. (shrink)

The most recent challenge to the covering-law model of explanation (N. Cartwright, How the laws of Physics Lie) charges that the fundamental explanatory laws are not true. In fact explanation and truth are alleged to pull in different directions. We hold that this gets its force from confusing issues about the truth of the laws in the explanation and the precision with which those laws can yield an exact description of the event to be explained. In defending this we look (...) at Cartwright's major case studies and sketch an amended covering-law model of explanation. (shrink)

En Giving Reasons, Bermejo-Luque sostiene correctamente que un modelo normativo del acto de habla de la argumentación es más defendible si se basa en un objetivo interno constitutivo del acto de argumentar, que si se apoya en objetivos que que uno no necesita perseguir cuando argumenta, tal como, en su opinión, sucede con otros modelos normativos. Ella identifica correctamente argumentar con intentar justificar. Pero no está claro que haya acertado al identificar como objetivo interno de la argumentación el mostrar que (...) una afirmación de referencia es correcta sobre la base de que las razones ofrecidas en su apoyo son correctas. En primer lugar, si argumentar, tal como ella defiende, es un intento de justificar, la mejor manera de interpretarlo es como intento de justificar la acción o emoción expresada en la conclusión. En segundo lugar, es dudoso que razones y conclusiones cualificadas puedan siempre ser reconstruidas razonablemente como afirmaciones no cualificadas, y más dudoso aún que razones y conclusiones no-constatativas puedan siempre ser reconstruidas razonablemente como afirmaciones indirectas. Más dudos aún es que podamos reconstruir razones y conclusiones no-constatativas como tesis indirectas. En tercer lugar, necesita explicar y justificar su introducción de los conceptos de mostrar y corrección en su análisis del acto de argumentar. (shrink)

Comparative Neurospychology is a collection of state-of-the-art essays by some of the world's leading neuropsychologists. Taking as their starting point the assumption that the human brain shares many of its most important functional systems with its primate relatives, the authors take acomparative evolutionary approach to understanding human cognition and brain function. A wide range of subject areas are covered, including memory, visual and somatosensory perception, motor control, attention, cross-modality integration, interhemispheric transmission, and behaviouralintelligence.

A commonplace thesis of the “new philosophy of science” is the view that the testing of a given theory is not a simple comparison of the theory with nature but also requires the comparison of the theory with competing theories. More specifically the version of the intertheoretic competition thesis that shall be examined is as follows:(ITC) In addition to comparing a theory with nature, a necessary condition for the rejection of a theory is the acceptance of an alternative theory.It is (...) Thomas Kuhn’s The Structure of Scientific Revolutions that is responsible for the widespread popularity of (ITC).1,2…a scientific theory is declared invalid only if an alternative candidate is available to take its place. No process yet disclosed by the historical study of scientific development at all resembles the methodological stereotype of falsification by direct comparison with nature. …the act of judgment that leads scientists to reject a previously accepted theory is always based upon more than a comparison of that theory with the world. (shrink)

There is a widely accepted ancient principle which holds that effects must occur as soon as possible after their causes. This paper takes this principle seriously and shows that if one believes there are causal chains then one is forced to accept the view that the temporal order is discrete or that some causally related events form a dense sequence.

The covering law model of explanation has a staying power not even to be outdone by Lazarus. For at least forty years, writer after writer has tried to put it in its grave for the last time. The most recent efforts come from Nancy Cartwright (1983). Her slant is at once modern and old fashioned. It is modern in that unlike the familiar charge that the covering law model lets in too much, her charge is that it does not let (...) in enough. It is old fashioned in that the soft spot she presses is one recognized by Hempel and Oppenheim in their classical essay. (1948, p. 248).Cartwright challenges the requirement that the sentences constituting the explanans (in particular the law or laws) must be true. (shrink)

The intertheoretic competition hypothesis (the rejection of a theory not only requires the comparison of the theory with nature but also the acceptance of an alternative theory) is a dogma of contemporary philosophy of science. I first attempt to reconstruct Thomas Kuhn's argument for the view. A central exegetical claim is that his argument rests on the Duhemian Thesis. I then show that the argument is inconclusive and suggest that there are vivid historical counterexamples to the competition hypothesis.

I show that what Quine calls 'pressing from above' is an argument for indeterminacy of translation that is generated by assuming the partial interpretation view of scientific theories. Furthermore, I argue that Quine's thesis should be understood as a reductio ad absurdum of partial interpretation and/or the view that the meaning of a term determines a unique extension for the term.

The focus of the paper is the ethical issues associated with the practice of dissecting animals in lower level college biology classes. Several arguments against dissection are explored. Furthermore, the issue is examined from the point of view of the instructor's academic freedom and the point of view of a student's moral autonomy. It is argued that even though the arguments against dissection fail, it is very important to respect the moral autonomy of students who oppose the practice. Often this (...) can be accomplished in a manner that is consistent with academic freedom and good science education. (shrink)