Results for 'Cardio vascular diseases'

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  1.  28
    Study And Analysis Of Stem Cell Therapy And Its Ethical Consideration.M. Ullah, Vidyanath Chaudhary & Nurul Absar - 2012 - Bangladesh Journal of Bioethics 1 (3):22-34.
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  2.  31
    Should we force the obese to diet?S. Giordano - 2008 - Journal of Medical Ethics 34 (5):319-319.
    There are around 94 000 000 obese people in the US alone, where 30% of the population is classified as obese.1 In industrialised countries, cardio-vascular diseases, associated with obesity and lack of physical activity, are the leading causes of death.Many millions of people affected by obesity expose themselves to stroke, heart attack, atherosclerosis, type-2 diabetes, osteoarthritis and other joint problems, sleeping problems , cancer, and psychological illnesses such as depression.While both in the United States and in the (...)
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  3.  27
    Strategies for ensuring effective surveillance in post‐transplant patients: practical organization and clinical evaluation.W. Adam Jurewicz & Andrew Miles - 2004 - Journal of Evaluation in Clinical Practice 10 (1):37-56.
  4.  35
    Diagnostic Overshadowing in Psychiatric-Somatic Comorbidity: A Case for Structural Testimonial Injustice.Anke Bueter - 2021 - Erkenntnis 88 (3):1135-1155.
    People with mental illnesses have higher prevalence and mortality rates with regard to common somatic diseases and causes of death, such as cardio-vascular conditions or cancer. One factor contributing to this excess morbidity and mortality is the sub-standard level of physical healthcare offered to the mentally ill. In particular, they are often subject to diagnostic overshadowing: a tendency to attribute physical symptoms to a pre-existing diagnosis of mental illness. This might be seen as an unfortunate instance of (...)
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  5.  16
    Effect of pitch of tone-stimuli upon body resistance and cardio-vascular phenomena.L. E. Misbach - 1932 - Journal of Experimental Psychology 15 (2):167.
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  6.  9
    A survey of the growth of knowledge about certain parts of the foetal cardio-vascular apparatus, and about the foetal circulation, in Man and some other mammals. Part I: Galen to Harvey.R. C. P. F. - 1941 - Annals of Science 5 (1):57-89.
    (1941). A survey of the growth of knowledge about certain parts of the foetal cardio-vascular apparatus, and about the foetal circulation, in Man and some other mammals. Part I: Galen to Harvey. Annals of Science: Vol. 5, No. 1, pp. 57-89.
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  7. Simultaneous recording of intracardiac ecg, pressure, phonocardiogram, and hydrogen curves using only one catheter. A new method of cardio-vascular diagnosis ja kôhler.Curves Using Only One Catheter - 1968 - In Peter Koestenbaum (ed.), Proceedings. [San Jose? Calif.,: [San Jose? Calif.. pp. 313.
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  8.  44
    Depressive symptoms related to low fractional anisotropy of white matter underlying the right ventral anterior cingulate in older adults with atherosclerotic vascular disease.Kelly R. Bijanki, Joy T. Matsui, Helen S. Mayberg, Vincent A. Magnotta, Stephan Arndt, Hans J. Johnson, Peg Nopoulos, Sergio Paradiso, Laurie M. McCormick, Jess G. Fiedorowicz, Eric A. Epping & David J. Moser - 2015 - Frontiers in Human Neuroscience 9.
  9.  6
    Vascular Amputees: A Study in Disappointment.J. M. Little, Dora Petritsi-Jones & Charles Kerr - 2022 - Journal of Bioethical Inquiry 19 (1):21-24.
    Despite optimistic reports about the results of amputation for advanced vascular disease, the patient’s assessment of advantages and disadvantages is seldom acknowledged. A detailed social study of 67 amputees has revealed considerable disparity between the patient’s views and those of the medical staff. About a third of the patients are forced to retire from active work by the amputation; about three-quarters report a serious decline in their social activities; only about half are really independent with prostheses in the long (...)
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  10.  11
    Molecular biomarkers in cardio‐oncology: Where we stand and where we are heading.Panagiotis V. S. Vasileiou, Gerasimos Siasos & Vassilis G. Gorgoulis - 2022 - Bioessays 44 (6):2100234.
    Until recently, cardiotoxicity in the setting of a malignant disease was attributed solely to the detrimental effects of chemo‐ and/or radio‐therapy to the heart. On this account, the focus was on the evaluation of well‐established cardiac biomarkers for the early detection of myocardial damage. Currently, this view has been revised. Cardiotoxicity is not restricted to a single organ but instead affects the endothelium as a whole. Indeed, it has come into light that not only cancer therapy but also malignant cells (...)
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  11.  7
    Are secondary effects of bisphosphonates on the vascular system of bone contributing to increased risk for atypical femoral fractures in osteoporosis?David A. Hart - 2023 - Bioessays 45 (4):2200206.
    Osteoporosis (OP) is a bone disease which affects a number of post‐menopausal females and puts many at risk for fractures. A large number of patients are taking bisphosphonates (BPs) to treat their OP and a rare complication is the development of atypical femoral fractures (AFF). No real explanations for the mechanisms underlying the basis for development of where AFF develop while on BPs has emerged. The present hypothesis will discuss the possibility that part of the risk for an AFF is (...)
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  12.  20
    Opportunities and Challenges in Translational Research: The Development of Photodynamic Therapy and Anti-Vascular Endothelial Growth Factor Drugs.Christina Kaiser Marko & Joan W. Miller - 2021 - Journal of Law, Medicine and Ethics 49 (1):19-24.
    The development of photodynamic therapy and anti-vascular endothelial growth factor agents have revolutionized the treatment of retinal diseases, transforming the retina subspecialty by ushering in an age of pharmacological treatments for a wide range of diseases, including age-related macular degeneration.
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  13. Psychological risk factors in cardiovascular diseases.Josef Egger - 1986 - Theoretical Medicine and Bioethics 7 (3).
    Recent research has shown that psychological risk factors play an important role in the pathogenesis of cardiovascular diseases. The so-called coronary prone behaviour pattern predominates, an important part of which is the Type A behaviour pattern. This is characterized by a marked ambition, a constant feeling of being under pressure, due to latent aggression and to a striving to dominate. For cerebrovascular diseases the so-called pressured pattern as a risk factor has been found to be typical which is (...)
     
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  14.  13
    Off-label use of bevacizumab in the treatment of retinal disease: ethical implications.Landon James Rohowetz - 2019 - Journal of Medical Ethics 45 (10):668-672.
    Anti-vascular endothelial growth factor therapy has revolutionised the treatment of a variety of ophthalmic conditions and has become the first-line therapy for a range of retinal diseases. Bevacizumab, a VEGF inhibitor first approved for the treatment of colorectal cancer, has been shown to be nearly or virtually as effective and safe as other anti-VEGF therapies in the treatment of certain retinal diseases but is not approved or registered by the Food and Drug Administration or European Medicines Agency. (...)
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  15.  12
    E‐cadherin's role in development, tissue homeostasis and disease: Insights from mouse models.Marlon R. Schneider & Frank T. Kolligs - 2015 - Bioessays 37 (3):294-304.
    Recent studies uncovered critical roles of the adhesion protein E‐cadherin in health and disease. Global inactivation of Cdh1, the gene encoding E‐cadherin in mice, results in early embryonic lethality due to an inability to form the trophectodermal epithelium. To unravel E‐cadherin's functions beyond development, numerous mouse lines with tissue‐specific disruption of Cdh1 have been generated. The consequences of E‐cadherin loss showed great variability depending on the tissue in question, ranging from nearly undetectable changes to a complete loss of tissue structure (...)
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  16.  47
    Hedgehog signalling as an antagonist of ageing and its associated diseases.Monireh Dashti, Maikel P. Peppelenbosch & Farhad Rezaee - 2012 - Bioessays 34 (10):849-856.
    Hedgehog is an important morphogenic signal that directs pattern formation during embryogenesis, but its activity also remains present through adult life. It is now becoming increasingly clear that during the reproductive phase of life and beyond it continues to direct cell renewal (which is essential to combat the chronic environmental stress to which the body is constantly exposed) and counteracts vascular, osteolytic and sometimes oncological insults to the body. Conversely, down‐regulation of hedgehog signalling is associated with ageing‐related diseases (...)
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  17.  12
    Retrospective review of bone mineral metabolism management in end-stage renal disease patients wait-listed for renal transplant.A. Chavlovski, G. A. Knoll, T. Ramsay, S. Hiremath & D. L. Zimmerman - 2012 - Transplant Research and Risk Management 2012.
    Anna Chavlovski,1 Greg A Knoll,1–3 Timothy Ramsay,4 Swapnil Hiremath,1–3 Deborah L Zimmerman1–31University of Ottawa, 2Ottawa Hospital, 3Kidney Research Centre, Ottawa Hospital Research Institute, 4Ottawa Methods Centre, Ottawa, ON, CanadaBackground: In patients with end-stage renal disease, use of vitamin D and calcium-based phosphate binders have been associated with progression of vascular calcification that might have an impact on renal transplant candidacy. Our objective was to examine management of mineral metabolism in patients wait-listed for renal transplant and to determine the impact (...)
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  18.  82
    Cardiophenomenology: a refinement of neurophenomenology.Natalie Depraz & Thomas Desmidt - 2019 - Phenomenology and the Cognitive Sciences 18 (3):493-507.
    Cardiophenomenology aims at refining the neuro-phenomenological approach created by F. Varela as a new paradigm, jointly based on Husserl’s a priori dynamics of the living present and an experiment on anticipatory time-dynamics of visual motor perception. In order to do so, we will situate the paradigm of neurophenomenology at the cardio-vascular level, focusing on the emotional dynamics of lived experience and thus refining the dialogue, more precisely, the generative mutual constraints between first- and third-person analysis. In this article (...)
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  19.  74
    The burden of dementia: A medical and research perspective.Piero Antuono & Jan Beyer - 1999 - Theoretical Medicine and Bioethics 20 (1):3-13.
    Alzheimer's disease remains the most common form of dementia. Dementia symptoms vary depending on individual personality, life experience, and social and cultural influences. As dementia progresses, involvement of multi-disciplinary health care professionals is needed to manage the disease. Alzheimer research is progressing rapidly. While 5% of all Alzheimer's disease may be genetically determined, the majority is not. Susceptibility genes can reveal the risk of contracting Alzheimer's disease. Early life risk factors such as education, nutrition, and vascular disease may increase (...)
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  20.  50
    Breast cancer and metabolic syndrome linked through the plasminogen activator inhibitor‐1 cycle.Lea M. Beaulieu, Brandi R. Whitley, Theodore F. Wiesner, Sophie M. Rehault, Diane Palmieri, Abdel G. Elkahloun & Frank C. Church - 2007 - Bioessays 29 (10):1029-1038.
    Plasminogen activator inhibitor‐1 (PAI‐1) is a physiological inhibitor of urokinase (uPA), a serine protease known to promote cell migration and invasion. Intuitively, increased levels of PAI‐1 should be beneficial in downregulating uPA activity, particularly in cancer. By contrast, in vivo, increased levels of PAI‐1 are associated with a poor prognosis in breast cancer. This phenomenon is termed the “PAI‐1 paradox”. Many factors are responsible for the upregulation of PAI‐1 in the tumor microenvironment. We hypothesize that there is a breast cancer (...)
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  21.  9
    Chronic Pain in the Elderly: Mechanisms and Perspectives.Ana P. A. Dagnino & Maria M. Campos - 2022 - Frontiers in Human Neuroscience 16:736688.
    Chronic pain affects a large part of the population causing functional disability, being often associated with coexisting psychological disorders, such as depression and anxiety, besides cognitive deficits, and sleep disturbance. The world elderly population has been growing over the last decades and the negative consequences of chronic pain for these individuals represent a current clinical challenge. The main painful complaints in the elderly are related to neurodegenerative and musculoskeletal conditions, peripheral vascular diseases, arthritis, and osteoarthritis, contributing toward poorly (...)
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  22.  11
    Pathological pericyte expansion and impaired endothelial cell-pericyte communication in endothelial Rbpj deficient brain arteriovenous malformation.Samantha Selhorst, Sera Nakisli, Shruthi Kandalai, Subhodip Adhicary & Corinne M. Nielsen - 2022 - Frontiers in Human Neuroscience 16:974033.
    Pericytes, like vascular smooth muscle cells, are perivascular cells closely associated with blood vessels throughout the body. Pericytes are necessary for vascular development and homeostasis, with particularly critical roles in the brain, where they are involved in regulating cerebral blood flow and establishing the blood-brain barrier. A role for pericytes during neurovascular disease pathogenesis is less clear—while some studies associate decreased pericyte coverage with select neurovascular diseases, others suggest increased pericyte infiltration in response to hypoxia or traumatic (...)
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  23.  21
    Cartilage formation in growth plate and arteries: from physiology to pathology.D. Magne, M. Julien, C. Vinatier, F. Merhi-Soussi, P. Weiss & J. Guicheux - 2005 - Bioessays 27 (7):708-716.
    Vascular calcifications are the consequence of several pathological conditions such as atherosclerosis, diabetes, hypercholesterolemia and chronic renal insufficiency. They are associated with risks of amputation, ischemic heart disease, stroke and increased mortality. A growing body of evidence indicates that vascular smooth muscle cells (VSMCs) undergo chondrogenic commitment eventually leading to vascular calcification, by mechanisms similar to those governing ossification in the cartilage growth plate. Our knowledge of the formation of cartilage growth plate can therefore help us to (...)
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  24.  10
    GNAQ mutations drive port wine birthmark-associated Sturge-Weber syndrome: A review of pathobiology, therapies, and current models. [REVIEW]William K. Van Trigt, Kristen M. Kelly & Christopher C. W. Hughes - 2022 - Frontiers in Human Neuroscience 16:1006027.
    Port-wine birthmarks (PWBs) are caused by somatic, mosaic mutations in the G protein guanine nucleotide binding protein alpha subunit q (GNAQ) and are characterized by the formation of dilated, dysfunctional blood vessels in the dermis, eyes, and/or brain. Cutaneous PWBs can be treated by current dermatologic therapy, like laser intervention, to lighten the lesions and diminish nodules that occur in the lesion. Involvement of the eyes and/or brain can result in serious complications and this variation is termed Sturge-Weber syndrome (SWS). (...)
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  25.  44
    Human cerebral organoids and consciousness: a double-edged sword.Andrea Lavazza - 2020 - Monash Bioethics Review 38 (2):105-128.
    Human cerebral organoids (HCOs) are three-dimensional in vitro cell cultures that mimic the developmental process and organization of the developing human brain. In just a few years this technique has produced brain models that are already being used to study diseases of the nervous system and to test treatments and drugs. Currently, HCOs consist of tens of millions of cells and have a size of a few millimeters. The greatest limitation to further development is due to their lack of (...)
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  26. Pathophysiological Bases of Comorbidity in Migraine.Claudia Altamura, Ilenia Corbelli, Marina de Tommaso, Cherubino Di Lorenzo, Giorgio Di Lorenzo, Antonio Di Renzo, Massimo Filippi, Tommaso B. Jannini, Roberta Messina, Pasquale Parisi, Vincenzo Parisi, Francesco Pierelli, Innocenzo Rainero, Umberto Raucci, Elisa Rubino, Paola Sarchielli, Linxin Li, Fabrizio Vernieri, Catello Vollono & Gianluca Coppola - 2021 - Frontiers in Human Neuroscience 15.
    Despite that it is commonly accepted that migraine is a disorder of the nervous system with a prominent genetic basis, it is comorbid with a plethora of medical conditions. Several studies have found bidirectional comorbidity between migraine and different disorders including neurological, psychiatric, cardio- and cerebrovascular, gastrointestinal, metaboloendocrine, and immunological conditions. Each of these has its own genetic load and shares some common characteristics with migraine. The bidirectional mechanisms that are likely to underlie this extensive comorbidity between migraine and (...)
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  27. Status of Cacao (Theobroma cacao L.) production on its challenges and prospect in Zamboanga del Norte Province in the Philippines.Mark Patalinghug - 2022 - International Journal of Agricultural Technology 18 (3):1075-1092.
    Examining the status of cacao production, challenges, and prospects of cacao farmersin Zamboanga del Norte province were done in this study. The investigation revealed that cacaofarming was practiced by males (244 or 65.10%) and female cacao farmers (34%) who areprimarily married with secondary educational backgrounds. Most cacao farmers were theirproductive age ranging from 50-59 years old (42.93%), 40-49 years old (34.4%). However,fewer young people engaged in cacao farming aged below 40 years old (7.46%). The primaryoccupation of the respondents was farming (...)
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  28.  44
    Still Gloria: Personal Identity and Dementia.Françoise Baylis - 2017 - International Journal of Feminist Approaches to Bioethics 10 (1):210-224.
    Beverly Beckham writes in the Boston Globe in praise of Lisa Genova’s Still Alice: “You have to get this book. … I couldn’t put it down. …” After I read Still Alice, a book of fiction about an accomplished Harvard professor with early-onset Alzheimer’s disease, I too wanted to tell everyone to get this book, but not because “I couldn’t put it down.” The first time I read it, I put it down several times to cry. It was too painful (...)
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  29.  27
    Endothelial Metabolic Control of Lymphangiogenesis.Pengchun Yu, Guosheng Wu, Heon-Woo Lee & Michael Simons - 2018 - Bioessays 40 (6):1700245.
    Lymphangiogenesis is an important developmental process that is critical to regulation of fluid homeostasis, immune surveillance and response as well as pathogenesis of a number of diseases, among them cancer, inflammation, and heart failure. Specification, formation, and maturation of lymphatic blood vessels involves an interplay between a series of events orchestrated by various transcription factors that determine expression of key genes involved in lymphangiogenesis. These are traditionally thought to be under control of several key growth factors including vascular (...)
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  30.  13
    Cognitive dysfunctions associated with white matter damage due to cardiovascular burden – determinants and interpretations.Paweł Krukow - 2014 - Polish Psychological Bulletin 45 (3):334-345.
    Although considerable research has been devoted to cognitive functions deteriorating due to diseases of cardiovascular system, rather less attention has been paid to their theoretical background. Progressive vascular disorders as hypertension, atherosclerosis and carotid artery stenosis generate most of all pathological changes in the white matter, that cause specific cognitive disorder: disconnection syndromes, and disturbances in the dynamic aspect of information processing. These features made neuropsychological disorders secondary to cardiovascular diseases different than the effects of cerebral cortex (...)
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  31.  8
    Physical Activity, Sedentary Behavior, Anxiety, and Pain Among Musicians in the United Kingdom.Raluca Matei & Jane Ginsborg - 2020 - Frontiers in Psychology 11.
    Context and AimsAlthough some exercise-based interventions have been associated with lower levels of pain and performance-related musculoskeletal disorders among musicians, the evidence is still mixed. Furthermore, little is known about musicians’ general engagement in physical activity, their knowledge of PA guidelines, or the relevant training they receive on pain prevention and the sources of such training. Similarly, little is known about the relationship between PA and PRMDs and other risk factors for PRMDs.MethodsFollowing a cross-sectional correlational study design, both standardized andad (...)
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  32.  14
    VEGF once regarded as a specif ic angiogenic factor, now implicated in neur oprotein.Erik Storkebaum, Diether Lambrechts & Peter Carmeliet - 2004 - Bioessays 26 (9):943-954.
    Both blood vessels and nerves are guided to their target. Vascular endothelial growth factor (VEGF)A is a key signal in the induction of vessel growth (a process termed angiogenesis). Though initial studies, now a decade ago, indicated that VEGF is an endothelial cell‐specific factor, more recent findings revealed that VEGF also has direct effects on neural cells. Genetic studies showed that mice with reduced VEGF levels develop adult‐onset motor neuron degeneration, reminiscent of the human neurodegenerative disorder amyotrophic lateral sclerosis (...)
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  33.  24
    Confidentiality and Its Limits.Maude Laliberté, John D. Lantos & Sonia Gowda - 2011 - Hastings Center Report 41 (6):12-13.
    In lieu of an abstract, here is a brief excerpt of the content:Confidentiality and Its LimitsMaude Laliberté, John D. Lantos, and Sonia GowdaMultiple sclerosis is believed to be an autoimmune disease of the central nervous system. However, according to Italian physician Paolo Zamboni, it is related to cerebrospinal vascular insufficiency. Zamboni claims that MS can be treated by remedying this condition with venous angioplasty. This surgery is offered as treatment for MS in various countries—Poland, Bulgaria, and Costa Rica, for (...)
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  34.  7
    Sensorimotor Synchronization in Healthy Aging and Neurocognitive Disorders.Andres von Schnehen, Lise Hobeika, Dominique Huvent-Grelle & Séverine Samson - 2022 - Frontiers in Psychology 13.
    Sensorimotor synchronization, the coordination of physical actions in time with a rhythmic sequence, is a skill that is necessary not only for keeping the beat when making music, but in a wide variety of interpersonal contexts. Being able to attend to temporal regularities in the environment is a prerequisite for event prediction, which lies at the heart of many cognitive and social operations. It is therefore of value to assess and potentially stimulate SMS abilities, particularly in aging and neurocognitive disorders, (...)
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  35.  2
    A Brief History of Blood and Lymphatic Vessels.Andreas Bikfalvi - 2017 - Cham: Imprint: Springer.
    This book provides a comprehensive account of vascular biology and pathology and its significance for health and disease. It systematically and chronologically explains how we came to our current understanding of the vasculature and it's function today, and describes in an entertaining way the diverse flaws and turns in science and medicine from the past. It thereby offers a complete and well-studied history on vascular biology and medicine. The book has an easy-to-read style and is written for students (...)
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  36.  41
    How would a latent period for early breast cancer affect the benefit of screening?Leslie E. Blumenson - 1987 - Theoretical Medicine and Bioethics 2 (2):169-182.
    The ideal goal of a screening program for breast cancer is to detect the disease at a stage when it is still curable by a simple lumpectomy. This goal would be possible if the tumor had an early latent period before it was vascularized. However, even if there existed a harmless screening examination that was sensitive enough to discover the cancer at this stage the benefit to be gained from a screening program would be highly dependent on the time the (...)
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  37.  18
    Leonardo Da Vinci’s Archival of the Dermatologic Condition.Edward Hadeler - 2021 - Journal of Medical Humanities 42 (4):795-799.
    The interconnection of scientific studies and art represented by Leonardo Da Vinci’s portraiture accentuates his role in documenting and archiving dermatologic conditions. His anatomical dissections, sketches, and paintings, including portraits, were all a means to observe, portray, and understand the nuances of the human body. In two of his most discussed portraits, Ginevra de’ Benci and Elisabetta del Giocondo, the Mona Lisa, Leonardo’s execution of the exterior anatomy is so precise that he may have illustrated manifestations of disease that allow (...)
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  38.  27
    Reifying Relevance in Mild Cognitive Impairment: An Appeal for Care and Caution.Janice E. Graham & Karen Ritchie - 2006 - Philosophy, Psychiatry, and Psychology 13 (1):57-60.
    In lieu of an abstract, here is a brief excerpt of the content:Reifying Relevance in Mild Cognitive Impairment:An Appeal for Care and CautionJanice E. Graham (bio) and Karen Ritchie (bio)KeywordsAlzheimer’s disease, construction, dementia, market forces, mild cognitive impairmentWe thank the reviewers for their thoughtful comments that probe shadowy areas in our argument, and we welcome this opportunity to elucidate our position. First, we are not repudiating the natural and social facts of pathologic brain degeneration and the physical and cognitive impairments (...)
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  39.  12
    The circle of Willis revisited: Forebrain dehydration sensing facilitated by the anterior communicating artery.Matija Fenrich, Karlo Habjanovic, Josip Kajan & Marija Heffer - 2021 - Bioessays 43 (2):2000115.
    We hypothesize that threat of dehydration provided selection pressure for the evolutionary emergence and persistence of the anterior communicating artery (ACoA – the inter‐arterial connection that completes the Circle of Willis) in early amniotes.The ACoA is a hemodynamically insignificant artery, but, as we argue in this paper, its privileged position outside the blood‐brain barrier gives it a crucial sensing function for the osmolarity of the blood against the background of the rest of the brain, which efficiently protects itself from dehydration. (...)
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  40.  6
    The circle of Willis revisited: Forebrain dehydration sensing facilitated by the anterior communicating artery.Matija Fenrich, Karlo Habjanovic, Josip Kajan & Marija Heffer - 2021 - Bioessays 43 (2):2000115.
    We hypothesize that threat of dehydration provided selection pressure for the evolutionary emergence and persistence of the anterior communicating artery (ACoA – the inter‐arterial connection that completes the Circle of Willis) in early amniotes.The ACoA is a hemodynamically insignificant artery, but, as we argue in this paper, its privileged position outside the blood‐brain barrier gives it a crucial sensing function for the osmolarity of the blood against the background of the rest of the brain, which efficiently protects itself from dehydration. (...)
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  41. Cerebral blood flow autoregulation is impaired in schizophrenia.Hsiao-Lun Ku, Timothy Lane & et al - 2017 - Schizophrenia Research:xx-yy.
    Patients with schizophrenia have a higher risk of cardiovascular diseases and higher mortality from them than does the general population; however, the underlying mechanism remains unclear. Impaired cerebral autoregulation is associated with cerebrovascular diseases and their mortality. Increased or decreased cerebral blood flow in different brain regions has been reported in patients with schizophrenia, which implies impaired cerebral autoregulation. This study investigated the cerebral autoregulation in 21 patients with schizophrenia and 23 age- and sex-matched healthy controls. None of (...)
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  42. An Expert System for Arthritis Diseases Diagnosis Using SL5 Object.Hosni Qasim El-Mashharawi, Izzeddin A. Alshawwa, Mohammed Elkahlout & Samy S. Abu-Naser - 2019 - International Journal of Academic Health and Medical Research (IJAHMR) 3 (4):28-35.
    Background: Arthritis is very common but is not well understood. Actually, “arthritis” is not a single disease; it is an informal way of referring to joint pain or joint disease. There are more than 100 different types of arthritis and related conditions. People of all ages, sexes and races can and do have arthritis, and it is the leading cause of disability in America. More than 50 million adults and 300,000 children have some type of arthritis. It is most common (...)
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  43.  51
    Using the best interests standard to decide whether to test children for untreatable, late-onset genetic diseases.Loretta M. Kopelman - 2007 - Journal of Medicine and Philosophy 32 (4):375 – 394.
    A new analysis of the Best Interests Standard is given and applied to the controversy about testing children for untreatable, severe late-onset genetic diseases, such as Huntington's disease or Alzheimer's disease. A professional consensus recommends against such predictive testing, because it is not in children's best interest. Critics disagree. The Best Interests Standard can be a powerful way to resolve such disputes. This paper begins by analyzing its meaning into three necessary and jointly sufficient conditions showing it: is an (...)
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  44.  31
    Farm animal diseases in context.Ben Mepham - 2004 - Journal of Agricultural and Environmental Ethics 17 (4-5):331-340.
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  45. Strong Medicine: Creating Incentives for Pharmaceutical Research on Neglected Diseases.Michael Kremer & Rachel Glennerster - 2005 - Ethics and International Affairs 19 (3).
    The authors suggest creating a scheme that offers new incentives for research on diseases disproportionately affecting the poor, with the goal of making development of neglected disease vaccines a lucrative endeavor for pharmaceutical companies.
     
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  46.  60
    Ethical Criteria for Human Challenge Studies in Infectious Diseases: Table 1.Ben Bambery, Michael Selgelid, Charles Weijer, Julian Savulescu & Andrew J. Pollard - 2016 - Public Health Ethics 9 (1):92-103.
    Purposeful infection of healthy volunteers with a microbial pathogen seems at odds with acceptable ethical standards, but is an important contemporary research avenue used to study infectious diseases and their treatments. Generally termed ‘controlled human infection studies’, this research is particularly useful for fast tracking the development of candidate vaccines and may provide unique insight into disease pathogenesis otherwise unavailable. However, scarce bioethical literature is currently available to assist researchers and research ethics committees in negotiating the distinct issues raised (...)
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  47. 'Report on the Diseases and Physical Peculiarities of the Negro Race'.Samuel A. Cartwright - 2004 - In Arthur L. Caplan, James J. McCartney & Dominic A. Sisti (eds.), Health, Disease, and Illness: Concepts in Medicine. Georgetown University Press. pp. 28--39.
  48. Emerging Zoonotic Diseases: Should We Rethink the Animal–Human Interface?Ioannis Magouras, Victoria J. Brookes, Ferran Jori, Angela K. Martin, Dirk Udo Pfeiffer & Salome Dürr - 2020 - Frontiers in Veterinary Science 582743 (7).
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  49. Universal etiology, multifactorial diseases and the constitutive model of disease classification.Jonathan Fuller - 2018 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 67:8-15.
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    Helpful Lessons and Cautionary Tales: How Should COVID-19 Drug Development and Access Inform Approaches to Non-Pandemic Diseases?Holly Fernandez Lynch, Arthur Caplan, Patricia Furlong & Alison Bateman-House - 2021 - American Journal of Bioethics 21 (12):4-19.
    After witnessing extraordinary scientific and regulatory efforts to speed development of and access to new COVID-19 interventions, patients facing other serious diseases have begun to ask “where’s...
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