BackgroundDespite its ubiquity, it is often not clear what organizations and services mean by well-being. Visual impairment has been associated with poorer well-being and well-being has become a key outcome for support and services for adults living with VI. A shared understanding of what well-being means is therefore essential to enable assessment of well-being and cross-service provision of well-being support.ObjectivesTo provide an overview of the ways in which well-being has been conceptualized in research relating to adults living with VI.Eligibility criteriaArticles (...) were included in the review if the article discussed well-being in the context of adults living with VI, was available in English and as a full text.Data sourcesA systematic search using search terms relating to VI and well-being was conducted in EBSCOHost and Ovid.ChartingA team of three reviewers screened titles, abstracts and full-texts articles and extracted data. Ambiguous articles were referred to the research group and discussed.ResultsOf 10,662 articles identified in the search, 249 were included in the review. These referred to 38 types of well-being. The most common types were general well-being emotional well-being and psychological well-being. Most articles referred to one type only, with a maximum of 9 listed in one article. A large number of articles did not clearly define well-being. A wide range of indicators of well-being related to the domains of hedonia, mood, positive and negative affect, quality of life, mental health, eudaimonia, self/identity, health, psychological reactions to disability and health problems, functioning, social functioning and environment, were extracted, many of which were used just once.ConclusionsThere remains a lack of consensus on how well-being is conceptualized and assessed in the context of adult VI. A standardized multi-domain approach derived with input from adults with VI and practitioners working with them is required to enable comparison of findings and cross-organizational provision of support. (shrink)

Der Streit um die Prinzipien der Theorienentwicklung hat in den Jahren seit dem Erscheinen von TH. S. KUHNS "Die Struktur wissen schaftlicher Revolutionen" mannigfache und lebhafte AufSerungen pro und contra hervorgerufen. Die Gegenposition wird im wesent lichen durch die Namen POPPER und LAKATOS charakterisiert. Die Kontroverse erweist sich als eine solche zwischen synchronischer und diachronischer, zwischen systematischer und historischer Betrach tungsweise. 1st die Entwicklung der Wissenschaften, wie man es nach KUHN glauben kann, in entscheidendem MafSe aufSeren Einfliissen und Zufalligkeiten ausgesetzt, (...) oder gibt es nicht doch rationale, rein wissenschaftsimmanente Kriterien, auf Grund derer eine Entwicklung im Sinne eines Fortschrittes zu immer besseren, richtigeren und lei stungsfahigeren Theorien moglich ist? Eine wesentliche Schwierigkeit, um dabei weiterzukommen, besteht darin, dafS es keine Moglichkeit zu geben scheint, eine Theorie zu bewerten, zu entscheiden, welche von zwei Theorien "wahrscheinlicher, richtiger, besser oder leistungs fahiger" ist. Wenn es geiange, eine numerische Bewertung von Hypothesen und Theorien in dieser Richtung zu finden, so ware damit auch ein Weg gewiesen, die Entwicklung der Theorien nicht nur zu rekon struieren, sondern vielleicht auch zu lei ten. Die Bewertung einer Theorie im Sinne ihrer Richtigkeit ist bisher nicht gelungen. Wenn POPPER, insbesondere in seinen spaten Arbeiten ("Objective Knowl edge"), die Auffassung vertritt, dafS die Entwicklung der Wissen schaften im Sinne einer immer grofSeren Wahrheitsahnlichkeit von statten gehe, so ist das bei ihm ein reiner Glaube, der auf Grund seines Modells von Versuch und Irrtum postuliert wird. (shrink)

This junior/senior level text is devoted to a study of first-order logic and its role in the foundations of mathematics: What is a proof? How can a proof be justified? To what extent can a proof be made a purely mechanical procedure? How much faith can we have in a proof that is so complex that no one can follow it through in a lifetime? The first substantial answers to these questions have only been obtained in this century. The most (...) striking results are contained in Goedel's work: First, it is possible to give a simple set of rules that suffice to carry out all mathematical proofs; but, second, these rules are necessarily incomplete - it is impossible, for example, to prove all true statements of arithmetic. The book begins with an introduction to first-order logic, Goedel's theorem, and model theory. A second part covers extensions of first-order logic and limitations of the formal methods. The book covers several advanced topics, not commonly treated in introductory texts, such as Trachtenbrot's undecidability theorem. Fraissé's elementary equivalence, and Lindstroem's theorem on the maximality of first-order logic. (shrink)

Theories of decision-making and its neural substrates have long assumed the existence of two distinct and competing valuation systems, variously described as goal-directed vs. habitual, or, more recently and based on statistical arguments, as model-free vs. model-based reinforcement-learning. Though both have been shown to control choices, the cognitive abilities associated with these systems are under ongoing investigation. Here we examine the link to cognitive abilities, and find that individual differences in processing speed covary with a shift from model-free to model-based (...) choice control in the presence of above-average working memory function. This suggests shared cognitive and neural processes; provides a bridge between literatures on intelligence and valuation; and may guide the development of process models of different valuation components. Furthermore, it provides a rationale for individual differences in the tendency to deploy valuation systems, which may be important for understanding the manifold neuropsychiatric diseases associated with malfunctions of valuation. (shrink)

This contribution to the special issue is an historical account of Paulo Freire’s pedagogical and administrative praxis before his forced exile in 1964. It relies on interviews collected during a field trip in 1976, a conversation with Paulo Freire in Geneva one year later and on the secondary literature up to date. Being the head of the first Extension Service of a major Brazilian university in the early 1960s gave Freire and his collaborators the space and time to experiment with (...) the today world famous literacy method bearing his name. The concept of ‘Field of Cultural Production’ (Bourdieu) is used to elucidate better Freire and his team’s avant-gardist production within the spaces opened up by Brazil’s popular movements in the early sixties. The contribution shows how the ‘Paulo Freire System’ developed in the praxis of a cultural movement and received its academic consecration in an incremental and eclectic style. (shrink)

This collection offers a critical assessment of the published works of Piero Sraffa, one of the leading economists of the twentieth century, and their legacy for the economics profession. The topics covered explore Sraffa's interpretation of the classical economists; his theory of value and distribution; his critique of partial and general neoclassical equilibrium theory; his focus on the problem of capital; and his critique of Hayek's monetary overinvestment theory of the business cycle. Specific issues investigated include intertemporal general equilibrium theory (...) and the capital problem; the probability of reswitching; Ricardo, Malthus, and the corn model; and the meaning and implication of the capital controversy. Among the contributors are many of the world's leading students of Sraffian economics, including Nobel Laureate Paul Samuelson, Christian Bidard, Edwin Burmeister, John Eatwell, Pierangelo Garegnani, Samuel Hollander, Heinz Kurz, Lynn Mainwaring, Neri Salvadori, Bertram Schefold and Ian Steedman. (shrink)

In Thomas Thomson's System of chemistry of 1802 Bergman and Scheele are actually considered as creators of the analytical concept of an element. With regard to this, a detailed investigation of the work of Bergman and Scheele shows that Thomson's statement contains mistakes as well as inadmissable simplifications and generalizations. It is correct, however, that Bergman in 1774–1777 specifically anticipated in essential aspects the analytical element concept proposed by Lavoisier in 1787–1789.

The goal is to present how shared decision-making in paediatric oncology occurs from the viewpoints of parents and physicians. Eight Swiss Pediatric Oncology Group centres participated in this prospective study. The sample comprised a parent and physician of the minor patient. Surveys were statistically analysed by comparing physicians’ and parents’ perspectives and by evaluating factors associated with children’s actual involvement. Perspectives of ninety-one parents and twenty physicians were obtained for 151 children. Results indicate that for six aspects of information provision (...) examined, parents’ and physicians’ perceptions differed. Moreover, parents felt that the children were more competent to understand diagnosis and prognosis, assessed the disease of the children as worse, and reported higher satisfaction with decision-making on the part of the children. A patient’s age and gender predicted involvement. Older children and girls were more likely to be involved. In the decision-making process, parents held a less active role than they actually wanted. Physicians should take measures to ensure that provided information is understood correctly. Furthermore, they should work towards creating awareness for systematic differences between parents and physicians with respect to the perception of the child, the disease, and shared decision-making. (shrink)

European-Western philosophy from Plato and Aristotle to Georg Wilhelm Friedrich Hegel and Friedrich Nietzsche and to Martin Heidegger and Ludwig Wittgenstein has rightly claimed to represent a high standard. In ancient times and in the Middle Ages there were vivid exchanges with non-Western traditions, especially Egyptian and Arabic philosophies. But since the philosophy of European Enlightenment, a large part of European-Western philosophy maintains that philosophy of a high standard exists only here. This statement can be called Eurocentric and is highly (...) contestable. The clearest and strictest foundation of philosophical Eurocentrism is given by Hegel. By analyzing and criticizing his concept of philosophy in Section II, I will discuss Eurocentrism in philosophy. In Section III, I will proceed to indicate the conditions necessary to overcome it. (shrink)

Phenomenology, as we know, is the pathway of the natural consciousness towards philosophical knowledge or the pathway of the soul, which passes through the series of its forms until it becomes Spirit. It is through the most complete experience of its own self that consciousness arrives at self-knowledge qua absolute knowledge. The series of forms which consciousness passes through on its pathway - consciousness, selfconsciousness, reason, spirit - represents the extent history of the formation of consciousness in its growth to (...) the level of philosophical knowledge as a science. In this movement, the dialectical unfolding of the particular stages is at the same time the dialectical movement of the history of the experience of consciousness. Therefore, the dialectic of the particular stages in their progression is nothing but the self-movement of dialectic as history. The Hegelian notion of history is hence a dialectic of the idea, which in its movement is history. Therefore is excluded, so it seems to me, a dialectic of empirical history as such. Thus Hegel says that “the individual, so far as content is concerned, has also to go through the stages through which the general mind has passed.” This does not mean the participation of the individual in empirical history, qua empirical history, but it says that the individual’s own history is part of world history as the universal form of Spirit. This refers us to the Notion of the sense of empirical history as it is expressed in historical experience. (shrink)

This essay examines the main sources on the attitude of the Church of Cyprus in the so-called monoenergetic-monotheletic dispute. It is shown that the Church of Cyprus was a loyal and active partner in Constantinople’s policy of reconciliation with the Antichalcedonian churches of the East. Cyprus was also, especially under Archbishop Arkadios (624/25-641/2), a place of exile for opponents of this reconciliation, and in 636 also the venue of an important synod which was attended by legates of almost the whole (...) church. The resulting Ekthesis was approved also in Rome and Jerusalem. Even Maximos did not succeed, after 636, to influence the position of Arkadios through the Cypriot priest monk Marinos. His six letters to Marinos offer no evidence for a dyenergetic or dyotheletic position of the Church of Cyprus. A letter from 643, written by the successor of Arkadios, Sergios (642-655), clearly shows that there was until then no protest against the Constantinopolitan church policy in Cyprus in this time. This letter, which demonstrates the firm dyenergetic and dyotheletic position of the whole Church of Cyprus, was presented at the Lateran Synod of 649, but forged or completely rewritten for this Synod. Even after 643, there is no evidence for public dissent in the Church of Cyprus, nor should it actually be expected. (shrink)

Among the problems raised by admitting statements which are neither true nor false is the problem of how we are to cope with vague concepts. One method of dealing with such concepts has been suggested by Rosser/Turquette (1952), i.e. the employment of a many valued set theory. It is our intention in this paper to discuss the use of many valued logics, especially the set theoretical proposals of Zadeh and Brown, in dealing with this problem. Towards this end, we shall (...) pay close attention to the development of the concepts of fuzzy sets and fuzzy systems. In this regard, it will be argued that Zadeh had in mind a many valued logic where the connectives are interpreted according to Lukasiewicz and Tarski, whereas Brown's version may be based upon a Boolean-valued logic. Furthermore, we shall have occasion to distinguish between two sources of imprecision in specifying the membership of classes, i.e. conceptual vagueness and imprecision due to inexact measurement. Due to Suppes' work in this field, the latter sort of imprecision may be exemplified by providing a theory of the inexact measurement of subjective probability. Finally, we shall discuss some ways in which these two types of imprecision are intertwined. (shrink)

We propose a new way of looking at the quantum Maxwell’s demon problem in terms of conditional action. A “conditional action” on a system is a unitary time evolution, selected according to the result of a previous measurement, which can reduce the entropy of the system. However, any conditional action can be realized by an unitary time evolution of a larger system and a subsequent Lüders measurement, whereby the entropy of the entire system is either increased or remains constant. We (...) give some examples that illustrate and confirm our proposal, including the erasure of N qubits and the Szilard engine, thus relating the present approach to the Szilard principle and the Landauer principle that have been discussed as possible solutions of the Maxwell’s demon problem. (shrink)

This volume presents some discourses (or. 54, 55, 70, 71 and 72) written by the orator and philosopher Dio of Prusa (about 40 - after 111 AD), who was also called Chrysostomos ("Golden Mouth"). Of these texts there have never been detailed commentaries up to now. They draw an image of the philosopher not as an abstract thinker but as a new Odysseus, Heracles, but also as a new Socrates or Diogenes, who purposely interferes in people's affairs and by his (...) mere appearance and demeanour provokes them and prompts them to rethink and change their lives. They also outline an ideal of practical ethics to which Dio himself felt obliged; this ideal can still have an effect far beyond Dio’s times and the diverse society of the Roman Empire. (shrink)

Considered by many to be Abraham Robinson's magnum opus, this book offers an explanation of the development and applications of non-standard analysis by the mathematician who founded the subject. Non-standard analysis grew out of Robinson's attempt to resolve the contradictions posed by infinitesimals within calculus. He introduced this new subject in a seminar at Princeton in 1960, and it remains as controversial today as it was then. This paperback reprint of the 1974 revised edition is indispensable reading for anyone interested (...) in non-standard analysis. It treats in rich detail many areas of application, including topology, functions of a real variable, functions of a complex variable, and normed linear spaces, together with problems of boundary layer flow of viscous fluids and rederivations of Saint-Venant's hypothesis concerning the distribution of stresses in an elastic body. (shrink)

Toleration and respect belong to those concepts that in contemporary political debates are very frequently used, but also misused. This review article is an attempt to enter these discussions and clarify the meaning of the concepts. It is done through reference to the most advanced theory on toleration today, by the German philosopher Rainer Forst. Since his approach allows for ill-considered implications, in the final part of my article I introduce arguments that question some of them. It seems too far-reaching (...) to presuppose an ongoing process of advancement in toleration. Furthermore, one cannot argue that we have to establish a ranking in universal morality at the bottom and the particular ethicality above. Forst, however, explains toleration as a balanced conflict between universally accepted moral norms and particular ethical world-views. (shrink)

This paper examines a model in which people’s preferences adjust to changes in their relative ability to attain various goals. Preference changes are modeled as changes in the configuration of weights (or values) attached to these goals. The model permits to explain common prototype changes of preferences such as the ‘sour grapes’ or the ‘overcompensating’ phenomenon. It is found that whether the first or the second phenomenon occurs depends on whether a goal is easy or difficult to substitute by other (...) goals. If two goals are sufficiently strong substitutes for each other, no weight will be placed on that goal which is harder to attain. The results readily apply to the standard microeconomic set-up involving goods and prices, rather than abstract goals and abilities. In this case, one implication of the model is that only a subset of the overall commodity space is relevant for everyday consumer choice, which reduces the complexity of the choice procedure. The model also permits to explain how new and unfamiliar products are incorporated into the consumer’s preference pattern. (shrink)

Dans ses différentes fonctions (enseignement, édition, conseiller au Ministère de la Recherche, etc.), Heinz Wismann n’a cessé d’interroger les traditions intellectuelles qui, dans leurs différences et leurs contradictions, constituent la culture philosophique et scientifique contemporaine. D’où le titre de sa grande collection au Cerf, « Passages », en référence à Walter Benjamin, dans l’idée que la complexité du monde actuel n’est intelligible que par un décentrement rigoureux des disciplines et des traditions savantes et nationales. Depuis plus de trente ans, (...) Heinz Wismann a joué en France un rôle décisif dans la vie culturelle et intellectuelle où il s'est attaché à transmettre et à reconstruire des traditions à l'époque oubliées : les présocratiques (Héraclite), l'idéalisme allemand (Cassirer, Benjamin). Au centre de toutes ses activités de passeur entre l'Allemagne et la France, le ressort de sa démarche est une analyse des mécanismes par lesquels une tradition se sédimente et tout à la fois innove ; la conception des rapports entre les langues en est le terrain d'exercice privilégié. L'intérêt de son parcours intellectuel est indissociable de sa fréquentation de tous les milieux français (culturels, savants, politiques), dont il donne un portrait intérieur, et européens (Bulgarie, Allemagne de l'Est, etc.), où il est extrêmement connu. D’Homère à Nietszche, de Platon à Kant, de la philologie à la musique, de la langue au texte, c’est ce tissage de la pensée qu’Heinz Wismann évoque avec un savoir et un talent exceptionnels. (shrink)

Legal scholars’ interest in Shakespeare has often focused on conventional legal rules and procedures, such as those of The Merchant of Venice or Measure for Measure. Those plays certainly reveal systemic injustice, but within stable, prosperous societies, which enjoy a generally well-functioning legal order. In contrast, Shakespeare's first historical tetralogy explores the conditions for the very possibility of a legal system, in terms not unlike those described by Hobbes a half-century later. The first tetralogy's deeply collapsed, quasi-anarchic society lacks any (...) functioning legal regime. Its power politics are not, as in many of Shakespeare's other plays, merely latent, lurking beneath the patina of an otherwise functioning legal order. They pervade all of society. Dissenting from a long critical tradition, this article suggests that the figure of Henry VI does not merely represent antiquated medievalism or inept rule. Through Henry's constant recourse to legal process, arbitration and anti-militarism, the first tetralogy goes beyond questions about how to establish a functioning legal order. It examines the possibility, and meaning, of a just one. (shrink)

An exploration of Rudolf Steiner's recommendation that class teachers create verses for their pupils to be inserted into their annual school reports.

It may seem trivial to state that one of the major trends in biological investigation consists in an attempt to explain the structural and functional aspects of living matter in chemical terms, in an effort to obtain insight into the equivalent of macroscopic phenomena on the molecular level. I am sure you are aware of, and this meeting of the Association has brought ample additional evidence, in how many fields this tendency has become apparent. It can be recognized in genetics (...) with the molecular analysis of chromosomes and the enzymatic or metabolic interpretation of hereditary properties like the eyecolor of Drosophila. In a purely morphological branch like histology we do not ask merely for a differentiation of stained cell structure but we ask for the nature of the staining reaction; in nerve physiology we try to interpret conduction as alterations of protein lipoid layers; or in pathology where the age old syndrome of inflammation is explored with biochemical methods. I should mention molecular models of membranes and cell surfaces, the molecular interpretation of secretion and of the macroscopic phenomena of metabolism. Yet insofar as this yield of data could be designated as a trend, it would rather seem to be the natural outcome to be expected from the application of the analytic method of science. In one instance, however, this approach has been carried farther than in all the other fields, and it would seem to be worthwhile to pause for one moment to ask whether this case is important merely because of its technical implications or whether it is meaningful in a wider sense. (shrink)

This special issue offers a fresh re-evaluation of James Fowler's faith development theory, in celebration of his 60th birthday. Challenges to the theory have focused on the role of emotion in faith, the contributions of the psychodynamic unconscious, and the factor of the interpersonal. Now in its third decade, the theory continues to inspire theoretical and methodological reflections. The papers presented reflect the considerable influence of this theory. This issue's theme--"Religious Development Beyond the Modern Paradigm?"--was the topic of a symposium (...) held in Boston at the 107th Annual Convention of the American Psychological Association. (shrink)

Der Artikel geht der Frage nach, wie „Wir und die Anderen" in Rosenzweigs „neuem Denken" vorkommen, - und das über das Vorkommen als Thema bzw. Gegenstand hinaus im methodischen Sinne der Frage nach dem „Subjekt" dieses „neuen Denkens" selbst. Die These bezüglich dieser Frage lautet, dass Rosenzweig das Thema „Wir und die Anderen" in einer spezifischen „Dia-logik" von Verwurzelung im Eigenen und Verhältnis zum Anderen austrägt. Spezifisch ist insbesondere sein Rekurs auf die „Tatsachen" des „Welttags des Herrn", Schöpfung, Offenbarung und (...) Erlösung, als philosophische Kategorien. Durch sie wäre durchzudeklinieren, wer jeweils „Wir und die Anderen" sind. Denn im Vorgang des Stern gewinnt mit dem „Wir" ein „Subjekt" Gestalt, das den Horizont der Menschheit, des „Wir alle", gerade deshalb nicht unterbieten kann, weil es im „Gottesgeschehen" konstituiert und darin der „Weltgeschichte" ausgesetzt wird. Dass dem so ist, erfährt der Jude Rosenzweig Christen gegenüber und reflektiert er im „Stern der Erlösung" als Sprachgeschehen insbesondere in seinem Konzept „chorischen Sprechens". In diesem Artikel wird die These vermittelt durch den Umweg darüber einer Relecture unterzogen, wie Levinas Rosenzweig im „Wir" des modernen Judentums verortet.This essay is concerned with the question how Rosenzweig's „new thinking" deals with „We and the Others", - and this beyond tackling it as a topic or object but in a methodical sense as the question about the „subject" of the „new thinking" itself. Concerning this question, it is the thesis to explore that Rosenzweig ponders „We and the Others" in a specific „dia-logical" way of becoming deeply rooted in one's own while being related to the other. He specifically refers to the „facts" of the „World-Day of the Lord" as philosophical categories. They could give the cases of who it is particularly, „We and the Others": In the process of the Star a „We" becomes the „subject" which cannot deny the universal horizon of „We all" because it is constituted as such in „God's history", i.e. the temporal sequence of His World-Day, and therefore exposed to „universal world-history". That is Rosenzweig's experience as a Jew face to face with Christians which he reflects upon in the Star as a speech-process, especially in his concept of „choral speech". In this essay, the thesis is submitted to a relecture by means of a detour, which is made by following Levinas' way of locating Rosenzweig in the „We" of the modern Jewish community. (shrink)

The article attempts a reformulation of globalization theory. We identify ‘flow speak’ and the flattened ontology of the social that goes with it as a major limitation in contemporary globalization theory. Contrary to the prevailing overemphasis on mobility and deterritorialization, we suggest an existential turn that orients future globalization thinking more towards issues of belonging, choice and commitment, and the rhythmicity of social relations. To highlight the processual character of this shift of perspective, we shall draw on the paradigmatic figure (...) of the ‘homecomer’. S/he, in our understanding, embodies the ambivalence between the lure of global options and the need for commitment to lasting bonds. Thus, we do not argue for a post-mortem on globalization theory, but maintain that a deeper understanding of globalization as a ‘way of being in the world’ would require a phenomenologically inclined repositioning of the concept. (shrink)

I will return to the second point in a different context later; at this moment I will discuss only the issue raised by my pointing up the fact that the essay in question was written by someone in Professor Heller's field. What motivated me to make the statement was not my belief that the use of psychoanalysis in the interpretation of art should be restricted to certified psychoanalysts—indeed, I have always been a staunch advocate of the opposite view. My motive (...) for this, I assumed harmless, and not, of course, irrelevant, indiscretion was that I wanted to show that Professor Heller's critique of psychoanalysis was not broadly based, that his representative example was a piece that happened to have crossed his way, that he was not using the work of an established writer in the field that he was condemning. My statement that your essay is an unacceptable text in a sermon preaching against applied analysis is unrelated to the value of your article. Even if in the future it should turn out that your essay—as far as I know your first contribution to applied psychoanalysis—was the forerunner of a significant oeuvre that would put you into the class of the great contributors of psychoanalytic interpretations of literature, it is at this point not an acceptable text for a sermon against our field. Heinz Kohut, M.D., is Professorial Lecturer in Psychiatry at the University of Chicago, teacher and training analyst at the Chicago Institute for Psychoanalysis, and author of many influential works on the psychology of the self. His works include The Restoration of the Self, The Analysis of the Self: A Systematic Approach to the Psychoanalytic Treatment of Narcissistic Personality Disorders - which has appeared in German, French, and Italian translations - and a collection of his essays, Scientific Empathy and Empathic Science. His "Psychoanalysis and the Interpretation of Literature: A Correspondence with Erich Heller" was published in the Spring 1978 issue of Critical Inquiry. (shrink)

Dear Professor Heller . . . Your paper had started out superbly. It was a great aesthetic and cognitive pleasure to follow you as you guided us through the intellectual history of the main idea of Kleist's essay, from Plato through the biblical Fall of Man, to Schiller, and Kierkegaard, and Kafka. Indeed the perceptive listener's experience was so satisfying that his disappointment was doubled when he came to realize that all this erudition and beauty had been displayed only in (...) order to serve as a contrast-providing background for the sharp delineation of a reductionistic explanation which you consider to be characteristic of psychoanalysis: the interpretation of the disturbance of man's naive, unselfconscious pre-Fall state as nothing more than a portrayal of sexual impotence—the reduction of a deep existential preoccupation to a case of phimosis. I am certain that the relief I felt when you then took up Freud's demonological-neurosis paper was not an idiosyncratic response on my part but an experience shared by many open-minded listeners in your psychoanalytic audience. Let us, therefore, disregard the "text" of your sermon and consider the substantial questions that you raised after you turned to Freud; these are to my mind the most central ones that you undertook to examine in your—despite its disappointing aspects—splendid address to us. Put into my own words, your most important question was this: What is the purpose of the psychoanalyst's efforts outside the clinical setting, in particular when his contributions take the form of a pathography? That is, To what end do analysts study the psychopathology of the creators of great works? I, too, have asked myself this question, and since you read my old essay "Beyond the Bounds of the Basic Rule" , you know some of my answers. But important basic questions are hardly ever answered once and for all; and I will, therefore, under the impact of your lecture, respond as if I had heard the question for the first time. Heinz Kohut, M.D., is Professorial Lecturer in Psychiatry at the University of Chicago and a teacher and training analyst at the Chicago Institute for Psychoanalysis. His works include The Restoration of the Self, The Analysis of the Self: A Systematic Approach to the Psychoanalytic Treatment of Narcissistic Personality Disorders—which has appeared in German, French, and Italian translations—, The Restoration of the Self and collection of his essays, Scientific Empathy and Empathic Science. His "A Reply to Margret Schaefer"" was published in the Spring 1978 issue of Critical Inquiry. See also: "Psychoanalysis and the Marionette Theater: Interpretation is Not Depreciation" by Margret Schaefer in Vol. 5, No. 1. (shrink)

In the present work it will be shown that a Theory of Everything presupposes a quantization of space and time in order to uncover the law of causality as a hidden parameter of human cognition, that nature destroying comes into effect. This involves not only a re-evaluation of the reduced Planck constant, but also and above all a new interpretation of Heisenberg’s uncertainty principle as the basic description of natural behaviour. The proof is the decoding of 137.

Extensive research has demonstrated that rs1360780, a common single nucleotide polymorphism within the FKBP5 gene, interacts with early-life stress in predicting psychopathology. Previous results suggest that carriers of the TT genotype of rs1360780 who were exposed to child abuse show differences in structure and functional activation of emotion-processing brain areas belonging to the salience network. Extending these findings on intermediate phenotypes of psychopathology, we examined if the interaction between rs1360780 and child abuse predicts resting-state functional connectivity (rsFC) between the amygdala (...) and other areas of the salience network. We analyzed data of young European adults from the general population (N = 774; mean age = 18.76 years) who took part in the IMAGEN study. In the absence of main effects of genotype and abuse, a significant interaction effect was observed for rsFC between the right centromedial amygdala and right posterior insula (p <.025, FWE-corrected), which was driven by stronger rsFC in TT allele carriers with a history of abuse. Our results suggest that the TT genotype of rs1360780 may render individuals with a history of abuse more vulnerable to functional changes in communication between brain areas processing emotions and bodily sensations, which could underlie or increase the risk for psychopathology. (shrink)