Although there are various studies comparing Greek and Indian philosophy and religion, and Chinese and Western philosophy and religion, Brahman and Dao: Comparatives Studies in Indian and Chinese Philosophy and Religion is a first of its kind that brings together Indian and Chinese philosophies and religions. Brahman and Dao helps close the gap on a much needed examination on the rich history of Buddhist transmission to China, and the many generations of Indian Buddhist missionaries to China and Chinese Buddhist pilgrims (...) to India, including the legendary Bodhidharma, and Faxian and Xuanzang. (shrink)

Both decentralization of state law and cultural relativism have been fundamentally embedded in legal pluralism. As a scholarly trend in law and society, it has insightfully challenged the underpinnings of analytical positivist jurisprudence. Nevertheless, a theoretical concept of political power has significantly been missing in research on the plurality of legal practices in various jurisdictions. This Article aims to critically offer a theoretical concept of political power that takes legal decentralization and cultural relativism seriously and yet points to how and (...) where we should look into political power, assuming that legal pluralism itself may be a strategy of elites and nation-states amid globalization. First, the Article explores the contributions of legal pluralism, and its limits, in intellectually revolting against analytical positivist jurisprudence. Second, it explicates why a concept of political power has been missing, and why such a concept is required for better comprehension of legal pluralism. Third, it calls for a look into three sites of political power in the praxis of legal pluralism: politics of identities, non-ruling communities, and neo-liberal globalization. Last, the Article constructs a concept of political-legal transformations that enables us to unveil political power in the context of de-centralized legal pluralities. Power is produced in, resides in and is generated in the dynamic interactions between nation-states, localities and global agents. Transformative relations along these dimensions allow the nation-state to forfeit some elements of power, both in economics and in law, but they also enable it to maintain some essential ingredients of political power that are often veiled in the rhetoric of globalized pluralism. (shrink)

Since the 1980s the concept of ANT has remained unsettled. ANT has continuously been critiqued and hailed, ridiculed and praised. It is still an open question whether ANT should be considered a theory or a method or whether ANT is better understood as entailing the dissolution of such modern ‘‘genres’’. In this paper the authors engage with some important reflections by John Law and Bruno Latour in order to analyze what it means to ‘‘do ANT,’’ and, doing so after ‘‘doing (...) ANT on ANT.’’ In particular the authors examine two post-ANT case studies by Annemarie Mol and Marilyn Strathern and outline the notions of complexity, multiplicity, and fractality. The purpose is to illustrate the analytical consequences of thinking with post-ANT. The analysis offers insights into how it is possible to ‘‘go beyond ANT,’’ without leaving it entirely behind. (shrink)

The degradation of the majority of cellular proteins is mediated by the proteasomes. Ubiquitin‐dependent proteasomal protein degradation is executed by a number of enzymes that interact to modify the substrates prior to their engagement with the 26S proteasomes. Alternatively, certain proteins are inherently unstable and undergo “default” degradation by the 20S proteasomes. Puzzlingly, proteins are by large subjected to both degradation pathways. Proteins with unstructured regions have been found to be substrates of the 20S proteasomes in vitro and, therefore, unstructured (...) regions may serve as signals for protein degradation “by default” in the cell. The literature is loaded with examples where engagement of a protein into larger complexes increases protein stability, possibly by escaping degradation “by default”. Our model suggests that formation of protein complexes masks the unstructured regions, making them inaccessible to the 20S proteasomes. This model not only provides molecular explanations for a recent theoretical “cooperative stability” principle, but also provokes new predictions and explanations in the field of protein regulation and functionality. BioEssays 28: 844–849, 2006. © 2006 Wiley Periodicals, Inc. (shrink)

This book begins with Derrida's text, based on a lecture he gave in Montreal and is followed by two texts commenting on it. Derrida gives one of his most precise developments on the notion of 'l'événement' (event), that which comes to disturb the course of history and thus escapes the normal ways of being told and understood. His thought on the topic is crucial for future research on literature as testimony, refering to abnormal conditions of experience whose nature exceeds usual (...) narrative norms. This work is on two components of European culture : French West Indian and Black British literature (memory of slavery) and Spanish literature (civil war and refugees camps). Ce volume prolonge les réflexions du séminaire tenu à Montréal, articulé autour de la question " Dire l'événement, est-ce possible ? ". Les contributions de Gad Soussana ("De l'événement depuis la nuit" suivi de "Arriver") et d'Alexis Nouss ("Parole sans voix") tentent d'en prendre la mesure à partir des problématiques de l'origine et du posthume. Mais l'essentiel, en elles, aura été de susciter la réponse de Jacques Derrida : " Une certaine possibilité impossible de dire l'événement ". Plus qu'une simple rencontre, ce séminaire explicite la présence d'une pensée de l'événement au cœur de l'œuvre littéraire et de l'œuvre philosophique. (shrink)

Carl Craver investigates what we are doing when we sue neuroscience to explain what's going on in the brain.

This article takes a clear-cut case in which a historian ascribes to a writer a concept which neither the writer nor his contemporaries had the linguistic means to express. On the face of it the case may seem a violation of a basic methodological maxim in historiography: "avoid anachronistic ascriptions!" The aim of the article is to show that Koyré's ascription, and others of its kind, are legitimate; and that the methodological maxim should not be given the strict reading which (...) some writers recommend. More specifically, the conceptual repertoire of historical figures need not be reconstructed solely in terms of the social and linguistic conventions of their time and place. (shrink)

Carl F. Craver investigates what we are doing when we use neuroscience to explain what's going on in the brain. When does an explanation succeed and when does it fail? Craver offers explicit standards for successful explanation of the workings of the brain, on the basis of a systematic view about what neuroscientific explanations are.

The development of modern Chinese thought involves an ongoing interaction between internal processes and impacts of foreign ideas. Several intellectual controversies are interwoven into its history and among these one of the more philosophical ones began some 90 years ago, in 1923. In this controversy, supporters of science or scientism and supporters of metaphysics or Confucian tradition debated issues of what both sides referred to as "the view of life." The study of the view of life controversy by Gad C. (...) Isay discusses the positions of the view of life supporters who upheld metaphysics against scientism. It focuses on both the philosophical merit of their views and the relevance of these views to the question of culture in modern China. Considering the sources of the view of life problem in traditional Chinese thought and the discussions that followed after the controversy, it is argued that the view of life question was a central theme in Chinese thought from its beginning. In this respect, modern discussions of this problem indicate continuity with the past. However, these discussions demonstrate too, the dynamics of changing conceptions regarding the context of human relationships that are related directly to the meeting with the West. Isay's study traces the development of these discussions from their beginning up to our days giving a comprehensive survey of the philosophy of the view of life in modern Chinese thought. (shrink)

Numerous sex differences in obsessive-compulsive disorder (OCD) instantiations are likely universal, as the associated evolutionary threats and concerns onto which they map were differentially important to the two sexes. Hence, although some ritualized behaviors or thoughts are indeed culture-specific, others are both culturally and temporally invariant as they are rooted in universal Darwinian etiologies (e.g., the sex differences in OCD symptomatology posited here). (Published Online February 8 2007).

While Qian Mu intentionally avoided systematic philosophical arguments, his references to memory, language, and emotions, as expressed in a book he wrote in 1948, were suggestive of new interpretations of traditional Chinese, and especially Confucian, ideas such as human autonomy, mind, human nature, morality, immortality, and spirituality. The foremost contribution of Qian’s humanist synthesis rests in its articulation of the idea of the person. Across the context of memory, language, and emotions, the tiyong dynamics of mind and human nature recreate, (...) in modern terms, the traditional Chinese concept of the person who is individually unique and simultaneously interrelated. Avoiding the extreme polarities of individualism and collectivism, he stresses rather their coexistence. His synthesis explains to the Chinese people something about who they are, the meaning in life in the framework of their culture, and how their (revitalized) way of life is at its best in the most important area, that of human relations. (shrink)

"Here, for the first time, we have the work of a key pioneer presented in all its depth and range. The pragmatic and prophetic voice of Joseph Ben-David speaks with a power and a clarity that will win the attention of a new generation of scholars."--Arnold Thackray, University of Pennsylvania "A superb collection of brilliant papers by a pioneering mind of international fame, who did much to shape the sociology of science. In organizing this major work, its knowing editor, Gad (...) Freudenthal, has identified a remarkable sociological edifice that exhibits the theoretical coherence of Joseph Ben-David's many-sided and evolving contributions to the field."--Robert K. Merton, Columbia University. (shrink)

An hommage to Gad Freudenthal, this volume offers studies on the history of science and on the role of science in medieval and early-modern Jewish cultures, investigating various aspects of processes of knowledge transfer and scientific cross-cultural contacts,.

One of the most significant political philosophers of the twentieth century, Carl Schmitt is a deeply controversial figure who has been labeled both Nazi sympathizer and modern-day Thomas Hobbes. First published in 1938, The Leviathan in the State Theory of Thomas Hobbes used the Enlightenment philosopher’s enduring symbol of the protective Leviathan to address the nature of modern statehood. A work that predicted the demise of the Third Reich and that still holds relevance in today’s security-obsessed society, this volume (...) will be essential reading for students and scholars of political science. “Carl Schmitt is surely the most controversial German political and legal philosopher of this century. . . . We deal with Schmitt, against all odds, because history stubbornly persists in proving many of his tenets right.”— Perspectives on Political Science “[A] significant contribution. . . . The relation between Hobbes and Schmitt is one of the most important questions surrounding Schmitt: it includes a distinct, though occasionally vacillating, personal identification as well as an association of ideas.”— Telos. (shrink)

In this paper I argue against one variety of contextualism about aesthetic predicates such as “beautiful.” Contextualist analyses of these and other predicates have been subject to several challenges surrounding disagreement. Focusing on one kind of contextualism— individualized indexical contextualism —I unpack these various challenges and consider the responses available to the contextualist. The three responses I consider are as follows: giving an alternative analysis of the concept of disagreement ; claiming that speakers suffer from semantic blindness; and claiming that (...) attributions of beauty carry presuppositions of commonality. I will argue that none of the available strategies gives a response which both satisfactorily explains all of the disagreement -data and is plausible independent of significant evidence in favor of contextualism. I conclude that individualized indexical contextualism about the aesthetic is untenable, although this does not rule out alternative contextualist approaches to the aesthetic. (shrink)

Traces the development of the integral and the differential calculus and related theories since ancient times.

What can be inferred from the fact that something is, or is not, conceivable? In this paper I argue, contrary to some deflationary remarks in recent literature, that arguments which use such facts as their starting point may have significant philosophical import. I use Strawson's results from the first chapter of "Individuals" in order to show that Galileo's arguments in favor of the distinction between primary and secondary qualities, which are based on premises concerning conceivability, should not be dismissed: they (...) are the first step towards recognizing an important conceptual truth. (shrink)

James S. Coleman was the major proponent of rational choice theory. This article challenges the traditional reading of his work by showing that under the explicit theory of rational choice lay a latent non-rational theory of action. The article shows that instead of rationality, Coleman's psychological starting point was existential insecurity; that instead of the alleged mechanism of the maximization of utility, actors choose to conform to peer values and norms in order to alleviate insecurity; and that the optimal setting (...) for action is provided by intimate and dense communities, rather than unregulated free markets. These three non-rational presuppositions are analyzed and it is suggested that they are crucial for understanding Coleman's assessment of modernity, social change and his call for the rational reconstruction of society. (shrink)

This collection of articles and associated discussion papers focuses on a problem that has attracted increasing attention from linguists and psychologists throughout the world during the past several years. Reduced to essentials, the problem is that of discovering the character of the mental capacities that make it possible for human beings to attain knowledge of their language on the basis of fragmentary and haphazard early linguistic experience. A fundamental assumption running through all of these contributions is that people possess strong (...) innate predispositions that are critical for success in this task. (shrink)

Under what conditions are people responsible for their choices and the outcomes of those choices? How could such conditions be fostered by liberal societies? Should what people are due as a matter of justice depend on what they are responsible for? For example, how far should healthcare provision depend on patients' past choices? What values would be realized and which hampered by making justice sensitive to responsibility? Would it give people what they deserve? Would it advance or hinder equality? The (...) explosion of philosophical interest in such questions has been fuelled by increased focus on individual responsibility in political debates. Political philosophers, especially egalitarians, have responded to such developments by attempting to map out the proper place for responsibility in theories of justice. This book both reflects on these recent developments in normative political theory and moves the debate forwards. (shrink)

According to one large family of views, scientific explanations explain a phenomenon (such as an event or a regularity) by subsuming it under a general representation, model, prototype, or schema (see Bechtel, W., & Abrahamsen, A. (2005). Explanation: A mechanist alternative. Studies in History and Philosophy of Biological and Biomedical Sciences, 36(2), 421–441; Churchland, P. M. (1989). A neurocomputational perspective: The nature of mind and the structure of science. Cambridge: MIT Press; Darden (2006); Hempel, C. G. (1965). Aspects of scientific (...) explanation. In C. G. Hempel (Ed.), Aspects of scientific explanation (pp. 331–496). New York: Free Press; Kitcher (1989); Machamer, P., Darden, L., & Craver, C. F. (2000). Thinking about mechanisms. Philosophy of Science, 67(1), 1–25). My concern is with the minimal suggestion that an adequate philosophical theory of scientific explanation can limit its attention to the format or structure with which theories are represented. The representational subsumption view is a plausible hypothesis about the psychology of understanding. It is also a plausible claim about how scientists present their knowledge to the world. However, one cannot address the central questions for a philosophical theory of scientific explanation without turning one’s attention from the structure of representations to the basic commitments about the worldly structures that plausibly count as explanatory. A philosophical theory of scientific explanation should achieve two goals. The first is explanatory demarcation. It should show how explanation relates with other scientific achievements, such as control, description, measurement, prediction, and taxonomy. The second is explanatory normativity. It should say when putative explanations succeed and fail. One cannot achieve these goals without undertaking commitments about the kinds of ontic structures that plausibly count as explanatory. Representations convey explanatory information about a phenomenon when and only when they describe the ontic explanations for those phenomena. (shrink)

Joseph Ben-David (1920-1986) fut un des sociologues des sciences les plus innovateurs et les plus en vue des années soixante et soixante-dix. Travaillant dans le cadre des théories sociologiques de Max Weber, Talcott Parsons et Robert Kmerton, il élabora dans ses ouvrages et nombreux articles une théorie sociologique originale du développement scientifique. Par sa démarche diachronique, il se démarque des sociologues des sciences de l'école fonctionnaliste ; par sa perspective sociologique, il définit des nouvelles problématiques qui viennent s'ajouter à celles (...) des historiens des sciences travaillant dans une optique " internaliste ". Dans le présent ouvrage ont été réunis et traduits les articles les plus importants de Ben-David, qui, ensemble, dessinent les contours d'une sociologie historique des sciences. Par son pouvoir explicatif, cette théorie est à même d'enrichir la pratique de l'historien des sciences, tandis que, par sa réaffirmation des vertus éthiques des rôles sociaux du savant et de l'Université, elle est d'une grande actualité pour les débats sur l'enseignement supérieur en France. (shrink)

In May 1933 the historian of chemistry Hélène Metzger addressed a letter to the renowned historian and philosopher of science Émile Meyerson, a cri de coeur against Meyerson’s patronizing attitude toward her. This recently discovered letter is published and translated here because it is an exceptional human document reflecting the gender power structure of our discipline in interwar France. At the age of forty‐three, and with five books to her credit, Metzger was still a junior scholar in the exclusively male (...) community of French historians and philosophers of science. We sketch the institutional setting of higher learning in France at the time, noting the limited openings it offered to would‐be femmes savantes, and situate Metzger in this context. We also describe the philosophical differences between Metzger and Meyerson. Though Metzger never managed to obtain a post of her own, in her letter to Meyerson she forcefully lays claim, at least, to a mind of her own. (shrink)

The Institutional Animal Care and Use Committee is entrusted with assessing the ethics of proposed projects prior to approval of animal research. The role of the IACUC is detailed in legislation and binding rules, which are in turn inspired by the Three Rs: the principles of Replacement, Reduction, and Refinement. However, these principles are poorly defined. Although this provides the IACUC leeway in assessing a proposed project, it also affords little guidance. Our goal is to provide procedural and philosophical clarity (...) to the IACUC without mandating a particular outcome. To do this, we analyze the underlying logic of the Three Rs and conclude that the Three Rs accord animals moral standing, though not necessarily “rights” in the philosophical sense. We suggest that the Rs are hierarchical, such that Replacement, which can totally eliminate harm, should be considered prior to Reduction, which decreases the number of animals harmed, with Refinement being considered last. We also identify the need for a hitherto implicit fourth R: Reject, which allows the IACUC to refuse permission for a project which does not promise sufficient benefit to offset the pain and distress likely to be caused by the proposed research. (shrink)

It is the purpose of this special issue to acknowledge the shifting definitions and uses of the conceptual and empirical in the field of Science and Technology Studies, and to explore the constructive potential of this condition. In this introductory essay we point to four formulations in STS for the relation between the conceptual and the empirical which do not figure them as binaries or opposites: the empirical as a path to the conceptual, the conceptual as practical and empirical, the (...) empirical as an instantiation of the conceptual, and a conceptual minimalism. We then point to some inspirations in contemporary thought for engaging creatively with the conceptual and empirical, and conclude by summarizing the contributions to this issue. (shrink)

Here a distinguished American historian challenges the belief that the eighteenth century was essentially modern in its temper. In crystalline prose Carl Becker demonstrates that the period commonly described as the Age of Reason was, in fact, very far from that; that Voltaire, Hume, Diderot, and Locke were living in a medieval world, and that these philosophers “demolished the Heavenly City of St. Augustine only to rebuild it with more up-to-date materials.” In a new foreword, Johnson Kent Wright looks (...) at the book’s continuing relevance within the context of current discussion about the Enlightenment. “Will remain a classic—a beautifully finished literary product.”—Charles A. Beard, _American Historical Review_ “_The Heavenly City of the Eighteenth-Century Philosophers _remains_ _one of the most distinctive American contributions to the historical literature on the Enlightenment.... [It] is likely to beguile and provoke readers for a long time to come.”—Johnson Kent Wright, from the foreword. (shrink)

This paper develops a theory of how democratic governance is possible. It analyses democracy as a laminated system consisting of three interdependent levels – the political/institutional, the socia...

We argue that intelligible appeals to interlevel causes (top-down and bottom-up) can be understood, without remainder, as appeals to mechanistically mediated effects. Mechanistically mediated effects are hybrids of causal and constitutive relations, where the causal relations are exclusively intralevel. The idea of causation would have to stretch to the breaking point to accommodate interlevel causes. The notion of a mechanistically mediated effect is preferable because it can do all of the required work without appealing to mysterious interlevel causes. When interlevel (...) causes can be translated into mechanistically mediated effects, the posited relationship is intelligible and should raise no special philosophical objections. When they cannot, they are suspect. (shrink)

Not all models are explanatory. Some models are data summaries. Some models sketch explanations but leave crucial details unspecified or hidden behind filler terms. Some models are used to conjecture a how-possibly explanation without regard to whether it is a how-actually explanation. I use the Hodgkin and Huxley model of the action potential to illustrate these ways that models can be useful without explaining. I then use the subsequent development of the explanation of the action potential to show what is (...) required of an adequate mechanistic model. Mechanistic models are explanatory. (shrink)

Some philosophers writing on the possibility of faultless disagreement have argued that the only way to account for the intuition that there could be disagreements which are faultless in every sense is to accept a relativistic semantics. In this article we demonstrate that this view is mistaken by constructing an absolutist semantics for a particular domain – aesthetic discourse – which allows for the possibility of genuinely faultless disagreements. We argue that this position is an improvement over previous absolutist responses (...) to the relativist's challenge and that it presents an independently plausible account of the semantics of aesthetic discourse. (shrink)