The human experience is shaped by information from different perceptual channels, but it is still debated whether and how differential experience influences language use. To address this, we compared congenitally blind, blindfolded, and sighted people's descriptions of the same motion events experienced auditorily by all participants (i.e., via sound alone) and conveyed in speech and gesture. Comparison of blind and sighted participants to blindfolded participants helped us disentangle the effects of a lifetime experience of being blind versus the task-specific effects (...) of experiencing a motion event by sound alone. Compared to sighted people, blind people's speech focused more on path and less on manner of motion, and encoded paths in a more segmented fashion using more landmarks and path verbs. Gestures followed the speech, such that blind people pointed to landmarks more and depicted manner less than sighted people. This suggests that visual experience affects how people express spatial events in the multimodal language and that blindness may enhance sensitivity to paths of motion due to changes in event construal. These findings have implications for the claims that language processes are deeply rooted in our sensory experiences. (shrink)

This phenomenological-psychological study aims at discovering the essential constituents involved in congenitally blind people's spatial experiences. Nine congenitally blind persons took part in this study. The data were made up of half structured (thorough) interviews. The analysis of the data yielded the following three comprehension forms of spatiality; (i) Comprehension in terms of image-experience; (ii) Comprehension in terms of notions; (iii) Comprehension in terms of knowledge.Comprehension in terms of image experience is the form which is most concretely and clearly experienced. (...) It is important to notice, that this kind of image experience is not synonymous with a visually based image experience — a fact which is discussed in the article. The following three features, which are to be understood as a description of what characterizes congenitally blind people's image experience, are presented; (i) Experience of the whole; (ii) Synthesizing/Harmonizing; (iii) Spontanous presentation of the whole. Furthermore, comprehension in terms of image experience is made up of the following four constituents, which aim at specifying the conditions for the possibility of having an image experience; (i) The image experience is based on tactile experiences; (ii) The inner horizon of the object has to be limited in order for the tactile sense to constitute an image experience; (iii) The person must have reached a certain degree of familiarity with the object; (iv) The importance of the emotional investment in the object. (shrink)

Sighted speakers of different languages vary systematically in how they package and order components of a motion event in speech. These differences influence how semantic elements are organized in gesture, but only when those gestures are produced with speech, not without speech. We ask whether the cross-linguistic similarity in silent gesture is driven by the visuospatial structure of the event. We compared 40 congenitally blind adult native speakers of English or Turkish to 80 sighted adult speakers as they described three-dimensional (...) motion scenes. We found an effect of language on co-speech gesture, not on silent gesture—blind speakers of both languages organized their silent gestures as sighted speakers do. Humans may have a natural semantic organization that they impose on events when conveying them in gesture without language—an organization that relies on neither visuospatial cues nor language structure. (shrink)

Haptic object recognition is usually an efficient process although slower and less accurate than its visual counterpart. The early loss of vision imposes a greater reliance on haptic perception for recognition compared to the sighted. Therefore, we may expect that congenitally blind persons could recognize objects through touch more quickly and accurately than late blind or sighted people. However, the literature provided mixed results. Furthermore, most of the studies on haptic object recognition focused on performance, devoting little attention to the (...) exploration procedures that conducted to that performance. In this study, we used iCube, an instrumented cube recording its orientation in space as well as the location of the points of contact on its faces. Three groups of congenitally blind, late blind and age and gender-matched blindfolded sighted participants were asked to explore the cube faces where little pins were positioned in varying number. Participants were required to explore the cube twice, reporting whether the cube was the same or it differed in pins disposition. Results showed that recognition accuracy was not modulated by the level of visual ability. However, congenitally blind touched more cells simultaneously while exploring the faces and changed more the pattern of touched cells from one recording sample to the next than late blind and sighted. Furthermore, the number of simultaneously touched cells negatively correlated with exploration duration. These findings indicate that early blindness shapes haptic exploration of objects that can be held in hands. (shrink)

Spatial memory relies on encoding, storing, and retrieval of knowledge about objects’ positions in their surrounding environment. Blind people have to rely on sensory modalities other than vision to memorize items that are spatially displaced, however, to date, very little is known about the influence of early visual deprivation on a person’s ability to remember and process sound locations. To fill this gap, we tested sighted and congenitally blind adults and adolescents in an audio-spatial memory task inspired by the classical (...) card game “Memory.” In this research, subjects had to find pairs among sounds displaced on an audio-tactile device composed of loudspeakers covered by tactile sensors. To accomplish this task, participants had to remember the spatialized sounds’ position and develop a proper mental spatial representation of their locations. The test was divided into two experimental conditions of increasing difficulty dependent on the number of sounds to be remembered. Results showed that sighted participants outperformed blind participants in both conditions. Findings were discussed considering the crucial role of visual experience in properly manipulating auditory spatial representations, particularly in relation to the ability to explore complex acoustic configurations. (shrink)

My concerns are about the phrase “the nature of imagery,” and the interpretation of findings with blind people. This discussion considers reports of imagery by congenitally totally blind people, and what should not be inferred from comparing efficiency levels of blind and sighted people in spatial tasks.

The repeatedly noted absence of case-reports of individuals with schizophrenia and congenital/early developed blindness has led several authors to argue that the latter can confer protective effects against the former. In this work, we present a number of relevant case-reports from different syndromes that show comorbidity of congenital and early blindness with schizophrenia. On the basis of these reports, we argue that a distinction between different types of blindness in terms of the origin of the (...) visual deficit, cortical or peripheral, is crucial for understanding the observed patterns of comorbidity. We discuss the genetic underpinnings and the brain structures involved in schizophrenia and blindness, with insights from language processing, laying emphasis on the three structures that particularly stand out: the occipital cortex, the lateral geniculate nucleus and the pulvinar. Last, we build on previous literature on the nature of the protective effects in order to offer novel insights into the nature of the protection mechanism from the perspective of the brain structures involved in each type of blindness. (shrink)

The notion that manual gestures played an important role in the evolution of human language was strengthened by the discovery of mirror neurons in monkey area F5, the proposed homologue of human Broca's area. This idea is central to the thesis developed by Arbib, and lending further support to a link between motor resonance mechanisms and language/communication development is the case of autism and congenital blindness. We provide an account of how these conditions may relate to the aforementioned (...) theory. (shrink)

Congenital nystagmus in infants and young children can lead to early blindness. Previous neuroimaging studies have demonstrated that EB is accompanied by alterations in brain structure and function. However, the effects of visual impairment and critical developmental periods on brain functional connectivity at rest have been unclear. Here, we used the voxel-wise degree centrality method to explore the underlying functional network brain activity in adolescents with EB. Twenty-one patients with EBs and 21 sighted controls underwent magnetic resonance imaging. (...) Differences between the two groups were assessed using the DC method. Moreover, the support vector machine method was used to differentiate patients with EB patients from the SCs according to DC values. Compared with the SCs, the patients with EB had increased DC values in the bilateral cerebellum_6, cerebellum vermis_4_5, bilateral supplementary motor areas, and left fusiform gyrus; the patients with EB had decreased DC values in the bilateral rectal gyrus and left medial orbital frontal gyrus. The SVM classification of the DC values achieved an overall accuracy of 70.45% and an area under the curve of 0.86 in distinguishing between the patients with EB and the SCs. Our study may reveal the neuromechanism of neuroplasticity in EB; the findings provide an imaging basis for future development of restorative visual therapies and sensory substitution devices, and future assessments of visual rehabilitation efficacy. (shrink)

This book breaks new ground in our understanding of how we perceive and represent the space around us - one of the central topics in cognitive psychology. It presents a new view of development and spatial cognition by reversing the usual focus on vision and examining the evidence on representation in the total absence of vision without specific brain damage. Findings from the author's work with congenitally totally blind and with sighted children, together with studies from a wide variety of (...) other areas, are set in the context of intersensory and spatial development. Touch and movement are considered as converging sources of reference information with and without vision. The findings have important implications for future work in many fields, particularly developmental pscychology; cognition, cognitive neuroscience and visual handicap, and make this new work essential reading for students and researchers in these fields. (shrink)

Congenitally blind people can make and understand ‘tactile pictures’ – representations form of raised ridges on flat surfaces. If made visible, these representations can serve as pictures for the sighted. Does it follow that we should take at face value the idea that they are pictures made for touch? I explore this question, and the related issue of the aesthetics of ‘tactile pictures’ by considering the role in both depiction and pictorial aesthetics of experience, and by asking how far the (...) experience of those engaging with representations through touch can approximate to that of those engaging with them through sight. (shrink)

Ethical thought experiments such as the trolley dilemma have been investigated extensively in the past, showing that humans act in utilitarian ways, trying to cause as little overall damage as possible. These trolley dilemmas have gained renewed attention over the past few years, especially due to the necessity of implementing moral decisions in autonomous driving vehicles. We conducted a set of experiments in which participants experienced modified trolley dilemmas as drivers in virtual reality environments. Participants had to make decisions between (...) driving in one of two lanes where different obstacles came into view. Eventually, the participants had to decide which of the objects they would crash into. Obstacles included a variety of human-like avatars of different ages and group sizes. Furthermore, the influence of sidewalks as potential safe harbors and a condition implicating self-sacrifice were tested. Results showed that participants, in general, decided in a utilitarian manner, sparing the highest number of avatars possible with a limited influence by the other variables. Derived from these findings, which are in line with the utilitarian approach in moral decision making, it will be argued for an obligatory ethics setting implemented in ADVs. (shrink)

After more than three centuries, Molyneux's question continues to challenge our understanding of cognition and perceptual systems. Locke, the original recipient of the question, approached it as a theoretical exercise relevant to long-standing philosophical issues, such as nativism, the possibility of common sensibles, and the empiricism-rationalism debate. However, philosophers were quick to adopt the experimentalist's stance as soon as they became aware of recoveries from congenital blindness through ophtalmic surgery. Such recoveries were widely reported to support empiricist positions, (...) suggesting that the question had found its empirical answer. Contrary to this common view, we argue that studies of patients recovering from early blindness through surgery cannot provide an answer. In fact, because of the very nature of such ophtalmological interventions it is impossible to test the question in the empirical conditions outlined by Molyneux. Thus we propose that Molyneux's question be treated as an early thought experiment of a specific kind. Although thought experiments of this kind cannot be turned into actual experimental conditions, they provide a conceptual restructuring of theories. Such restructuring in turn leads to new predictions that can then be tested by normal experiments. In accord with this interpretation, we show that Molyneux's question can be analyzed into a hierarchy of specific questions about vision in its phenomenal and sensory-motor components. Some of these questions do lead to actual experimental conditions that could be studied empirically. (shrink)

Sensory substitution devices (SSDs) are most familiar from their use with subjects who are deficient in a target modality (e.g. congenitally blind subjects), but there is no doubt that the use and potential value of SSDs extend to persons without such deficits. Recent work by Amedi and his team (in particular Levy-Tzedek et al. 2012) has begun to explore this. Their idea is that SSDs may facilitate behavioural transference (BT) across sense modalities. In this case, a motor skill learned through (...) visual perception might be subsequently employed in response to auditory perception, using an SSD as a mediator. They infer from the existence of such BT that the learned skill is amodally represented. After a brief overview I identify ways to more fully test for BT within this experimental paradigm and argue that their conclusion about amodal representation is premature. Additionally, I argue that their preferred SSD (Eyemusic) is of limited value for the project. While my remarks are critical, my intention is to be constructive, particularly in light of the fact that Levy-Tzedek et al. (2012), is, I believe, the first output from Amedi's lab concerning this line of research. (shrink)

Advocates of the pictorial theory of meaning claimed that the meaning of a word is a mental picture and that lexical semantic competence --i.e. knowledge of word meaning -- is closely connected to visual imagery. As a philosophical theory of meaning, the pictorial theory was discredited in the twentieth century. Nevertheless, there is evidence that visual imagery -- the generation of visual mental images -- does play a role in semantic processing and is not just a possible side effect of (...) it. The aim of this article is to critically assess the neuroscientific status of the pictorial theory of meaning as a hypothesis about the neurocognitive underpinnings of lexical semantic competence. I will assess relevant neuroimaging, behavioural, and patient data, as well as data from congenital blindness studies. (shrink)

After more than three centuries, Molyneux's question continues to challenge our understanding of cognition and perceptual systems. Locke, the original recipient of the question, approached it as a theoretical exercise relevant to long-standing philosophical issues, such as nativism, the possibility of common sensibles, and the empiricism-rationalism debate. However, philosophers were quick to adopt the experimentalist's stance as soon as they became aware of recoveries from congenital blindness through ophtalmic surgery. Such recoveries were widely reported to support empiricist positions, (...) suggesting that the question had found its empirical answer. Contrary to this common view, we argue that studies of patients recovering from early blindness through surgery cannot provide an answer. In fact, because of the very nature of such ophtalmological interventions it is impossible to test the question in the empirical conditions outlined by Molyneux. Thus we propose that Molyneux's question be treated as an early thought experiment of a specific kind. Although thought experiments of this kind cannot be turned into actual experimental conditions, they provide a conceptual restructuring of theories. Such restructuring in turn leads to new predictions that can then be tested by “normal” experiments. In accord with this interpretation, we show that Molyneux's question can be analyzed into a hierarchy of specific questions about vision in its phenomenal and sensory-motor components. Some of these questions do lead to actual experimental conditions that could be studied empirically. (shrink)

Este artigo propõe-se a refletir sobre a construção do Eu de crianças com cegueira congênita a partir da teoria winnicottiana do amadurecimento. Para Winnicott, a natureza humana é uma questão de psique-soma em constante interação; o ser humano é essencialmente psicossomático, sendo o corpo o primeiro a chegar e a elaboração imaginativa das funções corpóreas o elemento constitutivo e enriquecedor da vida psíquica. Essa concepção da natureza humana parece ser a mais esclarecedora para a compreensão do desenvolvimento e da construção (...) do eu das crianças com cegueira congênita; crianças que chegam ao mundo com uma constituição orgânica significativamente diferente, que as conduzem por caminhos peculiares em seu processo de percepção e amadurecimento. Muitas dificuldades são apontadas na descrição do desenvolvimento dessas crianças: passividade de ego, ausência de interesse por objetos, atrasos na aquisição de capacidades, desinteresse por brincadeiras e verbalismo. Comportamentos considerados semelhantes aos de crianças autistas. Acreditamos que, a partir da teoria winnicottiana do desenvolvimento, muitas dessas vicissitudes podem ser compreendidas e alguns procedimentos terapêuticos indicados.This article proposes a reflection upon the ego development of children with congenital blindness through maturation theory. For Winnicott the human nature is a matter of psyche-some in constant interaction, the human being is essentially psychosomatic, in which the body is the first to arrive and the imaginative elaboration of the body functions are the elements that constitute and enrich the psychic life. This conception of the human nature seems to be the most clarifying for the comprehension of the development and the self constitution of the children with congenital blindness; children who arrive into the world with a significantly different organic constitution, which conducts them through a peculiar path in their process of perception and maturity. Many difficulties are pointed out on the description of the development of these children: passivity of the ego, absence of interest for objects, delay on the acquisition of abilities, disinterest for children's play, verbalism. Behaviors similar to those of autistic children. We believe that through Winnicott's developmental theory a lot of these vicissitudes can be comprehended and some therapeutic procedures can be indicated. (shrink)

The aim of this chapter is to shed new light on the question of what newly sighted subjects are capable of seeing on the basis of previous experience with mind- independent, external objects and their properties through touch alone. This question is also known as "Molyneux’s question." Much of the empirically driven debate surrounding this question has been centered on the nature of the representational content of the subjects' visual experiences. It has generally been assumed that the meaning of "seeing" (...) deployed in these disputes is more or less clear and unproblematic, and therefore requires no analysis or clarification. In this chapter, we wish to challenge this assumption. We argue that getting clear on the meaning of "seeing" is the only feasible way to determine whether the empirical attempts to answer Molyneux’s question accurately capture what newly sighted subjects are in fact capable of seeing. Specifically, we show that the dominant interpretations of the empirical results from a recent study (Held et al., 2011) fail to take into account that seeing can be not only purely visual but also epistemic in that it requires background knowledge (such as what an object with a particular viewpoint-independent shape looks like from a particular perspective). (shrink)

Vigil suggests that expressed emotions are inherently learned and triggered in social contexts. A strict reading of this account is not consistent with the findings that individuals, even those who are congenitally blind, do express emotions in the absence of an audience. Rather, grounded cognition suggests that facial expressions might also be an embodied support used to represent emotional information.

This book argues that a descriptive, systematic, non-intuitive semantics cannot be provided for a natural language: that while a non-intuitive, formal explication can be provided for the competent speaker’s intuitions about grammaticality, this has not been, and likely cannot be, provided for such a speaker’s intuitions of synonymy, analyticity, and significance. Tartaglia concludes that Quine has actually established, not that we do not have an intuitive, informal notion of the analytic-synthetic distinction, but rather that we have failed, and likely will (...) fail, at providing "a practical, nonintuitive procedure for deciding, irrespective of extra linguistic content, whether a given statement is analytic or synthetic." "[Since] the language of knowledge consists of a system or systems in which no single statement can be said to be true or false in isolation from other statements in its system, then the lexicographer’s problem is insoluble". Tartaglia criticizes the 1964 Katz-Fodor paper, "The Structure of a Semantic Theory" by the undiminishing flea method: the bachelor finally dies is ambiguous both by theory and intuition; but the old bachelor finally dies requires the addition of a semantic marker,, to bring theory in line with intuition ; and the congenitally blind bachelor finally dies will make another semantic marker necessary and so on. But the trick can be worked with grammaticality too. Tartaglia suggests that grammaticality is well on its way to a reasonably adequate explication, while synonymy, etc., is not. (shrink)

It is widely assumed that the art media can be individuated with reference to the sense modalities. Different art media are perceived by means of different sense modalities, and this tells us what properties of each medium are aesthetically relevant. The case of pictures appears to fit this principle well, for pictures are deemed purely and paradigmatically visual representations. However, recent psychological studies show that congenitally and early blind people have the ability to interpret and make raised‐line drawings through touch. (...) This shows that pictures are not essentially visual representations. The view that pictures are essentially visual follows from influential views of the nature of depiction and of the nature of vision that are mistaken. By rooting out the mistake, we learn something about pictures, something about vision, and something about the doctrine that art media are individuated by the sense modalities. (shrink)

Diseases causing inherited retinal degeneration in humans, such as retinitis pigmentosa and macular dystrophy, are genetically heterogeneous and clinically diverse. More than 40 genes causing retinal degeneration have been mapped to specific chromosomal sites; of these, at least 10 have been cloned and characterized. Mutations in two proteins, rhodopsin and peripherin/RDS, account for approximately 35% of all cases of autosomal dominant retinitis pigmentosa and a lesser fraction of other retinal conditions. This target article reviews the genes and mutations causing retinal (...) degeneration and proposes mechanisms whereby specific mutations lead to particular clinical consequences, that is, the relationship between genotype and phenotype. Retinitis pigmentosa and macular dystrophy are genetically heterogeneous diseases that cause retinal degeneration in humans and often result in severe visual impairment or blindness. Although many of the genes causing these diseases have not been identified, three photoreceptor-specific proteins have been implicated: rhodopsin, peripherin/RDS, and the P-subunit of rod phosphodiesterase. Mutations in the genes for these three proteins can cause either dominant retinitis pigmentosa, recessive retinitis pigmentosa, dominant congenital stationary night blindness, or dominant macular degeneration. Why this multiplicity of clinical phenotypes? Our target article summarizes the genetic and biochemical background to this question and proposes a number of possible explanations. Discussion focuses mainly on 73 distinct disease-causing mutations of rhodopsin. We feel that rhodopsin and other photoreceptor proteins can serve as model systems for unraveling the connection between genotype and phenotype, not only for inherited retinal diseases but for other degenerative disorders as well. (shrink)

This paper characterizes the crisis of expertise, especially as it manifested during the covid-19 pandemic, as a crisis of trust in regulatory science. The temporal structure of the facts produced by regulatory science differs from Kuhnian “normal science,” while they also contain profound distributional implications. As a result, they suffer from a set of congenital problems that provoke mistrust in a way that normal science facts do not. While “expertise” is often offered as an answer to these problems, the (...) paper shows that it is a symptom of the malaise, reflecting a situation where it is no longer clear how to decide between competing claims to authority as experts. The current mistrust in experts and regulatory science during the pandemic, therefore, is part of a longer and systemic crisis of expertise provoked and sustained by multiple factors. The paper then offers an unsystematic set of rules of method to observe when addressing the thorny issues involving trust and mistrust: 1) trust is not a subjective attitude that can be measured by a survey; 2) mistrust is not the opposite of trust; 3) trust is a social skill involving a set of ethnomethods for distinguishing between responsible and “blind” trust; 4) attention to temporal framing is key to these methods; 5) disruption of this temporal framing – as routinely happens with regulatory facts, and especially during the pandemic – destroys trust. (shrink)

This book provides a detailed account of intellectual, other neuropsychological and behavioral manifestations of general pediatric diseases. The conditions discussed include the whole range of pediatric diseases - genetic syndromes, other congenital conditions, metabolic, endocrine, gastrointestinal, infectious, immunologic, toxic, trauma, and neoplastic, as well as sensory disabilities including deafness and blindness. Although the book is not intended to discuss cognitive and behavioral manifestations of conditions usually considered to be primary neurological disease, some of those, including cerebral palsy, muscular (...) dystrophy, myotonic dystrophy and epilepsy, are included.Where possible, a. (shrink)

For almost 30 years the ion channel that initiates the ON visual pathway in vertebrate vision has remained elusive. Recent findings now indicate that the pathway, which begins with unbinding of glutamate from the metabotropic glutamate receptor 6 (mGluR6), ends with the opening of the transient receptor potential (TRP)M1 cation channel. As a component of the mGluR6 signal transduction pathway, mutations in TRPM1 would be expected to cause congenital stationary night blindness (CSNB), and several such mutations have already (...) been identified in CSNB families. Furthermore, expression of TRPM1 in both the retina and skin raises the possibility that a genetic link exists between certain types of visual and skin disorders. (shrink)

Large changes that occur in clear view of an observer can become difficult to notice if made during an eye movement, blink, or other such disturbance. This change blindness is consistent with the proposal that focused visual attention is necessary to see change, with a change becoming difficult to notice whenever conditions prevent attention from being automatically drawn to it. -/- It is shown here how the phenomenon of change blindness can provide new results on the nature of (...) visual attention, including estimates of its capacity and the extent to which it can bind visual properties into coherent descriptions. It is also shown how the resultant characterization of attention can in turn provide new insights into the role that it plays in the perception of scenes and events. (shrink)

Following extensive examination of published and unpublished materials, we provide a history of the use of dexamethasone in pregnant women at risk of carrying a female fetus affected by congenital adrenal hyperplasia (CAH). This intervention has been aimed at preventing development of ambiguous genitalia, the urogenital sinus, tomboyism, and lesbianism. We map out ethical problems in this history, including: misleading promotion to physicians and CAH-affected families; de facto experimentation without the necessary protections of approved research; troubling parallels to the (...) history of prenatal use of diethylstilbestrol (DES); and the use of medicine and public monies to attempt prevention of benign behavioral sex variations. Critical attention is directed at recent investigations by the U.S. Food and Drug Administration (FDA) and Office of Human Research Protections (OHRP); we argue that the weak and unsupported conclusions of these investigations indicate major gaps in the systems meant to protect subjects of high-risk medical research. (shrink)

When confronted with an ethical dilemma, most of us like to think we would stand up for our principles. But we are not as ethical as we think we are. In Blind Spots, leading business ethicists Max Bazerman and Ann Tenbrunsel examine the ways we overestimate our ability to do what is right and how we act unethically without meaning to. From the collapse of Enron and corruption in the tobacco industry, to sales of the defective Ford Pinto, the downfall (...) of Bernard Madoff, and the Challenger space shuttle disaster, the authors investigate the nature of ethical failures in the business world and beyond, and illustrate how we can become more ethical, bridging the gap between who we are and who we want to be. Explaining why traditional approaches to ethics don't work, the book considers how blind spots like ethical fading--the removal of ethics from the decision--making process--have led to tragedies and scandals such as the Challenger space shuttle disaster, steroid use in Major League Baseball, the crash in the financial markets, and the energy crisis. The authors demonstrate how ethical standards shift, how we neglect to notice and act on the unethical behavior of others, and how compliance initiatives can actually promote unethical behavior. They argue that scandals will continue to emerge unless such approaches take into account the psychology of individuals faced with ethical dilemmas. Distinguishing our "should self" from our "want self", the authors point out ethical sinkholes that create questionable actions. Suggesting innovative individual and group tactics for improving human judgment, Blind Spots shows us how to secure a place for ethics in our workplaces, institutions, and daily lives. (shrink)

This article is the first indepth ethical analysis of empirical studies that support the claim that children born without major parts of their cerebral cortex are capable of conscious experiences and have a rudimentary capacity for agency. Congenitally decorticate children have commonly been classified as persistently vegetative, with serious consequences for their well-being and opportunities to flourish. The paper begins with an explication of the rights-based normative framework of the argument, including conceptual analysis of the terms ‘agency’, ‘potentiality for agency’ (...) and ‘gradual approach of agency’. It critically examines Alan Gewirth’s account of the criteria for being a rights bearer and principles for settling rights conflicts between agents and potential agents. It then applies the rights-based normative framework to the ethical challenges associated with care for congenitally decorticate children. It argues that recent empirical studies support the claim that the concepts ‘potential for agency’ and ‘capacity for rudimentary agency’ apply to children who are born without major parts of their cerebral cortex. The article finally discusses important medical ethical implications of these results. It specifically focuses on congenitally decorticate children’s preparatory rights to a stimulating intellectual and social environment. (shrink)

The paper asks under what conditions deductive reasoning transmits justification from its premises to its conclusion. It argues that both standard externalist and standard internalist accounts of this phenomenon fail. The nature of this failure is taken to indicate the way forward: basic forms of deductive reasoning must justify by being instances of 'blind but blameless' reasoning. Finally, the paper explores the suggestion that an inferentialist account of the logical constants can help explain how such reasoning is possible.

Normativists about belief hold that belief formation is essentially rule- or norm-guided. On this view, certain norms are constitutive of or essential to belief in such a way that no mental state not guided by those norms counts as a belief, properly construed. In recent influential work, Kathrin Glüer and Åsa Wikforss develop novel arguments against normativism. According to their regress of motivations argument, not all belief formation can be rule- or norm-guided, on pain of a vicious infinite regress. I (...) argue that the regress of motivations argument is unsuccessful: an appeal to the notion of blind rule-following, drawn from a plausible interpretation of Ludwig Wittgenstein’s remarks on rule-following, stops the regress of motivations in its tracks. (shrink)

In this chapter a new problem about rule-following is outlined, one that is distinct both from Kripke’s and Wright’s versions of the problem. This new problem cannot be correctly responsed to, as Kripke’s can, by invoking Wright’s Intentional Account of rule-following. The upshot might be called, following Kant, an antinomy of pure reason: we both must — and cannot — make sense of someone’s following a rule. The chapter explores various ways out of this antinomy without here endorsing any of (...) them. (shrink)

Chagas disease or American trypanosomiasis is an important health problem in Latin America. Due to the mobility of Latin American population around the world, countries without vector presence started to report disease cases. We developed a deterministic compartmental model in order to gain insights into the disease dynamics in a scenario without vector presence, considering congenital transmission and transmission by blood transfusion. The model was used to evaluate the epidemiological effect of control measures. It was applied to demographic data (...) from Spain and sensitivity analysis was performed on model parameters associated with control strategies. (shrink)

Abstract: To evaluate the explanation of change blindness in terms of misrepresentation and determine its role for Rosenthal’s higher-order thought theory of consciousness, we present an alternative account of change blindness that affords an independent outlook and provides a viable alternative. First we describe Rosenthal’s actualism and the notion of misrepresentation, then introduce change blindness and the explanation of it by misrepresentation. Rosenthal asserts that, in change blindness, the first-order state tracks the post-change stimulus, but the (...) higher-order state misrepresents it. We propose the alternative that both post-change and pre-change content can be tracked by the first-order state, and that in change blindness the higher-order thought represents the pre-change state, resulting in a good-enough representation: true but not veridical. We compare the two explanations with respect to available data and analyse the principal theoretical claims. Discussing the rationale of the alternative account, we conclude that there is good reason to conceive of the mind as satisficing, geared towards reliability instead of truth-tracking, and guided by representations that are good enough as opposed to complete or corresponding to the facts. We end with some methodological remarks concerning the risk of cognitive biases in interdisciplinary research that brings together empirical and philosophical claims. (shrink)

When confronted with an ethical dilemma, most of us like to think we would stand up for our principles. But we are not as ethical as we think we are. In Blind Spots, leading business ethicists Max Bazerman and Ann Tenbrunsel examine the ways we overestimate our ability to do what is right and how we act unethically without meaning to. From the collapse of Enron and corruption in the tobacco industry, to sales of the defective Ford Pinto, the downfall (...) of Bernard Madoff, and the Challenger space shuttle disaster, the authors investigate the nature of ethical failures in the business world and beyond, and illustrate how we can become more ethical, bridging the gap between who we are and who we want to be. Explaining why traditional approaches to ethics don't work, the book considers how blind spots like ethical fading--the removal of ethics from the decision--making process--have led to tragedies and scandals such as the Challenger space shuttle disaster, steroid use in Major League Baseball, the crash in the financial markets, and the energy crisis. The authors demonstrate how ethical standards shift, how we neglect to notice and act on the unethical behavior of others, and how compliance initiatives can actually promote unethical behavior. They argue that scandals will continue to emerge unless such approaches take into account the psychology of individuals faced with ethical dilemmas. Distinguishing our "should self" from our "want self", the authors point out ethical sinkholes that create questionable actions. Suggesting innovative individual and group tactics for improving human judgment, Blind Spots shows us how to secure a place for ethics in our workplaces, institutions, and daily lives. (shrink)

I take the phrase ‘congenital transcendentalism’ from Santayana who defined it as ‘the spontaneous feeling that life is a dream’. ‘The loneliness which is the truth about things’ is a phrase of Virginia Woolf's. The thesis I will advance is that many expressions of doubt or denial of the shareable world are self-misunderstood manifestations of the state indicated by Woolf's expression. But the loneliness of which Woolf speaks must not be construed as the kind of loneliness which can be (...) assuaged by family, friends, lovers or company. Nor is it the loneliness which a convinced solipsist might experience. It is rather the loneliness of ‘that “I” and that “life of mine'” which is ‘untouched whichever way the issue is decided whether the world is or is not’. (shrink)