Awareness of internal bodily sensations and its connection to complex socioemotional abilities like empathy has been postulated, yet the functional neural circuitry they share remains poorly understood. The present fMRI study employs independent component analysis to investigate which empathy facet shares resting-state functional connectivity and/or BOLD variability with IA. Healthy participants viewed an abstract nonsocial movie demonstrated to evoke strong rsFC in brain networks resembling rest, and resultant rsFC and rsBOLD data were correlated with self-reported empathy and IA questionnaires. We (...) demonstrate a bidirectional behavioral and neurobiological relationship between empathy and IA, depending on the type of empathy interrogated: Affective empathy and IA share both rsFC and rsBOLD, while Cognitive empathy and IA only share rsBOLD. Specifically, increased rsFC in the right inferior frontal operculum of a larger attention network was associated with increased vicarious experience but decreased awareness of inner body sensations. Furthermore, increased rsBOLD between brain regions of an interoceptive network was related to increased sensitivity to internal sensations along with decreased Affective empathy. Finally, increased rsBOLD between brain regions subserving a mentalizing network related to not only an improved ability to take someone’s perspective, but also a better sense of mind-body interconnectedness. Overall, these findings suggest that the awareness of one’s own internal body changes is related to the socioemotional ability of feeling and understanding another’s emotional state and critically, that this relationship is reflected in the brain’s resting state neuroarchitecture. Methodologically, this work highlights the importance of utilizing rsBOLD as a complementary window alongside rsFC to better understand neurological phenomena. Our results may be beneficial in aiding diagnosis in clinical populations such as autism spectrum disorder, where participants may be unable to complete tasks or questionnaires due to the severity of their symptoms. (shrink)

In this vivid and incisive guide, philosophy comes to life. Using the central idea of causality as a guiding principle, Brendan Wilson shows how the history of philosophy becomes a very clear and natural sequence of events. The resulting perspective reveals the deep connections between the problems of science, mind and reality, freedom and responsibility, knowledge, language, truth and religion. Newcomers to philosophy will be able to engage with the great questions and ideas of the western tradition. The writing (...) is clear and jargon-free, while the 'short-chapter' format gives the reader time to pause and think at each step along the way. Style and layout put accessibility first and the many illustrations include explanatory diagrams and drawings as well as pictures of philosophers from Aristotle to Wittgenstein. Key Features Encourages critical and independent thinking Written in an engaging, non-technical style Makes clear sense of philosophy's rich and complex history Presents a distinctive argument Provides a wide range of case studies and examples from philosophy, science and law Text Features Chapter overviews Chapter sub-headings for ease of use Carefully-chosen quotations from philosophers ancient and modern End of chapter discussion points An open and attractive page layout Lavish and relevant illustrations, including photographs, diagrams, explanatory boxes and drawings. (shrink)

Extraversion has two central characteristics: (1) interpersonalengagement, which consists of affiliation (enjoying and valuing close interpersonal bonds, being warm and affectionate) and agency (being socially dominant, enjoying leadership roles, being assertive, being exhibitionistic, and having a sense of potency in accomplishing goals) and (2) impulsivity, which emerges from the interaction of extraversion and a second, independent trait (constraint). Agency is a more general motivational disposition that includes dominance, ambition, mastery, efficacy, and achievement. Positive affect (a combination of positive feelings and (...) motivation) is closely associated with extraversion. Extraversion is accordingly based on positiveincentivemotivation. (shrink)

Because little is known about the human trait of affiliation, we provide a novel neurobehavioral model of affiliative bonding. Discussion is organized around processes of reward and memory formation that occur during approach and consummatory phases of affiliation. Appetitive and consummatory reward processes are mediated independently by the activity of the ventral tegmental area (VTA) dopamine (DA)–nucleus accumbens shell (NAS) pathway and the central corticolimbic projections of the u-opiate system of the medial basal arcuate nucleus, respectively, although these two projection (...) systems functionally interact across time. We next explicate the manner in which DA and glutamate interact in both the VTA and NAS to form incentive-encoded contextual memory ensembles that are predictive of reward derived from affiliative objects. Affiliative stimuli, in particular, are incorporated within contextual ensembles predictive of affiliative reward via: (a) the binding of affiliative stimuli in the rostral circuit of the medial extended amygdala and subsequent transmission to the NAS shell; (b) affiliative stimulus-induced opiate potentiation of DA processes in the VTA and NAS; and (c) permissive or facilitatory effects of gonadal steroids, oxytocin (in interaction with DA), and vasopressin on (i) sensory, perceptual, and attentional processing of affiliative stimuli and (ii) formation of social memories. Among these various processes, we propose that the capacity to experience affiliative reward via opiate functioning has a disproportionate weight in determining individual differences in affiliation. We delineate sources of these individual differences, and provide the first human data that support an association between opiate functioning and variation in trait affiliation. Key Words: affiliation corticolimbic-striatal networks; appetitive and consummatory reward; dopamine; oxytocin; personality; social bonds; social memory; u-opiates. (shrink)

Lifelines supports the theme that behavioral development is a fluid, life-long phenomenon. In contrast, many emotional and cognitive traits are subject to strong genetic influence, and are highly stable over many years. The manner in which neuroplasticity and trait stability cooccur needs to be modeled. An outline of such a model is provided to promote discussion of this complex issue.

本书探讨了西方自由主义普遍主义产生的社会历史根源,考察了它的三种主要论证形式及其某些变种,分析了每种论证形式的认识论根源和误区。.

Mechanistic philosophy of science views a large part of scientific activity as engaged in modelling mechanisms. While science textbooks tend to offer qualitative models of mechanisms, there is increasing demand for models from which one can draw quantitative predictions and explanations. Casini et al. (Theoria 26(1):5–33, 2011) put forward the Recursive Bayesian Networks (RBN) formalism as well suited to this end. The RBN formalism is an extension of the standard Bayesian net formalism, an extension that allows for modelling the hierarchical (...) nature of mechanisms. Like the standard Bayesian net formalism, it models causal relationships using directed acyclic graphs. Given this appeal to acyclicity, causal cycles pose a prima facie problem for the RBN approach. This paper argues that the problem is a significant one given the ubiquity of causal cycles in mechanisms, but that the problem can be solved by combining two sorts of solution strategy in a judicious way. (shrink)

Purcell, Brendan The Focolare Movement is officially known as the Work of Mary, and since it is primarily a lay movement, it falls under the authority of the Congregation for the Laity. Its founder, Chiara Lubich, was born in Trent in 1920, the second of four children, into a close-knit family. Her mother was a devout daily Massgoing Catholic, her father, a socialist, uninterested in religion, but a man of principle, whose refusal to join the Fascist party lost him (...) any chance of a regular job after the 1929 Depression. (shrink)

As modern viewers, it is tempting to interpret Frank and Claire’s manipulations of democratic institutions as representing perversions or distortions of democratic ideals. After all, most of us think (or at least hope!) that real-world democracies we actually live in aren’t quite that badly governed. Whatever the moral faults of our leaders are, they don’t (as a rule) murder journalists, crudely provoke international crises for political gain, or cleverly set up their political adversaries with Bond-villain-like cunning. Real politicians, so the (...) story goes, lack the cleverness, the ruthlessness, and the luck of the Underwoods. While this sort of faith in the general validity of democratic ideals and institutions is now widely shared, the Underwoods’ clever “gaming” of the system can also be seen as providing an especially clear illustration of some of the things that might be inherently wrong with democracy. In this essay, I’ll take a look at how the Underwoods’ behavior might look to some of the most famous critics of democratic government, including Plato, Thomas Hobbes, and Karl Marx. According to these thinkers, the most significant flaws that Underwoods exploit to gain political power have little, if anything, to do with the peculiarity of their talents, the weaknesses of the individuals around them, or even the structures of the US political system. Instead, their success is made possible by certain fundamental features of democratic government, features that guarantee both the instability and eventual failure of any democratic government. On this reading, the fact of the Underwoods’ success presents a significant problem for all of us, since it changes the question from “How do real-world democratic politicians differ from the Underwoods?” to the much-more-difficult “What’s so great about democracy in the first place?”. (shrink)

To the general reader and watcher of television programmes medical ethics may appear to be something new. This is not so, for hundreds of articles and many books have appeared over the last 10 years or so to discuss and analyse the problems arising from the practice of medicine. In this study of two larger works - Medical Ethics and Manipulation - both by Bernard Häring, a Roman Catholic theologian - Father Brendan Soane analyses these in some detail and (...) sets their ideas in the context of what has already been written on the major issues of medical ethics and what is likely to be foremost in discussion in the near future. Many readers of this Journal already have the particular background of knowledge to see the problems in medicine which are in fact ethical but the general reader may require help and enlightenment and this is now provided for a special field within the field. (shrink)

Cognitive Science, Volume 46, Issue 4, April 2022.

In the 2016 film Doctor Strange, the title character undergoes a radical transition from successful neurosurgeon to highly skilled sorcerer. Unsurprisingly, he finds this transition difficult, in no small part because he thinks that sorcery seems somehow “unscientific.” Nevertheless, he eventually comes to adopt sorcery as wholeheartedly as he had embraced medicine. Some of his reasons for making this transition are personal, such as his desire to fix his injured hands and, later, to help others. Strange also displays the same (...) sorts of motivations that might drive any scientist: his intellectual curiosity drives him to understand how the Ancient One cured a paraplegic, and his desire to make a positive difference leads him to push the boundaries of sorcery. -/- This chapter will examine what Strange’s transition can teach us about the nature of scientific inquiry. More specifically, we’ll think about when it might make sense for scientists like Dr. Strange to change their approach. This will also allow us to explore what it means to practice science more generally. Some of what we learn might be surprising. For example, while it might seem obvious to us (and maybe even to Strange) that sorcery can’t count as a science, there are reasons for doubting this quick conclusion, at least in the sort of world that Dr. Strange lives in. Finally, we’ll consider what all of this means for science in our world, where things differ quite significantly. (shrink)

Charles Darwin famously argued that that life on earth was not the product of intelligent design, and that it instead had arisen through the entirely natural of process of evolution via natural selection. Darwin’s theory of evolution (together with Mendel’s theory of genetics) now forms the foundation of all the biological sciences. Jurassic Park, however, raises an interesting question: just how does Darwin’s theory apply to lifeforms that are the products of explicit, intelligent design? In this essay, I examine cluster (...) of issues in the philosophy of biology that turn out to be central in figuring out the answer to this question. Among other things, I discuss the difficulties in drawing sharp boundaries biological systems and non-biological systems, and between the products of natural selection and those of artificial selection. I also consider more generally how the process of evolution via natural selection is changed when intelligent agents begin to directly manipulate genetic material. (shrink)

For years a debate has raged within the various literatures of philosophy, psychiatry, and psychology over whether, and to what degree, the concepts that characterize psychopathology are social constructions that reflect cultural values. While the majority position among philosophers has been normativist, i.e., that the conception of a mental disorder is value-laden, a vocal and cogent minority have argued that psychopathology results from malfunctions that can be described by terminology that is objective and scientific. Scientists and clinicians have tended to (...) endorse the objectivist position, with some notable exceptions. (shrink)

The metaphor of scaffolding has become current in discussions of the cognitive help we get from artefacts, environmental affordances and each other. Consideration of mathematical tools and representations indicates that in these cases at least (and plausibly for others), scaffolding is the wrong picture, because scaffolding in good order is immobile, temporary and crude. Mathematical representations can be manipulated, are not temporary structures to aid development, and are refined. Reflection on examples from elementary algebra indicates that Menary is on the (...) right track with his ‘enculturation’ view of mathematical cognition. Moreover, these examples allow us to elaborate his remarks on the uniqueness of mathematical representations and their role in the emergence of new thoughts. (shrink)

In its original form, Nozick’s experience machine serves as a potent counterexample to a simplistic form of hedonism. The pleasurable life offered by the experience machine, its seems safe to say, lacks the requisite depth that many of us find necessary to lead a genuinely worthwhile life. Among other things, the experience machine offers no opportunities to establish meaningful relationships, or to engage in long-term artistic, intellectual, or political projects that survive one’s death. This intuitive objection finds some support in (...) recent research regarding the psychological effects of phenomena such as video games or social media use. After a brief discussion of these problems, I will consider a variation of the experience machine in which many of these deficits are remedied. In particular, I’ll explore the consequences of a creating a virtual world populated with strongly intelligent AIs with whom users could interact, and that could be engineered to survive the user’s death. The presence of these agents would allow for the cultivation of morally significant relationships, and the world’s long-term persistence would help ground possibilities for a meaningful, purposeful life in a way that Nozick’s original experience machine could not. While the creation of such a world is obviously beyond the scope of current technology, it represents a natural extension of the existing virtual worlds provided by current video games, and it provides a plausible “ideal case” toward which future virtual worlds will move. While this improved experience machine would seem to represent progress over Nozick’s original, I will argue that it raises a number of new problems stemming from the fact that that the world was created to provide a maximally satisfying and meaningful life for the intended user. This, in turn, raises problems analogous in some ways to the problem(s) of evil faced by theists. In particular, I will suggest that it is precisely those features that would make a world most attractive to potential users—the fact that the AIs are genuinely moral agents whose well-being the user can significantly impact—that render its creation morally problematic, since they require that the AIs inhabiting the world be subject to unnecessary suffering. I will survey the main lines of response to the traditional problem of evil, and will argue that they are irrelevant to this modified case. I will close by considering by consider what constraints on the future creation of virtual worlds, if any, might serve to allay the concerns identified in the previous discussion. I will argue that, insofar as the creation of such worlds would allow us to meet morally valuable purposes that could not be easily met otherwise, we would be unwise to prohibit it altogether. However, if our processes of creation are to be justified, they must take account of the interests of the moral agents that would come to exist as the result of our world creation. (shrink)

Evidence-based medicine (EBM) makes use of explicit procedures for grading evidence for causal claims. Normally, these procedures categorise evidence of correlation produced by statistical trials as better evidence for a causal claim than evidence of mechanisms produced by other methods. We argue, in contrast, that evidence of mechanisms needs to be viewed as complementary to, rather than inferior to, evidence of correlation. In this paper we first set out the case for treating evidence of mechanisms alongside evidence of correlation in (...) explicit protocols for evaluating evidence. Next we provide case studies which exemplify the ways in which evidence of mechanisms complements evidence of correlation in practice. Finally, we put forward some general considerations as to how the two sorts of evidence can be more closely integrated by EBM. (shrink)

English mass noun phrases & count noun phrases differ only minimally grammatically. The basis for the difference is ascribed to a difference in the features +/-CT. These features serve the morphosyntactic function of determining the available options for the assigment of grammatical number, itself determined by the features +/-PL: +CT places no restriction on the available options, while -CT, in the unmarked case, restricts the available options to -PL. They also serve the semantic function of determining the sort of denotation (...) associated with demonstrative & quantified noun phrases. The feature -CT requires that the associated denotation be the set whose sole member is the greatest aggregate of which the noun phrase or noun is true; the feature +CT requires that the associated denotation be the set whose members are all & only those minimal aggregates of which the noun phrase or noun is true. At the same time, neither mass NPs nor count NPs that are arguments of a predicate have their predicate evaluated with respect to their denotations. Rather, the predicate is evaluated with respect to an aggregation, a set of aggregates constructed from the denotation of the noun phrase that is an argument of the predicate. 3 Tables, 4 Figures, 74 References. AA. (shrink)

This book illustrates the profound implications of Gabriel Marcel's unique existentialist approach to epistemology not only for traditional themes in his work concerning ethics and the transcendent, but also for epistemological issues, concerning the objectivity of knowledge, the problem of skepticism, and the nature of non-conceptual knowledge, among others. There are also chapters of dialogue with philosophers, Jacques Maritain and Martin Buber. In focusing on these themes, the book makes a distinctive contribution to the literature on Marcel.Brendan Sweetman, a (...) native of Dublin, Ireland, is Professor of Philosophy at Rockhurst University, Kansas City, MO, USA. His books include Why Politics Needs Religion: The Place of Religious Arguments in the Public Square (InterVarsity, 2006) and Religion: Key Concepts in Philosophy (Continuum Books, 2007). He has coauthored or coedited several other books, including Truth and Religious Belief (M.E. Sharpe, 1998), and Contemporary Perspectives on Religious Epistemology (Oxford University Press, 1992). Professor Sweetman has published more than fifty articles and reviews in a variety of collections and journals, including International Philosophical Quarterly, American Catholic Philosophical Quarterly, Faith and Philosophy, Philosophia Christi, and Review of Metaphysics. He writes regularly in the areas of continental philosophy, philosophy of religion, political philosophy and ethics. (shrink)

Category theory reveals commonalities between structures of all sorts. This book shows its potential in science, engineering, and beyond.

Across worlds and bodies -- Touching the looking glass -- With thumbs in mind -- To touch sights and sounds -- Repetition, failure, and permanence -- From hackers to cyborgs.

Brendan Wilson leads the reader through Wittgenstein's Philosophical Investigations, revealing a new clarity, singleness of purpose and contemporary relevance in this acknowledged masterpiece.

What accounts for the capacity of ordinary speakers to comprehend utterances of their language? The phenomenology of hearing speech in one’s own language makes it tempting to many epistemologists to look to perception for an answer to this question. That is, just as a visual experience as of a red square is often taken to give the perceiver immediate justification for believing that there is a red square in front of her, perhaps an auditory experience as of the speaker asserting (...) that p gives the competent hearer immediate justification for believing that the speaker has asserted that p. My aim here is to offer reasons for resisting this temptation. I argue that the perceptual model cannot adequately account for the hearer’s justification in many cases. The arguments here also allow us to draw certain further morals about the role of phenomenology in the epistemology of perception. (shrink)

Daly, Brendan A famous case involving the seal of confession was that of Father Francis Douglas. In 1938, a New Zealand Columban priest, Father Francis Douglas was appointed to Pililla, a town near Manila in the Philippines. It was a difficult assignment, made worse by the Japanese occupation of the country in January 1942. In July 1943 he was asked to visit some guerrillas who said that they needed his priestly services. Afterwards, the Japanese then thought he was a (...) spy. He was tortured for 3 days and presumably killed because among other things he would not break the seal of confession. Many regard him as a martyr for being faithful to his priestly obligations. (shrink)

The metaphor of scaffolding has become current in discussions of the cognitive help we get from artefacts, environmental affordances and each other. Consideration of mathematical tools and representations indicates that in these cases at least, scaffolding is the wrong picture, because scaffolding in good order is immobile, temporary and crude. Mathematical representations can be manipulated, are not temporary structures to aid development, and are refined. Reflection on examples from elementary algebra indicates that Menary is on the right track with his (...) ‘enculturation’ view of mathematical cognition. Moreover, these examples allow us to elaborate his remarks on the uniqueness of mathematical representations and their role in the emergence of new thoughts. (shrink)

Over 115 000 people are waiting for life-saving organ transplants, of whom a small fraction will receive transplants and many others will die while waiting. Existing efforts to expand the number of available organs, including increasing the number of registered donors and procuring organs in uncontrolled environments, are crucial but unlikely to address the shortage in the near future and will not improve donor/recipient compatibility or organ quality. If successful, organ bioengineering can solve the shortage and improve functional outcomes. Studying (...) manufactured organs in animal models has produced valuable data, but is not sufficient to understand viability in humans. Before risking manufactured organ experimentation in living humans, study of bioengineered organs in recently deceased humans would facilitate evaluation of the function of engineered tissues and the complex interactions between the host and the transplanted tissue. Although such studies do not pose risk to human subjects, they pose unique ethical challenges concerning the previous wishes of the deceased, rights of surviving family members, effective operation and fair distribution of medical services, and public transparency. This article investigates the ethical, legal and social considerations in performing engineered organ research on the recently deceased. (shrink)

Internalists and externalists disagree over how intimately normative judgment and motivation are linked. Proponents on both sides typically try to settle the issue by descriptively interpreting our concept of a normative judgment. Unfortunately, this approach has resulted in deep and apparently intractable disagreement. It is time to consider alternative strategies. In this paper, I argue that the internalist/externalist debate is particularly ripe for revisionary arguments that evaluate conceptions of normative judgment in light of the costs and benefits of their adoption. (...) I then develop a revisionary case for externalism by identifying three practical hazards that come with internalist conceptions of normative judgment. Along the way, I show how these internalist hazards are mirrored by externalist benefits. I also argue that two potential benefits of internalism are not very beneficial. Together, these considerations give us strong practical reasons to adopt externalist conceptions of normative judgment, regardless of which account is descriptively accurate. (shrink)

A central source of support for expressivist accounts of normative discourse is the intimate relationship between normative judgment and motivation. Expressivists argue that normative judgments must be noncognitive, desire-like states in order to be so tightly linked with motivation. Normative statements are then construed as expressions of these noncognitive states. In this paper, I draw on dual-process models in cognitive psychology to respond to this argument. According to my proposal, normative judgments are ordinary beliefs that are typically produced by two (...) kinds of process: intuitive-affective processes and domain-general reasoning. When produced by the first kind of process, motivation and judgment tend to align. When produced by the second kind, motivation and judgment might not align. Since the first kind of process is the most common pathway of normative belief formation, normative judgments are typically accompanied by aligning motivation. This proposal enables cognitivists to explain the intimate link between normative judgment and motivation, thereby removing the major obstacle to interpreting normative statements truth-conditionally. (shrink)

Commentary on our target article centers around six main topics: (1) strategies in modeling the neurobehavioral foundation of human behavioral traits; (2) clarification of the construct of affiliation; (3) developmental aspects of affiliative bonding; (4) modeling disorders of affiliative reward; (5) serotonin and affiliative behavior; and (6) neural considerations. After an initial important research update in section R1, our Response is organized around these topics in the following six sections, R2 to R7.

The commentaries on our target article address three main areas: (1) the relative importance of extraversion and other related traits to DA functioning, (2) how the long-term stability of extraversion can be conceptualized within a highly plastic central nervous system, and (3) the nature of DA functioning in the MOC network and in extraversion. We have organized our Response, therefore, into three major sections.

This collection presents significant contributions from an international network project on mathematical cultures, including essays from leading scholars in the history and philosophy of mathematics and mathematics education.​ Mathematics has universal standards of validity. Nevertheless, there are local styles in mathematical research and teaching, and great variation in the place of mathematics in the larger cultures that mathematical practitioners belong to. The reflections on mathematical cultures collected in this book are of interest to mathematicians, philosophers, historians, sociologists, cognitive scientists and (...) mathematics educators. (shrink)

The view that a mathematical proof is a sketch of or recipe for a formal derivation requires the proof to function as an argument that there is a suitable derivation. This is a mathematical conclusion, and to avoid a regress we require some other account of how the proof can establish it.

One way to challenge the substantiveness of a particular philosophical issue is to argue that those who debate the issue are engaged in a merely verbal dispute. For example, it has been maintained that the apparent disagreement over the mind/brain identity thesis is a merely verbal dispute, and thus that there is no substantive question of whether or not mental properties are identical to neurological properties. The goal of this paper is to help clarify the relationship between mere verbalness and (...) substantiveness. I first argue that we should see mere verbalness as a certain kind of discourse defect that arises when the parties differ as to what each takes to be the immediate question under discussion. I then argue that mere verbalness, so understood, does not imply that the question either party is attempting to address is a non-substantive one. Even if it turns out that the parties to the mind/brain dispute are addressing subtly different questions, these might both be substantive questions to which their respective metaphysical views provide substantive answers. One reason it is tempting to reach deflationary conclusions from the charge of mere verbalness is that we fail to distinguish it from the claim that a sentence under dispute is, in a certain sense, indisputable. Another reason is that we fail to distinguish mere verbalness from a certain sort of indeterminacy. While indisputability and indeterminacy plausibly capture forms of nonsubstantiveness, I argue that mere verbalness is insufficient to establish either indisputability or indeterminacy. (shrink)