Background The Regional Committee for Africa of the World Health Organization (WHO) in 2001 expressed concern that some health-related studies undertaken in the Region were not subjected to any form of ethics review. In 2003, the study reported in this paper was conducted to determine which Member country did not have a national research ethics committee (REC) with a view to guiding the WHO Regional Office in developing practical strategies for supporting those countries. Methods This is a descriptive study. The (...) questionnaire was prepared and sent by diplomatic pouch to all the 46 Member States in the WHO African Region, through the WHO country representatives, for facilitation and follow up. The data were entered in Excel spreadsheet and subsequently exported to STATA for analysis. A Chi-Squared test (χ 2) for independence was undertaken to test the relationship between presence/absence of Research Ethics Committee (REC) and selected individual socioeconomic and health variables. Results The main findings were as follows: the response rate was 61% (28/46); 64% (18/28) confirmed the existence of RECs; 36% (10/28) of the respondent countries did not have a REC (although 80% of them reported that they had in place an ad hoc ethical review mechanism); 85% (22/26) of the countries that responded to this question indicated that ethical approval of research proposals was, in principle, required; and although 59% of the countries that had a REC expected it to meet every month, only 44% of them reported that the REC actually met on a monthly basis. In the Chi-Squared test, only the average population in the group of countries with a REC was statistically different (at 5% level of significance) from that of the group of countries without a REC. Conclusion In the current era of globalized biomedical research, good ethics stewardship demands that every country, irrespective of its level of economic development, should have in place a functional research ethics review system in order to protect the dignity, integrity and safety of its citizens who participate in research. (shrink)
Charles Darwin's On the Origin of Species is unquestionably one of the chief landmarks in biology. The Origin (as it is widely known) was literally only an abstract of the manuscript Darwin had originally intended to complete and publish as the formal presentation of his views on evolution. Compared with the Origin, his original long manuscript work on Natural Selection, which is presented here and made available for the first time in printed form, has more abundant examples and illustrations (...) of Darwin's argument, plus an extensive citation of sources. (shrink)
On 27th December 1831, HMS Beagle set out from Plymouth under the command of Captain Robert Fitzroy on a voyage that lasted nearly 5 years. The purpose of the trip was to complete a survey of the southern coasts of South America, and afterwards to circumnavigate the globe. The ship's geologist and naturalist was Charles Darwin. Darwin kept a diary throughout the voyage in which he recorded his daily activities, not only on board the ship but also during the (...) several long journeys that he made on horseback in Patagonia and Chile. His entries tell the story of one of the most important scientific journeys ever made with matchless immediacy and vivid descriptiveness. (shrink)
This is the first comprehensive evaluation of Charles Taylor's work and a major contribution to leading questions in philosophy and the human sciences as they face an increasingly pluralistic age. Charles Taylor is one of the most influential contemporary moral and political philosophers: in an era of specialisation he is one of the few thinkers who has developed a comprehensive philosophy which speaks to the conditions of the modern world in a way that is compelling to specialists in (...) various disciplines. This collection of specially commissioned essays brings together twelve distinguished scholars from a variety of fields to discuss critically Taylor's work. The topics range from the history of philosophy, to truth, modernity and postmodernity, theism, interpretation, the human sciences, liberalism, pluralism and difference. Taylor responds to all the contributions and re-articulates his own views. (shrink)
The PEIRCE EDITION contains large sections of previously unpublished material in addition to selected published works. Each volume includes a brief historical and biographical introduction, extensive editorial and textual notes, and a full chronological list of all of Peirce’s writings, published and unpublished, during the period covered.
[David Charles] Aristotle, it appears, sometimes identifies well-being with one activity, sometimes with several, including ethical virtue. I argue that this appearance is misleading. In the Nicomachean Ethics, intellectual contemplation is the central case of human well-being, but is not identical with it. Ethically virtuous activity is included in human well-being because it is an analogue of intellectual contemplation. This structure allows Aristotle to hold that while ethically virtuous activity is valuable in its own right, the best life available (...) for humans is centred around, but not wholly constituted by, intellectual contemplation. /// [Dominic Scott] In Nicomachean Ethics X 7-8, Aristotle distinguishes two kinds of eudaimonia, primary and secondary. The first corresponds to contemplation, the second to activity in accordance with moral virtue and practical reason. My task in this paper is to elucidate this distinction. Like Charles, I interpret it as one between paradigm and derivative cases; unlike him, I explain it in terms of similarity, not analogy. Furthermore, once the underlying nature of the distinction is understood, we can reconcile the claim that paradigm eudaimonia consists just in contemplation with a passage in the first book requiring eudaimonia to involve all intrinsic goods. (shrink)
Physicist, mathematician, and logician Charles S. Peirce was America's first internationally recognized philosopher, the man who created the concept of "pragmatism," later popularized by William James. Charles S. Peirce: The Essential Writings is a comprehensive collection of the philosopher's writings, including: "Questions Concerning Certain Faculties Claimed for Man", which outlines his theory of knowledge; a review of the works of George Berkeley; papers from between 1877 and 1905 developing the ground of pragmatism and Peirce's theory of scientific inquiry; (...) his basic concept of metaphysics ; and the important 1902 articles in Baldwin's dictionary on his later pragmatism, uniformity, and synechism. Included are Peirce's well-known essays: "The Fixation of Belief" and "How to Make Our Ideas Clear." Book jacket. (shrink)
Physicist, mathematician, and logician Charles S. Peirce (1839-1914) was America's first internationally recognized philosopher, the man who created the concept of "pragmatism," later popularized by William James. Charles S. Peirce: The Essential Writings is a comprehensive collection of the philosopher's writings, including: "Questions Concerning Certain Faculties Claimed for Man" (1868), which outlines his theory of knowledge; a review of the works of George Berkeley; papers from between 1877 and 1905 developing the ground of pragmatism and Peirce's theory of (...) scientific inquiry; his basic concept of metaphysics (1891-93); and the important 1902 articles in Baldwin's dictionary on his later pragmatism (or pragmaticism), uniformity, and synechism. Included are Peirce's well-known essays: "The Fixation of Belief" and "How to Make Our Ideas Clear." Book jacket. (shrink)
This interview with Charles Taylor explores a central concern throughout his work, namely, his concern to ‘reenchant’ self and world through a careful examination of value as emanating from the world rather than from ourselves. It focuses especially on the status of his central doctrine of ‘strong evaluation’ against the background of mainstream meta-ethical theories, such as neo-Kantian constructivism and robust realist non-naturalism. Additionally, the relationship between Taylor’s theism and his moral–political philosophy is discussed. A key issue that is (...) examined is what ontological background picture can make sense of the strong evaluative experience of higher worth. Some other related issues that are explored revolve around Taylor’s papers ‘Disenchantment-Reenchantment’ and ‘Recovering the Sacred’, which tentatively explore the meaning of reenchantment. (shrink)
The law tends to think that there is no difficulty about identifying humans. When someone is born, her name is entered into a statutory register. She is ‘X’ in the eyes of the law. At some point, ‘X’ will die and her name will be recorded in another register. If anyone suggested that the second X was not the same as the first, the suggestion would be met with bewilderment. During X's lifetime, the civil law assumed that the X who (...) entered into a contract was the same person who breached it. The criminal law assumed that X, at the age of 80, was liable for criminal offences ‘she’ committed at the age of 18. This accords with the way we talk. ‘She's not herself today’, we say; or ‘When he killed his wife he wasn't in his right mind’. The intuition has high authority: ‘To thine own self be true’, urged Polonius.1 It sounds as if we believe in souls—immutable, core essences that constitute our real selves. Medicine conspires in the belief. If you become mentally ill, a psychiatrist will seek to get you back to your right mind. The Mental Capacity Act 1985 states that when a patient loses capacity the only lawful interventions will be interventions which are in that patient's best interests,2 and that in determining what those interests are the decision-maker must have …. (shrink)
Familiarity with Charles Darwin's treatise on evolution is essential to every well-educated individual. One of the most important books ever published--and a continuing source of controversy, a century and a half later--this classic of science is reproduced in a facsimile of the critically acclaimed first edition.
Are they needed? To be sure. The Darwinian industry, industrious though it is, has failed to provide texts of more than a handful of Darwin's books. If you want to know what Darwin said about barnacles (still an essential reference to cirripedists, apart from any historical importance) you are forced to search shelves, or wait while someone does it for you; some have been in print for a century; various reprints have appeared and since vanished." -Eric Korn,Times Literary Supplement (...) class='Hi'>Charles Robert Darwin (1880-1882) has been widely recognized since his own time as one of the most influential writers in the history of Western thought. His books were widely read by specialists and the general public, and his influence had been extended by almost continuous public debate over the last 130 years. New York University Press' edition makes it possible for the first time to review Darwin's public literary output as a whole, plus his scientific journal articles, his private notebooks, and his correspondence. This is the first complete edition containing all of Darwin's published books, featuring definitive texts recording original paginations with Darwin's indexes retained. All illustrations and plates are presented, inclucing 82 color plates of birds and mammals and several folding maps and plates. The set also features a general introduction and index, and textural introductions in each volume. (shrink)
This volume is a Festschrift dedicated to Charles Kahn comprised of more than 20 papers presented at the conference "Presocratics and Plato: Festschrift Symposium in Honor of Charles Kahn", 3-7 June 2009. The conference was held at the European Cultural Center of Delphi, Greece, and was organized and sponsored by the HYELE Institute for Comparative Studies and Parmenides Publishing, with endorsement from the International Plato Society, and the Dean of the School of Arts and Sciences, University of Pennsylvania. (...) Contributors: Julia Annas - University of Arizona; Sarah Broadie - University of St. Andrews; Lesley Brown - University of Oxford; Tomás Calvo-Martínez - Universidad Complutense de Madrid; Diskin Clay - Duke University; John M. Dillon - Trinity College, Dublin; Dorothea Frede - Humbolt University, Berlin; Arnold Hermann - HYELE Institute for Comparative Studies; Carl A. Huffman - DePauw University; Enrique Hülsz Piccone - Universidad Nacional Autonoma de Mexico; D.M. Hutchinson - St. Olaf College; Paul Kalligas - National and Kapodistrian University, Athens; Vassilis Karasmanis - National Technical University, Athens; Aryeh Kosman - Haverford College; Anthony A. Long - University of California, Berkeley; Richard McKirahan - Pomona College; Susan Sauvé Meyer - University of Pennsylvania; Alexander P.D. Mourelatos - University of Texas at Austin; Satoshi Ogihara - Tohoku University, Japan; Richard Patterson - Emory University; Christopher J. Rowe - Durham University; David Sedley - University of Cambridge; Richard Sorabji - University of Oxford. (shrink)
: In response to the preceding commentary by Jerry Menikoff in this issue of the Journal , the authors argue that Fried's central concern is not that randomized clinical trials (RCTs) are conducted without consent, but rather that various aspects of the design and conduct of RCTs are in tension with physicians' duties of personal care to their patients. Although Fried does argue that the existence of equipoise cannot justify failure to obtain consent from research subjects, informed consent by itself (...) does not supplant ill subjects' rights to personalized judgment and care embodied in Fried's equipoise. (shrink)
Charles Taylor’s idea of “deep diversity” has played a major role in the debates around multiculturalism in Canada and around the world. Originally, the idea was meant to account for how the different national communities within Canada – those of the English-speaking Canadians, the French-speaking Quebeckers, and the Aboriginals – conceive of their belonging to the country in different ways. But Taylor conceives of these differences strictly in terms of irreducibility; that is, he fails to see that they also (...) exist in such a way that the country cannot be said to form a unified whole. After giving an account of the philosophical as well as religious reasons behind his position, the chapter goes on to describe some of its political implications. (shrink)
David Charles presents a major new study of Aristotle's views on meaning, essence, necessity, and related topics. These interconnected views are central to Aristotle's metaphysics, philosophy of language, and philosophy of science, and are also highly relevant to current philosophical debates. Charles aims to reach a clear understanding of Aristotle's claims and arguments, to assess their truth, and to evaluate their importance to ancient and modern philosophy.
This transcription of notes made by Charles Darwin during the voyage of H. M. S. Beagle records his observations of the animals and plants that he encountered, and provides a valuable insight into the intellectual development of one of our most influential scientists. Darwin drew on many of these notes for his well known Journal of Researches (1839), but the majority of them have remained unpublished. This volume provides numerous examples of his unimpeachable accuracy in describing the wide range (...) of animals seen in the course of his travels, and of his closely analytical approach towards every one of his observations. Only at the very end of the voyage were his first doubts about the immutability of species expressed consciously, but here are to be found the initial seeds of his theory of evolution, and of the fields of behavioural and ecological study of which he was one of the founding fathers. (shrink)
"For anyone seriously interested in Peirce, or in nineteenth-century American philosophy, or in American intellectual history, or in philosophy in general, or in semiotics and its philosophical import, these volumes should be required reading." —Murray G. Murphey, Semiotica.
In The Origin of Species (1859) Darwin challenged many of the most deeply-held beliefs of the Western world. Arguing for a material, not divine, origin of species, he showed that new species are achieved by "natural selection." The Origin communicates the enthusiasm of original thinking in an open, descriptive style, and Darwin's emphasis on the value of diversity speaks more strongly now than ever. As well as a stimulating introduction and detailed notes, this edition offers a register of the many (...) writers referred to by Darwin in the text. (shrink)
Perhaps the most readable and accessible of the great works of scientific imagination, The Origin of Species sold out on the day it was published in 1859. Theologians quickly labeled Charles Darwin the most dangerous man in England, and, as the Saturday Review noted, the uproar over the book quickly "passed beyond the bounds of the study and lecture-room into the drawing-room and the public street." Yet, after reading it, Darwin's friend and colleague T. H. Huxley had a different (...) reaction: "How extremely stupid not to have thought of that." Based largely on Darwin's experience as a naturalist while on a five-year voyage aboard H.M.S. Beagle, The Origin of Species set forth a theory of evolution and natural selection that challenged contemporary beliefs about divine providence and the immutability of species. A landmark contribution to philosophical and scientific thought, this edition also includes an introductory historical sketch and a glossary Darwin later added to the original text. Charles Darwin grew up considered, by his own account, "a very ordinary boy, rather below the common standard of intellect." A quirk of fate kept him from the career his father had deemed appropriate--that of a country parson--when a botanist recommended Darwin for an appointment as a naturalist aboard H.M.S. Beagle from 1831 to 1836. Darwin is also the author of the five-volume work Zoology of the Voyage of the Beagle (1839) and The Descent of Man (1871). (shrink)