Tetrahymena has been used as a model cell system in many studies of morphogenesis, conjugation, gene mapping, cell division and growth kinetics. In this article, we consider some advances which have resulted from the successful development of a chemically defined medium (CDM), and how subsequent work has extended the contribution that this organism has made to our understanding of different aspects of growth, nutrition, cell cycle control, cytokinesis and intercellular signalling. Finally, we discuss the considerable potential that has arisen for (...) the biotechnological exploitation of this big and rapidly growing eukaryotic cell. (shrink)

The paper argues that the final value of an object-i.e., its value for its own sake-need not be intrinsic. Extrinsic final value, which accrues to things (or persons) in virtue of their relational rather than internal features, cannot be traced back to the intrinsic value of states that involve these things together with their relations. On the contrary, such states, insofar as they are valuable at all, derive their value from the things involved. The endeavour to reduce thing-values to state-values (...) is largely motivated by a mistaken belief that appropriate responses to value must consist in preferring and/or promoting. A pluralist approach to value analysis obviates the need for reduction: the final value of a thing or person can be given an independent interpretation in terms of the appropriate thing- or person-oriented responses: admiration, love, respect, protection, care, cherishing, etc. (shrink)

The paper argues that the final value of an object-i.e., its value for its own sake-need not be intrinsic. Extrinsic final value, which accrues to things in virtue of their relational rather than internal features, cannot be traced back to the intrinsic value of states that involve these things together with their relations. On the contrary, such states, insofar as they are valuable at all, derive their value from the things involved. The endeavour to reduce thing-values to state-values is largely (...) motivated by a mistaken belief that appropriate responses to value must consist in preferring and/or promoting. A pluralist approach to value analysis obviates the need for reduction: the final value of a thing or person can be given an independent interpretation in terms of the appropriate thing- or person-oriented responses: admiration, love, respect, protection, care, cherishing, etc. (shrink)

The authors of this paper earlier argued that concrete objects, such as things or persons, may have final value (value for their own sake), which is not reducible to the value of states of affairs that concern the object in question.Our arguments have been challenged. This paper is an attempt to respond to some of these challenges, viz. those that concern the reducibility issue. The discussion presupposes a Brentano‐inspired account of value in terms of fitting responses to value bearers. Attention (...) is given to a yet another type of reduction proposal, according to which the ultimate bearers of final value are abstract particulars (so‐called tropes) rather than abstract states or facts. While the proposal is attractive ((fone entertains the existence of tropes), it confronts serious difficulties. To recognise tropes as potential bearers of final value, along with other objects, is one thing; but to reduce the final value of concrete objects to the final value of tropes is another matter. (shrink)

The authors of this paper earlier argued that concrete objects, such as things or persons, may have final value , which is not reducible to the value of states of affairs that concern the object in question.Our arguments have been challenged. This paper is an attempt to respond to some of these challenges, viz. those that concern the reducibility issue. The discussion presupposes a Brentano-inspired account of value in terms of fitting responses to value bearers. Attention is given to a (...) yet another type of reduction proposal, according to which the ultimate bearers of final value are abstract particulars rather than abstract states or facts. While the proposal is attractive , it confronts serious difficulties. To recognise tropes as potential bearers of final value, along with other objects, is one thing; but to reduce the final value of concrete objects to the final value of tropes is another matter. (shrink)

The paper presents main conceptual distinctions underlying much of modern philosophical thinking about value. The introductory Section 1 is followed in Section 2 by an outline of the contrast between non-relational value and relational value. In Section 3, the focus is on the distinction between final and non-final value as well as on different kinds of final value. In Section 4, we consider value relations, such as being better/worse/equally good/on a par. Recent discussions suggest that we might need to considerably (...) extend traditional taxonomies of value relations. (shrink)

Digitalization is often associated with optimistic grand narratives about a future society in academic discourse. While the word is frequently linked with hopes and expectations of societal rebirth and beneficial changes for societies and organizations, there has been little attention given to systematically investigating the risks associated with digitalization. This paper aims to investigate the relationship between digitalization and risk, thereby characterizing “the digital risk society.” By conducting a narrative summary and thematic analysis of 34 academic papers three aggregated themes (...) were outlined: First, in the digital risk society, intangible technologies serve as solutions while simultaneously introducing new risks. Second, as an increasing number of tasks are delegated to machines with opaque inner functions, society is suffering from dehumanization. Third, scholars are calling for new approaches to govern these technologies, spurred by concerns over their potentially harmful use. (shrink)

forthcoming in Philosophy & Public Affairs [2008].

Rights dominate most modern understandings of what actions are proper and which institutions are just. Rights structure the forms of our governments, the contents of our laws, and the shape of morality as we perceive it. To accept a set of rights is to approve a distribution of freedom and authority, and so to endorse a certain view of what may, must, and must not be done.

The twentieth century saw a vigorous debate over the nature of rights. Will theorists argued that the function of rights is to allocate domains of freedom. Interest theorists portrayed rights as defenders of well-being. Each side declared its conceptual analysis to be closer to an ordinary understanding of what rights there are, and to an ordinary understand- ing of what rights do for rightholders. Neither side could win a decisive victory, and the debate ended in a standoff.

The paper presents main conceptual distinctions underlying much of modern philosophical thinking about value. The introductory Section 1 is followed in Section 2 by an outline of the contrast between non-relational value and relational value. In Section 3, the focus is on the distinction between final and non-final value as well as on different kinds of final value. In Section 4, we consider value relations, such as being better/worse/equally good/on a par. Recent discussions suggest that we might need to considerably (...) extend traditional taxonomies of value relations. (shrink)

What morality requires of us in a world of poverty and inequality depends both on what our duties are in the abstract, and on what we can do to help. T.M. Scanlon's contractualism addresses the first question. I suggest that contractualism isolates the moral factors that frame our deliberations about the extent of our obligations in situations of need. To this extent, contractualism clarifies our common-sense understanding of our duties to distant others. The second, empirical question then becomes vital. What (...) we as individuals need to know is how to fulfil our duties to the distant poor. Moral theorists tend to base their prescriptions on simple assumptions about how the rich can help the poor. Yet a survey of the empirical literature shows how urgently we need more information on this topic before we can know what contractualist morality — or any plausible morality — requires of us. Key Words: Scanlon • contractualism • global justice • global poverty • aid effectiveness. (shrink)

We investigate the value of persons. Our primary goal is to chart a path from equal and extreme value to infinite value. We advance two arguments. Each argument offers a reason to think that equal and extreme value are best accounted for if we are infinitely valuable. We then raise some difficult but fruitful questions about the possible grounds or sources of our infinite value, if we indeed have such value.

This chapter contains section titled: Justice as Fairness Rawls and the Cosmopolitan Egalitarians The Puzzle of Rawls's Rejection of Global Egalitarianism Rawls's Fundamental Norm of Legitimacy Why Rawls is not a Cosmopolitan Why Rawls is not a Global Egalitarian The Impossibility of Pure Cosmopolitanism Conclusion Notes.

justice as fairness envisions a society of free citizens holding equal basic rights cooperating within an egalitarian economic system. His account of political liberalism addresses the legitimate use of political power in a democracy, aiming to show how enduring unity may be achieved despite the diversity of worldviews that free institutions allow. His writings on the law of peoples extend these theories to liberal foreign policy, with the goal of imagining how a peaceful and tolerant international order might be possible.

Much fuss has been made of the “spatial turn” in recent years, across a range of disciplines. It is hard to know if the attention has been warranted. A confusion of terms has been used—such as space, place, spatiality, location—and each has signified a cluster of often contradictory and confusing meanings. This phenomenon is common to a range of disciplines in the humanities. This means, first, that it is not always easy to recognize what is being discussed under the rubric (...) of space, and second, that over-extended uses of the cultural turn have stymied meaningful engagement with materiality in discussions of space. This article shows how materiality has been marginalized both by a casual vocabulary and a vigorous a priori epistemological holism on the part of scholars, and how the spatial turn has been too closely linked to the cultural turn to allow it to develop its fullest explanatory potential. It demonstrates how historians might profitably theorize the significance of place and space in their work , and sets out some challenges for using space more effectively in explanatory systems. Inspired by environmental history, sociology, and science and technology studies, I propose a way of establishing space as different from conventional historical handling of materiality, and end by identifying some methodological problems that need to be solved if we are to proceed on a surer footing. (shrink)

Leif Wenar examines the impact on takings scholarship of the redefinition of "property" early in the twentieth century. He argues that the Hohfeldian characterization of property as rights (instead of as tangible things) forced major scholars such as Michelman, Sax, and Epstein into extreme interpretations of the Takings Clause. This extremism is unnecessary, however, since the original objections to the idea that "property is things" are mistaken.

Entrepreneurial agency—the individual power to change environments—is central to entrepreneurship research. Yet, from a social inequality perspective, beliefs in an entrepreneurial agency might differ based on the social class environments individuals are born into. Drawing on social cognitive theories, our findings across three data sets among students from Germany and entrepreneurs from the United States indicate that social class origins are associated with entrepreneurial self-efficacy (ESE) beliefs in adulthood. Exploring the underlying mechanisms, we find that students’ early entrepreneurial experiences in (...) education and practice are indicative of reproducing the class gap in ESE. When individuals collect mastery experiences such as social mobility or entrepreneurial success, their lower social class origins turn out to be associated with enhanced entrepreneurial agency beliefs. We discuss the implications for further research on social class, inequality, and entrepreneurship. (shrink)

Although Professor Lewin is not testing existing views that, for people in politics, 'egoism rules' on deep theoretical grounds, he strongly argues that empirical facts do not support such views and thus opens a new chapter in the debate on ...

This article examines Rawls's and Scanlon's surprisingly undemanding contractualist accounts of global moral principles. Scanlon's Principle of Rescue requires too little of the world's rich unless the causal links between them and the poor are unreliable. Rawls's principle of legitimacy leads him to theorize in terms of a law of peoples instead of persons, and his conception of a people leads him to spurn global distributive equality. Rawls's approach has advantages over the cosmopolitan egalitarianism of Beitz and Pogge. But it (...) cannot generate principles to regulate the entire global economic order. The article proposes a new cosmopolitan economic original position argument to make up for this lack in Rawls's Law of Peoples. (shrink)

This is a new analysis of rights, particularly of the paradigm: the claim-right. The new analysis makes better sense of rights than the leading alternatives do. The new analysis handles all of the well-known counterexamples to the Will and Interest theories; it seems not to generate counterexamples of its own; and it solves many long-standing puzzles in the theory of rights. Moreover, the central concepts of the new theory are as salient and forceful as are rights themselves.

Social interaction and the constitution of mediated and nested space in the court of appeal -- Conclusion -- Concluding remarks: On becoming juridical -- Ways of spacing law and politics -- Becoming juridical -- Towards hybrid juridical spaces -- References -- Index.

Recent research suggests that many microfinance institutions increasingly focus on financial performance at the expense of the social component of their dual objectives. Existing studies typically assume that capital providers and managers mainly drive this so-called mission drift. In this study, we investigate whether ‘personal mission drift’ at the credit officer level can further explain the reduced emphasis on poorer clients among microfinance institutions. We present both qualitative and quantitative evidence that more experienced credit officers tend to serve fewer vulnerable (...) clients. Specifically, we show that all else being equal, credit officer experience is negatively correlated with the provision of small loans, loans to young clients, and loans to clients with disabilities. Our qualitative analysis suggests that perceived client risk and preferences for increased time efficiency mainly drive more experienced credit officers’ relative neglect of more vulnerable clients. This drift appears to be reinforced by the industry’s incentive schemes. Therefore, credit officer incentives and training should be designed to prevent this mission drift, which is observed at the microfinance institution level but is actually initiated at the credit officer level. (shrink)

Journal of Political Philosophy, EarlyView.

In the Standard View, a blamee can dismiss another's blaming of her as hypocritical and thus standingless if, and only if, the blamer's violations of the norm he is invoking are as bad as the blamee's. I defend a counterexample to this view showing that blame can be hypocritical and thus standingless when, simultaneously with blaming, the blamer willingly violates, in a minor way, the norm he is invoking. If correct, this has important implications for accounts of what makes hypocritical (...) blame standingless. Hypocritical blame of the sort involved in my counterexample cannot be accommodated by the moral equality account of standing to blame. Nor can existing commitment accounts accommodate it without revising the way we think about standing-relevant commitment. Hence, this article points to a need for both revising the common view of when blame can be dismissed as hypocritical and rethinking the two standard accounts of that in virtue of which we have or lack standing to blame. Specifically, it points to an interesting way in which standing to blame appears to be time-relative. (shrink)

The community has legislatively conferred on external auditors a special but lucrative responsibility to provide fair and independent opinions about management''s preparation of company financial statements. In return, auditors are obliged by professional standards to act with integrity, independently and in the public interest. This study examined 174 auditors'' predisposition to provide just and fair judgements, using Kohlberg''s theory of developmental moral reasoning, one of the most widely accepted theories in justice psychology. Respondents came from five international audit firms in (...) Copenhagen. Results indicated that auditors with pre-conventional or low level of just reasoning or comprised 64 respondents, the largest group in the sample. The pre-conventional level suggests that people will act in their own self-interest and do the right only to avoid punishment. Pre-conventional auditors have the ability to "do deals", advantageous for business. When faced with an ethical crisis, however, auditors as this level will tend to focus on their own needs at the expense of others. The post-conventional or mid level of just reasoning comprised 59 auditors, second largest group in the sample. This level indicates that these auditors have the predisposition to act fairly on principal, particularly when faced with an ethical crisis. The conventional level or mid-just reasoning consisted of 51 auditors. People with a conventional level of just reasoning believe in law and order, the maintenance of the status quo, however they tend not to be critical of laws, nor authority even if those laws and authority are unjust or evil. (shrink)

Concerns over aid effectiveness have led to calls for greater accountability in international development aid. This article examines the state of accountability within and between international development agencies: aid NGOs, international financial institutions, and government aid ministries.

A Northern Ireland politician declared not long ago that the British people had a right not to believe the IRA’s latest statement on disarmament. Therefore, he said, the British government had no right to allow the IRA further representation at the talks. Rights assertions like these are quite common in everyday talk, even if pronouncements linking epistemic and legal rights are less so.

The resource curse impedes core interests of importing states, while the policies of these states drive the resource curse. These policies violate importing states' existing international commitments.

All of these claims for reparations have mobilized popular support, and all share a degree of intuitive plausibility. The challenge to the theorist is to judge whether and which of such demands are grounded in sound principles of political normativity, so as to be able to select out the valid claims and to measure how the urgency of these claims compares with other demands on the public agenda. The most basic question for those considering the justifications of reparations is how (...) to orient their theories within the space of reasons. Do valid claims for reparation rest at the deepest level on reasons we have for redressing a past injustice? Or do they rather rest on reasons we have to improve our current relations so that we can get along better in the future? Are valid reparative demands backward- or forward-looking? (shrink)

Philosophy &Public Affairs, Volume 51, Issue 3, Page 195-233, Summer 2023.