This intriguing new book examines and analyses the role of critical realism in economics and specifically how this line of thought can be applied to the real world. With contributions from such varying commentators as Sheila Dow, Wendy Olsen and Fred Lee, this new book is unique in its approach and will be of great interest to both economic methodologists and those involved in applied economic studies.

This intriguing new book examines and analyses the role of critical realism in economics and specifically how this line of thought can be applied to the real world. With contributions from such varying commentators as Sheila Dow, Wendy Olsen and Fred Lee, this new book is unique in its approach and will be of great interest to both economic methodologists and those involved in applied economic studies.

This book is an inquiry into the motivation for altruistic behavior. It uncovers the condition that prompts or sometimes even compels us to act intentionally for the benefit of others. This condition, the pre-reflective experience of another person as a self-conscious individual just like oneself, finds its origin in the very structure of the mind. The essay is a synthesis of evidence from neuroscience, phenomenology, Eastern philosophy, analytic philosophy of mind, and cognitive psychology. Hence, it is an excellent example of (...) work in applied cognitive science. The book includes a critique of the several main approaches to the explanation of the motivation for altruistic behavior: biological, psychological, and philosophical. The path of the main inquiry produces several innovative proposals in the philosophy of mind in addition to the main conclusion. Included in these are a detailed account of the structure of the human mind, an ontological categorization of mental states, a naturalistic explanation of so-called mystical states, a proposal for the role of consciousness in the downward causation of physical events, a new interpretation of the Buddhist doctrine of no-self and a unique view of the nature of love. (shrink)

A framework for representing a specific kind of emergent property instance is given. A solution to a generalized version of the exclusion argument is then provided and it is shown that upwards and downwards causation is unproblematical for that kind of emergence. One real example of this kind of emergence is briefly described and the suggestion made that emergence may be more common than current opinions allow.

In lieu of an abstract, here is a brief excerpt of the content:Ovid, Art, and Eros PAUL BAROLSKY OVIDIO, AMORI, miti e altre storie or Ovid: Loves, Myths, and Other Stories is the copiously illustrated catalogue to the monumental exhibition mounted in 2008–2009 at the Scuderie del Quirinale, in Rome, in celebration of the great Roman poet and his world. This handsome tome is many books in one: a beautiful album of color plates illustrating a wide range of fascinating (...) objects, an overview of Ovid’s life, works and influences—a book for amateurs and specialists alike, a book to delight and instruct. The book includes paintings and sculpture but also pottery, coins, and jewelry. There is something for everybody here. Ovidio is divided into relatively brief sections written by numerous scholars who treat such topics as Ovid and myth, Ovid the love poet, Ovid in exile, Ovid and Augustan Rome, Ovid and the figurative arts, and Ovid in the seventeenth century. The book’s attention to illustrated editions of Metamorphoses, and especially the Ovide moralisé, is notable and refreshing. I think it fair to say that the exhibition and its catalogue are, not surprisingly, dominated by Metamorphoses and the ways in which artists illustrated its stories over the centuries. The myths of Venus and Adonis, Narcissus and Echo, Icarus and Daedalus, and Jupiter and Europa are among the numerous Ovidian stories that get extensive treatment here. We need to recall that no ancient author in the Hellenic tradition is so copiously illustrated as is Ovid—a fact that is Ovidio, amori, miti e altre storie, ed Francesca Ghedini et al. Rome 2018, 310 pages; isbn 9788856906486; €33.15. arion 27.2 fall 2019 easily taken for granted. A consummate story teller, Ovid inspired the pictorial tales of Poussin, Rubens, Rembrandt, and Velázquez, among other masters. Often in this book, works of mythological art are seen in the context of Ovid, even when there is no specific association between image and text. Such is the case when, for example, we encounter the well-known Praxitelean Aphrodite pudica in the Uffizi which inspired Botticelli’s similar Aphrodite now in the Musei Reali of Turin. There is nothing that links the statue and the painting to Ovid other than the fact that their makers, like the poet, write about the goddess of love. Ever so many mythological works suggest the arousal of desire. The Praxitelean Aphrodite modestly covers her body with both of her hands. Understandably, since according to an ancient tale, a young man was so aroused by the statue that he left a stain upon her. In short, we are in the realm of erotic art. The Hellenistic statue of Leda and the Swan in the archeology museum of Venice is an excellent example of erotic art featured in this book, even though Leda is mentioned only in passing in Metamorphoses. She seems to swoon in rapture as the bird (Jupiter in avian guise) slithers between her legs, beak seeking lips. Scarcely resisting, Leda reaches ambiguously downward as if in search of something, and we can well imagine what that might be. That her lower hand is invisible contributes to its suggestiveness. Leda’s upper hand is pressed against the swan’s sinuous neck, by no means a gesture of resist170 ovid, art, and eros Figure 1: Leda and the Swan. Venice, Museo Archeologico Nazionale, 2018. Eric Vandeville / akg-images. ance, I believe, even though in the myth she is taken by force. What we see is what the Ovid catalogue calls a “voluptuous amplexus.” The story of Leda and the Swan is forever told by painters in various erotic ways. When, later in the Renaissance, Correggio pictures the momentous event he shows the swan mounting Leda who, in this case, receives the bird in a seated position. As the bird engages the nymph, feathers pressed against her inner thigh, the swan, as in the ancient statue, seeks out her mouth with his beak—a juxtaposition as phallic as it is oral. The Leonardesque smile of Leda betokens not fear or violence but pleasure—a decidedly carnal pleasure. In a different context, Vasari wrote that Correggio painted not colors but flesh. When Leonardo himself pictured Leda, he delicately rendered the... (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Reflections on Raphael PAUL BAROLSKY The essence of all appreciation and analysis of art is the translation of visual perceptions into compelling verbal form. —Ralph Lieberman cultural unity Horace Walpole, Sir Joshua Reynolds, Johann Wolfgang Goethe, Eugène Delacroix, Honoré Balzac, Friedrich Hegel, Charles Baudelaire, Friedrich Nietzsche, Pierre Renoir, Nathaniel Hawthorne, August Wilhelm von Schlegel, Heinrich von Kleist, Franz Grillparzer, Fyodor Dostoyevsky, Ivan Turgenev, Wilhelm Heinrich Wackenroder, George Eliot, (...) Jean-Auguste Dominique Ingres, Roger Fry, Bernard Berenson, Theodor Hetzer, Roberto Longhi, Heinrich Wölfflin, and Stendhal are among the many essayists, critics, novelists, poets, painters and art historians who have responded to Raphael’s work as painter, architect or archeologist over the centuries. I can well imagine all of those listed above, among many others, united in an imaginary painting similar to the School of Athens—in other words, a vision that reconciles their various views of the world in a harmony analogous to the unity of philosophers in Raphael’s great fresco. Raphael is a towering figure in the history of European culture. The year 2020 was the 500th anniversary of the death of the great painter in Rome at the age of thirty-seven. In the wake of recent exhibitions that commemorated the artist’s achievement, I propose to touch briefly and lightly on a few aspects arion 28.2 fall 2020 100 reflections on raphael of Raphael’s life and works. Please think of these remarks as a series of suggestions, not attempts at definitive interpretation. I think of this essay as a rather experimental piece. THE SCHOOL OF ATHENS i should like to begin with a few brief remarks on what must be Raphael’s most famous work of art. I mean his School of Athens (fig. 1), which is, like Leonardo’s Mona Lisa and Last Supper or like Michelangelo’s David and Creation of Adam, an image widely known and admired. What more is there to say about The School Of Athens, one of the central images in the Stanza della Segnatura? You might spend the rest of your life reading about this great work and never understand it fully. Nevertheless, I want to focus for a moment on a central detail of the work and, on the basis of my description, point to a significant aspect of the fresco that has been universally overlooked. First the description, then the aperçu. Fig. 1. School of Athens. Ca. 1510–1512. Photo Credit : Erich Lessing / Art Resource, NY. Paul Barolsky 101 At the center of the School of Athens we behold the two great philosophers of classical antiquity: Plato and Aristotle. Plato holds a copy of his Timaeus, a dialogue that concerns the harmony of the heavens; Aristotle holds a copy of his Ethics, a work that pertains to human relations in this world. It was the goal of Renaissance thinkers to create a harmony or concord of the thought of these philosophers: a Concordia Platonis et Aristotelis. Raphael’s fresco, as is well known, presents the visual ideal of such harmony. Whereas Aristotle gestures downward, alluding to this world, in which his Ethics matter, Plato points heavenward, evoking the order of the cosmic realm described in Timaeus. Raphael makes visible the ideal of concordia when he movingly pictures the way in which the two philosophers gaze into each other’s eyes, as if to suggest this harmony. Borrowing from the language of Raphael ’s friend, Baldassare Castiglione, Raphael renders “the joining” of their souls. The monumental architecture of the scene, which echoes Bramante and has taproots in Piero della Francesca and Perugino, consists of three barrel-vaults beyond which we see patches of blue sky and puffs of cloud (fig. 2). The grandiose architecture of the image magnifies Raphael’s philosophers. Within this architectural framework, Plato’s gesture is deeply meaningful, since it prompts the viewer to look up and thus ascend toward the perfection of the celestial realm, beyond the imperfections of the physical world. Above the first barrel vault in the fresco we behold a section of the drum of a dome which is open to the sky. Within this section of drum there are two columns that are lined up directly... (shrink)

Seeing Nature is a series of true stories or parables that offer tools for understanding relationships in the natural world. Many of the stories take the reader to wild landscapes, including canyons, tundra, and mountain ridges, while others contemplate the human-made world: water-diversion trenches and supermarket check-out lines. At one point, Krafel discovers a world in a one-inch-square patch of ordinary ground. Inspiring for parents and teachers seeking to encourage excitement about the positive role of people in nature, Krafel's work (...) harkens to St. Exupery's The Little Prince, Annie Dillard's Pilgrim at Tinker Creek, and Jean Giono's The Man Who Planted Trees. As Barbara Damrosch has noted: [This book] is a gift.... With curiosity, wit, and a spare and graceful style, Krafel notes why birds in flocks land as they do, how islands can move upstream in a river, how kelp forests, swaying gently, break the force of the sea's power, how tundra plants create whole ecosystems on bare rock from mere specks of life. Yet there are no long-winded sermons about the woods, or cute anthropomorphizations of animals. The book's economical, unsentimental style is part of its originality. Paul Krafel's years as a park ranger afforded him time to walk and think--his job was to observe the world around him. He is now a teacher, creating a curriculum for young people that is built on a startlingly simple truth: The world around us is an extended conversation between "upward spirals"--nature in regenerative, procreative modes--and downward spirals toward entropy and disintegration. As nature refreshes and rebuilds, the downward spirals are overcome. Nature's process becomes the process of replenishing hope. (shrink)

Holism and emergence are coherent notions. The paper points to the classes of emergent phenomena -- such as autocatalysis -- that are taken as commonplace phenomena in biological sciences. Thus it questions the Democritean credo, “wholes are completely determined by their parts” (in some of its forms, called mereological determinism), that has become a dogma of contemporary philosophy. A living thing requires the ability to initiate, mediate and terminate processes that produce products that make up the whole. Autocatalysis is one (...) such mechanism, and its action at the level of the whole produces effects on the parts such that the properties, manifested by the parts in the absence of the whole engaged in autocatalysis, are altered. For these reasons, some writers suggest that autocatalysis is a law of organization and that it is emergent. It also appears that this is a case of downward causation -- one that clearly occurs in nature. If this is not a case of downward causation on Kim’s terms, then biological systems that are claimed to be emergent do not need to involve downward causation in his sense. The author thinks that this constitutes downward causation in an important sense -- the causal properties of the whole drive the behavior of the parts. Another set of examples comes from chaos dynamics. Relying on this evidence, the author challenges the Democritean credo (and mereological determinism) and shifts the onus of proof. (shrink)

BackgroundCoaching is increasingly viewed as a dyadic exchange of verbal and non-verbal interactions driving clients' progress. Yet, little is known about how the trajectory of dyadic interactions plays out in workplace coaching.MethodThis paper provides a multiple-step exploratory investigation of movement synchrony of dyads in workplace coaching. We analyzed a publicly available dataset of 173 video-taped dyads. Specifically, we averaged MS per session/dyad to explore the temporal patterns of MS across the cluster of dyads that completed 10 sessions, and a set (...) of 173 dyadic interactions with a varied number of sessions. Additionally, we linked that pattern to several demographic predictors. The results indicate a differential downward trend of MS.ResultsDemographic factors do not predict best fitting MS curve types, and only client age and coach experience show a small but significant correlation.DiscussionWe provide contextualized interpretations of these findings and propose conceptual considerations and recommendations for future coaching process research and practice. (shrink)

Advancing the reductionist conviction that biology must be in agreement with the assumptions of reductive physicalism (the upward hierarchy of causal powers, the upward fixing of facts concerning biological levels) A. Rosenberg argues that downward causation is ontologically incoherent and that it comes into play only when we are ignorant of the details of biological phenomena. Moreover, in his view, a careful look at relevant details of biological explanations will reveal the basic molecular level that characterizes biological systems, defined (...) by wholly physical properties, e.g., geometrical structures of molecular aggregates (cells). In response, we argue that contrary to his expectations one cannot infer reductionist assumptions even from detailed biological explanations that invoke the molecular level, as interlevel causal reciprocity is essential to these explanations. Recent very detailed explanations that concern the structure and function of chromatin—the intricacies of supposedly basic molecular level—demonstrate this. They show that what seem to be basic physical parameters extend into a more general biological context, thus rendering elusive the concepts of the basic level and causal hierarchy postulated by the reductionists. In fact, relevant phenomena are defined across levels by entangled, extended parameters. Nor can the biological context be explained away by basic physical parameters defining molecular level shaped by evolution as a physical process. Reductionists claim otherwise only because they overlook the evolutionary significance of initial conditions best defined in terms of extended biological parameters. Perhaps the reductionist assumptions (as well as assumptions that postulate any particular levels as causally fundamental) cannot be inferred from biological explanations because biology aims at manipulating organisms rather than producing explanations that meet the coherence requirements of general ontological models. Or possibly the assumptions of an ontology not based on the concept of causal powers stratified across levels can be inferred from biological explanations. The incoherence of downward causation is inevitable, given reductionist assumptions, but an ontological alternative might avoid this. We outline desiderata for the treatment of levels and properties that realize interlevel causation in such an ontology. (shrink)

When attempting to predict future events, people commonly rely on historical data. One psychological characteristic of judgmental forecasting of time series, established by research, is that when people make forecasts from series, they tend to underestimate future values for upward trends and overestimate them for downward ones, so-called trend-damping. Events in a time series can be experienced sequentially, or they can also be retrospectively viewed simultaneously, not experienced individually in real time. In one experiment, we studied the influence of (...) presentation mode on two sorts of judgment: predictions of the next event and estimation of the average value of all the events in the presented series. Participants' responses in dynamic mode were anchored on more recent events than in static mode for all types of judgment but with different consequences; hence, dynamic presentation improved prediction accuracy, but not estimation. These results are not anticipated by existing theoretical accounts; we develop and present an agent-based model—the adaptive anchoring model —to account for the difference between processing sequences of dynamically and statically presented stimuli. ADAM captures how variation in presentation mode produces variation in responses in both forecasting and judgment tasks. ADAM's model predictions for the forecasting and judgment tasks fit better with the response data than a linear-regression time series model. Moreover, ADAM outperformed autoregressive-integrated-moving-average and exponential-smoothing models, while neither of these models accounts for people's responses on the average estimation task. (shrink)

Noam Chomsky and Frances Egan argue that David Marr’s computational theory of vision is not intentional, claiming that the formal scientific theory does not include description of visual content. They also argue that the theory is internalist in the sense of not describing things physically external to the perceiver. They argue that these claims hold for computational theories of vision in general. Beyond theories of vision, they argue that representational content does not figure as a topic within formal computational theories (...) in cognitive science. I demonstrate that Chomsky’s and Egan’s claims about Marr’s theory are false. Marr’s computational theory contains a mathematical theory of visual content, based on empirical psychophysical evidence. It also contains mathematical descriptions of distal physical surfaces and objects, and of their optic projection to the perceiver. Much computational research on vision contains these types of intentional and externalist components within the formal, mathematical, theories. Chomsky’s and Egan’s claims demonstrate inadequate study and understanding of Marr’s work and other research in this area. Computational theories of vision, by containing empirically based mathematical theories of visual content, to this extent present naturalizations of semantics. (shrink)

This edition includes a new introduction by Peter J. Gomes that reflects on the impact of this book in the years since it was written.

We are witnessing increasing use of the Internet, particular social media, to criticize (perceived or actual) moral failings and misdemeanors. This phenomenon of so-called ‘online public shaming’ could provide a powerful tool for reinforcing valuable social norms. But it also threatens unwarranted and severe punishments meted out by online mobs. This paper analyses the dangers associated with the informal enforcement of norms, drawing on Locke, but also highlights its promise, drawing on recent discussions of social norms. We then consider two (...) crucial conditions that online public shaming must meet in order to be justifiable: proportionality and accountability. We argue that these requirements are in fact frequently violated, rendering most cases of online public shaming unjustified. While the use of online public shaming against others’ vices has some apparent virtues, it is currently rarely justified, given its own vices. (shrink)

In this book, Russell examines Hume's notion of free will and moral responsibility. It is widely held that Hume presents us with a classic statement of a compatibilist position--that freedom and responsibility can be reconciled with causation and, indeed, actually require it. Russell argues that this is a distortion of Hume's view, because it overlooks the crucial role of moral sentiment in Hume's picture of human nature. Hume was concerned to describe the regular mechanisms which generate moral sentiments such as (...) responsibility, and Russell argues that his conception of free will must be interprted within this naturalistic framework. He goes on to discuss Hume's views about the nature and character of moral sentiment; the extent to which we have control over our moral character; and the justification of punishment. Throughout, Russell argues that the naturalistic avenue of interpretation of Hume's thought, far from draining it of its contemporary interest and significance, reveals it to be of great relevance to the ongoing contemporary debate - particuarly in relation to the views of P.F. Strawson and his influential paper "Freedom and Resentment". (shrink)

Reasons and reasoning were central to the work of Paul Grice, one of the most influential and admired philosophers of the late twentieth century. In the John Locke Lectures that Grice delivered in Oxford at the end of the 1970s, he set out his fundamental thoughts about these topics; Aspects of Reason is the long-awaited publication of those lectures. This immensely rich work, powerfully evocative of the mind of its author, will refresh and illuminate discussions in many areas of (...) contemporary philosophy. (shrink)

"Evidence of a flight from reason is as old as human record-keeping: the fact of it certainly goes back an even longer way. Flight from science specifically, among the forms of rational inquiry, goes back as far as science itself... But rejection of reason is now a pattern to be found in most branches of scholarship and in all the learned professions."--from the introduction In the widely acclaimed Higher Superstition: The Academic Left and Its Quarrels with Science, Paul R. (...) Gross and Norman Levitt offered a spirited response to the "science bashers," raising serious questions about the growing criticism of scientific practice from humanists and social scientists on the academic left. Now, in The Flight from Science and Reason, Gross and Levitt are joined by Martin W. Lewis to bring together a diverse and distinguished group of scholars, scientists, and experts to engage these questions from a wide variety of perspectives. The authors take on critics of science whose views range from moderate to extreme, from social constructivists to deconstructionists, from creationists and feminists to Afro-centrists. They discuss the rise of "alternative medicine" and radical environmentalism (here skewered as "ecosentimentalism"). They explain why the "uncertainty principle" does not work as a metaphor for ambiguity, and why "chaos theory" cannot be invoked without an understanding of mathematics. Throughout, they grapple with the paradox inherent in arguing with opponents who contend that reason itself, and thus logic, is suspect. Distributed for the New York Academy of Sciences. (shrink)

In this chapter a new problem about rule-following is outlined, one that is distinct both from Kripke’s and Wright’s versions of the problem. This new problem cannot be correctly responsed to, as Kripke’s can, by invoking Wright’s Intentional Account of rule-following. The upshot might be called, following Kant, an antinomy of pure reason: we both must — and cannot — make sense of someone’s following a rule. The chapter explores various ways out of this antinomy without here endorsing any of (...) them. (shrink)

This is a collection in translation of essays by Paul Ricoeur which presents a comprehensive view of his philosophical hermeneutics, its relation to the views of his predecessors in the tradition and its consequences for the social sciences. The volume has three parts. The studies in the first part examine the history of hermeneutics, its central themes and the outstanding issues it has to confront. In Part II, Ricoeur's own current, constructive position is developed. A concept of the text (...) is formulated as the implications of the theory are pursued into the domains of sociology, psychoanalysis and history. Many of the essays appear here in English for the first time; the editor's introduction brings out their background in Ricoeur's thought and the continuity of his concerns. The volume will be of great importance for those interested in hermeneutics and Ricoeur's contribution to it, and will demonstrate how much his approach offers to a number of disciplines. (shrink)

Paul Thom's book presents Kilwardby's science of logic as a body of demonstrative knowledge about inferences and their validity, about the semantics of non-modal and modal propositions, and about the logic of genus and species. This science is thoroughly intensional. It grounds the logic of inference on "that in virtue of which" the inference holds. It bases the truth conditions of propositions on relations between conceptual entities. It explains the logic of genus and species through the notion of essence. (...) Thom interprets this science as a formal logic of intensions with its own proof theory and semantics. This comprehensive reconstruction of Kilwardby's logic shows the medieval master to be one of the most interesting logicians of the thirteenth century. (shrink)

The ethical issues raised by cybersecurity practices and technologies are of critical importance. However, there is disagreement about what is the best ethical framework for understanding those issues. In this paper we seek to address this shortcoming through the introduction of a principlist ethical framework for cybersecurity that builds on existing work in adjacent fields of applied ethics, bioethics, and AI ethics. By redeploying the AI4People framework, we develop a domain-relevant specification of five ethical principles in cybersecurity: beneficence, non-maleficence, autonomy, (...) justice, and explicability. We then illustrate the advantages of this principlist framework by examining the ethical issues raised by four common cybersecurity contexts: penetration testing, distributed denial of service attacks (DDoS), ransomware, and system administration. These case analyses demonstrate the utility of this principlist framework as a basis for understanding cybersecurity ethics and for cultivating the ethical expertise and ethical sensitivity of cybersecurity professionals and other stakeholders. (shrink)

De milieuproblematiek staat pas sinds kort op de agenda als een fenomeen dat de mensheid bedreigt. Toch blijkt het negentiende-eeuwse gedachtegoed van Karl Marx verrassende inzichten te bieden om deze actuele problemen te duiden. Marx laat zien dat het menselijk ingrijpen in de natuur leidt tot zelfvervreemding: de mens ondermijnt zijn bestaan als een wezen dat zelf deel uitmaakt van de natuur. Deze zelfvervreemding cumuleert in de kapitalistische samenleving. Marx lezend zien we dat de milieuproblematiek geen historische vergissing is, maar (...) fundamenteel samenhangt met de mens als redelijk wezen. Onze beheersingsrede heeft geleid tot de vervreemding van de natuur. Toch geeft dezelfde rede die de mens de vrijheid biedt zich boven het ecologische evenwicht te verheffen, hem de mogelijkheid zich te verzoenen met de natuur. Marx verwijst naar dit dubbele gezicht van de rede als hij stelt dat het 'rijk van de vrijheid' in de schoot van het kapitalisme wordt geboren. In dit boek onderzoekt Paul Cobben welke aanzetten de huidige samenleving biedt om vorm te geven aan de verzoening met de natuur. Paul Cobben is emeritus hoogleraar geschiedenis van de moderne filosofie aan Tilburg University. Momenteel is hij gastonderzoeker aan de Vrije Universiteit Amsterdam en redacteur van de serie 'Critical Studies in German Idealism'. Van zijn hand verscheen o.a. 'Value in Capitalist Society. Rethinking Marx's Criticism of Capitalism' (2015)."-- Publisher information. (shrink)

Foreword William Schweiker Paul Tillich, one of the great Protestant theologians of the twentieth century, addresses in Morality and Beyond a basic problem ...

Logic has acquired a reputation for difficulty, perhaps because many of the approaches adopted have been more suitable for mathematicians than computer scientists. This book shows that the subject is not inherently difficult and that the connections between logic and declarative language are straightforward. Many exercises have been included in the hope that these will lead to a much greater confidence in manual proofs, therefore leading to a greater confidence in automated proofs.

Logic has acquired a reputation for difficulty, perhaps because many of the approaches adopted have been more suitable for mathematicians than computer scientists. This book shows that the subject is not inherently difficult and that the connections between logic and declarative language are straightforward. Many exercises have been included in the hope that these will lead to a much greater confidence in manual proofs, therefore leading to a greater confidence in automated proofs.

The proteins encoded by the ras proto‐oncogenes play critical roles in normal cellular growth, differentiation and development in addition to their potential for malignant transformation. Several proteins that are involved in the control of the activity of p21ras have now been characterised. p120GAP stimulates the GTPase activity of p21ras and hence acts as a negative regulator of ras proteins. It may be controlled by tyrosine phosphorylation or association with tyrosine phosphorylated proteins. The neurofibromatosis type 1 (NF 1) gene also encodes (...) a potential GTPase activating protein which is likely to be subject to a different control mechanism. Guanosine nucleotide exchange factors for p21ras have now been identified: these may be positive regulators of ras protein function. It appears that p21ras is subject to rapid regulation by several distinct mechanisms which are likely to vary in different cell types; the ras proteins are thereby able to act as very sensitive cellular monitors of the extracellular environment. (shrink)

Schoenflies point groups are presented in terms of spatial partitions and Laue classes based on abstract groups. A much simpler system using only a minimal set of generators for three dimensional groups is then presented in the same form. This simplified treatment allows group operations of a given Laue class to be correlated to a greatly simplified Mulliken-style notation for irreducible representations of that class. Transformation matrix representations of point groups in the simplified style can then be manipulated according to (...) their position in the class or to their sub-groups in very clear procedures. Simple rules can replace the large numbers of tables necessary in the Schoenflies approach. Some applications of the method are described. (shrink)

In this study of space and power and knowledge in France from the 1830s through the 1930s, Rabinow uses the tools of anthropology, philosophy, and cultural criticism to examine how social environment was perceived and described. Ranging from epidemiology to the layout of colonial cities, he shows how modernity was revealed in urban planning, architecture, health and welfare administration, and social legislation.

The Renaissance was a period of great intellectual change and innovation as philosophers rediscovered the philosophy of classical antiquity and passed it on to the modern age. Renaissance philosophy is distinct both from the medieval scholasticism, based on revelation and authority, and from philosophers of the seventeenth and eighteenth centuries who transformed it into new philosophical systems. Despite the importance of the Renaissance to the development of philosophy over time, it has remained largely understudied by historians of philosophy and professional (...) philosophers. This anthology aims to correct this by providing scholars and students of philosophy with representative translations of the most important philosophers of the Renaissance. Its purpose is to help readers appreciate philosophy in the Renaissance and its importance in the history of philosophy. The anthology includes translations from philosophers from the thirteenth to the seventeenth centuries, and it ranges from works on moral and political philosophy, to metaphysics, epistemology, and natural philosophy, thereby providing historians and students of philosophy with a sense for the nature, breadth, and complexity of philosophy in the Renaissance. Each translation is accompanied by an introduction by a historian of Renaissance philosophy, as well as select secondary sources, in order to encourage further study. (shrink)

Paul Helm investigates what religious faith is and what makes it reasonable.

Logic brings elementary logic out of the academic darkness into the light of day. Paul Tomassi makes logic fully accessible for anyone trying to come to grips with the complexities of this challenging subject. This book is written in a patient and user-friendly way which makes both the nature and value of formal logic crystal clear. This textbook proceeds from a frank, informal introduction to fundamental logical notions to a system of formal logic rooted in the best of our (...) natural deductive reasoning in daily life. The book includes plenty of exercise to put the students' reading to test, summay boxes of key points, a glossary and many illustrations. This book will be useful to any student who needs a patient and comprehensible introduction to what otherwise can be a daunting subject. (shrink)

We sometimes strive to achieve difficult goals when our evidence suggests that success is unlikely – not just because it will require strength of will, but because we are targets of prejudice and discrimination or because success will require unusual ability. Optimism about one’s prospects can be useful for persevering in these cases. That said, excessive optimism can be dangerous; when our evidence is unfavourable, we should be at most agnostic about whether we will succeed. This paper explores the nature (...) and rational significance of agnostic practical commitments. Most importantly, the rationality of striving against the odds can depend on investing in a plan for failure: a plan B. I aim to make headway on an account of what backup plans are, how they are related to primary plans, and whether the standard norms of plan rationality apply to our agnostic commitments. (shrink)

The hatchet and the seed -- A tree with deep roots -- The critical tools -- A field crystallizes -- Destruction of nature -- Construction of nature -- Degradation and marginalization -- Conservation and control -- Environmental conflict -- Environmental identity and social movement -- Where to now?