ABSTRACT:‘Race’ has long searched for a stable, suitable idea, with no consensus on a master meaning in sight. What I call deflationary pluralism about the existence of race recognizes that various meanings may be true as far as they go but avoids murky disputes over whether there are races in some sense. Once we have rejected the notion that racial essences yield innate cognitive differences, there is little point to arguing over the race idea. In its place, I propose the (...) idea of socioancestry, which jettisons racial thinking yet recognizes the social dynamics of color. For example, Black Americans, many of whom have traceable non-African ancestry, constitute an Africa-identified, socioancestrally black subgroup. ‘Race’ talk is not needed to sustain legitimate color-conscious approaches to social identity and social justice. Long-standing fixation on the race idea has obscured the simple truth that visible continental ancestry is the root of the social reality of color consciousness. (shrink)

Innocence is a notion that can prove controversial. Claims of innocence typically support not imposing burdens on the innocent when their conduct is relevantly unobjectionable. This paper examines innocence in the context of violent conflict between states or groups. Many thinkers about the morality of such violence want to establish a principle that would protect innocent civilians. Yet the common view in just war theory does not affirm the moral innocence of civilians. Similarly, the common view that soldiers have an (...) equal right to kill does not affirm their equal moral culpability. (shrink)

Common sense supports the idea that we can have morally significantreasons for giving priority to the interests of persons for whom wehave special concern. Yet there is a real question about the natureof such reasons. Many people seem to believe that there are biologicalor metaphysical special relations, such as family, race, religion orpersonal identity, which are in themselves morally important and thussupply reasons for special concern. I maintain that there are nogrounds for accepting this. What matters morally, I argue, is (...) thesubstance of personal or wider social relationships. My ``substantivist''account of the source of morally salient reasons for special concernis positioned between nonreductionist and strong voluntarist views ofspecial responsibilities. Substantivism is more plausible than theseviews and has important implications for how we approach morallyweighing personal versus impartial reasons. (shrink)

The use of excessive force in war is an all-too-familiar phenomenon that resists an obvious philosophical solution. A principle that prohibits disproportionate use of force is commonly recognized. Yet I argue that an adequate proportionality principle is more difficult to formulate than may appear. There are too many morally relevant considerations to be weighed — especially harms to combatants versus noncombatants, depending on which side they are on — and we have no clear idea how to weigh them. These difficulties (...) are avoided through the dominant understanding of proportionality codified in international law and military practice, which rules out only attacks that intentionally target civilians or that involve negligence in targeting or conduct. We should find it harder to deny that use of force can be excessive despite conforming to these narrow constraints. Specifically, we can clearly identify as excessive the use of force in pursuit of unjust goals. This will still leave a range of hard cases in which there is a just cause for war. For these cases, I propose a "golden rule" test of the sincerity of deliberation about whether a use of force would be excessive. Relying on narrow constraints that would govern use of force in war can be morally worse than not having them. The golden rule test can help to direct us toward broader, reasonable moral considerations regarding excessive force. (shrink)

What is the relation between the rules of war covered by ‘the war convention’ and the source of their normative authority? According to Michael Walzer, these rules have normative authority by virtue of being widely established in theory and practice and conforming to our moral sensibilities. It is striking that his influential account of just war has a conventionalist grounding similar to his more scrutinized general theory of justice. Indeed, we should question whether a shared moral understanding is an adequate (...) basis for morally obligating parties who might challenge the rules under the war convention. I argue that rules of war need the support of moral judgments whose normative authority is ultimately not conventional in nature. Reasonable objections to the war convention exert pressure to revise its standard principles or to admit that these principles lack general moral force. Such objections, inchoate though they may be in international political discourse, seem a source of commonly voiced skepticism of morality in international relations. Debate about the merits of alternative principles of just war has the advantage of engaging with this skepticism. This opens up the possibility that less powerful or more conscientious parties could play a constructive role in a public and more democratic discourse of just war. Key Words: Karl von Clausewitz • convention • Gilbert Harman • just war theory • morality • normative authority • political realism • war • the war convention • Michael Walzer. (shrink)

The standard, non‐repeated prisoner's dilemma poses no true dilemma about rationality, we argue. What the prisoners ought rationally to do, unless they are selfless, depends on the relationship of trust that they have or lack with one another. This helps to diffuse the apparent conflict between individual and collective rationality. If the prisoners have reason to trust one another, pursuing a joint strategy would be rational for them. In the absence of trust, pursuing an individual strategy would be rational. The (...) solution that is supposed to be puzzling – because each prisoner confessing is worse for both than the alternative on which both remain silent – is simply the rational solution for persons who have no reason to trust one another. Philosophers have been misled by the apparent availability of the better alternative. Collective rationality is not relevant for persons who do not stand in a trusting relationship. When they do, there is no unresolved conflict between their individual and collective points of view.1. (shrink)

Knowledge about aspects that influence recovery and adaptation in the postacute phase of disabling health events is key to understanding how best to provide appropriate rehabilitation and health services. Qualitative longitudinal research makes it possible to look for patterns, key time points and critical moments that could be vital for interventions and supports. However, strategies that support robust data management and analysis for longitudinal qualitative research in health‐care are not well documented in the literature. This article reviews three challenges encountered (...) in a large longitudinal qualitative descriptive study about experiences of recovery and adaptation after traumatic brain injury in New Zealand, and the strategies and technologies used to address them. These were (i) tracking coding and analysis decisions during an extended analysis period; (ii) navigating interpretations over time and in response to new data; and (iii) exploiting data volume and complexity. Concept mapping during coding review, a considered combination of information technologies, employing both cross‐sectional and narrative analysis, and an expectation that subanalyses would be required for key topics helped us manage the study in a way that facilitated useful and novel insights. These strategies could be applied in other qualitative longitudinal studies in healthcare inquiry to optimise data analysis and stimulate important insights. (shrink)

(No abstract is available for this citation).

Recent ideological positioning on the world stage has born a startling resemblance to a form of positioning within nursing theory – that of taking complex ideas, reducing them to a simplistic binary form, and uncritically adopting one half of that form. In some cases, this adoption of a binary position has led to a passionately held form of ‘othering’ that prohibits a healthy and critical engagement with ideas. As alluring as settling for the binary form may be – we argue (...) for holding binaries in tension as a catalyst for stimulating dialogue – reasoning and exploration of new ways of wrestling with the social and moral complexity of nursing. (shrink)

Alzheimer's disease is characterized by plaques of amyloid-beta peptide, cleaved from amyloid-beta protein precursor . Our hypothesis is that lifespan profiles of AD-associated mRNA and protein levels in monkeys would differ from mice and that differential lifespan expression profiles would be useful to understand human AD pathogenesis. We compared profiles of AbetaPP mRNA, AbetaPP protein, and Abeta levels in rodents and primates. We also tracked a transcriptional regulator of the AbetaPP gene, specificity protein 1 , and the beta amyloid precursor (...) cleaving enzyme . In mice, AbetaPP and SP1 mRNA and their protein products were elevated late in life; Abeta levels declined in old age. In monkeys, SP1, AbetaPP, and BACE1 mRNA declined in old age, while protein products and Abeta levels rose. Proteolytic processing in both species did not match production of Abeta. In primates, AbetaPP and SP1 mRNA levels coordinate, but an inverse relationship exists with corresponding protein products as well as Abeta levels. Comparison of human DNA and mRNA sequences to monkey and mouse counterparts revealed structural features that may explain differences in transcriptional and translational processing. These findings are important for selecting appropriate models for AD and other age-related diseases. (shrink)

The sporadic nature of Alzheimer's disease argues for an environmental link that may drive AD pathogenesis; however, the triggering factors and the period of their action are unknown. Recent studies in rodents have shown that exposure to lead during brain development predetermined the expression and regulation of the amyloid precursor protein and its amyloidogenic beta-amyloid product in old age. Here, we report that the expression of AD-related genes [APP, BACE1 ] as well as their transcriptional regulator were elevated in aged (...) monkeys exposed to Pb as infants. Furthermore, developmental exposure to Pb altered the levels, characteristics, and intracellular distribution of Abeta staining and amyloid plaques in the frontal association cortex. These latent effects were accompanied by a decrease in DNA methyltransferase activity and higher levels of oxidative damage to DNA, indicating that epigenetic imprinting in early life influenced the expression of AD-related genes and promoted DNA damage and pathogenesis. These data suggest that AD pathogenesis is influenced by early life exposures and argue for both an environmental trigger and a developmental origin of AD. (shrink)

Two general features of metameric patterning in Drosophilaare considered: (1) maintenance of a constant number of metameres (segments or parasegments) in the face of variation in length of the embryo; (2) expression of pattern by on‐off switchings of particular genes, with only three or four rows of cells to each element of pattern. For each of these features, the general strategic question is raised: could reaction‐diffusion theory account for this? In both cases, it is answered affirmatively. For the second feature, (...) this review contains some hitherto unpublished computer simulations by one of us (K. Y. T.), illustrating that a reaction‐diffusion mechanism can be transformed into a patterned switching mechanism by nothing more than compartmenting of the diffusion region. For the scale of three compartments to one pattern repeat unit (representing three rows of cells to a segment) the switching pattern predicted by computation is two‐off to one‐on. This resembles the pattern of expression of the engrailed gene, posteriorly localized in each segment. (shrink)

This collection of essays by leading patristic scholars of the U.K. and Germany illuminates aspects of the relation between Christian faith and Greek philosophy.

John Rawls’ method of reflective equilibrium is the most influential methodology in contemporary ethics.This paper argues that this influence is undeserved, for two reasons. First, reflective equilibrium fails to accomplish two tasks that give us reason to care about methodology. On the one hand, it fails to explain how (or whether) moral knowledge is possible.This is because the method is explicitly oriented towards the distinct (and less interesting) task of characterizing our moral sensibilities. On the other hand, the method fails (...) to provide an informative way of adjudicating central methodological debates in ethics. Second, where Rawls’ method –and the background methodology he uses to motivate it –do have substance, that substance is implausible. The role of dispositions in the method entails that it endorses obviously irrational inferences. Further, the method makes substantively implausible distinctions between the dispositions that are allowed to play a methodological role. Rawls' background methodology appeals to the idea of a psychology in ‘wide reflective equilibrium’. However, both formal and empirical path-dependence considerations strongly suggest that there is nothing even minimally determinate that is someone’s psychology in ‘wide reflective equilibrium’. I close by exploring salient attempts to salvage the spirit of reflective equilibrium by abandoning elements of Rawls’ approach. I argue that none of these attempts succeed. I conclude that appeal to the method of reflective equilibrium is not a helpful means of addressing pressing methodological questions in ethics. In a slogan, reflective equilibrium is methodologically irrelevant. (shrink)

This paper argues for what I call modest ethical veganism: the view that it is typically wrong to use or eat products made from or by animals such as cows, pigs, or chickens. The argument has three central parts. First, I argue that a central explanation for the wrongness of causing suffering rests upon what it is like to experience such suffering, and that we have good reasons to think that animals suffer in ways that are relevantly analogous to humans. (...) Second, I argue that animals can have better and worse lives, and that a central explanation for the wrongness of killing is that it deprives the victim of the valuable life that they would otherwise have had. Third, I argue that it is wrong to cooperate with massive wrongdoing. By consuming animal products, we typically support institutions that engage in massive and systematic wrongful treatment of animals. We thus ought to become vegan. (shrink)

This article argues that the best way to pursue systematic normative ethical theorizing involves metaethical enquiry. My argument builds upon two central claims. First, I argue that plausible metaethical accounts can have implications that can help to resolve the methodological controversies facing normative ethics. Second, I argue that metaethical research is at least roughly as well supported as normative ethical research. I conclude by examining the implications of my thesis. Inter alia, it shows that the common practice of engaging in (...) systematic normative theorizing uninformed by metaethical commitments offers a significant and troubling hostage to metaethical fortune. (shrink)

This essay explores Bernard Williams’s portrayal of his, Alasdair MacIntyre’s, and Charles Taylor’s views on how to move in relationship to religion in our modern world: backward in it (MacIntyre), forward in it (Taylor), and out of it (Williams). I contend that this portrayal is not entirely accurate in each case, though there is some truth in it, and that looking at each author’s view on the relationship of religion to modernity is instructive for those of us who wish to (...) keep religious faith alive in our modern, secular age. I begin with Williams, and then discuss MacIntyre and Taylor in turn. I seek to show how MacIntyre and Taylor can help us to overcome the challenge to religious faith that Williams presents and how both offer important guidance for the life of faith in our modern, secular age. (shrink)

Two currently much discussed views about truth, truth pluralism and truth relativism, are found in Sellars’s writings. I show that his motivations for adoping these views are interestingly different from those shared by most of their recent advocates. First, I explain how Sellars comes to embrace a version of truth pluralism. I argue that his version overcomes a difficulty confronting pluralists, albeit at a serious cost. Then I argue that Sellars’s truth pluralism isn’t motivated by his interest in domains of (...) discourse beyond the “matter-of-factual.” Rather, the key to his truth pluralism, his analysis of truth as “semantical assertibility,” is motivated by the same consideration that leads him to adopt truth relativism. This is his interest in applying semantic notions to discourse that embodies conceptual structures other than ours. Despite their common motivation, I conclude that Sellars’s relativism is independent of, and indeed stands in tension with, the analysis of truth that underlies his pluralism. (shrink)

Surveys Western literature and thought to reveal the evolution of the ideals of sincerity and authenticity.

This chapter explores two central questions in the conceptual ethics of normative inquiry. The first is whether to orient one’s normative inquiry around folk normative concepts (like KNOWLEDGE or IMMORAL) or around theoretical normative concepts (like ADEQUATE EPISTEMIC JUSTIFICATION or PRO TANTO PRACTICAL REASON). The second is whether to orient one’s normative inquiry around concepts whose normative authority is especially accessible to us (such as OUGHT ALL THINGS CONSIDERED), or around concepts whose extension is especially accessible to us (such as (...) BETRAYAL). The chapter aims to make vivid and plausible a range of possible answers to these questions, and important forms of argument that can be used to favor certain answers over others. (shrink)

Based on specific documentary evidence, historian Lionel Jensen reveals how 16th- and 17th-century Western missionaries used translations of the ancient RU ...

El método de la “libre investigación científica del derecho” propuesto por François Gény ha marcado toda una generación de juristas. Tratado con detenimiento a lo largo de su extensa y compleja obra, la libre investigación científica se presenta como un método completo destinado a orientar al jurista en la creación, interpretación y aplicación del derecho positivo. Por desventura, el clima ambiente en el que nació su obra y en el que tuvo que desenvolverse con posterioridad, dominado por la escuela de (...) la exégesis, no ha sabido extraer de la obra de Gény más que elementos dispares no haciendo justicia a su método. En la actualidad, el redescubrimiento de su método de la libre investigación científica permitirá combatir el anquilosamiento dogmático, evitar los excesos formalistas, y aportar elementos de interés para la investigación iusfilosófica de nuestro tiempo. El método de la “libre investigación científica del derecho” propuesto por François Gény ha marcado toda una generación de juristas. Tratado con detenimiento a lo largo de su extensa y compleja obra, la libre investigación científica se presenta como un método completo destinado a orientar al jurista en la creación, interpretación y aplicación del derecho positivo. Por desventura, el clima ambiente en el que nació su obra y en el que tuvo que desenvolverse con posterioridad, dominado por la escuela de la exégesis, no ha sabido extraer de la obra de Gény más que elementos dispares no haciendo justicia a su método. En la actualidad, el redescubrimiento de su método de la libre investigación científica permitirá combatir el anquilosamiento dogmático, evitar los excesos formalistas, y aportar elementos de interés para la investigación iusfilosófica de nuestro tiempo. (shrink)

The past few decades have witnessed an extraordinary revival of interest in metanormative non-naturalism. Despite this interest, it is still unclear how to understand the distinctive metaphysical commitments of this view. We illustrate the relevant difficulties by examining what is arguably the most prominent class of contemporary attempts to formulate non-naturalism’s metaphysical commitments. This class of proposals, exemplified in work by Gideon Rosen and Stephanie Leary, characterizes the distinctive metaphysical commitments of non-naturalism in terms of metaphysical grounding and essence. We (...) argue that these proposals overgeneralize: they either misclassify intuitively naturalistic hypotheses about the metaphysics of normativity as “non-naturalist”, or misclassify hypotheses in other areas of metaphysics. We argue that this problem stems from features of grounding itself. We suggest a more promising alternative for formulating non-naturalism, which revolves around the notion of objective similarity between classes of properties. We conclude by drawing some general lessons for inquiry about the metaphysics of normativity, and about metaphysics in general. (shrink)

The conceptual ethics of normativity involves normative reflection on normative thought and talk. One motive for engaging in this project is to seek to either vindicate or improve one’s existing normative concepts. This paper clarifies and addresses a deep challenge to the conceptual ethics of normativity, when it is motivated in this way. The challenge arises from the fact that we need to use some of our own normative concepts in order to evaluate our normative concepts. This might seem objectionably (...) circular, akin to trying to verify the accuracy of a ruler by checking it against itself. We dub this the vindicatory circularity challenge. If the challenge cannot be met, it would suggest that all normative inquiry (not just the conceptual ethics of normativity) rests on worryingly arbitrary foundations. We defend a way of answering the challenge that adapts anti-skeptical resources from epistemology. Along the way, we reject several alternative replies to the challenge. These include dismissing the challenge because it cannot be formulated with our concepts, answering it by appeal to a distinctive normative concept, and answers that appeal to certain metaphysical or metasemantic resources. (shrink)

One important activity in conceptual ethics and conceptual engineering involves proposing to associate a new semantics with an existing word. Many philosophers think that one important way to evaluate such a proposal concerns whether it preserves the “topic” picked out by the existing word, and several have offered competing proposals concerning what is required to preserve topic. Our paper is focused on the conceptual ethics question of how conceptual engineers should use the term ‘topic continuity’. We provide and defend a (...) context- sensitive answer to this question. Our answer is motivated by the idea that there are several distinct considerations that we can reasonably care about (and which many conceptual engineers already do care about) in thinking about “topic continuity”, and, moreover, that how best to weigh them against each other can vary from context to context. On our proposal, ‘topic continuity’ can function as a useful representational device that enables coordination by inquirers with respect to these concerns. We conclude by locating our account in a broader way of thinking about topic continuity across a range of inquiries. (shrink)

Current empirical evidence does not seem to confirm that an improvement in living conditions is the cause of the shift in the human mindset toward innovation and long-term risky investment. However, it may well be one of the conditions for greater tolerance of income inequality in exchange for a steady increase in average income.

Laborie and Hessayon bring rare prophetic and millenarian texts to an international audience by presenting sources from all over Europe (broadly defined), and across the early modern period in English for the first time.

This paper advertises the importance of distinguishing three different foundational projects about epistemic thought and talk, which we call “systematic normative epistemology”, “metaepistemology”, and “the conceptual ethics of epistemology”. We argue that these projects can be distinguished by their contrasting constitutive success conditions. This paper is motivated by the idea that the distinctions between these three projects matter for epistemological theorizing in ways that have been underappreciated in philosophical discussion. We claim that attention to the threefold distinction we advance allows (...) us to better understand and evaluate existing views and debates in the field; identify and appreciate new or underexplored theoretical options in the field; and avoid important defects and ambiguities in our research on epistemic topics. (shrink)