The genes involved in methionine biosynthesis are scattered throughout the Escherichia coli chromosome and are controlled in a similar but not coordinated manner. The product of the metJ gene and S‐adenosylmethionine are involved in the repression of this ‘regulon’.

Examines the findings of scientific research into the thought processes of animals and argues that animals are capable of conscious thought.

Winner of the Los Angeles Times Book Prize With a new preface by the author In his most powerful and important book, renowned psychiatrist Robert Jay Lifton presents a brilliant analysis of the crucial role that German doctors played in the Nazi genocide. Now updated with a new preface, The Nazi Doctors remains the definitive work on the Nazi medical atrocities, a chilling exposé of the banality of evil at its epitome, and a sobering reminder of the darkest side (...) of human nature. (shrink)

This paper offers an overview of "the species problem", arguing for a view of species as homeostatic property cluster kinds, positioning the resulting form of realism about species as an alternative to the claim that species are individuals and pluralistic views of species. It draws on taxonomic practice in the neurosciences, especially of neural crest cells and retinal ganglion cells, to motivate both the rejection of the species-as-individuals thesis and species pluralism.

Drawing on a passage from Ramsey's Truth and Probability, we formulate a simple, plausible constraint on evaluating the accuracy of credences: the Calibration Test. We show that any additive, continuous accuracy measure that passes the Calibration Test will be strictly proper. Strictly proper accuracy measures are known to support the touchstone results of accuracy-first epistemology, for example vindications of probabilism and conditionalization. We show that our use of Calibration is an improvement on previous such appeals by showing how it answers (...) or sidesteps problems that have been raised for previous work in this area. (shrink)

The thirty chapters work through various fundamental metaphysical issues, sometimes focusing more on scholastic thought, sometimes on the seventeenth century.

Are interpersonal comparisons of desire possible? Can we give an account of how facts about desires are grounded, that underpins such comparisons? This paper supposes the answer to the first question is yes, and provides an account of the nature of desire that explains how this is so. The account is a modification of the interpretationist metaphysics of representation that the author has recently been developing. The modification is to allow phenomenological affective valence into the “base facts” on which correct (...) interpretation is grounded. To use this extra resource within that theory to vindicate interpersonal comparisons, we will need to appeal rational connections between level of valence and level of desire, which this paper sets out and examines. (shrink)

In delineating a trajectory of human history, anthropology and other social sciences have tended to describe traditional life in particular geographic terms while leaving modem experience universal in scope. Studies of science and technology, while helping to locate and describe centers of modern practice, have less frequently explored their edges. Using a case study of the location of the primary French/european space launch site in French Guiana, this article examines technologies associated with the development of space beyond the atmosphere by (...) evaluating the impact of rockets and satellites on the construction of human space on the ground. Exploring the social significance of a modem sky and its transformation of one tropical margin into a technical center, the question of where things are becomes one of how they are defined. The modem appears less a placeless universal center and more a moving boundary, one dividing humans, nature, and technology into less stable domains. (shrink)

The paper offers an analysis of Protagoras’ fr. DK 80 B 1 and rejects the traditional reading of Protagoras as relativist. By considering the ipsissima verba that Protagoras makes use of in his passage, it is argued that alternative interpretations are possible, of which epistemological reism and psychological individualism are proposed. On a more general level, it is discussed to what extent Protagoras’ fragment contains descriptive rather than normative claim.

In lieu of an abstract, here is a brief excerpt of the content:Diacritics 31.3 (2001) 3-14 [Access article in PDF] IntroductionTheory, Globalization, Cultural Studies, and the Remains of the University Marc Redfield Theory, globalization, university: not just any words. So much commentary has grown up around them; and to write about one of these terms seems always to involve writing about another, sliding down a chain of associations that on the one hand leads straight to the most reductive American (...) mass-media representations of the academy (theory as a species of "postmodernism," ruining the university), yet on the other hand structures some of the most interesting and challenging writing in the humanities today. Cultural studies is perhaps a somewhat more recent and less layered term, but it too has come to serve as a charged nexus of discussion, and has proved inextricable from discussions of theory in the university in a globalized world. Yet despite the commerce among these keywords, the debates about them have tended, with notable exceptions, to remain somewhat distinct. Identifiable mini-traditions exist: arguments about theory that in some of their versions have persisted nearly unaltered since the early 1970s; more recent debates about cultural studies; a conflux of sociological, economic, and cultural discussions around the notion of globalization; an ongoing debate about the university, most recently galvanized by Bill Readings's University in Ruins (1996). 1 Our title offers a slant-rhyme homage to Readings's book, which most of our contributors reference and two or three engage directly, and which constitutes an exemplary effort to provide a story about the modern and postmodern university that would also be a story about globalization, theory, and cultural studies.It is the wager of this special issue of Diacritics that such stories demand to be told, because in fractured form they are persistently being told, through the relays that take us from one keyword or discursive microtradition to another. This does not mean that we expect to come up with a coherent metanarrative—to ascend, on the wings of speculation, to a vantage from which this particular quadrant of modernity's rugged landscape would become visible. In meditating on theory, globalization, cultural studies, and the university, we are directing our thinking toward internally split conceptual nodes that never quite resolve into stable concepts to be apprehended. Samuel Weber, always attuned [End Page 3] to the complexities of words, begins his contribution to this special issue by unpacking its title into a sequence of contradictions. Theory as conceptual vision (theoria) names the subject's appropriation of objects; yet in recent decades theory also has come to signify a critique of the subject-object model of cognition. The university is the institutional site of both sorts of theory: on the one hand, dedicated to the transmission and production of universally valid cognition; on the other hand, the place where a theoretical critique of theory has found its ambivalent and precarious, but to some extent effective, occasion. Globalization suggests on the one hand the crossing of frontiers and the transformation of substance into relation, yet on the other hand names the reinstatement of substance and identity at the level of the "globe" itself. Weber wrote his essay before I added cultural studies to the special issue's title, but one can easily extend his observation to this fourth term: on the one hand, cultural studies summarizes a range of approaches that have in common a valorization of the local and particular; on the other hand, in its all-embracing emptiness, the adjective cultural invokes the formalization of the human that constitutes the master narrative of aesthetic ideology. None of these terms yield a stable precipitate, and their interrelations are correspondingly volatile.The matter is further complicated by the deep roots and many-layered contexts of these institutionally and historically local arguments. In their instability and doubleness, both theory and cultural studies form part of the vast, border-rupturing discourse of modern aesthetics. Indeed, the case can be made—I have tried to make it elsewhere—that the journalistic equation of "theory" with "deconstruction" and the subsequent confusing of "theory" (as "deconstruction") with "cultural... (shrink)

In the good old days, when general philosophy of science ruled the Earth, a simple division was often invoked to talk about philosophical issues specific to particular kinds of science: that between the natural sciences and the social sciences. Over the last 20 years, philosophical studies shaped around this dichotomy have given way to those organized by more fine-grained categories, corresponding to specific disciplines, as the literatures on the philosophy of physics, biology, economics and psychology--to take the most prominent four (...) examples--have blossomed. In general terms, work in each of these areas has become increasingly enmeshed with that in the corresponding science itself, increasingly naturalistic (in at least one sense of that term), and in my view, increasingly interesting. (shrink)

If the world itself is metaphysically indeterminate in a specified respect, what follows? In this paper, we develop a theory of metaphysical indeterminacy answering this question.

My aim is to propose affectivity as a criterion for personal identity. My proposal is to be taken in its weak version: affectivity as _only one_ of the criteria for personal identity. I start by arguing for affectivity being a better candidate as a criterion for personal identity than thinking. Next, I focus on synchronic vs. diachronic and on ontic vs. epistemic distinctions (my proposal will concern diachronic ontic personal identity) and consider the realm of affectivity in its temporal dimension. (...) In my argument, I rely on the genuineness of affectivity and I exploit chiefly long- or everlasting feelings (or emotions) and those which involve the feeling subject more rather than less. I conclude by stating that genuine long-lasting feelings (or emotions) are constitutive of diachronic ontic personal identity. (shrink)

The general concept of a trope – that of a non-shareable character-grounder – admits of a distinction between modifier tropes and module tropes. Roughly, a module trope is self-exemplifying whereas a modifier trope is not. This distinction has wide-ranging implications. Modifier tropes are uniquely eligible to be powers and fundamental determinables, whereas module tropes are uniquely eligible to play a direct role in perception and causation. Moreover, each type of trope theory faces unique challenges concerning character- grounding. Modifier trope theory (...) faces challenges concerning the inscrutability of predication and the incompatibility with bundle theory, whereas module trope theory faces challenges concerning character overdetermination and a collapse into austere nominalism. These differences indicate that the modifier/module distinction divides the advantages of general trope theory and thus presents the trope theorist with a pivotal choice. (shrink)