Evolutionary systems biology (ESB) aims to integrate methods from systems biology and evolutionary biology to go beyond the current limitations in both fields. This article clarifies some conceptual difficulties of this integration project, and shows how they can be overcome. The main challenge we consider involves the integration of evolutionary biology with developmental dynamics, illustrated with two examples. First, we examine historical tensions between efforts to define general evolutionary principles and articulation of detailed mechanistic explanations of specific traits. Next, these (...) tensions are further clarified by considering a recent case from another field focused on developmental dynamics: stem cell biology. In the stem cell case, incompatible explanatory aims block integration. Experimental approaches aim at mechanistic explanation while dynamical system models offer explanation in terms of general principles. We then discuss an ESB case in which integration succeeds: search for general attractors using a dynamical systems framework synergizes with the experimental search for detailed mechanisms. Contrasts between the positive and negative cases suggest general lessons for achieving an integrated understanding of developmental and evolutionary dynamics. The key integrative move is to acknowledge two complementary aims, both relevant to explanation: identifying the space of possible dynamic states and trajectories, and mechanistic understanding of causal interactions underlying a specific phenomenon of interest. These two aims can support one another in a joint project characterizing dynamic aspects of evolving lineages. This more inclusive project can lead to insights that cannot be reached by either approach in isolation. (shrink)

This monograph identifies the essential characteristics of the objects described by current quantum theory and considers their relationship to space-time. In the process, it explicates the senses in which quantum objects may be consistently considered to have parts of which they may be composed or into which they may be decomposed. The book also demonstrates the degree to which reduction is possible in quantum mechanics, showing it to be related to the objective indefiniteness of quantum properties and the strong non-local (...) correlations that can occur between the physical quantities of quantum subsystems. Careful attention is paid to the relationships among such property correlations, physical causation, probability, and symmetry in quantum theory. In this way, the text identifies and clarifies the conceptual grounds underlying the unique nature of many quantum phenomena. (shrink)

Recent work in quantum information science has produced a revolution in our understanding of quantum entanglement. Scientists now view entanglement as a physical resource with many important applications. These range from quantum computers, which would be able to compute exponentially faster than classical computers, to quantum cryptographic techniques, which could provide unbreakable codes for the transfer of secret information over public channels. These important advances in the study of quantum entanglement and information touch on deep foundational issues in both physics (...) and philosophy. This interdisciplinary volume brings together fourteen of the world's leading physicists and philosophers of physics to address the most important developments and debates in this exciting area of research. It offers a broad spectrum of approaches to resolving deep foundational challenges - philosophical, mathematical, and physical - raised by quantum information, quantum processing, and entanglement. This book is ideal for historians, philosophers of science and physicists"--Provided by publisher. (shrink)

Entanglement was initially thought by some to be an oddity restricted to the realm of thought experiments. However, Bell’s inequality delimiting local - behavior and the experimental demonstration of its violation more than 25 years ago made it entirely clear that non-local properties of pure quantum states are more than an intellectual curiosity. Entanglement and non-locality are now understood to figure prominently in the microphysical world, a realm into which technology is rapidly hurtling. Information theory is also increasingly recognized by (...) physicists and philosophers as intimately related to the foundations of mechanics. The clearest indicator of this relationship is that between quantum information and entanglement. To some degree, a deep relationship between information and mechanics in the quantum context was already there to be seen upon the introduction by Max Born and Wolfgang Pauli of the idea that the essence of pure quantum states lies in their provision of probabilities regarding the behavior of quantum systems, via what has come to be known as the Born rule. The significance of the relationship between mechanics and information became even clearer with Leo Szilard’s analysis of James Clerk Maxwell’s infamous demon thought experiment. Here, in addition to examining both entanglement and quantum information and their relationship, I endeavor to critically assess the influence of the study of these subjects on the interpretation of quantum theory. (shrink)

Carl Gustav Hempel (1905-1997) was one of the preeminent figures in the philosophical movement of logical empiricism. He was a member of both the Berlin and Vienna circles, fled Germany in 1934 and finally settled in the US where he taught for many years in New York, Princeton, and Pittsburgh. The essays in this collection come from the early and late periods of Hempel's career and chart his intellectual odyssey from a rigorous commitment to logical positivism in the 1930s (...) (when Hempel allied himself closely with Carnap) to a more sociological approach close in spirit to the work of Neurath and Kuhn. The collection brings together essays which have up till now been difficult to find, four of which are appearing in English for the first time. Cumulatively they offer a fresh perspective on Hempel's intellectual development and on the rise and demise of logical empiricism. (shrink)

This research investigated whether perceived situational appropriateness (defined as the degree of fit between product and intended usage situations) is predictive of consumer choices for foods and beverages, on the theoretical premise that intended usage situation acts as a frame of reference in orienting choices. Extant research on the topic, though suggestive of a link, is very limited in scope and almost completely lacking with regards to choice behaviour (as opposed to other aspects such as food acceptability or intake). To (...) address the hypotheses, data collected in a series of 15 experiments ($N= 2731$ consumers in total) -- covering a wide range of product categories and usage situations -- are presented. In all studies, participants evaluated a set of stimuli varying with respect to perceived appropriateness (low to high), and evaluated each stimulus either monadically using a choice likelihood scale or by performing a discrete choice task. Regression analyses from all studies consistently indicated that perceived appropriateness significantly predicted choice response. The results were robust with respect to variation in product category and experimental protocol and, overall, strongly support the notion that appropriateness can provide a simple yet powerful (in some case accounting for over 50\% of variance) predictor of consumer choice. Effect sizes varied substantially: perceived appropriateness explained from a minimum of 3\% to over 65\% of variance in consumer choice, and this variation was linearly related to the degree of product heterogeneity in the product sets. This research also investigated possible moderators of the link between appropriateness and choice, by relating the results to consumers’ product familiarity and involvement. While both traits significantly (and positively) affected choice, they did not interact with appropriateness. Possible explanations for these results, as well as other possible candidate moderators to explore in future research, are highlighted. (shrink)

This book gives an overview for practitioners and students of quantum physics and information science. It provides ready access to essential information on quantum information processing and communication, such as definitions, protocols and algorithms. Quantum information science is rarely found in clear and concise form. This book brings together this information from its various sources. It allows researchers and students in a range of areas including physics, photonics, solid-state electronics, nuclear magnetic resonance and information technology, in their applied and theoretical (...) branches, to have this vital material directly at hand. (shrink)