DBS Think Tank IX was held on August 25–27, 2021 in Orlando FL with US based participants largely in person and overseas participants joining by video conferencing technology. The DBS Think Tank was founded in 2012 and provides an open platform where clinicians, engineers and researchers can freely discuss current and emerging deep brain stimulation technologies as well as the logistical and ethical issues facing the field. The consensus among the DBS Think Tank IX speakers was that DBS expanded in (...) its scope and has been applied to multiple brain disorders in an effort to modulate neural circuitry. After collectively sharing our experiences, it was estimated that globally more than 230,000 DBS devices have been implanted for neurological and neuropsychiatric disorders. As such, this year’s meeting was focused on advances in the following areas: neuromodulation in Europe, Asia and Australia; cutting-edge technologies, neuroethics, interventional psychiatry, adaptive DBS, neuromodulation for pain, network neuromodulation for epilepsy and neuromodulation for traumatic brain injury. (shrink)

Background: Freezing of gait is a common symptom in Parkinson’s disease and can be difficult to treat with dopaminergic medications or with deep brain stimulation. Novel stimulation paradigms have been proposed to address suboptimal responses to conventional DBS programming methods. Burst-cycling deep brain stimulation delivers current in various frequencies of bursts, while maintaining an intra-burst frequency identical to conventional DBS.Objective: To evaluate the safety and tolerability of BCDBS in PD patients with FOG.Methods: Ten PD subjects with STN or GPi DBS (...) and complaints of FOG were recruited for this single center, single blinded within-subject crossover study. For each subject, we compared 4, 10, and 15 Hz BCDBS to conventional DBS during the PD medication-OFF state.Results: There were no serious adverse events with BCDBS. It was feasible and straightforward to program BCDBS in the clinic setting. The benefit was comparable to conventional DBS in measures of FOG, functional mobility and in PD motor symptoms. BCDBS had lower battery consumption when compared to conventional DBS.Conclusions: BCDBS was feasible, safe and well tolerated and it has potential to be a viable future DBS programming strategy. (shrink)

It is sometimes said that our age is an age of relativism. For example, Paul Tillich has expressed his “uneasiness about the victory of relativism in all realms of thought and life today.” Karl Popper tells us that “the main philosophical malady of our time is an intellectual and moral relativism, the latter being at least in part based on the former.” What Popper refers to as “intellectual relativism” consists in part in a doctrine about truth which is sometimes expressed (...) as “There is no such thing as absolute truth.” At other times it is expressed by saying “truth is relative.”. (shrink)

Psychologism in logic holds that logic is a branch of psychology. This view has been vigorously defended by John Stuart Mill and by a number of German philosophers of logic, notably Erdmann. Its chief critics have been Husserl and Frege and, to a lesser extent, Russell. Husserl set forth a profound and detailed critique of psychologism in Logical Investigations. This paper examines this critique. First, I explain why the psychologistic theory is attractive. Then I show that Husserl's critique is not (...) convincing, partly because he does not take the theory in its most plausible form and partly because he ignores certain important distinctions (for example, between what a statement is about and what it is true in virtue of). Then I raise two new objections to the psychologistic theory. The purpose of this paper is to suggest that the psychologistic theory remains an important and serious position from which we can learn much about the status of logic. (shrink)

This paper first explains why the charge of self-refutation against extreme relativism is so important and then defends extreme relativism against two of the most recent and most sophisticated accusations of self-refutation. It is shown that these accusations seem plausible only because they illicitly employ principles appropriate only to absolute truth; hence these accusations are unsound. One central topic of discussion in the paper is the relation between "a believes that p" and "p is true for a".

This article challenges the current scholarly consensus that Suetonius wrote the Divus Iulius regardless of Plutarch. Closer examination of the Caesar-biographies shows which influence Plutarch has exerted by his biographic works on Suetonius and reveals that the dominant position in the classical studies is obsolete. This paper scrutinises not only clearly defined knowledge of the Quellenforschung, but illuminates also the role model of Plutarch. Before it is possible to assess the dependence of the Divus Iulius from the Καισαρ, I will (...) reopen the case of the composition dates, examine the literary circles as a space of interaction and look on Plutarch’s reception in Rome. (shrink)

This paper first explains why the charge of self-refutation against extreme relativism is so important and then defends extreme relativism against two of the most recent and most sophisticated accusations of self-refutation. It is shown that these accusations seem plausible only because they illicitly employ principles appropriate only to absolute truth; hence these accusations are unsound. One central topic of discussion in the paper is the relation between "a believes that p" and "p is true for a".

In his valuable book [3], Israel Scheffler presents an extended critique of Thomas Kuhn's philosophy of science. Scheffler argues against Kuhn's “main thesis,” namely that “... paradigm change in science is not generally subject to deliberation and critical assessment”. Scheffler does recognize, though, that there are important elements of Kuhn's view that themselves seem to conflict with this “main thesis.” For these elements seem to make possible deliberation, critical assessment, and objectivity in the discussion of scientific paradigms. So it appears (...) from Scheffler's critique that Kuhn's position is inconsistent. The puzzle is compounded by Kuhn's admission—indeed, insistence—that his book does contain “a preliminary codification of good reasons for theory choice. These are... reasons of exactly the kind standard in philosophy of science: accuracy, scope, simplicity, fruitfulness, and the like”. In his recent reply to Kuhn, Scheffler quotes this passage from Kuhn and says: “If these reasons are not... to be construed as utterly free of all constraints or themselves paradigm-dependent, then they allow the comparison of rival paradigms and make paradigm debates intelligible. Such intelligibility is, however, at odds with Kuhn's statement that the proponents of competing paradigms ‘will inevitably talk through each other’”. In this interchange between Scheffler and Kuhn, one gets the impression of people, if not paradigms, talking “through each other.” I think that this nonmeeting of minds is due to interpreting Kuhn as an opponent of objectivity when in fact he is not an opponent but a proponent. It is this misinterpretation which produces the apparent inconsistency in Kuhn's position. In this paper I suggest a way of understanding Kuhn which resolves this apparent inconsistency in his work and might help to focus discussion on the real issue between Kuhn and many of his critics. This suggestion has the crucial consequence of shifting the focus from objectivity to the real issue, namely truth. (shrink)

Despite seemingly ambiguous writings, Beard is a relativist. Beard states that if historical conceptions are relative, then relativity is relative; this is not a rejection of relativism. As times change, doctrines become outmoded. Beard's times were right for relativism, so he was a relativist, despite his knowledge of its eventual demise. Relativism cannot provide the historian with a frame of reference to interpret the "totality of history." He must choose a comprehensive and informed frame. Beard seems to indicate that historians (...) can forecast the future; yet, this contradicts his rejection of absolute historical truths. He is not discussing forecasting future events, but forecasting future frames of reference. (shrink)

Red-2 is a computer program for red-cell antibody identification, a piece of "normal science". Abstracting from Red-2, a general problem solving mechanism is described that is especially suited for performing a form of abductive inference or best explanation finding. A problem solver embodying this mechanism synthesizes composite hypotheses by combining hypothesis parts. This is a common task of intelligence, and a component of scientific reasoning. The work addresses the question, 'How is science possible?' by showing how a simple but powerful (...) form of hypothesis synthesis is computationally feasible. (shrink)

EDITORS NOTE: Typographical corrections of page proofs were accidentally left out of Dr. Beach's article, which appeared in the January issue of this volume. The omission diminishes the value of the article; and the Editor apologizes for the oversight to Dr. Beach and the readers of Metaphilosophy. A typographically correct version is given below.

EDITORS NOTE: Typographical corrections of page proofs were accidentally left out of Dr. Beach's article, which appeared in the January issue of this volume. The omission diminishes the value of the article; and the Editor apologizes for the oversight to Dr. Beach and the readers of Metaphilosophy. A typographically correct version is given below.