ObjectiveTo identify the ethical challenges associated with the development and implementation of new tuberculosis drugs and diagnostics.MethodsTwenty-three semi-structured qualitative interviews conducted between December 2015 and September 2016 with programme administrators, healthcare workers, advocates, policymakers, and funders based in the Americas, Europe, and Africa. Interviews were analysed using thematic analysis.ResultsDivergent interests and responsibilities, coupled with power imbalances, are a primary source of ethical challenges; the uncertain risk profiles of new drugs present an additional one. Although this challenge can be partially mitigated (...) through stringent pharmacovigilance, respondents highlighted that high-burden countries tend to lack the resources to facilitate safe implementation. Increased advocacy and community engagement are considered an ethical imperative for future TB development and implementation.ConclusionsThis project helps identify some of the ethical challenges of new TB technologies. It demonstrates that investigating ethical challenges through qualitative research is one way to apprehend the difficulty of implementing new TB technologies. Addressing this difficulty will require that those in positions of power reconsider their interests in relation to disempowered communities.Policy implicationsEfforts to build consensus regarding what values should underpin the global governance of TB research, prevention, and care are essential to facilitate the ethical implementation of new TB technologies. (shrink)

This paper argues that international development research should be submitted to the oversight of research ethics committees from the countries where data will be collected. This includes research conducted by individuals who may fall outside the jurisdictions of most ethics guidelines or policies, such as individuals contracted by non-governmental organizations. The argument is grounded in an understanding of social justice that recognizes that not seeking local ethics approval can be an affront to the decolonization movement, and may lead to significant (...) direct harms to participants. Local ethics oversight can help ensure projects appropriately take into consideration local laws, regulations, priorities and context. For example, a local research ethics committee may be in a better position than a foreign one to assess whether any given proposed project carries context-specific risks. In addition, submitting to a local research ethics committee is to acknowledge the legitimacy of local authorities, thereby taking a stance against the history of colonizing disempowerment. Local oversight is a mechanism to increase the accountability of researchers working abroad: if respect for local authority and tailoring to local context are to be upheld, there must be mechanisms to ensure that research that does not meet these requirements does not proceed. Objections based on the limited oversight capacity in some countries and on concerns related to the politicization of the review process are discussed. Finally, the roles and responsibilities of the various stakeholders in the implementation of greater local ethics oversight are laid out. (shrink)

Developing Global Health Programming: A Guidebook for Medical and Professional Schools , edited by Jessica Evert, Paul Drain, and Thomas Hall, is reviewed. In spite of some editorial shortcomings, the book is a terrific aggregation of resources and reflections on the state of global health education that leaves readers with a multitude of useful and diverse tools, as well as directions about where to find additional ones.

Prominent tuberculosis (TB) actors are invoking solidarity to motivate and justify collective action to address TB, including through intensified development and implementation (D&I) of technologies such as drugs and diagnostics. We characterize the ethical challenges associated with D&I of new TB technologies by drawing on stakeholder perspectives from 23 key informant interviews and we articulate the ethical implications of solidarity for TB technology D&I. The fundamental ethical issue facing TB technological D&I is a failure within and beyond the TB community (...) to stand in solidarity with persons with TB in addressing the complex sociopolitical contexts of technological D&I. The failure in solidarity relates to two further ethical challenges raised by respondents: skewed power dynamics that hinder D&I and uncertainties around weighing risks and benefits associated with new technologies. Respondents identified advocacy and participatory research practices as necessary to address such challenges and to motivate sustained collective action to accelerate toward TB elimination. We present the first empirical examination of bioethical accounts of solidarity in public and global health. Our study suggests that solidarity allows us better to understand and address the ethical challenges that arrest the D&I of new TB technologies. Solidarity lends credence to policies and practices that address the relational nature of illness and health through collective action. (shrink)

The conduct of research in settings affected by disasters such as hurricanes, floods and earthquakes is challenging, particularly when infrastructures and resources were already limited pre-disaster. However, since post-disaster research is essential to the improvement of the humanitarian response, it is important that adequate research ethics oversight be available. We aim to answer the following questions: 1) what do research ethics committee members who have reviewed research protocols to be conducted following disasters in low- and middle-income countries perceive as the (...) key ethical concerns associated with disaster research?, and 2) in what ways do REC members understand these concerns to be distinct from those arising in research conducted in non-crisis situations? This qualitative study was developed using interpretative description methodology; 15 interviews were conducted with REC members. Four key ethical issues were identified as presenting distinctive considerations for disaster research to be implemented in LMICs, and were described by participants as familiar research ethics issues that were amplified in these contexts. First, REC members viewed disaster research as having strong social value due to its potential for improving disaster response, but also as requiring a higher level of justification compared to other research settings. Second, they identified vulnerability as an overarching concern for disaster research ethics, and a feature that required careful and critical appraisal when assessing protocols. They noted that research participants’ vulnerabilities frequently change in the aftermath of a disaster and often in unpredictable ways. Third, they identified concerns related to promoting and maintaining safety, confidentiality and data security in insecure or austere environments. Lastly, though REC members endorsed the need and usefulness of community engagement, they noted that there are significant challenges in a disaster setting over and above those typically encountered in global health research to achieve meaningful community engagement. Disaster research presents distinctive ethical considerations that require attention to ensure that participants are protected. As RECs review disaster research protocols, they should address these concerns and consider how justification, vulnerability, security and confidentially, and community engagement are shaped by the realities of conducting research in a disaster. (shrink)

Disaster research has grown in scope and frequency. Research in the wake of disasters and during humanitarian crises – particularly in resource-poor settings – is likely to raise profound and unique ethical challenges for local communities, crisis responders, researchers, and research ethics committees. Given the ethical challenges, many have questioned how best to provide research ethics review and oversight. We contribute to the conversation concerning how best to ensure appropriate ethical oversight in disaster research and argue that ethical disaster research (...) requires of researchers and RECs a particular sort of ongoing, critical engagement which may not be warranted in less exceptional research. We present two cases that typify the concerns disaster researchers and RECs may confront, and elaborate upon what this ongoing engagement might look like – how it might be conceptualized and utilized – using the concept of real-time responsiveness. The central aim of RTR, understood here as both an ethical ideal and practice, is to lessen the potential for research conducted in the wake of disasters to create, perpetuate, or exacerbate vulnerabilities and contribute to injustices suffered by disaster-affected populations. Well cultivated and deployed, we believe that RTR may enhance the moral capacities of researchers and REC members, and RECs as institutions where moral agency is nurtured and sustained. (shrink)

The American Journal of Bioethics, Volume 11, Issue 10, Page 24-26, October 2011.

Imagine that you are part of the editorial board of a young bioethics journal committed to publishing open access (OA) and to ensuring accessibility to high quality and innovative scholarship. To support junior and interna- tional scholars who might not otherwise find places for their work in the leading Western bioethics journals, you do not charge author fees. Imagine also that you have no financial resources to pay for a professional website, auto- mated submissions manager, or even a part-time coordina- (...) tor: Your government has cut all grants for journals, you cannot go to industry for private funding because of the evident risk of apparent conflicts of interest, and your strapped-for-cash institution cannot afford to offer you any support. If one of the major publishers were to approach you to sign a deal, the temptation would be strong to accept. However, this would likely mean putting aside your ideals: It would be impossible to stay a “Green OA” publication (i.e., free of author publication charges) or supportive of junior and international scholars (because of pressures to “increase credibility” through artificially high rejection rates, for example). (shrink)

Les textes du recueil Quand le geste fait sens sont pour partie issus d’un colloque, pour partie rédigés directement pour cette publication. Outre une Préface de Renaud Barbaras et une Introduction de Lucia Angelino, le volume comporte neuf études. Il est dépourvu d’index. Ces études sont réunies sous la bannière de l’expression « le geste f...

Les textes du recueil Quand le geste fait sens sont pour partie issus d’un colloque, pour partie rédigés directement pour cette publication. Outre une Préface de Renaud Barbaras et une Introduction de Lucia Angelino, le volume comporte neuf études (une consacrée à la danse, quatre à la musique, une au jeu, une à l’art conceptuel, deux à la vie et à la philosophie envisagées comme des performances). Il est dépourvu d’index. Ces études sont réunies sous la bannière de l’expression (...) « le geste f... (shrink)

La philosophie de Souriau a pour objet ce qu’il appelle les existences virtuelles, un mode d’existence fragile et précaire qui concerne tout processus d’instauration. Ces virtualités sont en état d’abaliété, elles existent « en et par autre chose », de manière relationnelle et indéterminée. Ces particularités ontologiques posent un problème de connaissance : celui de connaître de telles singularités, aussi appelées « âmes ». De nouveaux outils, issus de l’esthétique, accompagnent la connaissance. La fiction et la dramatisation viennent jouer un (...) rôle épistémique. Les êtres de fiction, qui existent selon un mode spécifique d’existence, font naître un sentiment esthétique, qui devient la base créatrice de la philosophie et de la connaissance. (shrink)

In this article, I seek to make sense of the oft-invoked idea of ‘public emergency’ and of some of its radical moral implications. I challenge controversial claims by Tom Sorell, Michael Walzer, and Giorgio Agamben, and argue for a more discriminating understanding of the category and its moral force.

This paper delves into the work of Clive L. Spash, a British radical ecological economist well-known in his field who currently holds a professorship at the Vienna University of Economics and Business. We start with an examination of the principles of his “social ecological economics.” We then critically evaluate his attack on economic growth and his perspective on the standard economic models of climate change. Lastly, we explore his approach to science as a theoretical pursuit and his policy recommendations. The (...) first version of this paper was given as a keynote lecture at the 7th Austrian Economics Meeting Europe, May 12-13, 2023, Université Catholique de l’Ouest, Angers, France, and a second version at the Summer University in Political Economy, July 20-22, 2023, Aix-Marseille University, France. I wish to thank the organizers of these conferences, and also the anonymous referees whose remarks have been taken into account to improve the paper. (shrink)

Peu à peu, tandis que Virgile achève la description ethnographique de la ruche, un glissement s’opère dans son propos : il célèbre d’abord la chasteté des abeilles, et le renouvellement de l’espèce par une miraculeuse génération spontanée ; il explique ensuite leur admirable organisation sociale par un lien privilégié avec la divinité, puisque les abeilles posséderaient une « parcelle d’intelligence divine » ; après ce bref aperçu d’une mystique panthéiste, i...

_Desire and Distance_ constitutes an important new departure in contemporary phenomenological thought, a rethinking and critique of basic philosophical positions concerning the concept of perception presented by Husserl and Merleau-Ponty, though it departs in significant and original ways from their work. Barbaras's overall goal is to develop a philosophy of what "life" is—one that would do justice to the question of embodiment and its role in perception and the formation of the human subject. Barbaras posits that desire and distance inform (...) the concept of "life." Levinas identified a similar structure in Descartes's notion of the infinite. For Barbaras, desire and distance are anchored not in meaning, but in a rethinking of the philosophy of biology and, in consequence, cosmology. Barbaras elaborates and extends the formal structure of desire and distance by drawing on motifs as yet unexplored in the French phenomenological tradition, especially the notions of "life" and the "life-world," which are prominent in the later Husserl but also appear in non-phenomenological thinkers such as Bergson. Barbaras then filters these notions through Merleau-Ponty. (shrink)

In this article, I seek to make sense of the oft-invoked idea of 'public emergency' and of some of its (supposedly) radical moral implications. I challenge controversial claims by Tom Sorell, Michael Walzer, and Giorgio Agamben, and argue for a more discriminating understanding of the category and its moral force.

This paper investigates how and when pairs of terms such as “local–global” and “im Kleinen–im Grossen” began to be used by mathematicians as explicit reflexive categories. A first phase of automatic search led to the delineation of the relevant corpus, and to the identification of the period from 1898 to 1918 as that of emergence. The emergence appears to have been, from the very start, both transdisciplinary (function theory, calculus of variations, differential geometry) and international, although the AMS-Göttingen connection played (...) a specific part. First used as an expository and didactic tool (e.g. by Osgood), it soon played a crucial part in the creation of new mathematical concepts (e.g. in Hahn’s work), in the shaping of research agendas (e.g. Blaschke’s global differential geometry), and in Weyl’s axiomatic foundation of the manifold concept. We finally turn to France, where in the 1910s, in the wake of Poincaré’s work, Hadamard began to promote a research agenda in terms of “passage du local au general.”. (shrink)

The same subjectivity that makes the world appear belongs, as an integral part, to that which it makes appear, so that there is no alternative between the phenomenological involvement of the world by subjectivity and the ontological involvement of subjectivity by the world. These are the two faces, already abstract, of a fundamental and original situation, in other words, a primitive fact or an archifact. We have thus transported the correlation to the terrain of the world in the form of (...) a double position of the subject, which I have further formulated metaphorically through the distinction between being before and being within. So, what does it mean to belong to the world, or rather, what are the senses of belonging implied by the fundamental situation we have just described? (shrink)

This paper examines Plato’s views about the unity of argument and drama, and asks why Plato never made his views on this unity fully explicit. Taking the Gorgias as a case study it is argued that unity rests on the conception of refutative dialectic as justice and on the principle of self-consistency of thought and desire. As compared to the treatise, the dialogue form has the advantage of being able to defend these substantive views in action and thus to demonstrate (...) the performative contradictions in the ideas of one’s opponents. (shrink)

La notion d'espace sonore est devenue de plus en plus prégnante dans le domaine musical, plus particulièrement dans la musique électroacoustique. Mais comment la définir? Cette simple interrogation, dont la réponse semble évidente soulève cependant, lorsqu'elle est approfondie, une multitude d'ambiguïtés, sources de nouvelles réflexions. Comment l'écoute appréhende-t-elle l'espace? Comment s'immerge-t- elle en lui? Qu'appréhende-t-on lorsqu'on écoute? Et finalement, qu'est-ce qu'un son? Quelles en sont les limites spatiales et temporelles? Lorsque l'écoute se confronte à l'espace sonore, où se situe la (...) frontière entre perception et imagination? Tout au long du présent ouvrage, l'auteur essaie de mettre en évidence l'empreinte effective de l'écoute dans la structuration de l'espace. Il tente de montrer, en s'appuyant sur les théories esthétiques, pourquoi l'espace n'est pas pris en compte par les pensées sur la musique avant le XXe siècle. A partir de cette observation et des dernières recherches phénoménologiques de Maurice Merleau-Ponty, il met en lumière le rôle essentiel du corps de l'auditeur dans notre perception de l'espace. Ensuite, il témoigne de la façon dont les compositeurs, à partir de la seconde moitié du XXe siècle et jusqu'à aujourd'hui, n'ont cessé de développer une implication active de l'écoute, ce qui a progressivement favorisé l'émergence d'un espace musical dynamique et mouvant. Puis, au terme de sa réflexion, à l'aide des travaux sur l'énaction du neurobiologiste Francisco J. Varela, Renaud Meric s'emploie à reconstruire le lien esthétique étroit entre l'espace, l'écoute et l'imagination, lien encore peu examiné, pourtant fondamental pour comprendre notre relation complexe à la musique. (shrink)

Depuis son retour, j’étais rongé. J’abrégeais les conversations, évitais son regard. Malgré tous mes efforts pour paraître naturel, pour faire comme si de rien n’était, je sentais bien, piètre comédien, que chaque phrase sonnait faux, que chaque geste suintait la culpabilité. Dans ses yeux, la perplexité initiale fit bien vite place au soupçon, et ma feinte bonne humeur fut démantelée sans coup férir par d’éloquents silences, froids appels à cesser toute mascarade. Enferré comme je l’étais, a..

La quatrième Géorgique n’est pas le simple entrelacs d’une didactique et d’une esthétique délicate et raffinée. Un troisième fil complique et parachève la tresse : la description ethnographique de la vie des abeilles. Il n’est plus question de conseiller l’apprenti apiculteur ; Virgile change de registre, et rend compte scrupuleusement de l’organisation sociale de la ruche. On a pu parler à ce propos de « communiste monarchique » : les abe...

Comment se représenter sa propre vie ? Comment se figurer le déroulé des ans, tracer la ligne qui passe par tous les points saillants de notre mémoire et englobe les plages d’oubli qui nous firent, elles aussi, ce que nous sommes ? Plusieurs formes, plusieurs « patrons » sont à notre disposition. En premier lieu, le biologique : le compte des années superpose les visions d’un corps en croissance, puis en déclin, les mutations successives qui l’affectent, les marques qui s’y (...) inscrivent. S’y aj.. (shrink)

La première partie du livre IV met apparemment en œuvre le programme didactique des Géorgiques, Virgile multipliant les conseils à l’apiculteur, quant au choix du lieu pour la ruche, à la sélection des espèces, aux aliments à mettre à disposition, à la récolte du miel, mais surtout aux précautions à prendre pour éloigner les abeilles des nombreux dangers potentiels qui les menacent, qu’il s’agisse du climat trop rigoureux ou de prédateu...

Can the state, as opposed to its individual human members in their personal capacity, intelligibly seek to avoid blame for unjustified wrongdoing by invoking excuses (as opposed to justifications)? Insofar as it can, should such claims ever be given moral and legal recognition? While a number of theorists have denied it in passing, the question remains radically underexplored. -/- In this article (in its penultimate draft version), I seek to identify the main metaphysical and moral objections to state excuses, and (...) begin to investigate their strength. I work from the ecumenical assumption that general understandings of modern states as group moral agents proper or as mere fictional points of imputation for individual behaviour are both plausible, and that the question of state excuses should be asked in terms of both paradigms. Issues addressed include: the lack of state consciousness/affect, the nature and relevance of developmental and executive defects in group agents, the value of state interests and how interests relate to plausible claims of excuses, the shortfall of responsibility argument for group responsibility and its interface with state excuses, the symbolic and consequential (dis)value that state excuses may have, as well as concerns that states are entities that should live up to outstandingly high virtuous standards of impartiality and equanimity. -/- I conclude that even if the range of excuses available to states does not overlap neatly with excuses available to ordinary individuals, some excuses may still be morally available to states. More generally, I emphasize the need for a systematic discussion of group excuses writ large, and of their relationship with the wider question of when group entities may legitimately be singled out to bear adverse normative consequences for wrongdoing. (shrink)

In this paper, I seek to close a gap in Michael Walzer’s argument for the moral equality of soldiers. Specifically, I seek to show that Walzer’s argument for the moral equality of soldiers depends upon an implicit analysis of the function of excuses. I provide this analysis of excuses: a triadic relationship between moral norms, a background of normality and excuses. I then use this analysis to show that Jeff McMahan’s argument for the moral inequality of soldiers rest upon an (...) implausible view of excuses, namely that the conditions of war merely constitute excuses for failing to comply with ordinary, or peacetime, morality. I argue that the conditions of war are best understood as providing a new background of normality rather than a set of excuses. To show this, I identify five conditions that separate the normality of war from the normality of peace. (shrink)

Historically, all societies have used comparison to analyze cultural difference through the interaction of religion, power, and translation. When comparison is a self-reflective practice, it can be seen as a form of comparatism. Many scholars are concerned in one way or another with the practice and methods of comparison, and the need for a cognitively robust relativism is an integral part of a mature historical self-placement. This volume looks at how different theories and practices of writing and interpretation have developed (...) at different times in different cultures and reconsiders the specificities of modern comparative approaches within a variety of comparative moments. The idea is to reconsider the specificities, the obstacles, and the possibilities of modern comparative approaches in history and anthropology through a variety of earlier and parallel comparative horizons. Particular attention is given to the exceptional role of Athens and Jerusalem in shaping the Western understanding of cultural difference. (shrink)