Asking people to discover the identity of a recognition test probe immediately before making a recognition judgment increases the probability of an old judgment. To inform theories of this “revelation effect,” event-related potentials were recorded for revealed and intact test items across two experiments. In Experiment 1, we used a revelation effect paradigm where half of the test probes were presented as anagrams and the other items were presented intact. The pattern of ERP results from this experiment suggested that revealing (...) an item decreases initial familiarity levels and caused the revealed items to elicit similar levels of activity. In Experiment 2, half of the probes were preceded by an addition task . The pattern of ERP effects in this study were distinct from those observed in Experiment 1. More specifically, revealed item ERPs were more negative than intact ERPs at frontal electrodes and more positive at parietal electrodes early in the interval. Later in the epoch, revealed item ERPs were more negative than intact items. These data suggest that related tasks decrease familiarity and alter the signal-to-noise ratio of old and new items, whereas unrelated tasks affect processing in a different way that also results in the revelation effect. The implications for current theories of the revelation effect are discussed. (shrink)

ABSTRACT:In 2010,Business Ethics Quarterlypublished ten articles that considered the potential contributions to business ethics research arising from recent scholarship in a variety of philosophical and social scientific fields (strategic management, political philosophy, restorative justice, international business, legal studies, ethical theory, ethical leadership studies, organization theory, marketing, and corporate governance and finance). Here we offer short responses to those articles by members ofBusiness Ethics Quarterly’s editorial board and editorial team.

Strong evidence exists in the literature that remembering to complete intentions involves executive processing subserved by the frontal lobes. Event-related potentials were measured during the encoding of actions with the intention to perform versus more neutral material about which there was no such intentionality. Event-related potentials were also measured in a two-alternative discrimination task requiring identification of the to-be-performed actions and to-be-memorized actions. The results suggest that formation and retrieval of intentions differs from encoding and retrieval of similar material committed (...) to memory. Additionally, the results suggest that right frontal areas may play an important role in the formation of prospective actions and that intentions are kept active in memory by processing mediated by the left frontal pole. (shrink)

One approach to validating simulation models is to formally compare model outputs with independent data. We consider such model validation from the point of view of Frequentist statistics. A range of estimates and tests of goodness of fit have been advanced. We review these approaches, and demonstrate that some of the tests suffer from difficulties in interpretation because they rely on the null hypothesisHypothesis that the model is similar to the observationsObservations. This reliance creates two unpleasant possibilities, namely, a model (...) could be spuriously validated when dataData are too few, or inappropriately rejected when data are too many. Finally, these tests do not allow a principled declaration of what a reasonable level of difference would be considering the purposes to which the model will be put. We consider equivalence tests, and demonstrate that they do not suffer from the previously identified shortcomings. We provide two case studies to illustrate the claims of the chapter. (shrink)

Despite a large and multifaceted effort to understand the vast landscape of phenotypic data, their current form inhibits productive data analysis. The lack of a community-wide, consensus-based, human- and machine-interpretable language for describing phenotypes and their genomic and environmental contexts is perhaps the most pressing scientific bottleneck to integration across many key fields in biology, including genomics, systems biology, development, medicine, evolution, ecology, and systematics. Here we survey the current phenomics landscape, including data resources and handling, and the progress that (...) has been made to accurately capture relevant data descriptions for phenotypes. We present an example of the kind of integration across domains that computable phenotypes would enable, and we call upon the broader biology community, publishers, and relevant funding agencies to support efforts to surmount today's data barriers and facilitate analytical reproducibility. (shrink)

Recollection is sometimes automatic in that details of a prior encounter with an item come to mind although those details are irrelevant to a current task. For example, when asked about the size of the type in which an item was earlier presented, one might automatically recollect the location in which it was presented. We used the process dissociation procedure to show that such noncriterial recollection can function as familiarity—its effects were independent of intended recollection.

Threshold- and signal-detection-based models have dominated theorizing about recognition memory. Building upon these theoretical frameworks, we have argued for a dual-process model in which conscious recollection and familiarity contribute to memory performance. In the current paper we assessed several memory models by examining the effects of levels of processing and the number of presentations on recognition memory receiver operating characteristics . In general, when the ROCs were plotted in probability space they exhibited an inverted U shape; however, when they were (...) plotted inzspace they exhibited a U shape. An examination of the ROCs showed that the dual-process model could account for the observed ROCs, but that models based solely on either threshold or signal-detection processes failed to provide a sufficient account of the data. Furthermore, an examination of subjects' introspective reports using the remember/know procedure showed that subjects were aware of recollection and familiarity and were able to consistently report on their occurrence. The remember/know data were used to accurately predict the shapes of the ROCs, and estimates of recollection and familiarity derived from the ROC data mirrored the subjective reports of these processes. (shrink)

The growth factor progranulin (PGRN) regulates cell division, survival, and migration. PGRN is an extracellular glycoprotein bearing multiple copies of the cysteine‐rich granulin motif. With PGRN family members in plants and slime mold, it represents one of the most ancient of the extracellular regulatory proteins still extant in modern animals. PRGN has multiple biological roles. It contributes to the regulation of early embryogenesis, to adult tissue repair and inflammation. Elevated PGRN levels often occur in cancers, and PGRN immunotherapy inhibits the (...) growth of hepatic cancer xenografts in mice. Recent studies have demonstrated roles for PGRN in neurobiology. An autosomal dominant mutation in GRN, the gene for PGRN, leads to neuronal atrophy in the frontal and temporal lobes, resulting in the disease frontotemporal lobar dementia. In this review we will discuss current knowledge of the multifaceted biology of PGRN. (shrink)

Although death statutes permitting physicians to declare brain death are relatively uniform throughout the United States, academic debate persists over the equivalency of human death and brain death. Alan Shewmon showed that the formerly accepted integration rationale was conceptually incomplete by showing that brain-dead patients demonstrated a degree of integration. We provide a more complete rationale for the equivalency of human death and brain death by defending a deeper understanding of the organism as a whole and by using a novel (...) strategy with shared objectives to justify death determination criteria. Our OaaW account describes different types of OaaW, defining human death as the loss of status as a human OaaW. We defend human death as similar to nonhuman death in terms of wakefulness, but also distinct in terms of the sui generis properties, particularly conscious awareness. We thereby defend the equivalency of brain death and human death using a resulting neurocentric rationale. (shrink)

Natural scientists have proposed that humankind has entered a new geologic epoch. Termed the “Anthropocene,” this new reality revolves around the central role of human activity in multiple Earth ecosystems. That challenge requires a rethinking of social science explanations of organization and environment relationships. In this article, we discuss the need to politicize institutional theory as a means understanding “Anthropocene Society,” and in turn what that resultant society means for the Anthropocene in the natural environment. We modify the constitutive elements (...) of institutional orders and a set of main change mechanisms to explore three scenarios around which future Anthropocene Societies might be built—Collapsing Systems, Market Rules, and Cultural Re-Enlightenment. Simultaneously, we use observations from the Anthropocene to expose limitations in present institutional theory and propose extensions to remedy them. Overall, this article challenges organizational scholars to consider a new paradigm under which research in environmental sustainability and social sustainability takes place. (shrink)

This study in cross-cultural hermeneutics examines the role that modern, Western philosophy has played in the interpretation of Nagarjuna's Madhyamikakarika, a second-century Indian-Buddhist text. Tuck locates a structure of distinct phases or "styles" in modern, philosophical history. These phases, Tuck shows, exhibit discontinuous interpretive biases, as well as continuity of hermeneutic intention. Discovering in each philosophical era a chaacteristic attitude towards the text--whether privilege, objectivity, or neutrality--Tuck argues that the continual reinterpretation of earlier scholarly readings is in fact at the (...) core of fruitful hermeneutic pursuit. (shrink)

Observing averted eye gaze results in the automatic allocation of attention to the gazed-at location. The role of the orientation of the face that produces the gaze cue was investigated. The eyes in the face could look left or right in a head-centred frame, but the face itself could be oriented 90 degrees clockwise or anticlockwise such that the eyes were gazing up or down. Significant cueing effects to targets presented to the left or right of the screen were found (...) in these head orientation conditions. This suggests that attention was directed to the side to which the eyes would have been looking towards, had the face been presented upright. This finding provides evidence that head orientation can affect gaze following, even when the head orientation alone is not a social cue. It also shows that the mechanism responsible for the allocation of attention following a gaze cue can be influenced by intrinsic object-based (i.e. head-centred) properties of the task-irrelevant cue. (shrink)

Source [1] Andrew E. P. Mitchell, Federica Galli, Sondra Butterworth. (2023). Editorial: Equality, diversity and inclusive research for diverse rare disease communities. Front. Psychol., vol. 14. doi:10.3389/fpsyg.2023.1285774. "It is also important to recognize that certain mental health disorders are classified as rare conditions and have their own cultural concepts of distress, as defined in the DSM-5 (American Psychiatric Association, 2013)" and require “equal attention and support for individuals and their families, both physically and emotionally”. [1].

This article takes a conceptual approach to an issue of pedagogical relevance—the presence of teaching and learning moments within educational environments. We suggest sources of philosophical confusions that design patterns for the classification and creation of typologies of classroom events. We identify three foundational assumptions with the way in which classroom events are analyzed: Describing a classroom event ; Devising a procedure for co-classifying events ; Repurposing decontextualized events to fit a preferred analytic model. Hitherto these assumptions have obscured the (...) phenomenal integrity of the learning environment; since the topic sought is based on critical incidents according to analysts’ interests, but not on the actual identifying details of the setting as made available by the participants. While teaching and learning moments are generic issues, in methodological terms these matters have to be explored in their details. In our article, we align ourselves with particular research approaches, namely ethnomethodology and conversation analysis, that facilitate close analysis of ‘perspicuous settings’, such as classroom interactions, through which phenomena such as teaching and learning moments are made visible as collaborative accomplishments. (shrink)

Jonathan Quong Ethics, 119, 507–537 has recently argued that the permissibility of killing innocent threats turns on a distinction between eliminative and opportunistic agency. When we kill bystanders we view them under the guise of opportunism by using them as mere survival tools, but when we kill threats we simply eliminate them. According to Quong, the distinction between opportunistic and eliminative agency reveals that there are two different ways of killing someone as a means to save your own life. Call (...) this the Means Distinction. In this note, I argue that although the Means Distinction seems prima facie plausible it is not a sufficient explanation for the permissibility of killing threats. My argument against the Means Distinction is two-fold. Most non-consequentialists accept that the Means Distinction carries some moral significance, but I argue that this is a mistake: we do not have any reason to believe that opportunistic killings are, in general, worse than eliminative killings. Following this, I argue that even if we accept the Means Distinction, there are threat-type scenarios in which there is no intuitive difference between killing a threat opportunistically and killing a threat eliminatively. (shrink)

Aggleton & Brown argue that a hippocampal-anterior thalamic system supports the “recollection” of contextual information about previous events, and that a separate perirhinal-medial dorsal thalamic system supports detection of stimulus “familiarity.” Although there is a growing body of human literature that is in agreement with these claims, when recollection and familiarity have been examined in amnesics using the process dissociation or the remember/know procedures, the results do not seem to provide consistent support. We reexamine these studies and describe the results (...) of an additional experiment using a receiver operating characteristic (ROC) technique. The results of the reanalysis and the ROC experiment are consistent with Aggleton & Brown's proposal. Patients with damage to both regions exhibit severe deficits in recollection and smaller, but consistent, deficits in familiarity. (shrink)

Husserl's proposed method for knowing the essences of universals, which he calls “free variation,” has been widely criticized for involving viciously circular reasoning. In this paper, I review existing attempts to resolve this problem, and I argue that they all fail. I then show that extant accounts are all guilty of a common mistake: they assume that circularity is inevitable as long as the exercise of free variation presupposes the ability to identify the universal whose essence is in question, that (...) is, the ability to recognize entities as instances of it. I reject this assumption: I argue on both Husserlian and independent philosophical grounds that knowledge of a universal's essence is not required for identifying it, but only for re‐identifying it at every possible world in which it is instantiated. I then defend a reading on which free variation's purpose is to move its practitioner from non‐essentialistic knowledge of a universal's identity (its actual instantiation‐pattern) to essentialistic knowledge of its transworld identity (its instantiation‐pattern in every possible world in which it is present). And I show that such a transformation is a non‐circular progression from non‐modal to modal knowledge. (shrink)

Sweeping denials of the story's capacity to accurately reflect the past are ever catalyzing equally misleading global affirmations. The impositionalists, such as theorist Hayden White, view historical narratives as imposing a falsifying narrative structure on the past, and conclude that narratives cannot be true. Plot-reifiers, such as Alasdair MacIntyre, David Carr, and Frederick Olafson, posit that the past is already narratively structured; historical plots are reified in order for there to be something in the world to which narrative structures can (...) correspond in being true. The antireferentialists such as JeanFrançois Lyotard and Roland Barthes deny that narrative histories even claim truth. Escaping this trilemma of theoretical interpretation involves accepting the idea that construction of a history does not entail its falsification. Historical narrative need to be allowed to function both figurally, in the sense of generating new discursive figures, and at the same time literally, in the sense of asking to be understood literally. Narratives need to be understood on their own terms, and not treated as an approximation to some foreign ideal. (shrink)

First responders to chemical, biological, radiological, or nuclear (CBRN) events face decisions having significant human consequences. Some operational decisions are supported by standard operating procedures, yet these may not suffice for ethical decisions. Responders will be forced to weigh their options, factoring-in contextual peculiarities; they will require guidance on how they can approach novel (indeed unique) ethical problems: they need strategies for “on the spot” ethical decision making. The primary aim of this paper is to examine how first responders should (...) approach on the spot ethical decision-making amid the stress and uncertainty of a CBRN event. Drawing on the long-term professional CBRN experience of one of the authors, this paper sets out a series of practical ethical dilemmas potentially arising in the context of a large-scale chemical incident. We propose a broadly consequentialist approach to on the spot ethical decision-making, but one which incorporates ethical values and rights as “side-constraints”. (shrink)

For the successful achievement of evidence-based practice, clinicians, managers and purchasers need evidence on whether a particular intervention works and ways to judge the appropriateness of the outcome criteria and measures used. Guidance is needed on what outcome measure to use, especially within routine clinical care settings. Beginning with a re-clarification of the difference between a health status and an outcome measure, the paper presents an evaluative checklist for use by clinical audit and research staff to review outcome measures for (...) use in routine care settings. Central features include the user-centredness of the measure, its psychometric properties, feasibility of use and utility. The applicability of the checklist is illustrated for outcome measurement in diabetes and stroke care. A modified form of the checklist is proposed for use by the busy clinician as an aid to the critical review of research papers within the context of evidence-based practice and to aid health care practitioners' choice of which outcome measure(s) to use within routine clinical care. (shrink)

There are quantum solutions for computational problems that make use of interference at some stage in the algorithm. These stages can be mapped into the physical setting of a single particle travelling through a many-armed interferometer. There has been recent foundational interest in theories beyond quantum theory. Here, we present a generalized formulation of computation in the context of a many-armed interferometer, and explore how theories can differ from quantum theory and still perform distributed calculations in this set-up. We shall (...) see that quaternionic quantum theory proves a suitable candidate, whereas box-world does not. We also find that a classical hidden variable model first presented by Spekkens : 32100, 2007) can also be used for this type of computation due to the epistemic restriction placed on the hidden variable. (shrink)