Ethical evaluation of deep brain stimulation as a treatment for Parkinson’s disease is complicated by results that can be described as involving changes in the patient’s identity. The risk of becoming another person following surgery is alarming for patients, caregivers and clinicians alike. It is one of the most urgent conceptual and ethical problems facing deep brain stimulation in Parkinson’s disease at this time. In our paper we take issue with this problem on two accounts. First, we elucidate what is (...) meant by “becoming another person” from a conceptual point of view. After critically discussing two broad approaches we concentrate on the notion of “individual identity” which centers on the idea of “core attitudes”. Subsequently we discuss several approaches to determine what distinguishes core attitudes from those that are more peripheral. We argue for a “foundational-function model” highlighting the importance of specific dependency relations between these attitudes. Our second aim is to comment on the possibility to empirically measure changes in individual identity and argue that many of the instruments now commonly used in selecting and monitoring DBS-patients are inappropriate for this purpose. Future research in this area is advised combining a conceptual and an empirical approach as a basis of sound ethical appraisal. (shrink)

ABSTRACTMany philosophers say that the nature of personal identity has to do with narratives: the stories we tell about ourselves. While different narrativists address different questions of personal identity, some propose narrativist accounts of personal identity over time. The paper argues that such accounts have troubling consequences about the beginning and end of our lives, lead to inconsistencies, and involve backwards causation. The problems can be solved, but only by modifying the accounts in ways that deprive them of their appeal.

It is widely held that every person is a person essentially, where being a person is having special mental properties such as intelligence and self-consciousness. It follows that nothing can acquire or lose these properties. The paper argues that this rules out all familiar psychological-continuity views of personal identity over time. It also faces grave difficulties in accounting for the mental powers of human beings who are not intelligent and self-conscious, such as foetuses and those with dementia.

Many philosophers working on personal identity and ethics say that personal identity is constituted by stories: narratives people tell or would tell about their lives. Most of them also say that this is personal identity in the ‘characterization sense’, that it is the notion people in ordinary contexts are interested in, and that it raises the ‘characterization question’. I argue that these claims are inconsistent. Narrativists can avoid the incompatibility in one of two ways: They can concede that their view (...) is not about the constitution but the epistemology of personal identity. Or they can say that it is not about personal identity at all. (shrink)

It has often been claimed that orthodox thinking about personal identity undermines the moral authority of advance directives in dementia by implying that the signer of the directive is numerically different from the severely demented patient. This is the ‘identity problem'. I introduce the problem, outline some well‐known solutions, and explain why they might be deemed unattractive. I then propose an alternative solution. It promises to be compatible with orthodox thinking about personal identity. I discuss three ways in which it (...) might be challenged and find that none is convincing. Personal identity is no bar to the moral authority of advance directives. (shrink)

Ein Leitmotiv der medizinethischen Auseinandersetzung mit der tiefen Hirnstimulation (THS) ist die Beschäftigung mit Fragen personaler Identität. Da es sich bei personaler Identität auch um ein Problem der theoretischen Philosophie handelt, wird in diesem Aufsatz nicht nur die praktische Frage nach der ethischen Legitimation der THS durch informierte Einwilligung gestellt und ein modifiziertes Legitimationskriterium für wesensändernde THS erarbeitet. Vielmehr wird zunächst versucht, das Problem, um das es in der Debatte um THS und personaler Identität geht, besser zu verstehen.

Ein Leitmotiv der medizinethischen Auseinandersetzung mit der tiefen Hirnstimulation (THS) ist die Beschäftigung mit Fragen personaler Identität. Da es sich bei personaler Identität auch um ein Problem der theoretischen Philosophie handelt, wird in diesem Aufsatz nicht nur die praktische Frage nach der ethischen Legitimation der THS durch informierte Einwilligung gestellt und ein modifiziertes Legitimationskriterium für wesensändernde THS erarbeitet. Vielmehr wird zunächst versucht, das Problem, um das es in der Debatte um THS und personaler Identität geht, besser zu verstehen.

Are physicians sometimes morally required to ease caregiver burden? In our paper we defend an affirmative answer to this question. First, we examine the well-established principle that medical care should be centered on the patient. We argue that although this principle seems to give physicians some leeway to lessen caregivers' suffering, it is very restrictive when spelled out precisely. Based on a critical analysis of existing cases for transcending patient-centeredness we then go on to argue that the medical ethos should (...) indeed contain a rule requiring physicians to alleviate caregiver burden under certain circumstances. Finally, we apply our findings to deep brain stimulation (DBS) for Parkinson's disease. We present empirical data from a recent study of DBS indicating that spousal caregivers of Parkinson patients treated with DBS are sometimes deeply troubled by the effects of the therapy and discuss what moral obligations the treating physicians may have in such cases. (shrink)

Ein Leitmotiv der medizinethischen Auseinandersetzung mit der tiefen Hirnstimulation (THS) ist die Beschäftigung mit Fragen personaler Identität. Da es sich bei personaler Identität auch um ein Problem der theoretischen Philosophie handelt, wird in diesem Aufsatz nicht nur die praktische Frage nach der ethischen Legitimation der THS durch informierte Einwilligung gestellt und ein modifiziertes Legitimationskriterium für wesensändernde THS erarbeitet. Vielmehr wird zunächst versucht, das Problem, um das es in der Debatte um THS und personaler Identität geht, besser zu verstehen.

Viele Menschen halten Patientenverfügungen für ein geeignetes Mittel, um selbstbestimmt zu entscheiden, wie mit ihnen im Fall schwerer Demenz umgegangen werden soll. Die meisten Bioethiker stimmen ihnen zu: Demenzverfügungen seien Ausdruck der „verlängerten Autonomie“ der Patientin. Doch ob sie recht haben, ist unklar. Dem viel beachteten Identitätseinwand zufolge sind die Ausstellerin der Verfügung und ihre schwer demente Nachfolgerin numerisch verschieden: Sie sind zwei und nicht eins. Wenn das stimmt, kann die Ausstellerin nicht verfügen, wie mit ihr im Falle schwerer Demenz (...) umgegangen werden soll. Die Demenzverfügung ist ungültig. In meinem Aufsatz möchte ich eine neue Replik auf diesen Einwand vorstellen. Ihr Ansatzpunkt ist der menschliche Organismus, den wir sehen, wenn wir in den Spiegel blicken. Er kann schwer dement werden, und auch er hat die Patientenverfügung unterschrieben. Warum sollte sie dann ungültig sein? Auf den ersten Blick hat diese Replik eine Reihe von Vorzügen. Insbesondere akzeptiert sie die populären Annahmen, auf denen der Identitätseinwand basiert. Bei näherem Hinsehen zeigen sich jedoch Probleme, die so gravierend sind, dass wir von ihr Abstand nehmen sollten. (shrink)

ObjectiveIn this study we used functional magnetic resonance imaging to investigate whether motor imagery of handwriting and circle drawing activates a similar handwriting network as writing and drawing itself.MethodsEighteen healthy right-handed participants wrote the German word “Wellen” and drew continuously circles in a sitting and lying position to capture kinematic handwriting parameters such as velocity, pressure and regularity of hand movements. Afterward, they performed the same tasks during fMRI in a MI and an executed condition.ResultsThe kinematic analysis revealed a general (...) correlation of handwriting parameters during sitting and lying except of pen pressure during drawing. Writing compared to imagined writing was accompanied by an increased activity of the ipsilateral cerebellum and the contralateral sensorimotor cortex. Executed compared to imagined drawing revealed elevated activity of a fronto–parieto-temporal network. By contrasting writing and drawing directly, executed writing induced an enhanced activation of the left somatosensory and premotor area. The comparison of the MI of these tasks revealed a higher involvement of occipital activation during imagined writing.ConclusionThe kinematic results pointed to a high comparability of writing in a vertical and horizontal position. Overall, we observed highly overlapping cortical activity except of a higher involvement of motor control areas during motor execution. The sparse difference between writing and drawing can be explained by highly automatized writing in healthy individuals. (shrink)

Aristotle's defense of Dunamis -- Power and potentiality -- Rational and nonrational powers -- The priority of actuality -- Ontological hierarchy, normativity, and gender.

I first examine the context that led me to write ‘The Root of all Evil.’ A second section rehearses my present understanding of the significance and the inadequacy of Heidegger’s fundamental ontology. A third section turns to the way my thinking has evolved, including a brief account of the way it has moved from Heidegger to the 15th century cardinal and philosopher Nicolaus Cusanus. I conclude with some remarks about what I take to be my place in today’s philosophy world.

The famous definition of landscape by Joachim Ritter unmistakably names the aesthetic act of construction that makes landscape vision possible: “Landscape is nature that is aesthetically present in the sight for a feeling and sensing observer”. Landscape is an aesthetic construct, in whose act of construction, however, social, cultural, individual and other constitutional factors flow. Following Karl Popper’s 3-world theory, a physical landscape (world 1), an individual landscape (world 2) and a social landscape (world 3) can be distinguished. In each (...) case, aesthetic and other constitutional factors are interconnected in a complex and complicated way. In addition, this situation is aggravated by the fact that different scientific basic positions (essentialism, positivism, constructivism) find their way into corresponding analyses (partly unreflected) and make scientific understanding difficult. Finally, this scientific starting position produces different paradigms, theories and terminology, which are often played off against each other and can lead to unfruitful dissent in science. The lecture counters this with a “neopragmatic” approach that can show that and how different paradigms, theories and conceptualisations can be related to each other in such a way that unfruitful dissent can be avoided and instead the advantages of the scientific plurality of theories, concepts and paradigms can be used and made fruitful for concrete research goals. (shrink)

This essay will defend a causal conception of action explanations in terms of an agent’s reasons by delineating a metaphysical and epistemic framework that allows us to view folk psychology as providing us with causal and autonomous explanatory strategies of accounting for individual agency. At the same time, I will calm philosophical concerns about the issue of causal deviance that have been at the center of the recent debates between causalist and noncausalist interpretations of action explanations. For that purpose, it (...) is important to realize that the domain of folk-psychological action explanation is also the domain of skillful and goal-directed bodily movements, a domain to which we have independent epistemic access. (shrink)

In this timely and wide-ranging study, Karsten Stueber argues that empathy is epistemically central for our folk-psychological understanding of other agents--that it is something we cannot do without in order to gain understanding of other minds. Setting his argument in the context of contemporary philosophy of mind and the interdisciplinary debate about the nature of our mindreading abilities, Stueber counters objections raised by some in the philosophy of social science and argues that it is time to rehabilitate the empathy (...) thesis.Empathy, regarded at the beginning of the twentieth century as the fundamental method of gaining knowledge of other minds, has suffered a century of philosophical neglect. Stueber addresses the plausible philosophical misgivings about empathy that have been responsible for its failure to gain widespread philosophical acceptance.Crucial in this context is his defense of the assumption, very much contested in contemporary philosophy of mind, that the notion of rational agency is at the core of folk psychology. Stueber then discusses the contemporary debate between simulation theorists--who defend various forms of the empathy thesis--and theory theorists. In distinguishing between basic and reenactive empathy, he provides a new interpretive framework for the investigation into our mindreading capacities. Finally, he considers epistemic objections to empathy raised by the philosophy of social science that have been insufficiently discussed in contemporary debates. Empathy theorists, Stueber writes, should be prepared to admit that, although empathy can be regarded as the central default mode for understanding other agents, there are certain limitations in its ability to make sense of other agents; and there are supplemental theoretical strategies available to overcome these limitations. (shrink)

The principles of responsible bioentrepreneurship are a call for multiple stakeholders to engage in a manifold discourse driving a solution-oriented innovation process.

Predicting the phenotype of an organism from its genotype is a central question in genetics. Most importantly, we would like to find out if the perturbation of a single gene may be the cause of a disease. However, our current ability to predict the phenotypic effects of perturbations of individual genes is limited. Network models of genes are one tool for tackling this problem. In a recent study, (Lee et al.) it has been shown that network models covering the majority (...) of genes of an organism can be used for accurately predicting phenotypic effects of gene perturbations in multicellular organisms. BioEssays 30:707–710, 2008. © 2008 Wiley Periodicals, Inc. (shrink)

The pre-1932 writings of Otto Kirchheimer are often described by researchers as the work of a young ‘left-Schmittian’, a radical Marxist who gave the anti-liberal critique and theoretical apparatus of his Doktorvater Carl Schmitt a new purpose for different ‘political ends’. The danger of this approach is that fundamental divisions between the societal conceptualizations of both theoreticians are ignored in lieu of apparent terminological similarity. Through the lens of economy, it is therefore the intent of this article to continue in (...) the tradition of Alfons Söllner and Frank Schale, pushing against this assumed affinity and highlighting Otto Kirchheimer’s unique defense of liberal democracy. (shrink)

The fearful ape hypothesis revolves around our ability to express and perceive fearfulness. Here, we address these abilities from a social learning perspective which casts fearfulness in a slightly different light. Our commentary argues that any theory that characterizes a (human) social signal as being adaptive, needs to address the role of social learning as an alternative candidate explanation.

This essay will defend a causal conception of action explanations in terms of an agent’s reasons by delineating a metaphysical and epistemic framework that allows us to view folk psychology as providing us with causal and autonomous explanatory strategies of accounting for individual agency. At the same time, I will calm philosophical concerns about the issue of causal deviance that have been at the center of the recent debates between causalist and noncausalist interpretations of action explanations. For that purpose, it (...) is important to realize that the domain of folk-psychological action explanation is also the domain of skillful and goal-directed bodily movements, a domain to which we have independent epistemic access. (shrink)

Der Tagungsband beinhaltet fünfzehn Beiträge einer interdisziplinären Tagung des wissenschaftlichen, bildungsorientierten und gemeinnützigen Arbeitskreises philosophierender Ingenieure und Naturwissenschaftler (APHIN) e.V. Der Band umfasst Aufsätze aus dem Spannungsfeld von Philosophie, Ingenieur- und Naturwissenschaften und Aufsätze, die diesen Bereich transzendieren. Alle Beiträge spiegeln die Neugierde und Freude wider, über den eigenen fachlichen Tellerrand hinauszuschauen. Und sie zeigen, dass der Philosophie hierbei eine Schlüsselrolle zukommt. Das Selbstverständnis von APHIN – die Offenheit für die Fragen und Probleme der jeweils anderen – ist damit in (...) allen Beiträgen gegenwärtig. (shrink)

Der demographische Wandel, die Veränderung von Akteurskonstellationen und Besitzverhältnissen, Suburbanisierungsprozesse, die Energiewende sowie neue private und öffentliche Nutzungsansprüche an Raum und Landschaft schaffen neue kulturelle, soziale, ökonomische, ökologische und politische Herausforderungen. Architektonische und planerische Disziplinen sind daher zur Zusammenarbeit aufgerufen, um die Herausforderungen der Zukunft bei der nachhaltigen Gestaltung, Nutzung und Schonung einer weiterhin bewohnbaren Welt annehmen, begleiten und mitsteuern zu können. Die Beiträge dieses Bandes gehen daher der Frage nach, ob und wie das wissenschaftstheoretische Konzept der Transdisziplinarität so genutzt (...) werden kann, dass die aspekthaften Ergebnisse der vielen Landschaftsforschungen und die ausserwissenschaftlichen Ansprüche lebensweltlicher Akteure wieder zusammengeführt und auf gemeinsame Forschungsperspektiven und Anwendungskontexte hin organisiert werden können. (shrink)

As shown through an inventory of the procedures used in diverse forms of qualitative content analysis projects, the logic of qualitative procedures is in most cases not standardized. Often researchers pay little or no attention to the procedures which they apply. This contribution presents and discusses a procedure for interpretive content analysis which was applied in an empirical study into trans-border news coverage in the Dutch-German Euregion Rhine-Waal. First, we will describe the study on the portrayal of the Dutch and (...) German people as well as their respective countries, The Netherlands and Germany, in the four main regional newspapers of this region. Secondly, basic principles of qualitative methodology are discussed and, thirdly, the procedure of the applied method based on these principles is presented and illustrated by means of exemplary material. Finally, after a brief presentation of some empirical results, the applied procedure of interpretive content analysis is discussed. (shrink)

This study explored in what way and to what extent people's occupational position corresponds with the consumption of news and the exposure to political content offered by the traditional mass media TV, radio, and newspaper, using survey data. The influence of occupational position in general and perceived amount of public social capital on especially consumption of news as well as the exposure to political media content, was evident. Findings are in line with the central assumptions on ‘audience activity’ of audience-centered (...) models in communication research in general and the ‘media use as social action’ approach especially. The subjectively perceived social context, indicated by occupational position as well as the subjectively held structure of relevancies is a central predictor of media use. (shrink)

Derek Parfit defends the Imprecise Lexical View as a way to avoid the Repugnant Conclusion. Allowing for ‘imprecise equality’, Parfit argues, makes it possible to avoid some well-known problems for the Lexical View. It is demonstrated that the Lexical View has stronger implications than envisaged by Parfit; moreover, his assumption of Non-diminishing Marginal Value makes the Lexical View collapse into a much stronger view, which lets the two appear incompatible. Introducing imprecise equality does not address the latter problem. But it (...) does makes it possible for the Imprecise Lexical View to soften the discontinuities it would otherwise face, at the cost of blurring the difference between options.However, if Non-diminishing Marginal Value is rejected, the remaining complications for the resulting most plausible version of the Imprecise Lexical View, including a confrontation with Arrhenius’ Non-Elitism Condition, may be within a range where the view largely remains defensible. (shrink)

Wissenschaftsfreiheit wird vorherrschend als Freiheit der Wissenschaft von politischer Einmischung verstanden. Der Artikel kritisiert dieses negative Verständnis von Wissenschaftsfreiheit anhand einer Analyse seines prominentesten Vertreters, dem Netzwerk Wissenschaftsfreiheit, das damit eine Politisierung einseitig den Vertreter*innen gesellschaftskritischer Ansätze zuschreibt, während es die eigene Position als ‚rein wissenschaftlich‘ und politisch neutral dargestellt. Demgegenüber schlägt der Artikel ein kritisches Verständnis von Wissenschaftsfreiheit vor, das seine Politizität reflektiert. Ausgehend von der Analyse, dass starre Macht- und Privilegienstrukturen das zentrale Hindernis für die gemeinsame Arbeit an (...) wissenschaftlicher Objektivität sind, geht es beim kritischen Begriff der Wissenschaftsfreiheit um die Reflexion und Transformation des Verhältnisses von Wissenschaft und Politik. Dabei steht die Diversifizierung von Zugangschancen und Standpunkten innerhalb der Wissenschaft im Mittelpunkt – also die Neuverteilung von Macht und Privilegien. Der Artikel entwickelt dieses Verständnis aus einer Diskussion des Verhältnisses von Wissenschaft und Politik in zwei philosophischen Begründungsmöglichkeiten der Wissenschaftsfreiheit und aus einer Rekonstruktion der kritischen politischen Theorie, insbesondere der foucaultschen Machttheorie und der feministischen Standpunkttheorie. Er zeigt auf dieser Grundlage, dass drei verschiedene Arten der Diversifizierung der Wissenschaft – intern, extern-institutionell und extern-aktivistisch –, die vom vor dem Hintergrund des negativen Begriffs als Einschränkung der Wissenschaftsfreiheit verstanden werden, tatsächlich zu ihrer Verbesserung beitragen. -/- . (shrink)

The content of a work of literature, Walter Benjamin reminds us in “The Author as Producer,” is inextricably bound up with its form. Hence, it is hardly astounding that much critical attention has been focused on the proper generic classification of Harriet E. Wilson’s Our Nig . This task, though, has not been easy. Henry Louis Gates, rediscoverer and earliest critic of Our Nig, for example, goes to great length discussing parallels between Wilson’s work and Nina Baym’s ‘overplot’ of the (...) ‘women’s novel,’ before settling on reading it as a new form of distinctly African-American lit- erature that combines “conventions of the sentimental novel with certain key conventions of the slave narratives” . Elizabeth Ammons, by contrast, places Our Nig squarely in the feminist tradition of the sentimental novel and argues that “the ideal of mother love explicit in Uncle Tom’s Cabin operates implicitly in Our Nig.” 4 2 3 Contesting Ammons’ claim, Eric Gardner asserts that Our Nig is not a ‘novel of abolition’ but “a novel about Northern racial issues, a young black woman’s bildungsroman, and, as such, is far from Uncle Tom’s Cabin.” 5 Echoing some of Gardner’s points, Elizabeth Breau contends that Our Nig “is actually satiric” and therefore gives an overly “bleak picture of northern antebellum society.” Foregrounding neither Bildung nor “ironic inversions” but the “politics of rage at work in Wilson’s tale,” Julia Stern argues that Our Nig “used the sentimental form to mask a gothic message.” 7 Rejecting Gates’ attempt to posit Our Nig as “a significant beginning of an African-American literary mode, a distinctive first in a century of firsts,” John Ernest wants to read Wilson’s work as a traditional “blend of autobiography and fiction,” hoping to ‘re-place’ it “within the racial, gender, and economic matrix of secular history.” R.J. Ellis, while accepting Gates’ assessment that Our Nig “draw[s] on the genres of sentimental fiction and abolitionist slave narrative,” stresses the ways in which the ‘hybrid’ work “fractures generic boundaries” in order to provide a “full retrieval of Frado’s pain, her experience of body politics.” Lastly, offering a reading that links Our Nig to the Puritan tradition, Elizabeth West argues that Our Nig “manipulates well-known trappings of the conversion narrative” by telling “the story of the heroine’s failed initiation into the community of earthly saints.”. (shrink)