Over the last decade the modeling and the storage of biological data has been a topic of wide interest for scientists dealing with biological and biomedical research. Currently most data is still stored in text files which leads to data redundancies and file chaos.In this paper we show how to use relational modeling techniques and relational database technology for modeling and storing biological sequence data, i.e. for data maintained in collections like EMBL or SWISS-PROT to better serve the needs for (...) these application domains.For this reason we propose a two step approach. First, we model the structure (and therefore the meaning of the) data using an Entity-Relationship approach. The ER model leads to a clean design of a relational database schema for storing and retrieving the DNA and protein data extracted from various sources. Our approach provides the clean basis for building complex biological applications that are more amenable to changes and software ports than their file-base counterparts. (shrink)

The paper is a critical comment on D. Hoffman. The Scrambling Theorem: A simple proof of the logical possibility of spectrum inversion. Consciousness and Cognition, 2006, 15, 31–45.

In 2016, following pandemic influenza threats and the 2014–2016 Ebola virus disease outbreaks, the WHO developed a guidance document for managing ethical issues in infectious disease outbreaks. In this article, we analyse some ethical issues that have had a predominant role in decision making in response to the current COVID-19 pandemic but were absent or not addressed in the same ways in the 2016 guidance document. A pandemic results in a health crisis and social and political crises both nationally and (...) globally. The ethical implications of these global effects should be properly identified so that appropriate actions can be taken globally and not just in national isolation. Our analysis, which is a starting point to test the broader relevance of the 2016 WHO document that remains the only available guidance document applicable globally, concludes that the WHO guidance should be updated to provide reasoned and thoughtful comprehensive ethics advice for the sound management of the current and future pandemics. (shrink)

Planning the first school transition for children with special needs focuses on several objectives: To ensure continuity amongst different children’s life settings; to ease the child’s adaptation and integration in their new environment; to support the school’s preparations in order to better welcome each child with their particularities; to adapt activities according to the child’s needs; and lastly, to encourage full participation of the parents and professionals who know the child. Qualitative-interpretative research allows us to examine the way stakeholders from (...) different sectors, including the parents, planned the transition to kindergarten of children with special needs. Three networks were studied over a period of one year. The results permit us to deepen our understanding of how stakeholders function together, as a network, in order to prepare a quality transition for the targeted children. The article presents a model of the structural and interactional processes involved during these planned transitions; these processes derive from the dynamic created by knowledge-sharing and networking between the stakeholders. The structural processes in turn benefit the stakeholders; specifically by providing opportunities for collective interactions and knowledge-sharing beyond their individual interests. In particular, the stakeholders accepted some shifts in changing roles as they moved from individualistic to collective action. Finally, the time dedicated by the stakeholders, along with the duration of the process, are determined to be key elements contributing to the quality of the entire experience. (shrink)

As systems based on opaque Artificial Intelligence (AI) continue to flourish in diverse real-world applications, understanding these black box models has become paramount. In response, Explainable AI (XAI) has emerged as a field of research with practical and ethical benefits across various domains. This paper not only highlights the advancements in XAI and its application in real-world scenarios but also addresses the ongoing challenges within XAI, emphasizing the need for broader perspectives and collaborative efforts. We bring together experts from diverse (...) fields to identify open problems, striving to synchronize research agendas and accelerate XAI in practical applications. By fostering collaborative discussion and interdisciplinary cooperation, we aim to propel XAI forward, contributing to its continued success. Our goal is to put forward a comprehensive proposal for advancing XAI. To achieve this goal, we present a manifesto of 27 open problems categorized into nine categories. These challenges encapsulate the complexities and nuances of XAI and offer a road map for future research. For each problem, we provide promising research directions in the hope of harnessing the collective intelligence of interested stakeholders. (shrink)

We conducted a rapid review and quantitative summary of meta-analyses that have examined interventions which can be used by individuals during quarantine and social distancing to manage anxiety, depression, stress and subjective well-being. A literature search yielded 34 meta-analyses (total number of studies k = 1,390, n = 145,744) that were summarized. Overall, self-guided interventions showed small to medium effects in comparison to control groups. In particular, self-guided therapeutic approaches (including cognitive-behavioral, mindfulness, and acceptance-based interventions), selected positive psychology interventions, and (...) multi-component and activity-based interventions (music, physical exercise) showed promising evidence for effectiveness. Overall, self-guided interventions on average did not show the same degree of effectiveness as traditional guided individual or group therapies. There was no consistent evidence of dose effects, baseline differences and differential effectiveness of eHealth interventions. More research on the effectiveness of interventions in diverse cultural settings is needed. (shrink)

Taken as a philosophical issue, the idea of representation implies the prior assumption of a difference between reality and its “doubles.” Things are paired with images, concepts, or symbols, acts with rules and norms, events with structures. Traditionally, the problem with representations has been their “accuracy,” the degree of fit between reality and its reproductions in the mind. When philosophers lost the hope of ever determining accuracy , they found consolation in the test of usefulness: a good representation is one (...) that works. The proof of its working is that it enables us to act on the world together.1 In such a frame, science, including anthropology, is conceived as the pursuit of privileged representations, privileged in that, by their nature of by their combination, they establish knowledge of a special kind. In the case of anthropology, “culture” has served as a sort of umbrella concept for representations. The strcuturalists have been most explicit about the need to think of representation in the plural, but their position is shared, in varying degrees, by all those who conceive of knowledge as the selection and combination of signs in systems, patterns, or structures, in short, as some kind of conceptual order ruling perceptual chaos. 1. Remember the connection between the Kantian quest for synthetic forms and Émile Durkheim’s idea of collective representations sustained by the moral authority of a society. Durkheim certainly was one to look for the “ethic” in the “ethnic” primitive, and it makes me wonder whether Stephen A. Tyler’s characterization of postmodern ethnography as a return to “an earlier and more powerful notion of the ethical character of all discourse, as captured in the ancient significance of the family of terms ‘ethos,’ ‘ethnos,’ ‘ethics’” might not signal a return to the Durkheimian fold . Johannes Fabian is professor of cultural anthropology at the University of Amsterdam. His publications include Jamaa: A Charismatic Movement in Katanga , Time and the Other: How Anthropology Makes Its Object , and Language and Colonial Power: The Appropriation of Swahili in the Former Belgian Congo, 1880-1938 . Two books will appear in 1990: History from Below: The Vocabulary of Elisabethville by André Yav, a commented edition-translation of a colonial history written in Swahili by the colonized for the colonized, and Power and Performance, a study of conceptions of power through popular wisdom and theater in Shaba/Zaire. (shrink)

lniciado como un movimiento crítico de la modernidad, el Sturm und Drang alemán propuso una concepción distinta del humano, que exigía una renovación de la razón en armonía con la totalidad de las facultades humanas en favor del desarrollo de la individualidad. De esta manera se centralizaba la cualidad creadora del ser humano, sin subordinar el desarrollo de las demás facultades humanas. En este trabajo se analiza la reinterpretación del mito de Prometeo en el trabajo de tres personalidades: el filósofo (...) Johann G. Herder, el literato Johann W. von Goethe y el compositor Ludwig van Beethoven. Del primero, se examina su teoría del genio, explicada por medio de la figura de Shakespeare; del segundo se aborda el lugar de Prometeo en la obra del poeta; mientras que del tercero se analiza su tercera sinfonía, Heroica. Al final, se concluye que, en lostres pensadores, la figura del titán Prometeo representa ese espíritu rebelde que, rechazando a los dioses, encamina todos sus actos hacia el engrandecimiento del ser humano y de la humanidad. (shrink)

Inhaltsverzeichnis/Table of Contents Themenschwerpunkt/Special Topic: Bolzano & Kant Gastherausgeber/Guest Editor: Sandra Lapointe Sandra Lapointe: Introduction Sandra Lapointe: Is Logic Formal? Bolzano, Kant and the Kantian Logicians Nicholas F. Stang: A Kantian Reply to Bolzano¿s Critique of Kant¿s Analytic-Synthetic Distinction Clinton Tolley: Bolzano and Kant on the Place of Subjectivity in a Wissenschaftslehre Timothy Rosenkoetter: Kant and Bolzano on the Singularity of Intuitions Waldemar Rohloff: From Ordinary Language to Definition in Kant and Bolzano Weitere Artikel/Further Articles Christian Damböck: Wilhelm Diltheys empirische (...) Philosophie und der rezente Methodenstreit in der analytischen Philosophie Bernd Prien: Socially Constituted Actions and Objects Daniel Enrique Kalpokas: Two Dogmas of Coherentism Jon Cogburn & Jeff W. Roland: Strong, therefore Sensitive. Misgivings about DeRose¿s Contextualism Andre Abath: Brewer¿s Switching Argument Essay-Wettbewerb/Essay Competition Amadeus Magrabi: The Value of Feelings for Decision-Making Stefan Reining: Do Pain-Accompanying Emotions Mislead Us?¿Considerations in the Light of Reactive Dissociation Phenomena Peter Königs: Patriotism. A Case Study in the Philosophy of Emotions Besprechungsaufsatz/Review Essay Christopher Gauker: What Do Your Senses Say? On Burge¿s Theory of Perception Diskussion/Discussion Georg Brun: Adequate Formalization and De Morgan¿s Argument Buchnotizen/Critical Notes. (shrink)

This article shows the contribution of German philosophy to the birth of psychiatry at the beginning of the 19th century. The physician and father of the term psychiatry (Psychiatrie), Johann Christian Reil, will evolve in his thinking. This evolution is due to the transition from a first stage, as a chemical reductionist, to a second stage, close to the philosophy of nature. The transition in his thinking occurs with Reil's change of philosophical orientation: from Kantian critical philosophy to Schelling's philosophy, (...) with the consequence that Reil proposes psychiatry as a discipline. (shrink)

During the 1980's and the early 1990's South Africa experienced disturbing political violence of an unprecedented scope, intensity and nature. It was disturbing because it entailed acts of horrifying brutality, notably the ‘necklace' and the massacre, all of this against the background of ‘civilized' and measured com promise and negotiation. It stubbornly continued despite the unbanning of the liberation political organisations, and the holding of ‘free and fair' elections in April 1994. And it was unprecedented in a whole range of (...) ways, but mainly because of the fact that it was intracommunal, or black- on- black, violence. It was the first time that Black political organisations had turned on each other rather than their white oppressors. For our purposes, what is interesting is the range of responses emanating from South African social scientists in explaining this new phenomenon. Historically, explaining Black political violence in South Africa has had a difficult time of it. Starting with Pierre van den Berghe in 1962, predictions of imminent revolution against the apartheid regime have been so regularly and frequently proved wrong, that a whole industry has arisen in explaining quiescence rather than violence. The first cluster of theories spawned by the 1976 schools uprising, as Frank Molteno noted in his 1979 review, were analytically disappointing, if not crudely racist. Subsequent overviews by Manganyi & du Toit in 1990, and Beinart in 1992 have born evidence of considerably greater sophistication.; Manganyi, N & A du Toit, ; Beinart, W ). Nevertheless, as I shall show, most have remained within quite conventional theoretical and structuralist parameters. Many have their roots in the earlier dominant Marxism of the 1970's. In this sense they tend towards structural and class determinism, towards absolutist notions of power, and absolutist moral judgement of both apartheid and the individuals associated, however indirectly, with it. In consequence, Black incumbents of apartheid structures were inevitably depicted as willess and powerless puppets dancing to the tune of omnipotent White masters. In this context, it was wrong to talk of black- on- black violence, since one side of this equation, in reality, represented white interests. Much of this analysis also started from quite easy notions of the origins of violence. In this view it was sufficient to show conflicts of interest, or contra diction, in order to conclude that violence had been adequately explained. Against this background the more hermeneutic contribution by André du Toit to the debate stands out as theoretically innovative, nuanced and bold. This is not to say that it is with out problems. But I do wish to present a picture of a social theorist of considerable imagination and subtletly. Looking back over these theories, it would be tempting to say that the first category of structuralist accounts, should be supplemented with the second category of hermeneutic, accounts. But simply adding theoretically discrepant accounts together is too easy. It is only when the whole notion of structure, employed in the first category, is rethought in post-structuralist form, that an integration of the two elements becomes feasible. This paper follows a Giddensian line in pursuing this reconceptualization. (shrink)

For several years now, early cinema historians have developed certain notions that can help us define, in a much broader context, the axes of research in intermedial studies. Even though I’ll be giving it a slightly different importance, the notion I will be borrowing from these historians here is that of the “parameter.” Work by André Gaudreault and Philippe Marion on the emergence of the cinematographic medium relies on the idea that the medium appears as the result of a choice (...) made by the historian. To write the history of any given medium and separate it into periods, one must also select the components “that gathered together as a way of giving ‘birth’ to that medium at.. (shrink)

Proceedings of the conference 'A Clearing _of_ the German Forest: Mysticism, Idealism and Romanticism', with contributions by Jens Halfwassen, Johann Kreuzer, Glenn A. Magee, Christian Danz, et al., concerning the relationship of Fichte, Hegel, Hölderlin and Schelling with the most important German mystics. Akten der Tagung 'Eine Lichtung _des_ deutschen Waldes: Mystik, Idealismus und Romantik', mit Beiträgen von Jens Halfwassen, Johann Kreuzer, Glenn A. Magee, Christian Danz, usw., das Verhältnis von Fichte, Hegel, Hölderlin und Schelling zu den zentralen Autoren der (...) deutschen Mystik betreffend. (shrink)

Johann Christoph Gottsched gehört unbestritten zu den zentralen Figuren der deutschen Frühaufklärung. Wie wohl kein anderer vor und nach ihm hat er die Entwicklung der deutschsprachigen Sprach-, Rede-, Dicht- und Bühnenkunst geprägt, geleitet von der festen Absicht, diesen Künsten wo möglich eine wissenschaftliche Begründung, eine überschaubare kritische Historie sowie eine klare und elegante Darstellung zu verleihen. Über diese Bemühungen hinaus, hat sich insbesondere die neuere Forschung weiteren Facetten seines riesigen Werkes zugewendet. So erscheint Gottsched als Vorbild zahlreicher Zeitschriftenprojekte, als wichtiger (...) Popularisator der Leibnizschen und Wolffschen Philosophie, als zentraler Reformer der zeitgenössischen Homiletik, als Drehscheibe bei der Vermittlung europäischer Dichtung und Gelehrsamkeit. Die Beiträge des vorliegenden Bandes tragen der gesamten Breite der Gottsched-Forschung Rechnung, prüfen alte Erkenntnisse und stellen neue Einschätzungen zur Diskussion. Darüber wird die Aufmerksamkeit auch auf weniger bekannte Aspekte des Gottschedschen Oeuvres gelenkt, so etwa auf Beiträge zu den Naturwissenschaften und der Staatslehre, auf die akademische Lehrtätigkeit und auf das zunehmende Interesse an anthropologischen und ästhetischen Fragen. MIT BEITRÄGEN VON: Erich Achermann, Thomas Althaus, Detlef Döring, Frank Grunert, Gerda Hassler, Peter Hesselmann, Hanspeter Marti, Christian Meierhofer, Dagmar Mirbach, Merio Scattola, Oliver Scholz, Tomas Sommadossi, Holger Steinmann, Gideon Stiening, Andres Strassberger, Dietmar Till, Klaus Weimar und Jan-Henrik Witthaus. (shrink)

In this article Johann David Michaelis’s views of language and translation are juxtaposed with his own experience as a translated and translating author, especially with regard to the translations of his prize essay on the reciprocal influence of language and opinions (1759). Its French version originated in a close collaboration with the translators, while the pirated English edition was anonymously translated at second hand. The article reconstructs Michaelis’s relationship with the French translators and his renouncement of the English version, publicly (...) condemned in London by Robert Lowth at the author’s request. These two processes represent different contemporary modes of translation and shed new light on emerging theories of linguistic and cultural transfer. (shrink)

In this article Johann David Michaelis’s views of language and translation are juxtaposed with his own experience as a translated and translating author, especially with regard to the translations of his prize essay on the reciprocal influence of language and opinions (1759). Its French version originated in a close collaboration with the translators, while the pirated English edition was anonymously translated at second hand. The article reconstructs Michaelis’s relationship with the French translators and his renouncement of the English version, publicly (...) condemned in London by Robert Lowth at the author’s request. These two processes represent different contemporary modes of translation and shed new light on emerging theories of linguistic and cultural transfer. (shrink)

We study notions of independence appropriate for a stability theory of metric abstract elementary classes (for short, MAECs). We build on previous notions used in the discrete case, and adapt definitions to the metric case. In particular, we study notions that behave well under superstability‐like assumptions. Also, under uniqueness of limit models, we study domination, orthogonality and parallelism of Galois types in MAECs.

In this editorial introduction, we set out the contexts, aims and contents of this special issue on Schelling’s influence on later religious and theological thought, as well as the rationale behind its genesis.

We study versions of limit models adapted to the context of metric abstract elementary classes. Under categoricity and superstability-like assumptions, we generalize some theorems from 7, 15-17. We prove criteria for existence and uniqueness of limit models in the metric context.

Large cardinals arising from the existence of arbitrarily long end elementary extension chains over models of set theory are studied here. In particular, we show that the large cardinals obtained in this fashion (`unfoldable cardinals') lie in the boundary of the propositions consistent with `V = L' and the existence of 0 ♯ . We also provide an `embedding characterisation' of the unfoldable cardinals and study their preservation and destruction by various forcing constructions.

Episodic memory has been analyzed in a number of different ways in both philosophy and psychology, and most controversy has centered on its self-referential,autonoeticcharacter. Here, we offer a comprehensive characterization of episodic memory in representational terms and propose a novel functional account on this basis. We argue that episodic memory should be understood as a distinctive epistemic attitude taken toward an event simulation. In this view, episodic memory has a metarepresentational format and should not be equated with beliefs about the (...) past. Instead, empirical findings suggest that the contents of human episodic memory are often constructed in the service of the explicit justification of such beliefs. Existing accounts of episodic memory function that have focused on explaining its constructive character through its role in future-oriented mental time travel do justice neither to its capacity to ground veridical beliefs about the past nor to its representational format. We provide an account of the metarepresentational structure of episodic memory in terms of its role in communicative interaction. The generative nature of recollection allows us to represent and communicate the reasons why we hold certain beliefs about the past. In this process, autonoesis corresponds to the capacity to determine when and how to assert epistemic authority in making claims about the past. A domain where such claims are indispensable are human social engagements. Such engagements commonly require the justification of entitlements and obligations, which is often possible only by explicit reference to specific past events. (shrink)

St. Thomas Aquinas has always considered intelligence a potency higher than the will, absolutely speaking. That being said, and in my view, the existential primacy of the will in the act of freedom (particularly in choosing the existential end) is also indisputably Thomistic, as Cornelio Fabro has shown. This paper endeavors to explain Aquinas' doctrine on the absolute primacy of the intellect and thus show that these two primacies can be affirmed coherently, that is, the intellect’s absolute primacy and the (...) will’s existential primacy. Firstly, I will explain the reasoning St. Thomas Aquinas uses in the Summa to justify the absolute primacy of the intellect over the will. Secondly, I will explore some parallel texts, in order to shed light on my interpretation of the Summa and expand our view regarding this and related doctrinal points. Thirdly, I will offer a brief study of Fabro’s position, one in which his concerns regarding the intellect’s absolute primacy are taken into account and carefully considered. (shrink)

El problema que se pretende resolver en este texto es el aporte del diálogo filosófico como unaaventura y experiencia que cura. El texto se justifica toda vez que ante una experiencia filosófica enla que las preguntas fundamentales parecen ser la fuente del quehacer filosófico, aparece el diálogocomo una excelente oportunidad de transformar la existencia y curar los males que aquejan alhombre postmoderno. El objetivo del texto se enmarca en la experiencia vital del filósofo quese ha dedicado toda su vida a (...) dar respuesta a inquietudes existenciales pero que en los actualesmomentos le apuesta al diálogo como la mejor manera de curar los males que nos aquejan. Laexperiencia curativa desde el filosofar transforma al ser humano y lo prepara para enfrentarlas grandes problemáticas de su quehacer cotidiano. La metodología utilizada fue de enfoquedescriptivo en la que las fuentes permitieron acercarse a la argumentación dialógica del filosofar.La experiencia íntima de la filosofía se da gracias al diálogo filosófico que, más que método, es unaexperiencia que posibilita la relación conmigo mismo, con los otros y con las cosas a través de lapalabra, la razón y la sensación que surge en el devenir mismo del diálogo; esto es lo que lleva aentender el diálogo como una experiencia que cura y transforma. Por medio del diálogo filosófico,se logra un autoconocimiento que tiene el poder de curar, sanar, reparar y transformar a la personahumana, al “hombre de carne y hueso”. (shrink)

Yuk Hui refers to cosmotechnics as the deep interweaving of human action and technology as shaped by diverse moral universes. In this article, I pit two views of cosmotechnics against each other. I...

The article starts by observing a parallel between the identification of Christ's humanity and universal human nature, for which Harnack repudiates some church fathers, and David Strauss' claim, in his Life of Jesus, that the subject of the Incarnation must be all humanity. It is argued that this oppositional stance is indicative of fundamental philosophical and theological differences between the Tübingen School and the Ritschl School. Those differences, however, are then explained as emerging from what is ultimately a common project (...) of a radical form of historical theology. This project, it is argued, Ritschl took over from Baur while correcting it in crucial ways. Taken together, the two central theological schools of the 19th century thus illustrate the potential and the limits of christian theology within the historicist paradigm. (shrink)

This paper is an enquiry into the philosophical fault-line that leads from mechanicism to posthumanism. I focus on a central aspect of posthumanism: the erosion of the distinction between organism and machine, nature and art, and the biological and engineering sciences. I claim that this shift can be placed in the seventeenth century, in Descartes’s biology. The Cartesian fusion of the natural and technological opened the door to distinctly posthuman understandings of the living body, its relation to technological extensions, and (...) the possibility of its drastic alteration. Descartes’s mechanicism demanded a reconceptualization of bodily boundaries, organismic unity, natural finality, causation, and bio/technological instrumentality; all of which Descartes boldly theorized in terms of the wondrous technologies of his day. This radical proposal obscured the possibility of thinking the human as ontologically unique, or as having an ideal unity. This paper will examine the posthuman ramifications of these aspects of Descartes’s philosophy. (shrink)

If there is no inner model with ω many strong cardinals, then there is a set forcing extension of the universe with a projective well-ordering of the reals.

Since it implies a reduction in the quality and the quantity of the natural resources, environmental degradation is a present day problem that requires immediate solutions. This situation is driving firms to undertake an environmental transformation process with the purpose of reducing the negative externalities that come from their economic activities. Within this context, environmental marketing is an emerging business philosophy by which organizations can address sustainability issues. Moreover, environmental marketing and orientation are seen as valuable strategies to improve a (...) firm's competitiveness. However, the literature that has analyzed the link between environmental strategies and firms' results has been inconclusive and contradictory. In this study, we propose and test a model that analyses how the implementation of ecological issues within a firm's marketing strategy and orientation influences organizational results. Data were obtained through a survey sent to Spanish manufacturing firms. The results show that environmental marketing positively affects firms' operational and commercial performance and this improvement will influence their economic results. Moreover, environmental marketing is revealed as an excellent strategy to obtain competitive advantages in costs and in product differentiation. Thus, this study agrees with the researchers who affirm that environmental strategies positively affect firm's competitiveness while reducing environmental impact. (shrink)