We study the appearance of genetic information starting from a system where self-reproductive and enzymatic functions are supported by the same sort of molecules. In a first phase, the information must have arisen in the form of rate independent sequences as records of enzymatic functions. Although this stage must have played an important role in evolution, it will be shown how its evolutive capacities were blocked by the impossibility of appearance of geno/phenotype duality. Finally, a logical scheme is proposed for (...) a transition process toward a system with a code offering a simplification of the conditions required from the assumption of a maximum use of the double RNA capacity, both reproductive and enzymatic. (shrink)

Firstly we consider the new results about enzymatic capabilities in the RNA. In this framework we analyse the sequence-folding duality as a precursor of the genotype/phenotype duality. We discuss then which are the evolutive potentialities and limitations for a system with the absence and the presence of a nucleic acid to proteins translator code. We study the arise of the code in the living systems as a form of deep interlooking between the logic of the machinery and its hardware, discussing (...) some problems that abstract modelization of this process implies. Finaly we propose to redefine the informational vocabulary usually employed in Molecular Biology. (shrink)

En el trabajo reconstruimos la trayectoria seguida en España por los agentes económicos extranjeros a lo largo del período 1936-1959. El primer estudio fue de Muñoz, Roldán y Serrano en 1978. En nuestros días hay más aportaciones, pues el tema es crucial para cualquier país. Analizamos los problemas con los nuevos "arreglos" legales y el liderazgo final de los Estados Unidos. Los datos de EE.UU. muestran una buena evidencia y por tanto una muy buena prueba del gran impacto de la (...) inversión directa extranjera en España durante este periodo. Por otro lado, cuestionamos la percepción convencional sobre la escasez de inversión extranjera en el país entre 1936 y 1959. Eso fue debido a dos aspectos claves, uno la necesidad y por el otro lado, la red de inversiones antes de 1936 que lo hicieron posible. (shrink)

(1991). Life as emergence: The roots of a new paradigm in theoretical biology. World Futures: Vol. 32, Creative Evolution in Nature, Mind, and Society, pp. 133-149.

Firstly we consider the new results about enzymatic capabilities in the RNA. In this framework we analyse the sequence-folding duality as a precursor of the genotype/phenotype duality. We discuss then which are the evolutive potentialities and limitations for a system with the absence and the presence of a nucleic acid to proteins translator code. We study the arise of the code in the living systems as a form of deep interlooking between the logic of the machinery and its hardware, discussing (...) some problems that abstract modelization of this process implies. Finaly we propose to redefine the informational vocabulary usually employed in Molecular Biology. (shrink)

La entrevista al doctor Camilo Fernández Cozman se realizó el 19 de julio de 2021, a 9 días del 28 de julio, fecha en la que se conmemora la Independencia del Perú.

Our memories elicit, in us, both beliefs about what the external world was like in the past, and beliefs about what our own past experience of it was like in the past. What explains the power of memories to do that? I tackle this question by offering an account of the content of our memories. According to this account, our memories are ‘token-reflexives’, in that they represent their own causal origin. My main contention will be that our memories are able (...) to provide us with evidence for the two types of beliefs due to the self-referential nature of their content. First, I will put forward a series of thought-experiments intended to raise several intuitions about the veridicality of memories. Next, I will introduce the view that memories are token-reflexives, and I will motivate it by pointing out that the view accommodates the relevant intuitions. And, then, I will return to the two types of beliefs prompted by our memories, and argue that conceiving memories as token-reflexives allows us to explain why memory has the power to elicit the two types of beliefs in us. (shrink)

We show how the Full Bayesian Significance Test (FBST) can be used as a model selection criterion. The FBST was presented by Pereira and Stern as a coherent Bayesian significance test. Key Words: Bayesian test; Evidence; Global optimization; Information; Model selection; Numerical integration; Posterior density; Precise hypothesis; Regularization. AMS: 62A15; 62F15; 62H15.

Este libro ofrece una imprescindible riqueza de perspectivas sobre el aspecto más problemático -que coincide con el menos tratado por los investigadores. de la obra de F. Nietzsche (1844-1990): la cuestión política. Nuestro reto de cara al Centenario de su muerte fue encarar lo que suele escamotearse. Y, al menos en este país, así ha sido por regla general. bien porque Nietzsche era "apolítico", otra forma más, como en el caso de otros pensadores, de situarlo universitariamente a la derecha, ángulo (...) desde el que se le importaba, ya porque, consigna progresista y transición filosófica, había que poner esta última interpretación en su sitio y demostrarle al mundo que Nietzsche había sido "utilizado erróneamente" por el totalitarismo nazi, el caso es que ya porque nos repugnaba moralmente aquella lectura, ya porque de tanto estar en favor de Nietzsche tampoco lo leíamos, cuestiones fundamentales de su obra y, por qué no decirlo, irritantes tanto para la derecho como para la izquierda, quedaron piadosamente salvadas. Y ahora ¿qué?... Los trabajos aquí presentados, nacionales e internacionales, han sido rigurosamente seleccionados. (shrink)

En este trabajo se analiza la tesis foucaultiana de la reducción de la filosofía a forma de conocimiento en Descartes y el consecuente abandono de la espiritualidad clásica, es decir, de la filosofía concebida como forma de vida basada en el cuidado de sí. A partir de aquí, además de observar que el propio Foucault matizará esta tesis, se demostrará que en Descartes la filosofía sigue esencialmente unida a la espiritualidad.

Se analizará una aporía inherente al giro subjetivo del último Foucault causada por el sostenimiento simultáneo de dos sentidos incompatibles de la irreductibilidad del sujeto y, por lo tanto, de su posible emancipación: en unos casos es posible hacer referencia a procesos de subjetivación externos a las formas de subjetividad generadas por el poder ; pero, en otros, los procesos de emancipación no pueden ser pensados más allá de la resistencia al poder. La hipótesis del trabajo es que la aporía (...) está producida por la gradual marginación del problema del autoconocimiento en la temática del cuidado de sí, que, como resultado, pasa a ser comprendida exclusivamente desde las prácticas cínicas. Pero reducido el autoconocimiento, también es eliminada la problemática del cuidado de sí, que sostenía la noción fuerte de la subjetividad. Se mostrará que en el Barroco literario y neoestoico español se pueden encontrar elementos para recuperarla. (shrink)

This paper explores the ethical dilemma of conflicting loyalties found in whistleblowing. Central to this dilemma is the internal/external disclosure dichotomy; disclosure of organisational wrongdoing to an external recipient is seen as disloyal, whilst disclosure to an internal recipient is seen as loyal. Understanding how the organisation and society have dealt with these problems over the last 30 years is undertaken through an analysis of Vandekerckhove’s project, which seeks to place the normative legitimisations of whistleblowing legislation and organisational whistleblowing policies (...) within a globalisation semantic able to contain this conflict between society and the organisation. This project fails, it is argued, because of Vandekerckhove’s particular understanding of the organisation as an autopoietic system, i.e. an operationally closed system. A case is made to understand organisations as complex systems, i.e. operationally open systems. Critical Complexity theory sees the identities of systems and components as coterminous. In the context of the organisation, this means that the identities of the corporation and its corporate members arise and die together. The whistleblower’s disclosure reconfigures the organisation by forcing the organisation to open up and make its boundaries flexible, making the designation ‘internal’ or ‘external’ to the organisation, and, therefore, who qualifies as a recipient of a disclosure of wrongdoing, flexible. The organisation is restrained from retailing against the whistleblower, because its identities are coterminous. Furthermore, as the disclosure cannot be categorically defined as either internal or external, the question of whether an external disclosure can qualify as an act of organisational loyalty becomes moot. (shrink)

Self-injury is a perilous and increasingly common behavior that is particularly prevalent among youth. Nonetheless, there is a deep-rooted public stigma towards people who self-injure. Consequently, people who engage in self-injury are reluctant to seek professional help or disclose their experiences to others. This article aims to combat stigma and promote help-seeking behavior by debunking the common myths surrounding self-injury in the Malaysian context. Specifically, this article aims to serve as an eye-opener for Malaysian counselors and other mental health professionals (...) to improve their multicultural knowledge, skills, and attitudes when working with those who self-injure. (shrink)

O presente estudo busca examinar alguns dos debates socrático-platônicos sobre a opinião pública diante da busca da verdade, e seu impacto político, particularmente para a democracia, que depende da noção de liberdade. Depois de se entender o avanço da visão de Platão sobre o problema da opinião e a impossibilidade de seu sobrepujamento geral, discute-se a visão do autor sobre o regime que dá poder ao demos e, ao final, que tipo de aprendizado se pode daí extrair para as democracias (...) contemporâneas. (shrink)

The main aim of this paper is to introduce an approach for understanding social cognition that we call the normative approach to social cognition. Such an approach, which results from a systematization of previous arguments and ideas from authors such as Ryle, Dewey, or Wittgenstein, is an alternative to the classic model and the direct social perception model. In section 2, we evaluate the virtues and flaws of these two models. In section 3, we introduce the normative approach, according to (...) which human, socio-cognitive competences rely on a myriad of social norms and routines that mediate our social interactions in such a way that we can make sense of each other without taking into consideration their mental states. In sections 4 and 5, we find some common premises shared by the two prior models and offer some arguments against them. In section 6, we advance some possible arguments against our approach and offer some responses against them. (shrink)

Recently, several scholars have argued in support of the idea that folk psychology involves a primary capacity for regulating our mental states and patterns of behavior in accordance with a bunch of shared social norms and routines :259–281, 2015; Zawidzki, Philosophical Explorations 11:193–210, 2008; Zawidzki, Mindshaping: A new framework for understanding human social cognition, MIT Press, Cambridge, 2013). This regulative view shares with the classical Dennettian intentional stance its emphasis on the normative character of human socio-cognitive capacities. Given those similarities, (...) it makes sense to assess the regulative view by considering some of the classical arguments against the normative nature of the intentional stance :76–100, 1985; Stich, Philosophical Topics 12:39–62, 1981; Stich, The fragmentation of reason: Preface to a pragmatic theory of cognitive evaluation, MIT Press, Cambridge, 1990). The aim of this paper is to argue that the priority that the regulative view lays on the pluralistic and regulative character of folk psychology leaves the theory well-placed to resist these arguments. In this sense, the regulative view possesses better theoretical options to defend the normative character of human social cognition. (shrink)

The texts of the Bible treasure a high amount of theatrical potential. Thus, the book of Job constituted the basis of the Theatrum Mundi . Nevertheless, the Jewish and Christian conception of the world and history, despite its tragedies and Passions, is far removed from Greek tragedy. The figure of Job constitutes a contrast to the tragic in King Lear . An exorcistic formula from the Bible appears in Hamlet, Macbeth, and in plays of the Faustian theme –El mágico prodigioso (...) and Marlowe’s and Goethe’s Fausts –, as well as, surprisingly, in Don Quixote and in many other plays where the devil appears on stage. OscarWilde’s Salome finds inspiration in the language of Song of Songs and of apocalyptic prophecies. Rituality and sacredness are common to the Bible and theatre in the quest for representation of the invisible through the visible. (shrink)