Cancers rely on multiple, heterogeneous processes at different scales, pertaining to many biomedical fields. Therefore, understanding cancer is necessarily an interdisciplinary task that requires placing specialised experimental and clinical research into a broader conceptual, theoretical, and methodological framework. Without such a framework, oncology will collect piecemeal results, with scant dialogue between the different scientific communities studying cancer. We argue that one important way forward in service of a more successful dialogue is through greater integration of applied sciences (experimental and clinical) (...) with conceptual and theoretical approaches, informed by philosophical methods. By way of illustration, we explore six central themes: (i) the role of mutations in cancer; (ii) the clonal evolution of cancer cells; (iii) the relationship between cancer and multicellularity; (iv) the tumour microenvironment; (v) the immune system; and (vi) stem cells. In each case, we examine open questions in the scientific literature through a philosophical methodology and show the benefit of such a synergy for the scientific and medical understanding of cancer. (shrink)

The objective of this article is to contribute to the epistemological, theoretical, methodological, and pedagogical debates concerning the relationship between research activities, training activities, and work activities. Its main focus is on new forms of engineering, thought of as cooperative and transformative. After situating the issues of the reciprocal triadic relationships between the three poles, the article presents two practical cases of transformative cooperative engineering. The authors then return to their epistemological position, which is socio-constructivist, complex, interactionist, and critical. They (...) sketch out the first elements of an elaborate system of intelligibility (multi-referential and transdisciplinary) aimed at supporting the hypothesis of an engineering process of joint transformation (trades, actors, organizations, training provision). The article also presents the research methodology (training-action-research) developed. A discussion of the issues and conditions of possibility of cooperative and transformative engineering concludes the article. (shrink)

This research aims to analyze the professionalization process of Master students in an adult education program, based in the University of Rennes (Brittany). The material uses ten reflexive analysis papers, produced by the students for each end of their year session (Master 1 and Master 2). This reflexive production, which aims to formalize and clarify the articulation of theoretical and praxeological aspects of the Master program, shows the integrative experience acquired during the year. The analysis of these papers allows us (...) to characterize the process of professional development from a model articulating three dimensions : 1) the identity dynamics linked with the process of professionalization, 2) the progressive professional socialization required by this professionalization, 3) the development of a specific posture, as a reflexive practitioner. The methodology employs a content analysis through inter-rater method. The results of this research offer a discussion on theoretical and practical levels, both for a better comprehension of professional development and for the trainers or program managers, to support this process of professionalization. (shrink)

Angiogenesis is a complex morphogenetic process regulated by growth factors, but also by the force balance between endothelial cells traction stresses and extracellular matrix viscoelastic resistance. Studies conducted with in vitro angiogenesis assays demonstrated that decreasing ECM stiffness triggers an angiogenic switch that promotes organization of EC into tubular cords or pseudo-capillaries. Thus, mechano-sensitivity of EC with regard to proteases secretion, and notably matrix metalloproteinases, should likely play a pivotal role in this switching mechanism. While most studies analysing strain regulation (...) of MMPs used cell cultured on stretched membranes, this work focuses on MMP expression during self-assembly of EC into capillary-like structures within fibrin gels, i.e. on conditions that mimics more closely the in vivo cellular mechanical microenvironment. The activity of MMP-2 and MMP-9, two MMPs that have a pivotal role in capillaries formation, has been monitored in pace with the progressive elongation of EAhy926 cells that takes place during the emergence of cellular cords. We found an increase of the zymogen proMMP-2 that correlates with the initial stages of EC cords formation. However, MMP-2 was not detected. ProMMP-9 secretion decreased, with levels of MMP-9 kept at a rather low value. In order to analyse more precisely the observed differences of EAhy926 response on fibrin and plastic substrates, we proposed a theoretical model of the mechano-regulation of proMMP-2 activation in the presence of type 2 tissue inhibitor of MMPs. Using association/dissociation rates experimentally reported for this enzymatic network, the model adequately describes the synergism of proMMP-2 and TIMP-2 strain activation during pseudo-capillary morphogenesis. All together, these results provide a first step toward a systems biology approach of angiogenesis mechano-regulation by cell-generated extracellular stresses and strains. (shrink)

This paper takes a novel approach to studying the existence and stability of Nash equilibria in N-firm Cournot–Bertrand oligopolies. First, we show that such games can be monotonically embedded into a game of strategic heterogeneity, so that each firm best responds to the choices of all other firms in a monotonic way. We then show that this monotonicity can be exploited to derive conditions which guarantee the existence of a unique, dominance solvable Nash equilibrium which is stable under all (...) adaptive dynamics. These conditions constitute a strict improvement over existing results in the literature. Finally, we examine the effect on these conditions resulting from additional firms entering the market. (shrink)

The main task for philosophers is introducing, clarifying, articulating, or simply redirecting concepts as—to echo Quine’s poetic formulation— “devices for working a manageable structure into the flux of experience.” I sometimes use “coining concepts” as shorthand for this task. When the concepts are quantitative they are part of a possible science ; when the concepts are qualitative they can be part of a possible philosophy. Of course, in practice, concepts are oft en stillborn, while others have multiple functions in fi (...) elds of inquiry that may straddle philosophy and science. In this chapter I argue that historians of philosophy must, among other things, coin concepts that disclose the near or distant past and create a shared horizon for our philosophical future. In virtue of our expertise we can often do so by drawing on previously orphaned concepts. The more narrow aim of this paper is to introduce two concepts, “Newton’s challenge to philosophy” and, especially, “philosophic prophecy,” that are suitable to philosophers who engage with texts in a scholarly fashion. I do so by re-telling the story of early analytical philosophy and its connection to the reception of Spinoza. By “Newton’s challenge to philosophy,” I mean the following: from about 1700 onward, “natural science” is increasingly taken to be authoritative in settling debates within philosophy; it is a concept that focuses attention on the authority of science and its various manifestations within philosophy. By “philosophic prophecy,” I mean the structured ways in which concept formation by philosophers can shape possible futures, including that of philosophy. In what follows, I first develop and characterize philosophic prophecy more precisely. In order to illuminate the concept, I contrast it with several related, more familiar concepts. Second, I offer brief critical comments on two alternative approaches to the history of philosophy promoted by Quentin Skinner and Michael Kremer in order to make more precise the approach favored here. Third, I offer a fresh narrative about the prehistory and origin of analytical philosophy. My story focuses on Ernest Nagel, who, I claim, is the philosophic prophet of analytical philosophy. Along the way, I explore the shared origins of analytical philosophy and analytical history of philosophy in the anti-Spinozistic writings of George Boole and Bertrand Russell. I oppose Nagel’s and Russell’s narratives in light of Moritz Schlick, the founder of the Vienna Circle. I adopt Schlick’s bold and unappreciated vision of the task of philosophy in scientific age. I focus on his identification of philosophical legislation with qualitative concepts. (shrink)

Philosopher and comedy writer (Futurama, Big Bang Theory) Kaplan tackles a metaphysical paradox: there are some things we dearly believe in that are not universally acknowledged as real. Here, Kaplan shows how philosophy giants Bertrand Russell and Ludwig Wittgenstein strove to smooth over this uncomfortable meeting of the real and unreal--and failed. From there he turns to mysticism's attempts to resolve such paradoxes, surveying Buddhism, Taoism, early Christianity, Theosophy, and even the philosophers at UC Berkeley under whom he studied. (...) Finally, he alights on--surprise--comedy as the ultimate resolution of the fundamental paradoxes of life. Ultimately, Kaplan delves deeper into the implications of this deceptively simple revelation, from how our physical brains work to his own personal confrontations with life's biggest questions: If we're all going to die, what's the point of anything? What is a perfect moment? What can you say about God? Or Santa? The answers in this book will cheer the rest of your life.--Adapted from publisher description. (shrink)

Based on the foundation of Wittgenstein's Tractatus and related writings of Bertrand Russell, Truth and Knowledge explores the basic problems of knowledge through the process of developing a theory of truth, uniquely the author's own.

"In this introduction I use Bertrand Russell's (1945) The History of Western Philosophy (hereafter: History), to introduce the meta-philosophical themes that recur throughout the chapters of this book. In particular, I focus on the way the distinction or opposition between rustic thought, which is supposed to characterize barbarous societies, and the urbane thought that is purported to characterize civilized society can help explain some entrenched patterns of exclusion visible in contemporary philosophy. I embed these remarks in a larger, speculative (...) historiography of the very idea of 'western philosophy.' Along the way, I provide an overview of the chapters of this volume"--. (shrink)

In this introduction I use Bertrand Russell's (1945) The History of Western Philosophy (hereafter: History), to introduce the meta-philosophical themes that recur throughout the chapters of this book. In particular, I focus on the way the distinction or opposition between rustic thought, which is supposed to characterize barbarous societies, and the urbane thought that is purported to characterize civilized society can help explain some entrenched patterns of exclusion visible in contemporary philosophy. I embed these remarks in a larger, speculative (...) historiography of the very idea of 'western philosophy.' Along the way, I provide an overview of the chapters of this volume. (shrink)

Christopher Pincock analyses the evolution of the Russellian theory of induction and compares it to Reichenbach's.

Fruit du colloque organisé en 2006 par les universités de Liège, de Saint-Louis de Bruxelles et Charles-de-Gaulle Lille 3, ce livre se présente sous la forme d’un imposant volume qui présente de nombreuses biographies. L’ouvrage est divisé en cinq parties, très déséquilibrées : la part du lion, réservée au politique, comprend dix contributions, mais celle qui traite des reines n’en comprend que deux et semble ignorer les très nombreux travaux de l’historiographie anglo-saxonne sur le queenshi...

El autor intenta mostrar que el concepto de ley es totalmente innecesario y que solo sirve para crear confusiones y generar falacias. Para ello muestra que la supuesta “ley de la causalidad” es inconsistente y que la ciencia no requiere de ella más que en una primera fase. Las ciencias maduras usan relaciones, en concreto, relaciones mediante ecuaciones diferenciales para desempe\ nar el papel que se le quiere otorgar a la ley de la causalidad. Despues de hacer esto, el autor (...) presenta varias confusiones relacionadas con el concepto de causa, y su solución si se asume lo anteriormente dicho. (shrink)

ABSTRACT Through a brief analysis of the reflections of some prestigious contemporary philosophers such as Norberto Bobbio, Mulford Quickert Sibley, Wilhelm Emil Mühlmann, Michael Allen Fox, David Cortright, Larry May, John Rawls, Eric Reitan, Johan Galtung and David Boersema, this essay reconstructs Russell's pacifist commitment during the First World War. This dramatic event represented a real watershed for his multifaceted and ingenious personality, leading to his new political and civil commitment. Through a series of articles and lectures, he fought against (...) militarism, was in favour of a world government and underlined the psychological causes of war. All this coincided in part with the outbreak of the Russian Revolution, the ideas of which he initially shared; at the time of the Leeds Convention, he believed that the March revolution would involve a complete political and economic change at the international level by removing the causes of war. It was not by chance that he decided to join the Independent Labour Party, a choice that marked his separation from the Liberals. Although the latter explored in depth different forms of pacifism, Russell implicitly recalled the formula ‘Pax enim non belli privatio’ by Baruch Spinoza, supporting a fundamental paradigm of the modern political theory. (shrink)

Immensely intelligible, thought-provoking guide by Nobel prize-winner considers such topics as the distinction between appearance and reality, the existence and nature of matter, idealism, inductive logic, intuitive knowledge, many other subjects. For students and general readers, there is no finer introduction to philosophy than this informative, affordable and highly readable edition that is "concise, free from technical terms, and perfectly clear to the general reader with no prior knowledge of the subject."—The Booklist of the American Library Association.

Bertrand Russell was one of the greatest logicians since Aristotle, and one of the most important philosophers of the past two hundred years. As we approach the 125th anniversary of the Nobel laureate's birth, his works continue to spark debate, resounding with unmatched timeliness and power. The Problems of Philosophy, one of the most popular works in Russell's prolific collection of writings, has become core reading in philosophy. Clear and accessible, this little book is an intelligible and stimulating guide (...) to those problems of philosophy which often mistakenly lead to its status as too lofty and abstruse for the lay mind. Focusing on problems he believes will provoke positive and constructive discussion, Russell concentrates on knowledge rather than metaphysics, steering the reader through his famous 1910 distinction between "knowledge by acquaintance and knowledge by description," and introducing important theories of Descartes, Kant, Hegel, Hume, Locke, Plato, and others to lay the foundation for philosophical inquiry by general readers and scholars alike.With a new introduction by John Perry, this valuable work is a perfect introduction to the field and will continue to stimulate philosophical discussion as it has done for nearly forty years. (shrink)

Ten brilliant essays on logic appear in this collection, the work of one of the world’s best-known authorities on logic. In these thought-provoking arguments and meditations, Nobel Prize winner Bertrand Russell challenges the romantic mysticism of the 19th century, positing instead his theory of logical atomism. These essays are categorized by Russell as "entirely popular" and "somewhat more technical." The former include the well-known title essay plus "A Free Man’s Worship" and "The Place of Science in a Liberal Education"; (...) the latter comprise "On the Notion of Cause" and "Knowledge by Acquaintance and Knowledge by Description," along with other essays written in the cogent and witty style for which their author is justly renowned. (shrink)

This brilliant and controversial work investigates the relationship between 'individual' and 'scientific' knowledge.

The Problems of Philosophy is a 1912 book by Bertrand Russell, in which Russell attempts to create a brief and accessible guide to the problems of philosophy. Focusing on problems he believes will provoke positive and constructive discussion, Russell concentrates on knowledge rather than metaphysics: If it is uncertain that external objects exist, how can we then have knowledge of them but by probability. There is no reason to doubt the existence of external objects simply because of sense data. (...) Russell guides the reader through his famous 1910 distinction between knowledge by acquaintance and knowledge by description and introduces important theories of Plato, Aristotle, René Descartes, David Hume, John Locke, Immanuel Kant, Georg Wilhelm Friedrich Hegel and others to lay the foundation for philosophical inquiry by general readers and scholars alike. "In the following pages I have confined myself in the main to those problems of philosophy in regard to which I thought it possible to say something positive and constructive, since merely negative criticism seemed out of place. For this reason, theory of knowledge occupies a larger space than metaphysics in the present volume, and some topics much discussed by philosophers are treated very briefly, if at all. (shrink)

Abstractabstract:This article examines Harold Ramis’s 2005 noir comedy The Ice Harvest as the critically dystopian counter-panel to his beloved 1993 film Groundhog Day, a film frequently discussed within the paradigm of utopia. While starkly different in genre, tone, and reception, the two films comprise a dialectical dyad that registers the historical transition from the utopian cultural effervescence of the early 1990s to the tragic foreclosure of imaginative horizons and the dystopian transformation of economic, political, and social landscapes in the new (...) millennium. In The Ice Harvest, the author argues, this is achieved through a strategic reactivation of film noir as a variant of the critical dystopia. (shrink)

Un livre pour défaire le régime esthétique de l'image, en vue d'une nouvelle pensée diagrammatique, après Deleuze et Guattari, entre art et philosophie : un ouvrage introductif et spéculatif sans équivalent qui, partant de la rupture opérée par Matisse et Duchamp avec la phénoménologie picturale de l'image esthétique, constitue une archéologie de l'art contemporain qui passe par Daniel Buren, Gordon Matta-Clark, Günter Brus et le néoconcrétisme brésilien.

For critical legal scholars, the ongoing far-right assault upon the liberal status quo poses a distinct dilemma. On the one hand, the desire to condemn the far-right is overwhelming. On the other hand, such condemnations are susceptible to being appropriated as a validation of the very liberalism that critical theorists have long questioned. In seeking to transcend this dilemma, my focus is on the discourse of ‘white genocide’ — a commonplace belief amongst the far-right/white nationalists that ‘whites’, as a discrete (...) group, are facing demographic destruction as a result of deliberate policy choices. Such a belief has motivated acts of extreme violence. While libel to dismissal by experts on mainstream understandings of genocide, namely international criminal lawyers, I argue that this ‘white genocide’ discourse deserves careful scrutiny as a jurisprudential and socio-legal phenomenon that reveals key weaknesses in present modalities of liberal justification. Drawing upon an array of recent critical theories, I show how a liberalism unable to face its own decline enables the very far-right assertions it purports to oppose. Thus, given liberalism’s failure to act as a neutral arbiter, an alternative approach for those opposing the far-right is to develop a vision of politics and society that confront believers in ‘white genocide’ on a more substantive level. This, I argue, forces the far-right’s opponents to disavow liberal scepticism towards utopian transformation as well as the juridical understandings and institutions that allow this scepticism to durably persist. (shrink)

Contrary to Vaesen's argument that humans are unique with respect to nine cognitive capacities essential for tool use, we suggest that although such cognitive processes contribute to variation in tool use, it does not follow that these capacities arenecessaryfor tool use, nor that tool use shaped cognition per se, given the available data in cognitive neuroscience and behavioral biology.

This anthology is a thorough introduction to classic literature for those who have not yet experienced these literary masterworks. For those who have known and loved these works in the past, this is an invitation to reunite with old friends in a fresh new format. From Shakespeare's finesse to Oscar Wilde's wit, this unique collection brings together works as diverse and influential as The Pilgrim's Progress and Othello. As an anthology that invites readers to immerse themselves in the masterpieces of (...) the literary giants, it is must-have addition to any library. (shrink)

Philosophy, from the earliest times, has made greater claims, and achieved fewer results, than any other branch of learning. In Our Knowledge of the External World , Bertrand Russell illustrates instances where the claims of philosophers have been excessive, and examines why their achievements have not been greater.

Here is a thoroughly updated edition of a classic in palliative medicine. Two new chapters have been added to the 1991 edition, along with a new preface summarizing where progress has been made and where it has not in the area of pain management. This book addresses the timely issue of doctor-patient relationships arguing that the patient, not the disease, should be the central focus of medicine. Included are a number of compelling patient narratives. Praise for the first edition "Well (...) written. . .should be read by everyone in medical practice or considering a career in medicine."---JAMA. "Memorable passages, important ideas, and critical analysis. This is a book that clinicians and educators should read."---New England Journal of Medicine. (shrink)

'These propositions may seem mild, yet, if accepted, they would absolutely revolutionize human life.' With these words Bertrand Russell introduces what is indeed a revolutionary book. Taking as his starting-point the irrationality of the world, he offers by contrast something 'wildly paradoxical and subversive' Sceptical Essays has never been out of print since its first publication in 1928. Today, besieged as we are by the numbing onslaught of twenty-first-century capitalism, Russell's defense of scepticism and independence of mind is as (...) timely as ever. In clear, engaging prose, he guides us through the key philosophical issues that affect our daily life. (shrink)

Preface -- Introduction -- How to value democracy -- Paper stones, the ethics of participation -- Philosophers-citizens -- Superdeliberators -- What is it like to be a citizen? -- Democracy's ethics of belief -- The division of democratic labor -- Representing principles -- Democratic complicity -- Not in my name, macrodemocratic design.

Philip Kitcher has proposed a theory of explanation based on the notion of unification. Despite the genuine interest and power of the theory, I argue here that the theory suffers from a fatal deficiency: It is intrinsically unable to account for the asymmetric structure of explanation, and thus ultimately falls prey to a problem similar to the one which beset Hempel's D-N model. I conclude that Kitcher is wrong to claim that one can settle the issue of an argument's explanatory (...) force merely on the basis of considerations about the unifying power of the argument pattern the argument instantiates. (shrink)

" Dr. Cassell discusses the world of the sick, the healing connection and healer's battle, the role of omnipotence in the healer's art, illness and disease, and ...

In recent years deflationary accounts of self-deception, under the banner of motivationalism, have proven popular. On these views the deception at work is simply a motivated bias. In contrast, we argue for an account of self-deception that involves more robustly deceptive unconscious processes. These processes are strategic, flexible, and demand some retention of the truth. We offer substantial empirical support for unconscious deceptive processes that run counter to certain philosophical and psychological claims that the unconscious is rigid, ballistic, and of (...) limited cognitive sophistication. (shrink)

In recent years, a hierarchical view of reality has become extremely influential. In order to understand the world as a whole, on this view, we need to understand the nature of the fundamental constituents of the world. We also need to understand the relations that build the world up from these fundamental constituents. Building pluralism is the view that there are at least two equally fundamental relations that together build the world. It has been widely, though tacitly, assumed in a (...) variety of important metaphysical debates. However, my primary aim in this paper is to argue that this has been a mistake. I will show that serious problems concerning the relationship between building and fundamentality afflict pluralism and are likely fatal to it. I claim that, for better or worse, our best hope is building singularism, the view that there is a single most fundamental building relation. I conclude by examining the advantage that singularist accounts enjoy over their pluralist rivals. (shrink)

An enduring question in the philosophy of science is the question of whether a scientific theory deserves more credit for its successful predictions than it does for accommodating data that was already known when the theory was developed. In The Paradox of Predictivism, Eric Barnes argues that the successful prediction of evidence testifies to the general credibility of the predictor in a way that evidence does not when the evidence is used in the process of endorsing the theory. He illustrates (...) his argument with an important episode from nineteenth-century chemistry, Mendeleev's Periodic Law and its successful predictions of the existence of various elements. The consequences of this account of predictivism for the realist/anti-realist debate are considerable, and strengthen the status of the 'no miracle' argument for scientific realism. Barnes's important and original contribution to the debate will interest a wide range of readers in philosophy of science. (shrink)

In What Is Thought? Eric Baum proposes a computational explanation of thought.

The Conquest of Happiness is Bertrand Russell’s recipe for good living. First published in 1930, it pre-dates the current obsession with self-help by decades. Leading the reader step by step through the causes of unhappiness and the personal choices, compromises and sacrifices that lead to the final, affirmative conclusion of ‘The Happy Man’, this is popular philosophy, or even self-help, as it should be written.

I analyzed 298 open-ended responses of undergraduate students who have been reported for cheating to the question, “What, if anything, would have stopped you from committing your act of academic dishonesty?” These responses included a few major themes: students pled ignorance of what constitutes academic dishonesty and the consequences/seriousness associated with violations; students tended to deflect blame, usually by saying that their professor could have done something differently ; students did not feel they had enough time, resources, and/or skills to (...) get the desired result without taking responsibility for this lack of time, resources, and/or skills ; students felt they did not manage their time well with accepting the blame for the poor time management; and that a bad grade was not an option. These data and results are discussed in relation to the extant literature on the topic. (shrink)

An enduring question in the philosophy of science is the question of whether a scientific theory deserves more credit for its successful predictions than it does for accommodating data that was already known when the theory was developed. In The Paradox of Predictivism, Eric Barnes argues that the successful prediction of evidence testifies to the general credibility of the predictor in a way that evidence does not when the evidence is used in the process of endorsing the theory. He illustrates (...) his argument with an important episode from nineteenth-century chemistry, Mendeleev's Periodic Law and its successful predictions of the existence of various elements. The consequences of this account of predictivism for the realist/anti-realist debate are considerable, and strengthen the status of the 'no miracle' argument for scientific realism. Barnes's important and original contribution to the debate will interest a wide range of readers in philosophy of science. (shrink)

The impact of socially responsible corporate behavior on economic performance is a major preoccupation of managers today. This article explores the links between narrowly defined constructs: stakeholder orientation, environmental proactivity and profitability, from the perspectives of stakeholder theory and resource-based theory. We collected data on the food and beverage, and household and personal products industries. Using structural equation modeling, this paper makes two contributions. We found a negative link between companies simply having a higher stakeholder orientation and profitability. Importantly, however, (...) environmental proactivity not only had a positive impact on profitability, but also appeared to mediate the relationship between stakeholder orientation and profitability. In other words, if a company is more environmentally proactive, it will be more attentive to a broad array of stakeholders, and this will in turn contribute positively to profitability. (shrink)

Standard microbial evolutionary ontology is organized according to a nested hierarchy of entities at various levels of biological organization. It typically detects and defines these entities in relation to the most stable aspects of evolutionary processes, by identifying lineages evolving by a process of vertical inheritance from an ancestral entity. However, recent advances in microbiology indicate that such an ontology has important limitations. The various dynamics detected within microbiological systems reveal that a focus on the most stable entities (or features (...) of entities) over time inevitably underestimates the extent and nature of microbial diversity. These dynamics are not the outcome of the process of vertical descent alone. Other processes, often involving causal interactions between entities from distinct levels of biological organisation, or operating at different time scales, are responsible not only for the destabilisation of pre-existing entities, but also for the emergence and stabilisation of novel entities in the microbial world. In this article we consider microbial entities as more or less stabilised functional wholes, and sketch a network-based ontology that can represent a diverse set of processes including, for example, as well as phylogenetic relations, interactions that stabilise or destabilise the interacting entities, spatial relations, ecological connections, and genetic exchanges. We use this pluralistic framework for evaluating (i) the existing ontological assumptions in evolution (e.g. whether currently recognized entities are adequate for understanding the causes of change and stabilisation in the microbial world), and (ii) for identifying hidden ontological kinds, essentially invisible from within a more limited perspective. We propose to recognize additional classes of entities that provide new insights into the structure of the microbial world, namely “processually equivalent” entities, “processually versatile” entities, and “stabilized” entities. (shrink)

Standard animalists are committed to a stringent form of restricted composition, thereby denying the existence of brains, hands, and other proper parts of an organism . One reason for positing this near-nihilistic ontology comes from various challenges to animalism such as the Thinking Parts Argument, the Unity Argument, and the Argument from the Problem of the Many. In this paper, I show that these putatively distinct arguments are all instances of a more general problem, which I call the ‘Too Many (...) Candidates Problem’ . Given my formulation of the problem, it is evident that standard animalists are mistaken in believing that restricting composition is the only solution. I show that there is another option for solving the TMC. The advantage of such a position, which I call ‘unrestricted animalism’, is that it is compatible with unrestricted composition and the existence of brains and other proper parts of an organism. I conclude by sketching several strategies one can take regarding this latter solution to the TMC. (shrink)

How should we deal with mental disorder - as an "illness" like diabetes or bronchitis, as a "problem in living", or what? This book seeks to answer such questions by going to their roots, in philosophical questions about the nature of the human mind, the ways in which it can be understood, and about the nature and aims of scientific medicine. The controversy over the nature of mental disorder and the appropriateness of the "medical model" is not just an abstract (...) theoretical debate: it has a bearing on very practical issues of appropriate treatment, as well as on psychiatric ethics and law. A major contention of this book is that these questions are ultimately philosophical in character: they can be resolved only if we abandon some widespread philosophical assumptions about the "mind" and the "body", and about what it means for medicine to be "scientific". The "phenomenological" approach of the twentieth-century French philosopher, Maurice Merleau-Ponty is used to question these assumptions. His conception of human beings as "body-subjects" is argued to provide a more illuminating way of thinking about mental disorder and the ways in which it can be understood and treated. The conditions we conventionally call "mental disorders" are, it is argued, not a homogeneous group: the standard interpretation of the medical model fits some more readily than others. The core mental disorders, however, are best regarded as disturbed ways of being in the world, which cause unhappiness because of deviation from "human" rather than straightforwardly "biological" norms. That is, they are problems in how we experience the world and especially other people, rather than in physiological functioning - even though the nature of our experience cannot ultimately be separated from the ways in which our bodies function. This analysis is applied within the book both to issues in clinical treatment and to the special ethical and legal questions of psychiatry. Written by a well known philosopher in an accessible and clear style, this book should be of interest to a wide range of readers, from psychiatrists to social workers, lawyers, ethicists, philosophers and anyone with an interest in mental health. (shrink)

Some compatibilists have responded to the manipulation argument for incompatibilism by proposing an historical theory of moral responsibility which, according to one version, requires that agents be morally responsible for having their pro-attitudes if they are to be morally responsible for acting on them. This proposal, however, leads obviously to an infinite regress problem. I consider a proposal by Haji and Cuypers that addresses this problem and argue that it is unsatisfactory. I then go on to propose a new solution (...) inspired by the libertarian theory of Robert Kane. (shrink)