Results for 'Sara Franceschelli'

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  1. “Une théorie dynamique de la morphogenèse. Commentaires de Sara Franceschelli et Jean Petitot à “Une théorie dynamique de la morphogenèse””.Sara Franceschelli - 2019 - In René Thom. Oeuvres Mathématiques Complètes. Volume II. Société Mathématique de France. pp. 343-362.
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  2. “ « And the rod starts to swing ». Morphogènes, instabilités et organismes imaginaires dans l’approche de Turing à la biologie » ”.Sara Franceschelli - 2020 - Intellectica 72:191-214.
  3. Arguments of stability in the study of morphogenesis.Sara Franceschelli - 2017 - Azafea: Revista de Filosofia 19:117-135.
    Arguments of stability, intended in a wide sense, including the discussion of the conditions of the onset of instability and of stability changes, play a central role in the main theorizations of morphogenesis in 20th century theoretical biology. The aim of this essay is to shed light on concepts and images mobilized in the construction of arguments of stability in theorizing morphogenesis, since they are pivotal in establishing meaningful relationships between mathematical models and empirical morphologies.
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  4. Morphogenesis, Structural Stability, and the Epigenetic Landscape.Sara Franceschelli - 2011 - In P. Bourgine & A. Lesne (eds.), Morphogeneis. Springer.
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  5. Morphogenèse, stabilité structurelle et paysage épigénétique.Sara Franceschelli - 2006 - In Morphogenèse. L'origine des formes. Paris: Belin. pp. 298-308.
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  6. "Some remarks on the compatibility between determinism and unpredictability".Sara Franceschelli - 2012 - Progress in Biophysics and Molecular Biology 110 (1):61-68.
    Determinism and unpredictability are compatible since deterministic flows can produce, if sensitive to initial conditions, unpredictable behaviors. Within this perspective, the notion of scenario to chaos transition offers a new form of predictability for the behavior of sensitive to initial condition systems under the variation of a control parameter. In this paper I first shed light on the genesis of this notion, based on a dynamical systems approach and on considerations of structural stability. I then suggest a link to the (...)
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  7. Morphogenesis and Design. Thinking through Analogs.Sara Franceschelli - 2016 - In The Routledge Companion to Biology in Art and Architecture. New York: Routledge. pp. 218-235.
    Digital practices in design, together with computer-assisted manufacturing (CAM), have inspired the reflection of philosophers, theorists, and historians over the last decades. Gilles Deleuze’s The Fold: Leibniz and the Baroque (1988) presents one of the first and most successful concepts created to think about these new design and manufacturing practices.1 Deleuze proposed a new concept of the technological object, which was inspired by Bernard Cache’s digital design practices and computer-assisted manufacturing. Deleuze compared Cache’s practices to Leibniz’s differential calculus-based notion of (...)
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  8. La déduction mathématique et la théorie physique. Exemple de solutions numériques physiquement utiles.Sara Franceschelli - 2014 - In Modéliser & simuler. Tome 2. Ed. Matériologiques.
    Cette étude montre comment le météorologue Edward Lorenz, dans deux articles de 1963 et 1964, explore les propriétés des systèmes chaotiques par des allers-retours entre une déduction mathématique (basée sur la théorie des systèmes dynamiques) et une étude des solutions numériques du système dit « de Lorenz » dans un régime d’instabilité. This study aims at showing how the metereologist Edward Lorenz, in two papers of 1963 and 1964, explores the properties of chaotic systems thanks to the interplay between a (...)
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  9. Morphogenèse. L'origine des formes.Sara Franceschelli (ed.) - 2006 - Paris: Belin.
     
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  10. Modéliser & simuler. Tome 2. Ed. Matériologiques.Sara Franceschelli (ed.) - 2014
     
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  11. René Thom. Oeuvres Mathématiques Complètes. Volume II.Sara Franceschelli (ed.) - 2019 - Société Mathématique de France.
     
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  12. The Routledge Companion to Biology in Art and Architecture.Sara Franceschelli (ed.) - 2016 - New York: Routledge.
     
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  13. Computer Simulations as Experiments.Anouk Barberousse, Sara Franceschelli & Cyrille Imbert - 2009 - Synthese 169 (3):557 - 574.
    Whereas computer simulations involve no direct physical interaction between the machine they are run on and the physical systems they are used to investigate, they are often used as experiments and yield data about these systems. It is commonly argued that they do so because they are implemented on physical machines. We claim that physicality is not necessary for their representational and predictive capacities and that the explanation of why computer simulations generate desired information about their target system is only (...)
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  14. Cellular automata, modeling, and computation.Anouk Barberousse, Sara Franceschelli & Cyrille Imbert - unknown
    Cellular Automata (CA) based simulations are widely used in a great variety of domains, fromstatistical physics to social science. They allow for spectacular displays and numerical predictions. Are they forall that a revolutionary modeling tool, allowing for “direct simulation”, or for the simulation of “the phenomenon itself”? Or are they merely models "of a phenomenological nature rather than of a fundamental one”? How do they compareto other modeling techniques? In order to answer these questions, we present a systematic exploration of (...)
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  15.  35
    Living a feminist life.Sara Ahmed - 2017 - Durham: Duke University Press.
    Feminism is sensational -- On being directed -- Willfulness and feminist subjectivity -- Trying to transform -- Being in question -- Brick walls -- Fragile connections -- Feminist snap -- Lesbian feminism -- Conclusion 1: A killjoy survival kit -- Conclusion 2: A killjoy manifesto.
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  16. Queer phenomenology: orientations, objects, others.Sara Ahmed - 2006 - Durham: Duke University Press.
    Introduction: find your way -- Orientations toward objects -- Sexual orientation -- The orient and other others -- Conclusion: disorientation and queer objects.
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  17.  31
    Inference in Argumentation: A Topics-Based Approach to Argument Schemes.Sara Greco & Eddo Rigotti - 2018 - Cham: Springer Verlag. Edited by Sara Greco.
    This book investigates the role of inference in argumentation, considering how arguments support standpoints on the basis of different loci. The authors propose and illustrate a model for the analysis of the standpoint-argument connection, called Argumentum Model of Topics. A prominent feature of the AMT is that it distinguishes, within each and every single argumentation, between an inferential-procedural component, on which the reasoning process is based; and a material-contextual component, which anchors the argument in the interlocutors’ cultural and factual common (...)
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  18. A phenomenology of whiteness.Sara Ahmed - 2007 - Feminist Theory 8 (2):149-168.
    The paper suggests that we can usefully approach whiteness through the lens of phenomenology. Whiteness could be described as an ongoing and unfinished history, which orientates bodies in specific directions, affecting how they `take up' space, and what they `can do'. The paper considers how whiteness functions as a habit, even a bad habit, which becomes a background to social action. The paper draws on experiences of inhabiting a white world as a non-white body, and explores how whiteness becomes worldly (...)
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  19. Network analyses in systems biology: new strategies for dealing with biological complexity.Sara Green, Maria Şerban, Raphael Scholl, Nicholaos Jones, Ingo Brigandt & William Bechtel - 2018 - Synthese 195 (4):1751-1777.
    The increasing application of network models to interpret biological systems raises a number of important methodological and epistemological questions. What novel insights can network analysis provide in biology? Are network approaches an extension of or in conflict with mechanistic research strategies? When and how can network and mechanistic approaches interact in productive ways? In this paper we address these questions by focusing on how biological networks are represented and analyzed in a diverse class of case studies. Our examples span from (...)
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  20.  22
    Ars Topica: The Classical Technique of Constructing Arguments From Aristotle to Cicero.Sara Rubinelli - 2009 - Dordrecht, Netherland: Springer.
  21.  90
    Biology meets Physics: Reductionism and Multi-scale Modeling of Morphogenesis.Sara Green & Robert Batterman - 2017 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 7161:20-34.
    A common reductionist assumption is that macro-scale behaviors can be described "bottom-up" if only sufficient details about lower-scale processes are available. The view that an "ideal" or "fundamental" physics would be sufficient to explain all macro-scale phenomena has been met with criticism from philosophers of biology. Specifically, scholars have pointed to the impossibility of deducing biological explanations from physical ones, and to the irreducible nature of distinctively biological processes such as gene regulation and evolution. This paper takes a step back (...)
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  22.  29
    Aging biomarkers and the measurement of health and risk.Sara Green & Line Hillersdal - 2021 - History and Philosophy of the Life Sciences 43 (1):1-23.
    Prevention of age-related disorders is increasingly in focus of health policies, and it is hoped that early intervention on processes of deterioration can promote healthier and longer lives. New opportunities to slow down the aging process are emerging with new fields such as personalized nutrition. Data-intensive research has the potential to improve the precision of existing risk factors, e.g., to replace coarse-grained markers such as blood cholesterol with more detailed multivariate biomarkers. In this paper, we follow an attempt to develop (...)
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  23.  28
    Precision medicine and the problem of structural injustice.Sara Green, Barbara Prainsack & Maya Sabatello - 2023 - Medicine, Health Care and Philosophy 26 (3):433-450.
    Many countries currently invest in technologies and data infrastructures to foster precision medicine (PM), which is hoped to better tailor disease treatment and prevention to individual patients. But who can expect to benefit from PM? The answer depends not only on scientific developments but also on the willingness to address the problem of structural injustice. One important step is to confront the problem of underrepresentation of certain populations in PM cohorts via improved research inclusivity. Yet, we argue that the perspective (...)
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  24.  92
    Revisiting generality in biology: systems biology and the quest for design principles.Sara Green - 2015 - Biology and Philosophy 30 (5):629-652.
    Due to the variation, contingency and complexity of living systems, biology is often taken to be a science without fundamental theories, laws or general principles. I revisit this question in light of the quest for design principles in systems biology and show that different views can be reconciled if we distinguish between different types of generality. The philosophical literature has primarily focused on generality of specific models or explanations, or on the heuristic role of abstraction. This paper takes a different (...)
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  25.  89
    Explanatory Integration Challenges in Evolutionary Systems Biology.Sara Green, Melinda Fagan & Johannes Jaeger - 2015 - Biological Theory 10 (1):18-35.
    Evolutionary systems biology (ESB) aims to integrate methods from systems biology and evolutionary biology to go beyond the current limitations in both fields. This article clarifies some conceptual difficulties of this integration project, and shows how they can be overcome. The main challenge we consider involves the integration of evolutionary biology with developmental dynamics, illustrated with two examples. First, we examine historical tensions between efforts to define general evolutionary principles and articulation of detailed mechanistic explanations of specific traits. Next, these (...)
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  26. Open Forum Imaginary Prohibitions: Some Preliminary Remarks on the Founding Gestures of the `New Materialism'.Sara Ahmed - 2008 - European Journal of Women's Studies 15 (1):23-39.
    We have no interest whatever in minimizing the continuing history of racist, sexist, homophobic, or otherwise abusive biologisms, or the urgency of their exposure, that has made the gravamen of so many contemporary projects of critique. At the same time, we fear — with installation of an automatic antibiologism as the unshifting tenet of `theory' — the loss of conceptual access to an entire thought-realm. I was left wondering what danger had been averted by the exclusion of biology. What does (...)
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  27.  95
    Design sans adaptation.Sara Green, Arnon Levy & William Bechtel - 2015 - European Journal for Philosophy of Science 5 (1):15-29.
    Design thinking in general, and optimality modeling in particular, have traditionally been associated with adaptationism—a research agenda that gives pride of place to natural selection in shaping biological characters. Our goal is to evaluate the role of design thinking in non-evolutionary analyses. Specifically, we focus on research into abstract design principles that underpin the functional organization of extant organisms. Drawing on case studies from engineering-inspired approaches in biology we show how optimality analysis, and other design-related methods, play a specific methodological (...)
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  28.  73
    Awe as a Scientific Emotion.Sara Gottlieb, Dacher Keltner & Tania Lombrozo - 2018 - Cognitive Science 42 (6):2081-2094.
    Awe has traditionally been considered a religious or spiritual emotion, yet scientists often report that awe motivates them to answer questions about the natural world, and to do so in naturalistic terms. Indeed, awe may be closely related to scientific discovery and theoretical advance. Awe is typically triggered by something vast (either literally or metaphorically) and initiates processes of accommodation, in which existing mental schemas are revised to make sense of the awe‐inspiring stimuli. This process of accommodation is essential for (...)
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  29.  54
    When one model is not enough: Combining epistemic tools in systems biology.Sara Green - 2013 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 44 (2):170-180.
    In recent years, the philosophical focus of the modeling literature has shifted from descriptions of general properties of models to an interest in different model functions. It has been argued that the diversity of models and their correspondingly different epistemic goals are important for developing intelligible scientific theories. However, more knowledge is needed on how a combination of different epistemic means can generate and stabilize new entities in science. This paper will draw on Rheinberger’s practice-oriented account of knowledge production. The (...)
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  30.  82
    Constraint‐Based Reasoning for Search and Explanation: Strategies for Understanding Variation and Patterns in Biology.Sara Green & Nicholaos Jones - 2016 - Dialectica 70 (3):343-374.
    Life scientists increasingly rely upon abstraction-based modeling and reasoning strategies for understanding biological phenomena. We introduce the notion of constraint-based reasoning as a fruitful tool for conceptualizing some of these developments. One important role of mathematical abstractions is to impose formal constraints on a search space for possible hypotheses and thereby guide the search for plausible causal models. Formal constraints are, however, not only tools for biological explanations but can be explanatory by virtue of clarifying general dependency-relations and patterning between (...)
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  31.  53
    A nation’s right to exclude and the Colonies.Sara Amighetti & Alasia Nuti - 2016 - Political Theory 44 (4):541-566.
    This essay contends that postcolonial migrants have a right to enter their former colonizing nations, and that these should accept them. Our novel argument challenges well-established justifications for restrictions in immigration-policies advanced in liberal nationalism, which links immigration controls to the nation’s self-determination and the legitimate preservation of national identity. To do so, we draw on postcolonial analyses of colonialism, in particular on Edward Said’s notion of “intertwined histories,” and we offer a more sophisticated account of national identity than that (...)
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  32. Collective Feelings.Sara Ahmed - 2004 - Theory, Culture and Society 21 (2):25-42.
    This article examines ‘collective feelings’ by considering how ‘others’ create impressions on the surfaces of bodies. Rather than considering ‘collective feeling’ as ‘fellow feeling’ or in terms of feeling ‘for’ the collective, the article suggests that how we respond to others in intercorporeal encounters creates the impression of a collective body. In other words, how we feel about others is what aligns us with a collective, which paradoxically ‘takes shape’ only as an effect of such alignments. The article considers different (...)
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  33.  37
    Adapting practice-based philosophy of science to teaching of science students.Sara Green, Hanne Andersen, Kristian Danielsen, Claus Emmeche, Christian Joas, Mikkel Willum Johansen, Caio Nagayoshi, Joeri Witteveen & Henrik Kragh Sørensen - 2021 - European Journal for Philosophy of Science 11 (3):1-18.
    The “practice turn” in philosophy of science has strengthened the connections between philosophy and scientific practice. Apart from reinvigorating philosophy of science, this also increases the relevance of philosophical research for science, society, and science education. In this paper, we reflect on our extensive experience with teaching mandatory philosophy of science courses to science students from a range of programs at University of Copenhagen. We highlight some of the lessons we have learned in making philosophy of science “fit for teaching” (...)
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  34.  51
    ‘Extreme’ organisms and the problem of generalization: interpreting the Krogh principle.Sara Green, Michael R. Dietrich, Sabina Leonelli & Rachel A. Ankeny - 2018 - History and Philosophy of the Life Sciences 40 (4):65.
    Many biologists appeal to the so-called Krogh principle when justifying their choice of experimental organisms. The principle states that “for a large number of problems there will be some animal of choice, or a few such animals, on which it can be most conveniently studied”. Despite its popularity, the principle is often critiqued for implying unwarranted generalizations from optimal models. We argue that the Krogh principle should be interpreted in relation to the historical and scientific contexts in which it has (...)
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  35.  19
    Mouse avatars of human cancers: the temporality of translation in precision oncology.Sara Green, Mie S. Dam & Mette N. Svendsen - 2021 - History and Philosophy of the Life Sciences 43 (1):1-22.
    Patient-derived xenografts are currently promoted as new translational models in precision oncology. PDXs are immunodeficient mice with human tumors that are used as surrogate models to represent specific types of cancer. By accounting for the genetic heterogeneity of cancer tumors, PDXs are hoped to provide more clinically relevant results in preclinical research. Further, in the function of so-called “mouse avatars”, PDXs are hoped to allow for patient-specific drug testing in real-time. This paper examines the circulation of knowledge and bodily material (...)
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  36.  7
    Numbers around Descartes: A preregistered study on the three-dimensional SNARC effect.Sara Aleotti, Francesco Di Girolamo, Stefano Massaccesi & Konstantinos Priftis - 2020 - Cognition 195 (C):104111.
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  37.  76
    Tracing Organizing Principles: Learning from the History of Systems Biology.Sara Green & Olaf Wolkenhauer - 2013 - History and Philosophy of the Life Sciences 35 (4):553-576.
    With the emergence of systems biology the notion of organizing principles is being highlighted as a key research aim. Researchers attempt to ‘reverse engineer’ the functional organization of biological systems using methodologies from mathematics, engineering and computer science while taking advantage of data produced by new experimental techniques. While systems biology is a relatively new approach, the quest for general principles of biological organization dates back to systems theoretic approaches in early and mid-20th century. The aim of this paper is (...)
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  38.  36
    “Let Me Tell You Why!”. When Argumentation in Doctor–Patient Interaction Makes a Difference.Sara Rubinelli & Peter J. Schulz - 2006 - Argumentation 20 (3):353-375.
    This paper throws some light on the nature of argumentation, its use and advantages, within the setting of doctor–patient interaction. It claims that argumentation can be used by doctors to offer patients reasons that work as ontological conditions for enhancing the decision making process, as well as to preserve the institutional nature of their relationship with patients. In support of these claims, selected arguments from real-life interactions are presented in the second part of the paper, and analysed by means of (...)
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  39.  82
    Can biological complexity be reverse engineered?Sara Green - 2015 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 53:73-83.
    Concerns with the use of engineering approaches in biology have recently been raised. I examine two related challenges to biological research that I call the synchronic and diachronic underdetermination problem. The former refers to challenges associated with the inference of design principles underlying system capacities when the synchronic relations between lower-level processes and higher-level systems capacities are degenerate. The diachronic underdetermination problem regards the problem of reverse engineering a system where the non-linear relations between system capacities and lower-level mechanisms are (...)
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  40.  10
    Twitter Activists’ Argumentation Through Subdiscussions: Theory, Method and Illustration of the Controversy Surrounding Sustainable Fashion.Sara Greco - 2023 - Argumentation 37 (1):1-23.
    “Why are millions of dollars worth of orders being left unpaid?”. With tweets like this questioning brands’ policies, activists advocating for sustainable fashion re-discuss material starting points that are assumed by fashion brands, who argue that they are sustainable because they care about their workers’ conditions. This paper argues that activists use tweets to open _subdiscussions on material starting points_ to engage citizens and consumers, re-discussing factual _data_ that brands take for granted, such as the fact that they provide fair (...)
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  41.  14
    Examining the Role of Dyadic Coping on the Marital Adjustment of Couples Undergoing Assisted Reproductive Technology.Sara Molgora, Valentina Fenaroli, Chiara Acquati, Arianna De Donno, Maria Pia Baldini & Emanuela Saita - 2019 - Frontiers in Psychology 10.
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  42.  40
    Personalizing Medicine: Disease Prevention in silico and in socio.Sara Green & Henrik Vogt - 2016 - Humana Mente 9 (30).
    Proponents of the emerging field of P4 medicine argue that computational integration and analysis of patient-specific “big data” will revolutionize our health care systems, in particular primary care-based disease prevention. While many ambitions remain visionary, steps to personalize medicine are already taken via personalized genomics, mobile health technologies and pilot projects. An important aim of P4 medicine is to enable disease prevention among healthy persons through detection of risk factors. In this paper, we examine the current status of P4 medicine (...)
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  43.  19
    Using Argumentative Tools to Understand Inner Dialogue.Sara Greco - 2017 - Argumentation 31 (2):331-358.
    The starting point of this paper is the acknowledgement that individual reasoning, understood as inner dialogue, and social argumentation, albeit they are two different phenomena, share some similarities. On this basis, this paper sets out to apply instruments from argumentation theory to inner dialogue in order to better explain it. Within this framework, some limitations to the study of inner dialogue are also discussed; and methodological suggestions are provided in order to grasp what could be considered data on “inner dialogue” (...)
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  44.  16
    Comment: Developing and Maintaining High-Quality Relationships via Emotion.Sara B. Algoe - 2020 - Emotion Review 12 (4):276-278.
    This comment addresses opportunities for understanding the social functions of emotion by taking a developmental perspective. I agree that understanding emotions and their development will meaningf...
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  45.  32
    Scale Dependency and Downward Causation in Biology.Sara Green - 2018 - Philosophy of Science 85 (5):998-1011.
    This paper argues that scale-dependence of physical and biological processes offers resistance to reductionism and has implications that support a specific kind of downward causation. I demonstrate how insights from multiscale modeling can provide a concrete mathematical interpretation of downward causation as boundary conditions for models used to represent processes at lower scales. The autonomy and role of macroscale parameters and higher-level constraints are illustrated through examples of multiscale modeling in physics, developmental biology, and systems biology. Drawing on these examples, (...)
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  46.  21
    “I Have Fought for so Many Things”: Disadvantaged families’ Efforts to Obtain Community-Based Services for Their Child after Genomic Sequencing.Sara L. Ackerman, Julia E. H. Brown, Astrid Zamora & Simon Outram - 2023 - AJOB Empirical Bioethics 14 (4):208-217.
    Background Families whose child has unexplained intellectual or developmental differences often hope that a genetic diagnosis will lower barriers to community-based therapeutic and support services. However, there is little known about efforts to mobilize genetic information outside the clinic or how socioeconomic disadvantage shapes and constrains outcomes.Methods We conducted an ethnographic study with predominantly socioeconomically disadvantaged families enrolled in a multi-year genomics research study, including clinic observations and in-depth interviews in English and Spanish at multiple time points. Coding and thematic (...)
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  47. A Philosophical Evaluation of Adaptationism as a Heuristic Strategy.Sara Green - 2014 - Acta Biotheoretica 62 (4):479-498.
    Adaptationism has for decades been the topic of sophisticated debates in philosophy of biology but methodological adaptationism has not received as much attention as the empirical and explanatory issues. In addition, adaptationism has mainly been discussed in the context of evolutionary biology and not in fields such as zoophysiology and systems biology where this heuristic is also used in design analyses of physiological traits and molecular structures. This paper draws on case studies from these fields to discuss the productive and (...)
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  48.  40
    Reason and Imagination in Charles S. Peirce.Sara Barrena - 2013 - European Journal of Pragmatism and American Philosophy 5 (1).
    Charles S. Peirce held a view of human reason as creative. The objective of this article is to explore more deeply the Peircean conception of imagination, indispensable for the correct functioning of reason. The connection of reason and imagination is necessary in order to be able to interpret the world, to advance towards the truth and to direct our own actions. In this paper I will explain the principal forms in which these faculties interact, and will provide examples taken from (...)
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  49. Injustice in families: Assault and domination.Sara Ruddick - 1995 - In Virginia Held (ed.), Justice and care: essential readings in feminist ethics. Boulder, Colo.: Westview Press. pp. 203--223.
  50.  58
    Teaching argumentation theory to doctors: Why and what.Sara Rubinelli & Claudia Zanini - 2012 - Journal of Argumentation in Context 1 (1):66-80.
    This paper supports the need for health professionals to be trained in argumentation theory, by illustrating the challenges that they face in interacting with patients and according to the different models of consultation that patients prefer. While there is no ideal model of consultation that can be promoted universally, the ability to construct arguments in support of health professionals’ points of view, as well as the ability to engage in critical discussion with patients, translate in essential skills for reaching patients’ (...)
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