In the mathematics education research literature, there is a growing body of scholarship on how mathematicians practice their craft. The purpose of this chapter is to survey some of this literature and explain how it can contribute to the philosophy of mathematical practice. We first describe how mathematics educators use empirical methodologies to investigate the behaviors of mathematicians and argue that findings from these studies can inform the philosophy of mathematical practice. We then illustrate this by summarizing research on mathematicians’ (...) understandings and mathematicians’ proof reading. (shrink)

In a 2022 paper, Hamami claimed that the orthodox view in mathematics is that a proof is rigorous if it can be translated into a derivation. Hamami then developed a descriptive account that explains how mathematicians check proofs for rigor in this sense and how they develop the capacity to do so. By exploring introductory texts in computability theory, we demonstrate that Hamami’s descriptive account does not accord with actual mathematical practice with respect to computability theory. We argue instead for (...) an alternative account in which imagination, anticipation, and interpretations of natural language play roles in establishing mathematical rigor. (shrink)

The issue of what constitutes a valid logical inference is a difficult question. At a minimum, we believe a permissible step in a proof must provide the reader with rational grounds to believe that the new step is a logically necessary consequence of previous assertions. However, this begs the question of what constitutes these rational grounds. Formalist accounts typically describe valid rules of inferences as those that can be found by applying one of the explicit rules of inference in the (...) formal system in which the proof is couched. However, philosophers of mathematics find such a description unhelpful because many inferences in the proofs that mathematicians actually produce cannot be expressed in a formal language, at least not without seriously distorting the semantic content of the inference (e.g., Larvor, 2012). In this chapter, we investigate mathematicians’ perceptions of a particular kind of inference in a particular setting. Specifically, we shed light on what types of graphical inferences mathematicians find permissible in a real analysis proof. Following Larvor (in press), we examine mathematicians’ reactions to metrical graphical inferences (i.e., inferences whose validity depends on the accuracy of the graph that was drawn and whose validity can be changed by minor deformations) and nonmetrical graphical inferences (i.e., inferences whose validity does not depend on a the accuracy of the graph and whose validity is not vulnerable to local deformations). The goal of this chapter is threefold. First, we demonstrate that most mathematicians reject metrical graphical inferences as impermissible in a real analysis proof. Second, we show that many mathematicians regard nonmetrical graphical inferences as permissible in a real analysis proofs. Third, we illustrate how mathematicians collectively disagree on the permissibility of nonmetrical inferences. (shrink)

In this paper, we explore the role of syntactic representations in set theory. We highlight a common inferential scheme in set theory, which we call the Syntactic Representation Inferential Scheme, in which the set theorist infers information about a concept based on the way that concept can be represented syntactically. However, the actual syntactic representation is only indicated, not explicitly provided. We consider this phenomenon in relation to the derivation indicator position that asserts that the ordinary proofs given in mathematical (...) discourse indicate syntactic derivations in a formal logical system. In particular, we note that several of the arguments against the derivation indicator position would seem to imply that set theorists could gain no benefits from the syntactic representations of concepts indicated by their definitions, yet set theorists clearly do. (shrink)

Traditional models of mathematical proof describe proofs as sequences of assertion where each assertion is a claim about mathematical objects. However, Tanswell observed that in practice, many proofs do not follow these models. Proofs often contain imperatives, and other instructions for the reader to perform mathematical actions. The purpose of this paper is to examine the role of instructions in proofs by systematically analyzing how instructions are used in Kunen’s Set theory: An introduction to independence proofs, a widely used graduate (...) text in set theory. I use Kunen’s text to describe how instructions and constructions in proof work in mathematical practice and explore epistemic consequences of how proofs are read and understood. (shrink)

In this article, we report a study in which 109 research-active mathematicians were asked to judge the validity of a purported proof in undergraduate calculus. Significant results from our study were as follows: (a) there was substantial disagreement among mathematicians regarding whether the argument was a valid proof, (b) applied mathematicians were more likely than pure mathematicians to judge the argument valid, (c) participants who judged the argument invalid were more confident in their judgments than those who judged it valid, (...) and (d) participants who judged the argument valid usually did not change their judgment when presented with a reason raised by other mathematicians for why the proof should be judged invalid. These findings suggest that, contrary to some claims in the literature, there is not a single standard of validity among contemporary mathematicians. (shrink)

This article addresses the ability of Parallel Distributed Processing (PDP) networks to generate stagewise cognitive development in accordance with Piaget's theory of cognitive epigenesis. We carried out a replication study of the simulation experiments by McClelland (1989) and McClelland and Jenkins (1991) in which a PDP network learns to solve balance scale problems. In objective tests motivated from catastrophe theory, a mathematical theory of transitions in epigenetical systems, no evidence for stage transitions in network performance was found. It is concluded (...) that PDP networks lack the ability to recover the positive outcomes of analogous catastrophe analyses of real cognitive developmental data. In an attempt to further characterize the learning behaviour of PDP networks, we carried out a second simulation study using the discrimination‐shift paradigm. The results thus obtained indicate that PDP learning is compatible with the learning of stimulus‐response relationships, not with the acquisition of mediating rules such as conceived in (neo‐)Piagetian theory. In closing, we speculate about the feasibility of simulating stagewise development with alternative network architectures. (shrink)

The first four chapters of Max Weber's Economy and Society presented by Talcott Parsons in 1947 as Theory of Social and Economic Organization present a coherent and complete analysis of social, economic and political structures based upon a consistent theory of social action and its understanding. Parsons did not see them this way. His lengthy introduction sought to insert them into his own “action frame of reference”, and his rearrangement of the text made it difficult for a reader to (...) understand why it was constructed the way that it is. This essay describes how Parsons came to be principal translator and editor of the text, examines the changes that he made to it, and links his editorial practice to the analytical procedures that he followed in his Structure of Social Action. ☆ This essay is developed from a paper originally presented in June 2005 at a conference on Max Weber's Basic Sociological Concepts at ZiF, Bielefeld University; an earlier version of the present paper was published as “Talcott Parsons als Übersetzer der ‘Soziologischen Grundbegriffe’ Max Webers”. Max Webers ‘Grundbegriffe’. Kategorien der kultur- und sozialwissenschaftlichen Forschung. Ed. Klaus Lichtblau. (Wiesbaden: Verlag für Sozialwissenschaften, 2006) 337–366. (shrink)

Introduction -- Modernity, politics and Max Weber -- One-sided rationalization: Habermas on modernity, discourse and emancipation -- Critiquing Habermas: intersubjectivity, ethics and norm-free sociality -- The burden of our times: Arendt on modern oblivion and the promise of politics -- Judging Arendt: citizenship, action and the scope of politics -- The new dark age: MacIntyre on bureaucratic individualism and the hope for an ethical polity -- Engaging MacIntyre: flourishing, modernity and political struggle -- Closing reflections: ethics, politics and strategy (...) in the present. (shrink)

If sociology is about society must it not also be about morality? In the nineteenth and early twentieth centuries, the identification between sociology and morality was clear cut; Marx, Durkheim, Weber, Spencer, and Veblen all dealt with moral issues and one might argue that they saw themselves as engaged in a moral vocation. Now, one might argue that the connections between sociology and moral currents have become more tenuous. Moral Culture examines what it means to be moral in contemporary (...) social and cultural life. Author Keith Tester takes the highly original and revealing step of exploring how violence today, and throughout history, affects the relatively safe and secure people who live in the west and who tend to know horror only through television and cinema screens. The book raises questions about the meaning and significance of massacres in the Balkans, Rwanda and, rather more historically, the Holocaust, and the slaughter of Vietnamese peasants by American soldiers in My Lai. It also discusses how Adolf Eichmann and the men of Charlie Company might be different from or similar to us. It answers questions about whether this is a time of moral decay or more seriously, the collapse of moral Civilization. Sociologists often claim that they make a virtue of being relevant and objective, but few have attacked these issues with the urgency and originality that Keith Tester displays in this work. Each chapter provides a historically aware account of a moral problem making it especially relevant reading for students of cultural studies, sociology, political science, and moral philosophy. (shrink)

In contrast to political realism's equation of the `political' with domination, Hannah Arendt understood the `political' as a relation of friendship utterly opposed to the use of violence. This article offers a critique of that understanding. It becomes clear that Arendt's challenge to realism, as exemplified by Max Weber, succeeds on account of a dubious redefinition of the `political' that is the reverse image of the one-sided vision of politics she had hoped to contest. Questioning this paradoxical turn leads (...) to a critique of Arendt's separation of violence and power and, consequently, her attempt to insulate a politics of friendship from one of hostility and coercion. However, political realism is not thereby affirmed. What is required, instead, is a view of the `political' that accepts the interwoven-ness of violence and power but also emphasizes the normative ideals of moderation and care. Key Words: Hannah Arendt • enmity • friendship • moderation • the `political' • power • realism • violence • Max Weber. (shrink)

SummaryDuring the 1950s at the latest, Max Weber became a ‘founding father’ of sociology, chiefly on the basis of a restricted set of canonical writings and without any consideration of his wider relationships to law, economics and politics. During the last ten years of his life he was responsible for a major collaborative work, the Grundriss der Sozialökonomik—Outline of Social Economics. The title was of his own choosing; and so it might well shed new light on his work if (...) we consider how this work was organised, and how Economy and Society, written as a contribution to this handbook, was intended to form part of it. (shrink)

Keith Ansell-Pearson, An Introduction to Nietzsche as Political Thinker (Cambridge: Cambridge University Press, 1994) hb: 0-521-41722-8. pb: 0-521-42721-5. Paul Patton, ed., Nietzsche, Feminism and Political Theory (London: Routledge. 1993) 0-4150-8256-0. Lester M. Hunt, Nietzsche and the Origin of Virtue (London: Routledge, 1993) 0-4150-9580-8. David Owen, Maturity and Modernity. Nietzsche, Weber, Foucault and the Ambivalence of Reason (London: Routledge, 1994) 0-4150-5398-6. Peter Lassmann and Ronald Spiers, eds., Weber: Political Writings (Cambridge: Cambridge University Press. 1994) hb: 0-521 -39312-4. pb: (...) 0-521 -39719-7. Friedrich Nietzsche, On the Genealogy of Morality and Other Writings, ed. Keith Ansell-Pearson, tr. Carol Diethe (Cambridge University Press, 1994) hb: 0-521-40459-2. pb: 0-521-40610-2. (shrink)

I dedicate this essay to the memory of the late Wolfgang Mommsen—the subject would have been congenial to him. It is one of a series of offshoots from a central project: a scholarly edition of Max Weber's Protestant Ethic with commentary. When I first told Prof. Mommsen of my plan in 1994 he looked me full in the face and gave a characteristic growl: “All that work!” Here was a man who knew what he was about. My thanks to (...) Ross McKibbin and Keith Tribe for reading this paper in draft. The article begins by examining Max Weber's relations with Lujo Brentano, much the most important “precursor” to Weber in the field of economics. In particular, Brentano conducted a form of parallel inquiry into the rise of ‘the spirit of capital’ in England 35 years before Weber looked for the origins of “spirit” of capitalism there, and the contrast between these two ideas casts much light both on Brentano and on Weber's Protestant Ethic. This personal history leads into a broader history of the transition in German economic thought between the 1860s – the formative decade for Brentano but also the era of Marx's Capital – and that of Weber's generation coming to maturity c.1890. Marx and Weber remain the two great canonical thinkers and original minds; but any authentic historical comparison between Marx and Weber must take in Brentano. The essence of the contrast between the generations is that between Weber's novel conception of an ethical ‘capitalism’, and the materialism and naturalism underpinning Brentano's and Marx's ‘capital’, although Weber and Brentano are alike as liberals, democrats and bourgeois. ☆ Some abbreviations for Weber: AfSS for Archiv für Sozialwissenschaft und Sozialpolitik; GARS for Gesammelte Aufsätze zur Religionssoziologie (Tübingen, 1920) vol. i; WL for Gesammelte Aufsätze zur Wissenschaftslehre (Tübingen, 1968); Grundriss for Grundriss zu den Vorlesungen über Allgemeine (“theoretische”) Nationalökonomie [1898], repr. Tübingen, 1990; MWG for Max Weber Gesamtausgabe ed. Horst Baier et al. (Tübingen, 1984); Briefe for letters by Weber in this edition; ‘Nachlaß Max Weber’ for unpublished letters from the Geheimes Staatsarchiv, Berlin-Dahlem, VI. HA Nachlaß Max Weber. Lebensbild for Marianne Weber, Max Weber: Ein Lebensbild (Tübingen, 1926); Zohn for idem, Max Weber. A Biography (New Brunswick, 1988) tr. Harry Zohn. For Brentano: Der wirtschaftende Mensch for Der wirtschaftende Mensch in der Geschichte (Leipzig, 1923); Konkrete Grundbedingungen for Konkrete Grundbedingungen der Volkswirtschaft (Leipzig, 1924); Der tätige Mensch for Der tätige Mensch und die Wissenschaft von der Wirtschaft (Marburg, 2006) ed. R. Bräu, H.G. Nutzinger. ‘Die Entwickelung der Wertlehre’ for ‘Die Entwickelung der Wertlehre’, Sitzungsberichte der Königlich Bayerischen Akademie der Wissenschaften. Philosophisch-philologische und historische Klassen. Jahrgang 1908, 3. Abhandlung (15 Feb. 1908), 1–84; ‘Theorie der Bedürfnisse’ for ‘Versuch einer Theorie der Bedürfmisse’, ibid., 10. Abhandlung (5 Dec. 1908), 1–79; ‘Die Malthussche Lehre’ for ‘Die Malthussche Lehre und die Bevölkerungsbewegung der letzten Decennien’ [1909], Abhandlungen der historischen Klasse der Königlich Bayerischen Akademie der Wissenschaften XXIV (1906–1909), 565–625, 1*–39*. (shrink)

Contemporary virtue ethics was revolutionized by Alasdair MacIntyre’s reconfiguration using practices as the starting point for understanding virtues. However, MacIntyre has very pointedly excluded the professions of the financial world from the reformulation. He does not count these professions as practices, and further charges that virtue would actually hinder or even rule out one’s pursuit of these professions. This paper addresses three tasks, in regard to the financial profession of investment advising. First, the paper lays out MacIntyre’s soon-to-be-published charges against (...) the investment world, as specified to this profession. Second, it sets forth the role function of investment advising and shows that it does possess internal goods—the crucial aspect of practices disputed by MacIntyre in this case—including goods of production and goods of performance. Third, it demonstrates that this function, and the goods tied to it, cannot be achieved apart from the virtuous pursuit of the profession, thereby showing that MacIntyre’s charges are mistaken. Investment advising is shown to be a virtue-based practice, and the groundwork is laid for showing that other financial professions are so, as well. (shrink)

This introductory text is written for students faced with the question "what is history?

Philosophers and scientists have studied sensory perception and, in particular, vision for many years. Increasingly, however, they have become interested in the nonvisual senses in greater detail and the problem of individuating the senses in a more general way. The Aristotelian view is that there are only five external senses—smell, taste, hearing, touch, and vision. This has, by many counts, been extended to include internal senses, such as balance, proprioception, and kinesthesis; pain; and potentially other human and nonhuman senses. This (...) “multisensory turn” has been driven partly by developments in contemporary psychology and neuroscience, which have revealed a host of complex interrelations and interactions between sensory modalities previously thought to be distinct. Contrasts between modalities and other crossmodal phenomena, including multisensory integration, synesthesia, and sensory substitution, have also begun to receive more attention in a burgeoning scientific and philosophical literature on multisensory perception and other crossmodal effects. This article focuses on recent empirically informed contributions to the philosophy of perception, as well as key scientific works that provide important background information and insights into the nature of the senses and sensory perception. Indeed, one of the lessons of the multisensory turn, and of contemporary philosophy of mind more generally, is that philosophers ignore this body of empirical research at their peril because many human and animal senses turn out to be richer and more complex than philosophers and scientists had previously imagined, making this a fruitful area for interdisciplinary interaction and research. (shrink)

The fact that humans cooperate with nonkin is something we take for granted, but this is an anomaly in the animal kingdom. Our species’ ability to behave prosocially may be based on human-unique psychological mechanisms. We argue here that these mechanisms include the ability to care about the welfare of others (other-regarding concerns), to “feel into” others (empathy), and to understand, adhere to, and enforce social norms (normativity). We consider how these motivational, emotional, and normative substrates of prosociality develop in (...) childhood and emerged in our evolutionary history. Moreover, we suggest that these three mechanisms all serve the critical function of aligning individuals with others: Empathy and other-regarding concerns align individuals with one another, and norms align individuals with their group. Such alignment allows us to engage in the kind of large-scale cooperation seen uniquely in humans. (shrink)

I will be concerned with only one problem about truth which is raised by the diversity of religions which exist in the world. The problem is this: many religions claim to state truths about the nature of the universe and human destiny which are important or even necessary for human salvation and ultimate well-being. Many of these truths seem to he incompatible; yet there is no agreed method for deciding which are to he accepted; and equally intelligent, informed, virtuous and (...) holy people belong to different faiths. It seems, therefore, that a believing member of any one tradition is compelled to regard all other traditions as holding false beliefs and therefore as not leading to salvation. Since each faith forms a minority of the world's population, all religious believers thus seem committed to saying that most intelligent, virtuous and spiritually devoted people cannot know the truth or attain salvation. This is a problem, because it is in tension with the belief, held by many traditions, that the supremely real being is concerned for the salvation of all rational creatures. How can this he so if, through no fault of their own, most creatures cannot come to know the truth and thereby attain salvation? (shrink)

In this engaging sequel to Rethinking History , Keith Jenkins argues for a re-figuration of historical study. At the core of his survey lies the realization that objective and disinterested histories as well as historical 'truth' are unachievable. The past and questions about the nature of history remain interminably open to new and disobedient approaches. Jenkins reassesses conventional history in a bold fashion. His committed and radical study presents new ways of 'thinking history', a new methodology and philosophy and (...) their impact on historical practice. This volume is written for students and teachers of history, illuminating and changing the core of their discipline. (shrink)

Keith DeRose presents, develops, and defends original solutions to two of the stickiest problems in epistemology: skeptical hypotheses and the lottery problem. He deploys a powerful version of contextualism, the view that the epistemic standards for the attribution of knowledge vary with context.

Objects appear different as the illumination under which they are perceived varies. This fact is sometimes thought to pose a problem for the view that colours are mind-independent properties: if a coloured object appears different under different illuminations, then under which illumination does the object appear the colour it really is? I argue that given the nature of natural daylight, and certain plausible assumptions about the nature of the colours it illuminates, there is a non-arbitrary reason to suppose that it (...) is under natural daylight that we are able to perceive the real colours of objects. (shrink)

Why History? is a compelling introduction to the issue of history and ethics. Designed to provoke discussion, the book asks whether and why a good knowledge and understanding of the past is desirable. In the context of current postmodern thinking, Keith Jenkins suggests that the goal of "learning lessons from the past" actually means learning lessons from stories written by historians and others. If the past as history has no foundation, can anything ethical be gained from history? Daring and (...) controversial, Why History? presents liberating challenges to history and ethics, proposing that we have reached an emancipatory moment which is well beyond the "end of history.". (shrink)

David Hume’s arguments against believing reports of miracles are shown to be very weak. Laws of nature, I suggest, are best seen not as exceptionless rules but as context-dependent realizations of natural powers. In that context miracles transcend the natural order not as "violations" but as intelligible realizations of a divine supernatural purpose. Miracles are not parts of scientific theory but can be parts of a web of rational belief fully consistent with science. (edited).

In his account of visual perception, Thomas Reid describes visible figure as both ‘real and external’ to the eye and as the ‘immediate object of sight’. These claims appear to conflict with Reid's direct realism, since if the ‘immediate’ object of vision is also its direct object, then sight would be perceptually indirect due to the role of visible figure as a perceptual intermediary. I argue that this apparent threat to Reid's direct realism may be resolved by understanding visible figure (...) as the set of geometrical properties that holds between an object's visible surfaces and some particular perspective or point of view. On this relational interpretation of visible figure, and once an ambiguity over the use of the term ‘object’ is resolved, Reid's account of vision is both epistemically and perceptually direct, as well as consistent with his account of the other senses and doctrine of signs. (shrink)

Keith DeRose presents, develops, and defends original solutions to two of the stickiest problems in epistemology: skeptical hypotheses and the lottery problem. He deploys a powerful version of contextualism, the view that the epistemic standards for the attribution of knowledge vary with context.

Keith Jenkins; The Dogma of Nietzsche’s Zarathustra, Journal of Philosophy of Education, Volume 16, Issue 2, 30 May 2006, Pages 251–254, https://doi.org/10.1111.

Explores ten questions that consider if religious beliefs can survive in the scientific age.

When Wet’suwet’en matriarch Freda Huson declared that ‘reconciliation is dead’ and called on supporters to ‘Shut Down Canada’, activists responded with a nationwide series of blockades and occupations. Many commenters, even those sympathetic to the Wet’suwet’en, rushed to defend the idea of reconciliation. Such responses fail to take the contributions this movement offers to decolonial thought seriously. Drawing on interviews with movement participants, I explore what participants mean by reconciliation and what they intend by declaring it dead, showing how participants (...) reject forms of decolonization that center the needs of the settler state. I also explore Land Back as an emerging, grassroots alternative to reconciliation that centers the resurgence of Indigenous governance systems in place of the settler state. Finally I explore settlers’ place within this project and considers its relation to the resurgence school of thought. (shrink)

P EM Manifestos for History /EM is a thought-provoking and controversial text that, through a star studded collection of essays, presents a wide ranging ...

This book is an extended discussion of individualism in the philosophy of mind.

From epic to limerick, novel to anecdote, literary narratives engage and entertain us. From autobiography and biography to accounts of familial generations, narratives define communities. Myths and histories loom large in religious traditions as well. Recently, the importance of narrative to ethics and religion has become a pervasive theme in several scholarly disciplines. In the essays presented here, a distinguished roster of scholars addresses a range of issues associated with this theme, focusing especially on questions concerning narrative's contribution to knowledge.

God, who is an omnipotent, omniscient, and omnibenevolent Creator and Providence, exists and There is evil are logically compatible claims. God exists, If God exists, then He has a morally sufficient reason for allowing any evil that He does allow , and There is evil is a consistent triad of propositions. Thus any pair from that triad is also consistent. Thus God exists and There is evil are logically compatible. But this does not settle the question as to whether the (...) truth of There is evil in the world has such consequences for theism as making it highly improbable that God exists or making it unreasonable to believe that God exists . That propositions P and Q are logically compatible does not entail that one does not provide powerful evidence against the other. In particular, it has seemed that some actual evils are gratuitous or in some manner just could not fit into a God-made world. Thus the simple argument is offered that: There are gratuitous evils; If there are gratuitous evils, then there is no God; so: There is no God. I will call this simple argument the ‘root argument’, for it is this argument and sophistications of it that will occupy us hereafter. (shrink)

This article engages with the arguments forwarded by Perez Zagorin against the possible consequences of postmodernism for history as it is currently conceived of particularly in its "proper" professional/academic form . In an overtly positioned response which issues from a close reading of Zagorin's text, I argue that his all-too-typical misunderstandings of postmodernism need to be "corrected"-not, however, to make postmodernism less of a threat to "history as we have known it," or to facilitate the assimilation of its useful elements (...) while exorcising its "extremes." My "corrections" instead forward the claim that, understood positively and integrated into those conditions of postmodernity which postmodernism variously articulates at the level of theory, such theory signals the possible "end of history," not only in its metanarrative styles but also in that particular and peculiar professional genre Zagorin takes as equivalent to history per se. And I want to argue that if this theory is understood in ways which choose not to give up the "discourse of emancipation" after the failure of its first attempt in the "experiment of modernity," then this ending can be considered "a good thing.". (shrink)

BackgroundDepressive disorders are a common form of psychiatric illness and cause significant disability. Regulation authorities, the medical profession and the public require high safety standards for antidepressants to protect vulnerable psychiatric patients. Ketamine is a dissociative anaesthetic and a derivative of a hallucinogen. Its abuse is a major worldwide public health problem. Ketamine is a scheduled drug and its usage is restricted due to its abuse liability. Recent clinical trials have reported that ketamine use led to rapid antidepressant effects in (...) patients suffering from treatment-resistant depression. However, various flaws in study designs, and possible biased reporting of results, may have influenced those findings. Further analyses of ketamine use are needed to ensure patient safety.DiscussionThe use of ketamine in research and treatment of depressive disorders is controversial. Recently, mental health professionals raised ethical concerns about an ongoing ketamine trial in the UK. Also, a Canadian agency reviewed the existing evidence and did not recommend prescribing ketamine to treat depressive disorders. Findings obtained from tightly controlled research settings cannot be easily translated to clinical practice as substance abuse is commonly comorbid with depressive disorders. An effective antidepressant should reduce severity of depressive symptoms without liability problems. Although the US FDA has not approved the use of ketamine to treat depressive disorders, some psychiatrists offer off-label repeat prescription of ketamine. Prescribing ketamine for treating depressive disorders requires substantial empirical evidence. Clinicians should also consider research findings on ketamine abuse. Depressive disorders can be chronic conditions and the current evidence does not rule out the risk of substance abuse after repeat prescription of ketamine. Off-label ketamine use in treating depressive disorders may breach ethical and moral standards, especially in countries seriously affected by ketamine abuse. This article presents two real-world clinical vignettes which highlight ethical principles and theories, including autonomy, nonmaleficience, fidelity and consequentialism, as related to off-label ketamine use.ConclusionWe urge clinicians to minimise the risk of harming patients by considering the empirical evidence on ketamine properties and attempting all standard antidepressant therapies before considering the off-label use of ketamine. (shrink)

RESUMENEn este artículo la risa se explica a través de la conocida teoría de la risa como una respuesta ante la incongruencia. Con base en lo anterior, la autora compara dos tipos de respuesta ante la incongruencia: aquella que pretende resolver la incongruencia, a saber, la filosofía, y aquella que la festeja sin remediarla: la risa. Y es que la tragedia y la comedia, el llanto y la risa, tienen en el fondo un mismo origen, tanto como obras de arte, (...) en la antigua Grecia, como en la vida humana.PALABRAS CLAVERISA, FILOSOFÍA, TRAGEDIA, COMEDIA, INCONGRUENCIA, RESOLVERABSTRACTIn this paper, laughter is explained through the well-known incongruence theory, i.e. as a way to deal with incongruence. The author compares two different ways of acting upon incongruence: one of them is to try to resolve it by setting a rational order and the other one is to take it as it is, accept it, and laugh. Tragedy and comedy, just like crying and laughing, have both the same origin, as works of art in ancient Greece, and also in human life.KEY WORDSLAUGHTER, PHILOSOPHY, TRAGEDY, COMEDY, INCONGRUENCE, RESOLVE. (shrink)