Spatiotemporal regulation of the biochemical information is often linked to supramolecular organizations proteins and nucleic acids, the driving forces of which have yet to be elucidated. Although the critical role of multivalency in phase transition has been recognized, the organization principles of higher-order structures need to be understood. Here, we present a fuzzy mathematical framework to handle the heterogeneity of interactions patterns and the resultant multiplicity of conformational states in protein assemblies. In this model, redundant binding motifs can establish simultaneous (...) and partial interactions with multiple targets. We demonstrate that these multivalent, weak contacts facilitate polymer formation, while recapitulating the observed valency-dependence. In addition, the impact of linker dynamics and motif binding affinity, as well as the interplay between the two effects was studied. Our results support that fuzziness is a critical factor in driving higher-order protein organizations, and this could be used as a general framework to simulate different kinds of supramolecular assemblies. (shrink)

The present article proposes an integration between cultural psychology and developmental science. Such an integration would draw on the cultural-psychology principle of culture-psyche interactions, as well as on the developmental-science principle of person↔︎context relations. Our proposed integration centers on acculturation, which is inherently both cultural and developmental. Specifically, we propose that acculturation is governed by specific transactions between the individual and the cultural context, and that different types of international migrants (e.g., legal immigrants, undocumented immigrants, refugees, asylum seekers, crisis migrants) (...) encounter quite different culture-psyche interactions and person↔︎context relations. We outline the ways in which various acculturation-related phenomena, such as acculturation operating at macro-level versus micro-level time scales, can be viewed through cultural and developmental lenses. The article concludes with future directions in research on acculturation as an intersection of cultural and developmental processes. (shrink)

Is the societal-level of analysis sufficient today to understand the values of those in the global workforce? Or are individual-level analyses more appropriate for assessing the influence of values on ethical behaviors across country workforces? Using multi-level analyses for a 48-society sample, we test the utility of both the societal-level and individual-level dimensions of collectivism and individualism values for predicting ethical behaviors of business professionals. Our values-based behavioral analysis indicates that values at the individual-level make a more significant contribution to (...) explaining variance in ethical behaviors than do values at the societal-level. Implicitly, our findings question the soundness of using societal-level values measures. Implications for international business research are discussed. (shrink)

This article provides current Schwartz Values Survey (SVS) data from samples of business managers and professionals across 50 societies that are culturally and socioeconomically diverse. We report the society scores for SVS values dimensions for both individual- and societal-level analyses. At the individual-level, we report on the ten circumplex values sub-dimensions and two sets of values dimensions (collectivism and individualism; openness to change, conservation, self-enhancement, and self-transcendence). At the societal-level, we report on the values dimensions of embeddedness, hierarchy, mastery, affective (...) autonomy, intellectual autonomy, egalitarianism, and harmony. For each society, we report the Cronbach’s α statistics for each values dimension scale to assess their internal consistency (reliability) as well as report interrater agreement (IRA) analyses to assess the acceptability of using aggregated individual level values scores to represent country values. We also examined whether societal development level is related to systematic variation in the measurement and importance of values. Thus, the contributions of our evaluation of the SVS values dimensions are two-fold. First, we identify the SVS dimensions that have cross-culturally internally reliable structures and within-society agreement for business professionals. Second, we report the society cultural values scores developed from the twenty-first century data that can be used as macro-level predictors in multilevel and single-level international business research. (shrink)

A partition $\{C_i\}_{i\in I}$ of a Boolean algebra $\cS$ in a probability measure space $(\cS,p)$ is called a Reichenbachian common cause system for the correlated pair $A,B$ of events in $\cS$ if any two elements in the partition behave like a Reichenbachian common cause and its complement, the cardinality of the index set $I$ is called the size of the common cause system. It is shown that given any correlation in $(\cS,p)$, and given any finite size $n>2$, the probability space (...) $(\cS,p)$ can be embedded into a larger probability space in such a manner that the larger space contains a Reichenbachian common cause system of size $n$ for the correlation. It also is shown that every totally ordered subset in the partially ordered set of all partitions of \cS$ contains only one Reichenbachian common cause system. Some open problems concerning Reichenbachian common cause systems are formulated. (shrink)

A partition $\{C_i\}_{i\in I}$ of a Boolean algebra Ω in a probability measure space (Ω, p) is called a Reichenbachian common cause system for the correlation between a pair A,B of events in Ω if any two elements in the partition behave like a Reichenbachian common cause and its complement; the cardinality of the index set I is called the size of the common cause system. It is shown that given any non-strict correlation in (Ω, p), and given any finite (...) natural number n > 2, the probability space (Ω,p) can be embedded into a larger probability space in such a manner that the larger space contains a Reichenbachian common cause system of size n for the correlation. (shrink)

The common cause principle says that every correlation is either due to a direct causal effect linking the correlated entities or is brought about by a third factor, a so-called common cause. The principle is of central importance in the philosophy of science, especially in causal explanation, causal modeling and in the foundations of quantum physics. Written for philosophers of science, physicists and statisticians, this book contributes to the debate over the validity of the common cause principle, by proving results (...) that bring to the surface the nature of explanation by common causes. It provides a technical and mathematically rigorous examination of the notion of common cause, providing an analysis not only in terms of classical probability measure spaces, which is typical in the available literature, but in quantum probability theory as well. The authors provide numerous open problems to further the debate and encourage future research in this field. (shrink)

In the paper it will be shown that Reichenbach’s Weak Common Cause Principle is not valid in algebraic quantum field theory with locally finite degrees of freedom in general. Namely, for any pair of projections A, B supported in spacelike separated double cones ${\mathcal{O}}_{a}$ and ${\mathcal{O}}_{b}$ , respectively, a correlating state can be given for which there is no nontrivial common cause (system) located in the union of the backward light cones of ${\mathcal{O}}_{a}$ and ${\mathcal{O}}_{b}$ and commuting with the both (...) A and B. Since noncommuting common cause solutions are presented in these states the abandonment of commutativity can modulate this result: noncommutative Common Cause Principles might survive in these models. (shrink)

Bell inequalities, understood as constraints between classical conditional probabilities, can be derived from a set of assumptions representing a common causal explanation of classical correlations. A similar derivation, however, is not known for Bell inequalities in algebraic quantum field theories establishing constraints for the expectation of specific linear combinations of projections in a quantum state. In the paper we address the question as to whether a ‘common causal justification’ of these non-classical Bell inequalities is possible. We will show that although (...) the classical notion of common causal explanation can readily be generalized for the non-classical case, the Bell inequalities used in quantum theories cannot be derived from these non-classical common causes. Just the opposite is true: for a set of correlations there can be given a non-classical common causal explanation even if they violate the Bell inequalities. This shows that the range of common causal explanations in the non-classical case is wider than that restricted by the Bell inequalities. (shrink)

This article examines the methodology of a core branch of contemporary political theory or philosophy: “analytic” political theory. After distinguishing political theory from related fields, such as political science, moral philosophy, and legal theory, the article discusses the analysis of political concepts. It then turns to the notions of principles and theories, as distinct from concepts, and reviews the methods of assessing such principles and theories (e.g., the reflective-equilibrium method), for the purpose of justifying or criticizing them. Finally, it looks (...) at a recent debate on how abstract and idealized political theory should be, and assesses the significance of disagreement in political theory. The discussion is carried out from an angle inspired by the philosophy of science. (shrink)

In the paper the relation between the standard probabilistic characterization of the common cause and Bell's notion of local causality will be investigated. It will be shown that the probabilistic common cause follows from local causality if one accepts, as Bell did, two assumptions concerning the common cause: first, the common cause is localized in the intersection of the past of the correlating events; second, it provides a complete specification of the `beables' of this intersection. However, neither assumptions are a (...) priori requirements. In the paper the logical role of these assumptions will be studied and it will be shown that only the second assumption is necessary for the derivation of the probabilistic common cause from local causality. (shrink)

I propose that paradigmatic cases of self-deception satisfy the following conditions: (a) the person who is self-deceived about not-P pretends (in the sense of makes-believe or imagines or fantasizes) that not-P is the case, often while believing that P is the case and not believing that not-P is the case; (b) the pretense that not-P largely plays the role normally played by belief in terms of (i) introspective vivacity and (ii) motivation of action in a wide range of circumstances. Understanding (...) self-deception in this way is highly natural. And it provides a non-paradoxical characterization of the phenomenon that explains both its distinctive patterns of instability and its ordinary association with irrationality. Why, then, has this diagnosis been overlooked? I suggest that the oversight is due to a failure to recognize the philosophical significance of a crucial fact about the human mind, namely, the degree to which attitudes other than belief often play a central role in our mental and practical lives, both by "influenc[ing our]... passions and imagination," and by "governing.. .our actions.". (shrink)

I shall argue that there is no such property of an event as its “probability.” This is why standard interpretations cannot give a sound definition in empirical terms of what “probability” is, and this is why empirical sciences like physics can manage without such a definition. “Probability” is a collective term, the meaning of which varies from context to context: it means different — dimensionless [0, 1]-valued — physical quantities characterising the different particular situations. In other words, probability is a (...) reducible concept, supervening on physical quantities characterising the state of affairs corresponding to the event in question. On the other hand, however, these “probability-like” physical quantities correspond to objective features of the physical world, and are objectively related to measurable quantities like relative frequencies of physical events based on finite samples — no matter whether the world is objectively deterministic or indeterministic. (shrink)

In a recent book, Logical Form: between Logic and Natural Language, Andrea Iacona argues that semantic form and logical form are distinct. The semantic form of a sentence is something that (together with the meanings of its parts) determines what it means; the logical from of a sentence is something that (all by itself) determines whether it is a logical truth. Semantic form does not depend on context but logical form does: for example, whether ‘This is this’ is a logical (...) truth depends on whether the two occurrences of ‘this’ are used to demonstrate the same individual. I respond by claiming that logical form is indifferent to reference and is sensitive only to obligatory co-reference. When the speaker intends both occurrences of ‘this’ to be interpreted the same way the logical from of ‘This is this’ is a=a, while in a context where the speaker has no such intention it is a=b. This proposal allows a much more conservative revision of the traditional picture than the one suggested by Iacona. Instead of identifying the logical form of a natural language sentence by seeking a formalization in an artificial language, we obtain it through abstraction from its syntactic analysis: replacing the non-logical expressions by schematic letters, making sure that we use identical ones if and only if the speaker intended co-reference. (shrink)

…entities? 2. How to be a nominalist 2.1. “Speak with the vulgar …” 2.2. “…think with the learned” 3. Arguments for nominalism 3.1. Intelligibility, physicalism, and economy 3.2. Causal..

Philosophers and linguists alike tend to call a semantic theory ‘Russellian’ just in case it assigns to sentences in which definite descriptions occur the truth-conditions Russell did in ‘On Denoting’. This is unfortunate; not all aspects of those particular truth-conditions do explanatory work in Russell's writings. As far as the semantics of descriptions is concerned, the key insights of ‘On Denoting’ are that definite descriptions are not uniformly referring expressions, and that they are scope-bearing elements. Anyone who accepts these two (...) claims can account for Russell's puzzle cases the way he did. Russell had no substantive argument for the claim that ‘The F is G’ entails ‘There is at most one F’; in fact, he had important misgivings about it. I outline an argument against this claim, and I argue that by holding on to uniqueness contemporary semanticists make a momentous mistake: they keep the illusion alive that there is a way to account for linguistic meaning without addressing what linguistic expressions are for. (shrink)

In this paper, we provide a comprehensive survey of the space of possible analyses of the phenomenon of quantifier domain restriction, together with a set of considerations which militate against all but our own proposal. Among the many accounts we consider and reject are the ‘explicit’ approach to quantifier domain restric‐tion discussed, for example, by Stephen Neale, and the pragmatic approach to quantifier domain restriction proposed by Kent Bach. Our hope is that the exhaustive discussion of this special case of (...) context‐dependence will provide guidelines for how to decide, for an arbitrary case of context‐dependent discourse, whether it should be treated syntactically, semantically, or pragmatically. (shrink)

Knowledge ascriptions seem context sensitive. Yet it is widely thought that epistemic contextualism does not have a plausible semantic implementation. We aim to overcome this concern by articulating and defending an explicit contextualist semantics for ‘know,’ which integrates a fairly orthodox contextualist conception of knowledge as the elimination of the relevant alternatives, with a fairly orthodox “Amherst” semantics for A-quantification over a contextually variable domain of situations. Whatever problems epistemic contextualism might face, lack of an orthodox semantic implementation is not (...) among them. (shrink)

A recent analysis by de Barros and Suppes of experimentally realizable GHZ correlations supports the conclusion that these correlations cannot be explained by introducing local hidden variables. We show, nevertheless, that their analysis does not exclude local hidden variable models in which the inefficiency in the experiment is an effect not only of random errors in the detector equipment, but is also the manifestation of a pre-set, hidden property of the particles ("prism models"). Indeed, we present an explicit prism model (...) for the GHZ scenario; that is, a local hidden variable model entirely compatible with recent GHZ experiments. (shrink)

This article is a brief formulation of a radical thesis. We start with the formalist doctrine that mathematical objects have no meanings; we have marks and rules governing how these marks can be combined. That's all. Then I go further by arguing that the signs of a formal system of mathematics should be considered as physical objects, and the formal operations as physical processes. The rules of the formal operations are or can be expressed in terms of the laws of (...) physics governing these processes. In accordance with the physicalist understanding of mind, this is true even if the operations in question are executed in the head. A truth obtained through (mathematical) reasoning is, therefore, an observed outcome of a neuro-physiological (or other physical) experiment. Consequently, deduction is nothing but a particular case of induction. (shrink)

It is shown that, given any finite set of pairs of random events in a Boolean algebra which are correlated with respect to a fixed probability measure on the algebra, the algebra can be extended in such a way that the extension contains events that can be regarded as common causes of the correlations in the sense of Reichenbach's definition of common cause. It is shown, further, that, given any quantum probability space and any set of commuting events in it (...) which are correlated with respect to a fixed quantum state, the quantum probability space can be extended in such a way that the extension contains common causes of all the selected correlations, where common cause is again taken in the sense of Reichenbach's definition. It is argued that these results very strongly restrict the possible ways of disproving Reichenbach's Common Cause Principle. (shrink)

In 1935, Einstein, Podolsky, and Rosen (EPR) published an important paper in which they claimed that the whole formalism of quantum mechanics together with what they called a “Reality Criterion” imply that quantum mechanics cannot be complete. That is, there must exist some elements of reality that are not described by quantum mechanics. They concluded that there must be a more complete description of physical reality involving some hidden variables that can characterize the state of affairs in the world in (...) more detail than the quantum mechanical state. This conclusion leads to paradoxical results. -/- As Bell proved in 1964, under some further but quite plausible assumptions, this conclusion that there are hidden variables implies that, in some spin-correlation experiments, the measured quantum mechanical probabilities should satisfy particular inequalities (Bell-type inequalities). The paradox consists in the fact that quantum probabilities do not satisfy these inequalities. And this paradoxical fact has been confirmed by several laboratory experiments since the 1970s. -/- Some researchers have interpreted this result as showing that quantum mechanics is telling us nature is non-local, that is, that particles can affect each other across great distances in a time too brief for the effect to have been due to ordinary causal interaction. Others object to this interpretation, and the problem is still open and hotly debated among both physicists and philosophers. It has motivated a wide range of research from the most fundamental quantum mechanical experiments through foundations of probability theory to the theory of stochastic causality as well as the metaphysics of free will. (shrink)

The problem of imaginative resistance holds interest for aestheticians, literary theorists, ethicists, philosophers of mind, and epistemologists. We present a somewhat opinionated overview of the philosophical discussion to date. We begin by introducing the phenomenon of imaginative resistance. We then review existing responses to the problem, giving special attention to recent research directions. Finally, we consider the philosophical significance that imaginative resistance has—or, at least, is alleged to have—for issues in moral psychology, theories of cognitive architecture, and modal epistemology.

When we utter sentences containing quantifiers, typically we are not to be taken to speak about absolutely everything there is. Suppose Mary has invited her friend John to a party to which she is going. If, upon entering the party, Mary turns to Jack and utters (1), it would be rather odd of Jack to object by pointing out that John in fact knows several people who are not present.

On the basis of what I call physico-formalist philosophy of mathematics, I will develop an amended account of the Kantian–Reichenbachian conception of constitutive a priori. It will be shown that the features attributed to a real object are not possessed by the object as a “thing-in-itself”; they require a physical theory by means of which these features are constituted. It will be seen that the existence of such a physical theory implies that a physical object can possess a property only (...) if other contingently existing physical objects exist; therefore, the intrinsic–extrinsic distinction is flawed. (shrink)

This essay has two main claims about EPR’s Reality Criterion. First, we claim that the application of the Reality Criterion makes an essential difference between the EPR argument and Einstein’s later arguments against quantum mechanics. We show that while the EPR argument, making use of the Reality Criterion, does derive that certain interpretations of quantum mechanics are incomplete, Einstein’s later arguments, making no use of the Reality Criterion, do not prove incompleteness, but rather point to the inadequacy of the Copenhagen (...) interpretation. We take this fact as an indication that the Reality Criterion is a crucial, indispensable component of the incompleteness argument(s). The second claim is more substantive. We argue that the Reality Criterion is a special case of the Common Cause Principle. Finally, we relate this proposal to Tim Maudlin’s recent assertion that the Reality Criterion is an analytic truth. (shrink)

Standard derivations of the Bell inequalities assume a common common cause system that is a common screener-off for all correlations and some additional assumptions concerning locality and no-conspiracy. In a recent paper (Grasshoff et al., 2005) Bell inequalities have been derived via separate common causes assuming perfect correlations between the events. In the paper it will be shown that the assumptions of this separate-common-cause-type derivation of the Bell inequalities in the case of perfect correlations can be reduced to the assumptions (...) of common-common-cause-system-type derivation. However, in the case of non-perfect correlations a non-reducible separate-common-cause-type derivation of some Bell-like inequalities can be given. The violation of these Bell-like inequalities proves Szabó's (2000) conjecture concerning the non-existence of a local, non-conspiratorial, separate-common-cause-model for a delta δ-neighborhood of perfect EPR correlations. (shrink)

A condition is formulated in terms of the probabilities of two pairs of correlated events in a classical probability space which is necessary for the two correlations to have a single (Reichenbachian) common-cause and it is shown that there exists pairs of correlated events probabilities of which violate the necessary condition. It is concluded that different correlations do not in general have a common common-cause. It is also shown that this conclusion remains valid even if one weakens slightly Reichenbach's definition (...) of common-cause. The significance of the difference between common-causes and common common-causes is emphasized from the perspective of Reichenbach's Common Cause Principle. (shrink)

I will argue that Kochen-Specker arguments do not provide an algebraic proof for quantum contextuality since, for the argument to be effective, operators must be uniquely associated with measur...

I will argue that the Peres-Mermin square does not necessarily rule out a value-definite (deterministic) noncontextual hidden variable model if the operators are not given a physical interpretation satisfying the following two requirements: (i) each operator is uniquely realized by a single physical measurement; (ii) commuting operators are realized by simultaneous measurements. To underpin this claim, I will construct three hidden variable models for three different physical realizations of the Peres-Mermin square: one violating (i), another violating (ii), and a third (...) one violating both (i) and (ii). (shrink)

Standard derivations of the Bell inequalities assume a common-commoncause-system that is a common screener-off for all correlations and some additional assumptions concerning locality and no-conspiracy. In a recent paper Graßhoff et al., "The British Journal for the Philosophy of Science", 56, 663–680 ) Bell inequalities have been derived via separate common causes assuming perfect correlations between the events. In the paper it will be shown that the assumptions of this separate-common-cause-type derivation of the Bell inequalities in the case of perfect (...) correlations can be reduced to the assumptions of a common-common-cause-system-type derivation. However, in the case of non-perfect correlations a non-reducible separate-common-cause-type derivation of some Bell-like inequalities can be given. The violation of these Bell-like inequalities proves Szabo's ) conjecture concerning the non-existence of a local, non-conspiratorial, separate-common-cause-model for a δ-neighborhood of perfect EPR correlations. (shrink)

We show that true first-order arithmetic of the positive integers is interpretable over the real-algebraic structure of Scott's topological model for intuitionistic analysis. From this the undecidability of the structure follows.

In 2007, a debate took place between Hungarian representatives of the analytic and continental schools of philosophy. Boldizsár Eszes and János T?zsér concluded their article about the history of analytic philosophy by the claim that the only possible method of philosophising is analytic. Answering on behalf of continental philosophers, Tibor Schwendtner approached the topic from the points of view of the sociology of knowledge and academic politics. Tamás Ullmann also defended continental philosophy, emphasizing that it is not vague or unscientific. (...) István Faragó-Szabó, in opposition to the continental position, represented a third, independent point of view. In their answer to Scwendtner, Eszes and T?zsér reject his charges, providing extensive evidence against them. (shrink)