Balancing patient rights with patient safety is a nuanced challenge. Restraint use, in particular, poses unique ethical challenges for healthcare systems. Realizing this, the American Nurses Associ...

The hippocampal formation is a structure critical to navigation and many forms of memory. In mammals, the firing of place cells is widely regarded as the fundamental unit of HF information processing. Supporting homology between the avian and mammalian HF, context-specific patterns of Egr1 have been reported in birds that are comparable to those produced by place cell firing in mammals. Recent electrophysiological data, however, suggest that many avian species lack place cells, potentially undermining the correspondence between Egr1 and place (...) cell-related firing in the avian brain. To clarify this, the current study examines Egr1 expression in Japanese quail under conditions known to elicit only weakly spatially modulated firing patterns and report robust context-dependent Egr1 expression. These data confirm that context-dependent expression of Egr1 is not dependent on precise place fields and provide insight into how these birds are able to perform complex spatial tasks despite lacking mammalian-like place cells. (shrink)

Roots presents articles on major discoveries that laid the basis for contemporary molecular and cellular biology. In this article, Norton D. Zinder reviews the first findings about the single‐stranded DNA‐containing bacteriophages and what is known today about the genetics and molecular biology of these phages.

This essay seeks to define and conceptualize cinematic quotation against scholarship that positions the auteur as the locus of meaning for a given film, especially with respect to any intertextual references. By troubling a reliance on frameworks of pathological, singular control and revealing their inability to define the specific characteristics of quotation - beyond merely thinking of it as one form of allusion or intertextuality - this essay argues that an ontological friction is inherent to instances of cinematic quotation. By (...) utilizing Jean-Luc Nancy's ontology, I am able to reveal the problematic nature of positing a singular, authorial voice in cinema or, more broadly, of assuming a singular subject at all. What is at stake in instances of cinematic quotation, as this essay shows, is the revelation that our being cannot be thought of in singular terms because we are always already both singular and plural, despite our attempts to escape such knowledge. (shrink)

David and Mary Norton present the definitive scholarly edition of Hume's Treatise, one of the greatest philosophical works ever written. This set comprises the two volumes of texts and editorial material, which are also available for purchase separately. -/- David Hume (1711 - 1776) is one of the greatest of philosophers. Today he probably ranks highest of all British philosophers in terms of influence and philosophical standing. His philosophical work ranges across morals, the mind, metaphysics, epistemology, religion, and aesthetics; (...) he had broad interests not only in philosophy as it is now conceived but in history, politics, economics, religion, and the arts. He was a master of English prose. -/- The Clarendon Hume Edition will include all of his works except his History of England and minor historical writings. It is the only thorough critical edition, and will provide a far more extensive scholarly treatment than any previous editions. This edition (which has been in preparation since the 1970s) offers authoritative annotation, bibliographical information, and indexes, and draws upon the major advances in textual scholarship that have been made since the publication of earlier editions - advances both in the understanding of editorial principle and practice and in knowledge of the history of Hume's own texts. (shrink)

Reply to Steven Lestition's article, "Countering, Transposing, or Negating the Enlightenment? A Response to Robert Norton," published in the Journal of the History of Ideas(2007), pp. 659-81.

Use of the word "Counter-Enlightenment" has become increasingly frequent in scholarly and journalistic writing. The word was almost certainly invented by the late Sir Isaiah Berlin, and it is owing to his enormous prestige and on-going influence that it has gained its current familiarity. In Berlin's view, two of the most important sources of the supposed Counter-Enlightenment are J. G. Hamann and J. G. Herder. But as I show, Berlin's numerous accounts of their thought are profoundly flawed and reflect not (...) Herder's or Hamann's own thought, but rather that of late nineteenth- and early twentieth-century German historians, who wished to legitimate their own anti-democratic, and hence anti-Enlightenment, ideology through the construction of a false historical genealogy. (shrink)

Is there progress in philosophy? If so, how much? Philosophers have recently argued for a wide range of answers to these questions, from the view that there is no progress whatsoever to the view that philosophy has provided answers to all the big philosophical questions. However, these views are difficult to compare and evaluate, because they rest on very different assumptions about the conditions under which philosophy would make progress. This paper looks to the comparatively mature debate about scientific progress (...) for inspiration on how to formulate four distinct accounts of philosophical progress, in terms of truthlikeness, problem-solving, knowledge, and understanding. Equally importantly, the paper outlines a common framework for how to understand and evaluate these accounts. We distill a series of lessons from this exercise, to help pave the way for a more fruitful discussion about philosophical progress in the future. (shrink)

In recent years, several philosophers have argued that their discipline makes no progress (or not enough in comparison to the “hard sciences”). A key argument for this pessimistic position appeals to the purported fact that philosophers widely and systematically disagree on most major philosophical issues. In this paper, we take a step back from the debate about progress in philosophy specifically and consider the general question: How (if at all) would disagreement within a discipline undermine that discipline’s progress? We reject (...) two arguments from disagreement to a lack of progress, and spell out two accounts of progress on which progress is compatible with disagreements that persist or increase over time. However, we also argue that disagreement can undermine our ability to tell which developments are progressive (and to what degree). So, while disagreement can indeed be a threat to progress, the precise nature of the threat has not been appreciated. (shrink)

David and Mary Norton present the definitive scholarly edition of Hume's Treatise, one of the greatest philosophical works ever written. The first volume contains the critical text of David Hume's Treatise of Human Nature , followed by the shortin which Hume set out the key arguments of the larger work; the volume concludes with A Letter from a Gentleman to his Friend in Edinburgh , Hume's later defence of the Treatise.

David and Mary Norton present the definitive scholarly edition of Hume's Treatise, one of the greatest philosophical works ever written. This second volume contains their historical account of how the Treatise was written and published; an explanation of how they have established the text; an extensive set of annotations which illuminate Hume's texts; and a comprehensive bibliography and index.

Religious Pluralism Religious pluralism, broadly construed, is a response to the diversity of religious beliefs, practices, and traditions that exist both in the contemporary world and throughout history. The terms “pluralism” and “pluralist” can, depending on context or intended use, signify anything from the mere fact of religious diversity to a particular kind of philosophical … Continue reading Pluralism, Religious →.

An infinite lottery machine is used as a foil for testing the reach of inductive inference, since inferences concerning it require novel extensions of probability. Its use is defensible if there is some sense in which the lottery is physically possible, even if exotic physics is needed. I argue that exotic physics is needed and describe several proposals that fail and at least one that succeeds well enough.

Responding to a major pandemic and planning for allocation of scarce resources under crisis standards of care requires coordination and cooperation across federal, state and local governments in tandem with the larger societal infrastructure. Maryland remains one of the few states with no state-endorsed ASR plan, despite having a plan published in 2017 that was informed by public forums across the state. In this article, we review strengths and weaknesses of Maryland’s response to COVID-19 and the role of the Maryland (...) Healthcare Ethics Committee Network in bridging gaps in the state’s response to prepare health care facilities for potential implementation of ASR plans. Identified “lessons learned” include: Deliberative Democracy Provided a Strong Foundation for Maryland’s ASR Framework; Community Consensus is Informative, Not Normative; Hearing Community Voices Has Inherent Value; Lack of Transparency & Political Leadership Gaps Generate a Fragmented Response; Pandemic Politics Requires Diplomacy & Persistence; Strong Leadership is Needed to Avoid Implementing ASR … And to Plan for ASR; An Effective Pandemic Response Requires Coordination and Information-Sharing Beyond the Acute Care Hospital; and The Ability to Correct Course is Crucial: Reconsidering No-visitor Policies. (shrink)

David Hume is, arguably, the most important philosopher ever to have written in English. Although best known for his contributions to epistemology, metaphysics, and the philosophy of religion, Hume also made substantial and influential contributions to psychology and the philosophy of mind, ethics, the philosophy of science, political and economic theory, political and social history, and, to a lesser extent, aesthetic and literary theory. All facets of Hume's output are discussed in this volume, the first genuinely comprehensive overview of his (...) work. The picture that emerges is of a thinker who, though critical to the point of scepticism, was nonetheless able to build on that scepticism a profoundly important, and still viable, constructive philosophy. (shrink)

Introduction -- Membership -- Employment -- Property disputes -- The family -- Goods and services -- Conclusion.

David and Mary Norton present the definitive scholarly edition of one of the greatest philosophical works ever written. This second volume begins with their 'Historical Account' of the Treatise, an account that runs from the beginnings of the work to the period immediately following Hume's death in 1776, followed by an account of the Nortons' editorial procedures and policies and a record of the differences between the first-edition text of the Treatise and the critical text that follows. The volume (...) continues with an extensive set of 'Editors' Annotations', intended to illuminate Hume's texts; a four-part bibliography of materials cited in both volumes; and a comprehensive index. (shrink)

David and Mary Norton present the definitive scholarly edition of one of the greatest philosophical works ever written. This first volume contains the critical text of David Hume's Treatise of Human Nature, followed by the shortin which Hume set out the key arguments of the larger work; the volume concludes with A Letter from a Gentleman to his Friend in Edinburgh, Hume's defence of the Treatise when it was under attack from ministers seeking to prevent Hume's appointment as Professor (...) of Moral Philosophy at the University of Edinburgh. (shrink)

My interest is to examine the nature of mind in relation to value, for I suspect that the neglect by the psychologist of the true status of value has deterred his work in two respects: first, that it has prevented a genuine theory of mind's being arrived at, and secondly that it has prevented him in his clinical work from achieving for the individual the fuller expression of mind or self that makes for satisfaction or happiness.

Kristie Miller and James Norton present a new account of metaphysical explanation, not as a philosophical technicality but as a feature of everyday life. This is the notion that we all use in ordinary contexts when we give explanations of a certain sort: Miller and Norton build their account on investigation of these explanatory practices.

Supply‐side economists claim that a low top marginal income‐tax rate accelerates investment, employment, and economic growth. But the economic literature cited to support the supply‐side hypothesis provides little to no empirical support for it. And a more comprehensive empirical examination of key parameters of U.S. economic performance in the postwar period, undertaken here, shows no association between low top marginal income‐tax rates and high real growth in investment, employment, or GDP. By contrast, the analysis yields strong evidence for the economic‐growth (...) benefits of a “demand‐side” approach to taxation policy. (shrink)

In this paper we provide a psychological explanation for ‘grounding observations’—observations that are thought to provide evidence that there exists a relation of ground. Our explanation does not appeal to the presence of any such relation. Instead, it appeals to certain evolved cognitive mechanisms, along with the traditional modal relations of supervenience, necessitation and entailment. We then consider what, if any, metaphysical conclusions we can draw from the obtaining of such an explanation, and, in particular, if it tells us anything (...) about whether we ought to posit a relation of ground. (shrink)

Spacetime substantivalism leads to a radical form of indeterminism within a very broad class of spacetime theories which include our best spacetime theory, general relativity. Extending an argument from Einstein, we show that spacetime substantivalists are committed to very many more distinct physical states than these theories' equations can determine, even with the most extensive boundary conditions.

Many think that sentences about what metaphysically explains what are true iff there exist grounding relations. This suggests that sceptics about grounding should be error theorists about metaphysical explanation. We think there is a better option: a theory of metaphysical explanation which offers truth conditions for claims about what metaphysically explains what that are not couched in terms of grounding relations, but are instead couched in terms of, inter alia, psychological facts. We do not argue that our account is superior (...) to grounding-based accounts. Rather, we offer it to those already ill-disposed towards grounding. (shrink)

This paper offers a new account of metaphysical explanation. The account is modelled on Kitcher’s unificationist approach to scientific explanation. We begin, in Sect. 2, by briefly introducing the notion of metaphysical explanation and outlining the target of analysis. After that, we introduce a unificationist account of metaphysical explanation before arguing that such an account is capable of capturing four core features of metaphysical explanations: irreflexivity, non-monotonicity, asymmetry and relevance. Since the unificationist theory of metaphysical explanation inherits irreflexivity and non-monotonicity (...) directly from the unificationist theory of scientific explanation that underwrites it, we focus on demonstrating how the account can secure asymmetry and relevance. (shrink)